Page last updated: 2024-08-24

triazoles and efinaconazole

triazoles has been researched along with efinaconazole in 122 studies

Research

Studies (122)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's4 (3.28)29.6817
2010's83 (68.03)24.3611
2020's35 (28.69)2.80

Authors

AuthorsStudies
Arika, T; Tatsumi, Y; Yamaguchi, H; Yokoo, M2
Arika, T; Tatsum, Y; Yamaguchi, H; Yokoo, M1
Kakehi, K; Senda, H; Tatsumi, Y; Yokoo, M1
Elewski, BE; Ieda, C; Olin, JT; Pariser, DM; Pillai, R; Pollak, R; Ramakrishna, T; Rich, P; Senda, H; Smith, K; Watanabe, S1
Fothergill, A; Jo Siu, WJ; Nakamura, T; Pillai, R; Senda, H; Sone, D; Tatsumi, Y1
Bucko, AD; Kawabata, H; Oizumi, N; Olin, JT; Pillai, R; Tschen, EH1
Inui, F; Iwata, A; Kangawa, Y; Nagashima, M; Nishiyama, Y; Pillai, R; Shibanushi, T; Siu, WJ; Tatsumi, Y1
Rich, P2
Jarratt, M; Kodera, N; Pillai, R; Siu, WJ; Smith, K; Yamakawa, E1
Tosti, A1
Dhillon, S; Patel, T1
Lipner, S; Scher, RK1
Kumagai, N; Shibasaki, M; Tamura, K1
Fraser, K1
Jim, SC; Kircik, LH; Routt, ET; Zeichner, JA1
Arakawa, Y; Hosaka, S; Jo Siu, W; Katafuchi-Nagashima, M; Pillai, R; Sugimoto, N; Sugiura, K; Tatsumi, Y1
Gupta, AK; Simpson, FC1
Iwata, A; Katafuchi-Nagashima, M; Kumagai, N; Pillai, R; Sugiura, K; Tatsumi, Y; Watanabe, Y1
Elewski, BE; Gupta, AK; Ieda, C; Kang, R; Kawabata, H; Olin, JT; Pillai, R; Sugarman, JL; Watanabe, S1
Calvarese, B; Glynn, M; Jo, W; Minowa, K; Mutter, L; Nejishima, H; Pillai, R; Sanada, H; Senda, H1
Pollak, RA1
Glynn, M; Jo, W; Matsuuchi, H; Minowa, K; Mutter, L; Nejishima, H; Okamura, H; Pillai, R; Sanada, H1
Joseph, WS; Vlahovic, TC1
Kawabata, H; Kodera, N; Pillai, R; Sakamoto, M; Sugimoto, N; Tatsumi, Y; Yamakawa, E1
Elewski, BE; Olin, JT; Pillai, R; Pollak, RA1
Kircik, LH1
Bhatia, N; Friedlander, SF; Gupta, AK; Kircik, L; Rosen, T; Stein Gold, L; Zirwas, MJ1
Bhatt, V; Pillai, R1
Lipner, SR; Scher, RK3
Canavan, T; Cantrell, W; Elewski, B1
Tatsumi, Y1
Hanafusa, T; Hirohata, A; Ikegami, R; Mabuchi-Kiyohara, E1
Arakawa, K; Hidaka, H; Honkura, Y; Ikeda, R; Katori, Y; Kawase, T; Nomura, K; Oshima, H1
Bhatia, N1
Gupta, AK; Pillai, R1
Jellinek, NJ; Korotzer, A1
Hussar, DA1
Caldwell, B; Markinson, B1
Rosen, T2
Cohen, J; Joyce, C; Mikailov, A; Mostaghimi, A1
Chanda, S; Coronado, D; Merchant, T; Vlahovic, TC; Zane, LT1
Cernea, M; Gupta, AK1
Dorval, E; Grace, Y; Machin, JD; Poulakos, M1
Hossin, B; Murdan, S; Rizi, K1
Koga, H; Maeda, J; Makimura, K; Nanjoh, Y; Toga, T; Tsuboi, R1
Bhatia, N; Caldwell, B; Elewski, BE; Gupta, AK; Kircik, LH; Pariser, DM; Rosen, T; Tosti, A1
Rosen, T; Stein Gold, LF3
Chanda, S; Coronado, D; Del Rosso, J; Zane, LT1
Lagrew, JP1
Elewski, BE1
Koski, R; Maki, K; Nybo, SE; Saunders, J1
Hiruma, M; Ihn, H; Kano, R; Matsumoto, T; Noguchi, H2
Gupta, AK; Korotzer, A1
Gupta, AK; Studholme, C1
Hirayanagi, K; Imai, A; Iwanaga, T; Kubota, N; Miyamae, A; Shibuya, K; Shimamura, T1
Kawada, A; Oiso, N; Tatebayashi, M1
Furuya, K; Hoshina, D; Yamaguchi, Y1
Cook-Bolden, FE; Lin, T1
Ahmadi, B; Alshahni, MM; Ansari, S; Badali, H; Makimura, K; Mirhendi, H; Rezaei-Matehkolaei, A; Shokoohi, GR; Vaezi, A1
Adigun, CG; Gellings Lowe, N; Hall, SB; Joseph, WS; Rich, P; Vlahovic, TC; Zane, LT1
Hasuko, M; Hirano, H; Inagaki, K; Motoba, K; Shiomi, R; Takahashi, Y; Tsuboi, R1
Ilie, C; Pollak, RA1
Cantrell, W; Elewski, BE; Lin, T1
Imazu, Y; Suzuki, J; Uchida, E; Yamaura, K; Yoneta, Y1
Hayashi, N; Imazu, Y; Suzuki, J; Uchida, E; Yamaura, K; Yoneta, Y1
Baltazar, LM; Costa-Orlandi, CB; Friedman, AJ; Friedman, JM; Mendes-Giannini, MJS; Mordorski, B; Nosanchuk, JD1
Asao, K; Fukushima, S; Hirose, M; Hiruma, M; Ihn, H; Matsumoto, T; Noguchi, H1
Bonhert, K; Dorizas, A; Sadick, NS1
Fukushima, S; Hirose, M; Hiruma, M; Ihn, H; Matsumoto, T; Noguchi, H; Yaguchi, T1
Karasawa, T; Kumagai, N; Oriez, R; Shibasaki, M1
Hur, MS; Jung, WH; Lee, YW; Park, M1
Ko, D; Lipner, SR1
Abe, M; Fujii, M; Fukuzawa, M; Hata, Y; Hattori, N; Iozumi, K; Ito, Y; Kasai, H; Katayama, I; Kato, F; Kato, I; Kiryu, H; Kodama, K; Kusuhara, M; Maruyama, R; Mayama, J; Mochizuki, T; Muramoto, F; Nakasu, I; Nishimoto, S; Nomiyama, T; Oh-I, T; Omi, T; Onoduka, T; Sato, T; Sei, Y; Seishima, M; Shimoyama, H; Shindo, M; Sugiura, K; Takahashi, H; Takeda, O; Takenaka, M; Tomizawa, K; Tsuboi, R; Uesugi, T; Watanabe, S; Yamamoto, O; Yamanaka, K; Yasuda, H1
Burgalassi, S; Celandroni, F; Ghelardi, E; Mazzantini, D; Monti, D; Tampucci, S; Vecchione, A1
Kawai, M1
Lin, K; Lipner, SR1
Koo, KT; Lee, BC; Na, J; Pangeni, R; Park, JW1
Harada, K; Inagaki, K; Kampirapap, K; Koga, H; Maeda, J; Makimura, K; Nanjoh, Y; Neki, D; Reangchainam, S; Tsuboi, R; Yuasa, K1
Kuwano, Y; Sei, Y; Shimoyama, H1
Ahmad Nasrollahi, S; Azizzadeh-Roodpishi, S; Dowlatiy, Y; Ehsani, AH; Fattahi, A; Firooz, A; Ghasemi, Z; Malakooti, S; Naeimifar, A; Samadi, A1
Lipner, SR; Wang, Y1
Abastabar, M; Ahangarkani, F; Badali, H; Fakhim, H; Haghani, I; Ilkit, M; Javidnia, J; Meis, JF; Taheri Rizi, Z1
Hamedani, E; Harkless, L; Navarrete, R; Seun, J; Shofler, D; Thamby, R1
Geizhals, S; Lipner, SR; Wu, AG1
Gupta, AK; Piguet, V; Shear, NH; Venkataraman, M1
Eichenfield, LF; Elewski, B; Guenin, E; Gupta, AK; Pillai, R; Rosen, T; Sugarman, JL; Vlahovic, TC1
Abe, N; Anzawa, K; Fukumoto, T; Komatsu-Fujii, T; Nonoyama, S; Ogawa, M; Ookura, T; Tanabe, H1
Fujimoto, K; Mayumi, N; Otsuka, Y; Saeki, H; Yamaguchi, H1
Eichenfield, LF; Elewski, B; Guenin, E; Gupta, AK; Pillai, R; Rosen, T; Stein Gold, L; Sugarman, JL; Vlahovic, TC1
Geizhals, S; Lipner, SR1
Cooper, EA; Gupta, AK1
Hirakawa, S; Inagaki, K; Nagai, H; Nakamura, A1
Agrawal, V; Mishra, S; Patel, M; Patel, R; Thanki, K1
Choi, YS; Ho, MJ; Jang, SW; Kang, MJ; Kim, EA; Kim, JS; Park, DW; Park, JS1
Ansari, S; Goodarzi, S; Javidnia, J; Maryami, F; Mirhendi, H; Rasekh-Jahromi, A; Rezaei-Matehkolaei, A; Romeo, O; Shokoohi, G1
Aoi, J; Fukushima, S; Kashiwada-Nakamura, K; Kubo, M; Makino, K; Noguchi, H1
Gupta, AK; Vlahovic, TC1
Asharani, IV; Govindarajan, S1
Abe, M; Fujii, M; Fukuzawa, M; Hattori, N; Iozumi, K; Ito, Y; Kasai, H; Kato, F; Kato, I; Kiryu, H; Kodama, K; Kusuhara, M; Maruyama, R; Mayama, J; Mochizuki, T; Muramoto, F; Nakasu, I; Nishimoto, S; Oh-I, T; Omi, T; Onoduka, T; Seishima, M; Shimoyama, H; Shindo, M; Sugiura, K; Takahashi, H; Takeda, O; Takenaka, M; Tateishi, Y; Tomizawa, K; Tsuboi, R; Uesugi, T; Watanabe, S; Watanabe-Okada, E; Yamamoto, O; Yamanaka, K; Yasuda, H1
Anbalagan, N; Guenin, EP; Gupta, AK; Venkataraman, M1
Abramovits, W; Guenin, EP; Gupta, AK; Venkataraman, M1
Bila, NM; Costa-Orlandi, CB; Friedman, AJ; Friedman, JM; Martinez, LR; Mendes-Giannini, MJS; Nosanchuk, JD1
Murota, H; Nishimoto, K; Takenaka, M1
Garoufalis, MG1
Guillot, J; Rezaei-Matehkolaei, A; Shamsizadeh, F; Shariat Nabavi, M; Taghipour, S; Zarei Mahmoudabadi, A1
Gupta, AK; Talukder, M1
Masumoto, A; Matsuda, Y; Nakamura, S; Sugiura, K; Takagi, M; Tatsumi, Y1
Hiruma, M; Kano, R; Kimura, U; Kubo, M; Matsumoto, T; Noguchi, H; Tanaka, M; Yaguchi, T; Yamada, T1
Iijima, S; Murayama, K; Takayama, N1
Abastabar, M; Aghili, SR; Badali, H; Faeli, L; Haghani, I; Hedayati, MT; Javan-Nikkhah, M; Javidnia, J; Kachuei, R; Katiraee, F; Khodavaisy, S; M S Al Hatmi, A; Mohammadi, R; Najafzadeh, MJ; Nazeri, M; Nosratabadi, M; Salimi, M; Shokohi, T; Zarrinfar, H1
Fukushima, S; Higuchi, S; Hiruma, M; Kano, R; Kashiwada-Nakamura, K; Kubo, M; Matsumoto, T; Noguchi, H; Satoh, T; Yaguchi, T1
Chen, FE; Ju, Z; Kaliaperumal, K; Li, M; Li, Z; Xu, S1

Reviews

19 review(s) available for triazoles and efinaconazole

ArticleYear
What is new in fungal pharmacotherapeutics?
    Journal of drugs in dermatology : JDD, 2014, Volume: 13, Issue:4

    Topics: Allylamine; Antifungal Agents; Boron Compounds; Bridged Bicyclo Compounds, Heterocyclic; Education, Medical, Continuing; Humans; Imidazoles; Itraconazole; Onychomycosis; Tinea Pedis; Triazoles

2014
The efficacy and safety of efinaconazole 10% solution for treatment of mild to moderate onychomycosis: a pooled analysis of two phase 3 randomized trials.
    Journal of drugs in dermatology : JDD, 2014, Volume: 13, Issue:7

    Topics: Administration, Topical; Aged; Antifungal Agents; Clinical Trials, Phase III as Topic; Female; Foot Dermatoses; Humans; Male; Middle Aged; Onychomycosis; Pharmaceutical Solutions; Randomized Controlled Trials as Topic; Severity of Illness Index; Treatment Outcome; Triazoles

2014
Efinaconazole topical solution, 10%: the development of a new topical treatment for toenail onychomycosis.
    Journal of the American Podiatric Medical Association, 2014, Volume: 104, Issue:6

    Topics: Administration, Topical; Antifungal Agents; Foot Dermatoses; Humans; Onychomycosis; Triazoles

2014
Enhancing transungual delivery and spreading of efinaconazole under the nail plate through a unique formulation approach.
    Journal of drugs in dermatology : JDD, 2014, Volume: 13, Issue:12

    Topics: Administration, Topical; Antifungal Agents; Chemistry, Pharmaceutical; Drug Delivery Systems; Humans; Nails; Onychomycosis; Permeability; Triazoles

2014
Onychomycosis: epidemiology, diagnosis, and treatment in a changing landscape.
    Journal of drugs in dermatology : JDD, 2015, Volume: 14, Issue:3

    Topics: Anti-Infective Agents, Local; Antifungal Agents; Boron Compounds; Bridged Bicyclo Compounds, Heterocyclic; Humans; Onychomycosis; Pharmaceutical Solutions; Treatment Outcome; Triazoles

2015
[Pharmacological characteristics and clinical results of efinaconazole (Clenafin® Topical Solution 10%), a novel anti-onychomycosis drug].
    Nihon yakurigaku zasshi. Folia pharmacologica Japonica, 2015, Volume: 145, Issue:5

    Topics: Animals; Antifungal Agents; Clinical Trials as Topic; Drug Resistance; Humans; Onychomycosis; Pharmaceutical Solutions; Triazoles

2015
Efinaconazole 10% topical solution for the topical treatment of onychomycosis of the toenail.
    Expert review of clinical pharmacology, 2015, Volume: 8, Issue:6

    Topics: Administration, Topical; Animals; Antifungal Agents; Foot Dermatoses; Humans; Onychomycosis; Triazoles

2015
New drugs 2015, part 3.
    Nursing, 2015, Volume: 45, Issue:10

    Topics: Acids, Carbocyclic; Benzoxazines; Boron Compounds; Bridged Bicyclo Compounds, Heterocyclic; Cephalosporins; Cyclopentanes; Drug Approval; Drug Combinations; Drug Therapy; Glucagon-Like Peptides; Guanidines; Humans; Imidazoles; Immunoglobulin Fc Fragments; Interferon-beta; Isoquinolines; Penicillanic Acid; Polyethylene Glycols; Pyridines; Quinuclidines; Recombinant Fusion Proteins; Tazobactam; Triazoles; United States; United States Food and Drug Administration

2015
Evaluation of gender as a clinically relevant outcome variable in the treatment of onychomycosis with efinaconazole topical solution 10.
    Cutis, 2015, Volume: 96, Issue:3

    Topics: Administration, Topical; Adolescent; Adult; Aged; Antifungal Agents; Double-Blind Method; Female; Foot Dermatoses; Humans; Male; Middle Aged; Onychomycosis; Prospective Studies; Randomized Controlled Trials as Topic; Sex Factors; Treatment Outcome; Triazoles; Young Adult

2015
Efinaconazole and Tavaborole.
    Journal of pharmacy practice, 2017, Volume: 30, Issue:2

    Topics: Administration, Topical; Animals; Antifungal Agents; Boron Compounds; Bridged Bicyclo Compounds, Heterocyclic; Clinical Trials as Topic; Foot Dermatoses; Humans; Microbial Sensitivity Tests; Onychomycosis; Triazoles

2017
Antifungal agents for onychomycosis: new treatment strategies to improve safety.
    Dermatology online journal, 2016, Mar-16, Volume: 22, Issue:3

    Topics: Administration, Oral; Administration, Topical; Antifungal Agents; Boron Compounds; Bridged Bicyclo Compounds, Heterocyclic; Chemical and Drug Induced Liver Injury; Ciclopirox; Cytochrome P-450 CYP2D6 Inhibitors; Cytochrome P-450 CYP3A Inhibitors; Drug Interactions; Humans; Itraconazole; Naphthalenes; Onychomycosis; Pyridones; Terbinafine; Triazoles

2016
Tavaborole, Efinaconazole, and Luliconazole: Three New Antimycotic Agents for the Treatment of Dermatophytic Fungi.
    Journal of pharmacy practice, 2017, Volume: 30, Issue:6

    Topics: Administration, Topical; Animals; Antifungal Agents; Arthrodermataceae; Boron Compounds; Bridged Bicyclo Compounds, Heterocyclic; Dermatomycoses; Humans; Imidazoles; Microbial Sensitivity Tests; Randomized Controlled Trials as Topic; Treatment Outcome; Triazoles

2017
Ungual hyalohyphomycosis caused by Fusarium proliferatum in an immunocompetent patient.
    The Journal of dermatology, 2017, Volume: 44, Issue:1

    Topics: Administration, Topical; Aged; Antifungal Agents; Female; Foot Dermatoses; Fusariosis; Fusarium; Humans; Hyphae; Naphthalenes; Onychomycosis; Terbinafine; Triazoles

2017
Onychomycosis: Treatment and prevention of recurrence.
    Journal of the American Academy of Dermatology, 2019, Volume: 80, Issue:4

    Topics: Antifungal Agents; Boron Compounds; Bridged Bicyclo Compounds, Heterocyclic; Ciclopirox; Fluconazole; Humans; Itraconazole; Laser Therapy; Nanoparticles; Onychomycosis; Photochemotherapy; Plasma Gases; Prognosis; Pulse Therapy, Drug; Risk Factors; Secondary Prevention; Severity of Illness Index; Terbinafine; Triazoles

2019
Characteristics and Efficacy of Two Topical Therapeutic Agents for Onychomycosis.
    Medical mycology journal, 2019, Volume: 60, Issue:3

    Topics: Administration, Topical; Antifungal Agents; Drug Resistance, Fungal; Humans; Imidazoles; Keratins; Nails; Onychomycosis; Solutions; Triazoles; Trichophyton

2019
A Timeline of Onychomycosis Therapy and Future Directions.
    Skinmed, 2020, Volume: 18, Issue:6

    Topics: Administration, Topical; Antifungal Agents; Humans; Itraconazole; Nail Diseases; Onychomycosis; Terbinafine; Triazoles

2020
Efinaconazole topical solution (10%) for the treatment of onychomycosis in adult and pediatric patients.
    Expert review of anti-infective therapy, 2022, Volume: 20, Issue:1

    Topics: Administration, Topical; Adult; Antifungal Agents; Child; Humans; Onychomycosis; Pediatrics; Triazoles

2022
One size does not fit all: the need for individualized treatment based on factors that may affect the therapeutic outcome of efinaconazole 10% solution for the treatment of toenail onychomycosis.
    International journal of dermatology, 2021, Volume: 60, Issue:10

    Topics: Administration, Topical; Antifungal Agents; Foot Dermatoses; Humans; Nails; Onychomycosis; Quality of Life; Treatment Outcome; Triazoles

2021
Efinaconazole in Onychomycosis.
    American journal of clinical dermatology, 2022, Volume: 23, Issue:2

    Topics: Administration, Topical; Adult; Antifungal Agents; Child; Female; Humans; Onychomycosis; Triazoles

2022

Trials

24 trial(s) available for triazoles and efinaconazole

ArticleYear
Efinaconazole 10% solution in the treatment of toenail onychomycosis: Two phase III multicenter, randomized, double-blind studies.
    Journal of the American Academy of Dermatology, 2013, Volume: 68, Issue:4

    Topics: Adolescent; Adult; Aged; Antifungal Agents; Double-Blind Method; Female; Foot Dermatoses; Humans; Male; Middle Aged; Onychomycosis; Triazoles; Young Adult

2013
Efinaconazole solution in the treatment of toenail onychomycosis: a phase 2, multicenter, randomized, double-blind study.
    Journal of drugs in dermatology : JDD, 2013, Volume: 12, Issue:2

    Topics: Administration, Topical; Adult; Antifungal Agents; Chemistry, Pharmaceutical; Double-Blind Method; Female; Humans; Male; Middle Aged; Nails; Onychomycosis; Pharmaceutical Solutions; Research Design; Treatment Outcome; Triazoles; Young Adult

2013
Safety and pharmacokinetics of efinaconazole 10% solution in healthy volunteers and patients with severe onychomycosis.
    Journal of drugs in dermatology : JDD, 2013, Volume: 12, Issue:9

    Topics: Administration, Topical; Adult; Aged; Antifungal Agents; Area Under Curve; Dose-Response Relationship, Drug; Drug Interactions; Ethnicity; Female; Half-Life; Humans; Male; Middle Aged; Nails; Onychomycosis; Pharmaceutical Solutions; Triazoles; Young Adult

2013
Efinaconazole topical, 10% for the treatment of toenail onychomycosis in patients with diabetes.
    Journal of drugs in dermatology : JDD, 2014, Volume: 13, Issue:10

    Topics: Administration, Topical; Adult; Aged; Antifungal Agents; Diabetes Mellitus; Double-Blind Method; Female; Foot Dermatoses; Humans; Male; Middle Aged; Onychomycosis; Treatment Outcome; Triazoles

2014
Transungual delivery of efinaconazole: its deposition in the nail of onychomycosis patients and in vitro fungicidal activity in human nails.
    Journal of drugs in dermatology : JDD, 2014, Volume: 13, Issue:11

    Topics: Administration, Topical; Adult; Aged; Antifungal Agents; Drug Delivery Systems; Female; Follow-Up Studies; Foot Dermatoses; Humans; In Vitro Techniques; Male; Microbial Sensitivity Tests; Middle Aged; Nails; Onychomycosis; Permeability; Triazoles; Trichophyton

2014
Access of efinaconazole topical solution, 10%, to the infection site by spreading through the subungual space.
    Journal of drugs in dermatology : JDD, 2014, Volume: 13, Issue:11

    Topics: Administration, Topical; Antifungal Agents; Female; Foot Dermatoses; Humans; Male; Middle Aged; Nails; Onychomycosis; Permeability; Treatment Outcome; Triazoles

2014
Efinaconazole topical solution, 10%: the benefits of treating onychomycosis early.
    Journal of drugs in dermatology : JDD, 2015, Volume: 14, Issue:1

    Topics: Administration, Topical; Adult; Antifungal Agents; Disease Progression; Double-Blind Method; Female; Foot Dermatoses; Humans; Male; Middle Aged; Onychomycosis; Prospective Studies; Time Factors; Treatment Outcome; Triazoles

2015
Managing Assessments and Expectations: Patient Responses Following Therapy With Efinaconazole Topical Solution, 10%.
    Journal of drugs in dermatology : JDD, 2015, Volume: 14, Issue:7

    Topics: Administration, Topical; Adolescent; Adult; Aged; Antifungal Agents; Double-Blind Method; Female; Humans; Male; Middle Aged; Nails; Onychomycosis; Patient Satisfaction; Severity of Illness Index; Treatment Outcome; Triazoles; Young Adult

2015
The Presence of an Air Gap Between the Nail Plate and Nail Bed in Onychomycosis Patients: Treatment Implications for Topical Therapy.
    Journal of drugs in dermatology : JDD, 2015, Volume: 14, Issue:8

    Topics: Administration, Cutaneous; Adult; Aged; Air; Antifungal Agents; Female; Fluorescein; Foot Dermatoses; Humans; Male; Middle Aged; Nails; Onychomycosis; Pharmaceutical Vehicles; Severity of Illness Index; Triazoles

2015
Prognostic Factors for Complete Cure Following Treatment of Mild and Moderate Toenail Onychomycosis With Efinaconazole Topical Solution 10.
    Journal of drugs in dermatology : JDD, 2015, Volume: 14, Issue:8

    Topics: Administration, Cutaneous; Adolescent; Adult; Aged; Antifungal Agents; Double-Blind Method; Female; Foot Dermatoses; Humans; Male; Middle Aged; Onychomycosis; Prognosis; Severity of Illness Index; Treatment Outcome; Triazoles; Young Adult

2015
Efinaconazole Topical Solution, 10% Efficacy in Patients with Onychomycosis and Coexisting Tinea Pedis.
    Journal of the American Podiatric Medical Association, 2015, Volume: 105, Issue:5

    Topics: Administration, Topical; Adolescent; Adult; Aged; Antifungal Agents; Double-Blind Method; Female; Follow-Up Studies; Humans; Male; Middle Aged; Onychomycosis; Tinea Pedis; Treatment Outcome; Triazoles; Young Adult

2015
Cost-effectiveness of Confirmatory Testing Before Treatment of Onychomycosis.
    JAMA dermatology, 2016, Volume: 152, Issue:3

    Topics: Administration, Oral; Administration, Topical; Algorithms; Cost Savings; Cost-Benefit Analysis; Decision Support Techniques; Decision Trees; Health Care Costs; Humans; Hydroxides; Naphthalenes; Onychomycosis; Periodic Acid-Schiff Reaction; Potassium Compounds; Potentially Inappropriate Medication List; Terbinafine; Triazoles

2016
A financial perspective on the topical treatment of onychomycosis.
    Journal of the American Academy of Dermatology, 2016, Volume: 75, Issue:1

    Topics: Administration, Topical; Antifungal Agents; Boron Compounds; Bridged Bicyclo Compounds, Heterocyclic; Cost-Benefit Analysis; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Costs; Female; Follow-Up Studies; Foot Dermatoses; Humans; Male; Onychomycosis; Risk Assessment; Treatment Outcome; Triazoles

2016
Topical Treatment of Onychomycosis and Clinically Meaningful Outcomes.
    Journal of drugs in dermatology : JDD, 2016, Oct-01, Volume: 15, Issue:10

    Topics: Administration, Topical; Adolescent; Adult; Aged; Antifungal Agents; Double-Blind Method; Female; Follow-Up Studies; Foot Dermatoses; Humans; Male; Middle Aged; Onychomycosis; Treatment Outcome; Triazoles; Young Adult

2016
Long-Term Follow-up of Onychomycosis Patients Treated With Efinaconazole
    Journal of drugs in dermatology : JDD, 2017, 12-01, Volume: 16, Issue:12

    Topics: Administration, Cutaneous; Adolescent; Adult; Aged; Aged, 80 and over; Antifungal Agents; Boron Compounds; Bridged Bicyclo Compounds, Heterocyclic; Drug Administration Schedule; Female; Follow-Up Studies; Humans; Male; Middle Aged; Onychomycosis; Treatment Outcome; Triazoles; Young Adult

2017
Is Severity of Disease a Prognostic Factor for Cure Following Treatment of Onychomycosis?
    Journal of drugs in dermatology : JDD, 2018, Feb-01, Volume: 17, Issue:2

    Topics: Administration, Topical; Adolescent; Adult; Aged; Antifungal Agents; Double-Blind Method; Female; Foot Dermatoses; Humans; Male; Middle Aged; Onychomycosis; Prognosis; Severity of Illness Index; Treatment Outcome; Triazoles; Young Adult

2018
Efficacy of combination therapy with efinaconazole 10% solution and 1064 nm Nd:YAG laser for treatment of toenail onychomycosis.
    Journal of cosmetic and laser therapy : official publication of the European Society for Laser Dermatology, 2019, Volume: 21, Issue:3

    Topics: Administration, Topical; Adult; Aged; Antifungal Agents; Combined Modality Therapy; Female; Follow-Up Studies; Foot Dermatoses; Humans; Laser Therapy; Lasers, Solid-State; Male; Middle Aged; Onychomycosis; Patient Satisfaction; Photography; Statistics, Nonparametric; Treatment Outcome; Triazoles

2019
Efficacy of long-term treatment with efinaconazole 10% solution in patients with onychomycosis, including severe cases: A multicenter, single-arm study.
    The Journal of dermatology, 2019, Volume: 46, Issue:8

    Topics: Administration, Topical; Aged; Antifungal Agents; Drug-Related Side Effects and Adverse Reactions; Female; Foot Dermatoses; Humans; Incidence; Long-Term Care; Male; Middle Aged; Onychomycosis; Quality of Life; Severity of Illness Index; Time Factors; Treatment Outcome; Triazoles

2019
Efinaconazole topical solution 10%: Formulation and efficacy assessment in the treatment of toenail onychomycosis.
    Mycoses, 2020, Volume: 63, Issue:5

    Topics: Administration, Topical; Adolescent; Adult; Aged; Antifungal Agents; Female; Foot; Humans; Male; Middle Aged; Nail Diseases; Nails; Onychomycosis; Pilot Projects; Triazoles; Young Adult

2020
Efficacy and Safety of Efinaconazole 10% Solution in the Treatment of Onychomycosis in Diabetic Patients.
    Clinics in podiatric medicine and surgery, 2020, Volume: 37, Issue:2

    Topics: Administration, Topical; Adult; Aged; Antifungal Agents; Blood Glucose; Diabetes Complications; Female; Foot Dermatoses; Humans; Male; Middle Aged; Onychomycosis; Treatment Outcome; Triazoles

2020
Labeled use of efinaconazole topical solution 10% in treating onychomycosis in children and a review of the management of pediatric onychomycosis.
    Dermatologic therapy, 2020, Volume: 33, Issue:4

    Topics: Administration, Topical; Adolescent; Antifungal Agents; Child; Foot Dermatoses; Humans; Multicenter Studies as Topic; Onychomycosis; Triazoles

2020
Efinaconazole 10% topical solution for the treatment of onychomycosis in pediatric patients: Open-label phase 4 study.
    Journal of the American Academy of Dermatology, 2021, Volume: 84, Issue:4

    Topics: Administration, Cutaneous; Adolescent; Antifungal Agents; Child; Female; Foot Dermatoses; Humans; Male; Onychomycosis; Solutions; Treatment Outcome; Triazoles

2021
Safety, Pharmacokinetics, and Efficacy of Efinaconazole 10% Topical Solution for Onychomycosis Treatment in Pediatric Patients.
    Journal of drugs in dermatology : JDD, 2020, Sep-01, Volume: 19, Issue:9

    Topics: Administration, Topical; Adolescent; Antifungal Agents; Area Under Curve; Child; Female; Follow-Up Studies; Foot Dermatoses; Fungi; Humans; Male; Onychomycosis; Severity of Illness Index; Solutions; Treatment Outcome; Triazoles

2020
Long-term Efficacy and Safety of Once-daily Efinaconazole 10% Topical Solution (Jublia) for Dermatophyte Toenail Onychomycosis: An Interim Analysis.
    Skin therapy letter, 2021, Volume: 26, Issue:1

    Topics: Administration, Cutaneous; Aged; Antifungal Agents; Drug Administration Schedule; Female; Foot Dermatoses; Humans; Male; Middle Aged; Onychomycosis; Treatment Outcome; Triazoles

2021

Other Studies

79 other study(ies) available for triazoles and efinaconazole

ArticleYear
In vitro antifungal activity of KP-103, a novel triazole derivative, and its therapeutic efficacy against experimental plantar tinea pedis and cutaneous candidiasis in guinea pigs.
    Antimicrobial agents and chemotherapy, 2001, Volume: 45, Issue:5

    Topics: Animals; Antifungal Agents; Blood Proteins; Candida; Candidiasis, Cutaneous; Culture Media; Disease Models, Animal; Guinea Pigs; Hair; Microbial Sensitivity Tests; Tinea Pedis; Treatment Outcome; Triazoles; Trichophyton

2001
KP-103, a novel triazole derivative, is effective in preventing relapse and successfully treating experimental interdigital tinea pedis and tinea corporis in guinea pigs.
    Microbiology and immunology, 2002, Volume: 46, Issue:7

    Topics: Animals; Antibiotic Prophylaxis; Antifungal Agents; Aspergillus flavus; Disease Models, Animal; Drug Evaluation, Preclinical; Guinea Pigs; Keratins; Male; Microbial Sensitivity Tests; Secondary Prevention; Tinea; Tinea Pedis; Toes; Treatment Outcome; Triazoles; Trichophyton

2002
In vivo fungicidal effect of KP-103 in a guinea pig model of interdigital tinea pedis determined by using a new method for removing the antimycotic carryover effect.
    Microbiology and immunology, 2002, Volume: 46, Issue:7

    Topics: Animals; Antifungal Agents; Colony Count, Microbial; Culture Media; Drug Evaluation, Preclinical; Guinea Pigs; Heterocyclic Compounds; Imidazoles; Male; Microbial Sensitivity Tests; Models, Animal; Time Factors; Tinea Pedis; Treatment Outcome; Triazoles; Trichophyton

2002
Therapeutic efficacy of topically applied KP-103 against experimental tinea unguium in guinea pigs in comparison with amorolfine and terbinafine.
    Antimicrobial agents and chemotherapy, 2002, Volume: 46, Issue:12

    Topics: Administration, Oral; Administration, Topical; Animals; Antifungal Agents; Guinea Pigs; Male; Microbial Sensitivity Tests; Morpholines; Naphthalenes; Onychomycosis; Terbinafine; Tinea Pedis; Triazoles; Trichophyton

2002
Comparison of in vitro antifungal activities of efinaconazole and currently available antifungal agents against a variety of pathogenic fungi associated with onychomycosis.
    Antimicrobial agents and chemotherapy, 2013, Volume: 57, Issue:4

    Topics: Antifungal Agents; Aspergillus; Candida; Cryptococcus; Itraconazole; Microbial Sensitivity Tests; Morpholines; Naphthalenes; Onychomycosis; Pseudallescheria; Scopulariopsis; Terbinafine; Triazoles; Trichophyton; Trichosporon

2013
Mechanism of action of efinaconazole, a novel triazole antifungal agent.
    Antimicrobial agents and chemotherapy, 2013, Volume: 57, Issue:5

    Topics: 14-alpha Demethylase Inhibitors; Antifungal Agents; Candida albicans; Dose-Response Relationship, Drug; Ergosterol; Hyphae; Microbial Sensitivity Tests; Microscopy, Electron, Scanning; Sterols; Triazoles; Trichophyton

2013
Topical treatment of onychomycosis with efinaconazole solution 10%.
    Cutis, 2013, Volume: 91, Issue:6

    Topics: Adult; Antifungal Agents; Foot Dermatoses; Humans; Male; Onychomycosis; Triazoles; Trichophyton

2013
Efinaconazole solution 10%: topical antifungal therapy for toenail onychomycosis.
    Cutis, 2013, Volume: 92, Issue:4

    Topics: Administration, Topical; Antifungal Agents; Foot Dermatoses; Humans; Onychomycosis; Recurrence; Triazoles

2013
Efinaconazole: first global approval.
    Drugs, 2013, Volume: 73, Issue:17

    Topics: Administration, Topical; Animals; Antifungal Agents; Drug Approval; Humans; Onychomycosis; Pharmaceutical Solutions; Triazoles

2013
Onychomycosis: current and future therapies.
    Cutis, 2014, Volume: 93, Issue:2

    Topics: Antifungal Agents; Boron Compounds; Bridged Bicyclo Compounds, Heterocyclic; Ciclopirox; Debridement; Foot Dermatoses; Hand Dermatoses; Humans; Laser Therapy; Morpholines; Naphthalenes; Onychomycosis; Pyridones; Terbinafine; Triazoles

2014
An enantioselective synthesis of the key intermediate for triazole antifungal agents; application to the catalytic asymmetric synthesis of efinaconazole (Jublia).
    The Journal of organic chemistry, 2014, Apr-04, Volume: 79, Issue:7

    Topics: Antifungal Agents; Catalysis; Molecular Structure; Stereoisomerism; Triazoles

2014
72nd annual meeting of the American Academy of Dermatology.
    American journal of clinical dermatology, 2014, Volume: 15, Issue:2

    Topics: Antifungal Agents; Attention Deficit Disorder with Hyperactivity; Boron Compounds; Botulinum Toxins, Type A; Bridged Bicyclo Compounds, Heterocyclic; Brimonidine Tartrate; Depression; Dermatitis, Atopic; Food Hypersensitivity; Humans; Immunologic Factors; Ivermectin; Phosphodiesterase Inhibitors; Phototherapy; Piperidines; Protein Kinase Inhibitors; Pyrimidines; Pyrroles; Quinoxalines; Skin Diseases; Societies, Medical; Thalidomide; Triazoles; United States

2014
The low keratin affinity of efinaconazole contributes to its nail penetration and fungicidal activity in topical onychomycosis treatment.
    Antimicrobial agents and chemotherapy, 2014, Volume: 58, Issue:7

    Topics: Administration, Topical; Animals; Antifungal Agents; Guinea Pigs; Humans; In Vitro Techniques; Keratins; Microbial Sensitivity Tests; Nails; Onychomycosis; Tinea; Triazoles; Trichophyton

2014
Efinaconazole (Jublia) for the treatment of onychomycosis.
    Expert review of anti-infective therapy, 2014, Volume: 12, Issue:7

    Topics: 14-alpha Demethylase Inhibitors; Administration, Topical; Clinical Trials as Topic; Ergosterol; Humans; Microbial Sensitivity Tests; Onychomycosis; Triazoles

2014
In vitro and in vivo assessment of dermatophyte acquired resistance to efinaconazole, a novel triazole antifungal.
    Antimicrobial agents and chemotherapy, 2014, Volume: 58, Issue:8

    Topics: Administration, Topical; Animals; Antifungal Agents; Colony Count, Microbial; Drug Resistance, Fungal; Guinea Pigs; Microbial Sensitivity Tests; Onychomycosis; Triazoles; Trichophyton

2014
News drugs and dosage forms.
    American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists, 2014, Jul-15, Volume: 71, Issue:14

    Topics: Anti-HIV Agents; Antifungal Agents; Atazanavir Sulfate; Drug Combinations; Humans; Ketorolac; Oligopeptides; Phenylephrine; Pyridines; Testosterone; Triazoles

2014
Nonclinical safety assessment of Efinaconazole Solution (10%) for onychomycosis treatment.
    Regulatory toxicology and pharmacology : RTP, 2014, Volume: 70, Issue:1

    Topics: Administration, Cutaneous; Administration, Topical; Animals; Antifungal Agents; Dose-Response Relationship, Drug; Female; Injections, Subcutaneous; Male; Mice; Mice, Inbred ICR; No-Observed-Adverse-Effect Level; Onychomycosis; Pharmaceutical Solutions; Rats; Rats, Sprague-Dawley; Skin; Swine; Swine, Miniature; Time Factors; Triazoles

2014
Efinaconazole topical solution (Jublia) for onychomycosis.
    The Medical letter on drugs and therapeutics, 2014, Sep-15, Volume: 56, Issue:1451

    Topics: Administration, Topical; Antifungal Agents; Drug Approval; Humans; Onychomycosis; Triazoles; United States; United States Food and Drug Administration

2014
Efinaconazole: Developmental and reproductive toxicity potential of a novel antifungal azole.
    Reproductive toxicology (Elmsford, N.Y.), 2015, Volume: 52

    Topics: Animals; Animals, Newborn; Antifungal Agents; Dose-Response Relationship, Drug; Embryonic Development; Estrous Cycle; Female; Fertility; Fetal Death; Male; Rabbits; Rats; Reproduction; Triazoles

2015
Efinaconazole topical solution, 10%: formulation development program of a new topical treatment of toenail onychomycosis.
    Journal of pharmaceutical sciences, 2015, Volume: 104, Issue:7

    Topics: Administration, Topical; Antifungal Agents; Chemistry, Pharmaceutical; Drug Delivery Systems; Foot Dermatoses; Humans; Nail Diseases; Nails; Onychomycosis; Permeability; Pharmaceutical Solutions; Solubility; Triazoles

2015
Management of onychomycosis and co-existing tinea pedis.
    Journal of drugs in dermatology : JDD, 2015, Volume: 14, Issue:5

    Topics: Administration, Topical; Antifungal Agents; Clinical Trials as Topic; Humans; Onychomycosis; Severity of Illness Index; Tinea Pedis; Triazoles

2015
Report of a case of a dermatophytoma successfully treated with topical efinaconazole 10% solution.
    Journal of drugs in dermatology : JDD, 2015, Volume: 14, Issue:5

    Topics: Administration, Topical; Aged; Antifungal Agents; Foot Dermatoses; Humans; Male; Naphthalenes; Onychomycosis; Terbinafine; Tinea; Treatment Outcome; Triazoles

2015
Contact dermatitis caused by efinaconazole solution for treatment of onychomycosis.
    Contact dermatitis, 2015, Volume: 73, Issue:3

    Topics: Administration, Topical; Antifungal Agents; Dermatitis, Allergic Contact; Humans; Male; Middle Aged; Onychomycosis; Patch Tests; Solutions; Triazoles

2015
Effect of intratympanic application of efinaconazole 10 % solution in the guinea pig.
    European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery, 2016, Volume: 273, Issue:5

    Topics: Animals; Antifungal Agents; Ear, Middle; Evoked Potentials, Auditory, Brain Stem; Gentamicins; Guinea Pigs; Hair Cells, Auditory; Hearing Loss; Injection, Intratympanic; Male; Solutions; Triazoles

2016
Evaluation of the Appearance of Nail Polish Following Daily Treatment of Ex Vivo Human Fingernails With Topical Solutions of Tavaborole or Efinaconazole.
    Journal of drugs in dermatology : JDD, 2016, Volume: 15, Issue:1

    Topics: Antifungal Agents; Boron Compounds; Bridged Bicyclo Compounds, Heterocyclic; Humans; Nails; Onychomycosis; Triazoles

2016
How effective is efinaconazole in the management of onychomycosis?
    Expert opinion on pharmacotherapy, 2016, Volume: 17, Issue:4

    Topics: Antifungal Agents; Disease Management; Humans; Nails; Onychomycosis; Pharmaceutical Solutions; Triazoles

2016
Application of Hansen Solubility Parameters to predict drug-nail interactions, which can assist the design of nail medicines.
    European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V, 2016, Volume: 102

    Topics: Adolescent; Adult; Antifungal Agents; Ciclopirox; Drug Interactions; Female; Humans; Keratins; Male; Middle Aged; Morpholines; Nail Diseases; Nails; Naphthalenes; Onychomycosis; Pharmaceutical Preparations; Pyridones; Solubility; Terbinafine; Triazoles; Young Adult

2016
[In vitro Antifungal Activity of Luliconazole against Trichophyton spp].
    Medical mycology journal, 2016, Volume: 57, Issue:1

    Topics: Allylamine; Antifungal Agents; Drug Resistance, Fungal; Imidazoles; Microbial Sensitivity Tests; Naphthalenes; Pyridines; Terbinafine; Thiocarbamates; Triazoles; Trichophyton

2016
Onychomycosis: Strategies to Minimize Recurrence.
    Journal of drugs in dermatology : JDD, 2016, Volume: 15, Issue:3

    Topics: Administration, Topical; Antifungal Agents; Comorbidity; Diabetes Mellitus; Drug Administration Schedule; Humans; Itraconazole; Morpholines; Naphthalenes; Onychomycosis; Prevalence; Recurrence; Terbinafine; Tinea Pedis; Triazoles

2016
Antifungal Drugs for Onychomycosis: Efficacy, Safety, and Mechanisms of Action.
    Seminars in cutaneous medicine and surgery, 2016, Volume: 35, Issue:3 Suppl 3

    Topics: Administration, Cutaneous; Administration, Oral; Antifungal Agents; Boron Compounds; Bridged Bicyclo Compounds, Heterocyclic; Ciclopirox; Clinical Trials as Topic; Clinical Trials, Phase III as Topic; Fluconazole; Foot Dermatoses; Humans; Itraconazole; Naphthalenes; Onychomycosis; Pyridones; Terbinafine; Treatment Outcome; Triazoles; United States

2016
Introduction.
    Seminars in cutaneous medicine and surgery, 2016, Volume: 35, Issue:3 Suppl 3

    Topics: Administration, Cutaneous; Antifungal Agents; Boron Compounds; Bridged Bicyclo Compounds, Heterocyclic; Ciclopirox; Foot Dermatoses; Humans; Naphthalenes; Onychomycosis; Pyridones; Terbinafine; Treatment Outcome; Triazoles

2016
Using Topical Antifungal Medications: Instructions for patients.
    Seminars in cutaneous medicine and surgery, 2016, Volume: 35, Issue:3 Suppl 3

    Topics: Administration, Cutaneous; Antifungal Agents; Boron Compounds; Bridged Bicyclo Compounds, Heterocyclic; Ciclopirox; Drug Administration Schedule; Foot Dermatoses; Humans; Onychomycosis; Pyridones; Triazoles

2016
Response to "A financial perspective on the topical treatment of onychomycosis".
    Journal of the American Academy of Dermatology, 2016, Volume: 75, Issue:1

    Topics: Administration, Topical; Antifungal Agents; Boron Compounds; Bridged Bicyclo Compounds, Heterocyclic; Cost-Benefit Analysis; Drug Costs; Female; Foot Dermatoses; Humans; Male; Onychomycosis; Sensitivity and Specificity; Severity of Illness Index; Triazoles

2016
Ungual aspergillosis successfully treated with topical efinaconazole.
    The Journal of dermatology, 2017, Volume: 44, Issue:7

    Topics: Administration, Topical; Aged; Antifungal Agents; Aspergillosis; Female; Humans; Onychomycosis; Triazoles

2017
Tinea and Onychomycosis.
    Seminars in cutaneous medicine and surgery, 2016, Volume: 35, Issue:6 Suppl

    Topics: Administration, Cutaneous; Antifungal Agents; Humans; Imidazoles; Onychomycosis; Recurrence; Tinea; Tinea Pedis; Triazoles

2016
Update on Efinaconazole 10% Topical Solution for the Treatment of Onychomycosis.
    Skin therapy letter, 2016, Volume: 21, Issue:6

    Topics: Administration, Topical; Antifungal Agents; Clinical Trials, Phase III as Topic; Humans; Onychomycosis; Solutions; Triazoles

2016
Comparison of Characteristics of Two Topical Therapeutic Agents for Onychomycosis.
    Medical mycology journal, 2016, Volume: 57, Issue:4

    Topics: Administration, Topical; Antifungal Agents; Dose-Response Relationship, Drug; Drug Discovery; Drug Resistance, Fungal; Humans; Imidazoles; In Vitro Techniques; Nails; Onychomycosis; Solutions; Triazoles; Trichophyton

2016
Allergic contact dermatitis caused by efinaconazole: positive patch test reactions up to 0.1% pet.
    Contact dermatitis, 2017, Volume: 76, Issue:1

    Topics: Administration, Topical; Aged; Antifungal Agents; Dermatitis, Allergic Contact; Foot Dermatoses; Humans; Male; Onychomycosis; Patch Tests; Triazoles

2017
Onychomadesis caused by efinaconazole.
    Contact dermatitis, 2017, Volume: 76, Issue:1

    Topics: Administration, Topical; Aged; Antifungal Agents; Dermatitis, Allergic Contact; Foot Dermatoses; Humans; Male; Nail Diseases; Onychomycosis; Patch Tests; Triazoles

2017
Efinaconazole solution 10% for treatment of toenail onychomycosis in Latino patients.
    Cutis, 2017, Volume: 99, Issue:4

    Topics: Administration, Topical; Antifungal Agents; Female; Foot Dermatoses; Hispanic or Latino; Humans; Male; Middle Aged; Onychomycosis; Randomized Controlled Trials as Topic; Treatment Outcome; Triazoles; United States

2017
    Antimicrobial agents and chemotherapy, 2017, Volume: 61, Issue:11

    Topics: Adult; Antifungal Agents; Ascomycota; Child, Preschool; Drug Resistance, Fungal; Female; Humans; Imidazoles; Male; Microbial Sensitivity Tests; Middle Aged; Mycoses; Triazoles; Yeasts; Young Adult

2017
Clinical trial designs for topical antifungal treatments of onychomycosis and implications on clinical practice.
    Cutis, 2017, Volume: 100, Issue:4

    Topics: Administration, Cutaneous; Antifungal Agents; Boron Compounds; Bridged Bicyclo Compounds, Heterocyclic; Ciclopirox; Clinical Trials, Phase III as Topic; Drug Approval; Humans; Onychomycosis; Pyridones; Research Design; Treatment Outcome; Triazoles; United States

2017
[Affinity of Luliconazole for Human Nail Derived Keratin].
    Medical mycology journal, 2017, Volume: 58, Issue:4

    Topics: Humans; Imidazoles; Keratins; Nails; Onychomycosis; Triazoles

2017
[Current Status of Onychomycosis Topical Therapy Conducted at Home].
    Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan, 2018, Volume: 138, Issue:5

    Topics: Antifungal Agents; Caregivers; Home Care Services; Humans; Infectious Disease Transmission, Professional-to-Patient; Onychomycosis; Triazoles

2018
[Role of Pharmacists in Topical Therapy for Onychomycosis in the Home-care Setting].
    Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan, 2018, Volume: 138, Issue:5

    Topics: Administration, Topical; Antifungal Agents; Community Pharmacy Services; Home Care Services; Humans; Japan; Onychomycosis; Patient Compliance; Pharmacists; Prevalence; Professional Role; Quality of Life; Triazoles

2018
Nitric Oxide Releasing Nanoparticles as a Strategy to Improve Current Onychomycosis Treatments.
    Journal of drugs in dermatology : JDD, 2018, Jul-01, Volume: 17, Issue:7

    Topics: Administration, Topical; Animals; Antifungal Agents; Disease Models, Animal; Drug Carriers; Drug Liberation; Drug Synergism; Drug Therapy, Combination; Humans; Mice; Microbial Sensitivity Tests; Nanoparticles; Naphthalenes; Nitric Oxide; Onychomycosis; Permeability; Prescription Fees; Terbinafine; Treatment Outcome; Triazoles; Trichophyton

2018
Topical efinaconazole: A promising therapeutic medication for tinea unguium.
    The Journal of dermatology, 2018, Volume: 45, Issue:10

    Topics: Administration, Topical; Aged; Aged, 80 and over; Antifungal Agents; Female; Foot Dermatoses; Hand Dermatoses; Humans; Male; Middle Aged; Onychomycosis; Photography; Treatment Outcome; Triazoles

2018
Onychomycosis caused by Aspergillus subramanianii.
    The Journal of dermatology, 2018, Volume: 45, Issue:11

    Topics: Administration, Cutaneous; Administration, Oral; Adult; Antifungal Agents; Aspergillosis; Aspergillus; Female; Foot Dermatoses; Humans; Hyphae; Japan; Microscopy; Onychomycosis; Terbinafine; Triazoles; Young Adult

2018
anti-Selective Catalytic Asymmetric Nitroaldol Reaction of α-Keto Esters: Intriguing Solvent Effect, Flow Reaction, and Synthesis of Active Pharmaceutical Ingredients.
    Journal of the American Chemical Society, 2018, 09-26, Volume: 140, Issue:38

    Topics: Alcohols; Catalysis; Esters; Furans; Ketones; Neodymium; Nitro Compounds; Quinazolines; Sodium; Solvents; Stereoisomerism; Triazoles

2018
Evaluation of drug susceptibility test for Efinaconazole compared with conventional antifungal agents.
    Mycoses, 2019, Volume: 62, Issue:3

    Topics: Antifungal Agents; Candida albicans; Humans; Microbial Sensitivity Tests; Onychomycosis; Tinea; Triazoles; Trichophyton

2019
Optimizing topical therapy for onychomycosis: the importance of patient education.
    Cutis, 2018, Volume: 102, Issue:6

    Topics: Administration, Topical; Antifungal Agents; Boron Compounds; Bridged Bicyclo Compounds, Heterocyclic; Ciclopirox; Humans; Medication Adherence; Onychomycosis; Patient Education as Topic; Triazoles

2018
Ciclopirox and Efinaconazole Transungual Permeation, Antifungal Activity, and Proficiency To Induce Resistance in Trichophyton rubrum.
    Antimicrobial agents and chemotherapy, 2019, Volume: 63, Issue:10

    Topics: Animals; Antifungal Agents; Biological Transport; Cattle; Ciclopirox; Drug Resistance, Fungal; Hoof and Claw; Humans; Keratins; Microbial Sensitivity Tests; Microtomy; Models, Biological; Mutation; Nails; Permeability; Protein Binding; Tinea; Triazoles; Trichophyton

2019
Modeling of usage and estimation of cost for efinaconazole 10% topical solution in the treatment of onychomycosis.
    Journal of the American Academy of Dermatology, 2020, Volume: 83, Issue:1

    Topics: Administration, Topical; Antifungal Agents; Drug Costs; Foot Dermatoses; Healthy Volunteers; Humans; Nails; Onychomycosis; Solutions; Triazoles; United States

2020
Preparation and
    Drug delivery, 2019, Volume: 26, Issue:1

    Topics: Administration, Topical; Animals; Antifungal Agents; Disease Models, Animal; Guinea Pigs; Humans; In Vitro Techniques; Male; Membranes, Artificial; Nails; Onychomycosis; Permeability; Skin; Skin Absorption; Tinea; Triazoles; Trichophyton

2019
In vitro antifungal activity of luliconazole against nondermatophytic moulds.
    Medical mycology, 2020, Jul-01, Volume: 58, Issue:5

    Topics: Amphotericin B; Antifungal Agents; Clotrimazole; Fluconazole; Fungi; Humans; Imidazoles; Itraconazole; Ketoconazole; Miconazole; Microbial Sensitivity Tests; Morpholines; Sequence Analysis, DNA; Terbinafine; Triazoles; Voriconazole

2020
Retrospective Survey of Treatment Outcomes of Efinaconazole 10% Solution and Luliconazole 5% Solution for Onychomycosis in Our Facility.
    Medical mycology journal, 2019, Volume: 60, Issue:4

    Topics: Administration, Topical; Adult; Aged; Female; Humans; Imidazoles; Male; Middle Aged; Onychomycosis; Retrospective Studies; Solutions; Treatment Outcome; Triazoles

2019
Retrospective analysis of adverse events with topical onychomycosis medications reported to the United States Food and Drug Administration.
    Archives of dermatological research, 2020, Volume: 312, Issue:8

    Topics: Administration, Topical; Adverse Drug Reaction Reporting Systems; Antifungal Agents; Boron Compounds; Bridged Bicyclo Compounds, Heterocyclic; Ciclopirox; Erythema; Humans; Nails; Onychomycosis; Pigmentation; Retrospective Studies; Solutions; Treatment Failure; Triazoles; United States; United States Food and Drug Administration

2020
Antifungal Activity of a Novel Triazole, Efinaconazole and Nine Comparators against 354 Molecularly Identified Aspergillus Isolates.
    Mycopathologia, 2020, Volume: 185, Issue:2

    Topics: Antifungal Agents; Aspergillosis; Aspergillus; Microbial Sensitivity Tests; Triazoles

2020
Retrospective study of factors affecting medication adherence in patients prescribed efinaconazole 10% solution for onychomycosis.
    Journal of the American Academy of Dermatology, 2021, Volume: 84, Issue:1

    Topics: Administration, Topical; Age Factors; Antifungal Agents; Drug Prescriptions; Humans; Medication Adherence; Onychomycosis; Prescription Fees; Retrospective Studies; Triazoles

2021
Usefulness of topical efinaconazole for infantile tinea capitis due to Microsporum canis diagnosed with Wood's light.
    The Journal of dermatology, 2020, Volume: 47, Issue:11

    Topics: Humans; Microsporum; Tinea Capitis; Triazoles

2020
Contact Dermatitis Caused by Efinaconazole and Luliconazole.
    Journal of Nippon Medical School = Nippon Ika Daigaku zasshi, 2021, Jun-30, Volume: 88, Issue:3

    Topics: Administration, Topical; Aged; Antifungal Agents; Dermatitis, Contact; Epitopes; Foot Dermatoses; Humans; Imidazoles; Male; Patch Tests; Triazoles

2021
A comparative study between two antifungal agents, Luliconazole and Efinaconazole, of their preventive effects in a Trichophyton-infected guinea pig onychomycosis model.
    Medical mycology, 2021, Mar-04, Volume: 59, Issue:3

    Topics: Administration, Topical; Animals; Antifungal Agents; Disease Models, Animal; Guinea Pigs; Imidazoles; Male; Specific Pathogen-Free Organisms; Tinea; Triazoles; Trichophyton

2021
Design and evaluation of microemulsion-based efinaconazole formulations for targeted treatment of onychomycosis through transungual route: Ex vivo and nail clipping studies.
    Colloids and surfaces. B, Biointerfaces, 2021, Volume: 201

    Topics: Antifungal Agents; Arthrodermataceae; Emulsions; Humans; Nails; Onychomycosis; Triazoles

2021
Effect of Penetration Enhancers on Toenail Delivery of Efinaconazole from Hydroalcoholic Preparations.
    Molecules (Basel, Switzerland), 2021, Mar-16, Volume: 26, Issue:6

    Topics: Administration, Topical; Animals; Antifungal Agents; Cattle; Diffusion; Drug Carriers; Drug Delivery Systems; Hoof and Claw; Onychomycosis; Permeability; Propylene Glycol; Triazoles

2021
Molecular identification and antifungal susceptibility profiles of Candida dubliniensis and Candida africana isolated from vulvovaginal candidiasis: A single-centre experience in Iran.
    Mycoses, 2021, Volume: 64, Issue:7

    Topics: Adult; Antifungal Agents; Candida; Candidiasis, Vulvovaginal; DNA, Fungal; Female; Fungal Proteins; Humans; Imidazoles; Iran; Membrane Glycoproteins; Microbial Sensitivity Tests; Middle Aged; Prevalence; Triazoles

2021
Topical efinaconazole: A sequential combination therapy with oral terbinafine for refractory tinea unguium.
    The Journal of dermatology, 2021, Volume: 48, Issue:9

    Topics: Administration, Topical; Antifungal Agents; Humans; Onychomycosis; Terbinafine; Triazoles

2021
Development and Validation of a LC-MS/MS Method for the Profiling of Impurities Formed during Stress Study of Antifungal Agent-Efinaconazole.
    Journal of chromatographic science, 2022, Apr-28, Volume: 60, Issue:4

    Topics: Antifungal Agents; Chromatography, High Pressure Liquid; Chromatography, Liquid; Drug Stability; Hydrolysis; Oxidation-Reduction; Photolysis; Reproducibility of Results; Tandem Mass Spectrometry; Triazoles

2022
Clinical effectiveness of efinaconazole 10% solution for treatment of onychomycosis with longitudinal spikes.
    The Journal of dermatology, 2021, Volume: 48, Issue:10

    Topics: Administration, Topical; Antifungal Agents; Humans; Onychomycosis; Treatment Outcome; Triazoles

2021
JUBLIA (Efinaconazole 10% Solution) in the Treatment of Pediatric Onychomycosis.
    Skinmed, 2021, Volume: 19, Issue:3

    Topics: Administration, Topical; Adolescent; Adult; Aged; Antifungal Agents; Child; Foot Dermatoses; Humans; Onychomycosis; Terbinafine; Triazoles

2021
Nitric Oxide-Releasing Nanoparticles Are Similar to Efinaconazole in Their Capacity to Eradicate
    Frontiers in cellular and infection microbiology, 2021, Volume: 11

    Topics: Antifungal Agents; Arthrodermataceae; Biofilms; Microbial Sensitivity Tests; Nanoparticles; Nitric Oxide; Triazoles; Trichophyton

2021
Chronological evaluation of treatment effect for tinea unguium with efinaconazole: Possibility of an early estimation of treatment effects.
    The Journal of dermatology, 2021, Volume: 48, Issue:12

    Topics: Administration, Topical; Antifungal Agents; Humans; Onychomycosis; Triazoles

2021
Total Dystrophic Onychomycosis Successfully Treated with Efinaconazole Topical Solution in Times of Coronavirus Disease of 2019: A Case Study.
    Journal of the American Podiatric Medical Association, 2022, Apr-27, Volume: 112, Issue:2

    Topics: Administration, Topical; Adult; Antifungal Agents; Coronavirus; Female; Foot Dermatoses; Humans; Onychomycosis; Treatment Outcome; Triazoles

2022
In vitro activities of 8 antifungal agents against geophilic dermatophyte isolates.
    Mycoses, 2022, Volume: 65, Issue:2

    Topics: Antifungal Agents; Arthrodermataceae; Imidazoles; Itraconazole; Microbial Sensitivity Tests; Terbinafine; Triazoles

2022
A novel method for predicting the efficacy of topical drugs on onychomycosis: A comparison of efinaconazole and luliconazole.
    Journal de mycologie medicale, 2022, Volume: 32, Issue:3

    Topics: Administration, Topical; Antifungal Agents; Humans; Imidazoles; Nails; Onychomycosis; Triazoles

2022
Effective Response of Dermatophytoma Caused by Terbinafine-Resistant Trichophyton interdigitale Solely to Topical Efinaconazole.
    Mycopathologia, 2022, Volume: 187, Issue:4

    Topics: Antifungal Agents; Arthrodermataceae; Drug Resistance, Fungal; Microbial Sensitivity Tests; Terbinafine; Triazoles; Trichophyton

2022
[ANALYSIS OF PATCH TEST RESULTS FOR INDIVIDUAL INGREDIENTS IN PATIENTS WITH ALLERGIC CONTACT DERMATITIS CAUSED BY 10% EFINACONAZOLE NAIL SOLUTION].
    Arerugi = [Allergy], 2022, Volume: 71, Issue:4

    Topics: Allergens; Dermatitis, Allergic Contact; Ethanol; Humans; Patch Tests; Petrolatum; Triazoles

2022
In vitro antifungal susceptibility profile of Iranian Fusarium isolates: Emphasising on the potent inhibitory effect of efinaconazole compared to other drugs.
    Mycoses, 2023, Volume: 66, Issue:3

    Topics: Antifungal Agents; Fusariosis; Fusarium; Humans; Iran; Microbial Sensitivity Tests; Triazoles

2023
Onychomycosis Caused by Talaromyces muroii Successfully Treated with Efinaconazole.
    Mycopathologia, 2023, Volume: 188, Issue:5

    Topics: Administration, Topical; Antifungal Agents; Foot Dermatoses; Humans; Onychomycosis; Talaromyces; Triazoles

2023
A Chemo-Enzymatic Approach for Preparing Efinaconazole with High Optical Yield.
    The Journal of organic chemistry, 2023, 10-20, Volume: 88, Issue:20

    Topics: Benzoin; Ketones; Thiamine Pyrophosphate; Triazoles

2023