triazoles has been researched along with estrone in 54 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 14 (25.93) | 18.2507 |
| 2000's | 18 (33.33) | 29.6817 |
| 2010's | 19 (35.19) | 24.3611 |
| 2020's | 3 (5.56) | 2.80 |
| Authors | Studies |
|---|---|
| Bowden, CR; Morris, DM; Tuman, RW; Wallace, NH | 1 |
| Demers, LM | 1 |
| Bhatnagar, AS; Dickes, I; Monnet, G; Mueller, P; Trunet, PF; White, G | 1 |
| Ahern, J; Dowsett, M; Iveson, TJ; Smith, IE; Smithers, DA; Trunet, PF | 2 |
| Blankenstein, MA; de Frankrijker, E; Donker, TH; Nortier, HW; Thijssen, JH; van der Wall, E | 1 |
| Brady, C; Demers, LM; Grossberg, H; Harvey, HA; Kambic, KB; Lipton, A; Santen, RJ | 1 |
| Dowsett, M; Fisher, GV; Selen, A; Wyld, PJ; Yates, RA | 1 |
| Choate, JV; Resko, JA | 1 |
| Bisagni, G; Cocconi, G; Fraschini, F; Pfister, C; Scaglione, F; Trunet, PF | 1 |
| Blankenstein, RA; de Jong, PC; Donker, TH; Maitimu-Smeele, I; Nortier, HW; Slee, PH; Thijssen, JH; van de Ven, J | 1 |
| Amoroso, D; Boccardo, F; Brema, F; Cortesi, E; Farris, A; Guida, G; Iacobelli, S; Irtelli, L; Langenaeken, C; Mesiti, M; Mustacchi, G; Nardini, P; Pacini, P | 1 |
| Dowsett, M; Jacobs, S; Johnston, SR; Jones, A; Smith, IE; Trunet, P | 1 |
| Bonneterre, J; Feutrie, ML | 1 |
| Berntsen, H; Geisler, J; Lonning, PE | 1 |
| Donaldson, K; Dowsett, M; Tsuboi, M; Wong, J; Yates, R | 1 |
| Bulun, SE; Sasano, H; Takayama, K; Zeitoun, KM | 1 |
| Criscuoli, M; Lippi, A; Maggi, CA; Mauro, S; Muratori, M; Palma, C | 1 |
| Heshmati, HM; Khosla, S; Melton, LJ; O'Fallon, WM; Riggs, BL; Robins, SP | 1 |
| Anker, G; Dowsett, M; Geisler, J; Haynes, B; Lønning, PE | 1 |
| Dixon, JM; Miller, WR | 1 |
| Dixon, JM; Miller, WR; Sahmoud, T; Stuart, M | 1 |
| Adachi, I; Ikeda, T; Ohashi, Y; Sasaki, Y; Suwa, T; Tabei, T; Takatsuka, Y; Toi, M; Tominaga, T | 1 |
| Bryant, M; Bulun, SE; Hsu, WT; Neely, K; Schultz, RA; Sebastian, S; Shozu, M; Takayama, K | 1 |
| Geisler, J | 1 |
| Bhatnagar, AS; Dixon, JM; Dowsett, M; Haynes, BP; Miller, WR | 1 |
| Hori, H; Kagawa, N; Waterman, MR; Yoshioka, S | 1 |
| Aberdeen, GW; Albrecht, ED; Pepe, GJ | 1 |
| Lykkesfeldt, AE; Sonne-Hansen, K | 1 |
| A'Hern, RP; Cameron, DA; Dixon, JM; Dowsett, M; Folkerd, E; Macaskill, EJ; McHugh, M; Murray, J; Renshaw, L; Young, O | 1 |
| Aas, T; Duong, NK; Ekse, D; Evans, DB; Geisler, J; Helle, H; Lønning, PE; Nordbø, Y | 1 |
| Al-Soud, YA; Bey, E; Frotscher, M; Hartmann, RW; Kruchten, P; Marchais-Oberwinkler, S; Oster, A; Werth, R | 1 |
| Batzler, A; Buzdar, AU; Desta, Z; Flockhart, DA; Goetz, MP; Ingle, JN; Northfelt, DW; Olson, JE; Perez, EA; Robson, ME; Schaid, DJ; Weinshilboum, RM; Weintraub, RA; Williard, CV | 1 |
| Chen, S; Hong, Y; Rashid, R | 1 |
| Horie, T; Shitara, Y; Tanii, H | 1 |
| Bao, T; Blackford, AL; Stearns, V | 1 |
| A'Hern, RP; Dixon, JM; Dowsett, M; Folkerd, EJ; Renshaw, L | 1 |
| Bighin, C; Bisagni, G; Bruzzi, P; Cavazzini, G; Clavarezza, M; Del Mastro, L; Garrone, O; Lastraioli, S; Lunardi, G; Mansutti, M; Marroni, P; Notaro, R; Piccioli, P; Ponzone, R; Porpiglia, M; Puglisi, F; Serra, M | 1 |
| Critchley, HO; Gibson, DA; McInnes, KJ; Saunders, PT | 1 |
| Bighin, C; Bisagni, G; Cirillo, M; Del Mastro, L; Giraudi, S; Gnoni, R; Levaggi, A; Lunardi, G; Mansutti, M; Marenco, D; Picardo, E; Piccioli, P; Ponzone, R; Porpiglia, M; Puglisi, F; Sini, V; Stridi, G; Turazza, M | 1 |
| Dowsett, M; Haynes, BP; Lønning, PE | 1 |
| Bodnár, B; Fiser, G; Kovács, I; Mernyák, E; Ocsovszki, I; Schneider, G; Szabó, J; Wölfling, J; Zupkó, I | 1 |
| Acosta, JI; Alderete, TJ; Bimonte-Nelson, HA; Camp, BW; Demers, LM; Koebele, SV; Mennenga, SE; Mousa, AA; Tsang, CW | 1 |
| Barman, P; Buzdar, AU; Desta, Z; Dudenkov, TT; Flockhart, DA; Goetz, MP; Ingle, JN; Kalari, KR; Northfelt, DW; Perez, EA; Robson, ME; Wang, L; Weinshilboum, RM; Williard, CV | 1 |
| Boros, I; Czégány, D; Kovács, I; Mernyák, E; Minorics, R; Ocsovszki, I; Schneider, G; Sere, P; Sinka, I; Újfaludi, Z; Varga, M; Wölfling, J; Zupkó, I | 1 |
| Bacsa, I; Herman, BE; Kalmár, L; Mernyák, E; Schneider, G; Szabó, J; Szécsi, M; Varga, M; Wölfling, J; Zupkó, I | 1 |
| de la Torre, MC; Frutos, M; Sierra, MA | 1 |
| Bózsity, N; Mernyák, E; Minorics, R; Ocsovszki, I; Schneider, G; Szabó, J; Wang, HC; Wölfling, J; Wu, CC; Zupkó, I | 1 |
| Archer-Chicko, CL; DeMichele, A; Fritz, JS; Kawut, SM; Klinger, JR; Ky, B; Palevsky, HI; Palmisciano, AJ; Patel, M; Pinder, D; Propert, KJ; Smith, KA; Stanczyk, F; Tracy, R; Vaidya, A; Ventetuolo, CE; Whittenhall, ME | 1 |
| Bergamaschi, CC; Coscia, EB; Gerenutti, M; Groppo, FC; Sabha, M | 1 |
| Baj, F; Baravalle, R; Ciaramella, A; Di Nardo, G; Gilardi, G | 1 |
| Cao, H; Feng, H; Fu, J; Li, J; Liu, X; Xue, Q; Zhang, A; Zhang, H | 1 |
| Cai, Z; Leng, P; Li, R; Li, Y; Liu, H; Liu, J; Mahai, G; Xia, W; Xu, S; Zhou, Y | 1 |
| Babbitt, C; Edwards, M; Lacreuse, A; Lam, S; Pereira, M; Ranjan, R | 1 |
4 review(s) available for triazoles and estrone
| Article | Year |
|---|---|
[Aromatase inhibitors].
Topics: Aminoglutethimide; Anastrozole; Androstadienes; Androstenedione; Antineoplastic Agents; Antineoplastic Agents, Hormonal; Aromatase Inhibitors; Breast Neoplasms; Cytochrome P-450 Enzyme Inhibitors; Enzyme Inhibitors; Estrogen Antagonists; Estrone; Female; Humans; Letrozole; Nitriles; Triazoles | 1999 |
Estrogen biosynthesis in endometriosis: molecular basis and clinical relevance.
Topics: Anastrozole; Aromatase; Aromatase Inhibitors; Dinoprostone; Endometriosis; Enzyme Inhibitors; Estrogens; Estrone; Female; Humans; Middle Aged; Mullerian Ducts; Nitriles; Pregnancy; Triazoles | 2000 |
Breast cancer tissue estrogens and their manipulation with aromatase inhibitors and inactivators.
Topics: Anastrozole; Animals; Aromatase Inhibitors; Breast Neoplasms; Enzyme Inhibitors; Estradiol; Estrogens; Estrone; Humans; Nitriles; Postmenopause; Radioimmunoassay; Triazoles | 2003 |
The pharmacology of letrozole.
Topics: Adrenocorticotropic Hormone; Animals; Antineoplastic Agents; Aromatase; Aromatase Inhibitors; Breast Neoplasms; Clinical Trials as Topic; Enzyme Inhibitors; Estradiol; Estrone; Humans; Letrozole; Nitriles; Triazoles | 2003 |
20 trial(s) available for triazoles and estrone
| Article | Year |
|---|---|
Effects of Fadrozole (CGS 16949A) and Letrozole (CGS 20267) on the inhibition of aromatase activity in breast cancer patients.
Topics: Aromatase Inhibitors; Breast Neoplasms; Estradiol; Estrogens; Estrone; Fadrozole; Female; Humans; Letrozole; Middle Aged; Nitriles; Radioimmunoassay; Triazoles | 1994 |
Open dose-finding study of a new potent and selective nonsteroidal aromatase inhibitor, CGS 20 267, in healthy male subjects.
Topics: Administration, Oral; Adult; Aldosterone; Aromatase Inhibitors; Blood Pressure; Dose-Response Relationship, Drug; Estradiol; Estrone; Follicle Stimulating Hormone; Headache; Humans; Hydrocortisone; Letrozole; Luteinizing Hormone; Male; Middle Aged; Nitriles; Testosterone; Triazoles | 1993 |
Phase I study of the oral nonsteroidal aromatase inhibitor CGS 20267 in healthy postmenopausal women.
Topics: 17-alpha-Hydroxyprogesterone; Administration, Oral; Aged; Aldosterone; Androstenedione; Aromatase Inhibitors; Dose-Response Relationship, Drug; Estradiol; Estrone; Female; Follicle Stimulating Hormone; Humans; Hydrocortisone; Hydroxyprogesterones; Letrozole; Luteinizing Hormone; Male; Menopause; Middle Aged; Nitriles; Random Allocation; Testosterone; Thyrotropin; Time Factors; Triazoles | 1993 |
Inhibition of the in vivo conversion of androstenedione to estrone by the aromatase inhibitor vorozole in healthy postmenopausal women.
Topics: Aged; Androstenedione; Aromatase Inhibitors; Carbon Radioisotopes; Double-Blind Method; Estrone; Female; Humans; Postmenopause; Triazoles; Tritium | 1993 |
Phase I study of the oral nonsteroidal aromatase inhibitor CGS 20267 in postmenopausal patients with advanced breast cancer.
Topics: Aromatase Inhibitors; Breast Neoplasms; Estradiol; Estrone; Humans; Letrozole; Microsomes; Middle Aged; Nitriles; Triazoles | 1993 |
The efficacy of CGS 20267 in suppressing estrogen biosynthesis in patients with advanced stage breast cancer.
Topics: Aldosterone; Anti-Inflammatory Agents, Non-Steroidal; Aromatase Inhibitors; Breast Neoplasms; Cosyntropin; Estradiol; Estrogens; Estrone; Female; Humans; Hydrocortisone; Letrozole; Neoplasm Staging; Nitriles; Potassium; Sodium; Time Factors; Triazoles | 1993 |
Arimidex (ZD1033): a selective, potent inhibitor of aromatase in postmenopausal female volunteers.
Topics: Adrenocorticotropic Hormone; Anastrozole; Aromatase Inhibitors; Dose-Response Relationship, Drug; Double-Blind Method; Enzyme Inhibitors; Estradiol; Estrone; Female; Follicle Stimulating Hormone; Hormones; Humans; Hydrocortisone; Luteinizing Hormone; Nitriles; Postmenopause; Steroids; Triazoles | 1996 |
Letrozole, a new oral non-steroidal aromastase inhibitor in treating postmenopausal patients with advanced breast cancer. A pilot study.
Topics: Adult; Aged; Aldosterone; Antineoplastic Agents; Aromatase Inhibitors; Breast Neoplasms; Enzyme Inhibitors; Estradiol; Estrone; Female; Humans; Hydrocortisone; Letrozole; Middle Aged; Nitriles; Pilot Projects; Triazoles | 1996 |
Inhibition of breast cancer tissue aromatase activity and estrogen concentrations by the third-generation aromatase inhibitor vorozole.
Topics: Aged; Antineoplastic Agents; Aromatase; Breast Neoplasms; Estradiol; Estrogens; Estrone; Female; Humans; Middle Aged; Triazoles | 1997 |
Clinical efficacy and endocrine activity of vorozole in postmenopausal breast cancer patients. Results of a multicentric phase II study.
Topics: Aged; Antineoplastic Agents; Aromatase Inhibitors; Breast Neoplasms; Enzyme Inhibitors; Estradiol; Estrone; Female; Humans; Middle Aged; Postmenopause; Triazoles | 1997 |
In vivo measurement of aromatase inhibition by letrozole (CGS 20267) in postmenopausal patients with breast cancer.
Topics: Adult; Aged; Androstenedione; Antineoplastic Agents; Aromatase Inhibitors; Breast Neoplasms; Enzyme Inhibitors; Estradiol; Estrone; Female; Humans; Letrozole; Middle Aged; Neoplasm Proteins; Nitriles; Postmenopause; Triazoles | 1995 |
Role of low levels of endogenous estrogen in regulation of bone resorption in late postmenopausal women.
Topics: Aged; Aromatase Inhibitors; Bone Remodeling; Bone Resorption; Double-Blind Method; Enzyme Inhibitors; Estradiol; Estrogens; Estrone; Female; Humans; Letrozole; Menopause; Middle Aged; Nitriles; Osteoporosis, Postmenopausal; Prospective Studies; Triazoles | 2002 |
Influence of letrozole and anastrozole on total body aromatization and plasma estrogen levels in postmenopausal breast cancer patients evaluated in a randomized, cross-over study.
Topics: Aged; Anastrozole; Antineoplastic Agents; Antineoplastic Agents, Hormonal; Aromatase; Aromatase Inhibitors; Breast Neoplasms; Chromatography, High Pressure Liquid; Cross-Over Studies; Enzyme Inhibitors; Estradiol; Estrogens; Estrone; Female; Humans; Letrozole; Middle Aged; Nitriles; Postmenopause; Radioimmunoassay; Triazoles | 2002 |
Anastrozole ('Arimidex') blocks oestrogen synthesis both peripherally and within the breast in postmenopausal women with large operable breast cancer.
Topics: Aged; Anastrozole; Androstenedione; Antineoplastic Agents, Hormonal; Aromatase; Aromatase Inhibitors; Breast Neoplasms; Double-Blind Method; Enzyme Inhibitors; Estradiol; Estrogen Antagonists; Estrogens; Estrone; Female; Humans; Neoadjuvant Therapy; Neoplasm Staging; Neoplasms, Hormone-Dependent; Nitriles; Postmenopause; Radioimmunoassay; Receptors, Estrogen; Triazoles | 2002 |
Double-blind randomised trial comparing the non-steroidal aromatase inhibitors letrozole and fadrozole in postmenopausal women with advanced breast cancer.
Topics: Administration, Oral; Antineoplastic Agents; Aromatase Inhibitors; Breast Neoplasms; Disease Progression; Double-Blind Method; Enzyme Inhibitors; Estradiol; Estrone; Fadrozole; Female; Humans; Letrozole; Middle Aged; Neoplasm Recurrence, Local; Nitriles; Postmenopause; Receptors, Estrogen; Receptors, Progesterone; Safety; Survival Rate; Triazoles | 2003 |
Letrozole suppresses plasma estradiol and estrone sulphate more completely than anastrozole in postmenopausal women with breast cancer.
Topics: Adult; Aged; Aged, 80 and over; Anastrozole; Antineoplastic Agents; Breast Neoplasms; Chemotherapy, Adjuvant; Cross-Over Studies; Estradiol; Estrone; Female; Humans; Letrozole; Middle Aged; Nitriles; Postmenopause; Radioimmunoassay; Selective Estrogen Receptor Modulators; Tamoxifen; Treatment Outcome; Triazoles | 2008 |
Letrozole is superior to anastrozole in suppressing breast cancer tissue and plasma estrogen levels.
Topics: Aged; Aged, 80 and over; Anastrozole; Antineoplastic Agents; Breast Neoplasms; Chromatography, High Pressure Liquid; Estradiol; Estrogens; Estrone; Female; Humans; Letrozole; Middle Aged; Nitriles; Postmenopause; Radioimmunoassay; Triazoles | 2008 |
Population pharmacokinetic analysis of letrozole in Japanese postmenopausal women.
Topics: Aged; Antineoplastic Agents; Aromatase Inhibitors; Aryl Hydrocarbon Hydroxylases; Asian People; Bilirubin; Body Weight; Creatinine; Cytochrome P-450 CYP2A6; Estradiol; Estrone; Female; Genotype; Humans; Letrozole; Nitriles; Polymorphism, Genetic; Postmenopause; Triazoles | 2011 |
Estrogens and their precursors in postmenopausal women with early breast cancer receiving anastrozole.
Topics: Adult; Aged; Aged, 80 and over; Anastrozole; Androstenedione; Aromatase Inhibitors; Breast Neoplasms; Estradiol; Estrogens; Estrone; Female; Humans; Middle Aged; Nitriles; Postmenopause; Testosterone; Triazoles | 2015 |
Anastrozole in Pulmonary Arterial Hypertension. A Randomized, Double-Blind, Placebo-controlled Trial.
Topics: Anastrozole; Aromatase Inhibitors; Biomarkers; Double-Blind Method; Estradiol; Estrone; Female; Gonadal Steroid Hormones; Humans; Hypertension, Pulmonary; Male; Middle Aged; Nitriles; Progesterone; Steroids; Triazoles | 2017 |
30 other study(ies) available for triazoles and estrone
| Article | Year |
|---|---|
Inhibition of peripheral aromatization in the male cynomolgus monkey by a novel nonsteroidal aromatase inhibitor (R 76713).
Topics: Androstenedione; Animals; Aromatase Inhibitors; Dose-Response Relationship, Drug; Estrone; Injections, Intravenous; Macaca fascicularis; Male; Pharmaceutical Vehicles; Triazoles | 1991 |
Paradoxical effect of an aromatase inhibitor, CGS 20267, on aromatase activity in guinea pig brain.
Topics: Androstenedione; Animals; Aromatase Inhibitors; Binding, Competitive; Brain; Enzyme Inhibitors; Estradiol; Estrone; Guinea Pigs; Kinetics; Letrozole; Male; Microsomes; Nitriles; Orchiectomy; Testosterone; Triazoles | 1996 |
A novel HPLC-RIA method for the simultaneous detection of estrone, estradiol and estrone sulphate levels in breast cancer tissue.
Topics: Anastrozole; Antineoplastic Agents, Hormonal; Breast Neoplasms; Chromatography, High Pressure Liquid; Estradiol; Estrone; Female; Humans; Nitriles; Postmenopause; Radioimmunoassay; Reproducibility of Results; Sensitivity and Specificity; Triazoles | 2000 |
Effects of the aromatase inhibitor anastrozole on serum oestrogens in Japanese and Caucasian women.
Topics: Aged; Anastrozole; Antineoplastic Agents, Hormonal; Aromatase Inhibitors; Asian People; Breast Neoplasms; Enzyme Inhibitors; Estradiol; Estrogens; Estrone; Female; Humans; Japan; Middle Aged; Nitriles; Triazoles; White People | 2000 |
Effect of the aromatase inhibitor, MEN 11066, on growth of two different MCF-7 sublines.
Topics: Androstenedione; Aromatase; Aromatase Inhibitors; Benzofurans; Cell Division; DNA; Dose-Response Relationship, Drug; Enzyme Inhibitors; Estradiol; Estrone; Female; Humans; Microsomes; Placenta; Stereoisomerism; Testosterone; Triazoles; Tritium; Tumor Cells, Cultured | 2000 |
Local endocrine effects of aromatase inhibitors within the breast.
Topics: Anastrozole; Androstadienes; Aromatase; Aromatase Inhibitors; Breast; Breast Neoplasms; Cells, Cultured; Chemotherapy, Adjuvant; Enzyme Inhibitors; Estrogens; Estrone; Female; Fibroblasts; Humans; In Vitro Techniques; Letrozole; Neoplasms, Hormone-Dependent; Nitriles; Triazoles | 2001 |
Estrogen excess associated with novel gain-of-function mutations affecting the aromatase gene.
Topics: Adipose Tissue; Adolescent; Adult; Anastrozole; Androstenedione; Aromatase; Aromatase Inhibitors; Base Sequence; Child; Chromosome Mapping; Chromosomes, Human, Pair 15; Dexamethasone; Enzyme Inhibitors; Estradiol; Estrone; Fibroblasts; Glucocorticoids; Gynecomastia; Humans; Male; Molecular Sequence Data; Mutation; Nitriles; Promoter Regions, Genetic; RNA, Messenger; Transcription, Genetic; Triazoles | 2003 |
Characterization of stable human aromatase expressed in E. coli.
Topics: Amino Acid Sequence; Androstenedione; Arginine; Aromatase; Aromatase Inhibitors; Cell Membrane; Chaperonin 10; Chaperonin 60; Chloramphenicol; Cysteine; Electron Spin Resonance Spectroscopy; Enzyme Stability; Escherichia coli; Estradiol; Estrone; Fadrozole; Gene Expression; Humans; Letrozole; Molecular Sequence Data; Nitriles; Polymorphism, Genetic; Protein Structure, Secondary; Protein Synthesis Inhibitors; Recombinant Proteins; Solubility; Testosterone; Triazoles | 2004 |
Estrogen elicits cortical zone-specific effects on development of the primate fetal adrenal gland.
Topics: Adrenal Cortex; Animals; Dehydroepiandrosterone Sulfate; Estradiol; Estrogens; Estrone; Female; Fetal Development; Letrozole; Nitriles; Organ Size; Papio; Pituitary Gland; Pro-Opiomelanocortin; RNA, Messenger; Triazoles | 2005 |
Endogenous aromatization of testosterone results in growth stimulation of the human MCF-7 breast cancer cell line.
Topics: Androgens; Androstenedione; Aromatase; Aromatase Inhibitors; Blotting, Western; Breast Neoplasms; Cell Line, Tumor; Cell Proliferation; Culture Media; Dose-Response Relationship, Drug; Estrogen Antagonists; Estrogens; Estrone; Female; Humans; Letrozole; Nitriles; Receptors, Estrogen; Testosterone; Triazoles; Tumor Cells, Cultured | 2005 |
The role of the heterocycle in bis(hydroxyphenyl)triazoles for inhibition of 17beta-Hydroxysteroid Dehydrogenase (17beta-HSD) type 1 and type 2.
Topics: Enzyme Inhibitors; Estradiol; Estradiol Dehydrogenases; Estrone; Humans; Triazoles | 2009 |
Variation in anastrozole metabolism and pharmacodynamics in women with early breast cancer.
Topics: Adult; Aged; Aged, 80 and over; Anastrozole; Breast Neoplasms; Cohort Studies; Dose-Response Relationship, Drug; Estrogens; Estrone; Female; Humans; Middle Aged; Nitriles; Postmenopause; Receptors, Estrogen; Testosterone; Triazoles | 2010 |
Binding features of steroidal and nonsteroidal inhibitors.
Topics: Amino Acids; Androgens; Androstadienes; Androstenedione; Aromatase; Aromatase Inhibitors; Binding Sites; Breast Neoplasms; Catalytic Domain; Estrogens; Estrone; Female; Humans; Letrozole; Mutagenesis, Site-Directed; NADPH-Ferrihemoprotein Reductase; Neoplasms, Hormone-Dependent; Nitriles; Protein Conformation; Structure-Activity Relationship; Triazoles | 2011 |
Effect of simvastatin on the pharmacokinetics of anastrozole.
Topics: Aged; Anastrozole; Anticholesteremic Agents; Antineoplastic Agents, Hormonal; Aromatase Inhibitors; Breast Neoplasms; Drug Interactions; Estradiol; Estrone; Female; Humans; Middle Aged; Nitriles; Pilot Projects; Simvastatin; Triazoles | 2012 |
Suppression of plasma estrogen levels by letrozole and anastrozole is related to body mass index in patients with breast cancer.
Topics: Aged; Aged, 80 and over; Anastrozole; Antineoplastic Agents, Hormonal; Aromatase Inhibitors; Body Mass Index; Breast Neoplasms; Estrogens; Estrone; Female; Humans; Letrozole; Middle Aged; Neoplasms, Hormone-Dependent; Nitriles; Postmenopause; Triazoles | 2012 |
Plasma estrone sulfate concentrations and genetic variation at the CYP19A1 locus in postmenopausal women with early breast cancer treated with letrozole.
Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents; Aromatase; Aromatase Inhibitors; Breast Neoplasms; Clinical Trials as Topic; Estrone; Female; Genetic Association Studies; Genotype; Humans; Letrozole; Middle Aged; Nitriles; Polymorphism, Single Nucleotide; Postmenopause; Prospective Studies; Triazoles | 2013 |
Endometrial Intracrinology--generation of an estrogen-dominated microenvironment in the secretory phase of women.
Topics: Anastrozole; Aromatase; Aromatase Inhibitors; Cellular Microenvironment; Decidua; Endometrium; Estradiol; Estrone; Female; Gene Expression Regulation, Enzymologic; Humans; Menstrual Cycle; Multienzyme Complexes; Nitriles; Ovary; Pregnancy; Pregnancy Trimester, First; Primary Cell Culture; Progesterone Reductase; RNA, Messenger; Steroid Isomerases; Stromal Cells; Triazoles | 2013 |
Body mass index and circulating oestrone sulphate in women treated with adjuvant letrozole.
Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents; Aromatase Inhibitors; Body Mass Index; Breast Neoplasms; Chemotherapy, Adjuvant; Estrone; Female; Humans; Letrozole; Middle Aged; Nitriles; Postmenopause; Triazoles | 2014 |
Relationship of body mass index with aromatisation and plasma and tissue oestrogen levels in postmenopausal breast cancer patients treated with aromatase inhibitors.
Topics: Aged; Anastrozole; Androgens; Aromatase; Aromatase Inhibitors; Body Mass Index; Breast Neoplasms; Estradiol; Estrogens; Estrone; Female; Humans; Letrozole; Middle Aged; Nitriles; Outcome Assessment, Health Care; Postmenopause; Triazoles | 2014 |
Synthesis and in vitro antiproliferative evaluation of d-secooxime derivatives of 13β- and 13α-estrone.
Topics: Antineoplastic Agents; Azides; Catalysis; Cell Proliferation; Cycloaddition Reaction; Drug Screening Assays, Antitumor; Estrone; HeLa Cells; Humans; Stereoisomerism; Triazoles | 2014 |
Pharmacological blockade of the aromatase enzyme, but not the androgen receptor, reverses androstenedione-induced cognitive impairments in young surgically menopausal rats.
Topics: Anastrozole; Androgen Antagonists; Androstenedione; Animals; Aromatase Inhibitors; Brain; Cognition Disorders; Estrone; Female; Flutamide; Maze Learning; Menopause; Nitriles; Ovariectomy; Rats, Inbred F344; Receptors, Androgen; Triazoles; Uterus | 2015 |
Synthesis of trans-16-triazolyl-13α-methyl-17-estradiol diastereomers and the effects of structural modifications on their in vitro antiproliferative activities.
Topics: Alkynes; Antineoplastic Agents; Apoptosis; Azides; Caspase 3; Caspase 8; Caspase 9; Cell Adhesion; Cell Line; Cell Line, Tumor; Cell Survival; Cisplatin; Cycloaddition Reaction; Estrone; Fibroblasts; Gene Expression Regulation; Humans; Inhibitory Concentration 50; Quantitative Structure-Activity Relationship; Stereoisomerism; Triazoles | 2015 |
Synthesis and in vitro pharmacological evaluation of N-[(1-benzyl-1,2,3-triazol-4-yl)methyl]-carboxamides on d-secoestrone scaffolds.
Topics: Antineoplastic Agents; Benzyl Compounds; Cell Line, Tumor; Cell Proliferation; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; Enzyme Inhibitors; Estradiol Dehydrogenases; Estrone; HeLa Cells; Humans; MCF-7 Cells; Molecular Structure; Structure-Activity Relationship; Triazoles | 2016 |
Steroid Derived Mesoionic Gold and Silver Mono- and Polymetallic Carbenes.
Topics: Catalysis; Estrone; Ligands; Models, Chemical; Organogold Compounds; Silver; Triazoles | 2015 |
Mechanism of antiproliferative action of a new d-secoestrone-triazole derivative in cervical cancer cells and its effect on cancer cell motility.
Topics: Antineoplastic Agents; Apoptosis; Cell Cycle; Cell Line, Tumor; Cell Movement; Cell Proliferation; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; Estrogen Receptor Modulators; Estrone; Female; Flow Cytometry; HeLa Cells; Human papillomavirus 16; Humans; Necrosis; Neoplasm Invasiveness; Prognosis; Triazoles; Tubulin; Uterine Cervical Neoplasms | 2017 |
Estrone and Estradiol Levels in Breast Cancer Patients Using Anastrozole Are Not Related to Body Mass Index.
Topics: Anastrozole; Antineoplastic Agents, Hormonal; Aromatase Inhibitors; Body Mass Index; Breast Neoplasms; Cohort Studies; Estradiol; Estrone; Female; Humans; Middle Aged; Nitriles; Triazoles | 2017 |
Identification of endocrine disrupting chemicals acting on human aromatase.
Topics: Anastrozole; Aromatase; Aromatase Inhibitors; Benzhydryl Compounds; Biological Assay; Endocrine Disruptors; Enzyme-Linked Immunosorbent Assay; Estrone; Gene Expression; Humans; Ketoconazole; Ligands; NADP; Nicotine; Nitriles; Phenols; Protein Binding; Recombinant Proteins; Resveratrol; Sildenafil Citrate; Small Molecule Libraries; Stilbenes; Triazoles | 2018 |
Estrogenic activity of benzotriazole UV stabilizers evaluated through in vitro assays and computational studies.
Topics: Estrogens; Estrone; Triazoles; Ultraviolet Rays | 2020 |
Associations of benzotriazoles and benzothiazoles with estrogens and androgens among pregnant women: A cohort study with repeated measurements.
Topics: Androgens; Benzothiazoles; Cohort Studies; Cross-Sectional Studies; Dehydroepiandrosterone; Estradiol; Estriol; Estrogens; Estrone; Female; Humans; Male; Pregnancy; Pregnant Women; Prospective Studies; Testosterone; Triazoles | 2022 |
Letrozole treatment alters hippocampal gene expression in common marmosets (Callithrix jacchus).
Topics: Animals; Aromatase Inhibitors; Callithrix; Estrone; Female; Gene Expression; Hippocampus; Letrozole; Male; Nitriles; Triazoles | 2023 |