triazoles has been researched along with indomethacin in 74 studies
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 7 (9.46) | 18.7374 |
1990's | 47 (63.51) | 18.2507 |
2000's | 14 (18.92) | 29.6817 |
2010's | 6 (8.11) | 24.3611 |
2020's | 0 (0.00) | 2.80 |
Authors | Studies |
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Giessler, C; Mentz, G; Mentz, P; Mest, HJ | 1 |
de Lima, WT; Jancar, S; Sirois, P | 1 |
Dodam, JR; Johnson, LW; Kruse-Elliott, KT; Olson, NC | 1 |
Shankar, G; Stern, PH | 1 |
Abraham, WM; Ahmed, T; Mansour, E | 1 |
Biagi, G; Dell'Omodarme, G; Di Bussolo, V; Giorgi, I; Livi, O; Scartoni, V | 1 |
Corfield, DR; Webber, SE; Widdicombe, JG | 1 |
Gall, DG; MacNaughton, WK | 1 |
Clark, JE; Harder, DR; Kauser, K; Ma, YH; Masters, BS; Ortiz de Montellano, PR; Roman, RJ | 1 |
Ban, C; Hasegawa, M; Ihara, Y; Inamori, K; Itoh, H; Li, XM; Mori, T; Okagaki, A; Sagawa, N | 1 |
Bonne, C; Meynier, F; Muller, A | 1 |
Hirasawa, N; Mue, S; Ohuchi, K; Omata, M; Tsurufuji, S; Watanabe, M; Yagi, M | 1 |
Barnes, PJ; Belvisi, MG; Stretton, CD | 1 |
Antunes, E; Cirino, G; de Nucci, G; Levi, S; Mariano, M | 1 |
Evans, RW; Kochanek, PM; Magargee, MJ; Melick, JA; Nemoto, EM; Schoettle, RJ | 2 |
Egan, RW; Fernandez, X; Gulbenkian, AR; Kreutner, W; Kung, T; Minnicozzi, M; Watnick, AS | 1 |
Biagi, G; Dell'Omodarme, G; Ferretti, M; Giorgi, I; Livi, O; Scartoni, V; Tiscione, E | 1 |
Durham, SK; Selig, WM; Tocker, JE; Welton, AF | 1 |
Conroy, DM; Piper, PJ; Samhoun, MN | 1 |
Piper, PJ; Yaacob, HB | 1 |
Abraham, WM; Garrido, R; Stevenson, JS | 1 |
Petty, AC; Scrutton, MC | 1 |
Dixon, EJ; Page, CP; Robertson, DN; Wilsoncroft, P | 1 |
Biagi, G; Ferretti, M; Livi, O; Lucacchini, A; Mazzoni, M; Scartoni, V | 1 |
Biagi, G; Livi, O; Lucacchini, A; Mazzoni, MR; Scartoni, V | 1 |
Busse, WD; Rochels, R | 1 |
Abdi-Dezfuli, F; Gislason, H; Svanes, K; Sørbye, H; Waldum, HL | 1 |
Emery, DL; McClure, SJ | 1 |
Aibara, S; Mori, M; Tsukada, W | 1 |
Hay, DW; Hubbard, WC; Undem, BJ | 1 |
Hirafuji, M; Shinoda, H | 1 |
Damas, J; Remacle-Volon, G; Sampaio, CA; Souza Pinto, JC | 1 |
Jarvis, JE; Reeves, JJ; Sheehan, MJ; Strong, P | 1 |
Dosen, P; Gerkens, JF; Smith, AJ | 1 |
Dahlén, SE; Jonsson, EW | 1 |
Cury, Y; Jancar, S; Oga, S; Teixeira, CF | 1 |
Anderson, WP; Christy, IJ; Woods, RL | 1 |
Boichot, E; Braquet, P; Lagente, V; Mencia-Huerta, JM | 1 |
Johnson, LW; Kruse-Elliott, KT; Olson, NC | 1 |
Buxton, DB; Halvorsen, O; Olson, MS; Zhou, W | 1 |
Clayton, NM; Oakley, I; Strong, P; Trevethick, MA | 1 |
Clayton, NM; Oakley, I; Trevethick, MA; Williams, LV | 1 |
Araújo, CV; Cordeiro, RS; Estato, V; Lopes-Martins, RA; Moreira, S; Tibiriçá, EV | 1 |
Asano, K; Bitoh, H; Imaki, H; Kurokawa, K; Nakao, A; Nosaka, K; Shimizu, T; Suzuki, T; Taniguchi, S; Watanabe, T | 1 |
Desouza, IA; Ribeiro-DaSilva, G | 1 |
Fukuchi, Y; Ishii, S; Katayama, H; Nagase, T; Ouchi, Y; Shimizu, T | 1 |
Shirasawa, E; Tsuji, F | 1 |
Ibbotson, G; Kubes, P; Scott, RB; Withers, GD | 1 |
Bast, A; Buurman, WA; Kramer, K; Pennings, HJ; Wouters, EF | 1 |
Jancar, S; Steil, AA; Tavares de Lima, W | 1 |
Ichinowatari, G; Ohuchi, K; Tanimoto, A; Yaginuma, H; Yamada, M | 1 |
Alloatti, G; Camussi, G; De Martino, A; Montrucchio, G; Penna, C | 1 |
Fonteles, MC; Monteiro, A; Serra, H | 1 |
Domont, GB; Frutuoso, VS; Martins, MA; Moussatché, H; Perales, J; Rocha, SL | 1 |
Saxena, NC | 1 |
Cho, W; Fujimura, M; Kim, KP; Kita, T; Kurashima, K; Leff, AR; Munoz, NM; Myou, S; Nakao, S; Nonomura, A; Sano, H; Shioya, T; Zhu, X | 1 |
Chiribiri, A; Gattullo, D; Pagliaro, P; Paolocci, N; Penna, C; Rastaldo, R | 1 |
Ichinowatari, G; Ohuchi, K; Tanimoto, A; Tsuyuki, K; Yaginuma, H; Yamada, M | 1 |
Bril, A; Broadley, KJ; Khandoudi, N; Maddock, HL | 1 |
Arruda, VA; Bon, C; de Araújo, AL; de Araújo, PM; de Queiroz Guimarães, A; Hyslop, S | 1 |
Ay, I; Tuncer, M | 1 |
Battastini, AM; Bavaresco, L; Bernardi, A; Delgado-Cañedo, A; Jacques-Silva, MC; Lenz, G; Wink, MR | 1 |
Cicha, MZ; Hökfelt, T; Kopp, UC; Mulder, J; Smith, LA | 1 |
Araújo, CV; Figueiredo, MR; Kaplan, MA; Lessa, MA; Pimenta, D; Tibiriçá, E | 1 |
Kalgutkar, AS; Obach, RS; Soglia, JR; Zhao, SX | 1 |
Ansari, HR; Falck, JR; Ledent, C; Mustafa, SJ; Nayeem, MA; Poloyac, SM; Ponnoth, DS; Zeldin, DC | 1 |
Jin, M; Koizumi, S; Linden, J; Odashima, M; Ohnishi, H; Otaka, M; Watanabe, S | 1 |
Chavda, M; Clawson, JS; Edwards, AJ; Pham, TN; Strohmeier, M; Vogt, FG; Watson, SA | 1 |
Ertan, M; Kazkayası, I; Okay, G; Oztürk, Eİ; Sarıgöl, D; Tel, BC; Tozkoparan, B; Uzgören-Baran, A | 1 |
Ahmadi, F; Alipoiur, E; Amini, M; Ghayahbashi, MR; khademi, HR; Ostad, SN; Sharifzadeh, M; Vosooghi, M | 1 |
Randall, MD; Roberts, RE; Wong, PS | 1 |
Aleksza, M; Dobolyi, Á; Juhász, G; Kékesi, KA; Kovács, Z; Lakatos, RK; Todorov, MI | 1 |
Bucci, G; Gillen, M; Kerr, B; Lee, C; Shen, Z; Tieu, K; Wilson, D | 1 |
1 review(s) available for triazoles and indomethacin
Article | Year |
---|---|
Non-steroidal anti-inflammatory drug-induced gastric damage in experimental animals: underlying pathological mechanisms.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Cricetinae; Gastric Acid; Histamine H2 Antagonists; Indomethacin; Pyloric Antrum; Rabbits; Ranitidine; Rats; Stomach Ulcer; Triazoles | 1995 |
73 other study(ies) available for triazoles and indomethacin
Article | Year |
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Interactions of prostanoids with the platelet activating factors.
Topics: 6-Ketoprostaglandin F1 alpha; Animals; Azepines; Guinea Pigs; Heart; Iloprost; In Vitro Techniques; Indomethacin; Myocardial Contraction; Perfusion; Platelet Activating Factor; Prostaglandins; Sulfonamides; Thromboxane A2; Thromboxane B2; Triazoles | 1992 |
Immune-complex alveolitis in the rat: evidence for platelet activating factor and leukotrienes as mediators of the vascular lesions.
Topics: Alveolitis, Extrinsic Allergic; Animals; Azepines; Bronchoalveolar Lavage Fluid; Dinoprostone; Diterpenes; Econazole; Ginkgolides; Hemoglobins; Hemorrhage; Indomethacin; Lactones; Leukotriene B4; Leukotrienes; Lipoxygenase Inhibitors; Male; Platelet Activating Factor; Propionates; Quinolines; Rats; Rats, Inbred Strains; Thromboxanes; Triazoles | 1992 |
Differential effects of WEB 2086 and SRI 63-441 on TNF-alpha-induced alterations in cardiopulmonary function.
Topics: Animals; Azepines; ErbB Receptors; Heart; Indomethacin; Lipids; Lung; Platelet Activating Factor; Platelet Aggregation; Quinolinium Compounds; Swine; Triazoles; Tumor Necrosis Factor-alpha | 1992 |
Interactions of tumor necrosis factor with local and systemic factors in fetal rat limb bones.
Topics: Animals; Azepines; Bone and Bones; Bone Resorption; Culture Techniques; Dexamethasone; Hindlimb; Indomethacin; Interferon-gamma; Interleukin 1 Receptor Antagonist Protein; Interleukin-1; Parathyroid Hormone; Platelet Activating Factor; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Sialoglycoproteins; Transforming Growth Factor beta; Triazoles; Tumor Necrosis Factor-alpha | 1992 |
Attenuation of platelet-activating factor-induced airway responses with methylprednisolone succinate in sheep.
Topics: Airway Resistance; Animals; Azepines; Bronchoconstriction; Carbachol; Eicosanoids; Indomethacin; Methylprednisolone Hemisuccinate; Platelet Activating Factor; Propionates; Quinolines; Respiratory Mechanics; Sheep; SRS-A; Triazoles | 1992 |
An 1,2,3-triazole derivative bioisoster of a potent in vitro prostaglandin synthesis inhibitor: preparation and biological activity.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Cyclooxygenase Inhibitors; Humans; In Vitro Techniques; Indomethacin; Malondialdehyde; Prostaglandin Antagonists; Triazoles | 1992 |
Mechanisms of platelet activating factor-induced changes in sheep tracheal blood flow.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Azepines; Chromones; Cimetidine; Dose-Response Relationship, Drug; Female; Indomethacin; Methacholine Compounds; Muscle Tonus; Muscle, Smooth; Nedocromil; Platelet Activating Factor; Pyrilamine; Quinolones; Regional Blood Flow; Sheep; Trachea; Triazoles; Vascular Resistance | 1991 |
Mechanisms of platelet-activating factor-induced electrolyte transport in the rat jejunum.
Topics: Animals; Arachidonic Acids; Azepines; Biological Transport, Active; Chlorides; Dinoprostone; Eicosanoic Acids; Electrophysiology; Female; Indomethacin; Jejunum; Platelet Activating Factor; Quinacrine; Rats; Triazoles | 1991 |
Inhibitors of cytochrome P-450 attenuate the myogenic response of dog renal arcuate arteries.
Topics: Animals; Blood Pressure; Bridged Bicyclo Compounds, Heterocyclic; Cyclooxygenase Inhibitors; Cytochrome P-450 Enzyme Inhibitors; Dogs; Fatty Acids, Monounsaturated; Fatty Acids, Unsaturated; Hydrazines; Indomethacin; Ketoconazole; Kinetics; Muscle, Smooth, Vascular; Phospholipases A; Phospholipases A2; Phosphorylcholine; Proadifen; Renal Artery; Triazoles | 1991 |
The involvement of platelet-activating factor in thrombocytopenia and follicular rupture during gonadotropin-induced superovulation in immature rats.
Topics: Animals; Azepines; Chorionic Gonadotropin; Female; Gonadotropins, Equine; Indomethacin; Ovulation; Ovulation Induction; Platelet Activating Factor; Platelet Activation; Platelet Count; Rats; Rats, Inbred Strains; Superovulation; Thrombocytopenia; Triazoles; Vena Cava, Inferior | 1991 |
PAF-induced conjunctivitis in the rabbit is mediated by peptido-leukotrienes.
Topics: Animals; Azepines; Conjunctiva; Conjunctivitis; Cyclooxygenase Inhibitors; Dicarboxylic Acids; Evans Blue; Extravasation of Diagnostic and Therapeutic Materials; Indomethacin; Leukotriene B4; Leukotrienes; Lipoxygenase Inhibitors; Male; Platelet Activating Factor; Rabbits; Second Messenger Systems; Tetrazoles; Thiazoles; Thienopyridines; Triazoles | 1990 |
Stimulation of neutrophil adherence to vascular endothelial cells by histamine and thrombin and its inhibition by PAF antagonists and dexamethasone.
Topics: Animals; Azepines; Cell Adhesion; Cells, Cultured; Dexamethasone; Endothelium, Vascular; Furans; Histamine; Humans; In Vitro Techniques; Indomethacin; Male; Neutrophils; Phospholipid Ethers; Platelet Activating Factor; Rats; Rats, Inbred Strains; Thrombin; Triazoles | 1991 |
Bombesin-induced bronchoconstriction in the guinea pig: mode of action.
Topics: Animals; Azepines; Blood Pressure; Bombesin; Bronchoconstriction; Dose-Response Relationship, Drug; Guinea Pigs; Indomethacin; Male; Muscle, Smooth; Platelet Activating Factor; Pyrilamine; Trachea; Triazoles | 1991 |
Pharmacological characterization of polycation-induced rat hind-paw oedema.
Topics: 4,5-Dihydro-1-(3-(trifluoromethyl)phenyl)-1H-pyrazol-3-amine; Animals; Arginine; Azepines; Dexamethasone; Edema; Evans Blue; Heparin; Histamine; Indomethacin; Male; omega-N-Methylarginine; Peptides; Polylysine; Rats; Rats, Inbred Strains; Serotonin; Triazoles | 1990 |
Platelet activating factor antagonists do not alter normal cerebral blood flow or cerebral oxygen consumption.
Topics: Animals; Azepines; Brain; Cerebrovascular Circulation; Diterpenes; Ginkgolides; Indomethacin; Lactones; Male; Oxygen Consumption; Platelet Activating Factor; Rats; Rats, Inbred Strains; Triazoles | 1990 |
Anaphylactic challenge causes eosinophil accumulation in bronchoalveolar lavage fluid of guinea pigs. Modulation by betamethasone, phenidone, indomethacin, WEB 2086, and a novel antiallergy agent, SCH 37224.
Topics: Albumins; Anaphylaxis; Animals; Asthma; Azepines; Betamethasone; Bronchoalveolar Lavage Fluid; Cell Count; Eosinophils; Guinea Pigs; Histamine; Immunization; Indomethacin; Leukotriene Antagonists; Lipoxygenase Inhibitors; Lung; Male; Naphthyridines; Ovalbumin; Platelet Activating Factor; Pyrazoles; Thromboxanes; Triazoles | 1990 |
Studies on 1,2,3-triazole derivatives as in vitro inhibitors of prostaglandin synthesis.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Arachidonic Acid; Arachidonic Acids; Aspirin; Blood Platelets; Humans; In Vitro Techniques; Indomethacin; Malondialdehyde; Prostaglandin Antagonists; Triazoles | 1990 |
Phospholipase A2-induced pulmonary and hemodynamic responses in the guinea pig. Effects of enzyme inhibitors and mediators antagonists.
Topics: Animals; Azepines; Blood Pressure; Bronchi; Bronchoalveolar Lavage Fluid; Dexamethasone; Enzyme Inhibitors; Guinea Pigs; Humans; Indazoles; Indomethacin; Lung; Male; Phospholipases A; Phospholipases A2; Platelet Activating Factor; Pressure; Propranolol; Pyrilamine; SRS-A; Trachea; Triazoles | 1990 |
Relaxations of guinea-pig isolated trachea induced by platelet-activating factor are epithelial-dependent and are antagonised by WEB 2086.
Topics: Albuterol; Animals; Azepines; Epithelium; Guinea Pigs; In Vitro Techniques; Indomethacin; Male; Muscle Relaxation; Muscle, Smooth; Platelet Activating Factor; Trachea; Triazoles | 1990 |
Endogenous platelet activating factor does not modulate blood flow and metabolism in normal rat brain.
Topics: Animals; Azepines; Blood Pressure; Brain; Cerebrovascular Circulation; Diterpenes; Ginkgolides; Indomethacin; Lactones; Male; Oxygen; Platelet Activating Factor; Rats; Rats, Inbred Strains; Reference Values; Triazines; Triazoles | 1990 |
Interactions of platelet activating factor, thromboxane A2 and leukotrienes in guinea-pig heart.
Topics: Anaphylaxis; Animals; Azepines; Cyclooxygenase Inhibitors; Guinea Pigs; Heart; In Vitro Techniques; Indomethacin; Leukotrienes; Lipoxygenase Inhibitors; Naphthoquinones; ortho-Aminobenzoates; Platelet Activating Factor; Thromboxane A2; Triazines; Triazoles | 1989 |
A possible role for PAF in allergen-induced late responses: modification by a selective antagonist.
Topics: Aerosols; Allergens; Animals; Antigens, Helminth; Ascaris; Asthma; Azepines; Chlorpheniramine; Chromones; Disease Models, Animal; Hypersensitivity, Delayed; Hypersensitivity, Immediate; Indomethacin; Lung; Platelet Activating Factor; Reference Values; Sheep; SRS-A; Triazines; Triazoles | 1989 |
Platelet aggregation in whole blood: is the response to adrenaline, 5-hydroxytryptamine and PAF a direct consequence of stimulation by these agonists?
Topics: Apyrase; Azepines; Cell Count; Dioxanes; Dose-Response Relationship, Drug; Epinephrine; Hirudins; Humans; Idazoxan; Indomethacin; Ketanserin; Platelet Activating Factor; Platelet Aggregation; Serotonin; Triazines; Triazoles | 1989 |
The effect of Paf antagonists on bronchial hyperresponsiveness induced by Paf, propranolol or indomethacin.
Topics: Acetylcholine; Animals; Azepines; Bronchi; Diterpenes; Ginkgolides; Guinea Pigs; Histamine; In Vitro Techniques; Indomethacin; Lactones; Male; Phospholipid Ethers; Platelet Activating Factor; Propranolol; Respiratory Hypersensitivity; Triazines; Triazoles | 1989 |
4-Benzoyl- and 4-benzyl-1,2,3-triazol-N-acetic acids, in vitro inhibitors of the prostaglandin synthesis.
Topics: Animals; Anti-Inflammatory Agents; Benzyl Compounds; Binding, Competitive; Cattle; Chemical Phenomena; Chemistry; Exocrine Glands; In Vitro Techniques; Indomethacin; Magnetic Resonance Spectroscopy; Microsomes; Prostaglandin Antagonists; Prostaglandins; Triazoles | 1986 |
N-benzyl-4-phenyl-1,2,3-triazole derivatives as in vitro inhibitors of the prostaglandin synthesis.
Topics: Animals; Anti-Inflammatory Agents; Benzyl Compounds; Binding, Competitive; Cattle; Chemical Phenomena; Chemistry; In Vitro Techniques; Indomethacin; Magnetic Resonance Spectroscopy; Male; Malondialdehyde; Microsomes; Muscle, Smooth, Vascular; Prostaglandin Antagonists; Triazoles | 1986 |
[Experimental studies on the effect of prostaglandin and leukotriene synthesis inhibitors on epithelial regeneration of the cornea].
Topics: Animals; Anti-Inflammatory Agents; Benzenesulfonates; Chemotaxis, Leukocyte; Cornea; Corneal Injuries; Epithelium; Female; Indomethacin; Leukotriene B4; Lipoxygenase Inhibitors; Male; Prostaglandin Antagonists; Rabbits; Regeneration; Triazoles; Wound Healing | 1983 |
Role of prostaglandins and histamine in hyperemic response to superficial and deep gastric mucosal injury and H+ back-diffusion in cats.
Topics: 6-Ketoprostaglandin F1 alpha; Animals; Astemizole; Cats; Dinoprostone; Gastric Acid; Gastric Mucosa; Histamine; Histamine H2 Antagonists; Hyperemia; Indomethacin; Male; Prostaglandins; Regional Blood Flow; Saline Solution, Hypertonic; Triazoles | 1995 |
Studies on the inhibition of rejection of Trichostrongylus colubriformis larvae from immune sheep.
Topics: Animals; Azepines; Chlorpheniramine; Cyclosporine; Dexamethasone; Indomethacin; Larva; Piroxicam; Rejection, Psychology; Sheep; Sheep Diseases; Theophylline; Triazoles; Trichostrongylosis; Trichostrongylus | 1995 |
Inhibitory effect of DS-4574 on leukotriene- or antigen-induced bronchoconstriction in guinea pigs.
Topics: Animals; Antigens; Asthma; Atropine; Bronchoconstriction; Guinea Pigs; Histamine Release; Immunization; Indomethacin; Leukotriene Antagonists; Leukotriene E4; Male; Pyrilamine; Pyrimidines; SRS-A; Triazoles | 1993 |
Endothelin-induced contraction and mediator release in human bronchus.
Topics: Acetylcholine; Azepines; Bridged Bicyclo Compounds, Heterocyclic; Bronchi; Dicarboxylic Acids; Endothelins; Fatty Acids, Unsaturated; Histamine Release; Humans; Hydrazines; In Vitro Techniques; Indomethacin; Inflammation; Leukotrienes; Lung; Meclofenamic Acid; Muscle Contraction; Muscle, Smooth; Platelet Aggregation Inhibitors; Prostaglandins; Spectrometry, Fluorescence; SRS-A; Thromboxane A2; Triazoles | 1993 |
Increased prostaglandin I2 and thromboxane A2 production by rat dental pulp after intravenous administration of endotoxin.
Topics: Animals; Arachidonic Acid; Azepines; Dental Pulp; Endotoxins; Epoprostenol; Escherichia coli; Indomethacin; Injections, Intravenous; Jejunum; Lung; Male; Platelet Activating Factor; Rats; Rats, Wistar; Thromboxane A2; Time Factors; Triazoles | 1994 |
Collagenase-induced oedema in the rat paw and the kinin system.
Topics: Animals; Arginine; Azepines; Bradykinin; Collagenases; Edema; Female; Heparin; Hindlimb; Indomethacin; Kallikrein-Kinin System; Ketoprofen; Kininogens; Male; Methysergide; Nitroarginine; Platelet Aggregation Inhibitors; Pyrilamine; Rats; Rats, Wistar; Serine Proteinase Inhibitors; Triazoles | 1995 |
Further investigations into adenosine A1 receptor-mediated contraction in rat colonic muscularis mucosae and its augmentation by certain alkylxanthine antagonists.
Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Colon; Cyclooxygenase Inhibitors; In Vitro Techniques; Indomethacin; Intestinal Mucosa; Muscle Contraction; Muscle, Smooth; Phosphodiesterase Inhibitors; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Quinazolines; Rats; Theophylline; Triazoles; Vasodilator Agents; Xanthines | 1995 |
WEB-2086 and indomethacin do not modify blood pressure fall on unclipping hypertensive rats.
Topics: Animals; Azepines; Blood Pressure; Disease Models, Animal; Hypertension, Renal; Indomethacin; Injections, Intravenous; Male; Platelet Activating Factor; Rats; Rats, Wistar; Renal Artery; Triazoles | 1994 |
Interactions between leukotrienes and histamine in the anaphylactic contraction of guinea pig lung parenchyma.
Topics: Anaphylaxis; Animals; Azepines; Guinea Pigs; Histamine; In Vitro Techniques; Indoles; Indomethacin; Leukotriene Antagonists; Leukotrienes; Lung; Male; Muscle Contraction; Ovalbumin; Platelet Activating Factor; Quinolines; Triazoles | 1994 |
Hyperalgesia induced by Bothrops jararaca venom in rats: role of eicosanoids and platelet activating factor (PAF).
Topics: Animals; Azepines; Bothrops; Crotalid Venoms; Dexamethasone; Diterpenes; Dose-Response Relationship, Drug; Eicosanoids; Fibrinolytic Agents; Ginkgolides; Hyperalgesia; Indomethacin; Lactones; Male; Platelet Activating Factor; Rats; Rats, Wistar; Triazoles | 1994 |
Mediators of the hypotensive response to increased renal perfusion in rabbits.
Topics: Animals; Azepines; Blood Pressure; Diuresis; Enalaprilat; Hemodynamics; Hypotension; Indomethacin; Natriuresis; Perfusion; Platelet Activating Factor; Pressure; Rabbits; Renal Circulation; Triazoles | 1993 |
Bronchopulmonary responses to endothelin-1 in sensitized and challenged guinea-pigs: role of cyclooxygenase metabolites and platelet-activating factor.
Topics: Aerosols; Animals; Azepines; Bronchi; Disease Models, Animal; Endothelins; Glycopeptides; Guinea Pigs; Immunization; Indomethacin; Lung; Male; Neprilysin; Ovalbumin; Platelet Activating Factor; Prostaglandin-Endoperoxide Synthases; Respiratory Function Tests; Tetrazoles; Thienopyridines; Time Factors; Triazoles | 1993 |
Effect of 5-lipoxygenase and cyclooxygenase blockade on porcine hemodynamics during continuous infusion of platelet-activating factor.
Topics: 6-Ketoprostaglandin F1 alpha; Animals; Azepines; Blood; Calcimycin; Chromatography, High Pressure Liquid; Cyclooxygenase Inhibitors; Hemodynamics; Hypertension, Pulmonary; In Vitro Techniques; Indomethacin; Infusions, Intra-Arterial; Leukotriene B4; Lipoxygenase Inhibitors; Naphthoquinones; ortho-Aminobenzoates; Platelet Activating Factor; Swine; Thromboxane B2; Triazoles | 1993 |
Glycogenolytic and haemodynamic responses to bovine serum albumin in isolated perfused livers from sensitized rats.
Topics: Animals; Azepines; Calcium; Glycogen; Hemodynamics; Ibuprofen; In Vitro Techniques; Indomethacin; Lactates; Lactic Acid; Liver; Male; Perfusion; Pyruvates; Pyruvic Acid; Rats; Rats, Sprague-Dawley; Serum Albumin, Bovine; Triazoles | 1993 |
The role of acid in the pathogenesis of indomethacin-induced gastric antral ulcers in the rat.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Anti-Ulcer Agents; Cimetidine; Female; Gastric Acid; Histamine H2 Antagonists; Hydrochloric Acid; Indomethacin; Pyloric Antrum; Ranitidine; Rats; Stomach Ulcer; Triazoles | 1996 |
Platelet-activating factor. A possible role in the modulation of the vasomotor tone and blood pressure.
Topics: Adrenergic alpha-Agonists; Animals; Anti-Inflammatory Agents, Non-Steroidal; Azepines; Blood Pressure; Carotid Arteries; Diterpenes; Enzyme Inhibitors; Ginkgolides; Indomethacin; Lactones; Muscle Tonus; Muscle, Smooth, Vascular; Norepinephrine; Phospholipases A; Platelet Activating Factor; Platelet Aggregation Inhibitors; Quinacrine; Rabbits; Triazoles | 1996 |
cAMP mediates homologous downregulation of PAF receptor mRNA expression in mesangial cells.
Topics: Animals; Azepines; Cyclic AMP; Cyclooxygenase Inhibitors; Dinoprostone; Down-Regulation; Female; Glomerular Mesangium; Indomethacin; Kinetics; Platelet Activating Factor; Platelet Membrane Glycoproteins; Rats; Rats, Sprague-Dawley; Receptors, Cell Surface; Receptors, G-Protein-Coupled; RNA, Messenger; Signal Transduction; Transcription, Genetic; Triazoles; Virulence Factors, Bordetella | 1997 |
The pharmacological profile of mouse hind paw inflammation induced by staphylococcal enterotoxin type A.
Topics: 4,5-Dihydro-1-(3-(trifluoromethyl)phenyl)-1H-pyrazol-3-amine; Animals; Azepines; Capsaicin; Cimetidine; Dexamethasone; Diphenhydramine; Edema; Enterotoxins; Enzyme Inhibitors; Hindlimb; Histamine Antagonists; Indomethacin; Inflammation; Male; Mice; Platelet Aggregation Inhibitors; Triazoles | 1997 |
Airway responsiveness in transgenic mice overexpressing platelet-activating factor receptor. Roles of thromboxanes and leukotrienes.
Topics: Animals; Azepines; Bronchi; Bronchial Hyperreactivity; Chromones; Indoles; Indomethacin; Leukotriene Antagonists; Leukotrienes; Lipoxygenase Inhibitors; Lung; Methacrylates; Mice; Mice, Transgenic; Phenylpropionates; Platelet Activating Factor; Platelet Membrane Glycoproteins; Receptors, Cell Surface; Receptors, G-Protein-Coupled; Receptors, Leukotriene B4; Thromboxanes; Triazoles | 1997 |
The role of platelet-activating factor in cell infiltration in endotoxin-induced uveitis in guinea pigs.
Topics: Animals; Anterior Chamber; Aqueous Humor; Azepines; Betamethasone; Chemotaxis, Leukocyte; Dinoprostone; Escherichia coli; Flow Cytometry; Guinea Pigs; Indomethacin; Leukocyte Count; Leukocytes; Lipopolysaccharides; Male; Ophthalmic Solutions; Platelet Activating Factor; Platelet Aggregation Inhibitors; Triazoles; Uveitis, Anterior | 1998 |
Anaphylaxis-induced mesenteric vascular permeability, granulocyte adhesion, and platelet aggregates in rat.
Topics: Albuterol; Anaphylaxis; Animals; Azepines; Capillary Permeability; Cell Adhesion; Diphenhydramine; Granulocytes; Immunoglobulin E; Indomethacin; Mast Cells; Methysergide; Microscopy, Video; Ovalbumin; Platelet Aggregation; Platelet Aggregation Inhibitors; Rats; Serum Albumin, Bovine; Splanchnic Circulation; Time Factors; Triazoles; Venules | 1998 |
Tumour necrosis factor-alpha induces hyperreactivity in tracheal smooth muscle of the guinea-pig in vitro.
Topics: Airway Resistance; Animals; Azepines; Bronchial Hyperreactivity; Culture Techniques; Dose-Response Relationship, Drug; Guinea Pigs; Indomethacin; Muscle, Smooth; Platelet Activating Factor; Platelet Aggregation Inhibitors; Recombinant Proteins; Triazoles; Tumor Necrosis Factor-alpha | 1998 |
Modulation by lipid mediators of immune complex-induced lung inflammation in mice.
Topics: Animals; Antigen-Antibody Complex; Arthus Reaction; Azepines; Benzopyrans; Blood Vessels; Bronchoalveolar Lavage Fluid; Capillary Permeability; Dose-Response Relationship, Drug; Eicosanoids; Hemoglobins; Immune Complex Diseases; Indoles; Indomethacin; Lipoxygenase Inhibitors; Lung; Male; Mice; Mice, Inbred BALB C; Mice, Inbred C3H; Neutrophils; Peroxidase; Platelet Activating Factor; Platelet Aggregation Inhibitors; Pneumonia; Receptors, Leukotriene B4; Species Specificity; Triazoles | 1998 |
Possible participation of intracellular platelet-activating factor in tumor necrosis factor-alpha production by rat peritoneal macrophages.
Topics: Animals; Azepines; Cells, Cultured; Dinoprostone; Enzyme Inhibitors; Furans; Imidazoles; Indomethacin; Macrophages, Peritoneal; Male; Organophosphorus Compounds; Platelet Activating Factor; Pyridinium Compounds; Rats; Rats, Sprague-Dawley; RNA, Messenger; Thapsigargin; Triazoles; Tumor Necrosis Factor-alpha | 1999 |
Role of nitric oxide and platelet-activating factor in cardiac alterations induced by tumor necrosis factor-alpha in the guinea-pig papillary muscle.
Topics: Action Potentials; Adrenergic beta-Antagonists; Analysis of Variance; Animals; Azepines; Cyclooxygenase Inhibitors; Depression, Chemical; Guinea Pigs; Heart; In Vitro Techniques; Indomethacin; Myocardial Contraction; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Phospholipid Ethers; Platelet Activating Factor; Platelet Aggregation Inhibitors; Propranolol; Triazoles; Tumor Necrosis Factor-alpha | 1999 |
The effect of Bothrops jararaca venom on rat kidney after short-term exposure: preliminary results.
Topics: Animals; Azepines; Bothrops; Crotalid Venoms; Cyclooxygenase Inhibitors; Diterpenes; Fibrinolytic Agents; Ginkgolides; Glomerular Filtration Rate; Indomethacin; Kidney; Lactones; Male; Osmolar Concentration; Potassium; Rats; Rats, Wistar; Sodium; Triazoles | 1999 |
Inhibition of the hyperalgesic activity of Bothrops jararaca venom by an antibothropic fraction isolated from opossum (Didelphis marsupialis) serum.
Topics: Animals; Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non-Steroidal; Antivenins; Azepines; Bothrops; Crotalid Venoms; Dexamethasone; Hyperalgesia; Indomethacin; Opossums; Platelet Aggregation Inhibitors; Triazoles | 2000 |
Inhibition of GABA(A) receptor (GABAR) currents by arachidonic acid in HEK 293 cells stably transfected with alpha1beta2gamma2 GABAR subunits.
Topics: 5,8,11,14-Eicosatetraynoic Acid; Anticonvulsants; Arachidonic Acid; Binding, Competitive; Cells, Cultured; Cyclooxygenase Inhibitors; Diazepam; Dose-Response Relationship, Drug; Fatty Acids; Fatty Acids, Monounsaturated; GABA Antagonists; GABA Modulators; GABA-A Receptor Antagonists; gamma-Aminobutyric Acid; Humans; Indomethacin; Kidney; Linoleic Acid; Masoprocol; Membrane Potentials; Patch-Clamp Techniques; Pentobarbital; Picrotoxin; Receptors, GABA-A; Recombinant Proteins; Transfection; Triazoles | 2000 |
Blockade of eosinophil migration and airway hyperresponsiveness by cPLA2-inhibition.
Topics: Animals; Antigens; Azepines; Benzoquinones; Bronchoconstriction; Butyrophenones; Eicosapentaenoic Acid; Enzyme Inhibitors; Eosinophils; Guinea Pigs; Indomethacin; Male; Methacholine Chloride; Phospholipases A; Phospholipases A2; Piperidines; Respiratory Hypersensitivity; Triazoles | 2001 |
Cytochrome P-450 metabolite of arachidonic acid mediates bradykinin-induced negative inotropic effect.
Topics: 8,11,14-Eicosatrienoic Acid; Animals; Arachidonic Acid; Blood Pressure; Bradykinin; Coronary Vessels; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Endothelium, Vascular; Enzyme Inhibitors; Heart; Heart Rate; In Vitro Techniques; Indomethacin; Male; Myocardium; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Octoxynol; Proadifen; Rats; Rats, Wistar; Tachyphylaxis; Triazoles; Ventricular Function, Left | 2001 |
Participation of prostaglandin E2 and platelet-activating factor in thapsigargin-induced production of interleukin-6.
Topics: Acetyltransferases; Acyl-Carrier Protein S-Acetyltransferase; Animals; Azepines; Cells, Cultured; Dinoprostone; Dose-Response Relationship, Drug; Drug Synergism; Enzyme Inhibitors; Furans; Imidazoles; Indomethacin; Interleukin-6; Macrophages, Peritoneal; Male; Organophosphorus Compounds; Platelet Activating Factor; Platelet Membrane Glycoproteins; Rats; Rats, Sprague-Dawley; Receptors, Cell Surface; Receptors, G-Protein-Coupled; RNA, Messenger; Thapsigargin; Triazoles | 2002 |
Effects of adenosine receptor agonists on guinea-pig isolated working hearts and the role of endothelium and NO.
Topics: Adenosine; Animals; Cyclooxygenase Inhibitors; Endothelium, Vascular; Guinea Pigs; Heart; Hemodynamics; In Vitro Techniques; Indomethacin; Male; Nitric Oxide; Nitric Oxide Synthase; Phenethylamines; Prostaglandins; Purinergic P1 Receptor Agonists; Triazines; Triazoles | 2002 |
Bothrops lanceolatus (Fer de lance) venom stimulates leukocyte migration into the peritoneal cavity of mice.
Topics: Animals; Azepines; Benzoquinones; Bothrops; Cell Migration Inhibition; Crotalid Venoms; Dexamethasone; Dose-Response Relationship, Drug; Indomethacin; Injections, Intraperitoneal; Macrophages; Male; Mice; Mice, Inbred BALB C; Neutrophils; Phospholipases A; Triazoles | 2003 |
Both endothelium and afferent nerve endings play a role in acetylcholine-induced renal vasodilation.
Topics: Acetylcholine; Animals; Calcitonin Gene-Related Peptide; Capsaicin; Cyclic AMP-Dependent Protein Kinases; Cyclooxygenase Inhibitors; Endothelium, Vascular; Enzyme Inhibitors; Female; Glycyrrhetinic Acid; Indomethacin; Male; Nerve Endings; Neurons, Afferent; Nitric Oxide; Nitric Oxide Synthase Type III; Nitroarginine; Octoxynol; Rats; Rats, Wistar; Renal Circulation; Second Messenger Systems; Triazines; Triazoles; Vasodilator Agents | 2006 |
Indomethacin stimulates activity and expression of ecto-5'-nucleotidase/CD73 in glioma cell lines.
Topics: 5'-Nucleotidase; Actins; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Anti-Inflammatory Agents, Non-Steroidal; Cell Line, Tumor; Cell Proliferation; Dimethyl Sulfoxide; Dose-Response Relationship, Drug; Enzyme Activation; Flow Cytometry; Gene Expression Regulation, Enzymologic; Glioma; Humans; Indomethacin; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Quinazolines; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Theophylline; Time Factors; Triazoles; Xanthines | 2007 |
Renal sympathetic nerve activity modulates afferent renal nerve activity by PGE2-dependent activation of alpha1- and alpha2-adrenoceptors on renal sensory nerve fibers.
Topics: Adrenergic alpha-1 Receptor Antagonists; Adrenergic alpha-2 Receptor Antagonists; Adrenergic Fibers; Animals; Calcitonin Gene-Related Peptide; Dinoprostone; Indomethacin; Kidney; Male; Neurons, Afferent; Neurons, Efferent; Norepinephrine; Norepinephrine Plasma Membrane Transport Proteins; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, alpha-1; Receptors, Adrenergic, alpha-2; Receptors, Prostaglandin E; Receptors, Prostaglandin E, EP4 Subtype; Substance P; Thiophenes; Triazoles | 2007 |
Antihypertensive effects of crude extracts from leaves of Echinodorus grandiflorus.
Topics: Adrenergic beta-Antagonists; Alismataceae; Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensive Agents; Atenolol; Azepines; Blood Pressure; Bradykinin; Brazil; Cyclooxygenase Inhibitors; Enalapril; Hemodynamics; Indomethacin; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Phytotherapy; Plant Extracts; Plant Leaves; Platelet Membrane Glycoproteins; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Receptors, G-Protein-Coupled; Triazoles | 2008 |
Can in vitro metabolism-dependent covalent binding data in liver microsomes distinguish hepatotoxic from nonhepatotoxic drugs? An analysis of 18 drugs with consideration of intrinsic clearance and daily dose.
Topics: Acetaminophen; Binding Sites; Buspirone; Carbamazepine; Diclofenac; Diphenhydramine; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Hepatocytes; Humans; Indomethacin; Meloxicam; Microsomes, Liver; Molecular Structure; Paroxetine; Piperazines; Propranolol; Raloxifene Hydrochloride; Simvastatin; Structure-Activity Relationship; Thiazines; Thiazoles; Ticrynafen; Toxicity Tests; Triazoles | 2008 |
Role of CYP epoxygenases in A2A AR-mediated relaxation using A2A AR-null and wild-type mice.
Topics: 8,11,14-Eicosatrienoic Acid; Acetylcholine; Adenosine; Adenosine-5'-(N-ethylcarboxamide); Amides; Amidines; Animals; Aorta; Arachidonic Acid; Chromatography, Liquid; Cytochrome P-450 CYP4A; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Cytochrome P450 Family 2; Dose-Response Relationship, Drug; Enzyme Inhibitors; Indomethacin; Male; Mice; Mice, Knockout; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Phenethylamines; Prostaglandin-Endoperoxide Synthases; Pyrimidines; Receptor, Adenosine A2A; Tandem Mass Spectrometry; Triazoles; Vasoconstriction; Vasoconstrictor Agents; Vasodilation; Vasodilator Agents | 2008 |
Attenuation of gastric mucosal inflammation induced by indomethacin through activation of the A2A adenosine receptor in rats.
Topics: Adenosine A2 Receptor Agonists; Adenosine A2 Receptor Antagonists; Animals; Anti-Inflammatory Agents, Non-Steroidal; Chemokine CXCL1; Dinoprostone; Gastric Mucosa; Indomethacin; Inflammation; Interleukin-1beta; Male; Peroxidase; Piperidines; Rats; Rats, Sprague-Dawley; Receptor, Adenosine A2A; Stomach Ulcer; Triazines; Triazoles; Tumor Necrosis Factor-alpha | 2009 |
Analysis of amorphous solid dispersions using 2D solid-state NMR and (1)H T(1) relaxation measurements.
Topics: Acetaminophen; Chemistry, Pharmaceutical; Crystallization; Dextrans; Dosage Forms; Indomethacin; Ketolides; Magnetic Resonance Spectroscopy; Pyrimidines; Solubility; Suspensions; Trehalose; Triazoles; Voriconazole | 2010 |
Thiazolo[3,2-b]-1,2,4-triazole-5(6H)-one substituted with ibuprofen: novel non-steroidal anti-inflammatory agents with favorable gastrointestinal tolerance.
Topics: Analgesics; Animals; Anti-Inflammatory Agents, Non-Steroidal; Carrageenan; Dose-Response Relationship, Drug; Drug Tolerance; Edema; Female; Ibuprofen; Indomethacin; Male; Mice; Pain Measurement; Stomach; Stomach Ulcer; Structure-Activity Relationship; Triazoles | 2012 |
Synthesis and evaluation of anti-inflammatory and analgesic activities of new 1,2,4-triazole derivatives.
Topics: Analgesics; Animals; Anti-Inflammatory Agents; Carrageenan; Edema; Hindlimb; Indomethacin; Injections, Intraperitoneal; Male; Mice; Morphine; Pain; Rats; Rats, Wistar; Triazoles | 2014 |
Sex differences in the role of NADPH oxidases in endothelium-dependent vasorelaxation in porcine isolated coronary arteries.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Animals; Benzoxazoles; Bradykinin; Coronary Vessels; Endothelium, Vascular; Female; Indomethacin; Male; NADPH Oxidases; NG-Nitroarginine Methyl Ester; Oxidation-Reduction; Sex Characteristics; Swine; Triazoles; Vasodilation | 2015 |
Guanosine may increase absence epileptic activity by means of A2A adenosine receptors in Wistar Albino Glaxo Rijswijk rats.
Topics: Adenosine A2 Receptor Antagonists; Animals; Anticonvulsants; Cyclooxygenase Inhibitors; Disease Models, Animal; Dose-Response Relationship, Drug; Electroencephalography; Epilepsy, Absence; Fourier Analysis; Guanosine; Indomethacin; Lipopolysaccharides; Purinergic P1 Receptor Antagonists; Pyrimidines; Rats; Rats, Wistar; Receptor, Adenosine A2A; Theophylline; Time Factors; Triazoles | 2016 |
Evaluation of Pharmacokinetic Interactions Between Lesinurad, a New Selective Urate Reabsorption Inhibitor, and Commonly Used Drugs for Gout Treatment.
Topics: Adult; Aged; Aged, 80 and over; Colchicine; Drug Administration Schedule; Drug Interactions; Female; Gout Suppressants; Humans; Hyperuricemia; Indomethacin; Male; Middle Aged; Naproxen; Thioglycolates; Treatment Outcome; Triazoles; Uricosuric Agents; Young Adult | 2017 |