triazoles has been researched along with g007-lk in 13 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 10 (76.92) | 24.3611 |
| 2020's | 3 (23.08) | 2.80 |
| Authors | Studies |
|---|---|
| Blake, RA; Boggs, J; Callow, M; Chan, E; Choo, E; Costa, M; Diaz, D; Firestein, R; Holsworth, DD; Korinek, V; Krauss, S; Lau, T; Machon, O; Magnuson, S; Merchant, M; Polakis, P; Sambrone, A; Schutten, M; Waaler, J | 1 |
| Brech, A; Krauss, S; Liestøl, K; Pedersen, NM; Schultz, SW; Stenmark, H; Thorvaldsen, TE; Waaler, J; Wenzel, EM | 1 |
| Chen, J; Han, X; Li, N; Li, X; Tran, MK; Wang, W | 1 |
| Baryawno, N; Calero, R; Darabi, A; Dyberg, C; Einvik, C; Johnsen, JI; Kogner, P; Kool, M; Milosevic, J; Sandén, E; Siesjö, P; Sveinbjörnsson, B; Wickström, M | 1 |
| Bandyopadhyay, G; Börgeson, E; Chi, NW; Ding, Y; Krauss, S; Mahata, SK; Mahooti, S; Phillips, SA; Shao, J; Smith, S; Waaler, J; Zhang, M; Zhong, L | 1 |
| Pedersen, NM; Stenmark, H; Thorvaldsen, TE; Wenzel, EM | 1 |
| Calvisi, DF; Chen, X; Cigliano, A; Jia, J; Liu, X; Pilo, MG; Qiao, Y; Shao, Z | 1 |
| Fujita, S; Kittaka, M; Kodama, S; Mito, T; Morita, Y; Mukai, T; Nagasu, A; Sone, T; Ueki, Y | 1 |
| Brech, A; Krauss, S; Kuiper, R; Norum, JH; Skarpen, E; Sørlie, T; Waaler, J | 1 |
| Chen, J; Chen, Z; Deng, W; Fong, LWR; Hung, MC; Jiang, W; Li, N; Li, X; Lin, SH; Neri, S; Qiao, Y; Stephan, C; Wang, Y; Ye, R; Yu, Y; Zhang, S; Zhen, Y | 1 |
| Bouslama, R; Chi, NW; Dumont, V; Krauss, S; Kuusela, S; Lehtonen, S; Linden, AM; Pirinen, E; Ramadan, UA; Rinnankoski-Tuikka, R; Waaler, J; Wang, H | 1 |
| Aizenshtadt, A; Brinch, SA; Bøe, SL; Corthay, A; Dybing, E; Fauskanger, M; Hammarström, C; Heintz, KM; Hovig, E; Krauss, S; Lund, K; Lycke, M; Mygland, L; Nygaard, V; Olsen, PA; Solberg, NT; Strand, MF; Tveita, A; Waaler, J | 1 |
| Beilhack, A; Chen, CW; Dees, C; Distler, JHW; Ditschkowski, M; Dreißigacker, K; Herr, W; Karrer, S; Krauss, S; Mackensen, A; Matei, AE; Meng, X; Schett, G; Shen, L; Spriewald, BM; Tran-Manh, C; Trinh-Minh, T; Winkler, J; Wolff, D; Zhang, Y; Zhu, H; Ziemer, M | 1 |
13 other study(ies) available for triazoles and g007-lk
| Article | Year |
|---|---|
A novel tankyrase small-molecule inhibitor suppresses APC mutation-driven colorectal tumor growth.
Topics: Animals; Axin Protein; beta Catenin; Cell Line, Tumor; Cell Proliferation; Colorectal Neoplasms; Enzyme Inhibitors; Genes, APC; Humans; Mice; Mutation; Piperidines; Spheroids, Cellular; Sulfones; Tankyrases; Triazoles; Wnt Signaling Pathway; Xenograft Model Antitumor Assays | 2013 |
Structure, Dynamics, and Functionality of Tankyrase Inhibitor-Induced Degradasomes.
Topics: Axin Signaling Complex; Cell Line, Tumor; Colonic Neoplasms; Humans; Sulfones; Tankyrases; Triazoles; Wnt Signaling Pathway | 2015 |
Tankyrase Inhibitors Target YAP by Stabilizing Angiomotin Family Proteins.
Topics: Adaptor Proteins, Signal Transducing; Angiomotins; Enzyme Inhibitors; HEK293 Cells; Heterocyclic Compounds, 3-Ring; Humans; Intercellular Signaling Peptides and Proteins; MCF-7 Cells; Membrane Proteins; Microfilament Proteins; Phosphoproteins; Protein Binding; Protein Stability; Proteolysis; Sulfones; Tankyrases; Transcription Factors; Triazoles; Ubiquitin-Protein Ligases; YAP-Signaling Proteins | 2015 |
Wnt/β-catenin pathway regulates MGMT gene expression in cancer and inhibition of Wnt signalling prevents chemoresistance.
Topics: Animals; Antineoplastic Agents; Benzeneacetamides; beta Catenin; Brain Neoplasms; Camptothecin; Celecoxib; Cisplatin; Colorectal Neoplasms; Dacarbazine; DNA Modification Methylases; DNA Repair Enzymes; Doxorubicin; Drug Resistance, Neoplasm; Flow Cytometry; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Glioma; Glucose-6-Phosphate Isomerase; Heterocyclic Compounds, 3-Ring; Humans; Immunoblotting; Immunohistochemistry; Irinotecan; Medulloblastoma; Mice; Neoplasm Transplantation; Neoplasms; Neuroblastoma; Pyrans; Pyrazines; Pyridines; Real-Time Polymerase Chain Reaction; Sulfones; Temozolomide; Triazoles; Tumor Suppressor Proteins; Vincristine; Wnt Proteins; Wnt Signaling Pathway | 2015 |
The PARsylation activity of tankyrase in adipose tissue modulates systemic glucose metabolism in mice.
Topics: Adipose Tissue; Animals; Blood Glucose; Carbohydrate Metabolism; Female; Glucose; Male; Mice; Sulfones; Tankyrases; Triazoles | 2016 |
Differential Roles of AXIN1 and AXIN2 in Tankyrase Inhibitor-Induced Formation of Degradasomes and β-Catenin Degradation.
Topics: Axin Protein; beta Catenin; Blotting, Western; Cell Line, Tumor; Colorectal Neoplasms; Cytoplasmic Vesicles; Humans; Proteasome Endopeptidase Complex; Proteolysis; Sulfones; Tankyrases; Triazoles; Wnt Signaling Pathway | 2017 |
Tankyrase inhibitors suppress hepatocellular carcinoma cell growth via modulating the Hippo cascade.
Topics: Adaptor Proteins, Signal Transducing; Angiomotins; Antineoplastic Agents; Apoptosis; Blotting, Western; Carcinoma, Hepatocellular; Carrier Proteins; Cell Line, Tumor; Cell Proliferation; Dose-Response Relationship, Drug; Heterocyclic Compounds, 3-Ring; Humans; Liver Neoplasms; Membrane Proteins; Phosphoproteins; Real-Time Polymerase Chain Reaction; Sulfones; Tankyrases; Transcription Factors; Triazoles; YAP-Signaling Proteins | 2017 |
Pharmacological inhibition of tankyrase induces bone loss in mice by increasing osteoclastogenesis.
Topics: Adaptor Proteins, Signal Transducing; Animals; Bone Marrow Cells; Heterocyclic Compounds, 3-Ring; Humans; Imides; Male; Mice; Mice, Inbred C57BL; NFATC Transcription Factors; Osteoclasts; Osteogenesis; Quinolines; RANK Ligand; Sulfones; Tankyrases; Triazoles | 2018 |
The tankyrase inhibitor G007-LK inhibits small intestine LGR5
Topics: Animals; Cell Proliferation; Duodenum; Fluorescent Antibody Technique; Immunohistochemistry; Intestine, Small; Male; Mice; Mice, Transgenic; Microscopy, Confocal; Receptors, G-Protein-Coupled; Stem Cells; Sulfones; Tankyrases; Triazoles | 2018 |
Tankyrase disrupts metabolic homeostasis and promotes tumorigenesis by inhibiting LKB1-AMPK signalling.
Topics: AMP-Activated Protein Kinase Kinases; AMP-Activated Protein Kinases; Animals; Carcinogenesis; Cell Line, Tumor; Energy Metabolism; Enzyme Inhibitors; HeLa Cells; Homeostasis; Humans; MCF-7 Cells; Mice, Inbred BALB C; Mice, Inbred C57BL; Mice, Nude; Neoplasms; para-Aminobenzoates; Protein Serine-Threonine Kinases; Signal Transduction; Sulfones; Tankyrases; Triazoles; Xenograft Model Antitumor Assays | 2019 |
Tankyrase inhibition ameliorates lipid disorder via suppression of PGC-1α PARylation in db/db mice.
Topics: Abdominal Fat; Adipose Tissue, White; Animals; Body Weight; Diabetes Mellitus, Type 2; Dyslipidemias; Liver; Male; Mice; Mice, Inbred C57BL; Mice, Inbred Strains; Obesity; Oxidation-Reduction; Peroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alpha; Poly ADP Ribosylation; Sulfones; Tankyrases; Triazoles | 2020 |
Tankyrase inhibition sensitizes melanoma to PD-1 immune checkpoint blockade in syngeneic mouse models.
Topics: Adaptor Proteins, Signal Transducing; Animals; Antineoplastic Combined Chemotherapy Protocols; beta Catenin; CD8-Positive T-Lymphocytes; Cytotoxicity, Immunologic; Drug Synergism; Enzyme Inhibitors; Female; HEK293 Cells; Humans; Immune Checkpoint Inhibitors; Interferon-gamma; Lymphocytes, Tumor-Infiltrating; Melanoma, Experimental; Mice, Inbred C57BL; Mice, Inbred DBA; Mice, Transgenic; Programmed Cell Death 1 Receptor; Skin Neoplasms; Sulfones; Tankyrases; Triazoles; Tumor Burden; Wnt Signaling Pathway; YAP-Signaling Proteins | 2020 |
Targeting of canonical WNT signaling ameliorates experimental sclerodermatous chronic graft-versus-host disease.
Topics: Animals; Anti-Bacterial Agents; Female; Fibroblasts; Graft vs Host Disease; Hematopoietic Stem Cell Transplantation; Humans; Male; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Middle Aged; Pyrans; Pyrvinium Compounds; Scleroderma, Systemic; Sulfones; Triazoles; Wnt Signaling Pathway | 2021 |