Page last updated: 2024-08-24

triazoles and heme

triazoles has been researched along with heme in 35 studies

Research

Studies (35)

TimeframeStudies, this research(%)All Research%
pre-199023 (65.71)18.7374
1990's3 (8.57)18.2507
2000's1 (2.86)29.6817
2010's6 (17.14)24.3611
2020's2 (5.71)2.80

Authors

AuthorsStudies
Bhat, KS; Padmanaban, G; Sardana, MK1
Kappas, A; Maines, MD1
Jones, GL; Masters, CJ1
Mackie, JE; Marks, GS; Massey, TE; Riddick, DS1
Muller-Eberhard, U; Ross, JD1
Beattie, DS1
Baron, J; Tephly, TR2
Feinstein, RN; Howard, JB; Jaroslow, BN1
Castro, JA; D'Acosta, N; de Castro, CR; de Fenos, OM; de Ferreyra, EC; Díaz Gòmez, MI1
Woods, JS1
Nichol, AW1
Chang, JY; Schroeder, WA1
Mohr, P; Müller, K; Pfeil, W; Rein, H; Ristau, O; Scheler, W1
Imai, Y; Siekevitz, P1
Baron, J; Hasegawa, E; Tephly, TR1
Gallasch, J; Garleb, C; Mohr, P; Scheler, W1
Fränk, K; Mohr, P; Scheler, W2
Israels, LG; Levitt, M; Schacter, BA; Zipursky, A1
Mohr, P; Müller, K; Scheler, W; Schumann, H1
Kumar, CC; Padmanaban, G1
Padmanaban, G; Ravishankar, H1
Mathews, JM; Ortiz de Montellano, PR1
Bend, JR; Halpert, JR; Hanna, IH; Hollenberg, PF; Kent, UM; Szklarz, GD; Vaz, AD1
Di Re, J; Lee, C; Riddick, DS1
Hutzler, JM; Locuson, CW; Tracy, TS1
Chiesa, M; Di Nardo, G; Ferrero, VE; Giamello, E; Gilardi, G; Maurelli, S; Van Doorslaer, S1
Isoherranen, N; Kunze, KL; Liu, JO; Lutz, JD; Nelson, WL; Peng, CC; Shi, W1
Atkins, WM; Bowman, MK; Conner, KP; Krzyaniak, MD; Vennam, P; Woods, CM1
Akinfieva, OV; Artem'eva, MM; Daliger, IL; Medvedev, OS; Medvedeva, NA; Postnikov, AB; Shevelev, SA1
Bratus', LV; Frantsuzova, SB; Havenauskas, BL; Honchar, OO; Man'kovs'ka, IM; Nosar, VI; Opanasenko, HB1
Divsalar, A; Ghalandari, B; Harifi, AR; Moradi, M; Saboury, AA1
Chen, P; Li, Y; Lu, L; Wang, H; Wei, X; Zhang, C; Zhang, Y1
Ascenção, K; Coukos, G; Dilek, N; Irving, M; Majjigapu, SR; Michielin, O; Pojer, F; Reichenbach, P; Reynaud, A; Röhrig, UF; Vogel, P; Zoete, V1

Other Studies

35 other study(ies) available for triazoles and heme

ArticleYear
Role of haem in the synthesis and assembly of cytochrome P-450.
    The Biochemical journal, 1977, May-15, Volume: 164, Issue:2

    Topics: Aminolevulinic Acid; Animals; Apoenzymes; Binding Sites; Cytochrome P-450 Enzyme System; Heme; Hemin; Male; Microsomes, Liver; Phenobarbital; Rats; Triazoles

1977
Cobalt stimulation of heme degradation in the liver. Dissociation of microsomal oxidation of heme from cytochrome P-450.
    The Journal of biological chemistry, 1975, Jun-10, Volume: 250, Issue:11

    Topics: 5-Aminolevulinate Synthetase; Allylisopropylacetamide; Animals; Bilirubin; Cobalt; Cytochrome P-450 Enzyme System; Cytochrome Reductases; Dactinomycin; Ethylmorphine-N-Demethylase; Heme; Iodides; Liver; Microsomes, Liver; Oxygen Consumption; Porphyrins; Puromycin; Rats; Thiocyanates; Time Factors; Triazoles; Urea

1975
On the nature and characteristics of the multiple forms of catalase in mouse liver.
    Archives of biochemistry and biophysics, 1975, Volume: 169, Issue:1

    Topics: Animals; Carbon Radioisotopes; Catalase; Chromatography, Gel; Cytosine Nucleotides; Electrophoresis, Polyacrylamide Gel; Electrophoresis, Starch Gel; Female; Heme; Iron; Iron Radioisotopes; Isoelectric Focusing; Isoelectric Point; Liver; Methods; Mice; Neuraminidase; Sialic Acids; Spectrum Analysis; Triazoles; Ultracentrifugation

1975
3,5-Diethoxycarbonyl-2,6-dimethyl-4-ethyl-1,4-dihydropyridine inactivates rat liver cytochrome P-450c, but not its orthologue, rabbit lung form 6.
    Canadian journal of physiology and pharmacology, 1990, Volume: 68, Issue:3

    Topics: Animals; Benzoflavones; beta-Naphthoflavone; Cytochrome P-450 Enzyme Inhibitors; Dicarbethoxydihydrocollidine; Dihydropyridines; Heme; In Vitro Techniques; Isoenzymes; Liver; Lung; Male; Microsomes; Rabbits; Rats; Species Specificity; Triazoles

1990
In vivo effect of inhibitors of heme biosynthesis on serum hemopexin (Hx) levels and its pharmacological induction.
    Biochemical and biophysical research communications, 1970, Dec-24, Volume: 41, Issue:6

    Topics: Acetates; Animals; Benzopyrenes; Beta-Globulins; Enzyme Induction; Heme; Lead; Male; Microsomes, Liver; Protein Binding; Protein Biosynthesis; Pyridines; Rabbits; Triazoles

1970
The possible relationship between heme synthesis and mitochondrial biogenesis.
    Archives of biochemistry and biophysics, 1971, Volume: 147, Issue:1

    Topics: Acetamides; Acyltransferases; Allyl Compounds; Animals; Carbon Isotopes; Cytochromes; Electron Transport Complex IV; Enzyme Induction; Glycine; Heme; Leucine; Levulinic Acids; Male; Mitochondria, Liver; Rats; Stimulation, Chemical; Succinates; Triazoles; Tritium

1971
The role of heme synthesis during the induction of hepatic microsomal cytochrome P-450 and drug metabolism produced by benzpyrene.
    Biochemical and biophysical research communications, 1969, Aug-15, Volume: 36, Issue:4

    Topics: Acyltransferases; Amino Acids; Animals; Azo Compounds; Benzopyrenes; Carbon Isotopes; Cytochromes; Depression, Chemical; Enzyme Induction; Glycine; Heme; Levulinic Acids; Liver; Male; Microsomes; NADP; Oxidoreductases; Phenobarbital; Rats; Stimulation, Chemical; Time Factors; Transferases; Triazoles

1969
Effect of 3-amino-1,2,4-triazole on the stimulation of hepatic microsomal heme synthesis and induction of hepatic microsomal oxidases produced by phenobarbital.
    Molecular pharmacology, 1969, Volume: 5, Issue:1

    Topics: Animals; Azo Compounds; Carbon Isotopes; Cytochromes; Enzyme Induction; Heme; Hydro-Lyases; Iron Isotopes; Levulinic Acids; Male; Microsomes, Liver; Morphinans; NADP; Oxidoreductases; Phenobarbital; Rats; Time Factors; Triazoles

1969
Molecular location of the genetic lesion in the acatalasemic mouse.
    Biochemical genetics, 1972, Volume: 6, Issue:4

    Topics: Animals; Azides; Catalase; Chromatography, Ion Exchange; Drug Stability; Goats; Guanidines; Heme; Hydroxylamines; Immune Sera; Liver; Mice; Mutation; Protein Conformation; Protein Denaturation; Rabbits; Triazoles; Trypsin; Urea

1972
Role of cytochrome P-450 in carbon tetrachloride activation and CCl 4-induced necrosis. Effect of inhibitors of heme synthesis. I. 3-Amino-1,2,4 triazole.
    Research communications in chemical pathology and pharmacology, 1973, Volume: 6, Issue:1

    Topics: Animals; Carbon Isotopes; Carbon Tetrachloride; Carbon Tetrachloride Poisoning; Cytochrome P-450 Enzyme System; Drug Interactions; Enzyme Activation; Female; Heme; Lipid Metabolism; Liver; Male; Microsomes, Liver; Necrosis; Organ Size; Phenobarbital; Triazoles

1973
Studies on the role of heme in the regulation of delta-aminolevulinic acid synthetase during fetal hepatic development.
    Molecular pharmacology, 1974, Volume: 10, Issue:3

    Topics: 5-Aminolevulinate Synthetase; Animals; Cycloheximide; Endoplasmic Reticulum; Fetus; Heme; Liver; Microsomes, Liver; Protein Biosynthesis; Rats; Rats, Inbred Strains; Time Factors; Triazoles

1974
The formation of biliverdin by chicken macrophages in tissue culture. Observations on the effect of inhibitors.
    Biochimica et biophysica acta, 1970, Oct-27, Volume: 222, Issue:1

    Topics: Acetanilides; Animals; Ascorbic Acid; Azides; Bile Pigments; Carbon Monoxide; Chickens; Chloramphenicol; Culture Techniques; Cyanides; Cycloheximide; Dactinomycin; Erythrocytes; Ethylmaleimide; Female; Heme; Hydrogen Peroxide; Macrophages; Metabolism; Microscopy, Phase-Contrast; Mitomycins; Phagocytosis; Phenobarbital; Proadifen; Quinacrine; Spectrophotometry; Spectrum Analysis; Stimulation, Chemical; Triazoles

1970
Reaction of 3-amino-1:2:4-triazole with bovine liver catalase and human erythrocyte catalase.
    Archives of biochemistry and biophysics, 1972, Volume: 148, Issue:2

    Topics: Adenosine Monophosphate; Amines; Amino Acids; Animals; Catalase; Cattle; Chemical Phenomena; Chemistry; Erythrocytes; Heme; Histidine; Humans; Hydrogen Peroxide; Liver; Methods; Protein Binding; Rats; Rats, Inbred Strains; Time Factors; Triazoles

1972
[Studies in the nature of ligand receptor relations in methemoglobin complexes with imidazols,1,2,4-triazol and pyridines].
    Acta biologica et medica Germanica, 1972, Volume: 28, Issue:2

    Topics: Animals; Binding Sites; Chromatography, Gel; Diptera; Fishes; Heme; Horses; Humans; Hydrogen-Ion Concentration; Imidazoles; In Vitro Techniques; Methemoglobin; Methods; Protein Binding; Pyridines; Spectrophotometry; Triazoles

1972
A comparison of some properties of microsomal cytochrome P-450 from normal, methylcholanthrene-, and phenobarbital-treated rats.
    Archives of biochemistry and biophysics, 1971, Volume: 144, Issue:1

    Topics: 1-Propanol; Amines; Animals; Chemical Phenomena; Chemistry; Chlorides; Cycloheximide; Cytochromes; Fasting; Fatty Alcohols; Heme; Hydrogen-Ion Concentration; Kinetics; Male; Mathematics; Mercury; Methylcholanthrene; Microsomes, Liver; Nitriles; Oxidation-Reduction; Phenobarbital; Potassium; Protein Biosynthesis; Rats; Spectrophotometry; Sulfites; Thiocyanates; Triazoles

1971
Effect of drugs on heme synthesis in the liver.
    Metabolism: clinical and experimental, 1971, Volume: 20, Issue:2

    Topics: Acyltransferases; Animals; Benzopyrenes; Cytochromes; Depression, Chemical; Glycine; Heme; Lead; Levulinic Acids; Liver; Lyases; Microsomes, Liver; Mitochondria; Oxidoreductases; Phenobarbital; Pyridines; Rats; Stimulation, Chemical; Succinates; Triazoles

1971
[Spectrophotometric studies on the influence of pyridine derivatives on the NH acidity of heme-coordinated imidazole and 1,2,4-triazole].
    Acta biologica et medica Germanica, 1967, Volume: 18, Issue:5

    Topics: Chemical Phenomena; Chemistry; Heme; Imidazoles; Pyridines; Spectrophotometry; Triazoles

1967
[Spectrophotometric studies on the NH-acidity of hemin-diethylester-imidazoles and 1,2,4-triazole].
    Die Naturwissenschaften, 1967, Volume: 54, Issue:9

    Topics: Amines; Animals; Diptera; Heme; Hydrogen-Ion Concentration; Imidazoles; Methemoglobin; Spectrophotometry; Triazoles

1967
The nonerythropoietic component of early bilirubin.
    The Journal of clinical investigation, 1968, Volume: 47, Issue:6

    Topics: Amides; Amino Acids; Animals; Bile Ducts; Biliary Fistula; Bilirubin; Carbon Isotopes; Catalase; Cycloheximide; Cytochromes; Erythropoiesis; Glycine; Heme; Infusions, Parenteral; Kidney; Lead Poisoning; Levulinic Acids; Male; Nephrectomy; Phenobarbital; Porphyrins; Protein Biosynthesis; Rats; Triazoles

1968
[Spectral and chemical behavior of hemin diethylester and its complexes with imidazole and 1,2,4-triazole derivatives in anhydrous dimethylsulfoxide].
    Acta biologica et medica Germanica, 1968, Volume: 20, Issue:3

    Topics: Animals; Biochemical Phenomena; Biochemistry; Cattle; Dimethyl Sulfoxide; Esters; Ethanol; Heme; Hydrogen-Ion Concentration; Imidazoles; Mathematics; Spectrophotometry; Spectrum Analysis; Triazoles

1968
Ligand-protein interactions in imidazole and 1,2,4-triazole complexes of methaemoglobin from Chironomus plumosus.
    European journal of biochemistry, 1967, Volume: 3, Issue:2

    Topics: Animals; Chemical Phenomena; Chemistry, Physical; Chromatography, Gel; Freezing; Heme; Hydrogen-Ion Concentration; Imidazoles; Macromolecular Substances; Methemoglobin; Models, Chemical; Protein Binding; Receptors, Drug; Spectrophotometry; Triazoles

1967
3-Amino-1,2,4-triazole is an inhibitor of protein synthesis on mitoribosomes in Neurospora crassa.
    Biochimica et biophysica acta, 1980, Apr-30, Volume: 607, Issue:2

    Topics: Amitrole; Chloramphenicol; Fungal Proteins; Heme; Mitochondria; Neurospora; Neurospora crassa; Ribosomes; Triazoles

1980
Effect of cobalt chloride and 3-amino-1,2,4-triazole on the induction of cytochrome P-450 synthesis by phenobarbitone in rat liver.
    Archives of biochemistry and biophysics, 1983, Volume: 225, Issue:1

    Topics: Amitrole; Animals; Cobalt; Cytochrome P-450 Enzyme System; Enzyme Induction; Heme; In Vitro Techniques; Male; Microsomes, Liver; Phenobarbital; Protein Biosynthesis; Rats; Triazoles

1983
Autocatalytic alkylation of the cytochrome P-450 prosthetic haem group by 1-aminobenzotriazole. Isolation of an NN-bridged benzyne-protoporphyrin IX adduct.
    The Biochemical journal, 1981, Jun-01, Volume: 195, Issue:3

    Topics: Alkylation; Animals; Cytochrome P-450 Enzyme Inhibitors; Cytochromes; Cytochromes b5; Heme; In Vitro Techniques; Macromolecular Substances; Male; Microsomes, Liver; Protoporphyrins; Rats; Rats, Inbred Strains; Spectrophotometry; Triazoles

1981
Significance of glycine 478 in the metabolism of N-benzyl-1-aminobenzotriazole to reactive intermediates by cytochrome P450 2B1.
    Biochemistry, 1997, Sep-30, Volume: 36, Issue:39

    Topics: Animals; Binding Sites; Chromatography, High Pressure Liquid; Cytochrome P-450 CYP2B1; Glycine; Heme; Magnetic Resonance Spectroscopy; Male; Mass Spectrometry; Microsomes, Liver; Models, Chemical; Models, Molecular; Mutagenesis, Site-Directed; Rats; Rats, Inbred F344; Rats, Wistar; Triazoles

1997
Lack of mechanism-based inactivation of rat hepatic microsomal cytochromes P450 by doxorubicin.
    Canadian journal of physiology and pharmacology, 1999, Volume: 77, Issue:8

    Topics: Animals; Antibiotics, Antineoplastic; Carbon Tetrachloride; Cytochrome P-450 Enzyme System; Doxorubicin; Enzyme Activation; Heme; Lipid Peroxidation; Male; Microsomes, Liver; NADH, NADPH Oxidoreductases; Rats; Rats, Inbred F344; Triazoles

1999
Visible spectra of type II cytochrome P450-drug complexes: evidence that "incomplete" heme coordination is common.
    Drug metabolism and disposition: the biological fate of chemicals, 2007, Volume: 35, Issue:4

    Topics: Aniline Compounds; Aryl Hydrocarbon Hydroxylases; Benzodioxoles; Binding Sites; Cytochrome P-450 CYP2C9; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Enzyme Inhibitors; Fluconazole; Heme; Humans; Imidazoles; Itraconazole; Kinetics; Ligands; Light; Models, Chemical; Molecular Structure; NADP; Nonlinear Dynamics; Protein Binding; Pyrimidines; Recombinant Proteins; Reference Standards; Regression Analysis; Spectrum Analysis; Sulfaphenazole; Triazoles

2007
Direct spectroscopic evidence for binding of anastrozole to the iron heme of human aromatase. Peering into the mechanism of aromatase inhibition.
    Chemical communications (Cambridge, England), 2011, Oct-14, Volume: 47, Issue:38

    Topics: Anastrozole; Aromatase; Aromatase Inhibitors; Binding Sites; Computer Simulation; Electron Spin Resonance Spectroscopy; Heme; Humans; Iron; Nitriles; Quantum Theory; Triazoles

2011
Stereospecific metabolism of itraconazole by CYP3A4: dioxolane ring scission of azole antifungals.
    Drug metabolism and disposition: the biological fate of chemicals, 2012, Volume: 40, Issue:3

    Topics: Antifungal Agents; Azoles; Binding Sites; Catalytic Domain; Cytochrome P-450 CYP3A; Cytochrome P-450 CYP3A Inhibitors; Dioxolanes; Female; Heme; Humans; Hydroxylation; Iron; Itraconazole; Male; Metabolic Networks and Pathways; Midazolam; Stereoisomerism; Triazoles

2012
1,2,3-Triazole-heme interactions in cytochrome P450: functionally competent triazole-water-heme complexes.
    Biochemistry, 2012, Aug-14, Volume: 51, Issue:32

    Topics: Click Chemistry; Cytochrome P-450 CYP3A; Cytochrome P-450 CYP3A Inhibitors; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Electron Spin Resonance Spectroscopy; Ethinyl Estradiol; Heme; Imidazoles; Isomerism; Kinetics; Magnetic Resonance Spectroscopy; Protein Binding; Quantum Theory; Thermodynamics; Triazoles; Water

2012
[Peripheral mechanisms of action of oxatriazolium-5-olate derivative 3-(3-[1,2,4]-triazolo)oxatriazolium-5-olate in spontaneously hypertensive rats].
    Eksperimental'naia i klinicheskaia farmakologiia, 2012, Volume: 75, Issue:8

    Topics: Animals; Arteries; Guanylate Cyclase; Heme; Male; Nitric Oxide; Nitroprusside; Oxadiazoles; Phenylephrine; Quinoxalines; Rats; Rats, Inbred SHR; Rats, Wistar; Tail; Tissue Culture Techniques; Triazoles; Vasoconstrictor Agents; Vasodilation; Vasodilator Agents

2012
[Disturbances of oxygen-dependent processes in periodontal tissues under prolonged immobilization stress and ways of their pharmacological correction].
    Fiziolohichnyi zhurnal (Kiev, Ukraine : 1994), 2013, Volume: 59, Issue:1

    Topics: Adrenal Glands; Animals; Antioxidants; Cell Respiration; Flavin-Adenine Dinucleotide; Gingiva; Heme; Immobilization; Lipid Peroxidation; Male; Mitochondria; NAD; Organ Size; Oxidation-Reduction; Oxygen; Oxygen Consumption; Periodontium; Rats; Rats, Wistar; Stress, Physiological; Thymus Gland; Triazoles

2013
Inhibitory effects of deferasirox on the structure and function of bovine liver catalase: a spectroscopic and theoretical study.
    Journal of biomolecular structure & dynamics, 2015, Volume: 33, Issue:10

    Topics: Animals; Benzoates; Binding, Competitive; Catalase; Catalytic Domain; Cattle; Circular Dichroism; Deferasirox; Enzyme Inhibitors; Heme; Hydrophobic and Hydrophilic Interactions; Iron; Iron Chelating Agents; Kinetics; Liver; Molecular Docking Simulation; Protein Binding; Protein Structure, Secondary; Solutions; Spectrometry, Fluorescence; Temperature; Thermodynamics; Triazoles; Tryptophan

2015
Mitochondrial dysfunctions trigger the calcium signaling-dependent fungal multidrug resistance.
    Proceedings of the National Academy of Sciences of the United States of America, 2020, 01-21, Volume: 117, Issue:3

    Topics: Alkyl and Aryl Transferases; Antifungal Agents; Aspergillus fumigatus; Calcium Chelating Agents; Calcium Signaling; Chitin Synthase; Drug Resistance, Fungal; Fungal Proteins; Gene Expression Regulation, Fungal; Heme; Humans; Membrane Proteins; Mitochondria; Mitochondrial Diseases; Phosphoprotein Phosphatases; Reactive Oxygen Species; Transcription Factors; Triazoles

2020
Structure-based optimization of type III indoleamine 2,3-dioxygenase 1 (IDO1) inhibitors.
    Journal of enzyme inhibition and medicinal chemistry, 2022, Volume: 37, Issue:1

    Topics: Enzyme Inhibitors; Heme; Indoleamine-Pyrrole 2,3,-Dioxygenase; Triazoles

2022