triazoles has been researched along with isavuconazole in 339 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 20 (5.90) | 29.6817 |
| 2010's | 201 (59.29) | 24.3611 |
| 2020's | 118 (34.81) | 2.80 |
| Authors | Studies |
|---|---|
| Denning, DW; Sharp, A; Warn, PA | 1 |
| Beglinger, C; Brown, T; Heep, M; Roehrle, M; Roos, B; Schleimer, M; Schmitt-Hoffmann, A; Weidekamm, E | 1 |
| Brown, T; Heep, M; Maares, J; Roehrle, M; Roos, B; Schmitt-Hoffmann, A; Spickerman, J; Weidekamm, E | 1 |
| Donzelli, M; Fullhardt, P; Gebhardt, K; Klauer, D; Schleimer, M; Schmitt-Hoffmann, A; Spickermann, J; Sturm-Haurany, R; Wind, M | 1 |
| Odds, FC | 1 |
| Denning, DW; Heep, M; Mosquera, J; Schmitt-Hoffmann, A; Sharp, A; Spickermann, J; Warn, PA | 1 |
| Aurbach, U; Cornely, O; Seifert, H; Stefanik, D | 1 |
| Boekhout, T; Curfs-Breuker, I; Fernández, CM; Illnait-Zaragozi, MT; Martínez, GF; Meis, JF | 1 |
| Bouza, E; Guinea, J; Peláez, T; Recio, S; Torres-Narbona, M | 1 |
| Aller, AI; Cantón, E; García Martos, P; López-Oviedo, E; Martín de la Escalera, C; Martín-Mazuelos, E; Martos, AI; Pemán, J; Romero, A | 1 |
| Fothergill, AW; Patterson, TF; Thompson, GR; Vallor, AC; Wickes, BL; Wiederhold, NP | 2 |
| Denning, DW; Majithiya, J; Parmar, A; Sharp, A; Warn, PA | 1 |
| Bouza, E; Guinea, J | 1 |
| González, GM | 1 |
| Lass-Flörl, C; Lechner, V; Perkhofer, S | 1 |
| Fothergill, A; Patterson, TF; Sutton, DA; Thompson, GR; Wiederhold, NP | 1 |
| Denning, DW; Hope, WW; Majithiya, J; Parmar, A; Sharp, A; Warn, PA | 1 |
| Ghannoum, MA; González, GM; Guinea, J; Heep, M; Lass-Flörl, C; Verweij, PE; Warn, P; Wiedrhold, NP | 1 |
| Edwards, DJ; Heep, M; Peterfaí, E; Roos, B; Schmitt-Hoffmann, A; Spickermann, J; Stoeckel, K | 1 |
| Badali, H; De Hoog, GS; Illnait-Zaragozi, MT; Meis, JF; Najafzadeh, MJ | 1 |
| Goldani, LZ; Pasqualotto, AC; Thiele, KO | 1 |
| Thompson, GR; Wiederhold, NP | 1 |
| Bouza, E; Escribano, P; Gama, B; Guinea, J; Peláez, T; Recio, S | 1 |
| Arisawa, M; Fujii, T; Inagaki, Y; Kobayashi, K; Ohwada, J; Page, MG; Shimma, N; Tsukazaki, M; Umeda, I; Yamazaki, T | 1 |
| Bartlett, KH; Boekhout, T; Geertsen, E; Hagen, F; Illnait-Zaragozi, MT; Klaassen, CH; Meis, JF; Swinne, D | 1 |
| Sheng, CQ; Wang, SZ; Zhang, WN | 1 |
| Türel, O | 1 |
| Chakrabarti, A; Geertsen, E; Meis, JF; Mouton, JW; Shivaprakash, MR | 1 |
| Chakrabarti, A; Geertsen, E; Meis, JF; Mouton, JW; Rudramurthy, SM | 1 |
| Hope, W; Livermore, J | 1 |
| Ahmed, S; de Hoog, GS; Feng, P; Klaassen, CH; Lai, W; Lu, C; Meis, JF; Najafzadeh, MJ; Sun, J; Xi, L | 1 |
| Curfs-Breuker, I; Fahal, AH; Kloezen, W; Meis, JF; van de Sande, WW | 1 |
| Badali, H; Curfs-Breuker, I; de Hoog, GS; Deng, S; Liao, W; Meis, JF; Najafzadeh, MJ; Pan, B; Yang, L | 1 |
| Chowdhary, A; Kathuria, S; Khan, N; Kumar, DA; Meis, JF; Muralidhar, S; Prakash, A; Randhawa, HS; Sharma, C; Singh, PK; Wankhede, S | 1 |
| Chowdhary, A; Espinel-Ingroff, A; Gonzalez, GM; Lass-Flörl, C; Martin-Mazuelos, E; Meis, J; Peláez, T; Pfaller, MA; Turnidge, J | 1 |
| Castanheira, M; Jones, RN; Messer, SA; Pfaller, MA; Rhomberg, PR | 2 |
| Byrnes, E; Datta, K; Garcia-Effron, G; Marr, KA; Perlin, DS; Rhee, P; Staab, JF | 1 |
| Arikan-Akdagli, S; Canton, E; Hazirolan, G; Sahin, S | 1 |
| Arendrup, MC; Cuenca-Estrella, M; Gomez-Lopez, A; Howard, SJ; Lass-Flörl, C | 1 |
| Andes, DR; Diekema, D; Lepak, AJ; Marchillo, K; VanHecker, J | 1 |
| Goodwin, J; Gregson, L; Hope, WW; Howard, SJ; Johnson, A; McEntee, L; Moore, CB; Richardson, M | 1 |
| Curfs-Breuker, I; de Hoog, GS; Feng, P; Meis, JF; Najafzadeh, MJ; Rezaei-Matehkolaei, A; Saradeghi Keisari, M; Shamsian, SA; Vicente, VA | 1 |
| Andes, DR; Lepak, AJ; Marchillo, K; Vanhecker, J | 1 |
| Ervens, J; Ghannoum, M; Graf, B; Schwartz, S | 1 |
| Gagne, LS; Gilmore, ET; Hammond, SP; Joyce, AC; Marty, FM; Peixoto, D; Soiffer, RJ | 1 |
| Edwards, JE; Gebremariam, T; Ibrahim, AS; Kovanda, L; Lee, H; Luo, G | 1 |
| Castanheira, M; Dietrich, RR; Jones, RN; Messer, SA; Pfaller, MA; Rhomberg, PR | 1 |
| Knoll, BM | 1 |
| Arendrup, MC; Cuenca-Estrella, M; Howard, S; Lass-Flörl, C; Meletiadis, J; Mouton, JW | 1 |
| Fouant, MM; Katragkou, A; Kovanda, LL; McCarthy, M; Meletiadis, J; Moradi, PW; Petraitiene, R; Petraitis, V; Roilides, E; Strauss, GE; Walsh, TJ | 1 |
| Chowdhary, A; Dolatabadi, S; Hagen, F; Kathuria, S; Meis, JF; Sharma, B; Singh, PK | 1 |
| Chowdhary, A; Espinel-Ingroff, A; Gonzalez, GM; Guinea, J; Hagen, F; Meis, JF; Thompson, GR; Turnidge, J | 1 |
| Mouton, JW; Seyedmousavi, S; Verweij, PE | 1 |
| Azie, N; Ghannoum, M; Schmitt-Hoffmann, AH; Viljoen, J | 1 |
| Böhme, A; Cornely, OA; Schmitt-Hoffmann, A; Ullmann, AJ | 1 |
| Brüggemann, RJ; Meis, JF; Melchers, WJ; Mouton, JW; Seyedmousavi, S; Verweij, PE | 1 |
| Badali, H; de Hoog, GS; Mashedi, O; Meis, JF; Mohammadi, R | 1 |
| Traynor, K | 1 |
| McCormack, PL | 1 |
| Carver, PL; Pettit, NN | 1 |
| Ananda-Rajah, MR; Kontoyiannis, D | 1 |
| Chitasombat, MN; Kontoyiannis, DP | 2 |
| Kauffman, CA; Miceli, MH | 1 |
| Chowdhary, A; Curfs-Breuker, I; de Hoog, GS; Hagen, F; Madrid, H; Meis, JF | 1 |
| Badali, H; Chowdhary, A; de Hoog, GS; Fakhim, H; Khodavaisy, S; Meis, JF | 1 |
| Aguilar, C; Alanio, A; Catherinot, E; Danion, F; DeWolf, S; Lanternier, F; Lortholary, O | 1 |
| Thompson, GR; Twarog, M | 1 |
| Chowdhary, A; Hagen, F; Kathuria, S; Meis, JF; Singh, PK | 1 |
| Arendrup, MC; Jensen, RH; Meletiadis, J | 1 |
| Coste, AT; Sanglard, D | 1 |
| Box, H; Felton, TW; Goodwin, J; Hope, WW; Johnson, A; Livermore, J; McEntee, L; Whalley, S | 1 |
| Marx, KR; Nishimoto, AT; Rogers, PD; Rybak, JM | 1 |
| Hall, RG; Payne, KD | 1 |
| Aoun, M; Baddley, JW; Bow, EJ; Cornely, OA; Giladi, M; Heinz, WJ; Herbrecht, R; Hope, W; Karthaus, M; Kontoyiannis, DP; Lee, DG; Lee, M; Lortholary, O; Maertens, JA; Maher, RM; Marr, KA; Morrison, VA; Neofytos, D; Oren, I; Patterson, TF; Raad, II; Rahav, G; Schmitt-Hoffmann, AH; Selleslag, D; Shoham, S; Thompson, GR; Ullmann, AJ; Zeiher, B | 1 |
| Slavin, MA; Thursky, KA | 1 |
| Friedman, J; Hussar, DA | 1 |
| Hope, WW; Katragkou, A; Kovanda, LL; Moradi, PW; Petraitiene, R; Petraitis, V; Strauss, GE; Walsh, TJ | 1 |
| Temesgen, Z; Walker, RC; Zeuli, JD | 1 |
| Desai, A; Mujais, S; Schmitt-Hoffmann, AH; Townsend, R | 1 |
| Azie, N; Franks, B; Goff, D; Horn, D; Khandelwal, N; Shi, F; Shorr, AF; Spalding, J | 1 |
| Antachopoulos, C; Roilides, E | 1 |
| Alangaden, GJ; Brown, JM; Chetchotisakd, P; Cornely, OA; Engelhardt, M; Fredricks, DN; Heinz, WJ; Herbrecht, R; Ito, M; Jaruratanasirikul, S; Kanj, SS; Kaufhold, A; Klimko, N; Klyasova, G; Lee, M; Maertens, JA; Maher, RM; Marty, FM; Melinkeri, SR; Mullane, KM; Oren, I; Ostrosky-Zeichner, L; Pappas, PG; Perfect, JR; Ráčil, Z; Rahav, G; Santos, R; Sasse, C; Schwartz, S; Thompson, GR; Vehreschild, JJ; Vehreschild, MJGT; Young, JH; Zeiher, B | 1 |
| Lanternier, FL; Lortholary, O; Pilmis, B | 1 |
| Bonate, P; Desai, A; Hope, WW; Kovanda, LL; Petraitiene, R; Petraitis, V; Walsh, TJ | 1 |
| Hope, WW; Kovanda, LL; Maher, R | 1 |
| Azie, N; Cornely, OA; Engelhardt, M; Kovanda, L; Lee, M; Maher, R; Ostrosky-Zeichner, L; Perfect, JR; Queiroz-Telles, F; Rendon, A; Ribeiro Dos Santos, R; Thompson, GR; Vazquez, JA | 1 |
| Akhtar, S; Bonate, P; Desai, AV; Hope, WW; Kovanda, LL; Lu, Q; Townsend, RW | 1 |
| Akhtar, S; Desai, A; Goldwater, R; Han, D; Howieson, C; Kowalski, D; Lademacher, C; Lasseter, KC; Rammelsberg, D; Townsend, R; Yamazaki, T | 1 |
| Akhtar, S; Desai, A; Goldwater, R; Han, D; Howieson, C; Kowalski, D; Lademacher, C; Pearlman, H; Rammelsberg, D; Townsend, R; Yamazaki, T | 1 |
| Hussar, DA | 1 |
| Akhtar, S; Desai, A; Groll, AH; Han, D; Howieson, C; Kato, K; Kowalski, D; Lademacher, C; Lewis, W; Mandarino, D; Pearlman, H; Townsend, R; Yamazaki, T | 1 |
| Akhtar, S; Desai, A; Dietz, AJ; Kowalski, D; Lademacher, C; Pearlman, H; Townsend, R; Yamazaki, T | 1 |
| Legendre, DP; Muzny, CA; Riley, TT; Swiatlo, E | 1 |
| Bocanegra, R; Kirkpatrick, WR; Kovanda, L; Najvar, LK; Olivo, M; Patterson, TF; Wiederhold, NP | 1 |
| Desai, A; Kowalski, D; Pearlman, H; Schmitt-Hoffmann, A; Townsend, R; Yamazaki, T | 1 |
| Bonate, PL; Desai, A; Kovanda, L; Kowalski, D; Lu, Q; Townsend, R | 1 |
| Buer, J; Dittmer, S; Houbraken, J; Rath, PM; Steinmann, J | 1 |
| Alangaden, GJ; Ordaya, EE | 1 |
| Bossaer, JB; Carico, R; Cluck, D; Harirforoosh, S; Murrell, D | 1 |
| Scott, LJ; Shirley, M | 1 |
| Cheng, M; Haidar, G; Holland, SM; Sheridan, KR; Zelazny, AM; Zerbe, CS | 1 |
| Alqarihi, A; Azie, N; Edwards, JE; Gebremariam, T; Ibrahim, AS; Uppuluri, P; Wiederhold, NP | 1 |
| Arendrup, MC; Nielsen, HV; Verweij, P | 1 |
| Azie, N; Harrington, R; Lee, E; Messali, A; Spalding, J; Wei, J; Wu, EQ; Yang, H | 1 |
| Girmenia, C; Iori, AP | 1 |
| Kim, L; Kuti, JL; Nicolau, DP; So, W; Thabit, AK | 1 |
| Desai, A; Keirns, J; Kowalski, D; Kowey, PR; Lademacher, C; Mujais, S; Parker, B; Schneidkraut, MJ; Townsend, R; Wojtkowski, T; Yamazaki, T; Yen, M | 1 |
| Billaud, E; Dannaoui, E; Fournier, D; Jullien, V; Lanternier, F; Launay, M; Lortholary, O; Toussaint, B; Woloch, C | 1 |
| Bagshaw, E; Blackney, M; Cornely, OA; Escrig, C; Heimann, SM; Kuessner, D; Posthumus, J | 1 |
| Hussain, K; Katragkou, A; Kovanda, LL; McCarthy, M; Meletiadis, J; Moradi, PW; Myint, KL; Petraitiene, R; Petraitis, V; Roilides, E; Strauss, GE; Walsh, TJ; Zaw, MH | 1 |
| Alkhazraji, S; Baldin, C; Gebremariam, T; Ibrahim, AS; Kovanda, L; Wiederhold, NP | 1 |
| Desai, AV; Engelhardt, M; Hope, WW; Kovanda, LL; Lademacher, C; Lu, Q; Maertens, J; Marty, FM | 1 |
| Cornely, OA | 1 |
| Hope, WW; Stott, KE | 1 |
| Bassetti, M; Bouza, E | 1 |
| Denis, J; Herbrecht, R; Ledoux, MP; Toussaint, E | 1 |
| Cai, Z; Ding, Z; Jiang, Y; Jin, Y; Li, R; Ni, T; Pang, L; Wang, T; Xie, F; Yu, S; Zhang, D; Zhao, J | 1 |
| Hanretty, AM; Langelier, C; Trang, TP; Yang, K | 1 |
| Hope, WW; Kolamunnage-Dona, R; Kovanda, LL; Lee, M; Maertens, J; Neely, M | 1 |
| McCarthy, MW; Walsh, TJ | 2 |
| Birch, M; Buil, JB; Law, D; Meis, JF; Melchers, WJG; Rijs, AJMM; Verweij, PE | 1 |
| Clancy, CJ; Ensor, CR; Falcione, BA; Nguyen, MH; Rivosecchi, RM; Shields, RK; Shullo, MA; Venkataramanan, R | 1 |
| Hope, WW; Hussain, K; Kovanda, LL; Maung, BBW; McCarthy, MW; Petraitiene, R; Petraitis, V; Sekhon, NK; Shaikh, N; Walsh, TJ; Zaw, MH | 1 |
| Blaich, C; Gehlen, D; Liss, B; Müller, C; Prozeller, D; Streichert, T; Wiesen, MHJ | 1 |
| Akhtar, S; Desai, A; Hale, C; Kato, K; Kowalski, D; Lademacher, C; Townsend, R; Yamazaki, T | 1 |
| Avataneo, V; Cusato, J; D'Avolio, A; De Nicolò, A; Di Perri, G; Fatiguso, G; Favata, F; Zedda, I | 1 |
| Harris, C; Morales, MK; Shoham, S | 1 |
| Andes, D; Bonate, PL; Desai, AV; Hope, WW; Kovanda, LL; Kowalski, DL; Mouton, JW; Mujais, S; Townsend, RW | 1 |
| Courbin, V; Dannaoui, E; Jullien, V; Raffetin, A | 1 |
| Brüggemann, RJM; Buil, JB; Meis, JF; Melchers, WJG; Mouton, JW; Verweij, PE; Wasmann, RE; Zoll, J | 1 |
| Wilby, KJ | 1 |
| Furukawa, M; Misawa, N; Moore, JE; Stirling, J | 1 |
| Hoenigl, M; Krause, R; Neumeister, P; Prattes, J; Wölfler, A | 1 |
| Bassetti, M; Cornely, OA; Dörfel, D; Hagel, S; Lehners, N; Mellinghoff, SC; Plis, A; Schalk, E; Vena, A | 1 |
| Cornely, OA; Croos-Dabrera, R; Engelhardt, M; Hope, W; Kontoyiannis, DP; Lademacher, C; Lortholary, O; Mullane, K; Patterson, TF; Selleslag, D | 1 |
| Connolly, P; Montejano, R; Spec, A; Wheat, LJ | 1 |
| Cangemi, G; Castagnola, E; Dufour, C; Mesini, A; Palmisani, E | 1 |
| Abagyan, R; Aksenov, A; Calvet, CM; Debnath, A; Jennings, G; Luth, MR; McKerrow, JH; Nes, WD; Podust, LM; Zhou, W | 1 |
| Ahangarkani, F; Aslani, N; Badali, H; Boekhout, T; Hagen, F; Kolecka, A; Meis, JF; Meyabadi, MF; Shokohi, T | 1 |
| Bader, O; Becker, K; Groß, U; Idelevich, EA | 1 |
| Armstrong-James, DPH; Eades, CP; Jones, A; Kelleher, P; Periselneris, J; Shah, A; Simmonds, N | 1 |
| Kabulski, GM; MacVane, SH | 1 |
| Ader, F; Aguado, JM; Akova, M; Arendrup, MC; Arikan-Akdagli, S; Barnes, RA; Beigelman-Aubry, C; Blot, S; Bouza, E; Brüggemann, RJM; Buchheidt, D; Cadranel, J; Castagnola, E; Chakrabarti, A; Cornely, OA; Cuenca-Estrella, M; Denning, DW; Dimopoulos, G; Fortun, J; Gangneux, JP; Garbino, J; Groll, AH; Heinz, WJ; Herbrecht, R; Heussel, CP; Kibbler, CC; Klimko, N; Kullberg, BJ; Lagrou, K; Lange, C; Lass-Flörl, C; Lehrnbecher, T; Lewis, RE; Löffler, J; Lortholary, O; Maertens, J; Marchetti, O; Meis, JF; Munoz, P; Pagano, L; Ribaud, P; Richardson, M; Roilides, E; Ruhnke, M; Sanguinetti, M; Sheppard, DC; Sinkó, J; Skiada, A; Ullmann, AJ; Vehreschild, MJGT; Verweij, PE; Viscoli, C; Warris, A | 1 |
| Denis, J; Herbrecht, R; Ledoux, MP; Nivoix, Y | 1 |
| Tollkuci, E | 1 |
| Chen, C; Cornely, OA; Croos-Dabrera, R; Engelhardt, M; Heep, M; Lademacher, C; Maher, R; Marty, FM; Mullane, KM; Ostrosky-Zeichner, L; Perfect, JR | 1 |
| Bartoszewicz, M; Król, J; Nawrot, U | 1 |
| Cornely, OA; Croos-Dabrera, R; Giladi, M; Lademacher, C; Lu, Q; Maher, RM; Marty, FM; Mullane, KM; Oren, I; Ostrosky-Zeichner, L; Perfect, JR; Rahav, G; Schmitt-Hoffmann, AH | 2 |
| Babik, JM; Chin-Hong, P; Doernberg, SB; Fung, M; Graff, L; Langelier, C; Lo, M; Logan, AC; Schwartz, BS; Tan, M | 1 |
| Arsiè, E; Cattaneo, D; Cozzi, V; Iavarone, M; Lampertico, P; Piconi, S | 1 |
| McCarthy, MW; Moriyama, B; Petraitiene, R; Petraitis, V; Walsh, TJ | 1 |
| Castanheira, M; Pfaller, MA; Rhomberg, PR | 1 |
| Andes, D; Desai, A; Kitt, T; Kovanda, L; Walsh, TJ; Zhao, M | 1 |
| Buchheidt, D; Hoenigl, M; Jenks, JD; Krause, R; Prattes, J; Salzer, HJ | 1 |
| Baldelli, S; Castoldi, S; Cattaneo, D; Clementi, E; Cozzi, V | 1 |
| Ding, H; Fang, L; Huang, P; Sun, J; Tong, Y; Xu, G; Zhang, Y; Zheng, X; Zhu, L | 1 |
| Bose, P; DiPippo, AJ; Kontoyiannis, DP; Rausch, CR | 1 |
| El-Najjar, N; Gessner, A; Hösl, J | 1 |
| Bagshaw, E; Blackney, M; Enoch, DA; Kuessner, D; Posthumus, J | 1 |
| Binder, U; Grässle, D; Hörtnagl, C; Lackner, M; Lass-Flörl, C; Maurer, E; Moser, P; Naschberger, V; Segal, E; Semis, M | 1 |
| Barg, AA; Bartuv, M; Greenberg, G; Keller, N; Malkiel, S; Toren, A | 1 |
| Barnes, AMT; Hansen, GT; Huebner, B; Nelson, S; Sabin, AP; Thielen, BK; Wesenberg, E | 1 |
| Loregian, A; Nannetti, G; Pagni, S; Palù, G | 1 |
| Karasch, I; Lakner, J; Mueller, SC; Wacke, R | 1 |
| Escrig, C; Herbrecht, R; Kuessner, D; Pooley, N; Posthumus, J | 1 |
| Bouza, E; Escribano, P; Gómez, A; Guinea, J; Marcos-Zambrano, LJ; Muñoz, P; Sánchez-Carrillo, C | 1 |
| Aoun, M; Cornely, OA; Engelhardt, M; Giladi, M; Heinz, WJ; Herbrecht, R; Kaufhold, A; Kovanda, L; Maertens, J; Rahav, G; Saulay, M; Selleslag, D; Ullmann, AJ | 1 |
| Cheng, MP; Cummins, KC; Davids, MS; Issa, NC; Kubiak, DW; Marty, FM | 1 |
| Andersen, LO; Arendrup, MC; Hare, RK; Irga-Jaworska, N; Jaworski, R; Jensen, HE; Malecka, A; Nielsen, HV; Pomorska, A; Radon-Proskura, J | 1 |
| Dowis, J; French, D; Smith, A | 1 |
| Alexander, MD; Armistead, PM; Daniels, LM; Kufel, WD; Ptachcinski, JR; Shaw, JR | 1 |
| Abdallah, N; Kanj, A; Soubani, AO | 1 |
| Costanzo, CM; Oliveri, S; Palermo, CI; Scalia, G; Trovato, L | 1 |
| DiPippo, AJ; Kontoyiannis, DP; Rausch, CR | 1 |
| Andes, D | 1 |
| Chetchotisakd, P; Croos-Dabrera, R; De Waele, J; Engelhardt, M; Fredericks, C; Herbrecht, R; Jaruratanasirikul, S; Kovanda, L; Kullberg, BJ; Lademacher, C; Ostrosky-Zeichner, L; Pappas, PG; Rahav, G; Rotstein, C; Sobel, JD; Thompson, GR; Van Wijngaerden, E; Vazquez, J; Viscoli, C | 1 |
| Dadwal, S; Jhangiani, K; Kieu, V; Nakamura, R; Pon, D | 1 |
| Concordet, D; Darnaud, L; Debard, A; Gandia, P; Godet, C; Lamoureux, F; Martins, P; Pontier, S; Venisse, N | 1 |
| Shen, L; Tu, F; Wang, J; Wang, R; Xia, G; Xu, J; Ye, C; Yi, Y; Yu, C; Zheng, Z | 1 |
| Andes, DR; Ghannoum, MA; Hope, WW; Jones, ME; Kovanda, LL; Lademacher, C; Lu, Q; Mukherjee, PK; Santerre Henriksen, A | 1 |
| Albert, ND; Kontoyiannis, DP; Lewis, RE; Wurster, S | 1 |
| Girmenia, C; Goffredo, BM; Marchesi, F; Mengarelli, A; Menna, P; Minotti, G; Romano, A; Salvatorelli, E | 1 |
| Andes, D; Engelhardt, M; Groll, AH; Kaindl, T; Larger, P; Saulay, M | 1 |
| Amzallag-Bellenger, E; Bruno, B; Cornu, M; Dubos, F; François, N; Lanternier, F; Loridant, S; Mazingue, F; Navarin, P; Sendid, B | 1 |
| Benjamin, DJ; Cohen, SH; Heidari, A; Hoffman, WJ; Johnson, R; Laurence, B; McHardy, I; Mu, A; Ngai, T; Quinlan, M; Thompson, GR | 1 |
| Bongomin, F; Felton, T; Maguire, N; Moore, CB; Rautemaa-Richardson, R | 1 |
| Capellier, G; Clairet, AL; Lagoutte-Renosi, J; Millon, L; Navellou, JC; Piton, G; Rougny, AC; Winiszewski, H | 1 |
| Adamsick, ML; Elshaboury, RH; Gandhi, RG; Gift, T; Kotton, CN; Mansour, MK | 1 |
| Bagshaw, E; Floros, L; Kuessner, D; Posthumus, J; Sjölin, J | 1 |
| André, P; Decosterd, LA; Guery, B; Lamoth, F; Maduri, R; Mercier, T; Pagani, JL; Pantet, O | 1 |
| Boullié, A; Bretagne, S; Desnos-Ollivier, M; Dromer, F; Gautier, C; Lortholary, O | 1 |
| Eraso, E; Gil-Alonso, S; Jauregizar, N; Marcos-Arias, C; Mateo, E; Quindós, G; Sevillano, E | 1 |
| Athans, V; Brizendine, KD; Hassouna, H | 1 |
| DiPippo, AJ; Kontoyiannis, DP | 1 |
| Evans, SL; Fish, DN; Kiser, TH; MacLaren, R; Mueller, SW; Van Matre, ET | 1 |
| Alflen, A; Aranda Lopez, P; Beckert, H; Radsak, MP; Ries, F; Schild, H; Teschner, D; Theobald, M | 1 |
| Dannaoui, E; Felske-Zech, H; Schwarz, P; Schwarz, PV | 1 |
| Fontana, L; Hakki, M; Lewis, JS; Noble, BN; Perlin, DS; Strasfeld, L; Zhao, Y | 1 |
| Desai, AV; Han, D; Kowalski, DL; Lademacher, C; Pearlman, H; Yamazaki, T | 1 |
| Dolgov, E; Lee, A; Lee, MH; Perlin, DS; Prideaux, B; Zhao, Y; Zimmerman, M | 1 |
| Bowen, CD; Hakki, M; Lewis Ⅱ, JS; Tallman, GB | 1 |
| Bruneel, F; de Roquetaillade, C; Hamon, M; Paktoris, H | 1 |
| Castagnola, E; De Leonardis, F; Giannico, B; Mariggiò, MA; Novielli, C; Santoro, N | 1 |
| Angelucci, E; Aquino, S; Di Grazia, C; Dominietto, A; Furfaro, E; Ghiggi, C; Ghiso, A; Mikulska, M; Raiola, AM; Signori, A; Ungaro, R; Viscoli, C | 1 |
| Baldelli, S; Cattaneo, D; Clementi, E; Colombo, C; Cozzi, V; Faelli, NML; Fusi, M; Russo, M | 1 |
| Alastruey-Izquierdo, A; de Hoog, S; Kurzai, O; Voigt, K; Wagner, L; Walther, G | 1 |
| Bartuska, A; de Castro, GC; Franke, KS; Giamberardino, C; Hope, WW; Kovanda, LL; McEntee, L; Perfect, JR; Ripple, K; Smilnak, G; Toffaletti, DL | 1 |
| Floros, L; Georgallis, M; Pagliuca, A; Rita Capparella, M; Sung, AH; Taie, AA; Weidlich, D | 1 |
| Kelly, DE; Kelly, SL; Nes, WD; Parker, JE; Price, CL; Rolley, NJ; Warrilow, AGS | 1 |
| Dannaoui, E; Schwarz, P; Vidal, P | 1 |
| Danion, F; Dureault, A; Goldwirt, L; Guéry, R; Herbrecht, A; Jullien, V; Lanternier, F; Lapusan, S; Lortholary, O; Morgand, M; Palmier, B; Puget, S; Rouzaud, C | 1 |
| Batres Baires, G; Heilmaier, M; Huber, W; Kinzig, M; Lahmer, T; Mayr, U; Rasch, S; Schmid, RM; Sörgel, F | 1 |
| Bellanger, AP; Berceanu, A; Daguindau, E; Desbrosses, Y; Millon, L; Rocchi, S; Scherer, E | 1 |
| Gandhi, TN; Linder, KA; Miceli, MH | 1 |
| Anguita, J; Bailén, R; Balsalobre, P; Buño, I; Diez-Martin, JL; Dorado, N; Guinea, J; Kwon, M; Machado, M; Oarbeascoa, G; Padilla, B; Pradillo, V; Sancho, M; Serrano, D | 1 |
| Angilletta, R; Corcione, S; De Rosa, FG; Lupia, T; Scabini, S | 1 |
| Brivio, E; Foresti, S; Migliorino, GM; Rovelli, A; Verna, M; Zucchini, N | 1 |
| Hennart, B; Henriksen, AS; Krause, R; Meinitzer, A; Müller, C; Pea, F; Richardson, M; Spickermann, J; Wiesen, MHJ; Wiktorowicz, T | 1 |
| Arbona-Haddad, E; Bold, TD; Chen, K; Cheng, MP; Cummins, KC; Hammond, SP; Koo, S; Kusztos, AE; Liakos, A; Marty, FM; Orejas, JL; Pandit, A; Solomon, IH | 1 |
| Cornely, OA; Hamed, K; Heinz, WJ; Herbrecht, R; Maertens, J; Marty, FM; Rahav, G; Schwartz, S | 1 |
| Baj, A; Dalla Gasperina, D; Di Rosa, Z; Grossi, PA; Lepera, V; Lombardi, D; Lombardi, G; Nava, A; Rovelli, C | 1 |
| Bhetanabhotla, SS; Regella, VRPS; Subramanian, VC | 1 |
| Bigot, J; Broutin, A; Guitard, J; Hennequin, C; Moreno-Sabater, A; Senghor, Y | 1 |
| Bigot, J; Botterel, F; Bougnoux, ME; Dannaoui, E; Dellière, S; Fekkar, A; Guitard, J; Hennequin, C; Senghor, Y; Verdurme, L | 1 |
| Calore, E; Cesaro, S; Colombini, A; Comelli, A; De Gregori, S; Decembrino, N; Giardini, I; Goffredo, BM; Molinaro, M; Muggeo, P; Perruccio, K; Scudeller, L; Soncini, E; Zecca, M | 1 |
| Guo, Y; Tang, K; Zhang, X | 1 |
| Anderson, A; Camargo, JF; Komanduri, KV; Lekakis, L; Martinez, OV; Mendoza, MA; Morris, MI; Prado, CE; Simkins, J | 1 |
| Fernandez, E; Makar, G; Perz, A; Rafferty, W; Weinstock, J | 1 |
| Carvalhaes, CG; Castanheira, M; Messer, SA; Pfaller, MA | 1 |
| Barker, J; Bogler, Y; Giralt, S; Gyurkocza, B; Lee, YJ; Papanicolaou, GA; Perales, MA; Seo, S; Shaffer, B; Stern, A; Su, Y; Tamari, R | 1 |
| Bennis, Y; Boone, M; Chouaki, T; Delette, C; Joseph, C; Mabille, C; Maizel, J; Marolleau, JP; Nyga, R | 1 |
| Debnath, A; McKerrow, JH; Podust, LM; Shing, B; Singh, S | 1 |
| Brunet, K; Cateau, E; Eestermans, R; Rodier, MH | 1 |
| Chen, J; Dadwal, S; Karras, NA; Pawlowska, A; Rosenthal, J; Ross, JA; Sun, W; Tegtmeier, B; Yamada, C; Zaia, J | 1 |
| Bivins, CA; Borthakur, G; Bose, P; Daver, N; Estrov, Z; Huang, X; Kadia, TM; Kantarjian, HM; Konopleva, M; Kontoyiannis, DP; Marx, KR; Masarova, L; McCue, D; Naqvi, K; Pemmaraju, N; Pierce, SA; Qiao, W; Rausch, CR; Ravandi, F; Takahashi, K; Wiederhold, NP; Wurster, S; Yilmaz, M | 1 |
| Agarwal, R; Dhooria, S; Muthu, V; Prasad, KT; Sehgal, IS | 1 |
| Ashkenazi-Hoffnung, L; Ben-Ami, R; Bilavsky, E; Fischer, S; Grisaru, G; Levy, I; Nahum, E; Novikov, A; Sadot, E; Scheuerman, O | 1 |
| Candoni, A; Facchin, G; Fanin, R; Lazzarotto, D | 1 |
| Böll, B; Böttiger, BW; Cornely, OA; Dusse, F; Eichenauer, DA; Fuchs, F; Hallek, M; Jung, N; Klein, F; Kochanek, M; Koehler, P; Persigehl, T; Rybniker, J; Shimabukuro-Vornhagen, A | 1 |
| Bandettini, R; Barco, S; Carrega, G; Castagnola, E; Dallorso, S; Dufour, C; Mesini, A; Miano, M; Palmisani, E; Saffioti, C | 1 |
| Assaf, A; Chopin, MC; Dozier, A; Faure, E; Faure, K; Goeminne, C; Leroy, J; Loridant, S; Panaget, S; Sermet, K; Vuotto, F | 1 |
| Borman, AM; Fraser, M; Hughes, JM; Johnson, EM; Noel, AR; Oliver, D; Sunderland, J | 1 |
| Baud, FJ; Houzé, P | 1 |
| Biagi, M; Butler, DA; Tan, X; Wenzler, E | 1 |
| Clancy, CJ; Clarke, L; Falcione, BA; Kwak, EJ; Marini, RV; McCreary, EK; Morrell, M; Nguyen, MH; Rivosecchi, RM; Sacha, L; Samanta, P; Sanchez, PG; Shields, RK; Silveira, FP; Viehman, A | 1 |
| Bedin Denardi, L; Brüggemann, RJM; Buil, JB; Melchers, WJG; Verweij, PE | 1 |
| Gómez-López, A | 1 |
| Arendrup, MC; Guinea, J; Hare, RK; Jørgensen, KM; Meletiadis, J | 1 |
| Dong, J; Li, D; Li, X; Liu, W; Mei, H; Song, N; Zheng, H | 1 |
| Álvarez Duarte, E; Salas, V | 1 |
| Beigelman-Aubry, C; Bochud, PY; Burger, R; Coste, AT; Krueger, T; Lamoth, F; Letovanec, I; Lovis, A; Spertini, O; Stavropoulou, E | 1 |
| Anderson, AD; Andes, DR; Borlagdan, J; Davis, MR; Lepak, AJ; Marini, RV; McCreary, EK; Nguyen, MH; Rivosecchi, RM; Sacha, LM; Shields, RK; Silveira, FP | 1 |
| Jacobs, SE; Rana, MM; Saunders-Hao, P; Vu, CA | 1 |
| Azanza, JR; Grau, S; López-Gómez, V; López-Ibáñez de Aldecoa, A; Peral, C; Rebollo, P; Vázquez, L | 1 |
| Cornely, OA; Jeck, J; Kron, F; Lazzaro, C; Thielscher, C; Wingen-Heimann, SM | 1 |
| Auger, C; Durà-Miralles, X; Escolà-Vergé, L; Fernández-Hidalgo, N; Lung, M; Martín-Gómez, MT; Martínez-Ricarte, F; Moreno, D | 1 |
| Aguado, JM; Andrés, A; Caravaca-Fontán, F; Fernández-Ruiz, M; Gutiérrez, E; López-Medrano, F; Morales, E; Praga, M; Sevillano, Á; Trujillo, H | 1 |
| Kram, B; Liu, B; Maziarz, E; Spivey, J; Wrenn, R | 1 |
| Bidaud, AL; Dannaoui, E; Schwarz, P | 1 |
| Finkelman, MA; Katragkou, A; Kovanda, LL; Maung, BBW; Moradi, PW; Naing, E; Petraitiene, R; Petraitis, V; Sussman-Straus, GE; Walsh, TJ | 1 |
| Clerkin, P; Kuzmic, B; Laningham, F; McCarty, J; Naeem, F | 1 |
| Bassetti, M; Böll, B; Brüggemann, R; Chakrabarti, A; Chen, SCA; Colombo, AL; Cornely, OA; Gangneux, JP; Hoenigl, M; Klimko, N; Koehler, P; Lass-Flörl, C; Meis, JF; Oladele, RO; Ostrosky-Zeichner, L; Patterson, TF; Perfect, JR; Persigehl, T; Verweij, PE; Vinh, DC; White, PL; Zhu, LP | 1 |
| Aram, JA; Cao, G; Cornely, OA; Desai, A; Fayyad, R; Guo, X; Hamed, K; Wu, D; Zhang, J; Zhang, Y | 2 |
| Dobiáš, R; Havlíček, V | 1 |
| Chiaretto, G; Cultrera, R; Mengoli, A; Perri, P; Sanguinetti, M; Sarnicola, C; Segala, D; Torelli, R | 1 |
| Al-Obaidi, M; Badali, H; Cañete-Gibas, C; Patterson, HP; Wiederhold, NP | 1 |
| Adeyemi, OA; Backous, CA; Coomes, DS; Logan, RL | 1 |
| Castanheira, M; Collingsworth, TD; Davis, AP; Deshpande, LM; Pfaller, MA | 1 |
| Celegato, M; Gribaudo, G; Lepesheva, GI; Loregian, A; Luganini, A; Mercorelli, B | 1 |
| Akbari, F; Deng, S; Houbraken, J; Najafzadeh, MJ; Naseri, A; Wang, X; Xu, X; Zhang, H; Zhao, R | 1 |
| Durand, ML; Kitt, TM; Marty, FM; Song, Y | 1 |
| Brüggemann, RJ; Debaveye, Y; Dreesen, E; Elkayal, O; Guchelaar, HJ; Lagrou, K; Spriet, I; Van Bleyenbergh, P; Van Daele, R; Vermeersch, P; Vos, R | 1 |
| Echols, CD; Garner, LM; Wilson, WS | 1 |
| Borman, AM; Forgács, L; Jakab, Á; Kovács, R; Majoros, L; Nagy, F; Nyikos, F; Tóth, Z | 1 |
| Arrieta, AC; Chen, TK; Chu, J; Danziger-Isakov, LA; Day, JC; Desai, A; Frangoul, HA; Hamed, K; Jones, ME; Kovanda, LL; Lademacher, C; McComsey, GA; Micklus, K; Muller, WJ; Neely, M; Phillips, DL; Rheingold, SR; Statler, VA; Steinbach, WJ; Sue, PK; Walsh, TJ; Yildirim, I; Yin, DE | 1 |
| Bogler, Y; Lee, YJ; Neofytos, D; Papanicolaou, GA; Perales, MA; Seo, SK; Shaffer, B; Stern, A; Su, Y | 1 |
| Colom, MF; Cuetara, MS; Garcia-Benayas, E; Hagen, F; Jusdado Ruiz-Capillas, JJ; Nuñez-Valentin, MP; Rodríguez Garcia, E; Rodriguez-Gallego, JC; Rojo-Amigo, R | 1 |
| Bonn, J; Cornely, OA; Enoch, DA; Grau, S; Jakobs, F; Jeck, J; Kron, A; Kron, F; Micallef, C; Thielscher, C; Wingen-Heimann, SM | 1 |
| Desai, A; Goldwater, R; Helmick, M; Heo, N; Martin, N; Moy, S; Stanhope, S | 1 |
| Castanheira, M; Deshpande, LM; Messer, SA; Pfaller, MA; Rhomberg, PR; Utt, EA | 1 |
| Bubalo, JS; Gu, TM; Le, H; Lewis, JS | 1 |
| Gebremariam, T; Gu, Y; Ibrahim, AS; Kitt, TM; Singh, S | 1 |
| Chalandon, Y; Glampedakis, E; Kronig, I; Masouridi-Levrat, S; Neofytos, D; Van Delden, C; Vernaz, N | 1 |
| Blokhina, S; Ol'khovich, M; Perlovich, G; Sharapova, A | 1 |
| Dumoulin, A; Van Hoecke, F; Vangheluwe, T; Vogelaers, D | 1 |
| Beauchemin, C; Claveau, D; Dufresne, SF; Guinan, K; Rotstein, C | 1 |
| Debaveye, Y; Lagrou, K; Spriet, I; Van Daele, R; Vandenbriele, C; Vos, R; Wauters, J | 1 |
| Kumar, G; Kumar, R; Kumar, S; Kumari, M; Saroha, B | 1 |
| Couraud, S; Dannaoui, E; Déméautis, T; Devouassoux, G; Dupont, D; Durieu, I; Garnier, H; Kramer, R; Lina, B; Menotti, J; Persat, F; Rabodonirina, M; Reix, P; Sénéchal, A; Simon, L; Wallon, M | 1 |
| Bozsaki, G; Dill, V; Ehmer, U; Lahmer, T; Mayr, U; Odysseos, G; Schmid, RM; Seidensticker, C | 1 |
| Dubowik, M; Duda, M; Kołaczkowska, M; Lango, R; Lango-Maziarz, A; Siondalski, P | 1 |
| Clark, NM; Croos-Dabrera, R; Fisher, CE; Garcia-Diaz, J; Greenberg, RN; Kontoyiannis, DP; Kovanda, L; Miceli, MH; Nguyen, MH; Ostrosky-Zeichner, L; Spec, A; Thompson, GR; Young, JH | 1 |
| Bernard, L; Chesnay, A; Coustillères, F; Desoubeaux, G; Doman, M; Lacasse, M; Lanternier, F; Lemaignen, A; Maisons, V | 1 |
| Buil, JB; den Dekker, BM; Festen, B; Heusinkveld, M; Melchers, M; Mooren, ERM; Schellaars, R; van Binsbergen, AL; van Bree, SHW; van Zanten, ARH; Verweij, PE | 1 |
| Chandrasekar, PH; Sivasubramanian, G | 1 |
| Berastegui, C; Bravo, C; Campany-Herrero, D; Castells, L; Deu, M; Gavaldà, J; Len, O; Los-Arcos, I; Márquez-Algaba, E; Martín-Gómez, MT; Monforte, A; Moreso, F; Nuvials, X; Sacanell, J; Sempere, A | 1 |
| Davis, MR; Dieringer, TD; Schaenman, JM | 1 |
| Kumagai, Y; Ose, A; Shirae, S | 1 |
| DiNardo, CD; DiPippo, AJ; Jiang, Y; Kadia, T; Kontoyiannis, DP; Maiti, A; Montalban-Bravo, G; Rausch, CR; Ravandi, F | 1 |
| Belotti, T; Campoli, C; Cojutti, PG; Gatti, M; Masetti, R; Pea, F; Pession, A; Viale, P | 1 |
| Kludjian, G; Miller, M; Mohrien, K; Morita, K | 1 |
| Hasegawa, S; Kozaki, T; Mori, Y; Ose, A; Shirae, S | 1 |
| Chakraborty, S; Joe, G; Soman, R | 1 |
| Bange, G; Bidaud, AL; Dannaoui, E; Nikolskiy, I; Schwarz, P; Sommer, F | 1 |
| Dear, JD; Wittenburg, LA; Woerde, DJ | 1 |
| Alali, M; Balsara, K; Barros, KL; Budnick, HC; Khaitan, A; Schulte, RR; Streicher, DA | 1 |
| Aram, JA; Bellmann, C; Hongmei, J; Inês, M; Macmillan, T; Penack, O; Ping, Y; Webb, N | 1 |
| Eller, P; Gringschl, Y; Hatzl, S; Hoenigl, M; Krause, R; Kriegl, L; Meinitzer, A; Muhr, T; Prattes, J; Reisinger, AC; Schilcher, G; Zurl, C | 1 |
| Debaveye, Y; Degezelle, K; Hermans, G; Meersseman, P; Mertens, B; Spriet, I; Van Daele, R; Van Regenmortel, N; Vandenbriele, C; Wauters, J | 1 |
| Hakki, M; Lewis, JS; Thompson, GR; Wiederhold, NP | 1 |
| Brüggemann, R; Debaveye, Y; Gijsen, M; Mertens, B; Spriet, I; Van Daele, R; Vandenbriele, C; Wauters, J | 1 |
| Hatzl, S; Hoenigl, M; Krause, R; Kriegl, L; Schilcher, G | 1 |
| Akashi, K; Izumikawa, K; Kakeya, H; Kamei, K; Kanda, Y; Kimura, SI; Kishida, M; Kohno, S; Matsuda, M; Miyazaki, T; Miyazaki, Y; Mukae, H; Niki, Y; Ogawa, K; Okada, F; Suzuki, J; Takazono, T; Taniguchi, S; Tateda, K; Yoshida, M | 1 |
| Aguado, JM; Bodro, M; Carratalà, J; Cordero, E; Fariñas, MDC; Fernández-Ruiz, M; Fortún, J; Goikoetxea, J; Gutiérrez Martín, I; Illaro, A; López-Viñau, T; Moreno, A; Muñoz, P; Ramos-Martínez, A; Rodriguez-Álvarez, R; Ruiz-Ruigómez, M; Sabé, N; Salto-Alejandre, S; Valerio, M; Vidal, E | 1 |
| Hall, R; Kincaide, E; Levine, D; Sweiss, H | 1 |
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| Cornely, OA; Franz, J; Jakobs, F; Jeck, J; Kron, A; Kron, F; Wingen-Heimann, SM | 1 |
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| Chan, CYY; Chan, YFZ; Cherng, BPZ; Chung, JS; Goh, KKK; Kwa, ALH; Lim, TP; Tan, BH; Teh, YE; Wong, GC; Zhou, YP; Zulkifli, FIB | 1 |
| Kozaki, T; Mizuhata, J; Ose, A; Shirae, S; Tsuruya, Y | 1 |
| Amin Shahidi, M; Badiee, P; Ghasemi, F; Hashemi, J; Jafarian, H; Mohammadi, R; Najafzadeh, MJ; Shokohi, T | 1 |
| Bow, EJ; Villalobos, AP | 1 |
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| Aram, JA; Engelhardt, M; Hamed, K; Huang, JJ; Kovanda, LL; Yan, J | 1 |
| Asai, N; Hagihara, M; Hirai, J; Iwamoto, T; Kato, H; Mikamo, H; Mori, N; Umemura, T; Yamagishi, Y | 1 |
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| Brüggemann, RJM; Debaveye, Y; Jansen, AME; Mertens, B; Schouten, J; Spriet, I; Ter Heine, R; Verweij, PE; Wauters, J | 1 |
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53 review(s) available for triazoles and isavuconazole
| Article | Year |
|---|---|
Drug evaluation: BAL-8557--a novel broad-spectrum triazole antifungal.
Topics: Animals; Antifungal Agents; Aspergillosis; Aspergillus; Candida; Candidiasis; Clinical Trials, Phase II as Topic; Drug Evaluation, Preclinical; Drug-Related Side Effects and Adverse Reactions; Humans; Nitriles; Pyridines; Triazoles | 2006 |
Isavuconazole: a new and promising antifungal triazole for the treatment of invasive fungal infections.
Topics: Animals; Antifungal Agents; Aspergillus; Candida; Clinical Trials as Topic; Cryptococcus neoformans; Disease Models, Animal; Mycoses; Nitriles; Pyridines; Triazoles | 2008 |
Novel triazole antifungal drugs: focus on isavuconazole, ravuconazole and albaconazole.
Topics: Animals; Antifungal Agents; Clinical Trials as Topic; Drug Resistance, Fungal; Fungi; Humans; Microbial Sensitivity Tests; Mycoses; Nitriles; Pyridines; Quinazolines; Thiazoles; Triazoles | 2010 |
Isavuconazole: a comprehensive review of spectrum of activity of a new triazole.
Topics: Animals; Antifungal Agents; Clinical Trials as Topic; Disease Models, Animal; Fungi; Humans; Mice; Microbial Sensitivity Tests; Mycoses; Nitriles; Pyridines; Triazoles | 2010 |
[Recent advances in the study of new antifungal lead compounds].
Topics: Antifungal Agents; Fungi; Heterocyclic Compounds; Humans; Lipopeptides; Molecular Structure; Mycoses; Nitriles; Plant Extracts; Plants, Medicinal; Pyridines; Quinazolines; Quinones; Structure-Activity Relationship; Thiazoles; Triazoles | 2010 |
Newer antifungal agents.
Topics: Animals; Antifungal Agents; Aspergillosis; Aspergillus; Candida; Candidiasis, Invasive; Child; Clinical Trials as Topic; Half-Life; Humans; Lipopeptides; Nitriles; Pyridines; Quinazolines; Thiazoles; Triazoles | 2011 |
Evaluation of the pharmacokinetics and clinical utility of isavuconazole for treatment of invasive fungal infections.
Topics: Animals; Antifungal Agents; Candidiasis, Invasive; Drug Interactions; Drug Resistance, Fungal; Humans; Invasive Pulmonary Aspergillosis; Nitriles; Pyridines; Treatment Outcome; Triazoles | 2012 |
Isavuconazole, a broad-spectrum triazole for the treatment of systemic fungal diseases.
Topics: Antifungal Agents; Humans; Mycoses; Nitriles; Pyridines; Triazoles | 2015 |
Isavuconazonium: first global approval.
Topics: Animals; Aspergillosis; Clinical Trials, Phase II as Topic; Clinical Trials, Phase III as Topic; Drug Approval; Humans; Mucormycosis; Nitriles; Pyridines; Randomized Controlled Trials as Topic; Triazoles | 2015 |
Isavuconazole: A New Option for the Management of Invasive Fungal Infections.
Topics: Animals; Antifungal Agents; Aspergillosis; Candidemia; Candidiasis; Candidiasis, Invasive; Clinical Trials as Topic; Drug Resistance, Fungal; Humans; Nitriles; Pyridines; Triazoles; Voriconazole | 2015 |
The 'cephalosporin era' of triazole therapy: isavuconazole, a welcomed newcomer for the treatment of invasive fungal infections.
Topics: Animals; Antifungal Agents; Clinical Trials, Phase II as Topic; Clinical Trials, Phase III as Topic; Drug Interactions; Drug Resistance, Fungal; Fungi; Humans; Immunocompromised Host; Mycoses; Nitriles; Pyridines; Triazoles | 2015 |
Isavuconazole: A New Broad-Spectrum Triazole Antifungal Agent.
Topics: Antifungal Agents; Drug-Related Side Effects and Adverse Reactions; Humans; Invasive Pulmonary Aspergillosis; Mucormycosis; Nitriles; Pyridines; Randomized Controlled Trials as Topic; Treatment Outcome; Triazoles | 2015 |
Mucormycosis: New Developments into a Persistently Devastating Infection.
Topics: Amphotericin B; Antifungal Agents; Combined Modality Therapy; Debridement; Hematopoietic Stem Cell Transplantation; Humans; Lung Diseases, Fungal; Mucorales; Mucormycosis; Nitriles; Pyridines; Triazoles | 2015 |
Coccidioidomycosis: Recent Updates.
Topics: Antifungal Agents; Coccidioides; Coccidioidomycosis; Humans; Nitriles; Pneumonia; Pyridines; Risk Factors; Triazoles; Voriconazole | 2015 |
Isavuconazole: Pharmacology, Pharmacodynamics, and Current Clinical Experience with a New Triazole Antifungal Agent.
Topics: Antifungal Agents; Aspergillosis; Candidemia; Candidiasis, Invasive; Humans; Mucormycosis; Nitriles; Pyridines; Triazoles | 2015 |
Dosing of antifungal agents in obese people.
Topics: Amphotericin B; Antifungal Agents; Candidiasis, Invasive; Caspofungin; Echinocandins; Fluconazole; Humans; Lipopeptides; Micafungin; Mycoses; Nitriles; Obesity; Pyridines; Triazoles | 2016 |
Isavuconazonium sulfate for the treatment of fungal infection.
Topics: Antifungal Agents; Clinical Trials as Topic; Drug Interactions; Humans; Mycoses; Nitriles; Pyridines; Triazoles | 2016 |
Isavuconazonium sulfate (Cresemba)--a new antifungal.
Topics: Antifungal Agents; Aspergillosis; Drug Interactions; Female; Fungi; Humans; Male; Mucormycosis; Mycoses; Nitriles; Pregnancy; Pyridines; Triazoles | 2016 |
Isavuconazonium sulfate: a new agent for the treatment of invasive aspergillosis and invasive mucormycosis.
Topics: Animals; Antifungal Agents; Aspergillosis; Humans; Invasive Fungal Infections; Mucormycosis; Nitriles; Pyridines; Triazoles | 2016 |
Treatment of mucormycosis in transplant patients: role of surgery and of old and new antifungal agents.
Topics: Amphotericin B; Antifungal Agents; DNA, Fungal; Humans; Mucorales; Mucormycosis; Nitriles; Opportunistic Infections; Pyridines; Salvage Therapy; Transplant Recipients; Triazoles | 2016 |
Breaking the Mold: A Review of Mucormycosis and Current Pharmacological Treatment Options.
Topics: Amphotericin B; Anidulafungin; Antifungal Agents; Caspofungin; Debridement; Drug Resistance, Fungal; Echinocandins; Humans; Lipopeptides; Male; Micafungin; Middle Aged; Mucorales; Mucormycosis; Nitriles; Pyridines; Triazoles; Virulence | 2016 |
Isavuconazonium sulfate: a triazole prodrug for invasive fungal infections.
Topics: Antifungal Agents; Humans; Invasive Fungal Infections; Nitriles; Prodrugs; Pyridines; Triazoles | 2017 |
Isavuconazole: A Review in Invasive Aspergillosis and Mucormycosis.
Topics: Animals; Antifungal Agents; Aspergillosis; Case-Control Studies; Clinical Trials, Phase III as Topic; Humans; Mucormycosis; Nitriles; Pyridines; Triazoles | 2016 |
Phellinus species: An emerging cause of refractory fungal infections in patients with X-linked chronic granulomatous disease.
Topics: Adolescent; Adult; Amphotericin B; Antifungal Agents; Basidiomycota; Brain; DNA, Ribosomal Spacer; Granulomatous Disease, Chronic; Hematopoietic Stem Cell Transplantation; Humans; Invasive Fungal Infections; Lung; Male; Nitriles; Pyridines; Tomography, X-Ray Computed; Triazoles; Young Adult | 2017 |
An update on the safety and interactions of antifungal drugs in stem cell transplant recipients.
Topics: Amphotericin B; Antifungal Agents; Dose-Response Relationship, Drug; Drug Interactions; Hematopoietic Stem Cell Transplantation; Humans; Invasive Fungal Infections; Nitriles; Pyridines; Triazoles | 2017 |
Therapeutic drug monitoring for invasive mould infections and disease: pharmacokinetic and pharmacodynamic considerations.
Topics: Antifungal Agents; Biological Availability; Drug Monitoring; Fungi; Humans; Invasive Fungal Infections; Itraconazole; Nitriles; Pyridines; Triazoles; Voriconazole | 2017 |
Invasive mould infections in the ICU setting: complexities and solutions.
Topics: Antifungal Agents; Aspergillosis; Aspergillus; beta-Glucans; Critical Illness; Galactose; Humans; Immunocompromised Host; Intensive Care Units; Invasive Fungal Infections; Lung Diseases, Fungal; Mannans; Mucor; Mucormycosis; Nitriles; Opportunistic Infections; Pyridines; Respiratory System; Triazoles; Voriconazole | 2017 |
Drug development challenges and strategies to address emerging and resistant fungal pathogens.
Topics: Antifungal Agents; Biomarkers; Candida; Candidiasis; Clinical Trials as Topic; Drug Design; Drug Resistance, Fungal; Echinocandins; Glycosides; Humans; Invasive Fungal Infections; Microbial Sensitivity Tests; Nitriles; Pyridines; Triazoles; Triterpenes | 2017 |
Special considerations for the diagnosis and treatment of invasive pulmonary aspergillosis.
Topics: Antifungal Agents; Humans; Immunocompromised Host; Invasive Pulmonary Aspergillosis; Multiplex Polymerase Chain Reaction; Nitriles; Pyridines; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Treatment Outcome; Triazoles | 2017 |
Graded isavuconazole introduction in a patient with voriconazole allergy.
Topics: Amphotericin B; Angioedema; Antifungal Agents; Aspergillus; Desensitization, Immunologic; Drug Administration Schedule; Drug Hypersensitivity; Female; Humans; Liver Cirrhosis; Liver Transplantation; Lung; Middle Aged; Nitriles; Pulmonary Aspergillosis; Pyridines; Tomography, X-Ray Computed; Treatment Outcome; Triazoles; Voriconazole | 2017 |
A Review of the Clinical Pharmacokinetics and Pharmacodynamics of Isavuconazole.
Topics: Antifungal Agents; Biological Availability; Drug Monitoring; Humans; Mucormycosis; Nitriles; Pyridines; Triazoles | 2018 |
Isavuconazole: A new broad-spectrum azole. Part 2: pharmacokinetics and clinical activity.
Topics: Animals; Antifungal Agents; Aspergillosis; Azoles; Candidemia; Clinical Trials as Topic; Double-Blind Method; Drug Evaluation, Preclinical; Esterases; Humans; Invasive Fungal Infections; Mice; Mucormycosis; Nitriles; Pyridines; Triazoles | 2018 |
Isavuconazole treatment for rare fungal diseases and for invasive aspergillosis in patients with renal impairment: Challenges and lessons of the VITAL trial.
Topics: Adult; Antifungal Agents; Fungi; Humans; Immunocompromised Host; Invasive Fungal Infections; Invasive Pulmonary Aspergillosis; Middle Aged; Mucormycosis; Mycoses; Nitriles; Pyridines; Randomized Controlled Trials as Topic; Rare Diseases; Renal Insufficiency; Triazoles | 2018 |
Clinical Pharmacokinetics and Pharmacodynamics of Isavuconazole.
Topics: Adult; Animals; Antifungal Agents; Aspergillosis; Drug Interactions; Humans; Invasive Fungal Infections; Mucormycosis; Nitriles; Pyridines; Triazoles | 2018 |
Spotlight on isavuconazole in the treatment of invasive aspergillosis and mucormycosis: design, development, and place in therapy.
Topics: Animals; Antifungal Agents; Aspergillosis; Drug Design; Humans; Mucormycosis; Nitriles; Pyridines; Triazoles | 2018 |
Systematic review and network meta-analysis of clinical outcomes associated with isavuconazole versus relevant comparators for patients with invasive aspergillosis.
Topics: Amphotericin B; Antifungal Agents; Aspergillosis; Deoxycholic Acid; Drug Combinations; Humans; Network Meta-Analysis; Nitriles; Pyridines; Randomized Controlled Trials as Topic; Treatment Outcome; Triazoles; Voriconazole | 2018 |
Isavuconazole in a Successful Combination Treatment of Disseminated Mucormycosis in a Child with Acute Lymphoblastic Leukaemia and Generalized Haemochromatosis: A Case Report and Review of the Literature.
Topics: Amphotericin B; Antifungal Agents; Caspofungin; Child; Cunninghamella; Debridement; Drug Therapy, Combination; Drug-Related Side Effects and Adverse Reactions; Female; Hemochromatosis; Humans; Invasive Fungal Infections; Mucormycosis; Nitriles; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Pyridines; Treatment Outcome; Triazoles | 2019 |
The spectrum of pulmonary aspergillosis.
Topics: Antifungal Agents; Aspergillosis, Allergic Bronchopulmonary; Aspergillus; Environmental Exposure; Fungi; Humans; Invasive Pulmonary Aspergillosis; Nitriles; Prognosis; Pulmonary Aspergillosis; Pyridines; Recurrence; Triazoles | 2018 |
Therapeutic tools for oral candidiasis: Current and new antifungal drugs.
Topics: Administration, Intravenous; Administration, Oral; Administration, Topical; Amphotericin B; Anidulafungin; Antifungal Agents; Azoles; Candidiasis, Oral; Caspofungin; Clotrimazole; Databases, Factual; Drug Interactions; Echinocandins; Fluconazole; Humans; Miconazole; Nitriles; Nystatin; Pyridines; Triazoles | 2019 |
A Case Series and Literature Review of Isavuconazole Use in Pediatric Patients with Hemato-oncologic Diseases and Hematopoietic Stem Cell Transplantation.
Topics: Administration, Intravenous; Administration, Oral; Adolescent; Antifungal Agents; Aspergillus; Child; Child, Preschool; Drug Administration Schedule; Female; Hematologic Neoplasms; Hematopoietic Stem Cell Transplantation; Humans; Invasive Fungal Infections; Male; Microbial Sensitivity Tests; Mucor; Nitriles; Penicillium; Pyridines; Retrospective Studies; Transplantation, Homologous; Triazoles | 2020 |
An overview of the available treatments for chronic cavitary pulmonary aspergillosis.
Topics: Amphotericin B; Antifungal Agents; Aspergillus fumigatus; Disease Management; Echinocandins; Humans; Itraconazole; Nitriles; Practice Guidelines as Topic; Pulmonary Aspergillosis; Pyridines; Triazoles; Voriconazole | 2020 |
Antifungal therapeutic drug monitoring: focus on drugs without a clear recommendation.
Topics: Antifungal Agents; Drug Monitoring; Echinocandins; Fluconazole; Humans; Mycoses; Nitriles; Polyenes; Practice Guidelines as Topic; Pyridines; Triazoles | 2020 |
Conidiobolus pachyzygosporus invasive pulmonary infection in a patient with acute myeloid leukemia: case report and review of the literature.
Topics: Aged; Antifungal Agents; Biopsy; Conidiobolus; DNA, Fungal; DNA, Ribosomal; Female; Humans; Hyphae; Immunocompromised Host; Leukemia, Myeloid, Acute; Lung Diseases, Fungal; Nitriles; Pyridines; Switzerland; Tomography, X-Ray Computed; Treatment Outcome; Triazoles; Zygomycosis | 2020 |
Invasive pulmonary aspergillosis associated with COVID-19 in a kidney transplant recipient.
Topics: Acute Kidney Injury; Administration, Inhalation; Amphotericin B; Anti-Bacterial Agents; Antibodies, Monoclonal, Humanized; Antifungal Agents; Azithromycin; Ceftriaxone; COVID-19; Deprescriptions; Female; Glucocorticoids; Graft Rejection; Humans; Hydroxychloroquine; Hyperoxaluria, Primary; Immunoglobulins, Intravenous; Immunologic Factors; Immunosuppressive Agents; Invasive Pulmonary Aspergillosis; Kidney Failure, Chronic; Kidney Transplantation; Middle Aged; Mycophenolic Acid; Nitriles; Oxygen Inhalation Therapy; Prednisone; Pyridines; Renal Dialysis; SARS-CoV-2; Sputum; Tacrolimus; Tomography, X-Ray Computed; Triazoles | 2021 |
Defining and managing COVID-19-associated pulmonary aspergillosis: the 2020 ECMM/ISHAM consensus criteria for research and clinical guidance.
Topics: Amphotericin B; Antifungal Agents; Azoles; Coinfection; COVID-19; Humans; Nitriles; Pulmonary Aspergillosis; Pyridines; SARS-CoV-2; Triazoles; Voriconazole | 2021 |
Pulmonary infection secondary to Blastobotrys raffinosifermentans in a cystic fibrosis patient: Review of the literature.
Topics: Adult; Amphotericin B; Antifungal Agents; Cystic Fibrosis; Female; Fluconazole; Genes, Fungal; Humans; Immunosuppression Therapy; Microbial Sensitivity Tests; Mycoses; Nitriles; Phylogeny; Pneumonia; Pyridines; Saccharomycetales; Triazoles | 2021 |
A minireview of 1,2,3-triazole hybrids with O-heterocycles as leads in medicinal chemistry.
Topics: Azides; Chemistry, Pharmaceutical; Cycloaddition Reaction; Drug Design; Molecular Structure; Structure-Activity Relationship; Triazoles | 2022 |
Isavuconazole and Liposomal Amphotericin B as Successful Combination Therapy of Refractory Invasive Candidiasis in a Liver Transplant Recipient: A Case Report and Literature Review.
Topics: Amphotericin B; Antifungal Agents; Candidiasis, Invasive; Humans; Liver Transplantation; Nitriles; Pyridines; Triazoles | 2022 |
Effectiveness and safety of isavuconazole prophylaxis for invasive fungal infections in the haematologic setting.
Topics: Adult; Antifungal Agents; Humans; Invasive Fungal Infections; Nitriles; Pyridines; Triazoles | 2022 |
Plain language summary: use of isavuconazole in Chinese patients with an invasive fungal disease.
Topics: Antifungal Agents; Aspergillosis; Drug-Related Side Effects and Adverse Reactions; Healthy Volunteers; Humans; Invasive Fungal Infections; Mycoses; Nitriles; Pyridines; Triazoles; Voriconazole | 2022 |
New Perspectives on Antimicrobial Agents: Isavuconazole.
Topics: Antifungal Agents; Candidiasis, Invasive; Caspofungin; Fungi; Humans; Invasive Fungal Infections; Nitriles; Pyridines; Triazoles; Voriconazole | 2022 |
Clinical research advances of isavuconazole in the treatment of invasive fungal diseases.
Topics: Antifungal Agents; Aspergillosis; Candidiasis, Invasive; Humans; Invasive Fungal Infections; Mucormycosis; Nitriles; Triazoles | 2022 |
A systematic review and meta-analysis of efficacy and safety of isavuconazole for the treatment and prophylaxis of invasive fungal infections.
Topics: Antifungal Agents; Humans; Invasive Fungal Infections; Triazoles; Voriconazole | 2023 |
37 trial(s) available for triazoles and isavuconazole
| Article | Year |
|---|---|
Single-ascending-dose pharmacokinetics and safety of the novel broad-spectrum antifungal triazole BAL4815 after intravenous infusions (50, 100, and 200 milligrams) and oral administrations (100, 200, and 400 milligrams) of its prodrug, BAL8557, in healthy
Topics: Administration, Oral; Adult; Antifungal Agents; Biological Availability; Cohort Studies; Dose-Response Relationship, Drug; Double-Blind Method; Fungi; Half-Life; Healthy Volunteers; Humans; Infusions, Intravenous; Male; Middle Aged; Nitriles; Prodrugs; Pyridines; Safety; Triazoles | 2006 |
Multiple-dose pharmacokinetics and safety of the new antifungal triazole BAL4815 after intravenous infusion and oral administration of its prodrug, BAL8557, in healthy volunteers.
Topics: Administration, Oral; Antifungal Agents; Biological Availability; Cohort Studies; Double-Blind Method; Fungi; Half-Life; Healthy Volunteers; Humans; Infusions, Intravenous; Male; Nitriles; Prodrugs; Pyridines; Safety; Triazoles | 2006 |
Effect of mild and moderate liver disease on the pharmacokinetics of isavuconazole after intravenous and oral administration of a single dose of the prodrug BAL8557.
Topics: Administration, Oral; Antifungal Agents; Area Under Curve; Female; Humans; Injections, Intravenous; Liver Diseases; Male; Middle Aged; Nitriles; Prodrugs; Pyridines; Triazoles | 2009 |
A phase 2, randomized, double-blind, multicenter trial to evaluate the safety and efficacy of three dosing regimens of isavuconazole compared with fluconazole in patients with uncomplicated esophageal candidiasis.
Topics: Administration, Oral; Adult; Antifungal Agents; Candidiasis; Double-Blind Method; Esophageal Diseases; Female; Fluconazole; Humans; Male; Nitriles; Pyridines; Triazoles | 2015 |
Safety and pharmacokinetics of isavuconazole as antifungal prophylaxis in acute myeloid leukemia patients with neutropenia: results of a phase 2, dose escalation study.
Topics: Adult; Aged; Antifungal Agents; Cohort Studies; Dose-Response Relationship, Drug; Female; Humans; Immunosuppression Therapy; Leukemia, Myeloid, Acute; Male; Middle Aged; Mycoses; Neutropenia; Nitriles; Patient Safety; Pyridines; Triazoles | 2015 |
Isavuconazole versus voriconazole for primary treatment of invasive mould disease caused by Aspergillus and other filamentous fungi (SECURE): a phase 3, randomised-controlled, non-inferiority trial.
Topics: Administration, Oral; Adult; Aged; Antifungal Agents; Aspergillosis; Double-Blind Method; Drug Administration Schedule; Female; Humans; Injections, Intravenous; Male; Middle Aged; Mycoses; Nitriles; Pyridines; Treatment Outcome; Triazoles; Voriconazole | 2016 |
Population Pharmacokinetics of Isavuconazole in Subjects with Mild or Moderate Hepatic Impairment.
Topics: Administration, Oral; Female; Healthy Volunteers; Humans; Liver; Liver Diseases; Male; Models, Theoretical; Nitriles; Pyridines; Triazoles | 2016 |
Hospital resource use of patients receiving isavuconazole vs voriconazole for invasive mold infections in the phase III SECURE trial.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antifungal Agents; Aspergillosis; Body Mass Index; Double-Blind Method; Female; Glomerular Filtration Rate; Hospital Charges; Humans; Kaplan-Meier Estimate; Length of Stay; Male; Middle Aged; Mycoses; Nitriles; Pyridines; Triazoles; Voriconazole; Young Adult | 2016 |
Isavuconazole treatment for mucormycosis: a single-arm open-label trial and case-control analysis.
Topics: Administration, Intravenous; Adult; Animals; Antifungal Agents; Aspergillosis; Female; Fungi; Humans; Male; Middle Aged; Mucormycosis; Nitriles; Pyridines; Treatment Outcome; Triazoles | 2016 |
Pharmacodynamics of isavuconazole in experimental invasive pulmonary aspergillosis: implications for clinical breakpoints.
Topics: Animals; Antifungal Agents; Aspergillus; Disease Models, Animal; Drug Monitoring; Female; Galactose; Humans; Invasive Pulmonary Aspergillosis; Mannans; Microbial Sensitivity Tests; Models, Theoretical; Monte Carlo Method; Nitriles; Pyridines; Rabbits; Triazoles | 2016 |
Isavuconazole Treatment of Cryptococcosis and Dimorphic Mycoses.
Topics: Adult; Aged; Antifungal Agents; Blastomycosis; Coccidioidomycosis; Cryptococcosis; Female; Histoplasmosis; Humans; Male; Middle Aged; Mycoses; Nitriles; Paracoccidioidomycosis; Pyridines; Triazoles; Young Adult | 2016 |
Pharmacokinetic Interactions Between Isavuconazole and the Drug Transporter Substrates Atorvastatin, Digoxin, Metformin, and Methotrexate in Healthy Subjects.
Topics: Adult; Area Under Curve; Atorvastatin; Digoxin; Female; Healthy Volunteers; Humans; Male; Membrane Transport Proteins; Metformin; Methotrexate; Middle Aged; Nitriles; Pyridines; Triazoles; Young Adult | 2017 |
Pharmacokinetic Effects of Isavuconazole Coadministration With the Cytochrome P450 Enzyme Substrates Bupropion, Repaglinide, Caffeine, Dextromethorphan, and Methadone in Healthy Subjects.
Topics: Adult; Area Under Curve; Bupropion; Caffeine; Carbamates; Cytochrome P-450 Enzyme System; Dextromethorphan; Drug Interactions; Female; Healthy Volunteers; Humans; Male; Methadone; Middle Aged; Nitriles; Piperidines; Pyridines; Triazoles; Young Adult | 2017 |
Pharmacokinetic Assessment of Drug-Drug Interactions of Isavuconazole With the Immunosuppressants Cyclosporine, Mycophenolic Acid, Prednisolone, Sirolimus, and Tacrolimus in Healthy Adults.
Topics: Adult; Area Under Curve; Cyclosporine; Drug Interactions; Female; Healthy Volunteers; Humans; Male; Middle Aged; Mycophenolic Acid; Nitriles; Prednisolone; Pyridines; Sirolimus; Tacrolimus; Triazoles; Young Adult | 2017 |
Pharmacokinetic and Pharmacodynamic Evaluation of the Drug-Drug Interaction Between Isavuconazole and Warfarin in Healthy Subjects.
Topics: Adult; Area Under Curve; Drug Administration Schedule; Drug Interactions; Female; Healthy Volunteers; Humans; International Normalized Ratio; Male; Middle Aged; Nitriles; Prothrombin Time; Pyridines; Triazoles; Warfarin; Young Adult | 2017 |
Isavuconazole absorption following oral administration in healthy subjects is comparable to intravenous dosing, and is not affected by food, or drugs that alter stomach pH.
Topics: Administration, Intravenous; Administration, Oral; Adult; Biological Availability; Cross-Over Studies; Drug Interactions; Female; Food-Drug Interactions; Humans; Hydrogen-Ion Concentration; Male; Middle Aged; Nitriles; Pyridines; Stomach; Triazoles | 2016 |
Population Pharmacokinetics of Isavuconazole from Phase 1 and Phase 3 (SECURE) Trials in Adults and Target Attainment in Patients with Invasive Infections Due to Aspergillus and Other Filamentous Fungi.
Topics: Antifungal Agents; Area Under Curve; Aspergillosis; Aspergillus; Fungi; Humans; Microbial Sensitivity Tests; Monte Carlo Method; Nitriles; Probability; Pyridines; Triazoles | 2016 |
Cost-Effectiveness Analysis of Isavuconazole vs. Voriconazole as First-Line Treatment for Invasive Aspergillosis.
Topics: Antifungal Agents; Aspergillosis; Cost-Benefit Analysis; Fees, Pharmaceutical; Female; Hospitalization; Humans; Male; Models, Econometric; Nitriles; Pyridines; Triazoles; Voriconazole | 2017 |
QT Interval Shortening With Isavuconazole: In Vitro and In Vivo Effects on Cardiac Repolarization.
Topics: Action Potentials; Adult; Antifungal Agents; Arrhythmias, Cardiac; Calcium Channel Blockers; Calcium Channels, L-Type; Cell Line; Dose-Response Relationship, Drug; Double-Blind Method; Electrocardiography; Female; Heart Conduction System; Heart Rate; Humans; Male; Models, Biological; Nitriles; Pyridines; Risk Assessment; Time Factors; Transfection; Triazoles; Young Adult | 2017 |
Impact of Mucositis on Absorption and Systemic Drug Exposure of Isavuconazole.
Topics: Adolescent; Adult; Aged; Antifungal Agents; Aspergillosis; Biological Availability; Female; Humans; Invasive Fungal Infections; Male; Middle Aged; Mucormycosis; Mucositis; Nitriles; Pyridines; Treatment Outcome; Triazoles; Young Adult | 2017 |
Pharmacodynamics of Isavuconazole for Invasive Mold Disease: Role of Galactomannan for Real-Time Monitoring of Therapeutic Response.
Topics: Adult; Aged; Biomarkers; Drug Monitoring; Female; Galactose; Humans; Invasive Fungal Infections; Invasive Pulmonary Aspergillosis; Logistic Models; Male; Mannans; Middle Aged; Nitriles; Proportional Hazards Models; Pyridines; Survival Analysis; Treatment Outcome; Triazoles | 2017 |
Two Phase 1, Open-Label, Mass Balance Studies to Determine the Pharmacokinetics of
Topics: Adolescent; Adult; Antifungal Agents; Biological Availability; Carbon Radioisotopes; Healthy Volunteers; Humans; Male; Metabolome; Middle Aged; Nitriles; Prodrugs; Pyridines; Triazoles; Young Adult | 2018 |
Exposure-Response Relationships for Isavuconazole in Patients with Invasive Aspergillosis and Other Filamentous Fungi.
Topics: Alanine Transaminase; Antifungal Agents; Aspartate Aminotransferases; Aspergillosis; Dose-Response Relationship, Drug; Drug Monitoring; Humans; Invasive Fungal Infections; Nitriles; Pyridines; Triazoles | 2017 |
Impact of unresolved neutropenia in patients with neutropenia and invasive aspergillosis: a post hoc analysis of the SECURE trial.
Topics: Adult; Aged; Antifungal Agents; Aspergillus; Female; Humans; Invasive Pulmonary Aspergillosis; Male; Middle Aged; Neutropenia; Nitriles; Pyridines; Treatment Outcome; Triazoles; Voriconazole | 2018 |
Isavuconazole for treatment of invasive fungal diseases caused by more than one fungal species.
Topics: Administration, Intravenous; Adult; Aged; Antifungal Agents; Aspergillosis; Aspergillus; Coinfection; Drug-Related Side Effects and Adverse Reactions; Female; Humans; Invasive Fungal Infections; Male; Middle Aged; Mucorales; Mucormycosis; Nitriles; Pyridines; Treatment Outcome; Triazoles | 2018 |
Isavuconazole for treatment of rare invasive fungal diseases.
Topics: Administration, Intravenous; Administration, Oral; Adult; Aged; Aged, 80 and over; Antifungal Agents; Drug-Related Side Effects and Adverse Reactions; Female; Humans; Invasive Fungal Infections; Male; Middle Aged; Nitriles; Pyridines; Survival Analysis; Treatment Outcome; Triazoles; Young Adult | 2018 |
Development and Validation of a Chromatographic Ultraviolet Method for the Quantification of Isavuconazole in Human Plasma Samples.
Topics: Antifungal Agents; Chromatography, High Pressure Liquid; Drug Monitoring; Healthy Volunteers; Humans; Nitriles; Pyridines; Spectrophotometry, Ultraviolet; Triazoles | 2018 |
Treatment outcomes in patients with proven/probable vs possible invasive mould disease in a phase III trial comparing isavuconazole vs voriconazole.
Topics: Adult; Aged; Antifungal Agents; Female; Fungi; Humans; Invasive Fungal Infections; Male; Middle Aged; Nitriles; Pyridines; Treatment Outcome; Triazoles; Voriconazole | 2018 |
Isavuconazole Versus Caspofungin in the Treatment of Candidemia and Other Invasive Candida Infections: The ACTIVE Trial.
Topics: Adult; Aged; Candida; Candidemia; Candidiasis, Invasive; Caspofungin; Female; Humans; Male; Middle Aged; Nitriles; Pyridines; Treatment Outcome; Triazoles | 2019 |
Outcomes by MIC Values for Patients Treated with Isavuconazole or Voriconazole for Invasive Aspergillosis in the Phase 3 SECURE and VITAL Trials.
Topics: Antifungal Agents; Aspergillosis; Aspergillus; Humans; Invasive Fungal Infections; Microbial Sensitivity Tests; Nitriles; Pyridines; Triazoles; Voriconazole | 2019 |
Variability and exposure-response relationships of isavuconazole plasma concentrations in the Phase 3 SECURE trial of patients with invasive mould diseases.
Topics: Antifungal Agents; Aspergillosis; Aspergillus; Drug Monitoring; Female; Humans; Invasive Fungal Infections; Male; Nitriles; Pyridines; Treatment Outcome; Triazoles | 2019 |
Isavuconazole as Primary Antifungal Prophylaxis in Patients With Acute Myeloid Leukemia or Myelodysplastic Syndrome: An Open-label, Prospective, Phase 2 Study.
Topics: Adult; Aged; Antifungal Agents; Humans; Leukemia, Myeloid, Acute; Mycoses; Myelodysplastic Syndromes; Nitriles; Prospective Studies; Pyridines; Triazoles | 2021 |
Clinical experience with isavuconazole in healthy volunteers and patients with invasive aspergillosis in China, and the results from an exposure-response analysis.
Topics: Administration, Intravenous; Administration, Oral; Antifungal Agents; Asian People; Aspergillosis; China; Healthy Volunteers; Human Experimentation; Humans; Invasive Fungal Infections; Nitriles; Pyridines; Treatment Outcome; Triazoles | 2021 |
Isavuconazole Treatment of Invasive Fungal Sinusitis: A Post Hoc Analysis of the SECURE and VITAL Trials.
Topics: Antifungal Agents; Aspergillosis; Humans; Invasive Fungal Infections; Mucormycosis; Nitriles; Pyridines; Sinusitis; Triazoles | 2021 |
Pharmacokinetics and Bioequivalence of Isavuconazole Administered as Isavuconazonium Sulfate Intravenous Solution via Nasogastric Tube or Orally in Healthy Subjects.
Topics: Area Under Curve; Cross-Over Studies; Female; Healthy Volunteers; Humans; Male; Nitriles; Pyridines; Tablets; Therapeutic Equivalency; Triazoles | 2021 |
Pharmacokinetics, Safety, and Tolerability of Single and Multiple Doses of Isavuconazonium Sulfate in Healthy Adult Japanese Subjects.
Topics: Adult; Humans; Japan; Nitriles; Pyridines; Triazoles | 2022 |
Efficacy and safety of isavuconazole against deep-seated mycoses: A phase 3, randomized, open-label study in Japan.
Topics: Antifungal Agents; Aspergillosis; Cryptococcosis; Humans; Invasive Fungal Infections; Japan; Mucormycosis; Pulmonary Aspergillosis; Triazoles; Voriconazole | 2023 |
249 other study(ies) available for triazoles and isavuconazole
| Article | Year |
|---|---|
In vitro activity of a new triazole BAL4815, the active component of BAL8557 (the water-soluble prodrug), against Aspergillus spp.
Topics: Antifungal Agents; Aspergillus; Drug Resistance, Fungal; Microbial Sensitivity Tests; Molecular Structure; Nitriles; Prodrugs; Pyridines; Solubility; Triazoles; Water | 2006 |
Investigation of low-abundant in vitro metabolites of stable isotope-labelled BAL4815 by accurate mass capillary-LC-ESI-qTof-MS and MS/MS.
Topics: Animals; Antifungal Agents; Capillary Action; Chromatography, Liquid; Deuterium; Hepatocytes; Isotope Labeling; Male; Mass Spectrometry; Models, Molecular; Nitriles; Rats; Rats, Wistar; Spectrometry, Mass, Electrospray Ionization; Triazoles | 2006 |
Comparative in vivo activity of BAL4815, the active component of the prodrug BAL8557, in a neutropenic murine model of disseminated Aspergillus flavus.
Topics: Animals; Antifungal Agents; Aspergillosis; Aspergillus flavus; Brain; Caspofungin; Colony Count, Microbial; Disease Models, Animal; Echinocandins; Fluorescence Resonance Energy Transfer; Immunocompromised Host; Immunosuppression Therapy; Itraconazole; Kidney; Lipopeptides; Liver; Lung; Male; Mice; Neutropenia; Nitriles; Peptides, Cyclic; Polymerase Chain Reaction; Pyrimidines; Survival Analysis; Triazoles; Voriconazole | 2006 |
In vitro activities of isavuconazole and other antifungal agents against Candida bloodstream isolates.
Topics: Antifungal Agents; Area Under Curve; Candida; Fungemia; Humans; Microbial Sensitivity Tests; Nitriles; Pyridines; Triazoles | 2007 |
In Vitro activity of the new azole isavuconazole (BAL4815) compared with six other antifungal agents against 162 Cryptococcus neoformans isolates from Cuba.
Topics: Antifungal Agents; Azoles; Cryptococcosis; Cryptococcus neoformans; Cuba; Humans; Microbial Sensitivity Tests; Nitriles; Pyridines; Triazoles | 2008 |
In vitro antifungal activities of isavuconazole (BAL4815), voriconazole, and fluconazole against 1,007 isolates of zygomycete, Candida, Aspergillus, Fusarium, and Scedosporium species.
Topics: Antifungal Agents; Aspergillus; Candida; Fluconazole; Fungi; Fusarium; Humans; Microbial Sensitivity Tests; Mycoses; Nitriles; Opportunistic Infections; Pyrimidines; Scedosporium; Triazoles; Voriconazole | 2008 |
Activity of BAL 4815 against filamentous fungi.
Topics: Antifungal Agents; Fungi; Microbial Sensitivity Tests; Nitriles; Triazoles | 2008 |
Evaluation of Etest method for determining isavuconazole MICs against Cryptococcus gattii and Cryptococcus neoformans.
Topics: Antifungal Agents; Cryptococcus; Cryptococcus neoformans; Microbial Sensitivity Tests; Nitriles; Pyridines; Reproducibility of Results; Species Specificity; Triazoles | 2008 |
Antifungal susceptibilities among different serotypes of Cryptococcus gattii and Cryptococcus neoformans.
Topics: Antifungal Agents; Cryptococcus; Cryptococcus neoformans; Fluconazole; Microbial Sensitivity Tests; Nitriles; Pyridines; Pyrimidines; Serotyping; Triazoles; Voriconazole | 2009 |
Efficacy of isavuconazole, voriconazole and fluconazole in temporarily neutropenic murine models of disseminated Candida tropicalis and Candida krusei.
Topics: Animals; Antifungal Agents; Brain; Candidiasis; Colony Count, Microbial; Dose-Response Relationship, Drug; Fluconazole; Kidney; Male; Mice; Neutropenia; Nitriles; Pyridines; Pyrimidines; Treatment Outcome; Triazoles; Voriconazole | 2009 |
In vitro activities of isavuconazole against opportunistic filamentous and dimorphic fungi.
Topics: Amphotericin B; Antifungal Agents; Fungi; Humans; Microbial Sensitivity Tests; Mycoses; Nitriles; Opportunistic Infections; Pyridines; Triazoles | 2009 |
In vitro activity of Isavuconazole against Aspergillus species and zygomycetes according to the methodology of the European Committee on Antimicrobial Susceptibility Testing.
Topics: Antifungal Agents; Aspergillus; Microbial Sensitivity Tests; Mucorales; Nitriles; Pyridines; Triazoles | 2009 |
In vitro activity of isavuconazole against Trichosporon, Rhodotorula, Geotrichum, Saccharomyces and Pichia species.
Topics: Antifungal Agents; Fungi; Humans; Microbial Sensitivity Tests; Mycoses; Nitriles; Pyridines; Triazoles | 2009 |
Pharmacokinetics and pharmacodynamics of a novel triazole, isavuconazole: mathematical modeling, importance of tissue concentrations, and impact of immune status on antifungal effect.
Topics: Animals; Antifungal Agents; Candidiasis; Kidney; Male; Mice; Models, Theoretical; Nitriles; Proportional Hazards Models; Pyridines; Triazoles | 2009 |
In vitro antifungal activity of isavuconazole against 345 mucorales isolates collected at study centers in eight countries.
Topics: Antifungal Agents; Guidelines as Topic; Humans; Microbial Sensitivity Tests; Mucorales; Nitriles; Pyridines; Triazoles | 2009 |
In vitro activities of eight antifungal drugs against 55 clinical isolates of Fonsecaea spp.
Topics: Amphotericin B; Anidulafungin; Antifungal Agents; Ascomycota; Caspofungin; Chromoblastomycosis; Drug Resistance, Fungal; Echinocandins; Fluconazole; Humans; In Vitro Techniques; Itraconazole; Lipopeptides; Microbial Sensitivity Tests; Nitriles; Pyridines; Pyrimidines; Triazoles; Voriconazole | 2010 |
In vitro antifungal activities of isavuconazole and comparators against rare yeast pathogens.
Topics: Antifungal Agents; Dipodascus; Fluconazole; Microbial Sensitivity Tests; Nitriles; Pyridines; Pyrimidines; Rhodotorula; Saccharomyces cerevisiae; Triazoles; Trichosporon; Voriconazole | 2010 |
In vitro activity of isavuconazole against 140 reference fungal strains and 165 clinically isolated yeasts from Japan.
Topics: Amphotericin B; Antifungal Agents; Azoles; Fungi; Humans; Japan; Microbial Sensitivity Tests; Mycoses; Nitriles; Pyridines; Reference Standards; Triazoles; Yeasts | 2010 |
In vitro antifungal susceptibilities and amplified fragment length polymorphism genotyping of a worldwide collection of 350 clinical, veterinary, and environmental Cryptococcus gattii isolates.
Topics: Amphotericin B; Amplified Fragment Length Polymorphism Analysis; Animals; Antifungal Agents; Cryptococcus gattii; Environmental Microbiology; Fluconazole; Flucytosine; Genotype; Humans; Microbial Sensitivity Tests; Nitriles; Pyridines; Pyrimidines; Triazoles; Voriconazole | 2010 |
In vitro susceptibility of 188 clinical and environmental isolates of Aspergillus flavus for the new triazole isavuconazole and seven other antifungal drugs.
Topics: Antifungal Agents; Aspergillosis; Aspergillus flavus; Environmental Microbiology; Humans; India; Microbial Sensitivity Tests; Netherlands; Nitriles; Pyridines; Triazoles | 2011 |
In vitro activity of isavuconazole against 208 Aspergillus flavus isolates in comparison with 7 other antifungal agents: assessment according to the methodology of the European Committee on Antimicrobial Susceptibility Testing.
Topics: Antifungal Agents; Aspergillosis; Aspergillus flavus; Humans; India; Microbial Sensitivity Tests; Netherlands; Nitriles; Pyridines; Triazoles | 2011 |
In vitro activities of nine antifungal drugs against 81 Phialophora and Cyphellophora isolates.
Topics: Amphotericin B; Antifungal Agents; Caspofungin; Echinocandins; Fluconazole; Itraconazole; Lipopeptides; Micafungin; Microbial Sensitivity Tests; Mitosporic Fungi; Naphthalenes; Nitriles; Phialophora; Pyridines; Pyrimidines; Terbinafine; Triazoles; Voriconazole | 2012 |
In vitro antifungal activity of isavuconazole against Madurella mycetomatis.
Topics: Antifungal Agents; Humans; Itraconazole; Ketoconazole; Madurella; Microbial Sensitivity Tests; Mycetoma; Nitriles; Pyridines; Triazoles | 2012 |
In vitro antifungal susceptibility of Cladophialophora carrionii, an agent of human chromoblastomycosis.
Topics: Amphotericin B; Antifungal Agents; Ascomycota; Caspofungin; Chromoblastomycosis; Echinocandins; Lipopeptides; Micafungin; Microbial Sensitivity Tests; Nitriles; Pyridines; Pyrimidines; Triazoles; Voriconazole | 2013 |
Candida nivariensis as an etiologic agent of vulvovaginal candidiasis in a tertiary care hospital of New Delhi, India.
Topics: Adult; Amphotericin B; Antifungal Agents; Candida; Candidiasis, Vulvovaginal; DNA, Fungal; Drug Resistance, Fungal; Echinocandins; Female; Fluconazole; Genotype; Humans; India; Itraconazole; Microbial Sensitivity Tests; Nitriles; Phenotype; Phylogeny; Polymerase Chain Reaction; Pyridines; Pyrimidines; Sequence Analysis, DNA; Tertiary Care Centers; Triazoles; Voriconazole; Young Adult | 2013 |
Multicenter study of isavuconazole MIC distributions and epidemiological cutoff values for Aspergillus spp. for the CLSI M38-A2 broth microdilution method.
Topics: Antifungal Agents; Aspergillosis; Aspergillus; Cytochrome P-450 Enzyme System; Drug Resistance, Fungal; Fungal Proteins; Genes, Fungal; Geography; Humans; Microbial Sensitivity Tests; Mutation; Nitriles; Pyridines; Pyrimidines; Reference Values; Triazoles; Voriconazole | 2013 |
In vitro activities of isavuconazole and comparator antifungal agents tested against a global collection of opportunistic yeasts and molds.
Topics: Antifungal Agents; Aspergillosis; Aspergillus; Candida; Candidiasis; Humans; Microbial Sensitivity Tests; Nitriles; Opportunistic Infections; Pyridines; Triazoles | 2013 |
Isavuconazole activity against Aspergillus lentulus, Neosartorya udagawae, and Cryptococcus gattii, emerging fungal pathogens with reduced azole susceptibility.
Topics: Antifungal Agents; Aspergillus; Azoles; Communicable Diseases, Emerging; Cryptococcus gattii; Humans; Microbial Sensitivity Tests; Mycoses; Neosartorya; Nitriles; North America; Pyridines; Triazoles | 2013 |
Head-to-head comparison of inhibitory and fungicidal activities of fluconazole, itraconazole, voriconazole, posaconazole, and isavuconazole against clinical isolates of Trichosporon asahii.
Topics: Antifungal Agents; Fluconazole; Itraconazole; Microbial Sensitivity Tests; Nitriles; Pyridines; Pyrimidines; Triazoles; Trichosporon; Voriconazole | 2013 |
Determination of isavuconazole susceptibility of Aspergillus and Candida species by the EUCAST method.
Topics: Antifungal Agents; Aspergillosis; Aspergillus; Candida; Candidiasis, Invasive; Drug Dosage Calculations; Drug Resistance, Fungal; Europe; Humans; Microbial Sensitivity Tests; Mutation; Nitriles; Pyridines; Triazoles | 2013 |
Isavuconazole pharmacodynamic target determination for Candida species in an in vivo murine disseminated candidiasis model.
Topics: Animals; Antifungal Agents; Area Under Curve; Candida albicans; Candida glabrata; Candida tropicalis; Candidiasis; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Administration Schedule; Female; Half-Life; Mice; Mice, Inbred ICR; Microbial Sensitivity Tests; Nitriles; Pyridines; Species Specificity; Triazoles | 2013 |
In vitro susceptibility of Aspergillus fumigatus to isavuconazole: correlation with itraconazole, voriconazole, and posaconazole.
Topics: Amino Acid Substitution; Amphotericin B; Antifungal Agents; Aspergillus fumigatus; Cytochrome P-450 Enzyme System; Drug Resistance, Fungal; Fungal Proteins; Humans; Itraconazole; Microbial Sensitivity Tests; Mutation; Nitriles; Pyridines; Pyrimidines; Triazoles; Voriconazole | 2013 |
In vitro activities of eight antifungal drugs against 106 waterborne and cutaneous exophiala species.
Topics: Amphotericin B; Antifungal Agents; Caspofungin; Echinocandins; Exophiala; Fluconazole; Itraconazole; Lipopeptides; Micafungin; Microbial Sensitivity Tests; Nitriles; Pyridines; Pyrimidines; Triazoles; Voriconazole | 2013 |
Isavuconazole (BAL4815) pharmacodynamic target determination in an in vivo murine model of invasive pulmonary aspergillosis against wild-type and cyp51 mutant isolates of Aspergillus fumigatus.
Topics: Animals; Antifungal Agents; Aspergillus fumigatus; Female; Invasive Pulmonary Aspergillosis; Mice; Mice, Inbred ICR; Nitriles; Pyridines; Triazoles | 2013 |
Successful isavuconazole salvage therapy in a patient with invasive mucormycosis.
Topics: Antifungal Agents; Brain Diseases; Humans; Male; Middle Aged; Mucormycosis; Nitriles; Pyridines; Rhizopus; Salvage Therapy; Treatment Outcome; Triazoles | 2014 |
Isavuconazole treatment of a patient with disseminated mucormycosis.
Topics: Antifungal Agents; Brain; Humans; Immunocompromised Host; Leukemia, Myeloid, Acute; Lung; Male; Middle Aged; Mucormycosis; Nitriles; Pyridines; Rhizomucor; Skin; Stem Cell Transplantation; Transplantation, Homologous; Treatment Outcome; Triazoles | 2014 |
Isavuconazole therapy protects immunosuppressed mice from mucormycosis.
Topics: Animals; Antifungal Agents; Immunosuppression Therapy; Male; Mice; Mice, Inbred ICR; Mucormycosis; Nitriles; Pyridines; Triazoles | 2014 |
Isavuconazole and nine comparator antifungal susceptibility profiles for common and uncommon Candida species collected in 2012: application of new CLSI clinical breakpoints and epidemiological cutoff values.
Topics: Antifungal Agents; Candida; Candidiasis; DNA, Fungal; DNA, Ribosomal; DNA, Ribosomal Spacer; Global Health; Humans; Microbial Sensitivity Tests; Nitriles; Pyridines; RNA, Ribosomal, 28S; Sequence Analysis, DNA; Triazoles | 2014 |
Pharmacokinetics of oral isavuconazole in a patient after Roux-en-Y gastric bypass surgery.
Topics: Administration, Oral; Antifungal Agents; Gastric Bypass; Humans; Lung Diseases, Fungal; Microbial Sensitivity Tests; Middle Aged; Mucormycosis; Nitriles; Pyridines; Rhizopus; Triazoles | 2014 |
EUCAST testing of Isavuconazole susceptibility in Aspergillus: comparison of results for Inoculum standardization using Conidium counting versus optical density.
Topics: Antifungal Agents; Aspergillosis; Aspergillus; Drug Resistance, Fungal; Microbial Sensitivity Tests; Nitriles; Pyridines; Spectrophotometry; Spores, Fungal; Triazoles | 2014 |
In vitro combination of isavuconazole with micafungin or amphotericin B deoxycholate against medically important molds.
Topics: Amphotericin B; Antifungal Agents; Aspergillosis; Aspergillus; Cunninghamella; Deoxycholic Acid; Drug Combinations; Drug Interactions; Echinocandins; Lipopeptides; Micafungin; Microbial Sensitivity Tests; Mucormycosis; Nitriles; Pyridines; Triazoles | 2014 |
Molecular characterization and in vitro antifungal susceptibility of 80 clinical isolates of mucormycetes in Delhi, India.
Topics: Amphotericin B; Amplified Fragment Length Polymorphism Analysis; Antifungal Agents; DNA, Fungal; Drug Resistance, Fungal; Humans; India; Itraconazole; Microbial Sensitivity Tests; Mucor; Mucorales; Mucormycosis; Mycological Typing Techniques; Nitriles; Pyridines; Rhizopus; Sequence Analysis, DNA; Specimen Handling; Triazoles | 2014 |
Multicenter study of isavuconazole MIC distributions and epidemiological cutoff values for the Cryptococcus neoformans-Cryptococcus gattii species complex using the CLSI M27-A3 broth microdilution method.
Topics: Antifungal Agents; Cryptococcosis; Cryptococcus gattii; Cryptococcus neoformans; Genotype; Humans; Microbial Sensitivity Tests; Nitriles; Pyridines; Triazoles | 2015 |
Pharmacodynamics of isavuconazole in an Aspergillus fumigatus mouse infection model.
Topics: Animals; Aspergillosis; Aspergillus fumigatus; Female; Mice; Nitriles; Pyridines; Triazoles | 2015 |
In vitro susceptibility patterns of clinically important Trichophyton and Epidermophyton species against nine antifungal drugs.
Topics: Amphotericin B; Anidulafungin; Antifungal Agents; Caspofungin; Echinocandins; Epidermophyton; Fluconazole; Humans; Itraconazole; Lipopeptides; Microbial Sensitivity Tests; Naphthalenes; Nitriles; Pyridines; Terbinafine; Tinea; Triazoles; Trichophyton; Voriconazole | 2015 |
Isavuconazonium sulfate approved for invasive fungal infections.
Topics: Administration, Oral; Antifungal Agents; Drug Approval; Humans; Infusions, Intravenous; Mycoses; Nitriles; Prodrugs; Pyridines; Triazoles | 2015 |
Isavuconazole, micafungin, and 8 comparator antifungal agents' susceptibility profiles for common and uncommon opportunistic fungi collected in 2013: temporal analysis of antifungal drug resistance using CLSI species-specific clinical breakpoints and prop
Topics: Antifungal Agents; Drug Resistance, Fungal; Echinocandins; Fungi; Global Health; Humans; Lipopeptides; Micafungin; Microbial Sensitivity Tests; Mycoses; Nitriles; Opportunistic Infections; Pyridines; Triazoles | 2015 |
Isavuconazole: a new extended spectrum triazole for invasive mold diseases.
Topics: Antifungal Agents; Double-Blind Method; Fungi; Humans; Mycoses; Nitriles; Pyridines; Randomized Controlled Trials as Topic; Treatment Outcome; Triazoles | 2015 |
In Vitro Activities of Eight Antifungal Drugs against a Global Collection of Genotyped Exserohilum Isolates.
Topics: Amphotericin B; Amplified Fragment Length Polymorphism Analysis; Antifungal Agents; Ascomycota; Caspofungin; Echinocandins; Fluconazole; Genotype; Itraconazole; Lipopeptides; Micafungin; Microbial Sensitivity Tests; Molecular Sequence Data; Nitriles; Pyridines; Triazoles; Voriconazole | 2015 |
In Vitro Susceptibility Profiles of Eight Antifungal Drugs against Clinical and Environmental Strains of Phaeoacremonium.
Topics: Amphotericin B; Anidulafungin; Antifungal Agents; Ascomycota; Caspofungin; Echinocandins; Fluconazole; Humans; Itraconazole; Lipopeptides; Microbial Sensitivity Tests; Mycoses; Nitriles; Pyridines; Triazoles; Voriconazole | 2015 |
Comparison of the EUCAST and CLSI Broth Microdilution Methods for Testing Isavuconazole, Posaconazole, and Amphotericin B against Molecularly Identified Mucorales Species.
Topics: Amphotericin B; Antifungal Agents; Humans; Microbial Sensitivity Tests; Mucorales; Mucormycosis; Nitriles; Pyridines; Species Specificity; Triazoles; Voriconazole | 2015 |
In Vitro Activity of Isavuconazole and Comparators against Clinical Isolates of the Mucorales Order.
Topics: Antifungal Agents; Fungi; Humans; Microbial Sensitivity Tests; Mucorales; Mucormycosis; Nitriles; Pyridines; Species Specificity; Triazoles | 2015 |
Activity of Isavuconazole and Other Azoles against Candida Clinical Isolates and Yeast Model Systems with Known Azole Resistance Mechanisms.
Topics: Alleles; Antifungal Agents; ATP Binding Cassette Transporter, Subfamily B, Member 1; Candida albicans; Candida glabrata; Candidiasis; Cytochrome P-450 Enzyme System; Drug Resistance, Fungal; Fluconazole; Fungal Proteins; Gene Expression Regulation, Fungal; Humans; Itraconazole; Membrane Transport Proteins; Microbial Sensitivity Tests; Mutation; Nitriles; Protein Isoforms; Pyridines; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins; Triazoles; Voriconazole | 2016 |
Pharmacodynamics of Isavuconazole in a Dynamic In Vitro Model of Invasive Pulmonary Aspergillosis.
Topics: Antifungal Agents; Area Under Curve; Aspergillus fumigatus; Bioreactors; Diffusion Chambers, Culture; Drug Resistance, Fungal; Galactose; Humans; Mannans; Microbial Sensitivity Tests; Models, Biological; Models, Statistical; Nitriles; Pulmonary Alveoli; Pyridines; Triazoles | 2016 |
Isavuconazole: a role for the newest broad-spectrum triazole.
Topics: Antifungal Agents; Female; Humans; Male; Mycoses; Nitriles; Pyridines; Triazoles; Voriconazole | 2016 |
Ceftazidime pentahydrate/avibactam sodium, Isavuconazonium sulfate, and Daclatasvir dihydrochloride.
Topics: Anti-Infective Agents; Azabicyclo Compounds; Carbamates; Ceftazidime; Drug Combinations; Humans; Imidazoles; Nitriles; Prodrugs; Pyridines; Pyrrolidines; Triazoles; Valine | 2016 |
Pharmacokinetics and Concentration-Dependent Efficacy of Isavuconazole for Treatment of Experimental Invasive Pulmonary Aspergillosis.
Topics: Animals; Antifungal Agents; Aspergillus fumigatus; Bronchoalveolar Lavage Fluid; Female; Galactose; Invasive Pulmonary Aspergillosis; Mannans; Nitriles; Pyridines; Rabbits; Triazoles | 2016 |
Isavuconazole: an azole active against mucormycosis.
Topics: Antifungal Agents; Azoles; Humans; Mucormycosis; Nitriles; Pyridines; Triazoles | 2016 |
[NEW ANTIFUNGAL DRUGS FOR PREVENTION AND TREATMENT OF VISCERAL MYCOSES].
Topics: Antifungal Agents; Caspofungin; Drug Therapy; Echinocandins; Humans; Lipopeptides; Micafungin; Mycoses; Nitriles; Pyridines; Treatment Outcome; Triazoles; Voriconazole | 2015 |
Isavuconazole Population Pharmacokinetic Analysis Using Nonparametric Estimation in Patients with Invasive Fungal Disease (Results from the VITAL Study).
Topics: Antifungal Agents; Aspergillosis; Aspergillus; Candida; Female; Humans; Linear Models; Male; Microbial Sensitivity Tests; Mucormycosis; Nitriles; Pyridines; Triazoles | 2016 |
New drugs 2016, part 2.
Topics: Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Benzimidazoles; Carbamates; Drug Approval; Drug Therapy; Humans; Imidazoles; Nitriles; Pyridines; Pyrrolidines; Quinolones; Thiophenes; Triazoles; United States; United States Food and Drug Administration; Valine | 2016 |
Isavuconazole Is Effective for the Treatment of Experimental Cryptococcal Meningitis.
Topics: Animals; Antifungal Agents; Brain; Cryptococcus neoformans; Disease Models, Animal; Meningitis, Cryptococcal; Mice; Microbial Sensitivity Tests; Nitriles; Pyridines; Triazoles | 2016 |
In Vitro Activity of Isavuconazole against Rasamsonia Species.
Topics: Antifungal Agents; Echinocandins; Eurotiales; Humans; Microbial Sensitivity Tests; Nitriles; Pyridines; Triazoles | 2016 |
Real-Life Use of Isavuconazole in Patients Intolerant to Other Azoles.
Topics: Antifungal Agents; Azoles; Drug Tolerance; Humans; Nitriles; Pyridines; Triazoles | 2016 |
Monotherapy or combination therapy of isavuconazole and micafungin for treating murine mucormycosis.
Topics: Animals; Antifungal Agents; Drug Therapy, Combination; Echinocandins; Lipopeptides; Lung; Male; Micafungin; Mice; Microbial Sensitivity Tests; Mucor; Mucormycosis; Nitriles; Pyridines; Rhizopus; Triazoles | 2017 |
Evaluation of MIC Strip Isavuconazole Test for Susceptibility Testing of Wild-Type and Non-Wild-Type Aspergillus fumigatus Isolates.
Topics: Antifungal Agents; Aspergillus fumigatus; Cytochrome P-450 Enzyme System; Fungal Proteins; Microbial Sensitivity Tests; Mutation; Nitriles; Pyridines; Triazoles | 2017 |
Physical compatibility of isavuconazonium sulfate with select i.v. drugs during simulated Y-site administration.
Topics: Antifungal Agents; Chemistry, Pharmaceutical; Drug Incompatibility; Drug Stability; Emulsions; Glucose; Humans; Infusions, Intravenous; Injections, Intravenous; Invasive Fungal Infections; Nephelometry and Turbidimetry; Nitriles; Pyridines; Sodium Chloride; Solubility; Time Factors; Triazoles | 2017 |
An ultra performance liquid chromatography-tandem mass spectrometry method for the therapeutic drug monitoring of isavuconazole and seven other antifungal compounds in plasma samples.
Topics: Antifungal Agents; Chromatography, High Pressure Liquid; Drug Monitoring; Humans; Linear Models; Nitriles; Pyridines; Reproducibility of Results; Sensitivity and Specificity; Tandem Mass Spectrometry; Triazoles | 2017 |
The cost of treating mucormycosis with isavuconazole compared with standard therapy in the UK.
Topics: Amphotericin B; Antifungal Agents; Case-Control Studies; Drug Costs; Hospitalization; Humans; Invasive Fungal Infections; Models, Economic; Mucormycosis; Nitriles; Pyridines; Triazoles; United Kingdom | 2017 |
In vitro combination therapy with isavuconazole against Candida spp.
Topics: Amphotericin B; Antifungal Agents; Candida; Candidiasis, Invasive; Drug Synergism; Echinocandins; In Vitro Techniques; Lipopeptides; Micafungin; Microbial Sensitivity Tests; Nitriles; Pyridines; Time Factors; Triazoles | 2017 |
Prophylaxis with Isavuconazole or Posaconazole Protects Immunosuppressed Mice from Pulmonary Mucormycosis.
Topics: Animals; Antibiotic Prophylaxis; Antifungal Agents; Disease Models, Animal; Immunosuppression Therapy; Lung Diseases, Fungal; Mice; Mucormycosis; Nitriles; Pyridines; Rhizopus; Triazoles; Voriconazole | 2017 |
Isavuconazole: is there a need for a new antifungal?
Topics: Antifungal Agents; Drug Discovery; Humans; Mycoses; Nitriles; Pyridines; Triazoles | 2017 |
New pharmacological opportunities for the treatment of invasive mould diseases.
Topics: Amphotericin B; Anidulafungin; Antibiotic Prophylaxis; Antifungal Agents; Aspergillosis; Drug Therapy, Combination; Echinocandins; Humans; Invasive Fungal Infections; Mucormycosis; Nitriles; Pyridines; Triazoles; Voriconazole | 2017 |
Design, synthesis, and in vitro evaluation of novel antifungal triazoles.
Topics: Antifungal Agents; Crystallography, X-Ray; Drug Design; Fungi; Microbial Sensitivity Tests; Molecular Conformation; Nitriles; Pyridines; Structure-Activity Relationship; Thiazoles; Triazoles | 2017 |
Use of isavuconazole in a patient with voriconazole-induced QTc prolongation.
Topics: Antifungal Agents; Cystic Fibrosis; Female; Humans; Long QT Syndrome; Lung Transplantation; Nitriles; Pyridines; Triazoles; Voriconazole; Young Adult | 2017 |
In vitro activity of the novel antifungal compound F901318 against difficult-to-treat Aspergillus isolates.
Topics: Acetamides; Antifungal Agents; Aspergillus; Aspergillus fumigatus; Cytochrome P-450 Enzyme System; Drug Resistance, Fungal; Fungal Proteins; Genotype; Humans; Invasive Pulmonary Aspergillosis; Itraconazole; Microbial Sensitivity Tests; Nitriles; Piperazines; Point Mutation; Pyridines; Pyrimidines; Pyrroles; Triazoles; Voriconazole | 2017 |
Effects of Isavuconazole on the Plasma Concentrations of Tacrolimus among Solid-Organ Transplant Patients.
Topics: Adult; Aged; Antifungal Agents; Cytochrome P-450 CYP3A; Cytochrome P-450 CYP3A Inhibitors; Drug Interactions; Drug Monitoring; Female; Heart Transplantation; Humans; Immunosuppressive Agents; Kidney Transplantation; Liver Transplantation; Lung Transplantation; Male; Middle Aged; Nitriles; Pyridines; Retrospective Studies; Tacrolimus; Transplant Recipients; Triazoles; Young Adult | 2017 |
Combination Therapy with Isavuconazole and Micafungin for Treatment of Experimental Invasive Pulmonary Aspergillosis.
Topics: Animals; Antifungal Agents; Combined Modality Therapy; Echinocandins; Female; Galactose; Glucans; Invasive Pulmonary Aspergillosis; Lipopeptides; Lung; Mannans; Micafungin; Nitriles; Pyridines; Rabbits; Triazoles | 2017 |
Reliable and Easy-To-Use Liquid Chromatography-Tandem Mass Spectrometry Method for Simultaneous Analysis of Fluconazole, Isavuconazole, Itraconazole, Hydroxy-Itraconazole, Posaconazole, and Voriconazole in Human Plasma and Serum.
Topics: Acetonitriles; Adult; Antifungal Agents; Calibration; Chromatography, Liquid; Drug Monitoring; Female; Fluconazole; Humans; Indicators and Reagents; Isotope Labeling; Itraconazole; Nitriles; Plasma; Pyridines; Reproducibility of Results; Tandem Mass Spectrometry; Triazoles; Voriconazole | 2017 |
A simple high performance liquid chromatography-mass spectrometry method for Therapeutic Drug Monitoring of isavuconazole and four other antifungal drugs in human plasma samples.
Topics: Antifungal Agents; Chromatography, High Pressure Liquid; Drug Monitoring; Humans; Nitriles; Pyridines; Tandem Mass Spectrometry; Triazoles | 2017 |
Topics: Anidulafungin; Antifungal Agents; Aspergillus flavus; Aspergillus fumigatus; Aspergillus nidulans; Aspergillus niger; Drug Combinations; Drug Resistance, Fungal; Humans; Micafungin; Microbial Sensitivity Tests; Nitriles; Pyridines; Triazoles | 2018 |
Isavuconazole susceptibility of clinical Aspergillus fumigatus isolates and feasibility of isavuconazole dose escalation to treat isolates with elevated MICs.
Topics: Antifungal Agents; Aspergillosis; Aspergillus fumigatus; Cytochrome P-450 Enzyme System; Drug Resistance, Fungal; Fungal Proteins; Humans; Itraconazole; Microbial Sensitivity Tests; Nitriles; Pyridines; Triazoles; Voriconazole | 2018 |
Furukawa Agar - A novel bacteriological agar designed to inhibit fungal contamination when sampling organic compost.
Topics: Agar; Antifungal Agents; Bacteria; Bacteriological Techniques; Cell Culture Techniques; Composting; Culture Media; Fungi; Nitriles; Pyridines; Specimen Handling; Triazoles | 2018 |
Real-world challenges and unmet needs in the diagnosis and treatment of suspected invasive pulmonary aspergillosis in patients with haematological diseases: An illustrative case study.
Topics: Amphotericin B; Anemia, Aplastic; Antifungal Agents; Aspergillus; Hematologic Diseases; Humans; Invasive Pulmonary Aspergillosis; Male; Neutropenia; Nitriles; Pyridines; Transaminases; Treatment Outcome; Triazoles; Voriconazole; Young Adult | 2018 |
Isavuconazole shortens the QTc interval.
Topics: Adult; Antifungal Agents; Electrocardiography; Female; Heart Conduction System; Humans; Invasive Fungal Infections; Male; Nitriles; Pyridines; Triazoles | 2018 |
In vitro activity of isavuconazole against fluconazole-resistant isolates of Histoplasma capsulatum.
Topics: Antifungal Agents; Drug Resistance, Fungal; Fluconazole; Histoplasma; Histoplasmosis; Humans; Microbial Sensitivity Tests; Nitriles; Pyridines; Recurrence; Triazoles | 2018 |
Hepatic veno-occlusive disease during isavuconazole administration.
Topics: Antifungal Agents; Hematopoietic Stem Cell Transplantation; Hepatic Veno-Occlusive Disease; Humans; Immunocompromised Host; Invasive Fungal Infections; Leukemia, Myeloid, Acute; Male; Nitriles; Pyridines; Triazoles; Young Adult | 2018 |
CYP51 is an essential drug target for the treatment of primary amoebic meningoencephalitis (PAM).
Topics: 14-alpha Demethylase Inhibitors; Amebicides; Animals; Antifungal Agents; Cell Proliferation; Central Nervous System Protozoal Infections; Disease Models, Animal; Drug Repositioning; Humans; Microscopy, Electron, Transmission; Naegleria fowleri; Nitriles; Pyridines; Sterol 14-Demethylase; Sterols; Triazoles; Trophozoites | 2017 |
Candida infanticola and Candida spencermartinsiae yeasts: Possible emerging species in cancer patients.
Topics: Adolescent; Antifungal Agents; Candida; Candidiasis; Caspofungin; Child, Preschool; Echinocandins; Fluconazole; Humans; Kluyveromyces; Lipopeptides; Male; Microbial Sensitivity Tests; Middle Aged; Neoplasms; Nitriles; Opportunistic Infections; Pichia; Pyridines; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Triazoles; Voriconazole | 2018 |
Comparative evaluation of different gradient diffusion tests for detection of azole resistance in Aspergillus fumigatus.
Topics: Antifungal Agents; Aspergillosis; Aspergillus fumigatus; Azoles; Disk Diffusion Antimicrobial Tests; Drug Resistance, Fungal; Itraconazole; Microbial Sensitivity Tests; Nitriles; Pyridines; Reproducibility of Results; Triazoles; Voriconazole | 2018 |
Improvement in Exophiala dermatitidis airway persistence and respiratory decline in response to interferon-gamma therapy in a patient with cystic fibrosis.
Topics: Amphotericin B; Antifungal Agents; Cystic Fibrosis; Disease Progression; Exophiala; Humans; Interferon-gamma; Interleukin-17; Lung Diseases, Fungal; Male; Monitoring, Immunologic; Nitriles; Pyridines; Recombinant Proteins; Respiratory Function Tests; Sputum; Treatment Outcome; Triazoles; Young Adult | 2018 |
Isavuconazole pharmacokinetics in a patient with cystic fibrosis following bilateral orthotopic lung transplantation.
Topics: Adult; Antifungal Agents; Cystic Fibrosis; Drug Monitoring; Female; Humans; Immunosuppressive Agents; Lung Transplantation; Nitriles; Pyridines; Triazoles; Young Adult | 2018 |
Diagnosis and management of Aspergillus diseases: executive summary of the 2017 ESCMID-ECMM-ERS guideline.
Topics: Antibodies, Fungal; Antifungal Agents; Aspergillosis; Aspergillus; Biopsy; Bronchoalveolar Lavage; Disease Management; Early Diagnosis; Flucytosine; Galactose; Humans; Immunocompromised Host; Immunologic Tests; Invasive Pulmonary Aspergillosis; Itraconazole; Leukemia, Myeloid, Acute; Magnetic Resonance Imaging; Mannans; Microbial Sensitivity Tests; Myelodysplastic Syndromes; Nitriles; Pyridines; Tomography, X-Ray Computed; Triazoles; Voriconazole | 2018 |
Isavuconazole therapy in an FLT3 mutated acute myeloid leukemia patient receiving midostaurin: A case report.
Topics: Adult; Antineoplastic Agents; Cytochrome P-450 CYP3A Inhibitors; fms-Like Tyrosine Kinase 3; Humans; Leukemia, Myeloid, Acute; Male; Mutation; Nitriles; Protein Kinase Inhibitors; Pyridines; Staurosporine; Triazoles | 2019 |
Anti-candidal activity of selected analgesic drugs used alone and in combination with fluconazole, itraconazole, voriconazole, posaconazole and isavuconazole.
Topics: Acetaminophen; Analgesics; Antifungal Agents; Aspirin; Candida; Candida albicans; Candida glabrata; Candidiasis; Dipyrone; Drug Resistance, Fungal; Fluconazole; Humans; Ibuprofen; Itraconazole; Meloxicam; Microbial Sensitivity Tests; Nitriles; Pyridines; Triazoles; Voriconazole | 2018 |
Breakthrough Invasive Fungal Infections on Isavuconazole Prophylaxis and Treatment: What Is Happening in the Real-World Setting?
Topics: Adult; Aged; Antifungal Agents; Female; Humans; Invasive Fungal Infections; Male; Middle Aged; Nitriles; Pyridines; Triazoles | 2018 |
High isavuconazole plasma levels in a patient with possible invasive pulmonary aspergillosis and cirrhosis.
Topics: Antifungal Agents; Humans; Invasive Pulmonary Aspergillosis; Liver Cirrhosis; Male; Middle Aged; Nitriles; Pyridines; Triazoles | 2018 |
Direct in vitro comparison of the prodrug isavuconazonium sulfate with the isavuconazole active compound against Aspergillus spp. and 2 rare moulds.
Topics: Antifungal Agents; Aspergillosis; Aspergillus; Humans; Mycoses; Nitriles; Prodrugs; Pyridines; Scedosporium; Triazoles | 2018 |
Isavuconazole Concentration in Real-World Practice: Consistency with Results from Clinical Trials.
Topics: Antifungal Agents; Clinical Trials as Topic; Humans; Itraconazole; Microbial Sensitivity Tests; Nitriles; Pyridines; Triazoles; Voriconazole | 2018 |
Pharmacokinetic/Pharmacodynamic Analysis of Isavuconazole Against Aspergillus spp. and Candida spp. in Healthy Subjects and Patients With Hepatic or Renal Impairment by Monte Carlo Simulation.
Topics: Antifungal Agents; Area Under Curve; Aspergillus; Candida; Dose-Response Relationship, Drug; Healthy Volunteers; Humans; Liver Diseases; Male; Microbial Sensitivity Tests; Monte Carlo Method; Nitriles; Pyridines; Renal Insufficiency; Species Specificity; Triazoles | 2018 |
Breakthrough Fungal Infections in Patients With Leukemia Receiving Isavuconazole.
Topics: Adult; Aged; Aged, 80 and over; Antifungal Agents; Candidemia; Electronic Health Records; Female; Humans; Invasive Fungal Infections; Leukemia; Male; Middle Aged; Nitriles; Pyridines; Retrospective Studies; Triazoles; Young Adult | 2018 |
Liquid chromatography-tandem mass spectrometry for the quantification of moxifloxacin, ciprofloxacin, daptomycin, caspofungin, and isavuconazole in human plasma.
Topics: Anti-Bacterial Agents; Antifungal Agents; Caspofungin; Chromatography, High Pressure Liquid; Ciprofloxacin; Daptomycin; Echinocandins; Fluoroquinolones; Humans; Limit of Detection; Lipopeptides; Moxifloxacin; Nitriles; Plasma; Pyridines; Reproducibility of Results; Spectrometry, Mass, Electrospray Ionization; Tandem Mass Spectrometry; Triazoles | 2018 |
Economic impact of treating invasive mold disease with isavuconazole compared with liposomal amphotericin B in the UK.
Topics: Amphotericin B; Antifungal Agents; Aspergillosis; Costs and Cost Analysis; Drug Costs; Health Care Costs; Humans; Models, Economic; Mucormycosis; Nitriles; Pyridines; Treatment Outcome; Triazoles; United Kingdom | 2018 |
Galleria mellonella as a model system to study virulence potential of mucormycetes and evaluation of antifungal treatment.
Topics: Amphotericin B; Animals; Antifungal Agents; Disease Models, Animal; Drug Resistance, Fungal; Larva; Lepidoptera; Microbial Sensitivity Tests; Mucor; Mucorales; Mucormycosis; Nitriles; Pyridines; Rhizopus; Triazoles; Virulence | 2019 |
Successful treatment of invasive mucormycosis with isavuconazole in pediatric patients.
Topics: Adolescent; Antifungal Agents; Antineoplastic Agents; Child, Preschool; Female; Hodgkin Disease; Humans; Immunocompromised Host; Male; Mucormycosis; Nitriles; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Pyridines; Treatment Outcome; Triazoles | 2018 |
Widespread Lichtheimia Infection in a Patient with Extensive Burns: Opportunities for Novel Antifungal Agents.
Topics: Amphotericin B; Antifungal Agents; Burns; Debridement; Dermatomycoses; Humans; Male; Middle Aged; Mucorales; Mucormycosis; Nitriles; Pyridines; Treatment Outcome; Triazoles | 2019 |
A sensitive and validated HPLC-UV method for the quantitative determination of the new antifungal drug isavuconazole in human plasma.
Topics: Antifungal Agents; Chromatography, High Pressure Liquid; Drug Stability; Humans; Limit of Detection; Linear Models; Nitriles; Pyridines; Reproducibility of Results; Spectrophotometry, Ultraviolet; Triazoles | 2018 |
Validation of an Isavuconazole High-Performance Liquid Chromatography Assay in Plasma for Routine Therapeutic Drug Monitoring Applications.
Topics: Antifungal Agents; Chromatography, High Pressure Liquid; Drug Monitoring; Humans; Nitriles; Pyridines; Triazoles | 2018 |
Isavuconazole is highly active in vitro against Candida species isolates but shows trailing effect.
Topics: Antifungal Agents; Candida; Candida albicans; Candida glabrata; Candidemia; Drug Resistance, Fungal; Humans; Microbial Sensitivity Tests; Nitriles; Pyridines; Triazoles | 2018 |
Isavuconazole for the treatment of invasive fungal disease in patients receiving ibrutinib.
Topics: Adenine; Antifungal Agents; Humans; Invasive Fungal Infections; Nitriles; Piperidines; Pyrazoles; Pyridines; Pyrimidines; Treatment Outcome; Triazoles | 2019 |
Quantification of Serum Voriconazole, Isavuconazole, and Posaconazole by Liquid Chromatography Tandem Mass Spectrometry (LC-MS/MS).
Topics: Antifungal Agents; Chromatography, Liquid; Humans; Nitriles; Pyridines; Tandem Mass Spectrometry; Triazoles; Voriconazole | 2018 |
Drug-Drug Interaction Between Isavuconazole and Tacrolimus: Is Empiric Dose Adjustment Necessary?
Topics: Allografts; Antifungal Agents; Drug Interactions; Drug Monitoring; Drug Tapering; Female; Humans; Immunosuppressive Agents; Middle Aged; Nitriles; Pyridines; Tacrolimus; Triazoles | 2020 |
Evaluation of isavuconazole MIC strips for susceptibility testing of Aspergillus and Scedosporium species.
Topics: Antifungal Agents; Aspergillus; Humans; Microbial Sensitivity Tests; Mycoses; Nitriles; Pyridines; Scedosporium; Triazoles | 2019 |
Tolerability of isavuconazole after posaconazole toxicity in leukaemia patients.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Chemical and Drug Induced Liver Injury; Drug-Related Side Effects and Adverse Reactions; Female; Humans; Leukemia; Liver Function Tests; Male; Middle Aged; Mycoses; Nitriles; Pyridines; Retrospective Studies; Triazoles; Young Adult | 2019 |
Has the Optimal Therapy for Invasive Candidiasis Now Been Defined?
Topics: Candida; Candidemia; Candidiasis, Invasive; Caspofungin; Humans; Nitriles; Pyridines; Triazoles | 2019 |
Effect of isavuconazole on tacrolimus and sirolimus serum concentrations in allogeneic hematopoietic stem cell transplant patients: A drug-drug interaction study.
Topics: Adult; Aged; Antifungal Agents; Cytochrome P-450 CYP3A; Cytochrome P-450 CYP3A Inhibitors; Drug Interactions; Drug Therapy, Combination; Female; Graft vs Host Disease; Hematopoietic Stem Cell Transplantation; Humans; Immunosuppressive Agents; Male; Middle Aged; Nitriles; Pyridines; Retrospective Studies; Sirolimus; Tacrolimus; Transplantation, Homologous; Triazoles; Young Adult | 2019 |
Isavuconazole Kinetic Exploration for Clinical Practice.
Topics: Administration, Oral; Adult; Aged; Antifungal Agents; Cytochrome P-450 CYP3A; Female; Humans; Kinetics; Male; Middle Aged; Nitriles; Polymorphism, Genetic; Pyridines; Triazoles | 2018 |
Inhibitory effect of isavuconazole, ketoconazole, and voriconazole on the pharmacokinetics of methadone in vivo and in vitro.
Topics: Analgesics, Opioid; Animals; Antifungal Agents; Ketoconazole; Male; Methadone; Nitriles; Pyridines; Rats, Sprague-Dawley; Triazoles; Voriconazole | 2019 |
Preexposure to Isavuconazole Increases the Virulence of
Topics: Animals; Antifungal Agents; Aspergillus fumigatus; Drosophila melanogaster; Female; Mucorales; Nitriles; Pyridines; Rhizopus; Triazoles; Virulence | 2019 |
Isavuconazole: Case Report and Pharmacokinetic Considerations.
Topics: Administration, Oral; Antifungal Agents; Aspergillosis; Aspergillus flavus; Bronchoalveolar Lavage Fluid; Chemical and Drug Induced Liver Injury; Chromatography, High Pressure Liquid; Drug Monitoring; Female; Half-Life; Humans; Immunocompromised Host; Nitriles; Pyridines; Tandem Mass Spectrometry; Triazoles; Voriconazole; Young Adult | 2018 |
Successful outcome of disseminated mucormycosis in a 3-year-old child suffering from acute leukaemia: the role of isavuconazole? A case report.
Topics: Acute Disease; Amphotericin B; Antifungal Agents; Child, Preschool; Drug Therapy, Combination; Female; Humans; Leukemia, B-Cell; Mucormycosis; Nitriles; Pyridines; Treatment Outcome; Triazoles | 2018 |
Isavuconazole in the Treatment of Coccidioidal Meningitis.
Topics: Adult; Antifungal Agents; Coccidioidomycosis; Female; Humans; Male; Meningitis, Fungal; Middle Aged; Nitriles; Pyridines; Retrospective Studies; Treatment Outcome; Triazoles | 2019 |
Isavuconazole and voriconazole for the treatment of chronic pulmonary aspergillosis: A retrospective comparison of rates of adverse events.
Topics: Adult; Aged; Aged, 80 and over; Antifungal Agents; Chronic Disease; Drug-Related Side Effects and Adverse Reactions; Female; Humans; Male; Middle Aged; Nitriles; Pulmonary Aspergillosis; Pyridines; Retrospective Studies; Triazoles; United Kingdom; Voriconazole | 2019 |
The pharmacokinetic challenge of treating invasive aspergillosis complicating severe influenzae assisted by extracorporeal membrane oxygenation.
Topics: Antifungal Agents; Aspergillosis; Aspergillus fumigatus; Bronchopulmonary Sequestration; Extracorporeal Membrane Oxygenation; Humans; Influenza, Human; Invasive Fungal Infections; Male; Middle Aged; Nitriles; Pyridines; Triazoles; Voriconazole | 2018 |
Therapeutic drug concentrations of isavuconazole following the administration of isavuconazonium sulfate capsules via gastro-jejunum tube: A case report.
Topics: Aged; Antifungal Agents; Aspergillosis; Capsules; Drug Monitoring; Enteral Nutrition; Humans; Immunocompromised Host; Invasive Fungal Infections; Jejunum; Lung Transplantation; Male; Nitriles; Pyridines; Triazoles | 2019 |
Cost-effectiveness analysis of isavuconazole versus voriconazole for the treatment of patients with possible invasive aspergillosis in Sweden.
Topics: Adult; Amphotericin B; Antifungal Agents; Aspergillosis; Case-Control Studies; Cost-Benefit Analysis; Decision Trees; Female; Humans; Invasive Fungal Infections; Mucormycosis; Nitriles; Pyridines; Quality-Adjusted Life Years; Sweden; Triazoles; Voriconazole | 2019 |
Isavuconazole brain penetration in cerebral aspergillosis.
Topics: Antifungal Agents; Humans; Infectious Encephalitis; Neuroaspergillosis; Nitriles; Permeability; Pyridines; Tissue Distribution; Triazoles | 2019 |
Isavuconazole MIC distribution of 29 yeast species responsible for invasive infections (2015-2017).
Topics: Antifungal Agents; Fluconazole; Humans; Invasive Fungal Infections; Microbial Sensitivity Tests; Nitriles; Pyridines; Triazoles; Yeasts | 2019 |
Real-world use-Isavuconazole at a large academic medical center.
Topics: Academic Medical Centers; Adult; Aged; Aged, 80 and over; Antifungal Agents; Chemoprevention; Drug Substitution; Drug-Related Side Effects and Adverse Reactions; Female; Humans; Male; Middle Aged; Mycoses; Nitriles; Pyridines; Retrospective Studies; Survival Analysis; Treatment Outcome; Triazoles; United States | 2019 |
Lack of Toxicity With Long-term Isavuconazole Use in Patients With Hematologic Malignancy.
Topics: Adult; Aged; Aged, 80 and over; Antifungal Agents; Female; Hematologic Neoplasms; Humans; Liver; Male; Middle Aged; Nitriles; Pyridines; Retrospective Studies; Skin; Triazoles; Young Adult | 2019 |
Comparative evaluation of isavuconazonium sulfate, voriconazole, and posaconazole for the management of invasive fungal infections in an academic medical center.
Topics: Academic Medical Centers; Adult; Aged; Antifungal Agents; Female; Humans; Invasive Fungal Infections; Male; Middle Aged; Nitriles; Pyridines; Retrospective Studies; Triazoles; Voriconazole; Young Adult | 2019 |
Antifungal Drugs Influence Neutrophil Effector Functions.
Topics: Amphotericin B; Antifungal Agents; Interleukin-8; Neutrophils; Nitriles; Phagocytosis; Pyridines; Triazoles; Voriconazole | 2019 |
In vitro interactions between isavuconazole and tacrolimus, cyclosporin A or sirolimus against Mucorales.
Topics: Antifungal Agents; Cyclosporine; Immunosuppressive Agents; Microbial Sensitivity Tests; Mucorales; Mucormycosis; Nitriles; Pyridines; Sirolimus; Tacrolimus; Triazoles | 2019 |
Isavuconazole Prophylaxis in Patients With Hematologic Malignancies and Hematopoietic Cell Transplant Recipients.
Topics: Adult; Antifungal Agents; Hematologic Neoplasms; Hematopoietic Stem Cell Transplantation; Humans; Nitriles; Pyridines; Retrospective Studies; Transplant Recipients; Triazoles | 2020 |
No Dose Adjustment for Isavuconazole Based on Age or Sex.
Topics: Adult; Antifungal Agents; Confidence Intervals; Female; Humans; Male; Nitriles; Pyridines; Triazoles; Young Adult | 2019 |
Tissue Distribution and Penetration of Isavuconazole at the Site of Infection in Experimental Invasive Aspergillosis in Mice with Underlying Chronic Granulomatous Disease.
Topics: Administration, Oral; Animals; Antifungal Agents; Aspergillosis; Chromatography, Liquid; Disease Models, Animal; Granulomatous Disease, Chronic; Invasive Fungal Infections; Male; Mice; Nitriles; Prodrugs; Pyridines; Tandem Mass Spectrometry; Tissue Distribution; Triazoles | 2019 |
Isavuconazole to prevent invasive fungal infection in immunocompromised adults: Initial experience at an academic medical centre.
Topics: Academic Medical Centers; Adult; Antifungal Agents; Chemoprevention; Cost-Benefit Analysis; Female; Humans; Immunocompromised Host; Inpatients; Invasive Fungal Infections; Male; Middle Aged; Nitriles; Oregon; Pyridines; Retrospective Studies; Risk Factors; Triazoles | 2019 |
Disseminated mucormycosis.
Topics: Antifungal Agents; Female; Humans; Leukemia, Myeloid; Middle Aged; Mucormycosis; Nitriles; Opportunistic Infections; Pyridines; Respiratory Insufficiency; Shock, Septic; Tomography, X-Ray Computed; Triazoles | 2019 |
Isavuconazole Treatment of Cerebral and Pulmonary Aspergillosis in a Pediatric Patient With Acute Lymphoblastic Leukemia: Case Report and Review of Literature.
Topics: Antifungal Agents; Antineoplastic Combined Chemotherapy Protocols; Aspergillus; Child, Preschool; Female; Humans; Neuroaspergillosis; Nitriles; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Prognosis; Pulmonary Aspergillosis; Pyridines; Triazoles | 2020 |
Serial monitoring of isavuconazole blood levels during prolonged antifungal therapy.
Topics: Adult; Aged; Aged, 80 and over; Antifungal Agents; Drug Monitoring; Drug-Related Side Effects and Adverse Reactions; Female; Humans; Invasive Fungal Infections; Male; Middle Aged; Nitriles; Pyridines; Retrospective Studies; ROC Curve; Serum; Triazoles | 2019 |
Unexpected analytical interference in isavuconazole UV determination in a child in therapy with lumacaftor/ivacaftor for cystic fibrosis.
Topics: Aminophenols; Aminopyridines; Antifungal Agents; Antineoplastic Combined Chemotherapy Protocols; Benzodioxoles; Cystic Fibrosis; Female; Humans; Male; Nitriles; Pyridines; Quinolones; Triazoles | 2019 |
A Revised Species Concept for Opportunistic
Topics: Amphotericin B; Antifungal Agents; Humans; Itraconazole; Microbial Sensitivity Tests; Mucor; Mucormycosis; Natamycin; Nitriles; Pyridines; Rhizopus; Species Specificity; Terbinafine; Triazoles | 2019 |
Pharmacodynamics of Isavuconazole in a Rabbit Model of Cryptococcal Meningoencephalitis.
Topics: Animals; Antifungal Agents; Area Under Curve; Brain; Cryptococcus neoformans; Disease Models, Animal; Male; Meningitis, Cryptococcal; Meningoencephalitis; Microbial Sensitivity Tests; Models, Theoretical; Nitriles; Pyridines; Rabbits; Triazoles | 2019 |
The cost-effectiveness of isavuconazole compared to the standard of care in the treatment of patients with invasive fungal infection prior to differential pathogen diagnosis in the United Kingdom.
Topics: Antifungal Agents; Cost-Benefit Analysis; Decision Trees; Diagnosis, Differential; Health Expenditures; Health Resources; Health Services; Hospitalization; Humans; Invasive Fungal Infections; Models, Economic; Nitriles; Prescription Fees; Pyridines; Quality-Adjusted Life Years; State Medicine; Survival Analysis; Triazoles; Uncertainty; United Kingdom; Voriconazole | 2020 |
Isavuconazole and voriconazole inhibition of sterol 14α-demethylases (CYP51) from Aspergillus fumigatus and Homo sapiens.
Topics: 14-alpha Demethylase Inhibitors; Antifungal Agents; Aspergillus fumigatus; Cytochrome P450 Family 51; Humans; Inhibitory Concentration 50; Nitriles; Protein Binding; Pyridines; Recombinant Proteins; Sterols; Triazoles; Voriconazole | 2019 |
Evaluation of the Gradient Concentration Strip Method for Antifungal Susceptibility Testing of Isavuconazole and Comparators for
Topics: Amphotericin B; Antifungal Agents; Azoles; Humans; Itraconazole; Microbial Sensitivity Tests; Mucorales; Nitriles; Pyridines; Triazoles | 2019 |
Isavuconazole Diffusion in Infected Human Brain.
Topics: Adult; Aspergillosis; Aspergillus fumigatus; Brain; Cerebrospinal Fluid; Female; Granulomatous Disease, Chronic; Humans; Magnetic Resonance Imaging; Nitriles; Pyridines; Triazoles; Young Adult | 2019 |
Influence of Sustained Low-Efficiency Dialysis Treatment on Isavuconazole Plasma Levels in Critically Ill Patients.
Topics: Adult; Antifungal Agents; Aspergillosis; Aspergillus; Critical Illness; Female; Humans; Male; Microbial Sensitivity Tests; Middle Aged; Nitriles; Pyridines; Triazoles | 2019 |
Invasive Fungal Disease, Isavuconazole Treatment Failure, and Death in Acute Myeloid Leukemia Patients.
Topics: Antifungal Agents; Aspergillus fumigatus; Diagnosis, Differential; Fatal Outcome; Humans; Immunocompromised Host; Leukemia, Myeloid, Acute; Male; Middle Aged; Nitriles; Pulmonary Aspergillosis; Pyridines; Treatment Failure; Triazoles | 2019 |
Treatment Failure of Isavuconazole in a Patient with Cryptococcosis.
Topics: Antifungal Agents; Cryptococcosis; Humans; Invasive Fungal Infections; Lung Diseases, Fungal; Male; Middle Aged; Nitriles; Pyridines; Treatment Failure; Triazoles | 2019 |
Successful Treatment of Severe Aspergillosis with Isavuconazole Therapy after Allogeneic Stem Cell Transplantation.
Topics: Adult; Antifungal Agents; Aspergillosis; Aspergillus fumigatus; DNA, Fungal; Graft vs Host Disease; Hematopoietic Stem Cell Transplantation; Humans; Male; Nitriles; Pyridines; Thorax; Transplantation, Homologous; Triazoles | 2019 |
Real-life use of isavuconazole outside the hematological wards.
Topics: Adult; Aged; Antifungal Agents; Female; Humans; Immunocompromised Host; Invasive Fungal Infections; Italy; Male; Middle Aged; Nitriles; Pyridines; Triazoles | 2019 |
Isavuconazole-induced Acute Liver Failure in a Pediatric Patient With Invasive Aspergillosis.
Topics: Adolescent; Antifungal Agents; Bone Marrow Transplantation; Humans; Invasive Pulmonary Aspergillosis; Liver Failure, Acute; Male; Nitriles; Pyridines; Triazoles | 2019 |
Interlaboratory Analysis of Isavuconazole Plasma Concentration Assays Among European Laboratories.
Topics: Biological Assay; Chromatography, Liquid; Drug Monitoring; Europe; Humans; Laboratories; Nitriles; Plasma; Pyridines; Reproducibility of Results; Tandem Mass Spectrometry; Triazoles | 2019 |
Use of triazoles for the treatment of invasive aspergillosis: A three-year cohort analysis.
Topics: Adult; Aged; Aged, 80 and over; Antifungal Agents; Aspergillosis; Cohort Studies; Female; Humans; Invasive Fungal Infections; Male; Middle Aged; Nitriles; Pyridines; Treatment Outcome; Triazoles; Voriconazole | 2020 |
Isavuconazole for the treatment of patients with invasive fungal diseases involving the central nervous system.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antifungal Agents; Central Nervous System Fungal Infections; Child; Child, Preschool; Clinical Trials, Phase III as Topic; Drug Resistance, Fungal; Female; Fungi; Humans; Invasive Fungal Infections; Male; Middle Aged; Nitriles; Pyridines; Retrospective Studies; Survival Analysis; Triazoles; Young Adult | 2020 |
Successful treatment with isavuconazole of subcutaneous phaeohyphomycosis in a kidney transplant recipient.
Topics: Aged; Alternaria; Antifungal Agents; Humans; Immunocompromised Host; Kidney Failure, Chronic; Kidney Transplantation; Male; Nitriles; Phaeohyphomycosis; Pyridines; Subcutaneous Tissue; Treatment Outcome; Triazoles | 2019 |
Identification and structural characterization of four novel degradation products and a process impurity of isavuconazonium sulfate for injection formulation bulk by LC-ESI-QTOF-MS/MS.
Topics: Chromatography, Liquid; Drug Contamination; Drug Stability; Nitriles; Pyridines; Spectrometry, Mass, Electrospray Ionization; Tandem Mass Spectrometry; Triazoles | 2020 |
Topics: Antifungal Agents; Fusariosis; Fusarium; Microbial Sensitivity Tests; Nitriles; Pyridines; Triazoles | 2020 |
Comparison of the MICs Obtained by Gradient Concentration Strip and EUCAST Methods for Four Azole Drugs and Amphotericin B against Azole-Susceptible and -Resistant
Topics: Amphotericin B; Antifungal Agents; Aspergillus; Aspergillus fumigatus; Azoles; Drug Resistance, Fungal; Fungal Proteins; Itraconazole; Microbial Sensitivity Tests; Nitriles; Pyridines; Triazoles; Voriconazole | 2020 |
The antifungal isavuconazole inhibits the entry of lassa virus by targeting the stable signal peptide-GP2 subunit interface of lassa virus glycoprotein.
Topics: A549 Cells; Antifungal Agents; Antiviral Agents; Cell Line; Drug Repositioning; Glycoproteins; HEK293 Cells; Humans; Lassa Fever; Lassa virus; Nitriles; Protein Sorting Signals; Pyridines; Triazoles; Viral Envelope Proteins; Viral Proteins; Virus Internalization | 2020 |
Successful Treatment of Invasive Fungal Infection Due to Highly Resistant Aspergillus calidoustus in an Allogeneic Hematopoietic Cell Transplant Recipient.
Topics: Antifungal Agents; Aspergillosis; Aspergillus; Azoles; Drug Resistance, Fungal; Female; Hematopoietic Stem Cell Transplantation; Humans; Invasive Fungal Infections; Microbial Sensitivity Tests; Middle Aged; Nitriles; Primary Myelofibrosis; Pyridines; Triazoles | 2020 |
Primary cutaneous mucormycosis of the abdomen at the site of repeated insulin injections.
Topics: Abdomen; Aged; Anti-Bacterial Agents; Antifungal Agents; Dermatomycoses; Diabetes Mellitus, Type 2; Female; Humans; Immunocompromised Host; Injection Site Reaction; Injections, Subcutaneous; Insulin; Lung Neoplasms; Mucormycosis; Necrosis; Nitriles; Pyridines; Triazoles; Vancomycin | 2020 |
In vitro activity of isavuconazole versus opportunistic filamentous fungal pathogens from the SENTRY Antifungal Surveillance Program, 2017-2018.
Topics: Antifungal Agents; Aspergillosis; Aspergillus; Aspergillus fumigatus; Drug Resistance, Fungal; Fungi; Humans; Microbial Sensitivity Tests; Nitriles; Public Health Surveillance; Pyridines; Triazoles; Voriconazole | 2020 |
A Single-Center, Open-Label Trial of Isavuconazole Prophylaxis against Invasive Fungal Infection in Patients Undergoing Allogeneic Hematopoietic Cell Transplantation.
Topics: Adult; Aged; Antifungal Agents; Hematopoietic Stem Cell Transplantation; Humans; Invasive Fungal Infections; Middle Aged; Nitriles; Pyridines; Retrospective Studies; Triazoles | 2020 |
Ibrutinib related cerebral aspergillosis successfully treated with isavuconazole: a case report.
Topics: Adenine; Antifungal Agents; Aspergillosis; Humans; Nitriles; Piperidines; Pyridines; Triazoles | 2020 |
The Antifungal Drug Isavuconazole Is both Amebicidal and Cysticidal against Acanthamoeba castellanii.
Topics: 14-alpha Demethylase Inhibitors; Acanthamoeba castellanii; Amebiasis; Amebicides; Animals; Antifungal Agents; Drug Repositioning; Humans; Microbial Sensitivity Tests; Nitriles; Pyridines; Triazoles; Trophozoites | 2020 |
In vitro activity of isavuconazole against three species of Acanthamoeba.
Topics: Acanthamoeba; Acanthamoeba castellanii; Acanthamoeba Keratitis; Animals; Dose-Response Relationship, Drug; Humans; Nitriles; Parasite Encystment; Parasitic Sensitivity Tests; Pyridines; Triazoles; Trophozoites | 2020 |
Safety of Isavuconazonium Sulfate in Pediatrics Patients With Hematologic Malignancies and Hematopoietic Cell Transplantation With Invasive Fungal Infections: A Real World Experience.
Topics: Adolescent; Child; Child, Preschool; Female; Hematologic Neoplasms; Hematopoietic Stem Cell Transplantation; Humans; Invasive Fungal Infections; Male; Nitriles; Pyridines; Retrospective Studies; Triazoles | 2020 |
Isavuconazole As Successful Salvage Therapy for Mucormycosis in Pediatric Patients.
Topics: Adolescent; Antifungal Agents; Child; Child, Preschool; Female; Humans; Male; Mucormycosis; Nitriles; Pyridines; Salvage Therapy; Tertiary Healthcare; Tomography, X-Ray Computed; Triazoles; Young Adult | 2020 |
18F-FDG Positron Emission Tomography (PET) Scan as a Useful Tool to Assess Response to Antimycotic Therapy in Disseminated Invasive Mycosis in Acute Myeloid Leukemia.
Topics: Aged; Anidulafungin; Antifungal Agents; Drug Combinations; Humans; Immunocompromised Host; Invasive Fungal Infections; Kidney; Leukemia, Myeloid, Acute; Liver; Male; Mycoses; Nitriles; Positron-Emission Tomography; Pyridines; Spleen; Treatment Outcome; Triazoles | 2020 |
COVID-19 associated pulmonary aspergillosis.
Topics: Aged; Antifungal Agents; Bronchoalveolar Lavage Fluid; Coronavirus Infections; COVID-19; Female; Galactose; Germany; Hemorrhage; Hospitals, Teaching; Humans; Intensive Care Units; Lung Diseases; Male; Mannans; Metapneumovirus; Middle Aged; Nitriles; Pandemics; Paramyxoviridae Infections; Pneumonia, Viral; Pulmonary Aspergillosis; Pyridines; Respiratory Distress Syndrome; Retrospective Studies; Thorax; Tomography, X-Ray Computed; Triazoles; Voriconazole | 2020 |
Intravenous isavuconazole can be administered 5 days-a-week. A possibility suggested by a real-life observation.
Topics: Administration, Intravenous; Antifungal Agents; Aspergillosis; Child; Drug Monitoring; Humans; Male; Nitriles; Precursor T-Cell Lymphoblastic Leukemia-Lymphoma; Pyridines; Triazoles | 2020 |
Successful treatment of Aspergillus fumigatus sternal osteomyelitis with isavuconazole in a heart transplant recipient.
Topics: Aged; Antifungal Agents; Aspergillus fumigatus; Heart Transplantation; Humans; Male; Nitriles; Osteomyelitis; Pyridines; Triazoles; Voriconazole | 2020 |
Lessons from isavuconazole therapeutic drug monitoring at a United Kingdom Reference Center.
Topics: Adolescent; Adult; Age Factors; Aged; Aged, 80 and over; Antifungal Agents; Child; Child, Preschool; Drug Monitoring; Drug-Related Side Effects and Adverse Reactions; Female; Humans; Male; Middle Aged; Mycoses; Nitriles; Pyridines; Serum; Sex Factors; Triazoles; United Kingdom; Young Adult | 2020 |
Should
Topics: Anti-Infective Agents; Continuous Renal Replacement Therapy; Nitriles; Pyridines; Renal Replacement Therapy; Triazoles | 2020 |
Reply to Baud and Houzé, "Should
Topics: Anti-Infective Agents; Continuous Renal Replacement Therapy; Nitriles; Pyridines; Renal Replacement Therapy; Triazoles | 2020 |
Isavuconazole Is as Effective as and Better Tolerated Than Voriconazole for Antifungal Prophylaxis in Lung Transplant Recipients.
Topics: Antifungal Agents; Humans; Lung; Nitriles; Pyridines; Retrospective Studies; Transplant Recipients; Triazoles; Voriconazole | 2021 |
In vitro interaction of isavuconazole and anidulafungin against azole-susceptible and azole-resistant Aspergillus fumigatus isolates.
Topics: Anidulafungin; Antifungal Agents; Aspergillus fumigatus; Azoles; Drug Resistance, Fungal; Fungal Proteins; Humans; Microbial Sensitivity Tests; Nitriles; Pyridines; Triazoles | 2020 |
Revision of EUCAST breakpoints: consequences for susceptibility of contemporary Danish mould isolates to isavuconazole and comparators.
Topics: Antifungal Agents; Aspergillus; Aspergillus fumigatus; Denmark; Drug Resistance, Fungal; Microbial Sensitivity Tests; Nitriles; Pyridines; Triazoles; Voriconazole | 2020 |
Topics: Antifungal Agents; Ascomycota; Fungi; Microbial Sensitivity Tests; Nitriles; Pyridines; Thiazoles; Triazoles; Voriconazole | 2020 |
In vitro activity of isavuconazole against clinically isolated yeasts from Chile.
Topics: Antifungal Agents; Chile; Humans; Microbial Sensitivity Tests; Mycoses; Nitriles; Pyridines; Triazoles; Yeasts | 2020 |
Achievement of clinical isavuconazole blood concentrations in transplant recipients with isavuconazonium sulphate capsules administered via enteral feeding tube.
Topics: Antifungal Agents; Capsules; Enteral Nutrition; Humans; Nitriles; Pyridines; Transplant Recipients; Triazoles | 2020 |
Isavuconazole for the prophylaxis and treatment of invasive fungal disease: A single-center experience.
Topics: Antifungal Agents; Humans; Invasive Fungal Infections; Nitriles; Pyridines; Retrospective Studies; Triazoles | 2021 |
The cost-effectiveness of isavuconazole compared to voriconazole, the standard of care in the treatment of patients with invasive mould diseases, prior to differential pathogen diagnosis in Spain.
Topics: Antifungal Agents; Aspergillosis; Clinical Laboratory Techniques; Cost-Benefit Analysis; Diagnosis, Differential; Fungi; Hospitalists; Humans; Mucormycosis; Nitriles; Pyridines; Spain; Standard of Care; Triazoles; Voriconazole | 2021 |
Principal-agent theory-based cost and reimbursement structures of isavuconazole treatment in German hospitals.
Topics: Cost-Benefit Analysis; Costs and Cost Analysis; Diagnosis-Related Groups; Economics, Hospital; Germany; Hospitals; Humans; Length of Stay; Nitriles; Pyridines; Triazoles | 2021 |
Isolated cerebral mucormycosis associated with intravenous drug use.
Topics: Amphotericin B; Central Nervous System Fungal Infections; Cocaine; Cocaine-Related Disorders; Drug Therapy, Combination; Drug Users; Humans; Magnetic Resonance Imaging; Male; Marijuana Abuse; Middle Aged; Mucormycosis; Nitriles; Pyridines; Substance Abuse, Intravenous; Triazoles | 2020 |
Characterization of Isavuconazole serum concentrations after enteral feeding tube administration in a hospitalized cohort: A case series.
Topics: Adult; Antifungal Agents; Drug Administration Routes; Enteral Nutrition; Female; Humans; Invasive Fungal Infections; Male; Middle Aged; Nitriles; Pyridines; Triazoles | 2021 |
In vitro synergy of isavuconazole in combination with colistin against Candida auris.
Topics: Agar; Antifungal Agents; Candida; Candidiasis; Colistin; Colony Count, Microbial; Drug Synergism; Humans; Microbial Sensitivity Tests; Nitriles; Pyridines; Triazoles | 2020 |
Antifungal efficacy of isavuconazole and liposomal amphotericin B in a rabbit model of Exserohilum rostratum meningoencephalitis: A preclinical paradigm for management of CNS phaeohyphomycosis.
Topics: Amphotericin B; Animals; Antifungal Agents; Ascomycota; Central Nervous System Diseases; Disease Management; Disease Models, Animal; Drug Therapy, Combination; Female; Humans; Microbial Sensitivity Tests; Nitriles; Phaeohyphomycosis; Pyridines; Rabbits; Triazoles | 2021 |
Isavuconazole as Salvage Therapy for Refractory Pediatric Coccidioidal Meningitis.
Topics: Amphotericin B; Antifungal Agents; Child; Coccidioides; Coccidioidomycosis; Deoxycholic Acid; Drug Combinations; Humans; Meningitis, Fungal; Nitriles; Pyridines; Salvage Therapy; Triazoles; Voriconazole | 2021 |
[Treatment of chromoblastomycosis and phaeohyphomycosis].
Topics: Antifungal Agents; Chromoblastomycosis; Humans; Nitriles; Phaeohyphomycosis; Pyridines; Triazoles | 2020 |
Identification and molecular characterization of Subramaniula asteroides causing human fungal keratitis: a case report.
Topics: Aged; Antifungal Agents; Corneal Ulcer; Diagnosis, Differential; Eye Infections, Fungal; Humans; Male; Nitriles; Ophthalmic Solutions; Pyridines; Sordariales; Triazoles | 2021 |
A 51-Year-Old Woman With a Mediastinal Mass.
Topics: Amphotericin B; Antifungal Agents; Bronchoscopy; Diagnosis, Differential; Female; Humans; Lung; Lung Diseases; Middle Aged; Mucormycosis; Nitriles; Pneumonectomy; Pyridines; Respiration, Artificial; Thoracic Surgery, Video-Assisted; Treatment Outcome; Triazoles | 2021 |
Isavuconazole nonwildtype Aspergillus fumigatus isolates from a global surveillance study display alterations in multiple genes involved in the ergosterol biosynthesis pathway not previously associated with resistance to other azoles.
Topics: Antifungal Agents; Aspergillus fumigatus; Azoles; Drug Resistance, Fungal; Ergosterol; Fungal Proteins; Humans; Itraconazole; Microbial Sensitivity Tests; Nitriles; Pyridines; Triazoles; Voriconazole; Whole Genome Sequencing | 2021 |
The antifungal drug isavuconazole inhibits the replication of human cytomegalovirus (HCMV) and acts synergistically with anti-HCMV drugs.
Topics: Antifungal Agents; Antiviral Agents; Cell Line; Cytomegalovirus; Cytomegalovirus Infections; Drug Repositioning; Drug Resistance, Viral; Drug Synergism; Drug Therapy, Combination; Humans; Nitriles; Pyridines; Sterol 14-Demethylase; Triazoles; Virus Replication | 2021 |
Identification and in vitro antifungal susceptibility of causative agents of onychomycosis due to Aspergillus species in Mashhad, Iran.
Topics: Antifungal Agents; Aspergillus; Calmodulin; Fungal Proteins; Humans; Iran; Microbial Sensitivity Tests; Nitriles; Onychomycosis; Pyridines; Sequence Analysis, DNA; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Triazoles; Tubulin; Voriconazole | 2021 |
Concomitant use of isavuconazole and CYP3A4/5 inducers: Where pharmacogenetics meets pharmacokinetics.
Topics: Alleles; Cytochrome P-450 CYP3A; Cytochrome P-450 CYP3A Inducers; Genotype; Humans; Nitriles; Pharmacogenetics; Pyridines; Rifampin; Triazoles | 2021 |
Enteral tube administration of isavuconazole in a pediatric patient.
Topics: Child; Humans; Intubation, Gastrointestinal; Nitriles; Pyridines; Triazoles | 2021 |
In vitro and in vivo interaction of caspofungin with isavuconazole against Candida auris planktonic cells and biofilms.
Topics: Animals; Antifungal Agents; Biofilms; Candida; Candida auris; Caspofungin; Mice; Microbial Sensitivity Tests; Nitriles; Plankton; Pyridines; Triazoles | 2021 |
Safety, Tolerability, and Population Pharmacokinetics of Intravenous and Oral Isavuconazonium Sulfate in Pediatric Patients.
Topics: Administration, Oral; Adolescent; Child; Child, Preschool; Humans; Infant; Invasive Fungal Infections; Nitriles; Pyridines; Triazoles | 2021 |
Efficacy and safety of isavuconazole compared with voriconazole as primary antifungal prophylaxis in allogeneic hematopoietic cell transplant recipients.
Topics: Animals; Antifungal Agents; Hematopoietic Stem Cell Transplantation; Humans; Nitriles; Pyridines; Retrospective Studies; Transplant Recipients; Triazoles; Voriconazole | 2021 |
Successful Isavuconazole Salvage Therapy for a Cryptococcus deuterogattii (AFLP6/VGII) Disseminated Infection in a European Immunocompetent Patient.
Topics: Antifungal Agents; Cryptococcosis; Cryptococcus gattii; Genotype; Humans; Nitriles; Pyridines; Salvage Therapy; Triazoles | 2021 |
Reimbursement of innovative pharmaceuticals in English and Spanish hospitals-The example of isavuconazole.
Topics: Antifungal Agents; England; Health Care Costs; Hospitals; Humans; Inpatients; Insurance, Health, Reimbursement; Nitriles; Pyridines; Spain; Triazoles | 2021 |
Antifungal drugs work together to treat germs causing fungal infections.
Topics: Anidulafungin; Antifungal Agents; Candida auris; Candidiasis, Invasive; Drug Resistance, Fungal; Drug Therapy, Combination; Humans; Nitriles; Pyridines; Triazoles; Voriconazole | 2021 |
Comparative effects of fluconazole, posaconazole, and isavuconazole upon tacrolimus and cyclosporine serum concentrations.
Topics: Antifungal Agents; Cyclosporine; Fluconazole; Hematopoietic Stem Cell Transplantation; Humans; Immunosuppressive Agents; Nitriles; Pyridines; Retrospective Studies; Tacrolimus; Triazoles | 2022 |
Combination treatment of liposomal amphotericin B and isavuconazole is synergistic in treating experimental mucormycosis.
Topics: Amphotericin B; Animals; Antifungal Agents; Mice; Mucor; Mucormycosis; Nitriles; Pyridines; Rhizopus; Triazoles | 2021 |
Clinical Considerations of Isavuconazole Administration in High-Risk Hematological Patients: A Single-Center 5-Year Experience.
Topics: Antifungal Agents; Hematopoietic Stem Cell Transplantation; Humans; Nitriles; Pyridines; Retrospective Studies; Triazoles | 2021 |
Isavuconazole: Thermodynamic Evaluation of Processes Sublimation, Dissolution and Partition in Pharmaceutically Relevant Media.
Topics: 1-Octanol; Calorimetry, Differential Scanning; Crystallization; Nitriles; Pyridines; Solubility; Solvents; Temperature; Triazoles; Volatilization; Water | 2021 |
Broad-spectrum azoles and flucloxacillin: a dangerous match.
Topics: Aged; Anti-Bacterial Agents; Antifungal Agents; Aspergillosis; Aspergillus fumigatus; Azoles; Drug Interactions; Drug Therapy, Combination; Female; Floxacillin; Humans; Male; Middle Aged; Nitriles; Pyridines; Staphylococcal Infections; Staphylococcus aureus; Triazoles; Voriconazole | 2022 |
Economic evaluation of isavuconazole for suspected invasive pulmonary aspergillosis in Canada.
Topics: Antifungal Agents; Aspergillosis; Canada; Cost-Benefit Analysis; Humans; Invasive Pulmonary Aspergillosis; Nitriles; Pyridines; Triazoles; Voriconazole | 2022 |
Interaction between flucloxacillin and azoles: Is isavuconazole next?
Topics: Antifungal Agents; Azoles; Drug Interactions; Floxacillin; Humans; Nitriles; Pyridines; Triazoles; Voriconazole | 2021 |
Azole resistance in Aspergillus fumigatus isolates from respiratory specimens in Lyon University Hospitals, France: prevalence and mechanisms involved.
Topics: Antifungal Agents; Aspergillus fumigatus; Cross-Sectional Studies; Cytochrome P-450 Enzyme System; France; Fungal Proteins; Hospitals, University; Humans; Itraconazole; Microbial Sensitivity Tests; Nitriles; Polymorphism, Single Nucleotide; Promoter Regions, Genetic; Pyridines; Respiratory Tract Infections; Retrospective Studies; Triazoles; Tubulin; Voriconazole | 2021 |
Colon mucormycosis with renal spread resistant to lipid complex amphotericin and isavuconazole treatment in a heart transplant recipient.
Topics: Amphotericin B; Colon; Heart Transplantation; Humans; Lipids; Mucormycosis; Nitriles; Pyridines; Triazoles | 2022 |
Systemic antifungal therapy with isavuconazonium sulfate or other agents in adults with invasive mucormycosis or invasive aspergillosis (non-fumigatus): A multicentre, non-interventional registry study.
Topics: Adult; Antifungal Agents; Aspergillosis; Humans; Invasive Fungal Infections; Mucormycosis; Nitriles; Pyridines; Registries; Triazoles | 2022 |
Intricate isavuconazole therapy of a subcutaneous nodule caused by Alternaria infectoria in a heart transplant recipient.
Topics: Alternaria; Antifungal Agents; Heart Transplantation; Humans; Nitriles; Pyridines; Triazoles | 2022 |
A 67-Year-Old Male Patient With COVID-19 With Worsening Respiratory Function and Acute Kidney Failure.
Topics: Acute Kidney Injury; Aged; Amphotericin B; Antibodies, Monoclonal, Humanized; Antifungal Agents; Atrial Fibrillation; Bronchoscopy; COVID-19; Dexamethasone; Diabetes Mellitus, Type 2; Fatal Outcome; Humans; Leukemia, Lymphocytic, Chronic, B-Cell; Male; Mucormycosis; Nitriles; Obesity; Oxygen Inhalation Therapy; Pulmonary Aspergillosis; Pyridines; Respiration, Artificial; SARS-CoV-2; Smoking; Tomography, X-Ray Computed; Triazoles; Voriconazole | 2022 |
Efficacy and safety of Isavuconazole for the treatment of invasive
Topics: Antifungal Agents; Aspergillosis; COVID-19 Drug Treatment; Delayed Diagnosis; Humans; Nitriles; Pyridines; Triazoles | 2022 |
Safety and Effectiveness of Isavuconazole Treatment for Fungal Infections in Solid Organ Transplant Recipients (ISASOT Study).
Topics: Aged; Antifungal Agents; Aspergillosis; Aspergillus; Female; Humans; Male; Middle Aged; Mycoses; Nitriles; Organ Transplantation; Pyridines; Transplant Recipients; Triazoles | 2022 |
Enteral feeding tube administration with therapeutic drug monitoring of crushed posaconazole tablets and opened isavuconazonium sulfate capsules.
Topics: Administration, Oral; Antifungal Agents; Capsules; Drug Monitoring; Enteral Nutrition; Humans; Nitriles; Pyridines; Retrospective Studies; Suspensions; Tablets; Triazoles | 2022 |
Comparison of Mold Active Triazoles as Primary Antifungal Prophylaxis in Patients With Newly Diagnosed Acute Myeloid Leukemia in the Era of Molecularly Targeted Therapies.
Topics: Adult; Antifungal Agents; Azoles; Chemical and Drug Induced Liver Injury; Echinocandins; Fungi; Humans; Invasive Fungal Infections; Leukemia, Myeloid, Acute; Molecular Targeted Therapy; Retrospective Studies; Triazoles; Voriconazole | 2022 |
Real-World Comparison of Isavuconazole and Voriconazole in Terms of the Need for Dosage Adjustments Guided by Clinical Pharmacological Advice During Primary Prophylaxis of Invasive Fungal Infections in Pediatric Patients with Hemato-Oncological Malignanci
Topics: Antifungal Agents; Azoles; Child; Humans; Invasive Fungal Infections; Neoplasms; Nitriles; Pyridines; Retrospective Studies; Triazoles; Voriconazole | 2022 |
Decreased isavuconazole trough concentrations in the treatment of invasive aspergillosis in an adult patient receiving extracorporeal membrane oxygenation support.
Topics: Adult; Aspergillosis; Extracorporeal Membrane Oxygenation; Humans; Invasive Fungal Infections; Male; Middle Aged; Nitriles; Pyridines; Respiratory Insufficiency; Triazoles | 2022 |
A Pharmacokinetic Bioequivalence Study Comparing Different-Strength and -Size Capsules of Isavuconazonium Sulfate in Healthy Japanese Subjects.
Topics: Adolescent; Adult; Child; Humans; Japan; Male; Nitriles; Pyridines; Therapeutic Equivalency; Triazoles | 2022 |
Posaconazole or isavuconazole as sole or predominant antifungal therapy for COVID-19-associated mucormycosis. A retrospective observational case series.
Topics: Antifungal Agents; COVID-19; COVID-19 Drug Treatment; Humans; Mucormycosis; Nitriles; Pyridines; Retrospective Studies; Triazoles | 2022 |
Topics: Antifungal Agents; Candida; Candida albicans; Candida glabrata; Colistin; Microbial Sensitivity Tests; Nitriles; Pyridines; Triazoles | 2022 |
Pharmacokinetics of isavuconazole in healthy cats after oral and intravenous administration.
Topics: Administration, Intravenous; Administration, Oral; Animals; Area Under Curve; Biological Availability; Cats; Half-Life; Humans; Nitriles; Pyridines; Triazoles | 2022 |
Successful isavuconazole salvage therapy for cerebral mucormycosis in a child with relapsed leukemia: A light in the dark tunnel.
Topics: Antifungal Agents; Child; Humans; Leukemia; Mucormycosis; Nitriles; Salvage Therapy; Triazoles | 2023 |
Isavuconazole plasma concentrations in critically ill patients during extracorporeal membrane oxygenation.
Topics: COVID-19; Critical Illness; Extracorporeal Membrane Oxygenation; Humans; Nitriles; Pyridines; Triazoles | 2022 |
The impact of extracorporeal membrane oxygenation on the exposure to isavuconazole: a plea for thorough pharmacokinetic evaluation.
Topics: Extracorporeal Membrane Oxygenation; Humans; Nitriles; Pyridines; Triazoles | 2022 |
Comment on: Isavuconazole plasma concentrations in critically ill patients during extracorporeal membrane oxygenation.
Topics: Critical Illness; Extracorporeal Membrane Oxygenation; Humans; Nitriles; Triazoles | 2022 |
Isavuconazole plasma concentrations in critically ill patients during extracorporeal membrane oxygenation-authors' response.
Topics: Critical Illness; Extracorporeal Membrane Oxygenation; Humans; Nitriles; Triazoles | 2022 |
Isavuconazole for the Treatment of Invasive Mold Disease in Solid Organ Transplant Recipients: A Multicenter Study on Efficacy and Safety in Real-life Clinical Practice.
Topics: Adult; Antifungal Agents; Aspergillosis; Fungi; Humans; Invasive Fungal Infections; Mucormycosis; Nitriles; Organ Transplantation; Retrospective Studies; Tacrolimus; Transplant Recipients; Triazoles | 2023 |
Effect of Isavuconazonium Sulfate and Posaconazole Delayed Release Tablets on Tacrolimus Dose-to-Concentration Ratios.
Topics: Antifungal Agents; Humans; Tablets; Tacrolimus; Triazoles | 2023 |
Health economic analysis of patients treated with isavuconazole in a German comprehensive cancer centre.
Topics: Antifungal Agents; Aspergillosis; Humans; Invasive Fungal Infections; Neoplasms; Nitriles; Triazoles | 2023 |
In vitro activity of isavuconazole against clinically relevant Trichosporon species: a comparative evaluation of EUCAST broth microdilution and MIC Test Strip methods.
Topics: Antifungal Agents; Fluconazole; Microbial Sensitivity Tests; Triazoles; Trichosporon; Voriconazole | 2023 |
Isavuconazole dosing in Asian patients with invasive mould infections: is there a role for therapeutic drug monitoring?
Topics: Antifungal Agents; Drug Monitoring; Fungi; Humans; Nitriles; Triazoles | 2023 |
Population Pharmacokinetics, Exposure-Safety, and Probability of Target Attainment Analyses for Isavuconazole in Japanese Patients With Deep-Seated Mycoses.
Topics: Animals; East Asian People; Humans; Mice; Mycoses; Probability; Triazoles | 2023 |
Comparison of in vitro activities of newer triazoles and classic antifungal agents against dermatophyte species isolated from Iranian University Hospitals: a multi-central study.
Topics: Antifungal Agents; Arthrodermataceae; Caspofungin; Fluconazole; Griseofulvin; Hospitals, University; Humans; Iran; Itraconazole; Terbinafine; Triazoles | 2023 |
Isavuconazole as an alternative for antifungal prophylaxis in patients with hematological malignancies: Is the signal sufficient to support clinical practice?
Topics: Antifungal Agents; Hematologic Neoplasms; Humans; Nitriles; Triazoles | 2023 |
Isavuconazole in the Treatment of Chronic Forms of Coccidioidomycosis.
Topics: Antifungal Agents; Coccidioides; Coccidioidomycosis; Humans; Triazoles | 2023 |
Context of instauration and evolution under isavuconazole, a 2-year prospective real-life study.
Topics: Animals; Antifungal Agents; Aspergillosis; Invasive Fungal Infections; Mucormycosis; Prospective Studies; Triazoles | 2023 |
A Hybrid Algorithm Combining Population Pharmacokinetic and Machine Learning for Isavuconazole Exposure Prediction.
Topics: Algorithms; Bayes Theorem; Models, Biological; Pyridines; Triazoles | 2023 |
Post-hoc analysis of the safety and efficacy of isavuconazole in older patients with invasive fungal disease from the VITAL and SECURE studies.
Topics: Aged; Antifungal Agents; Aspergillosis; Humans; Invasive Fungal Infections; Nitriles; Prospective Studies; Triazoles; Voriconazole | 2023 |
Disseminated histoplasmosis in an immunosuppressed patient successfully treated with isavuconazole.
Topics: Histoplasmosis; Humans; Itraconazole; Male; Nitriles; Triazoles | 2023 |
Isavuconazole-tacrolimus drug-drug interactions in HSCT patients.
Topics: Antifungal Agents; Drug Interactions; Hematopoietic Stem Cell Transplantation; Humans; Immunosuppressive Agents; Tacrolimus; Triazoles | 2023 |
Bronchopulmonary penetration of isavuconazole in lung transplant recipients.
Topics: Bronchoalveolar Lavage Fluid; Humans; Lung; Transplant Recipients; Triazoles | 2023 |
Population Pharmacokinetics of Total and Unbound Isavuconazole in Critically Ill Patients: Implications for Adaptive Dosing Strategies.
Topics: Adult; Anti-Bacterial Agents; Critical Illness; Humans; Prospective Studies; Triazoles | 2023 |
High Variability in Isavuconazole Unbound Fraction in Clinical Practice: A Call to Reconsider Pharmacokinetic/Pharmacodynamic Targets and Breakpoints.
Topics: Humans; Nitriles; Protein Binding; Pyridines; Triazoles | 2023 |