triazoles has been researched along with ici 195739 in 48 studies
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 5 (10.42) | 18.7374 |
1990's | 37 (77.08) | 18.2507 |
2000's | 6 (12.50) | 29.6817 |
2010's | 0 (0.00) | 24.3611 |
2020's | 0 (0.00) | 2.80 |
Authors | Studies |
---|---|
Aguirre, T; Lazardi, K; Piras, MM; Piras, R; Urbina, JA | 1 |
de Souza, W; Lazardi, K; Urbina, JA | 1 |
Ryley, JF; Ryley, NG | 1 |
McCormack, JG; Seow, WK; Thong, YH; Vuddhakul, V | 1 |
Brummer, E; Hanson, LH; Stevens, DA; Tucker, RM | 1 |
Barrett-Bee, K; Campbell, J; Lees, J; Newboult, L; Pinder, P | 1 |
Boyle, FT; Gilman, DJ; Gravestock, MB; Wardleworth, JM | 1 |
McGregor, S; Ryley, JF; Wilson, RG | 1 |
Denning, DW; Hall, L; Hollis, S; Jackson, M | 1 |
Coffmann, S; Messer, SA; Pfaller, MA | 1 |
Anaissie, EJ; Dignani, MC; Hachem, R; Karyotakis, NC | 1 |
Denning, DW; Law, D; Mason, C; Moore, CB; Wardle, HM | 1 |
Graybill, JR; Holmberg, JD; Luther, MF; Najvar, LK | 1 |
Clemons, KV; Stevens, DA | 2 |
Bale, MJ; Buschelman, B; Pfaller, MA; Rhomberg, P | 1 |
Barchiesi, F; Colombo, AL; Fothergill, AW; McGough, DA; Rinaldi, MG | 1 |
Atkinson, BA; Bocanegra, R; Colombo, AL; Graybill, JR | 1 |
Denning, DW; Law, D; Moore, CB | 1 |
Galgiani, JN; Peng, T | 1 |
Mochizuki, H; Murakami, K; Ohashi, M; Tsuda, T; Watanabe, T; Yamada, H | 1 |
Maldonado, RA; Molina, J; Payares, G; Urbina, JA | 1 |
Clemons, KV; Hanson, LH; Stevens, DA | 1 |
Lazardi, K; Liendo, A; Molina, J; Payares, G; Perez, N; Piras, MM; Piras, R; Ryley, JF; Sanoja, C; Urbina, JA; Wincker, P | 1 |
Denning, DW; Kelly, SL; Manning, NJ; Venkateswarlu, K | 1 |
Kierszenbaum, F | 1 |
Dagger, F; Hernandez, A; Liendo, A; Rangel, H; Urbina, JA | 1 |
Cartledge, JD; Clumeck, N; De Wit, S; Denning, DW; Dupont, B; Gazzard, BG; Hawkins, DA | 1 |
Hollis, RJ; Pfaller, MA; Zhang, J | 1 |
Cutright, JL; Fidel, PL; Sobel, JD | 1 |
Denning, DW; Kelly, SL; Venkateswarlu, K | 1 |
Urbina, JA | 2 |
Kato, K; Mochizuki, H; Watanabe, T; Yamada, H | 1 |
Cartledge, JD; Clumeck, N; De Wit, S; Denning, DW; Dupont, B; Gazzard, BG; Hawkins, DA; Midgley, J | 1 |
Lazardi, K; Liendo, A; Urbina, JA | 1 |
Clumeck, AN; De Wit, S; Edwards, J; O'Doherty, E; Smith, RP; Yates, R | 1 |
Hitchcock, CA; Koltin, Y | 1 |
Aoki, FH; Branchini, ML; Mikami, Y; Miyaji, M; Nishimura, K; Taguchi, H; Yamamoto, K; Yang, HC; Yazawa, K | 1 |
Atkinson, G; Denning, DW; Hollis, S; Hood, SV; Percy, M; Williams, K | 1 |
Back, DJ; Evans, JA; McCormick, AD; McKillop, D; Tjia, J | 1 |
Aldridge, A; Duffy, PA; Harada, T; Inokuma, M; Matsunaga, T; Mitsui, T; Shibutani, Y | 1 |
Kikuchi, M; Kojima, M; Mikami, Y; Mochizuki, H; Nakamura, S; Nakanishii, T; Takahashi, Y; Yamada, H | 1 |
Aldridge, A; Duffy, PA; Harada, T; Matsunaga, T; Mitsui, T; Murano, H; Shibutani, Y | 1 |
Harada, T; Hirata, Z; Matsunaga, T; Mitsui, T; Murano, H; Shibutani, Y | 1 |
Brener, Z; Molina, J; Romanha, AJ; Urbina, JA | 1 |
Brener, Z; Gref, R; Molina, J; Urbina, J | 1 |
Denning, DW; Williams, KJ | 1 |
4 review(s) available for triazoles and ici 195739
Article | Year |
---|---|
Can a killer be arrested?
Topics: Animals; Chagas Disease; Humans; Insect Vectors; Mice; Triazoles; Trypanocidal Agents; Trypanosoma cruzi | 1996 |
Lipid biosynthesis pathways as chemotherapeutic targets in kinetoplastid parasites.
Topics: Animals; Antiprotozoal Agents; Cytochrome P-450 Enzyme Inhibitors; Drug Design; Kinetoplastida; Lipids; Methyltransferases; Oxidoreductases; Parasites; Phospholipids; Sterol 14-Demethylase; Sterols; Triazoles | 1997 |
The search for new triazole antifungal agents.
Topics: Antifungal Agents; Drugs, Investigational; Humans; Pyrimidines; Triazoles; Voriconazole | 1997 |
Specific treatment of Chagas disease: current status and new developments.
Topics: Chagas Disease; Cysteine Proteinase Inhibitors; Humans; Quinazolines; Triazoles | 2001 |
4 trial(s) available for triazoles and ici 195739
Article | Year |
---|---|
A dose comparison study of a new triazole antifungal (D0870) in HIV-positive patients with oral candidiasis.
Topics: Adolescent; Adult; AIDS-Related Opportunistic Infections; Antifungal Agents; Candida; Candida albicans; Candidiasis; Double-Blind Method; Female; Follow-Up Studies; Humans; Male; Microbial Sensitivity Tests; Middle Aged; Mouth Diseases; Recurrence; Treatment Outcome; Triazoles | 1997 |
Treatment of HIV-related fluconazole-resistant oral candidosis with D0870, a new triazole antifungal.
Topics: AIDS-Related Opportunistic Infections; Antifungal Agents; Candida; Candida albicans; Candidiasis, Oral; Drug Resistance, Microbial; Fluconazole; Humans; Male; Microbial Sensitivity Tests; Pilot Projects; Treatment Outcome; Triazoles | 1998 |
Pharmacokinetics of two multiple-dosing regimens of D0870 in human immunodeficiency virus-positive patients: a phase I study.
Topics: Adolescent; Adult; Antifungal Agents; Area Under Curve; Half-Life; HIV Seropositivity; Humans; Male; Middle Aged; Triazoles | 1998 |
Assessment of therapeutic response of oropharyngeal and esophageal candidiasis in AIDS with use of a new clinical scoring system: studies with D0870.
Topics: AIDS-Related Opportunistic Infections; Antifungal Agents; Candida albicans; Candidiasis, Oral; Colony Count, Microbial; Drug Resistance, Microbial; Esophageal Diseases; Fluconazole; Humans; Microbial Sensitivity Tests; Prospective Studies; Treatment Outcome; Triazoles | 1999 |
40 other study(ies) available for triazoles and ici 195739
Article | Year |
---|---|
Antiproliferative effects and mechanism of action of ICI 195,739, a novel bis-triazole derivative, on epimastigotes and amastigotes of Trypanosoma (Schizotrypanum) cruzi.
Topics: Animals; Cell Division; Chromatography, Gas; Chromatography, Thin Layer; Ergosterol; Naphthalenes; Terbinafine; Triazoles; Trypanocidal Agents; Trypanosoma cruzi; Vero Cells | 1991 |
Ultrastructural alterations induced by ICI 195,739, a bis-triazole derivative with strong antiproliferative action against Trypanosoma (Schizotrypanum) cruzi.
Topics: Animals; Ergosterol; Ketoconazole; Naphthalenes; Terbinafine; Triazoles; Trypanocidal Agents; Trypanosoma cruzi; Vero Cells | 1991 |
Candida albicans--do mycelia matter?
Topics: Amphotericin B; Animals; Candida albicans; Candidiasis; Culture Media; Kidney Cortex; Kidney Diseases; Kidney Glomerulus; Mice; Triazoles | 1990 |
Effects of the newer antifungal agents (bifonazole, ICI 195, 739 and amorolfin) on in vitro phagocytic, lymphocytic and natural-killer cell responses.
Topics: Antifungal Agents; Humans; Imidazoles; In Vitro Techniques; Killer Cells, Natural; Lymphocyte Activation; Lymphocytes; Morpholines; Neutrophils; Phagocytosis; Triazoles | 1989 |
Activity of ICI 195,739, a new oral triazole, compared with that of ketoconazole in the therapy of experimental murine blastomycosis.
Topics: Animals; Antifungal Agents; Blastomyces; Blastomycosis; Ketoconazole; Male; Mice; Mice, Inbred BALB C; Time Factors; Triazoles | 1989 |
Biochemical studies with a novel antifungal agent, ICI 195,739.
Topics: Animals; Antifungal Agents; Aromatase; Candida albicans; Cytochrome P-450 Enzyme System; Female; Humans; Kinetics; Lanosterol; Male; Placenta; Pregnancy; Rats; Steroids; Sterols; Testosterone; Triazoles | 1988 |
Synthesis and structure-activity relationships of a novel antifungal agent, ICI 195,739.
Topics: Animals; Antifungal Agents; Candida albicans; Candidiasis, Vulvovaginal; Female; Mice; Microbial Sensitivity Tests; Molecular Structure; Structure-Activity Relationship; Triazoles | 1988 |
Activity of ICI 195,739--a novel, orally active bistriazole--in rodent models of fungal and protozoal infections.
Topics: Animals; Antifungal Agents; Antiprotozoal Agents; Candidiasis, Vulvovaginal; Disease Models, Animal; Drug Evaluation, Preclinical; Female; Malaria; Mice; Rats; Structure-Activity Relationship; Tinea; Triazoles; Trypanosomiasis | 1988 |
Efficacy of D0870 compared with those of itraconazole and amphotericin B in two murine models of invasive aspergillosis.
Topics: Amphotericin B; Animals; Antifungal Agents; Aspergillosis; Aspergillus fumigatus; Colony Count, Microbial; Female; Immunosuppression Therapy; Itraconazole; Leukocyte Count; Lung Diseases, Fungal; Mice; Mice, Inbred Strains; Microbial Sensitivity Tests; Neutrophils; Triazoles | 1995 |
Comparison of visual and spectrophotometric methods of MIC endpoint determinations by using broth microdilution methods to test five antifungal agents, including the new triazole D0870.
Topics: Antifungal Agents; Candida; Candida albicans; Evaluation Studies as Topic; Humans; Microbial Sensitivity Tests; Reference Standards; Spectrophotometry; Triazoles | 1995 |
Activities of D0870, a novel triazole, against Candida lusitaniae and Trichosporon beigelii in experimental murine infections.
Topics: Animals; Antifungal Agents; Candida; Candidiasis; Male; Mice; Microbial Sensitivity Tests; Mycoses; Triazoles; Trichosporon | 1995 |
In vitro activity of D0870 compared with those of other azoles against fluconazole-resistant Candida spp.
Topics: Antifungal Agents; Candida; Drug Resistance, Microbial; Fluconazole; Itraconazole; Ketoconazole; Microbial Sensitivity Tests; Triazoles | 1995 |
Fluconazole, D0870, and flucytosine treatment of disseminated Candida tropicalis infections in mice.
Topics: Animals; Antifungal Agents; Candidiasis; Drug Therapy, Combination; Fluconazole; Flucytosine; Mice; Mice, Inbred ICR; Triazoles | 1995 |
Efficacy of the triazole D0870 in a murine model of systemic histoplasmosis.
Topics: Animals; Antifungal Agents; Female; Fluconazole; Histoplasmosis; Liver; Mice; Spleen; Triazoles | 1995 |
Antifungal activity of a new triazole, D0870, compared with four other antifungal agents tested against clinical isolates of Candida and Torulopsis glabrata.
Topics: Antifungal Agents; Candida; Fluconazole; Itraconazole; Microbial Sensitivity Tests; Triazoles | 1994 |
In vitro activity of a new antifungal triazole, D0870, against Candida albicans isolates from oral cavities of patients infected with human immunodeficiency virus.
Topics: AIDS-Related Opportunistic Infections; Antifungal Agents; Candida albicans; Candidiasis, Oral; Drug Resistance, Microbial; Humans; Microbial Sensitivity Tests; Stereoisomerism; Triazoles | 1994 |
Treatment of disseminated Torulopsis glabrata infection with DO870 and amphotericin B.
Topics: Amphotericin B; Animals; Antifungal Agents; Candidiasis; Drug Synergism; Drug Therapy, Combination; Fluconazole; Immunosuppression Therapy; Kidney; Male; Mice; Mice, Inbred ICR; Microbial Sensitivity Tests; Spleen; Triazoles | 1994 |
Utility of the triazole D0870 in the treatment of experimental systemic coccidioidomycosis.
Topics: Animals; Antifungal Agents; Coccidioides; Coccidioidomycosis; Dose-Response Relationship, Drug; Drug Administration Schedule; Female; Fluconazole; Liver; Lung; Mice; Mice, Inbred Strains; Spleen; Stereoisomerism; Triazoles | 1994 |
In-vitro activity of the new triazole D0870 compared with amphotericin B and itraconazole against Aspergillus spp.
Topics: Amphotericin B; Antifungal Agents; Aspergillus; Aspergillus flavus; Aspergillus fumigatus; Aspergillus niger; Itraconazole; Microbial Sensitivity Tests; Reproducibility of Results; Stereoisomerism; Triazoles | 1993 |
In vitro studies of a new antifungal triazole, D0870, against Candida albicans, Cryptococcus neoformans, and other pathogenic yeasts.
Topics: Antifungal Agents; Candida albicans; Cryptococcus neoformans; Hydrogen-Ion Concentration; Microbial Sensitivity Tests; Temperature; Triazoles | 1993 |
In vitro and in vivo antifungal activities of D0870, a new triazole agent.
Topics: Animals; Antifungal Agents; Culture Media; Fungi; Hydrogen-Ion Concentration; Immunosuppression Therapy; Male; Mice; Mice, Inbred ICR; Microbial Sensitivity Tests; Mycoses; Stereoisomerism; Triazoles | 1993 |
Experimental chemotherapy with combinations of ergosterol biosynthesis inhibitors in murine models of Chagas' disease.
Topics: Animals; Antifungal Agents; Chagas Disease; Disease Models, Animal; Ergosterol; Female; Ketoconazole; Mice; Naphthalenes; Terbinafine; Triazoles; Trypanocidal Agents | 1993 |
Activities of the triazole D0870 in vitro and against murine blastomycosis.
Topics: Animals; Antifungal Agents; Blastomyces; Blastomycosis; Fluconazole; Male; Mice; Microbial Sensitivity Tests; Triazoles | 1993 |
Cure of short- and long-term experimental Chagas' disease using D0870.
Topics: Animals; Base Sequence; Chagas Disease; Drug Administration Schedule; Ketoconazole; Molecular Sequence Data; Nifurtimox; Sterols; Time Factors; Triazoles; Trypanocidal Agents; Trypanosoma cruzi | 1996 |
Comparison of D0870, a new triazole antifungal agent, to fluconazole for inhibition of Candida albicans cytochrome P-450 by using in vitro assays.
Topics: Antifungal Agents; Candida albicans; Cytochrome P-450 Enzyme System; Ergosterol; Fluconazole; Gas Chromatography-Mass Spectrometry; Humans; Microbial Sensitivity Tests; Microsomes; Structure-Activity Relationship; Triazoles | 1996 |
Naturally azole-resistant Leishmania braziliensis promastigotes are rendered susceptible in the presence of terbinafine: comparative study with azole-susceptible Leishmania mexicana promastigotes.
Topics: Animals; Antifungal Agents; Azoles; Cytochrome P-450 Enzyme Inhibitors; Drug Interactions; Drug Resistance; Enzyme Inhibitors; Ketoconazole; Leishmania braziliensis; Leishmania mexicana; Naphthalenes; Oxidoreductases; Squalene; Sterol 14-Demethylase; Sterols; Terbinafine; Triazoles | 1996 |
Variations in DNA subtype and antifungal susceptibility among clinical isolates of Candida tropicalis.
Topics: Amphotericin B; Antifungal Agents; Candida; Candidiasis; Cross Infection; DNA, Fungal; Electrophoresis, Gel, Pulsed-Field; Fluconazole; Flucytosine; Humans; Itraconazole; Microbial Sensitivity Tests; Mycological Typing Techniques; Polymorphism, Restriction Fragment Length; Triazoles | 1997 |
Efficacy of D0870 treatment of experimental Candida vaginitis.
Topics: Animals; Antifungal Agents; Candidiasis; Drug Resistance, Microbial; Female; Fluconazole; Mice; Mice, Inbred CBA; Microbial Sensitivity Tests; Triazoles; Vaginitis | 1997 |
In-vitro activity of D0870, a new triazole antifungal drug, in comparison with fluconazole and itraconazole against Aspergillus fumigatus and Candida krusei.
Topics: Antifungal Agents; Aspergillus fumigatus; Candida; Carbon Monoxide; Cytochrome P-450 Enzyme System; Dose-Response Relationship, Drug; Ergosterol; Fluconazole; Itraconazole; Time Factors; Triazoles | 1997 |
Fungicidal mechanism of action of D0870 against Cryptococcus neoformans under acidic conditions.
Topics: Antifungal Agents; Cryptococcus neoformans; Hydrogen-Ion Concentration; Microbial Sensitivity Tests; Potassium; Sterols; Triazoles | 1997 |
In-vitro antiproliferative effects and mechanism of action of the bis-triazole D0870 and its S(-) enantiomer against Trypanosoma cruzi.
Topics: Animals; Cell Division; Chlorocebus aethiops; Dose-Response Relationship, Drug; Sterols; Triazoles; Trypanocidal Agents; Trypanosoma cruzi; Vero Cells | 1998 |
Colorimetric MTT assessment of antifungal activity of D0870 against fluconazole-resistant Candida albicans.
Topics: Antifungal Agents; Candida albicans; Candidiasis; Colorimetry; Drug Resistance, Microbial; Fluconazole; Humans; Microbial Sensitivity Tests; Tetrazolium Salts; Thiazoles; Triazoles | 1998 |
Preclinical and in vitro assessment of the potential of D0870, an antifungal agent, for producing clinical drug interactions.
Topics: Animals; Antifungal Agents; Chromatography, High Pressure Liquid; Cytochrome P-450 Enzyme System; Drug Interactions; Female; Humans; Hypnotics and Sedatives; Inhibitory Concentration 50; Kinetics; Male; Microsomes, Liver; Models, Chemical; Pentobarbital; Rats; Time Factors; Triazoles | 1999 |
QT prolongation and torsades de pointes induced by an antifungal agent, D0870, in conscious dogs.
Topics: Animals; Antifungal Agents; Dogs; Electrocardiography; Female; Male; Torsades de Pointes; Triazoles | 1999 |
Antifungal activities of D0870 against fluconazole-resistant Candida albicans.
Topics: Animals; Antifungal Agents; Candida albicans; Drug Resistance, Microbial; Fluconazole; Male; Mice; Mice, Inbred ICR; Triazoles | 1999 |
Influences of catecholamines on the sudden death induced in dogs by an antifungal agent, D0870.
Topics: Action Potentials; Animals; Antifungal Agents; Catecholamines; Death, Sudden, Cardiac; Dogs; Electrocardiography; Epinephrine; Heart Ventricles; Isoproterenol; Torsades de Pointes; Triazoles | 2000 |
D0870, an antifungal agent, induces reverse use-dependent QT prolongation in dogs.
Topics: Action Potentials; Animals; Antifungal Agents; Dogs; Electric Stimulation; Electrocardiography, Ambulatory; Female; Male; Purkinje Fibers; Torsades de Pointes; Triazoles | 2000 |
In vivo activity of the bis-triazole D0870 against drug-susceptible and drug-resistant strains of the protozoan parasite Trypanosoma cruzi.
Topics: Animals; Chagas Disease; Drug Resistance; Female; Mice; Triazoles; Trypanocidal Agents; Trypanosoma cruzi | 2000 |
Cure of experimental Chagas' disease by the bis-triazole DO870 incorporated into 'stealth' polyethyleneglycol-polylactide nanospheres.
Topics: Animals; Chagas Disease; Disease Models, Animal; Drug Carriers; Drug Delivery Systems; Female; Mice; Microspheres; Polyesters; Polyethylene Glycols; Treatment Outcome; Triazoles; Trypanocidal Agents; Trypanosoma cruzi | 2001 |
Termination of development of D0870.
Topics: Animals; Antifungal Agents; Drug Design; Drug Industry; Humans; Long QT Syndrome; Triazoles | 2001 |