triazoles has been researched along with heme in 35 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 23 (65.71) | 18.7374 |
| 1990's | 3 (8.57) | 18.2507 |
| 2000's | 1 (2.86) | 29.6817 |
| 2010's | 6 (17.14) | 24.3611 |
| 2020's | 2 (5.71) | 2.80 |
| Authors | Studies |
|---|---|
| Bhat, KS; Padmanaban, G; Sardana, MK | 1 |
| Kappas, A; Maines, MD | 1 |
| Jones, GL; Masters, CJ | 1 |
| Mackie, JE; Marks, GS; Massey, TE; Riddick, DS | 1 |
| Muller-Eberhard, U; Ross, JD | 1 |
| Beattie, DS | 1 |
| Baron, J; Tephly, TR | 2 |
| Feinstein, RN; Howard, JB; Jaroslow, BN | 1 |
| Castro, JA; D'Acosta, N; de Castro, CR; de Fenos, OM; de Ferreyra, EC; Díaz Gòmez, MI | 1 |
| Woods, JS | 1 |
| Nichol, AW | 1 |
| Chang, JY; Schroeder, WA | 1 |
| Mohr, P; Müller, K; Pfeil, W; Rein, H; Ristau, O; Scheler, W | 1 |
| Imai, Y; Siekevitz, P | 1 |
| Baron, J; Hasegawa, E; Tephly, TR | 1 |
| Gallasch, J; Garleb, C; Mohr, P; Scheler, W | 1 |
| Fränk, K; Mohr, P; Scheler, W | 2 |
| Israels, LG; Levitt, M; Schacter, BA; Zipursky, A | 1 |
| Mohr, P; Müller, K; Scheler, W; Schumann, H | 1 |
| Kumar, CC; Padmanaban, G | 1 |
| Padmanaban, G; Ravishankar, H | 1 |
| Mathews, JM; Ortiz de Montellano, PR | 1 |
| Bend, JR; Halpert, JR; Hanna, IH; Hollenberg, PF; Kent, UM; Szklarz, GD; Vaz, AD | 1 |
| Di Re, J; Lee, C; Riddick, DS | 1 |
| Hutzler, JM; Locuson, CW; Tracy, TS | 1 |
| Chiesa, M; Di Nardo, G; Ferrero, VE; Giamello, E; Gilardi, G; Maurelli, S; Van Doorslaer, S | 1 |
| Isoherranen, N; Kunze, KL; Liu, JO; Lutz, JD; Nelson, WL; Peng, CC; Shi, W | 1 |
| Atkins, WM; Bowman, MK; Conner, KP; Krzyaniak, MD; Vennam, P; Woods, CM | 1 |
| Akinfieva, OV; Artem'eva, MM; Daliger, IL; Medvedev, OS; Medvedeva, NA; Postnikov, AB; Shevelev, SA | 1 |
| Bratus', LV; Frantsuzova, SB; Havenauskas, BL; Honchar, OO; Man'kovs'ka, IM; Nosar, VI; Opanasenko, HB | 1 |
| Divsalar, A; Ghalandari, B; Harifi, AR; Moradi, M; Saboury, AA | 1 |
| Chen, P; Li, Y; Lu, L; Wang, H; Wei, X; Zhang, C; Zhang, Y | 1 |
| Ascenção, K; Coukos, G; Dilek, N; Irving, M; Majjigapu, SR; Michielin, O; Pojer, F; Reichenbach, P; Reynaud, A; Röhrig, UF; Vogel, P; Zoete, V | 1 |
35 other study(ies) available for triazoles and heme
| Article | Year |
|---|---|
Role of haem in the synthesis and assembly of cytochrome P-450.
Topics: Aminolevulinic Acid; Animals; Apoenzymes; Binding Sites; Cytochrome P-450 Enzyme System; Heme; Hemin; Male; Microsomes, Liver; Phenobarbital; Rats; Triazoles | 1977 |
Cobalt stimulation of heme degradation in the liver. Dissociation of microsomal oxidation of heme from cytochrome P-450.
Topics: 5-Aminolevulinate Synthetase; Allylisopropylacetamide; Animals; Bilirubin; Cobalt; Cytochrome P-450 Enzyme System; Cytochrome Reductases; Dactinomycin; Ethylmorphine-N-Demethylase; Heme; Iodides; Liver; Microsomes, Liver; Oxygen Consumption; Porphyrins; Puromycin; Rats; Thiocyanates; Time Factors; Triazoles; Urea | 1975 |
On the nature and characteristics of the multiple forms of catalase in mouse liver.
Topics: Animals; Carbon Radioisotopes; Catalase; Chromatography, Gel; Cytosine Nucleotides; Electrophoresis, Polyacrylamide Gel; Electrophoresis, Starch Gel; Female; Heme; Iron; Iron Radioisotopes; Isoelectric Focusing; Isoelectric Point; Liver; Methods; Mice; Neuraminidase; Sialic Acids; Spectrum Analysis; Triazoles; Ultracentrifugation | 1975 |
3,5-Diethoxycarbonyl-2,6-dimethyl-4-ethyl-1,4-dihydropyridine inactivates rat liver cytochrome P-450c, but not its orthologue, rabbit lung form 6.
Topics: Animals; Benzoflavones; beta-Naphthoflavone; Cytochrome P-450 Enzyme Inhibitors; Dicarbethoxydihydrocollidine; Dihydropyridines; Heme; In Vitro Techniques; Isoenzymes; Liver; Lung; Male; Microsomes; Rabbits; Rats; Species Specificity; Triazoles | 1990 |
In vivo effect of inhibitors of heme biosynthesis on serum hemopexin (Hx) levels and its pharmacological induction.
Topics: Acetates; Animals; Benzopyrenes; Beta-Globulins; Enzyme Induction; Heme; Lead; Male; Microsomes, Liver; Protein Binding; Protein Biosynthesis; Pyridines; Rabbits; Triazoles | 1970 |
The possible relationship between heme synthesis and mitochondrial biogenesis.
Topics: Acetamides; Acyltransferases; Allyl Compounds; Animals; Carbon Isotopes; Cytochromes; Electron Transport Complex IV; Enzyme Induction; Glycine; Heme; Leucine; Levulinic Acids; Male; Mitochondria, Liver; Rats; Stimulation, Chemical; Succinates; Triazoles; Tritium | 1971 |
The role of heme synthesis during the induction of hepatic microsomal cytochrome P-450 and drug metabolism produced by benzpyrene.
Topics: Acyltransferases; Amino Acids; Animals; Azo Compounds; Benzopyrenes; Carbon Isotopes; Cytochromes; Depression, Chemical; Enzyme Induction; Glycine; Heme; Levulinic Acids; Liver; Male; Microsomes; NADP; Oxidoreductases; Phenobarbital; Rats; Stimulation, Chemical; Time Factors; Transferases; Triazoles | 1969 |
Effect of 3-amino-1,2,4-triazole on the stimulation of hepatic microsomal heme synthesis and induction of hepatic microsomal oxidases produced by phenobarbital.
Topics: Animals; Azo Compounds; Carbon Isotopes; Cytochromes; Enzyme Induction; Heme; Hydro-Lyases; Iron Isotopes; Levulinic Acids; Male; Microsomes, Liver; Morphinans; NADP; Oxidoreductases; Phenobarbital; Rats; Time Factors; Triazoles | 1969 |
Molecular location of the genetic lesion in the acatalasemic mouse.
Topics: Animals; Azides; Catalase; Chromatography, Ion Exchange; Drug Stability; Goats; Guanidines; Heme; Hydroxylamines; Immune Sera; Liver; Mice; Mutation; Protein Conformation; Protein Denaturation; Rabbits; Triazoles; Trypsin; Urea | 1972 |
Role of cytochrome P-450 in carbon tetrachloride activation and CCl 4-induced necrosis. Effect of inhibitors of heme synthesis. I. 3-Amino-1,2,4 triazole.
Topics: Animals; Carbon Isotopes; Carbon Tetrachloride; Carbon Tetrachloride Poisoning; Cytochrome P-450 Enzyme System; Drug Interactions; Enzyme Activation; Female; Heme; Lipid Metabolism; Liver; Male; Microsomes, Liver; Necrosis; Organ Size; Phenobarbital; Triazoles | 1973 |
Studies on the role of heme in the regulation of delta-aminolevulinic acid synthetase during fetal hepatic development.
Topics: 5-Aminolevulinate Synthetase; Animals; Cycloheximide; Endoplasmic Reticulum; Fetus; Heme; Liver; Microsomes, Liver; Protein Biosynthesis; Rats; Rats, Inbred Strains; Time Factors; Triazoles | 1974 |
The formation of biliverdin by chicken macrophages in tissue culture. Observations on the effect of inhibitors.
Topics: Acetanilides; Animals; Ascorbic Acid; Azides; Bile Pigments; Carbon Monoxide; Chickens; Chloramphenicol; Culture Techniques; Cyanides; Cycloheximide; Dactinomycin; Erythrocytes; Ethylmaleimide; Female; Heme; Hydrogen Peroxide; Macrophages; Metabolism; Microscopy, Phase-Contrast; Mitomycins; Phagocytosis; Phenobarbital; Proadifen; Quinacrine; Spectrophotometry; Spectrum Analysis; Stimulation, Chemical; Triazoles | 1970 |
Reaction of 3-amino-1:2:4-triazole with bovine liver catalase and human erythrocyte catalase.
Topics: Adenosine Monophosphate; Amines; Amino Acids; Animals; Catalase; Cattle; Chemical Phenomena; Chemistry; Erythrocytes; Heme; Histidine; Humans; Hydrogen Peroxide; Liver; Methods; Protein Binding; Rats; Rats, Inbred Strains; Time Factors; Triazoles | 1972 |
[Studies in the nature of ligand receptor relations in methemoglobin complexes with imidazols,1,2,4-triazol and pyridines].
Topics: Animals; Binding Sites; Chromatography, Gel; Diptera; Fishes; Heme; Horses; Humans; Hydrogen-Ion Concentration; Imidazoles; In Vitro Techniques; Methemoglobin; Methods; Protein Binding; Pyridines; Spectrophotometry; Triazoles | 1972 |
A comparison of some properties of microsomal cytochrome P-450 from normal, methylcholanthrene-, and phenobarbital-treated rats.
Topics: 1-Propanol; Amines; Animals; Chemical Phenomena; Chemistry; Chlorides; Cycloheximide; Cytochromes; Fasting; Fatty Alcohols; Heme; Hydrogen-Ion Concentration; Kinetics; Male; Mathematics; Mercury; Methylcholanthrene; Microsomes, Liver; Nitriles; Oxidation-Reduction; Phenobarbital; Potassium; Protein Biosynthesis; Rats; Spectrophotometry; Sulfites; Thiocyanates; Triazoles | 1971 |
Effect of drugs on heme synthesis in the liver.
Topics: Acyltransferases; Animals; Benzopyrenes; Cytochromes; Depression, Chemical; Glycine; Heme; Lead; Levulinic Acids; Liver; Lyases; Microsomes, Liver; Mitochondria; Oxidoreductases; Phenobarbital; Pyridines; Rats; Stimulation, Chemical; Succinates; Triazoles | 1971 |
[Spectrophotometric studies on the influence of pyridine derivatives on the NH acidity of heme-coordinated imidazole and 1,2,4-triazole].
Topics: Chemical Phenomena; Chemistry; Heme; Imidazoles; Pyridines; Spectrophotometry; Triazoles | 1967 |
[Spectrophotometric studies on the NH-acidity of hemin-diethylester-imidazoles and 1,2,4-triazole].
Topics: Amines; Animals; Diptera; Heme; Hydrogen-Ion Concentration; Imidazoles; Methemoglobin; Spectrophotometry; Triazoles | 1967 |
The nonerythropoietic component of early bilirubin.
Topics: Amides; Amino Acids; Animals; Bile Ducts; Biliary Fistula; Bilirubin; Carbon Isotopes; Catalase; Cycloheximide; Cytochromes; Erythropoiesis; Glycine; Heme; Infusions, Parenteral; Kidney; Lead Poisoning; Levulinic Acids; Male; Nephrectomy; Phenobarbital; Porphyrins; Protein Biosynthesis; Rats; Triazoles | 1968 |
[Spectral and chemical behavior of hemin diethylester and its complexes with imidazole and 1,2,4-triazole derivatives in anhydrous dimethylsulfoxide].
Topics: Animals; Biochemical Phenomena; Biochemistry; Cattle; Dimethyl Sulfoxide; Esters; Ethanol; Heme; Hydrogen-Ion Concentration; Imidazoles; Mathematics; Spectrophotometry; Spectrum Analysis; Triazoles | 1968 |
Ligand-protein interactions in imidazole and 1,2,4-triazole complexes of methaemoglobin from Chironomus plumosus.
Topics: Animals; Chemical Phenomena; Chemistry, Physical; Chromatography, Gel; Freezing; Heme; Hydrogen-Ion Concentration; Imidazoles; Macromolecular Substances; Methemoglobin; Models, Chemical; Protein Binding; Receptors, Drug; Spectrophotometry; Triazoles | 1967 |
3-Amino-1,2,4-triazole is an inhibitor of protein synthesis on mitoribosomes in Neurospora crassa.
Topics: Amitrole; Chloramphenicol; Fungal Proteins; Heme; Mitochondria; Neurospora; Neurospora crassa; Ribosomes; Triazoles | 1980 |
Effect of cobalt chloride and 3-amino-1,2,4-triazole on the induction of cytochrome P-450 synthesis by phenobarbitone in rat liver.
Topics: Amitrole; Animals; Cobalt; Cytochrome P-450 Enzyme System; Enzyme Induction; Heme; In Vitro Techniques; Male; Microsomes, Liver; Phenobarbital; Protein Biosynthesis; Rats; Triazoles | 1983 |
Autocatalytic alkylation of the cytochrome P-450 prosthetic haem group by 1-aminobenzotriazole. Isolation of an NN-bridged benzyne-protoporphyrin IX adduct.
Topics: Alkylation; Animals; Cytochrome P-450 Enzyme Inhibitors; Cytochromes; Cytochromes b5; Heme; In Vitro Techniques; Macromolecular Substances; Male; Microsomes, Liver; Protoporphyrins; Rats; Rats, Inbred Strains; Spectrophotometry; Triazoles | 1981 |
Significance of glycine 478 in the metabolism of N-benzyl-1-aminobenzotriazole to reactive intermediates by cytochrome P450 2B1.
Topics: Animals; Binding Sites; Chromatography, High Pressure Liquid; Cytochrome P-450 CYP2B1; Glycine; Heme; Magnetic Resonance Spectroscopy; Male; Mass Spectrometry; Microsomes, Liver; Models, Chemical; Models, Molecular; Mutagenesis, Site-Directed; Rats; Rats, Inbred F344; Rats, Wistar; Triazoles | 1997 |
Lack of mechanism-based inactivation of rat hepatic microsomal cytochromes P450 by doxorubicin.
Topics: Animals; Antibiotics, Antineoplastic; Carbon Tetrachloride; Cytochrome P-450 Enzyme System; Doxorubicin; Enzyme Activation; Heme; Lipid Peroxidation; Male; Microsomes, Liver; NADH, NADPH Oxidoreductases; Rats; Rats, Inbred F344; Triazoles | 1999 |
Visible spectra of type II cytochrome P450-drug complexes: evidence that "incomplete" heme coordination is common.
Topics: Aniline Compounds; Aryl Hydrocarbon Hydroxylases; Benzodioxoles; Binding Sites; Cytochrome P-450 CYP2C9; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Enzyme Inhibitors; Fluconazole; Heme; Humans; Imidazoles; Itraconazole; Kinetics; Ligands; Light; Models, Chemical; Molecular Structure; NADP; Nonlinear Dynamics; Protein Binding; Pyrimidines; Recombinant Proteins; Reference Standards; Regression Analysis; Spectrum Analysis; Sulfaphenazole; Triazoles | 2007 |
Direct spectroscopic evidence for binding of anastrozole to the iron heme of human aromatase. Peering into the mechanism of aromatase inhibition.
Topics: Anastrozole; Aromatase; Aromatase Inhibitors; Binding Sites; Computer Simulation; Electron Spin Resonance Spectroscopy; Heme; Humans; Iron; Nitriles; Quantum Theory; Triazoles | 2011 |
Stereospecific metabolism of itraconazole by CYP3A4: dioxolane ring scission of azole antifungals.
Topics: Antifungal Agents; Azoles; Binding Sites; Catalytic Domain; Cytochrome P-450 CYP3A; Cytochrome P-450 CYP3A Inhibitors; Dioxolanes; Female; Heme; Humans; Hydroxylation; Iron; Itraconazole; Male; Metabolic Networks and Pathways; Midazolam; Stereoisomerism; Triazoles | 2012 |
1,2,3-Triazole-heme interactions in cytochrome P450: functionally competent triazole-water-heme complexes.
Topics: Click Chemistry; Cytochrome P-450 CYP3A; Cytochrome P-450 CYP3A Inhibitors; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Electron Spin Resonance Spectroscopy; Ethinyl Estradiol; Heme; Imidazoles; Isomerism; Kinetics; Magnetic Resonance Spectroscopy; Protein Binding; Quantum Theory; Thermodynamics; Triazoles; Water | 2012 |
[Peripheral mechanisms of action of oxatriazolium-5-olate derivative 3-(3-[1,2,4]-triazolo)oxatriazolium-5-olate in spontaneously hypertensive rats].
Topics: Animals; Arteries; Guanylate Cyclase; Heme; Male; Nitric Oxide; Nitroprusside; Oxadiazoles; Phenylephrine; Quinoxalines; Rats; Rats, Inbred SHR; Rats, Wistar; Tail; Tissue Culture Techniques; Triazoles; Vasoconstrictor Agents; Vasodilation; Vasodilator Agents | 2012 |
[Disturbances of oxygen-dependent processes in periodontal tissues under prolonged immobilization stress and ways of their pharmacological correction].
Topics: Adrenal Glands; Animals; Antioxidants; Cell Respiration; Flavin-Adenine Dinucleotide; Gingiva; Heme; Immobilization; Lipid Peroxidation; Male; Mitochondria; NAD; Organ Size; Oxidation-Reduction; Oxygen; Oxygen Consumption; Periodontium; Rats; Rats, Wistar; Stress, Physiological; Thymus Gland; Triazoles | 2013 |
Inhibitory effects of deferasirox on the structure and function of bovine liver catalase: a spectroscopic and theoretical study.
Topics: Animals; Benzoates; Binding, Competitive; Catalase; Catalytic Domain; Cattle; Circular Dichroism; Deferasirox; Enzyme Inhibitors; Heme; Hydrophobic and Hydrophilic Interactions; Iron; Iron Chelating Agents; Kinetics; Liver; Molecular Docking Simulation; Protein Binding; Protein Structure, Secondary; Solutions; Spectrometry, Fluorescence; Temperature; Thermodynamics; Triazoles; Tryptophan | 2015 |
Mitochondrial dysfunctions trigger the calcium signaling-dependent fungal multidrug resistance.
Topics: Alkyl and Aryl Transferases; Antifungal Agents; Aspergillus fumigatus; Calcium Chelating Agents; Calcium Signaling; Chitin Synthase; Drug Resistance, Fungal; Fungal Proteins; Gene Expression Regulation, Fungal; Heme; Humans; Membrane Proteins; Mitochondria; Mitochondrial Diseases; Phosphoprotein Phosphatases; Reactive Oxygen Species; Transcription Factors; Triazoles | 2020 |
Structure-based optimization of type III indoleamine 2,3-dioxygenase 1 (IDO1) inhibitors.
Topics: Enzyme Inhibitors; Heme; Indoleamine-Pyrrole 2,3,-Dioxygenase; Triazoles | 2022 |