triazoles has been researched along with dora-22 in 9 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 7 (77.78) | 24.3611 |
| 2020's | 2 (22.22) | 2.80 |
| Authors | Studies |
|---|---|
| Ball, RG; Bednar, RA; Bogusky, MJ; Breslin, MJ; Cabalu, TD; Coleman, PJ; Cox, CD; Cui, D; Doran, SM; Fox, SV; Garson, SL; Gotter, AL; Harrell, CM; Hartman, GD; Lemaire, W; McGaughey, GB; Prueksaritanont, T; Reiss, DR; Renger, JJ; Schreier, JD; Stellabott, J; Stevens, J; Tannenbaum, PL; Whitman, DB; Winrow, CJ; Young, SD | 1 |
| Binns, J; Bowlby, MR; Brunner, J; Cannon, CE; Coleman, PJ; Eddins, DM; Fox, SV; Garson, SL; Gotter, AL; Hodgson, R; Kuduk, SD; Mcdonald, TP; Renger, JJ; Savitz, AT; Stevens, J; Tannenbaum, PL; Tye, SJ; Uslaner, JM; Wang, X; Winrow, CJ; Yao, L | 1 |
| Crow, JM | 1 |
| Bowlby, MR; Brunner, JI; Coleman, PJ; Fox, SV; Garson, SL; Gotter, AL; Hargreaves, R; Hodgson, R; Kuduk, SD; McDonald, TP; Renger, JJ; Savitz, AT; Tannenbaum, PL; Tye, SJ; Uslaner, JM; Winrow, CJ; Yao, L | 1 |
| Coleman, PJ; Fox, SV; Garson, SL; Gotter, AL; Kuduk, SD; McDonald, T; Munden, RL; Renger, JJ; Stevens, J; Tannenbaum, PL; Tye, SJ; Uslaner, JM; Winrow, CJ; Yao, L | 1 |
| Coleman, PJ; Fox, SV; Gotter, AL; Hargreaves, R; Kuduk, SD; Renger, JJ; Savitz, AT; Stevens, J; Tannenbaum, PL; Tye, SJ; Uslaner, JM; Winrow, CJ | 1 |
| Coleman, PJ; Fox, SV; Gotter, AL; Hodgson, R; Ramirez, AD; Renger, JJ; Roecker, AJ; Smith, SM; Uslaner, JM; Winrow, CJ; Yao, L | 1 |
| Gamble, MC; Katsuki, F; McCoy, JG; McKenna, JT; Strecker, RE | 2 |
9 other study(ies) available for triazoles and dora-22
| Article | Year |
|---|---|
Discovery of [(2R,5R)-5-{[(5-fluoropyridin-2-yl)oxy]methyl}-2-methylpiperidin-1-yl][5-methyl-2-(pyrimidin-2-yl)phenyl]methanone (MK-6096): a dual orexin receptor antagonist with potent sleep-promoting properties.
Topics: Animals; Brain; Dogs; Drug Discovery; Humans; Hypnotics and Sedatives; Magnetic Resonance Spectroscopy; Models, Molecular; Orexin Receptors; Piperidines; Protein Binding; Pyridines; Rats; Receptors, G-Protein-Coupled; Receptors, Neuropeptide; Sleep; Sleep Initiation and Maintenance Disorders; Stereoisomerism; Structure-Activity Relationship; Triazoles; Wakefulness | 2012 |
Orexin receptor antagonists differ from standard sleep drugs by promoting sleep at doses that do not disrupt cognition.
Topics: Administration, Oral; Animals; Attention; Azabicyclo Compounds; Choice Behavior; Cognition; Cytoskeletal Proteins; Diazepam; Eszopiclone; gamma-Aminobutyric Acid; Hippocampus; Hypnotics and Sedatives; Macaca mulatta; Male; Memory, Short-Term; Nerve Tissue Proteins; Orexin Receptors; Piperazines; Piperidines; Pyridines; Rats; Rats, Sprague-Dawley; Rats, Wistar; Receptors, G-Protein-Coupled; Receptors, Neuropeptide; Recognition, Psychology; Sleep; Task Performance and Analysis; Time Factors; Triazoles; Zolpidem | 2013 |
Insomnia: chasing the dream.
Topics: Animals; Arousal; Azabicyclo Compounds; Azepines; Benzodiazepines; Cognitive Behavioral Therapy; Doxepin; Dreams; Histamine Agonists; Histamine Antagonists; Humans; Hypnotics and Sedatives; Hypothalamus; Orexin Receptors; Piperazines; Piperidines; Receptors, G-Protein-Coupled; Receptors, GABA; Receptors, Histamine H3; Receptors, Neuropeptide; Sleep Initiation and Maintenance Disorders; Triazoles | 2013 |
Quantitative electroencephalography within sleep/wake states differentiates GABAA modulators eszopiclone and zolpidem from dual orexin receptor antagonists in rats.
Topics: Animals; Azabicyclo Compounds; Brain; Electroencephalography; Eszopiclone; GABA-A Receptor Agonists; Male; Orexin Receptor Antagonists; Piperazines; Piperidines; Pyridines; Rats; Rats, Sprague-Dawley; Sleep Stages; Triazoles; Zolpidem | 2013 |
Differential sleep-promoting effects of dual orexin receptor antagonists and GABAA receptor modulators.
Topics: Animals; Azabicyclo Compounds; Azepines; Benzimidazoles; Brain; Cross-Over Studies; Dogs; Electroencephalography; Eszopiclone; GABA Modulators; Hypnotics and Sedatives; Intracellular Signaling Peptides and Proteins; Macaca mulatta; Male; Mice, Inbred C57BL; Neurons; Neuropeptides; Orexin Receptor Antagonists; Orexins; Piperazines; Piperidines; Rats, Sprague-Dawley; Rats, Transgenic; Sleep; Sleep Deprivation; Sleep Stages; Species Specificity; Triazoles; Wakefulness | 2014 |
Inhibition of Orexin Signaling Promotes Sleep Yet Preserves Salient Arousability in Monkeys.
Topics: Animals; Arousal; Conditioning, Classical; Cross-Over Studies; Diazepam; Eszopiclone; GABA Agents; Hypnotics and Sedatives; Macaca mulatta; Male; Orexin Receptor Antagonists; Orexins; Piperidines; Polysomnography; Signal Transduction; Sleep; Sleep Stages; Triazoles; Wakefulness | 2016 |
The dual orexin receptor antagonist, DORA-22, lowers histamine levels in the lateral hypothalamus and prefrontal cortex without lowering hippocampal acetylcholine.
Topics: Acetylcholine; Animals; gamma-Aminobutyric Acid; Hippocampus; Histamine; Hypothalamic Area, Lateral; Male; Orexin Receptor Antagonists; Piperidines; Prefrontal Cortex; Rats; Sleep; Sleep Initiation and Maintenance Disorders; Triazoles; Wakefulness | 2017 |
The dual orexinergic receptor antagonist DORA-22 improves the sleep disruption and memory impairment produced by a rodent insomnia model.
Topics: Animals; Pharmaceutical Preparations; Piperidines; Rats; Rodentia; Sleep; Sleep Initiation and Maintenance Disorders; Triazoles | 2020 |
The Dual Orexin Receptor Antagonist DORA-22 Improves Mild Stress-induced Sleep Disruption During the Natural Sleep Phase of Nocturnal Rats.
Topics: Animals; Orexin Receptor Antagonists; Orexin Receptors; Piperidines; Rats; Sleep; Triazoles | 2021 |