Page last updated: 2024-08-24

triazoles and gea 3162

triazoles has been researched along with gea 3162 in 36 studies

Research

Studies (36)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's20 (55.56)18.2507
2000's14 (38.89)29.6817
2010's2 (5.56)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Karp, M; Virta, M; Vuorinen, P1
Jaakkola, O; Malo-Ranta, U; Metsä-Ketelä, T; Moilanen, E; Nikkari, T; Vuorinen, P; Ylä-Herttuala, S1
Kankaanranta, H; Metsä-Ketelä, T; Moilanen, E; Vapaatalo, H; Vuorinen, P1
Corell, T; Holm, P; Kankaanranta, H; Karup, G; Metsä-Ketelä, T; Moilanen, E; Pedersen, SB; Petersson, AS; Rydell, E; Vuorinen, P; Wennmalm, A1
Nurminen, ML; Vapaatalo, H1
Metsä-Ketelä, T; Moilanen, E; Vilpo, JA; Vilpo, LM; Vuorinen, P1
Cuthbertson, BH; Galley, HF; Webster, NR2
Alanko, J; Lähteenmäki, TA; Sievi, E; Vapaatalo, H; Vuorinen, P1
Dézsi, L; Metsä-Ketelä, T; Monos, E; Szekeres, M1
Kankaanranta, H; Kosonen, O; Moilanen, E; Vuorinen, P1
Baker, R; Botsford, JL; Navarez, J; Riley, R; Rivera, J; Wright, T1
Holm, P; Kankaanranta, H; Metsä-Ketelä, T; Moilanen, E1
Kankaanranta, H; Kosonen, O; Lähde, M; Moilanen, E; Vuorinen, P; Ylitalo, P1
Lähteenmäki, T; Sievi, E; Vapaatalo, H1
Blaylock, MG; Cuthbertson, BH; Ferguson, NR; Galley, HF; Webster, NR1
Favre, CJ; Gill, DL; Ma, HT; Stone, MR; Ufret-Vincenty, CA1
Annala, K; Asmawi, MZ; Kankaanranta, H; Moilanen, E; Rahkonen, P1
Kankaanranta, H; Kosonen, O; Malo-Ranta, U; Moilanen, E1
Favre, CJ; Gill, DL; Ma, HT; Patterson, RL; Stone, MR1
Chilvers, ER; Haslett, C; Murray, J; Rahman, I; Rossi, AG; Ward, C; Wong, TH1
Eizirik, DL; Ling, Z; Pipeleers, DG; Van de Casteele, M1
Gill, DL; Ma, HT; Patterson, RL; van Rossum, DB1
Jacobson, KL; Ott, SM; Singh, JC; Watson, EL1
Haslett, C; Megson, IL; Rossi, AG; Taylor, EL1
Diener, M; Kocks, SL; Schultheiss, G; Seip, G1
Wang, JP1
DiJulio, DH; Jacobson, KL; Singh, JC; Watson, EL1
Dal Rio, FP; Haslett, C; Megson, IL; Rossi, AG; Shaw, CA; Taylor, EL1
Banasik, M; Klink, M; Majewska, E; Sulowska, Z; Tchórzewski, H1
Chen, YS; Hsu, MF; Huang, LJ; Kuo, SC; Tsao, LT; Wang, JP1
Kamikawa, Y; Kojima, S; Ohno, Y; Sasaki, K; Sunagawa, M; Uchida, K1
Harlan, JM; Li, JT; Rossi, AG; Taylor, EL; Tupper, JC; Winn, RK1
Diener, M; Rehn, M; Sitmo, M1
Blackmore, PF1
Amin, A; Hussain, R; Johannesson, M; Oliynyk, I; Roomans, GM1

Other Studies

36 other study(ies) available for triazoles and gea 3162

ArticleYear
Nitric oxide donor-mediated killing of bioluminescent Escherichia coli.
    Antimicrobial agents and chemotherapy, 1994, Volume: 38, Issue:12

    Topics: Cloning, Molecular; Escherichia coli; Luciferases; Luminescent Measurements; Molsidomine; Nitric Oxide; Triazoles

1994
Nitric oxide donor GEA 3162 inhibits endothelial cell-mediated oxidation of low density lipoprotein.
    FEBS letters, 1994, Jan-10, Volume: 337, Issue:2

    Topics: Animals; Aorta; Cells, Cultured; Electrophoresis, Polyacrylamide Gel; Endothelium, Vascular; Humans; Immunoblotting; Lipoproteins, LDL; Macrophages, Peritoneal; Mice; Nitric Oxide; Oxidation-Reduction; Rats; Triazoles

1994
Inhibition by nitric oxide-donors of human polymorphonuclear leucocyte functions.
    British journal of pharmacology, 1993, Volume: 109, Issue:3

    Topics: Cell Degranulation; Chemotaxis, Leukocyte; Cyclic AMP; Cyclic GMP; Glucuronidase; Humans; In Vitro Techniques; Leukotriene B4; Luminescent Measurements; Molsidomine; Neutrophils; Nitric Oxide; Penicillamine; S-Nitroso-N-Acetylpenicillamine; Superoxides; Triazoles

1993
Nitric oxide-donating properties of mesoionic 3-aryl substituted oxatriazole-5-imine derivatives.
    British journal of pharmacology, 1996, Volume: 117, Issue:3

    Topics: Blood Platelets; Chromatography, High Pressure Liquid; Cyclic GMP; Electron Spin Resonance Spectroscopy; Humans; In Vitro Techniques; Luminescent Measurements; Methemoglobin; Nitrates; Nitric Oxide; Nitrites; Oxyhemoglobins; Platelet Aggregation; Triazoles

1996
Effect of intracerebroventricular and intravenous administration of nitric oxide donors on blood pressure and heart rate in anaesthetized rats.
    British journal of pharmacology, 1996, Volume: 119, Issue:7

    Topics: Animals; Blood Pressure; Cyclic GMP; Dose-Response Relationship, Drug; Enzyme Inhibitors; Heart Rate; Injections, Intravenous; Injections, Intraventricular; Male; Molsidomine; Nitric Oxide; Nitroprusside; Platelet Aggregation Inhibitors; Rats; Rats, Wistar; Triazoles

1996
Mode of cytostatic action of mesoionic oxatriazole nitric oxide donors in proliferating human hematopoietic cells.
    Anti-cancer drug design, 1997, Volume: 12, Issue:2

    Topics: Antineoplastic Agents; Cell Division; Cell Membrane Permeability; Cell Size; DNA, Neoplasm; Hematopoietic Stem Cells; Humans; Leukemia-Lymphoma, Adult T-Cell; Molsidomine; Neoplasm Proteins; Nitric Oxide; Platelet Aggregation Inhibitors; RNA, Neoplasm; Triazoles; Tumor Cells, Cultured

1997
Effect of exogenous nitric oxide and superoxide on interleukin-8 from human polymorphonuclear leucocytes.
    British journal of anaesthesia, 1997, Volume: 78, Issue:6

    Topics: Cell Culture Techniques; Dose-Response Relationship, Drug; Humans; Interleukin-8; Lipopolysaccharides; Molsidomine; Neutrophil Activation; Neutrophils; Nitric Oxide; Platelet Aggregation Inhibitors; Superoxides; Triazoles

1997
Nitric oxide as a regulator of prostacyclin synthesis in cultured rat heart endothelial cells.
    Arzneimittel-Forschung, 1997, Volume: 47, Issue:10

    Topics: 6-Ketoprostaglandin F1 alpha; Animals; Cells, Cultured; Endothelium, Vascular; Enzyme Inhibitors; Epoprostenol; Female; Guanylate Cyclase; Male; Molsidomine; Nitric Oxide; Nitric Oxide Synthase; Platelet Aggregation Inhibitors; Rats; Rats, Wistar; Triazoles; Vasodilator Agents

1997
Effect of a new nitric oxide donor on the biomechanical performance of the isolated ischaemic rat heart.
    Acta physiologica Scandinavica, 1997, Volume: 161, Issue:1

    Topics: Animals; Biomechanical Phenomena; Bradykinin; Heart; In Vitro Techniques; Male; Myocardial Ischemia; Nitric Oxide; Platelet Aggregation Inhibitors; Rats; Rats, Wistar; Reperfusion Injury; Triazoles; Vascular Resistance; Vasodilator Agents; Ventricular Function, Left

1997
Inhibition of human lymphocyte proliferation by nitric oxide-releasing oxatriazole derivatives.
    European journal of pharmacology, 1997, Oct-15, Volume: 337, Issue:1

    Topics: Cell Division; Cell Separation; Concanavalin A; Cyclic GMP; Erythrocytes; Humans; In Vitro Techniques; Lymphocytes; Nitric Oxide; Penicillamine; Platelet Aggregation Inhibitors; S-Nitroso-N-Acetylpenicillamine; Triazoles

1997
Assay for toxic chemicals using bacteria.
    Bulletin of environmental contamination and toxicology, 1997, Volume: 59, Issue:6

    Topics: Bacteria; Coloring Agents; Culture Media; Minerals; Oxidation-Reduction; Platelet Aggregation Inhibitors; Rhizobium; Tetrazolium Salts; Thiazoles; Toxicity Tests; Triazoles

1997
The effects of nitric oxide and peroxynitrite on interleukin-8 and elastase from lipopolysaccharide-stimulated whole blood.
    Anesthesia and analgesia, 1998, Volume: 86, Issue:2

    Topics: Free Radical Scavengers; Humans; In Vitro Techniques; Interleukin-8; Leukocyte Elastase; Lipopolysaccharides; Male; Molsidomine; Nitrates; Nitric Oxide; Triazoles

1998
Radical releasing properties of nitric oxide donors GEA 3162, SIN-1 and S-nitroso-N-acetylpenicillamine.
    European journal of pharmacology, 1998, Apr-03, Volume: 346, Issue:1

    Topics: Molsidomine; Nitric Oxide; Oxygen; Penicillamine; Superoxides; Triazoles; Tyrosine

1998
Nitric oxide-releasing oxatriazole derivatives inhibit human lymphocyte proliferation by a cyclic GMP-independent mechanism.
    The Journal of pharmacology and experimental therapeutics, 1998, Volume: 286, Issue:1

    Topics: 1-Methyl-3-isobutylxanthine; Cyclic GMP; Guanylate Cyclase; Humans; Lymphocyte Activation; Nitric Oxide; Triazoles

1998
Inhibitory effects of mesoionic 3-aryl substituted oxatriazole-5-imine derivatives on vascular smooth muscle cell mitogenesis and proliferation in vitro.
    British journal of pharmacology, 1998, Volume: 125, Issue:2

    Topics: Animals; Cell Division; Cells, Cultured; Cyclic GMP; DNA; Male; Molsidomine; Muscle, Smooth, Vascular; Nitric Oxide Donors; Nitrites; Penicillamine; Rats; Rats, Wistar; Signal Transduction; Triazoles; Urea

1998
The effect of nitric oxide and peroxynitrite on apoptosis in human polymorphonuclear leukocytes.
    Free radical biology & medicine, 1998, Volume: 25, Issue:6

    Topics: Annexin A5; Apoptosis; Flow Cytometry; Humans; Lipopolysaccharides; Lung; Molsidomine; Neutrophils; Nitrates; Nitric Oxide; Triazoles

1998
Ca2+ pool emptying stimulates Ca2+ entry activated by S-nitrosylation.
    The Journal of biological chemistry, 1998, Nov-20, Volume: 273, Issue:47

    Topics: Alkylating Agents; Animals; Biological Transport; Calcium; Calcium Signaling; Cells, Cultured; Cricetinae; Lung; Muscle, Smooth; Nitric Oxide; Nitrites; Nitroprusside; Nitroso Compounds; Sulfhydryl Compounds; Triazoles

1998
Effects of nitric oxide donors GEA 3162 and SIN-1 on ethanol-induced gastric ulceration in rats.
    European journal of pharmacology, 1999, Jul-28, Volume: 378, Issue:1

    Topics: Animals; Blood Pressure; Dinoprostone; Ethanol; Gastric Mucosa; Male; Molsidomine; Nitric Oxide Donors; Rats; Rats, Wistar; Stomach Ulcer; Triazoles

1999
Nitric oxide-releasing compounds inhibit neutrophil adhesion to endothelial cells.
    European journal of pharmacology, 1999, Oct-08, Volume: 382, Issue:2

    Topics: Animals; CD11 Antigens; CD18 Antigens; Cell Adhesion; Coculture Techniques; Cyclic GMP; Dose-Response Relationship, Drug; Endothelium, Vascular; Humans; Molsidomine; Neutrophils; Nitric Oxide Donors; Rabbits; Thionucleotides; Triazoles; Tumor Necrosis Factor-alpha

1999
Ca(2+) entry activated by S-nitrosylation. Relationship to store-operated ca(2+) entry.
    The Journal of biological chemistry, 1999, Dec-10, Volume: 274, Issue:50

    Topics: Animals; Barium; Calcium; Calcium Channels; Cell Line; Cricetinae; Ethylmaleimide; Kinetics; Muscle, Smooth; Nitric Oxide Donors; Nitroso Compounds; Platelet Aggregation Inhibitors; Thapsigargin; Triazoles

1999
Induction of human neutrophil apoptosis by nitric oxide donors: evidence for a caspase-dependent, cyclic-GMP-independent, mechanism.
    Biochemical pharmacology, 2000, Feb-01, Volume: 59, Issue:3

    Topics: Adult; Apoptosis; Caspases; Cyclic GMP; Free Radicals; Guanylate Cyclase; Humans; In Vitro Techniques; Inflammation; Neutrophil Activation; Neutrophils; Nitric Oxide; Nitric Oxide Donors; Reactive Oxygen Species; Triazoles

2000
Interleukin-1beta-induced alteration in a beta-cell phenotype can reduce cellular sensitivity to conditions that cause necrosis but not to cytokine-induced apoptosis.
    Diabetes, 2000, Volume: 49, Issue:3

    Topics: Alloxan; Animals; Apoptosis; Cytokines; Dose-Response Relationship, Drug; Interleukin-1; Islets of Langerhans; Male; Necrosis; Nitric Oxide Donors; Osmolar Concentration; Phenotype; Proteins; Rats; Rats, Wistar; Streptozocin; Triazoles

2000
Ca2+ entry mediated by store depletion, S-nitrosylation, and TRP3 channels. Comparison of coupling and function.
    The Journal of biological chemistry, 2000, Sep-15, Volume: 275, Issue:37

    Topics: Animals; Calcium; Calcium Channels; Cricetinae; Diglycerides; Imines; Inositol 1,4,5-Trisphosphate Receptors; Male; Receptors, Cytoplasmic and Nuclear; Triazoles; TRPC Cation Channels

2000
Nitric oxide inhibition of cAMP synthesis in parotid acini: regulation of type 5/6 adenylyl cyclase.
    Cellular signalling, 2001, Volume: 13, Issue:10

    Topics: Adenylyl Cyclases; Animals; Calcium; Cells, Cultured; Colforsin; Cyclic AMP; Cyclic GMP; Dose-Response Relationship, Drug; Enzyme Inhibitors; Isoenzymes; Isoproterenol; Mice; Nitric Oxide; Nitric Oxide Donors; Oxadiazoles; Parotid Gland; Phosphoric Diester Hydrolases; Quinoxalines; Thapsigargin; Triazoles

2001
Dissociation of DNA fragmentation from other hallmarks of apoptosis in nitric oxide-treated neutrophils: differences between individual nitric oxide donor drugs.
    Biochemical and biophysical research communications, 2001, Dec-21, Volume: 289, Issue:5

    Topics: Annexin A5; Apoptosis; DNA Fragmentation; Humans; Hydrazines; In Vitro Techniques; Intercalating Agents; Neutrophils; Nitric Oxide; Nitric Oxide Donors; Nitrogen Oxides; Propidium; Receptors, IgG; Spermine; Triazoles

2001
Ca(2+)-dependent and -independent Cl(-) secretion stimulated by the nitric oxide donor, GEA 3162, in rat colonic epithelium.
    European journal of pharmacology, 2002, May-24, Volume: 444, Issue:1-2

    Topics: Animals; Calcium; Chlorides; Colon; Nitric Oxide Donors; Patch-Clamp Techniques; Rats; Rats, Wistar; Sodium-Potassium-Exchanging ATPase; Triazoles

2002
GEA3162 stimulates Ca2+ entry in neutrophils.
    European journal of pharmacology, 2003, Jan-05, Volume: 458, Issue:3

    Topics: Adenylyl Cyclase Inhibitors; Animals; Barium; Boron Compounds; Calcium; Calcium Signaling; Calcium-Transporting ATPases; Cell Membrane Permeability; Dose-Response Relationship, Drug; Enzyme Inhibitors; Genistein; Imines; Indoles; Manganese; Marine Toxins; Neutrophils; Nitric Oxide Donors; Oxazoles; Phosphoprotein Phosphatases; Rats; Rats, Sprague-Dawley; S-Nitrosothiols; Strontium; Triazoles

2003
Arachidonic acid regulates two Ca2+ entry pathways via nitric oxide.
    Cellular signalling, 2004, Volume: 16, Issue:2

    Topics: Animals; Arachidonic Acid; Calcium; Calcium Signaling; Cells, Cultured; Cyclic GMP; Enzyme Inhibitors; Fura-2; Gadolinium; Indazoles; Mice; Nitric Oxide; Parotid Gland; Ryanodine; Tetracaine; Thapsigargin; Triazoles

2004
GEA 3162 decomposes to co-generate nitric oxide and superoxide and induces apoptosis in human neutrophils via a peroxynitrite-dependent mechanism.
    British journal of pharmacology, 2004, Volume: 143, Issue:1

    Topics: Apoptosis; Cell Separation; Electrochemistry; Electron Spin Resonance Spectroscopy; Fluorescent Dyes; Humans; In Vitro Techniques; Molsidomine; Neutrophils; Nitric Oxide; Nitric Oxide Donors; Peroxynitrous Acid; Rhodamines; Superoxides; Triazoles

2004
Flow cytometric evaluation of human neutrophil apoptosis during nitric oxide generation in vitro: the role of exogenous antioxidants.
    Mediators of inflammation, 2005, Jun-09, Volume: 2005, Issue:2

    Topics: Antioxidants; Apoptosis; Catalase; Flow Cytometry; Humans; Molsidomine; Neutrophils; Nitric Oxide; Nitric Oxide Donors; Nitroprusside; Superoxide Dismutase; Triazoles

2005
GEA3162, a nitric oxide-releasing agent, activates non-store-operated Ca2+ entry and inhibits store-operated Ca2+ entry pathways in neutrophils through thiol oxidation.
    European journal of pharmacology, 2006, Mar-27, Volume: 535, Issue:1-3

    Topics: Acetylcysteine; Actin Cytoskeleton; Animals; Calcium; Calcium Signaling; Calcium-Transporting ATPases; Chelating Agents; Dose-Response Relationship, Drug; Enzyme Inhibitors; Indoles; Male; Membrane Potentials; Mercaptoethanol; Mitochondrial Membranes; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Nitric Oxide Donors; Oxidation-Reduction; Phosphoproteins; Phosphorylation; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Sulfhydryl Compounds; Time Factors; Triazoles; Tyrosine; Unithiol

2006
The suppressant effect of GEA3162 on spontaneous serotonin release from human colonic mucosa in vitro.
    European journal of pharmacology, 2006, Nov-21, Volume: 550, Issue:1-3

    Topics: Calcium Channel Blockers; Chromatography, High Pressure Liquid; Colon; Electrochemistry; Enzyme Inhibitors; Gastrointestinal Hormones; Guanylate Cyclase; Hydroxyindoleacetic Acid; Intestinal Mucosa; Natriuretic Peptides; NG-Nitroarginine Methyl Ester; Nicardipine; Nitric Oxide Donors; Nitric Oxide Synthase; Oxadiazoles; Peroxynitrous Acid; Quinoxalines; Serotonin; Triazoles

2006
GEA 3162, a peroxynitrite donor, induces Bcl-2-sensitive, p53-independent apoptosis in murine bone marrow cells.
    Biochemical pharmacology, 2007, Oct-01, Volume: 74, Issue:7

    Topics: Animals; Apoptosis; Bone Marrow Cells; Caspases; Cell Line; Cell Survival; Dose-Response Relationship, Drug; Enzyme Activation; Mice; Mitochondria; Mitogen-Activated Protein Kinases; Nitric Oxide Donors; Proto-Oncogene Proteins c-bcl-2; Triazoles; Tumor Suppressor Protein p53

2007
Stimulation of voltage-dependent Ca2+ channels by NO at rat myenteric neurons.
    American journal of physiology. Gastrointestinal and liver physiology, 2007, Volume: 293, Issue:4

    Topics: Animals; Calcium; Calcium Channels; Immunohistochemistry; Membrane Potentials; Myenteric Plexus; Nitric Oxide; Nitric Oxide Donors; Nitroprusside; Patch-Clamp Techniques; Rats; Triazoles

2007
Biphasic effects of nitric oxide on calcium influx in human platelets.
    Thrombosis research, 2011, Volume: 127, Issue:1

    Topics: Blood Platelets; Calcium; Calcium-Transporting ATPases; Cell Adhesion Molecules; Cyclic GMP; Cyclic GMP-Dependent Protein Kinases; Dose-Response Relationship, Drug; Enzyme Inhibitors; Guanylate Cyclase; Humans; Membrane Proteins; Neoplasm Proteins; Nitric Oxide; Nitric Oxide Donors; Nitric Oxide Synthase; Nitroprusside; Phosphorylation; Stromal Interaction Molecule 1; Stromal Interaction Molecule 2; Thrombin; Time Factors; Triazoles

2011
The effect of NO-donors on chloride efflux, intracellular Ca(2+) concentration and mRNA expression of CFTR and ENaC in cystic fibrosis airway epithelial cells.
    Experimental and molecular pathology, 2013, Volume: 94, Issue:3

    Topics: Bronchi; Calcium; Cell Line; Chlorides; Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance Regulator; Epithelial Cells; Epithelial Sodium Channels; Gene Expression Regulation; Nitric Oxide Donors; RNA, Messenger; Triazoles

2013