Page last updated: 2024-08-24

triazoles and dinoprostone

triazoles has been researched along with dinoprostone in 53 studies

Research

Studies (53)

TimeframeStudies, this research(%)All Research%
pre-19902 (3.77)18.7374
1990's20 (37.74)18.2507
2000's15 (28.30)29.6817
2010's13 (24.53)24.3611
2020's3 (5.66)2.80

Authors

AuthorsStudies
de Lima, WT; Jancar, S; Sirois, P1
Cardillo, R; DiMuzio, J; Post, TJ; Raible, DG; Schulman, ES1
Brecht, HM; Helmchen, UM; Oberle, G; Schoeppe, W; Stahl, RA; Thaiss, F; Wenzel, U1
Brain, SD; Buckley, TL; Collins, PD; Williams, TJ1
Catto-Smith, AG; Gall, DG; MacNaughton, WK1
Gall, DG; MacNaughton, WK1
Phillips, WA; Stewart, AG1
Benveniste, J; Brink, C; Brunelleschi, S; Fantozzi, R; Giotti, A; Ledda, F; Renzi, D1
Abdi-Dezfuli, F; Gislason, H; Svanes, K; Sørbye, H; Waldum, HL1
Chandel, B; Deshpande, Y; Kaminski, DL; Kulkarni, A; Longo, WE; Niehoff, M; Polities, G; Vernava, AM1
Alami, N; de Brum-Fernandes, AJ; Müller, E; Rola-Pleszczynski, M; Thivierge, M1
Bazan, HE; Hurst, JS1
Egido, J; González, E; Gutierrez, S; Herrero-Beaumont, G; Miguélez, R; Navarro, F; Palacios, I; Sanchez-Pernaute, O1
Baba, A; Fukuda, S; Makino, H; Nagai, H; Ohta, Y; Sohda, T; Tsukuda, R1
Järvinen, TA; Järvinen, TL; Moilanen, E; Moilanen, T1
Asano, K; Bitoh, H; Imaki, H; Kurokawa, K; Nakao, A; Nosaka, K; Shimizu, T; Suzuki, T; Taniguchi, S; Watanabe, T1
Alper, CM; Burckart, GJ; Diven, WF; Doyle, WJ; Evans, RW; Jaffe, R1
Ichinowatari, G; Ohuchi, K; Tanimoto, A; Yaginuma, H; Yamada, M2
Shirasawa, E; Tsuji, F1
Annala, K; Asmawi, MZ; Kankaanranta, H; Moilanen, E; Rahkonen, P1
Brunsden, AM; Grundy, D1
Bulun, SE; Sasano, H; Takayama, K; Zeitoun, KM1
Bulun, SE; Takayama, K1
Purohit, A; Reed, MJ1
Ichinowatari, G; Ohuchi, K; Tanimoto, A; Tsuyuki, K; Yaginuma, H; Yamada, M1
Blankenstein, MA; Blijham, GH; Brodie, AM; Chen, T; DeJong, PC; Elbers, JR; Fulton, A; Long, BJ; Lu, Q; Macpherson, N; Nortier, JW; Schipper, ME; Slee, PH; Thijssen, JH; van de Ven, J; van Gorp, JM1
Alcaraz, MJ; Aller, E; Fernández, P; Guillén, MI; López-Cremades, P; Lorenzo, A; Molina, P; Ubeda, A1
Goss, PE; Strasser-Weippl, K1
Kohn, EC; Liotta, LA; Mehta, AI; Petricoin, EF; Winters, ME1
Kamio, K; Kawasaki, S; Kobayashi, T; Liu, X; Mao, LJ; Rennard, SI; Shen, L; Sugiura, H; Togo, S; Wang, XQ1
Chen, XB; Cherukuri, DP; Goulet, AC; Han, Y; Heimark, RL; Meuillet, E; Nelson, MA; Regan, JW; Young, RN1
Cicha, MZ; Hökfelt, T; Kopp, UC; Mulder, J; Smith, LA1
Han, M; Kim, JM; Kim, JY; Lee, KS; Park, JE1
Burnett-Bowie, SA; Dere, ME; Leder, BZ; Lee, H; Roupenian, KC1
Jin, M; Koizumi, S; Linden, J; Odashima, M; Ohnishi, H; Otaka, M; Watanabe, S1
Barnett, JM; Clark, ML; Penn, JS; Yanni, SE1
Andrade, LN; Chammas, R; de Oliveira, SI; Fernandes, PD; Jancar, S; Nonogaki, S; Onuchic, AC; Pinheiro, MC; Rohde, CB1
De Luca, A; Dello Russo, C; Lisi, L; Navarra, P; Tramutola, A1
Fuskevåg, OM; Gogvadze, V; Johnsen, JI; Kock, A; Kogner, P; Kruspig, B; Rasmuson, A; Simón-Santamaría, J; Sveinbjörnsson, B1
Li, X; Li, Y; Tan, L; Tang, T; Wang, J; Wu, Y; Xu, Z; Yang, P; Zhao, L; Zhao, Z1
Gu, Y; Han, Y; Ma, G; Shi, H; Tang, C; Wang, Q; Yan, G1
Jin, YH; Jin, Z; Kim, S; Lee, G; Park, CS; Park, YS1
Gallego, D; Jimenez, M; Mañé, N; Martin, MT; Martinez-Cutillas, M1
Cai, Y; Libby, P; Rocha, VZ; Shimizu, K; Sukhova, GK; Tang, EH; Vanhoutte, PM; Wong, CK; Xu, A; Xuan, G1
Bonewald, L; Brotto, M; Igwe, O; Mo, C; Vallejo, J; Wetmore, L; Zhao, R1
Allison, S; Hoang, KG; Murray, M; Petrovic, N1
Chow, KBS; Tse, KH; Wise, H1
Han, G; Li, W; Li, X; Yang, B1
Chen, L; Li, D; Wu, X; Zhong, J1
Cardoso, CS; Costa, EA; Dos Santos, FCA; Fajemiroye, JO; Florentino, IF; Lião, LM; Lima, DDS; Menegatti, R; Moreira, LKS; Sanz, G; Silva, DM; Silva, DPB; Vasconcelos, JP; Vaz, BG1
Aslam, T; Basha, FZ; Choudhary, MI; Iqbal, S; Jahan, H; Khan, MA; Siddiqui, NN1
Basha, FZ; Choudhary, MI; Iqbal, S; Jahan, H; Pizzi, M; Shaikh, S; Siddiqui, NN1

Reviews

3 review(s) available for triazoles and dinoprostone

ArticleYear
Estrogen biosynthesis in endometriosis: molecular basis and clinical relevance.
    Journal of molecular endocrinology, 2000, Volume: 25, Issue:1

    Topics: Anastrozole; Aromatase; Aromatase Inhibitors; Dinoprostone; Endometriosis; Enzyme Inhibitors; Estrogens; Estrone; Female; Humans; Middle Aged; Mullerian Ducts; Nitriles; Pregnancy; Triazoles

2000
[Endometriosis and aromatase inhibitor].
    Nihon rinsho. Japanese journal of clinical medicine, 2001, Volume: 59 Suppl 1

    Topics: Anastrozole; Aromatase; Aromatase Inhibitors; Dinoprostone; Endometriosis; Enzyme Inhibitors; Estrogen Antagonists; Estrogens; Fadrozole; Female; Humans; Middle Aged; Nitriles; Triazoles

2001
Aromatase regulation and breast cancer.
    Clinical endocrinology, 2001, Volume: 54, Issue:5

    Topics: 2-Methoxyestradiol; Adult; Animals; Aromatase; Aromatase Inhibitors; Aryl Hydrocarbon Hydroxylases; Breast; Breast Neoplasms; Cytochrome P-450 CYP2D6; Cytochrome P-450 Enzyme System; Cytokines; Dietary Fats; Dinoprostone; Enzyme Activation; Enzyme Inhibitors; Estradiol; Estrogens; Female; Fibroblasts; Humans; Letrozole; Middle Aged; Nitriles; Obesity; Pesticides; Steroid 16-alpha-Hydroxylase; Steroid Hydroxylases; Triazoles

2001

Trials

1 trial(s) available for triazoles and dinoprostone

ArticleYear
Effects of aromatase inhibition in hypogonadal older men: a randomized, double-blind, placebo-controlled trial.
    Clinical endocrinology, 2009, Volume: 70, Issue:1

    Topics: Aged; Anastrozole; Aromatase Inhibitors; Biological Availability; Body Composition; Dinoprostone; Double-Blind Method; Humans; Hypogonadism; Male; Middle Aged; Nitriles; Outcome Assessment, Health Care; Testosterone; Triazoles

2009

Other Studies

49 other study(ies) available for triazoles and dinoprostone

ArticleYear
Immune-complex alveolitis in the rat: evidence for platelet activating factor and leukotrienes as mediators of the vascular lesions.
    European journal of pharmacology, 1992, Mar-17, Volume: 213, Issue:1

    Topics: Alveolitis, Extrinsic Allergic; Animals; Azepines; Bronchoalveolar Lavage Fluid; Dinoprostone; Diterpenes; Econazole; Ginkgolides; Hemoglobins; Hemorrhage; Indomethacin; Lactones; Leukotriene B4; Leukotrienes; Lipoxygenase Inhibitors; Male; Platelet Activating Factor; Propionates; Quinolines; Rats; Rats, Inbred Strains; Thromboxanes; Triazoles

1992
Mast cell mediators prostaglandin-D2 and histamine activate human eosinophils.
    Journal of immunology (Baltimore, Md. : 1950), 1992, Jun-01, Volume: 148, Issue:11

    Topics: Azepines; Calcimycin; Calcium; Cytosol; Dinoprostone; Eosinophils; Histamine; Histamine Antagonists; Humans; In Vitro Techniques; Lung; Mast Cells; Neutrophils; Piperidines; Platelet Activating Factor; Prostaglandin D2; Secretory Rate; SRS-A; Triazoles

1992
The platelet activating factor receptor antagonist WEB 2170 improves glomerular hemodynamics and morphology in a proliferative model of mesangial cell injury.
    Journal of the American Society of Nephrology : JASN, 1991, Volume: 2, Issue:1

    Topics: Animals; Antilymphocyte Serum; Azepines; Dinoprostone; Disease Models, Animal; Glomerular Filtration Rate; Glomerular Mesangium; Glomerulonephritis; Inulin; Male; Platelet Membrane Glycoproteins; Rats; Rats, Inbred Strains; Receptors, Cell Surface; Receptors, G-Protein-Coupled; Thromboxane B2; Triazoles

1991
Inflammatory edema induced by interactions between IL-1 and the neuropeptide calcitonin gene-related peptide.
    Journal of immunology (Baltimore, Md. : 1950), 1991, May-15, Volume: 146, Issue:10

    Topics: Animals; Azepines; Calcitonin Gene-Related Peptide; Capillary Permeability; Complement C5a; Dinoprostone; Drug Synergism; Edema; Histamine H1 Antagonists; In Vitro Techniques; Interleukin-1; Male; Neutrophils; Platelet Activating Factor; Protein Synthesis Inhibitors; Rabbits; Triazoles

1991
A role for phospholipid-derived inflammatory mediators in intestinal anaphylaxis in the rat.
    The Journal of pharmacology and experimental therapeutics, 1992, Volume: 260, Issue:2

    Topics: Anaphylaxis; Animals; Azepines; Biological Transport; Carbazoles; Dinoprostone; Electrolytes; Female; Hydroxyeicosatetraenoic Acids; In Vitro Techniques; Jejunum; Leukotriene Antagonists; Leukotrienes; Phospholipids; Platelet Activating Factor; Propionates; Quinolines; Rats; Thromboxanes; Triazoles

1992
Mechanisms of platelet-activating factor-induced electrolyte transport in the rat jejunum.
    European journal of pharmacology, 1991, Jul-23, Volume: 200, Issue:1

    Topics: Animals; Arachidonic Acids; Azepines; Biological Transport, Active; Chlorides; Dinoprostone; Eicosanoic Acids; Electrophysiology; Female; Indomethacin; Jejunum; Platelet Activating Factor; Quinacrine; Rats; Triazoles

1991
Intracellular platelet-activating factor regulates eicosanoid generation in guinea-pig resident peritoneal macrophages.
    British journal of pharmacology, 1989, Volume: 98, Issue:1

    Topics: 6-Ketoprostaglandin F1 alpha; Animals; Arachidonic Acid; Arachidonic Acids; Azepines; Calcimycin; Chromatography, High Pressure Liquid; Culture Media; Dinoprostone; Eicosanoids; Guinea Pigs; In Vitro Techniques; Macrophages; Male; N-Formylmethionine Leucyl-Phenylalanine; Peritoneal Cavity; Platelet Activating Factor; Superoxides; Triazines; Triazoles

1989
Interference of WEB 2086 and BN 52021 with Paf-induced effects on guinea-pig trachea.
    British journal of pharmacology, 1989, Volume: 97, Issue:2

    Topics: Animals; Azepines; Dinoprostone; Diterpenes; Ginkgolides; Guinea Pigs; Histamine Antagonists; In Vitro Techniques; Lactones; Male; Muscle Relaxation; Muscle, Smooth; Platelet Activating Factor; Trachea; Triazines; Triazoles

1989
Role of prostaglandins and histamine in hyperemic response to superficial and deep gastric mucosal injury and H+ back-diffusion in cats.
    Digestive diseases and sciences, 1995, Volume: 40, Issue:8

    Topics: 6-Ketoprostaglandin F1 alpha; Animals; Astemizole; Cats; Dinoprostone; Gastric Acid; Gastric Mucosa; Histamine; Histamine H2 Antagonists; Hyperemia; Indomethacin; Male; Prostaglandins; Regional Blood Flow; Saline Solution, Hypertonic; Triazoles

1995
Platelet-activating factor mediates trinitrobenzene induced colitis.
    Prostaglandins, leukotrienes, and essential fatty acids, 1994, Volume: 51, Issue:6

    Topics: 6-Ketoprostaglandin F1 alpha; Animals; Azepines; Colitis; Colon; Dinoprostone; Eicosanoids; Gastrointestinal Contents; Leukotriene B4; Platelet Activating Factor; Rabbits; Second Messenger Systems; Thromboxane B2; Triazoles; Trinitrobenzenesulfonic Acid

1994
Transcriptional modulation of platelet-activating factor receptor gene expression by cyclic AMP.
    The Journal of biological chemistry, 1993, Aug-15, Volume: 268, Issue:23

    Topics: Animals; Azepines; Bucladesine; Calcium; Cell Membrane; Cells, Cultured; Cricetinae; Cyclic AMP; Cycloheximide; Dinoprostone; Flow Cytometry; Gene Expression Regulation; Humans; Kinetics; Monocytes; Platelet Activating Factor; Platelet Membrane Glycoproteins; Receptors, Cell Surface; Receptors, G-Protein-Coupled; RNA, Messenger; Transcription, Genetic; Triazoles

1993
Platelet-activating factor preferentially stimulates the phospholipase A2/cyclooxygenase cascade in the rabbit cornea.
    Current eye research, 1995, Volume: 14, Issue:9

    Topics: Animals; Arachidonic Acid; Azepines; Cornea; Dinoprostone; Female; In Vitro Techniques; Male; Phospholipases A; Phospholipases A2; Platelet Activating Factor; Prostaglandin-Endoperoxide Synthases; Rabbits; Thienopyridines; Triazoles

1995
Anti-inflammatory effect of a PAF receptor antagonist and a new molecule with antiproteinase activity in an experimental model of acute urate crystal arthritis.
    Journal of lipid mediators and cell signalling, 1996, Volume: 13, Issue:1

    Topics: Acute Disease; Animals; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Gouty; Azepines; C-Reactive Protein; Dinoprostone; Disease Models, Animal; Indenes; Interleukin-6; Joints; Platelet Activating Factor; Platelet Aggregation Inhibitors; Platelet Membrane Glycoproteins; Protease Inhibitors; Rabbits; Random Allocation; Receptors, Cell Surface; Receptors, G-Protein-Coupled; Synovial Fluid; Thienopyridines; Triazoles; Tumor Necrosis Factor-alpha; Uric Acid

1996
Immunomodulating and articular protecting activities of a new anti-rheumatic drug, TAK-603.
    Immunopharmacology, 1996, Volume: 34, Issue:1

    Topics: Adjuvants, Immunologic; Animals; Antirheumatic Agents; Arthritis, Experimental; Autoimmune Diseases; Cartilage; Cells, Cultured; Cytokines; Dinoprostone; Extracellular Matrix; Interleukin-1; Male; Mice; Mice, Inbred BALB C; Mice, Inbred ICR; Quinolines; Rabbits; Radiography; Rats; Rats, Inbred Lew; Rats, Sprague-Dawley; Spleen; Triazoles

1996
Endogenous nitric oxide and prostaglandin E2 do not regulate the synthesis of each other in interleukin-1 beta-stimulated rat articular cartilage.
    Inflammation, 1996, Volume: 20, Issue:6

    Topics: Animals; Aspirin; Cartilage, Articular; Dexamethasone; Dinoprostone; Electron Transport Complex IV; Interleukin-1; Ketoprofen; Kinetics; Male; Molsidomine; Nitric Oxide; Nitric Oxide Synthase; omega-N-Methylarginine; Organ Culture Techniques; Ornithine; Prostaglandin Antagonists; Rats; Rats, Wistar; Triazoles

1996
cAMP mediates homologous downregulation of PAF receptor mRNA expression in mesangial cells.
    The American journal of physiology, 1997, Volume: 273, Issue:3 Pt 2

    Topics: Animals; Azepines; Cyclic AMP; Cyclooxygenase Inhibitors; Dinoprostone; Down-Regulation; Female; Glomerular Mesangium; Indomethacin; Kinetics; Platelet Activating Factor; Platelet Membrane Glycoproteins; Rats; Rats, Sprague-Dawley; Receptors, Cell Surface; Receptors, G-Protein-Coupled; RNA, Messenger; Signal Transduction; Transcription, Genetic; Triazoles; Virulence Factors, Bordetella

1997
Expression of acute otitis media after receptor blockade of platelet activating factor, thromboxane, and leukotrienes in the chinchilla.
    The Annals of otology, rhinology, and laryngology, 1998, Volume: 107, Issue:3

    Topics: 6-Ketoprostaglandin F1 alpha; Acute Disease; Animals; Azepines; Biphenyl Compounds; Chinchilla; Dinoprostone; Ear, Middle; Fatty Acids, Nonesterified; Heptanoic Acids; Hydrolases; Leukotriene Antagonists; Leukotriene C4; Mucous Membrane; Otitis Media; Phospholipids; Platelet Activating Factor; Platelet Membrane Glycoproteins; Pneumococcal Infections; Propionates; Quinolines; Receptors, Cell Surface; Receptors, G-Protein-Coupled; Receptors, Thromboxane; Thromboxane B2; Triazoles

1998
Inhibition of tumor necrosis factor-alpha production by SK&F 98625, a CoA-independent transacylase inhibitor, in cultured rat peritoneal macrophages.
    Life sciences, 1998, Volume: 62, Issue:20

    Topics: Acyltransferases; Animals; Azepines; Cells, Cultured; Dinoprostone; Enzyme Inhibitors; Furans; Imidazoles; Macrophages, Peritoneal; Male; Organophosphorus Compounds; Platelet Activating Factor; Platelet Aggregation Inhibitors; Pyridinium Compounds; Rats; Rats, Sprague-Dawley; Specific Pathogen-Free Organisms; Thapsigargin; Triazoles; Tumor Necrosis Factor-alpha

1998
The role of platelet-activating factor in cell infiltration in endotoxin-induced uveitis in guinea pigs.
    Current eye research, 1998, Volume: 17, Issue:5

    Topics: Animals; Anterior Chamber; Aqueous Humor; Azepines; Betamethasone; Chemotaxis, Leukocyte; Dinoprostone; Escherichia coli; Flow Cytometry; Guinea Pigs; Indomethacin; Leukocyte Count; Leukocytes; Lipopolysaccharides; Male; Ophthalmic Solutions; Platelet Activating Factor; Platelet Aggregation Inhibitors; Triazoles; Uveitis, Anterior

1998
Possible participation of intracellular platelet-activating factor in tumor necrosis factor-alpha production by rat peritoneal macrophages.
    European journal of pharmacology, 1999, Jun-25, Volume: 374, Issue:3

    Topics: Animals; Azepines; Cells, Cultured; Dinoprostone; Enzyme Inhibitors; Furans; Imidazoles; Indomethacin; Macrophages, Peritoneal; Male; Organophosphorus Compounds; Platelet Activating Factor; Pyridinium Compounds; Rats; Rats, Sprague-Dawley; RNA, Messenger; Thapsigargin; Triazoles; Tumor Necrosis Factor-alpha

1999
Effects of nitric oxide donors GEA 3162 and SIN-1 on ethanol-induced gastric ulceration in rats.
    European journal of pharmacology, 1999, Jul-28, Volume: 378, Issue:1

    Topics: Animals; Blood Pressure; Dinoprostone; Ethanol; Gastric Mucosa; Male; Molsidomine; Nitric Oxide Donors; Rats; Rats, Wistar; Stomach Ulcer; Triazoles

1999
Sensitization of visceral afferents to bradykinin in rat jejunum in vitro.
    The Journal of physiology, 1999, Dec-01, Volume: 521 Pt 2

    Topics: Adenosine; Animals; Bradykinin; Bucladesine; Cyclooxygenase Inhibitors; Dinoprostone; Histamine; Histamine Antagonists; Histamine H2 Antagonists; In Vitro Techniques; Jejunum; Male; Membrane Potentials; Naproxen; Neurons, Afferent; Piperidines; Ranitidine; Rats; Rats, Inbred Strains; Serotonin; Stimulation, Chemical; Triazines; Triazoles; Xanthines

1999
Participation of prostaglandin E2 and platelet-activating factor in thapsigargin-induced production of interleukin-6.
    European journal of pharmacology, 2002, Jan-11, Volume: 434, Issue:3

    Topics: Acetyltransferases; Acyl-Carrier Protein S-Acetyltransferase; Animals; Azepines; Cells, Cultured; Dinoprostone; Dose-Response Relationship, Drug; Drug Synergism; Enzyme Inhibitors; Furans; Imidazoles; Indomethacin; Interleukin-6; Macrophages, Peritoneal; Male; Organophosphorus Compounds; Platelet Activating Factor; Platelet Membrane Glycoproteins; Rats; Rats, Sprague-Dawley; Receptors, Cell Surface; Receptors, G-Protein-Coupled; RNA, Messenger; Thapsigargin; Triazoles

2002
Aromatase and COX-2 expression in human breast cancers.
    The Journal of steroid biochemistry and molecular biology, 2001, Volume: 79, Issue:1-5

    Topics: Adipocytes; Adult; Aged; Aged, 80 and over; Animals; Aromatase; Aromatase Inhibitors; Breast Neoplasms; Cyclooxygenase 2; Dinoprostone; Endothelium; Enzyme Inhibitors; Epithelial Cells; Estrogen Receptor Modulators; Estrogens; Female; Humans; Immunohistochemistry; Isoenzymes; Letrozole; Mammary Neoplasms, Experimental; Membrane Proteins; Mice; Mice, Inbred BALB C; Middle Aged; Neoplasms, Hormone-Dependent; Nitriles; Prostaglandin-Endoperoxide Synthases; Stromal Cells; Tamoxifen; Triazoles

2001
A novel indazolo-triazolo-benzotriazepine exerts anti-inflammatory effects by inhibition of cyclooxygenase-2 activity and nitric oxide synthase-2 expression.
    Naunyn-Schmiedeberg's archives of pharmacology, 2003, Volume: 368, Issue:1

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Azepines; Blood Platelets; Blotting, Western; Carrageenan; Cell Survival; Cells, Cultured; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Dinoprostone; Edema; Electrophoretic Mobility Shift Assay; Female; Humans; Indazoles; Isoenzymes; Macrophages; Membrane Proteins; Mice; Microsomes; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Nitrites; Prostaglandin-Endoperoxide Synthases; Triazoles

2003
Prevention strategies with aromatase inhibitors.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2004, Jan-01, Volume: 10, Issue:1 Pt 2

    Topics: Anastrozole; Antineoplastic Agents, Hormonal; Aromatase Inhibitors; Breast Neoplasms; Clinical Trials as Topic; Cyclooxygenase 2; Dinoprostone; Enzyme Inhibitors; Female; Humans; Isoenzymes; Membrane Proteins; Models, Biological; Neoplasms; Nitriles; Placebos; Postmenopause; Prostaglandin-Endoperoxide Synthases; Receptors, Estrogen; Tamoxifen; Time Factors; Triazoles

2004
Supra-additive growth inhibition by a celecoxib analogue and carboxyamido-triazole is primarily mediated through apoptosis.
    Cancer research, 2005, May-01, Volume: 65, Issue:9

    Topics: Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Calcium Channel Blockers; Celecoxib; Cell Cycle; Cell Line, Tumor; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Dinoprostone; Drug Screening Assays, Antitumor; Drug Synergism; ErbB Receptors; Humans; Indoles; Membrane Proteins; Prostaglandin-Endoperoxide Synthases; Pyrazoles; Signal Transduction; Sulfonamides; Transcriptional Activation; Triazoles

2005
Prostaglandin E(2) protects human lung fibroblasts from cigarette smoke extract-induced apoptosis via EP(2) receptor activation.
    Journal of cellular physiology, 2007, Volume: 210, Issue:1

    Topics: Adenylyl Cyclase Inhibitors; Adenylyl Cyclases; Alprostadil; Apoptosis; Carbazoles; Caspases; Cell Line; Cyclic AMP-Dependent Protein Kinases; Dideoxyadenosine; Dinoprostone; Dose-Response Relationship, Drug; Enzyme Activation; Enzyme Inhibitors; Fibroblasts; Humans; Indoles; Lung; Nicotiana; Pyrroles; Receptors, Prostaglandin E; Receptors, Prostaglandin E, EP2 Subtype; RNA, Small Interfering; Signal Transduction; Smoke; Thiophenes; Triazoles

2007
The EP4 receptor antagonist, L-161,982, blocks prostaglandin E2-induced signal transduction and cell proliferation in HCA-7 colon cancer cells.
    Experimental cell research, 2007, Aug-15, Volume: 313, Issue:14

    Topics: Animals; Cell Line, Tumor; Cell Proliferation; Colonic Neoplasms; Cyclic AMP Response Element-Binding Protein; Dinoprostone; Early Growth Response Protein 1; Extracellular Signal-Regulated MAP Kinases; Humans; Promoter Regions, Genetic; Receptors, Prostaglandin E; Receptors, Prostaglandin E, EP4 Subtype; Signal Transduction; Thiophenes; Transcription, Genetic; Triazoles

2007
Renal sympathetic nerve activity modulates afferent renal nerve activity by PGE2-dependent activation of alpha1- and alpha2-adrenoceptors on renal sensory nerve fibers.
    American journal of physiology. Regulatory, integrative and comparative physiology, 2007, Volume: 293, Issue:4

    Topics: Adrenergic alpha-1 Receptor Antagonists; Adrenergic alpha-2 Receptor Antagonists; Adrenergic Fibers; Animals; Calcitonin Gene-Related Peptide; Dinoprostone; Indomethacin; Kidney; Male; Neurons, Afferent; Neurons, Efferent; Norepinephrine; Norepinephrine Plasma Membrane Transport Proteins; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, alpha-1; Receptors, Adrenergic, alpha-2; Receptors, Prostaglandin E; Receptors, Prostaglandin E, EP4 Subtype; Substance P; Thiophenes; Triazoles

2007
Effects of letrozole on proliferation and apoptosis in cultured leiomyoma cells treated with prostaglandin E(2).
    European journal of obstetrics, gynecology, and reproductive biology, 2008, Volume: 138, Issue:1

    Topics: Apoptosis; Aromatase Inhibitors; Cell Proliferation; Cells, Cultured; Dinoprostone; Enzyme Activators; Female; Humans; Hysterectomy; Leiomyoma; Letrozole; Nitriles; Triazoles

2008
Attenuation of gastric mucosal inflammation induced by indomethacin through activation of the A2A adenosine receptor in rats.
    Journal of gastroenterology, 2009, Volume: 44, Issue:5

    Topics: Adenosine A2 Receptor Agonists; Adenosine A2 Receptor Antagonists; Animals; Anti-Inflammatory Agents, Non-Steroidal; Chemokine CXCL1; Dinoprostone; Gastric Mucosa; Indomethacin; Inflammation; Interleukin-1beta; Male; Peroxidase; Piperidines; Rats; Rats, Sprague-Dawley; Receptor, Adenosine A2A; Stomach Ulcer; Triazines; Triazoles; Tumor Necrosis Factor-alpha

2009
The role of PGE2 receptor EP4 in pathologic ocular angiogenesis.
    Investigative ophthalmology & visual science, 2009, Volume: 50, Issue:11

    Topics: Animals; Animals, Newborn; Cell Proliferation; Choroid; Choroidal Neovascularization; Cyclooxygenase 2; Dinoprostone; Disease Models, Animal; Endothelium, Vascular; Enzyme-Linked Immunosorbent Assay; Humans; Laser Coagulation; Male; Mice; Neuroglia; Oxygen; Rats; Rats, Inbred BN; Rats, Sprague-Dawley; Receptors, Prostaglandin E; Receptors, Prostaglandin E, EP4 Subtype; Retinal Neovascularization; Retinal Vessels; Thiophenes; Triazoles; Vascular Endothelial Growth Factor A

2009
Platelet-activating factor receptor (PAF-R)-dependent pathways control tumour growth and tumour response to chemotherapy.
    BMC cancer, 2010, May-13, Volume: 10

    Topics: Animals; Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Azepines; Carcinoma, Ehrlich Tumor; Caspase 3; Cell Proliferation; Cyclooxygenase 2; Dacarbazine; Dinoprostone; Enzyme-Linked Immunosorbent Assay; Female; Flow Cytometry; Galectin 3; Immunohistochemistry; Macrophages; Male; Melanoma, Experimental; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Neovascularization, Pathologic; Nitric Oxide; Phenotype; Platelet Membrane Glycoproteins; Receptors, G-Protein-Coupled; Signal Transduction; Time Factors; Triazoles; Tumor Burden; Vascular Endothelial Growth Factor A

2010
Modulatory effects of the CCR5 antagonist maraviroc on microglial pro-inflammatory activation elicited by gp120.
    Journal of neurochemistry, 2012, Volume: 120, Issue:1

    Topics: Animals; Blotting, Western; CCR5 Receptor Antagonists; Cell Survival; Cells, Cultured; Cyclohexanes; Cytokines; Dinoprostone; DNA Primers; HIV Envelope Protein gp120; HIV Infections; Inflammation; Interferon-gamma; Macrophage Activation; Maraviroc; Microglia; Nitric Oxide; Rats; Real-Time Polymerase Chain Reaction; RNA, Messenger; Triazoles

2012
Autocrine prostaglandin E2 signaling promotes tumor cell survival and proliferation in childhood neuroblastoma.
    PloS one, 2012, Volume: 7, Issue:1

    Topics: 16,16-Dimethylprostaglandin E2; Autocrine Communication; Biphenyl Compounds; Blotting, Western; Calcium; Cell Line, Tumor; Cell Proliferation; Cell Survival; Cyclic AMP; Cyclooxygenase 2 Inhibitors; Dinoprostone; Humans; Immunohistochemistry; In Vitro Techniques; Neuroblastoma; Phosphorylation; Receptors, Prostaglandin E, EP1 Subtype; Receptors, Prostaglandin E, EP2 Subtype; Receptors, Prostaglandin E, EP3 Subtype; Receptors, Prostaglandin E, EP4 Subtype; Reverse Transcriptase Polymerase Chain Reaction; Tandem Mass Spectrometry; Thiophenes; Triazoles

2012
Coculture with endothelial cells enhances osteogenic differentiation of periodontal ligament stem cells via cyclooxygenase-2/prostaglandin E2/vascular endothelial growth factor signaling under hypoxia.
    Journal of periodontology, 2013, Volume: 84, Issue:12

    Topics: Angiogenesis Inhibitors; Cell Culture Techniques; Cell Differentiation; Cell Hypoxia; Coculture Techniques; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Dinoprostone; Endothelial Cells; Flavonoids; Human Umbilical Vein Endothelial Cells; Humans; Indoles; Nitrobenzenes; Osteogenesis; Periodontal Ligament; Prostaglandin Antagonists; Protein Kinase Inhibitors; Pyrroles; Signal Transduction; Stem Cells; Sulfonamides; Thiophenes; Triazoles; Vascular Endothelial Growth Factor A; Xanthones

2013
Regulation of rat intrapulmonary arterial tone by arachidonic acid and prostaglandin E2 during hypoxia.
    PloS one, 2013, Volume: 8, Issue:8

    Topics: Animals; Arachidonic Acid; Calcium; Cyclic AMP; Cyclooxygenase 2; Dinoprostone; Hypoxia; Male; Muscle Tonus; Oxytocics; Pulmonary Artery; Rats; Rats, Wistar; Receptors, Prostaglandin E; Thiophenes; Triazoles; Vasoconstriction; Xanthones

2013
Prostaglandin potentiates 5-HT responses in stomach and ileum innervating visceral afferent sensory neurons.
    Biochemical and biophysical research communications, 2015, Jan-02, Volume: 456, Issue:1

    Topics: Animals; Anti-Inflammatory Agents; Carbazoles; Dinoprostone; Dose-Response Relationship, Drug; Gastrointestinal Diseases; Ileum; Male; Neurons, Afferent; Nodose Ganglion; Ondansetron; Patch-Clamp Techniques; Prostaglandins; Pyrroles; Rats; Rats, Sprague-Dawley; Receptors, Serotonin, 5-HT3; Sensory Receptor Cells; Serotonin; Signal Transduction; Stomach; Thiophenes; Triazoles; Visceral Afferents; Xanthones

2015
EP2 and EP4 receptors mediate PGE2 induced relaxation in murine colonic circular muscle: pharmacological characterization.
    Pharmacological research, 2014, Volume: 90

    Topics: Alprostadil; Animals; Azetidines; Colon; Dinoprostone; Female; In Vitro Techniques; Male; Mice, Knockout; Muscle Contraction; Muscle, Smooth; Receptors, Prostaglandin E, EP2 Subtype; Receptors, Prostaglandin E, EP4 Subtype; Thiophenes; Triazoles

2014
Activation of prostaglandin E2-EP4 signaling reduces chemokine production in adipose tissue.
    Journal of lipid research, 2015, Volume: 56, Issue:2

    Topics: Adipose Tissue; Animals; Chemokine CCL3; Chemokine CXCL10; Chemokines; Dinoprostone; In Vitro Techniques; Interleukin-10; Interleukin-6; Interleukin-8; Male; Pyrrolidinones; Receptors, Prostaglandin E, EP4 Subtype; Serum Amyloid A Protein; Signal Transduction; Tetrazoles; Thiophenes; Triazoles

2015
Prostaglandin E2 promotes proliferation of skeletal muscle myoblasts via EP4 receptor activation.
    Cell cycle (Georgetown, Tex.), 2015, Volume: 14, Issue:10

    Topics: Acetylcysteine; Alprostadil; Animals; Cell Proliferation; Cells, Cultured; Dinoprostone; G1 Phase Cell Cycle Checkpoints; Immunohistochemistry; Mice; Mice, Inbred C57BL; Muscle, Skeletal; Myoblasts; Reactive Oxygen Species; Receptors, Prostaglandin E, EP1 Subtype; Receptors, Prostaglandin E, EP2 Subtype; Receptors, Prostaglandin E, EP3 Subtype; Receptors, Prostaglandin E, EP4 Subtype; Signal Transduction; Thiophenes; Triazoles

2015
Prostanoids regulate angiogenesis acting primarily on IP and EP4 receptors.
    Microvascular research, 2015, Volume: 101

    Topics: Benzyl Compounds; Cell Movement; Dinoprostone; Endothelial Cells; Epoprostenol; Gene Expression Regulation; Human Umbilical Vein Endothelial Cells; Humans; Imidazoles; Neovascularization, Pathologic; Neovascularization, Physiologic; Prostaglandins I; Real-Time Polymerase Chain Reaction; Receptors, Epoprostenol; Receptors, G-Protein-Coupled; Receptors, Prostaglandin E, EP4 Subtype; Thiophenes; Triazoles; Xanthones

2015
PGE2 released by primary sensory neurons modulates Toll-like receptor 4 activities through an EP4 receptor-dependent process.
    Journal of neuroimmunology, 2016, Apr-15, Volume: 293

    Topics: Animals; Cells, Cultured; Culture Media, Conditioned; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Cyclooxygenase 2; Dinoprostone; Enzyme Inhibitors; Ganglia, Spinal; Gene Expression Regulation; Glial Fibrillary Acidic Protein; Lipopolysaccharide Receptors; Lipopolysaccharides; Male; Quinolines; Rats; Rats, Sprague-Dawley; Receptors, Prostaglandin E, EP4 Subtype; Sensory Receptor Cells; Sulfonamides; Thiophenes; Toll-Like Receptor 4; Triazoles; Tumor Necrosis Factor-alpha

2016
The EP4 antagonist, L-161,982, induces apoptosis, cell cycle arrest, and inhibits prostaglandin E2-induced proliferation in oral squamous carcinoma Tca8113 cells.
    Journal of oral pathology & medicine : official publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology, 2017, Volume: 46, Issue:10

    Topics: Apoptosis; Carcinoma, Squamous Cell; Cell Cycle Checkpoints; Cell Proliferation; Dinoprostone; Humans; Mouth Neoplasms; Receptors, Prostaglandin E, EP4 Subtype; Thiophenes; Triazoles; Tumor Cells, Cultured

2017
L161982 alleviates collagen-induced arthritis in mice by increasing Treg cells and down-regulating Interleukin-17 and monocyte-chemoattractant protein-1 levels.
    BMC musculoskeletal disorders, 2017, Nov-16, Volume: 18, Issue:1

    Topics: Animals; Ankle Joint; Arthritis, Experimental; Arthritis, Rheumatoid; Celecoxib; Cell Differentiation; Cell Proliferation; Chemokine CCL2; Collagen Type II; Cyclooxygenase 2 Inhibitors; Dinoprostone; Down-Regulation; Female; Humans; Injections, Intraperitoneal; Interleukin-17; Mice; Mice, Inbred DBA; Receptors, Prostaglandin E, EP4 Subtype; Severity of Illness Index; Signal Transduction; T-Lymphocytes, Regulatory; Th17 Cells; Thiophenes; Triazoles

2017
Mechanisms involved in the antinociceptive and anti-inflammatory effects of a new triazole derivative: 5-[1-(4-fluorophenyl)-1H-1,2,3-triazol-4-yl]-1H-tetrazole (LQFM-096).
    Inflammopharmacology, 2020, Volume: 28, Issue:4

    Topics: Analgesics; Animals; Anti-Inflammatory Agents; Carrageenan; Cell Movement; Dinoprostone; Edema; Female; Hyperalgesia; Leukocytes; Mice; Nociception; Pain Measurement; Pleurisy; Tetrazoles; Triazoles

2020
Indole-linked 1,2,3-triazole derivatives efficiently modulate COX-2 protein and PGE
    Life sciences, 2022, Feb-15, Volume: 291

    Topics: Cyclooxygenase 2; Cytokines; Dinoprostone; Glycation End Products, Advanced; Humans; Indoles; Inflammation; Inflammation Mediators; Monocytes; NF-kappa B; Reactive Oxygen Species; THP-1 Cells; Triazoles

2022
Suppression of COX-2/PGE
    Cellular signalling, 2022, Volume: 97

    Topics: Carbazoles; Cyclooxygenase 2; Diabetic Angiopathies; Dinoprostone; Glucose; Glycation End Products, Advanced; Humans; Monocytes; NF-kappa B; Pyruvaldehyde; Reactive Oxygen Species; Signal Transduction; Triazoles

2022