Page last updated: 2024-08-24

triazoles and chalcone

triazoles has been researched along with chalcone in 32 studies

Research

Studies (32)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's20 (62.50)24.3611
2020's12 (37.50)2.80

Authors

AuthorsStudies
Chibale, K; Gut, J; Hans, RH; Rosenthal, PJ1
Chibale, K; Egan, TJ; Guantai, EM; Gut, J; Ncokazi, K; Rosenthal, PJ; Smith, PJ1
Bedi, PM; Kaur, T; Kumar, V; Mahajan, MP; Raj, R; Saxena, AK; Singh, P1
Biot, C; Guérardel, Y; Kremer, L; Kumar, K; Kumar, V; Singh, P1
Biot, C; Carrère-Kremer, S; Guérardel, Y; Kremer, L; Kumar, K; Kumar, V1
Mandi, P; Nantasenamat, C; Pingaew, R; Prachayasittikul, S; Prachayasittikul, V; Ruchirawat, S; Saekee, A1
Alam, S; Arigari, NK; Chinde, S; Chinthala, Y; Domatti, AK; Grover, P; Jonnala, KK; K V N S, S; Khan, F; Thakur, S; Tirunagari, S; Tiwari, A1
Hong, G; Liu, T; Mao, L; Yang, X; Zhao, L1
El Sayed Aly, MR; Mohamed, MA; Saad, HA1
Agarwal, A; Agarwal, D; Awasthi, SK; Gupta, RD; Kant, R; Kumar, D; Tilak, R1
Gut, J; Kumar, V; Rosenthal, PJ; Singh, A1
Biot, C; Dupont, C; Kremer, L; Kumar, K; Kumar, V; Singh, A; Viljoen, A1
Bhushan, S; Guru, SK; Jaglan, S; Kumar, A; Lal, K; Yadav, P1
Ahmed, HEA; Alswah, M; Bayoumi, AH; Elgamal, K; Elmorsy, A; Ihmaid, S1
Kumar, A; Lal, K; Paul, AK; Yadav, P1
Cardona-G, W; Herrera-R, A; Yepes, AF1
Kumar, A; Kumar, L; Kumar, R; Lal, K; Paul, AK; Yadav, P1
Ali, I; Gomha, SM; Khalil, KD; Riyadh, SM1
Jana, K; Manna, T; Misra, AK; Pal, K1
Csámpai, A; Dembo, A; Duró, C; Jernei, T; Kőhidai, L; Lajkó, E; Schlosser, G; Takács, A1
Bantu, R; Jain, N; Janardhan, S; Nagarapu, L; Vanaparthi, S1
Abdel-Aziz, M; Abdelhamid, D; Fujita, M; Gouda, AM; Hassan, HA; Mohassab, AM; Otsuka, M; Tateishi, H; Youssif, BGM1
Aboelnaga, A; Elabbady, S; Fahim, AM; Nassar, E; Soror, S1
Cidade, H; Correia-da-Silva, M; Pereira, D; Pinto, M1
Abulkhair, HS; Fayed, EA; Husseiny, EM; Othman, EM1
Abbas, SH; Abd El-Hafeez, AA; Abourehab, MAS; Abuo-Rahma, GEA; Alhaj-Suliman, SO; Ebeid, K; Ghosh, P; Hayallah, AM; Mekkawy, AI; Mohammed, HHH; Salem, AK; Wafa, EI1
Kamra, N; Kumar, D; Rani, S; Sangwan, PL; Singh, A; Singh, SK; Singh, V; Thakral, S1
Maghraby, MT; Salem, OIA; Sheha, MM; Youssif, BGM1
Cidade, H; Correia-da-Silva, M; Durães, F; Freitas-da-Silva, J; Martins-da-Costa, P; Pereira, D; Pinto, E; Pinto, M; Sousa, E; Spengler, G; Szemerédi, N1
Ding, Q; Jiang, F; Lu, Y; Wang, H; Xia, Z; Zhang, C1
Gong, Z; Su, Q; Tian, Z; Xu, B1
Csala, M; Csámpai, A; Duró, C; Gurbi, B; Móra, I; Murányi, J; Németh, K; Simon, J; Varga, A1

Reviews

2 review(s) available for triazoles and chalcone

ArticleYear
Hybrid Molecules: Promising Compounds for the Development of New Treatments Against Leishmaniasis and Chagas Disease.
    Current medicinal chemistry, 2018, Volume: 25, Issue:30

    Topics: Antiprotozoal Agents; Chagas Disease; Chalcone; Humans; Hydrazones; Leishmaniasis; Pentamidine; Quinolines; Terpenes; Triazoles

2018
Recent Advances in Bioactive Flavonoid Hybrids Linked by 1,2,3-Triazole Ring Obtained by Click Chemistry.
    Molecules (Basel, Switzerland), 2021, Dec-30, Volume: 27, Issue:1

    Topics: Anti-Inflammatory Agents; Antineoplastic Agents; Antioxidants; Chalcone; Chemistry Techniques, Synthetic; Click Chemistry; Cycloaddition Reaction; Dimerization; Dose-Response Relationship, Drug; Flavonoids; Molecular Structure; Neuroprotective Agents; Structure-Activity Relationship; Triazoles

2021

Other Studies

30 other study(ies) available for triazoles and chalcone

ArticleYear
Comparison of the antiplasmodial and falcipain-2 inhibitory activity of beta-amino alcohol thiolactone-chalcone and isatin-chalcone hybrids.
    Bioorganic & medicinal chemistry letters, 2010, Apr-01, Volume: 20, Issue:7

    Topics: Antimalarials; Chalcone; Cysteine Endopeptidases; Cysteine Proteinase Inhibitors; Humans; Isatin; Lactones; Malaria, Falciparum; Plasmodium falciparum; Triazoles

2010
Design, synthesis and in vitro antimalarial evaluation of triazole-linked chalcone and dienone hybrid compounds.
    Bioorganic & medicinal chemistry, 2010, Dec-01, Volume: 18, Issue:23

    Topics: Alkynes; Aminoquinolines; Animals; Antimalarials; Azides; Catalysis; Chalcone; Chalcones; Copper; Drug Design; Hemin; Nucleosides; Plasmodium falciparum; Quinolines; Structure-Activity Relationship; Triazoles

2010
1,2,3-Triazole tethered β-lactam-chalcone bifunctional hybrids: synthesis and anticancer evaluation.
    European journal of medicinal chemistry, 2012, Volume: 47, Issue:1

    Topics: Antineoplastic Agents; beta-Lactams; Cell Line, Tumor; Cell Proliferation; Chalcone; Humans; Inhibitory Concentration 50; Triazoles

2012
Synthesis and in vitro anti-tubercular evaluation of 1,2,3-triazole tethered β-lactam-ferrocene and β-lactam-ferrocenylchalcone chimeric scaffolds.
    Dalton transactions (Cambridge, England : 2003), 2012, May-21, Volume: 41, Issue:19

    Topics: Antitubercular Agents; beta-Lactams; Chalcone; Chemistry Techniques, Synthetic; Ferrous Compounds; Metallocenes; Microbial Sensitivity Tests; Mycobacterium tuberculosis; Triazoles

2012
Azide-alkyne cycloaddition en route towards 1H-1,2,3-triazole-tethered β-lactam-ferrocene and β-lactam-ferrocenylchalcone conjugates: synthesis and in vitro anti-tubercular evaluation.
    Dalton transactions (Cambridge, England : 2003), 2013, Feb-07, Volume: 42, Issue:5

    Topics: Alkynes; Antitubercular Agents; Azides; beta-Lactams; Chalcone; Copper; Cycloaddition Reaction; Ferrous Compounds; Metallocenes; Microbial Sensitivity Tests; Mycobacterium tuberculosis; Structure-Activity Relationship; Triazoles

2013
Synthesis, biological evaluation and molecular docking of novel chalcone-coumarin hybrids as anticancer and antimalarial agents.
    European journal of medicinal chemistry, 2014, Oct-06, Volume: 85

    Topics: Antimalarials; Antineoplastic Agents; Cell Line, Tumor; Chalcone; Chemistry Techniques, Synthetic; Coumarins; Cysteine Endopeptidases; Humans; Molecular Docking Simulation; Plasmodium falciparum; Protein Conformation; Triazoles; Tubulin

2014
Synthesis, docking and ADMET studies of novel chalcone triazoles for anti-cancer and anti-diabetic activity.
    European journal of medicinal chemistry, 2015, Mar-26, Volume: 93

    Topics: alpha-Glucosidases; Animals; Antigens, Neoplasm; Antineoplastic Agents; Cell Line, Tumor; Cell Proliferation; Chalcone; Chemistry Techniques, Synthetic; DNA Topoisomerases, Type II; DNA-Binding Proteins; Glycoside Hydrolase Inhibitors; Humans; Hypoglycemic Agents; Molecular Docking Simulation; Protein Conformation; Rats; Structure-Activity Relationship; Tissue Distribution; Triazoles

2015
Design, synthesis and anticancer activity of matrine-1H-1,2,3-triazole-chalcone conjugates.
    Bioorganic & medicinal chemistry letters, 2015, Jun-15, Volume: 25, Issue:12

    Topics: Alkaloids; Animals; Antineoplastic Agents; Apoptosis; Cell Line, Tumor; Chalcone; Drug Design; Drug Screening Assays, Antitumor; Fluorouracil; HeLa Cells; Humans; Male; Matrines; MCF-7 Cells; Mice; Mice, Inbred BALB C; Mice, Nude; NIH 3T3 Cells; Quinolizines; Structure-Activity Relationship; Transplantation, Heterologous; Triazoles

2015
Click reaction based synthesis, antimicrobial, and cytotoxic activities of new 1,2,3-triazoles.
    Bioorganic & medicinal chemistry letters, 2015, Jul-15, Volume: 25, Issue:14

    Topics: Anti-Infective Agents; Aspergillus flavus; Bacteria; Candida albicans; Cell Line, Tumor; Cell Survival; Chalcone; Click Chemistry; Escherichia coli; Fungi; Humans; Microbial Sensitivity Tests; Quinolines; Staphylococcus aureus; Triazoles

2015
Synthesis of newer 1,2,3-triazole linked chalcone and flavone hybrid compounds and evaluation of their antimicrobial and cytotoxic activities.
    European journal of medicinal chemistry, 2016, May-04, Volume: 113

    Topics: Anti-Bacterial Agents; Antifungal Agents; Antimalarials; Bacteria; Cell Line, Tumor; Chalcone; Dose-Response Relationship, Drug; Flavones; Fungi; Humans; Microbial Sensitivity Tests; Molecular Structure; Parasitic Sensitivity Tests; Plasmodium falciparum; Structure-Activity Relationship; Triazoles

2016
4-Aminoquinoline-ferrocenyl-chalcone conjugates: Synthesis and anti-plasmodial evaluation.
    European journal of medicinal chemistry, 2017, Jan-05, Volume: 125

    Topics: Aminoquinolines; Animals; Antimalarials; Antiparasitic Agents; Chalcone; Dose-Response Relationship, Drug; Drug Resistance, Microbial; Ferrous Compounds; Humans; Metallocenes; Parasitic Sensitivity Tests; Plasmodium; Plasmodium falciparum; Structure-Activity Relationship; Triazoles

2017
1H-1,2,3-triazole-tethered uracil-ferrocene and uracil-ferrocenylchalcone conjugates: Synthesis and antitubercular evaluation.
    Chemical biology & drug design, 2017, Volume: 89, Issue:6

    Topics: Antitubercular Agents; Catalysis; Cell Survival; Chalcone; Copper; Ferrous Compounds; HeLa Cells; Humans; Metallocenes; Microbial Sensitivity Tests; Mycobacterium tuberculosis; Structure-Activity Relationship; Triazoles; Uracil

2017
Green synthesis and anticancer potential of chalcone linked-1,2,3-triazoles.
    European journal of medicinal chemistry, 2017, Jan-27, Volume: 126

    Topics: Antineoplastic Agents; Apoptosis; Cell Line, Tumor; Cell Proliferation; Chalcone; Chemistry Techniques, Synthetic; Dose-Response Relationship, Drug; Drug Design; Drug Screening Assays, Antitumor; G2 Phase Cell Cycle Checkpoints; Green Chemistry Technology; Humans; M Phase Cell Cycle Checkpoints; Membrane Potential, Mitochondrial; Structure-Activity Relationship; Triazoles; Water

2017
Design, Synthesis and Cytotoxic Evaluation of Novel Chalcone Derivatives Bearing Triazolo[4,3-a]-quinoxaline Moieties as Potent Anticancer Agents with Dual EGFR Kinase and Tubulin Polymerization Inhibitory Effects.
    Molecules (Basel, Switzerland), 2017, Dec-27, Volume: 23, Issue:1

    Topics: Antineoplastic Agents; Apoptosis; Cell Line, Tumor; Cell Proliferation; Cell Survival; Chalcone; Colchicine; Drug Design; ErbB Receptors; Humans; Magnetic Resonance Spectroscopy; Molecular Docking Simulation; Molecular Structure; Protein Kinase Inhibitors; Quinoxalines; Spectrometry, Mass, Electrospray Ionization; Structure-Activity Relationship; Triazoles; Tubulin; Tubulin Modulators

2017
Design, synthesis, characterization, antimicrobial evaluation and molecular modeling studies of some dehydroacetic acid-chalcone-1,2,3-triazole hybrids.
    Bioorganic chemistry, 2018, Volume: 77

    Topics: Anti-Bacterial Agents; Antifungal Agents; Aspergillus niger; Bacillus subtilis; Candida albicans; Chalcone; Dose-Response Relationship, Drug; Drug Design; Escherichia coli; Microbial Sensitivity Tests; Models, Molecular; Molecular Structure; Pseudomonas aeruginosa; Pyrones; Staphylococcus epidermidis; Structure-Activity Relationship; Triazoles

2018
Synthesis, crystal structure and antimicrobial potential of some fluorinated chalcone-1,2,3-triazole conjugates.
    European journal of medicinal chemistry, 2018, Jul-15, Volume: 155

    Topics: Anti-Bacterial Agents; Antifungal Agents; Aspergillus niger; Bacillus subtilis; Candida albicans; Chalcone; Crystallography, X-Ray; Dose-Response Relationship, Drug; Escherichia coli; Halogenation; Microbial Sensitivity Tests; Models, Molecular; Molecular Structure; Pseudomonas aeruginosa; Staphylococcus epidermidis; Structure-Activity Relationship; Triazoles

2018
Synthesis, characterization and application of copper oxide chitosan nanocomposite for green regioselective synthesis of [1,2,3]triazoles.
    International journal of biological macromolecules, 2019, Jun-01, Volume: 130

    Topics: Azides; Catalysis; Chalcone; Chitosan; Copper; Cycloaddition Reaction; Green Chemistry Technology; Models, Molecular; Molecular Conformation; Nanocomposites; Triazoles

2019
Anti-cancer potential of novel glycosylated 1,4-substituted triazolylchalcone derivatives.
    Bioorganic & medicinal chemistry letters, 2019, 10-01, Volume: 29, Issue:19

    Topics: Antineoplastic Agents; Breast Neoplasms; Cell Proliferation; Chalcone; Click Chemistry; Cycloaddition Reaction; Drug Screening Assays, Antitumor; Female; Glycosylation; Humans; Molecular Structure; Structure-Activity Relationship; Triazoles

2019
Synthesis, Structure and In Vitro Cytotoxic Activity of Novel Cinchona-Chalcone Hybrids with 1,4-Disubstituted- and 1,5-Disubstituted 1,2,3-Triazole Linkers.
    Molecules (Basel, Switzerland), 2019, Nov-11, Volume: 24, Issue:22

    Topics: Antineoplastic Agents; Cell Line, Tumor; Cell Proliferation; Chalcone; Chemistry Techniques, Synthetic; Cinchona; Humans; Inhibitory Concentration 50; Models, Molecular; Molecular Conformation; Molecular Structure; Structure-Activity Relationship; Triazoles

2019
Synthesis and anti-proliferative activity of a novel 1,2,3-triazole tethered chalcone acetamide derivatives.
    Bioorganic & medicinal chemistry letters, 2020, 08-15, Volume: 30, Issue:16

    Topics: Acetamides; Antineoplastic Agents; Cell Line, Tumor; Cell Proliferation; Chalcone; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; Humans; Molecular Structure; Structure-Activity Relationship; Triazoles

2020
Design and synthesis of novel quinoline/chalcone/1,2,4-triazole hybrids as potent antiproliferative agent targeting EGFR and BRAF
    Bioorganic chemistry, 2021, Volume: 106

    Topics: Antineoplastic Agents; Apoptosis; Cell Line; Cell Proliferation; Chalcone; Dose-Response Relationship, Drug; Drug Design; Drug Screening Assays, Antitumor; ErbB Receptors; Humans; Molecular Structure; Protein Kinase Inhibitors; Proto-Oncogene Proteins B-raf; Quinolines; Structure-Activity Relationship; Triazoles

2021
Synthesis, antimicrobial activities, docking studies and computational calculations of new bis-1,4-phenylene -1
    Journal of biomolecular structure & dynamics, 2022, Volume: 40, Issue:12

    Topics: Anti-Infective Agents; Chalcone; Microbial Sensitivity Tests; Structure-Activity Relationship; Triazoles; Ultrasonics

2022
Apoptosis induction, PARP-1 inhibition, and cell cycle analysis of leukemia cancer cells treated with novel synthetic 1,2,3-triazole-chalcone conjugates.
    Bioorganic chemistry, 2022, Volume: 123

    Topics: Antineoplastic Agents; Apoptosis; Cell Cycle; Cell Line, Tumor; Cell Proliferation; Chalcone; Chalcones; Drug Screening Assays, Antitumor; Humans; Leukemia; Molecular Docking Simulation; Molecular Structure; Poly(ADP-ribose) Polymerase Inhibitors; Structure-Activity Relationship; Triazoles

2022
New 1,2,3-triazole linked ciprofloxacin-chalcones induce DNA damage by inhibiting human topoisomerase I& II and tubulin polymerization.
    Journal of enzyme inhibition and medicinal chemistry, 2022, Volume: 37, Issue:1

    Topics: Antineoplastic Agents; Caco-2 Cells; Cell Line, Tumor; Cell Proliferation; Chalcone; Chalcones; Ciprofloxacin; DNA Damage; DNA Topoisomerases, Type I; DNA Topoisomerases, Type II; Doxorubicin; Drug Screening Assays, Antitumor; Humans; Molecular Structure; Polymerization; Structure-Activity Relationship; Triazoles; Tubulin

2022
Synthesis, Biological Activity and Molecular Docking Studies of Heterocyclic Chalcones.
    Chemistry & biodiversity, 2022, Volume: 19, Issue:9

    Topics: Aldehydes; Anti-Infective Agents; Antineoplastic Agents; Candida albicans; Chalcone; Chalcones; Imidazoles; Indoles; Molecular Docking Simulation; Molecular Structure; Pyrazoles; Staphylococcus aureus; Structure-Activity Relationship; Thiophenes; Triazoles

2022
Design, synthesis, and modelling study of new 1,2,3-triazole/chalcone hybrids with antiproliferative action as epidermal growth factor receptor inhibitors.
    Chemical biology & drug design, 2023, Volume: 101, Issue:3

    Topics: Antineoplastic Agents; Cell Line, Tumor; Cell Proliferation; Chalcone; Chalcones; Doxorubicin; Drug Screening Assays, Antitumor; ErbB Receptors; Molecular Docking Simulation; Molecular Structure; Protein Kinase Inhibitors; Proto-Oncogene Proteins B-raf; Structure-Activity Relationship; Triazoles

2023
New Chalcone-Triazole Hybrids with Promising Antimicrobial Activity in Multidrug Resistance Strains.
    International journal of molecular sciences, 2022, Nov-18, Volume: 23, Issue:22

    Topics: Anti-Bacterial Agents; Anti-Infective Agents; Bacteria; Chalcone; Chalcones; Drug Resistance, Multiple; Humans; Methicillin-Resistant Staphylococcus aureus; Salmonella typhimurium; Staphylococcal Infections; Triazoles

2022
Novel Chalcone-Phenazine Hybrids Induced Ferroptosis in U87-MG Cells through Activating Ferritinophagy.
    Chemistry & biodiversity, 2023, Volume: 20, Issue:2

    Topics: Autophagy; Chalcone; Chalcones; Ferroptosis; Phenazines; Triazoles

2023
Design and development of novel 1,2,3-triazole chalcone derivatives as potential anti-osteosarcoma agents
    Acta pharmaceutica (Zagreb, Croatia), 2022, Sep-01, Volume: 72, Issue:3

    Topics: Adolescent; Antineoplastic Agents; Apoptosis; Bone Neoplasms; Cell Line, Tumor; Cell Proliferation; Chalcone; Chalcones; Child; Drug Screening Assays, Antitumor; Humans; Osteosarcoma; Phosphatidylinositol 3-Kinases; Proto-Oncogene Proteins c-akt; Structure-Activity Relationship; TOR Serine-Threonine Kinases; Triazoles

2022
Novel Erlotinib-Chalcone Hybrids Diminish Resistance in Head and Neck Cancer by Inducing Multiple Cell Death Mechanisms.
    International journal of molecular sciences, 2023, Feb-09, Volume: 24, Issue:4

    Topics: Antineoplastic Agents; Apoptosis; Cell Death; Cell Line, Tumor; Chalcone; Chalcones; Erlotinib Hydrochloride; Head and Neck Neoplasms; Humans; Necrosis; Squamous Cell Carcinoma of Head and Neck; Triazoles

2023