Page last updated: 2024-08-24

triazoles and colchicine

triazoles has been researched along with colchicine in 17 studies

Research

Studies (17)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (5.88)29.6817
2010's13 (76.47)24.3611
2020's3 (17.65)2.80

Authors

AuthorsStudies
Fernández de Henestrosa, AR; García, C; Guzmán, A; Marín, AP; Ruiz, MT; Tortajada, A1
Neudörfl, JM; Nicolaus, N; Oschkinat, H; Prokop, A; Riesterer, P; Schmalz, HG; Zapke, J1
Baraldi, PG; Basso, G; Bortolozzi, R; Brancale, A; Carrion, MD; Chen, L; Cruz-Lopez, O; Hamel, E; Lopez Cara, C; Romagnoli, R; Viola, G1
Boatto, G; Briguglio, I; Carta, A; Di Cristina, A; Fermeglia, M; Grimaudo, S; La Colla, P; Laurini, E; Loddo, R; Paneni, MS; Pipitone, RM; Piras, S; Posocco, P; Pricl, S; Tolomeo, M1
Baumgartner, S; Fleischmann, R; Hingorani, V; Kerr, B; Manhard, K; Miner, JN; Polvent, E; Quart, B; Shen, Z; Suster, M; Yeh, LT1
Aly, OM; Beshr, EA; Gamal-Eldeen, AM; Maklad, RM; Mustafa, M1
Baraldi, PG; Basso, G; Bertolasi, V; Brancale, A; Cancellieri, M; Castagliuolo, I; Consolaro, F; Hamel, E; Porcù, E; Prencipe, F; Romagnoli, R; Salvador, MK; Viola, G1
Bucci, G; Gillen, M; Kerr, B; Lee, C; Shen, Z; Tieu, K; Wilson, D1
Błauż, A; Ciszewski, WM; Kowalczyk, K; Plażuk, D; Rychlik, B; Wieczorek, A1
Ahmed, HEA; Alswah, M; Bayoumi, AH; Elgamal, K; Elmorsy, A; Ihmaid, S1
Baraldi, PG; Baraldi, S; Bortolozzi, R; Brancale, A; Ferla, S; Hamel, E; Oliva, P; Prencipe, F; Romagnoli, R; Viola, G1
Fields, TR1
Cui, XX; Fu, DJ; Li, P; Wu, BW; Zhang, SY; Zhao, CB1
Ansari, M; Emami, S; Fallah, M; Hashemi, SM; Karima, S; Mirzaei, H; Rajaei, S; Shokrzadeh, M1
Balasubramanian, R; Maideen, NMP1
Bagella, L; Bordoni, V; Carta, A; Ibba, R; Lai, M; Piras, S; Riu, F; Sanna, L; Sestito, S; Zoroddu, S1
Guan, Q; Hong, Y; Li, B; Li, M; Li, N; Li, X; Wu, L; Zhang, B; Zhang, W1

Reviews

2 review(s) available for triazoles and colchicine

ArticleYear
The Challenges of Approaching and Managing Gout.
    Rheumatic diseases clinics of North America, 2019, Volume: 45, Issue:1

    Topics: Acetamides; Allopurinol; Antibodies, Monoclonal, Humanized; Colchicine; Diet Therapy; Febuxostat; Gout; Gout Suppressants; Humans; Medication Adherence; Patient Education as Topic; Phenylacetates; Polyethylene Glycols; Quality of Health Care; Rheumatology; Thioglycolates; Triazoles; Urate Oxidase; Uric Acid

2019
HMG-CoA Reductase Inhibitors (Statins) and their Drug Interactions Involving CYP Enzymes, P-glycoprotein and OATP Transporters-An Overview.
    Current drug metabolism, 2021, Volume: 22, Issue:5

    Topics: Anti-Infective Agents; Anticonvulsants; Antiviral Agents; ATP Binding Cassette Transporter, Subfamily B, Member 1; Cardiovascular Agents; Colchicine; Contraceptives, Oral; Cytochrome P-450 CYP3A; Drug Interactions; Fibric Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Immunosuppressive Agents; Organic Anion Transporters; Phosphodiesterase 5 Inhibitors; Piperazines; Triazoles; Warfarin

2021

Trials

1 trial(s) available for triazoles and colchicine

ArticleYear
Pharmacodynamic, pharmacokinetic and tolerability evaluation of concomitant administration of lesinurad and febuxostat in gout patients with hyperuricaemia.
    Rheumatology (Oxford, England), 2014, Volume: 53, Issue:12

    Topics: Adult; Aged; Colchicine; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Therapy, Combination; Febuxostat; Female; Gout; Gout Suppressants; Humans; Hyperuricemia; Male; Middle Aged; Thiazoles; Thioglycolates; Triazoles; Uric Acid

2014

Other Studies

14 other study(ies) available for triazoles and colchicine

ArticleYear
Induction of micronuclei in mouse bone-marrow erythrocytes in association with hypothermia after administration of the sigma receptor ligand E-5842.
    Mutation research, 2004, Dec-31, Volume: 565, Issue:1

    Topics: Animals; Body Temperature; Bone Marrow Cells; Colchicine; Cyclophosphamide; Erythrocytes; Hypothermia; Male; Mice; Micronuclei, Chromosome-Defective; Micronucleus Tests; Molecular Structure; Mutagens; Pyridines; Triazoles

2004
Azides derived from colchicine and their use in library synthesis: A practical entry to new bioactive derivatives of an old natural drug.
    ChemMedChem, 2010, May-03, Volume: 5, Issue:5

    Topics: Antineoplastic Agents; Azides; Colchicine; Crystallography, X-Ray; HeLa Cells; Humans; Molecular Conformation; Triazoles; Tubulin Modulators

2010
Synthesis and antitumor activity of 1,5-disubstituted 1,2,4-triazoles as cis-restricted combretastatin analogues.
    Journal of medicinal chemistry, 2010, May-27, Volume: 53, Issue:10

    Topics: Angiogenesis Inhibitors; Animals; Antineoplastic Agents; Apoptosis; Bibenzyls; Caspase 3; Cell Line, Tumor; Cell Shape; Cells, Cultured; Chick Embryo; Colchicine; Drug Screening Assays, Antitumor; Endothelial Cells; Enzyme Activation; G2 Phase; Humans; Membrane Potential, Mitochondrial; Mitochondria; Models, Molecular; Poly(ADP-ribose) Polymerases; Protein Binding; Proto-Oncogene Proteins c-bcl-2; Reactive Oxygen Species; Structure-Activity Relationship; Triazoles; Tubulin; Tubulin Modulators

2010
3-Aryl-2-[1H-benzotriazol-1-yl]acrylonitriles: a novel class of potent tubulin inhibitors.
    European journal of medicinal chemistry, 2011, Volume: 46, Issue:9

    Topics: Acrylonitrile; Binding, Competitive; Cell Cycle; Colchicine; Gas Chromatography-Mass Spectrometry; Humans; K562 Cells; Magnetic Resonance Spectroscopy; Models, Molecular; Structure-Activity Relationship; Triazoles; Tubulin

2011
Synthesis, cytotoxicity, docking study, and tubulin polymerization inhibitory activity of novel 1-(3,4-dimethoxyphenyl)-5-(3,4,5-trimethoxyphenyl)-1H-1,2,4-triazole-3-carboxanilides.
    Archiv der Pharmazie, 2014, Volume: 347, Issue:9

    Topics: Anilides; Binding Sites; Cell Survival; Colchicine; Hep G2 Cells; HL-60 Cells; Humans; Hydrogen Bonding; Hydrophobic and Hydrophilic Interactions; Inhibitory Concentration 50; MCF-7 Cells; Microtubules; Molecular Docking Simulation; Molecular Structure; Structure-Activity Relationship; Triazoles; Tubulin Modulators

2014
Synthesis, antimitotic and antivascular activity of 1-(3',4',5'-trimethoxybenzoyl)-3-arylamino-5-amino-1,2,4-triazoles.
    Journal of medicinal chemistry, 2014, Aug-14, Volume: 57, Issue:15

    Topics: Angiogenesis Inhibitors; Aniline Compounds; Animals; Antimitotic Agents; Antineoplastic Agents; Apoptosis; Carcinoma, Hepatocellular; Cell Cycle; Cell Proliferation; Colchicine; Drug Resistance, Neoplasm; Drug Screening Assays, Antitumor; Human Umbilical Vein Endothelial Cells; Humans; Liver Neoplasms; Mice, Inbred BALB C; Models, Molecular; Neoplasm Transplantation; Neoplastic Stem Cells; Protein Binding; Stereoisomerism; Structure-Activity Relationship; Triazines; Triazoles; Tubulin; Tubulin Modulators

2014
Evaluation of Pharmacokinetic Interactions Between Lesinurad, a New Selective Urate Reabsorption Inhibitor, and Commonly Used Drugs for Gout Treatment.
    Clinical pharmacology in drug development, 2017, Volume: 6, Issue:4

    Topics: Adult; Aged; Aged, 80 and over; Colchicine; Drug Administration Schedule; Drug Interactions; Female; Gout Suppressants; Humans; Hyperuricemia; Indomethacin; Male; Middle Aged; Naproxen; Thioglycolates; Treatment Outcome; Triazoles; Uricosuric Agents; Young Adult

2017
Colchicine metallocenyl bioconjugates showing high antiproliferative activities against cancer cell lines.
    Dalton transactions (Cambridge, England : 2003), 2017, Dec-12, Volume: 46, Issue:48

    Topics: Antineoplastic Agents; Apoptosis; Cell Proliferation; Colchicine; Ferrous Compounds; HCT116 Cells; Humans; Metallocenes; Mitosis; Protein Multimerization; Protein Structure, Quaternary; Reactive Oxygen Species; Triazoles; Tubulin

2017
Design, Synthesis and Cytotoxic Evaluation of Novel Chalcone Derivatives Bearing Triazolo[4,3-a]-quinoxaline Moieties as Potent Anticancer Agents with Dual EGFR Kinase and Tubulin Polymerization Inhibitory Effects.
    Molecules (Basel, Switzerland), 2017, Dec-27, Volume: 23, Issue:1

    Topics: Antineoplastic Agents; Apoptosis; Cell Line, Tumor; Cell Proliferation; Cell Survival; Chalcone; Colchicine; Drug Design; ErbB Receptors; Humans; Magnetic Resonance Spectroscopy; Molecular Docking Simulation; Molecular Structure; Protein Kinase Inhibitors; Quinoxalines; Spectrometry, Mass, Electrospray Ionization; Structure-Activity Relationship; Triazoles; Tubulin; Tubulin Modulators

2017
3-Aryl/Heteroaryl-5-amino-1-(3',4',5'-trimethoxybenzoyl)-1,2,4-triazoles as antimicrotubule agents. Design, synthesis, antiproliferative activity and inhibition of tubulin polymerization.
    Bioorganic chemistry, 2018, Volume: 80

    Topics: Apoptosis; Binding Sites; Cell Line, Tumor; Cell Proliferation; Colchicine; Drug Design; Drug Screening Assays, Antitumor; G2 Phase Cell Cycle Checkpoints; Humans; M Phase Cell Cycle Checkpoints; Molecular Dynamics Simulation; Protein Binding; Protein Structure, Tertiary; Structure-Activity Relationship; Thermodynamics; Triazoles; Tubulin; Tubulin Modulators

2018
Molecular diversity of trimethoxyphenyl-1,2,3-triazole hybrids as novel colchicine site tubulin polymerization inhibitors.
    European journal of medicinal chemistry, 2019, Mar-01, Volume: 165

    Topics: Antineoplastic Agents; Apoptosis; Cell Cycle Checkpoints; Cell Line, Tumor; Cell Proliferation; Colchicine; Drug Design; Drug Screening Assays, Antitumor; Humans; Polymerization; Structure-Activity Relationship; Triazoles; Tubulin

2019
Design, synthesis and biological evaluation of flexible and rigid analogs of 4H-1,2,4-triazoles bearing 3,4,5-trimethoxyphenyl moiety as new antiproliferative agents.
    Bioorganic chemistry, 2019, Volume: 93

    Topics: Animals; Antineoplastic Agents; Apoptosis; Binding Sites; Cell Line, Tumor; Cell Proliferation; Colchicine; Drug Design; Drug Screening Assays, Antitumor; Humans; Kinetics; Mice; Molecular Docking Simulation; Protein Binding; Protein Structure, Tertiary; Structure-Activity Relationship; Triazoles; Tubulin; Tubulin Modulators

2019
Design, synthesis, and biological screening of a series of 4'-fluoro-benzotriazole-acrylonitrile derivatives as microtubule-destabilising agents (MDAs).
    Journal of enzyme inhibition and medicinal chemistry, 2022, Volume: 37, Issue:1

    Topics: Acrylonitrile; Antineoplastic Agents; Cell Line, Tumor; Cell Proliferation; Colchicine; Drug Screening Assays, Antitumor; HeLa Cells; Humans; Ligands; Microtubules; Molecular Docking Simulation; Structure-Activity Relationship; Triazoles; Tubulin; Tubulin Modulators

2022
Discovery of 6-aryl-2-(3,4,5-trimethoxyphenyl)thiazole[3,2-b][1,2,4]triazoles as potent tubulin polymerization inhibitors.
    European journal of medicinal chemistry, 2023, Aug-05, Volume: 256

    Topics: Animals; Antineoplastic Agents; Cell Line, Tumor; Cell Proliferation; Colchicine; Drug Screening Assays, Antitumor; Humans; Mice; Molecular Structure; Polymerization; Structure-Activity Relationship; Thiazoles; Triazoles; Tubulin; Tubulin Modulators

2023