Page last updated: 2024-08-24

triazoles and cevipabulin

triazoles has been researched along with cevipabulin in 8 studies

Research

Studies (8)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's4 (50.00)29.6817
2010's3 (37.50)24.3611
2020's1 (12.50)2.80

Authors

AuthorsStudies
Ayral-Kaloustian, S; Beyer, C; Hernandez, R; Nguyen, T; Zhang, N1
Ayral-Kaloustian, S; Beyer, CF; Discafani, C; Gibbons, JJ; Hernandez, R; Lucas, J; Nguyen, T; Vitale, D; Zhang, N1
Ayral-Kaloustian, S; Beyer, CF; Gibbons, JJ; Hernandez, R; Nguyen, T; Vitale, D; Zhang, N1
Ayral-Kaloustian, S; Beyer, C; Zhang, N1
Arnold, SM; Bukowski, RM; Cooper, W; Gauthier, E; Lockhart, AC; Rothenberg, ML; Wang, KK; Wang-Gillam, A1
Ballatore, C; Brunden, KR; Cornec, AS; Crowe, A; James, M; Kovalevich, J; Lee, VM; Smith, AB; Trojanowski, JQ; Yao, Y1
Ishihara, T; Kakugo, A; Konagaya, A; Nasrin, SR; Rashedul Kabir, AM; Sada, K1
Alle, T; Ballatore, C; Brunden, KR; Lee, VM; Maimaiti, S; Nzou, G; Trojanowski, JQ; Tsering, W; Yao, Y1

Reviews

1 review(s) available for triazoles and cevipabulin

ArticleYear
Cevipabulin (TTI-237): preclinical and clinical results for a novel antimicrotubule agent.
    Methods and findings in experimental and clinical pharmacology, 2009, Volume: 31, Issue:7

    Topics: Animals; Antimitotic Agents; Clinical Trials as Topic; Clinical Trials, Phase I as Topic; Drug Evaluation, Preclinical; Humans; Hydrocarbons, Halogenated; Mice; Microtubules; Neoplasms; Rats; Triazoles

2009

Trials

1 trial(s) available for triazoles and cevipabulin

ArticleYear
A phase I dose escalation study of TTI-237 in patients with advanced malignant solid tumors.
    Investigational new drugs, 2012, Volume: 30, Issue:1

    Topics: Adult; Aged; Antineoplastic Agents; Area Under Curve; Drug Administration Schedule; Early Termination of Clinical Trials; Female; Half-Life; Humans; Hydrocarbons, Halogenated; Infusions, Intravenous; Male; Maximum Tolerated Dose; Middle Aged; Neoplasms; Treatment Outcome; Triazoles; Tubulin Modulators

2012

Other Studies

6 other study(ies) available for triazoles and cevipabulin

ArticleYear
2-cyanoaminopyrimidines as a class of antitumor agents that promote tubulin polymerization.
    Bioorganic & medicinal chemistry letters, 2007, Jun-01, Volume: 17, Issue:11

    Topics: Antineoplastic Agents; Cell Line, Tumor; Cell Proliferation; Humans; Hydrocarbons, Halogenated; Pyrimidines; Structure-Activity Relationship; Triazoles; Tubulin

2007
TTI-237: a novel microtubule-active compound with in vivo antitumor activity.
    Cancer research, 2008, Apr-01, Volume: 68, Issue:7

    Topics: Animals; Antineoplastic Agents; Carcinoma, Squamous Cell; Cell Line, Tumor; Drug Screening Assays, Antitumor; Female; HeLa Cells; Humans; Hydrocarbons, Halogenated; Mice; Mice, Nude; Microtubules; Triazoles; Tubulin; Xenograft Model Antitumor Assays

2008
The microtubule-active antitumor compound TTI-237 has both paclitaxel-like and vincristine-like properties.
    Cancer chemotherapy and pharmacology, 2009, Volume: 64, Issue:4

    Topics: Antineoplastic Agents; Biopolymers; Cold Temperature; Flow Cytometry; Guanosine Triphosphate; HeLa Cells; Humans; Hydrocarbons, Halogenated; Microtubules; Paclitaxel; Radioligand Assay; Triazoles; Tubulin; Vincristine

2009
Characterization of Brain-Penetrant Pyrimidine-Containing Molecules with Differential Microtubule-Stabilizing Activities Developed as Potential Therapeutic Agents for Alzheimer's Disease and Related Tauopathies.
    The Journal of pharmacology and experimental therapeutics, 2016, Volume: 357, Issue:2

    Topics: Alzheimer Disease; Animals; Biological Availability; Blood-Brain Barrier; Cell Division; Dose-Response Relationship, Drug; Female; Hydrocarbons, Halogenated; Male; Mice; Microtubules; Neurons; Proteasome Endopeptidase Complex; Pyrimidines; tau Proteins; Tauopathies; Triazoles; Tubulin

2016
Stabilization of microtubules by cevipabulin.
    Biochemical and biophysical research communications, 2019, 08-27, Volume: 516, Issue:3

    Topics: Animals; Hydrocarbons, Halogenated; Microscopy, Fluorescence; Microtubules; Molecular Docking Simulation; Molecular Structure; Nanotechnology; Paclitaxel; Protein Stability; Swine; Time-Lapse Imaging; Triazoles; Tubulin

2019
Correction of microtubule defects within Aβ plaque-associated dystrophic axons results in lowered Aβ release and plaque deposition.
    Alzheimer's & dementia : the journal of the Alzheimer's Association, 2020, Volume: 16, Issue:10

    Topics: Amyloid beta-Peptides; Animals; Axons; Brain; Disease Models, Animal; Female; Humans; Hydrocarbons, Halogenated; Male; Mice; Mice, Transgenic; Microtubules; Plaque, Amyloid; Triazoles

2020