triazoles and gsk1210151a

Topics: Animals; Antineoplastic Agents; Azepines; Cell Cycle Proteins; Cell Line, Tumor; Discoidin Domain Receptor 1; DNA Methylation; Drug Resistance, Neoplasm; Drug Synergism; Enhancer Elements, Genetic; Epigenesis, Genetic; Female; Heterocyclic Compounds, 4 or More Rings; Humans; MAP Kinase Kinase 1; MAP Kinase Kinase 2; Mice, Inbred BALB C; Mice, SCID; Molecular Targeted Therapy; Nuclear Proteins; Positive Transcriptional Elongation Factor B; Pyridones; Pyrimidinones; RNA Interference; Transcription Factors; Triazoles; Triple Negative Breast Neoplasms; Xenograft Model Antitumor Assays

Topics: Azepines; Benzodiazepines; CD4-Positive T-Lymphocytes; Cell Cycle Proteins; Cells, Cultured; HEK293 Cells; Heterocyclic Compounds, 4 or More Rings; HIV Infections; HIV-1; Humans; Jurkat Cells; Nuclear Proteins; Positive Transcriptional Elongation Factor B; Promoter Regions, Genetic; Protein Serine-Threonine Kinases; RNA Interference; RNA, Small Interfering; tat Gene Products, Human Immunodeficiency Virus; Transcription Factors; Transcription, Genetic; Triazoles; Virus Latency

Topics: Animals; Antineoplastic Agents; Apoptosis; Azepines; Cell Cycle Checkpoints; Cell Cycle Proteins; Cell Line, Tumor; Cell Nucleus; Cell Proliferation; Cell Survival; Cellular Senescence; Disease Models, Animal; Dose-Response Relationship, Drug; Female; Gene Expression Regulation, Neoplastic; Herpesvirus 8, Human; Heterocyclic Compounds, 4 or More Rings; Humans; Inhibitory Concentration 50; Lymphoma, Primary Effusion; Nuclear Proteins; Protein Binding; Protein Transport; Proto-Oncogene Proteins c-myc; Transcription Factors; Transcription, Genetic; Triazoles; Tumor Burden; Virus Replication; Xenograft Model Antitumor Assays

Topics: Apoptosis; Azepines; Cell Line, Tumor; Cell Proliferation; Drug Resistance, Neoplasm; Epithelial-Mesenchymal Transition; Gene Expression Regulation, Neoplastic; Heterocyclic Compounds, 4 or More Rings; Humans; Kruppel-Like Transcription Factors; Nuclear Proteins; Pancreatic Neoplasms; Proto-Oncogene Proteins c-myc; Signal Transduction; Transcriptional Activation; Triazoles; Xenograft Model Antitumor Assays; Zinc Finger Protein Gli2

Topics: Animals; Azepines; Biliary Tract; Cell Line; Cell Proliferation; Cell Transdifferentiation; Epithelial Cells; Hepatocytes; Heterocyclic Compounds, 4 or More Rings; Liver; Liver Regeneration; Mice; Organ Size; Transcription Factors; Transcriptional Activation; Triazoles; Zebrafish

Topics: Animals; Antineoplastic Agents; Azepines; Carcinoma; Cell Line, Tumor; Down-Regulation; Female; Forkhead Box Protein M1; Heterocyclic Compounds, 4 or More Rings; Humans; Mice; Mice, Inbred BALB C; Mice, Nude; Nuclear Proteins; Ovarian Neoplasms; Pteridines; Transcription Factors; Triazoles

Topics: Antineoplastic Agents; Azepines; Cell Line, Tumor; Cell Proliferation; Down-Regulation; Gene Expression Regulation, Neoplastic; Heterocyclic Compounds, 4 or More Rings; Humans; Molecular Targeted Therapy; Multiple Myeloma; N-Myc Proto-Oncogene Protein; Protein Domains; Proto-Oncogene Proteins c-myc; Triazoles

Topics: Azepines; Cell Line, Tumor; Cell Proliferation; DNA-Binding Proteins; Gene Expression Regulation, Neoplastic; Heterocyclic Compounds, 4 or More Rings; Histones; Humans; Methylation; Neoplasm Proteins; Neuroblastoma; Nuclear Matrix-Associated Proteins; Octamer Transcription Factors; Prognosis; Promoter Regions, Genetic; Protein Binding; RNA Interference; RNA-Binding Proteins; RNA, Long Noncoding; RNA, Messenger; RNA, Small Interfering; Triazoles

Topics: Animals; Azepines; Carcinoma, Pancreatic Ductal; Cell Cycle Proteins; Cell Line, Tumor; Collagen Type I; Gene Expression Regulation, Neoplastic; Heterocyclic Compounds, 4 or More Rings; Humans; Mice; Nuclear Proteins; Pancreatic Neoplasms; Pancreatic Stellate Cells; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins c-fos; Proto-Oncogene Proteins p21(ras); RNA-Binding Proteins; Transcription Factors; Triazoles; Xenograft Model Antitumor Assays

Topics: Animals; Azepines; B-Lymphocytes; Cell Cycle Proteins; Cell Line; Cell Proliferation; Dose-Response Relationship, Drug; Epigenesis, Genetic; Gene Expression Regulation; Heterocyclic Compounds, 4 or More Rings; Humans; Immunoglobulin G; Mice; Nuclear Proteins; Organic Cation Transport Proteins; Organic Cation Transporter 2; Promoter Regions, Genetic; Transcription Factors; Triazoles

Topics: Antineoplastic Agents; Azepines; Benzodiazepines; Citric Acid Cycle; CRISPR-Cas Systems; Dehydroepiandrosterone; Fumarates; Gene Knockout Techniques; Glucosephosphate Dehydrogenase; Glycolysis; HCT116 Cells; Heterocyclic Compounds, 4 or More Rings; Humans; Isoenzymes; L-Lactate Dehydrogenase; Lactate Dehydrogenase 5; Metabolomics; Mitochondria; Mutation; Neoplasms; Oxygen Consumption; Phenformin; Phosphoglycerate Dehydrogenase; Proto-Oncogene Proteins c-myc; RNA Interference; RNA, Small Interfering; Succinate Dehydrogenase; Succinic Acid; Triazoles

Topics: Acetanilides; Animals; Azepines; Blotting, Southern; Cell Cycle Proteins; Cell Line; Dose-Response Relationship, Drug; Fibroblasts; Gene Expression; HeLa Cells; Heterocyclic Compounds, 3-Ring; Heterocyclic Compounds, 4 or More Rings; Humans; In Situ Hybridization, Fluorescence; Mice; Morpholines; Nuclear Proteins; Pyrones; RNA Interference; Telomerase; Telomere; Telomere Homeostasis; Telomere Shortening; Transcription Factors; Triazoles

Topics: Antineoplastic Agents; Apoptosis; Azepines; Benzodiazepines; Cell Differentiation; Cell Line, Tumor; Cell Proliferation; Cyclin-Dependent Kinase Inhibitor p21; Gene Expression Regulation, Neoplastic; Heterocyclic Compounds, 4 or More Rings; Humans; MicroRNAs; Phosphorylation; STAT3 Transcription Factor; Thyroid Carcinoma, Anaplastic; Thyroid Neoplasms; Triazoles

Topics: A549 Cells; Animals; Azepines; Carcinoma, Non-Small-Cell Lung; Cell Cycle Proteins; Cell Line, Tumor; Disease Models, Animal; Down-Regulation; Eukaryotic Initiation Factor-4E; Heterocyclic Compounds, 4 or More Rings; Humans; Lung Neoplasms; Mice; Mice, Nude; Molecular Targeted Therapy; Nuclear Proteins; Random Allocation; Transcription Factors; Transfection; Triazoles; Xenograft Model Antitumor Assays

Topics: Animals; Azepines; Basic Helix-Loop-Helix Transcription Factors; Cell Differentiation; Cell Proliferation; Heterocyclic Compounds, 4 or More Rings; Humans; Induced Pluripotent Stem Cells; Insulin-Secreting Cells; Islets of Langerhans; Mice; Nerve Tissue Proteins; Proteins; Signal Transduction; Triazoles

Topics: Animals; Azepines; Cytokines; Epithelial Cells; Extracellular Signal-Regulated MAP Kinases; Fibroblasts; Gingiva; Heterocyclic Compounds, 4 or More Rings; Humans; Inflammation; Mice; Periodontitis; Porphyromonas gingivalis; Triazoles

Topics: Antineoplastic Combined Chemotherapy Protocols; Azepines; Benzodiazepines; Cell Death; Cell Line, Tumor; Drug Synergism; Heterocyclic Compounds, 4 or More Rings; Humans; NF-E2-Related Factor 1; Oligopeptides; Proteasome Inhibitors; Triazoles; Unfolded Protein Response

Topics: Animals; Azepines; Carotid Artery Injuries; Cell Cycle Checkpoints; Cell Cycle Proteins; Cell Proliferation; Cells, Cultured; Coronary Vessels; Cyclin-Dependent Kinase Inhibitor p21; Disease Models, Animal; Forkhead Box Protein O1; Heterocyclic Compounds, 4 or More Rings; Humans; Male; Mice, Inbred C57BL; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; Neointima; Nuclear Proteins; Proteins; Signal Transduction; Transcription Factors; Triazoles; Vascular System Injuries

Topics: A549 Cells; Activating Transcription Factor 2; Animals; Antineoplastic Agents; Azepines; Breast Neoplasms; Cell Line, Tumor; Drug Resistance, Neoplasm; Feedback, Physiological; Female; Ferroptosis; HeLa Cells; Heterocyclic Compounds, 4 or More Rings; Humans; MAP Kinase Signaling System; Mice; Mice, Nude; Neoplasms; NF-E2-Related Factor 2; Proteins; RNA, Messenger; Triazoles; Xenograft Model Antitumor Assays

Topics: Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Azepines; Carcinoma, Non-Small-Cell Lung; Cell Line, Tumor; Cell Proliferation; Cisplatin; Drug Synergism; Epigenesis, Genetic; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Gene Knockdown Techniques; Heterocyclic Compounds, 4 or More Rings; Humans; Kaplan-Meier Estimate; Lung Neoplasms; Paclitaxel; Prognosis; Signal Transduction; Transcription Factors; Triazoles