triazoles has been researched along with cep 33779 in 11 studies
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 0 (0.00) | 18.7374 |
1990's | 0 (0.00) | 18.2507 |
2000's | 0 (0.00) | 29.6817 |
2010's | 10 (90.91) | 24.3611 |
2020's | 1 (9.09) | 2.80 |
Authors | Studies |
---|---|
Albom, MS; Angeles, TS; Ator, MA; Dobrzanski, P; Dorsey, BD; Dugan, BJ; Gingrich, DE; Lu, LD; Ruggeri, BA; Seavey, MM; Serdikoff, C; Stump, KL | 1 |
Albom, MS; Angeles, TS; Ator, MA; Dobrzanski, P; Dorsey, BD; Dugan, BJ; Gingrich, DE; Lu, LD; Mason, JL; Ruggeri, BA; Seavey, MM; Serdikoff, C; Stump, KL; Wallace, NH | 1 |
Dobrzanski, P; Hockeimer, W; Lu, LD; O'Kane, TM; Ruggeri, BA; Seavey, MM; Stump, KL; Wallace, NH | 1 |
Putterman, C; Tagoe, C | 1 |
Aimone, LD; Albom, MS; Angeles, TS; Ator, MA; Curry, MA; Dobrzanski, P; Dorsey, BD; Dugan, BJ; Gingrich, DE; Huang, Z; Jan, M; Mason, JL; Mesaros, EF; Meyer, SL; Milkiewicz, KL; Ruggeri, BA; Serdikoff, C; Wells-Knecht, KJ; Zulli, AL | 1 |
Chen, LK; Chen, WQ; Chen, ZS; Fu, LW; Huang, ZC; Talele, TT; Tang, SJ; To, KK; Wang, F; Wang, XK; Zhang, YK | 1 |
Li, R; Luo, H; Wu, C; Xu, M; Zhang, X | 1 |
Cheon, JH; Kim, HS; Kim, KS; Kim, M; Yadav, DK; Yoon, S | 1 |
Cheon, JH; Kim, HS; Kim, JY; Lee, BM; Yoon, S | 1 |
Boran, A; Chen, Y; Gallo, J; Goldfarb, J; Hu, Y; Iyengar, R; Jayaraman, G; Li, L; Mariottini, C; Tavassoly, I; Tolentino, RE; Zhao, S | 1 |
Chang, Y; Chen, J; Christiano, AM; Dai, Z | 1 |
11 other study(ies) available for triazoles and cep 33779
Article | Year |
---|---|
A highly selective, orally active inhibitor of Janus kinase 2, CEP-33779, ablates disease in two mouse models of rheumatoid arthritis.
Topics: Administration, Oral; Animals; Anti-Inflammatory Agents; Arthritis, Experimental; Arthritis, Rheumatoid; Blotting, Western; Disease Models, Animal; Enzyme Inhibitors; Enzyme-Linked Immunosorbent Assay; Female; Janus Kinase 2; Mice; Mice, Inbred DBA; Pyridines; Triazoles | 2011 |
Depletion of autoreactive plasma cells and treatment of lupus nephritis in mice using CEP-33779, a novel, orally active, selective inhibitor of JAK2.
Topics: Administration, Oral; Animals; Antibodies, Antinuclear; Autoimmunity; Cell Separation; Cytokines; Disease Models, Animal; Enzyme Inhibitors; Enzyme-Linked Immunosorbent Assay; Female; Flow Cytometry; Janus Kinase 2; Lupus Nephritis; Mice; Mice, Inbred MRL lpr; Plasma Cells; Pyridines; Triazoles | 2011 |
Therapeutic efficacy of CEP-33779, a novel selective JAK2 inhibitor, in a mouse model of colitis-induced colorectal cancer.
Topics: Animals; Cell Line, Tumor; Colitis; Colorectal Neoplasms; Disease Models, Animal; Female; Humans; Janus Kinase 2; Mice; Mice, Inbred BALB C; Phosphorylation; Protein Kinase Inhibitors; Pyridines; Triazoles | 2012 |
JAK2 inhibition in murine systemic lupus erythematosus.
Topics: Animals; Disease Models, Animal; Humans; Interleukin-6; Janus Kinase 2; Kidney; Lupus Erythematosus, Systemic; Lupus Nephritis; Mice; Plasma Cells; Pyridines; Signal Transduction; Treatment Outcome; Triazoles | 2012 |
A selective, orally bioavailable 1,2,4-triazolo[1,5-a]pyridine-based inhibitor of Janus kinase 2 for use in anticancer therapy: discovery of CEP-33779.
Topics: Administration, Oral; Animals; Antineoplastic Agents; Biological Availability; Cell Line; Crystallography, X-Ray; Dogs; Humans; Janus Kinase 2; Mice; Mice, Nude; Microsomes, Liver; Models, Molecular; Molecular Structure; Pyridines; Rats; Structure-Activity Relationship; Triazoles; Xenograft Model Antitumor Assays | 2012 |
CEP-33779 antagonizes ATP-binding cassette subfamily B member 1 mediated multidrug resistance by inhibiting its transport function.
Topics: Animals; Antineoplastic Agents; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 1; Cell Line, Tumor; Dose-Response Relationship, Drug; Doxorubicin; Drug Resistance, Neoplasm; Heterografts; Humans; Mice; Mice, Nude; Molecular Structure; Neoplasms, Experimental; Pyridines; Real-Time Polymerase Chain Reaction; Rhodamine 123; Topotecan; Triazoles | 2014 |
JAK2 inhibitor CEP-33779 prevents mouse oocyte maturation
Topics: Animals; Female; Janus Kinase 2; Meiosis; Mice; Oocytes; Pyridines; Triazoles | 2017 |
The JAK2 inhibitors CEP-33779 and NVP-BSK805 have high P-gp inhibitory activity and sensitize drug-resistant cancer cells to vincristine.
Topics: Antineoplastic Agents; ATP Binding Cassette Transporter, Subfamily B, Member 1; Cell Proliferation; Dose-Response Relationship, Drug; Drug Resistance, Neoplasm; Drug Screening Assays, Antitumor; Humans; Janus Kinase 2; Protein Kinase Inhibitors; Pyridines; Quinoxalines; Structure-Activity Relationship; Triazoles; Tumor Cells, Cultured; Vincristine | 2017 |
P-gp Inhibition by XL019, a JAK2 Inhibitor, Increases Apoptosis of Vincristine-treated Resistant KBV20C Cells with Increased p21 and pH2AX Expression.
Topics: Antineoplastic Agents, Phytogenic; Apoptosis; ATP Binding Cassette Transporter, Subfamily B, Member 1; Blotting, Western; Cell Line, Tumor; Cell Survival; Cyclin-Dependent Kinase Inhibitor p21; Drug Resistance, Neoplasm; Drug Synergism; G2 Phase Cell Cycle Checkpoints; Histones; Humans; Janus Kinase 2; Phosphorylation; Proline; Pyridines; Pyrimidines; Triazoles; Vincristine | 2017 |
Genomic signatures defining responsiveness to allopurinol and combination therapy for lung cancer identified by systems therapeutics analyses.
Topics: Allopurinol; Animals; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Non-Small-Cell Lung; Cell Line, Tumor; Cell Survival; Drug Resistance, Neoplasm; Female; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Genomics; Humans; Janus Kinase 2; Lung Neoplasms; Mice, Nude; Phenotype; Protein Kinase Inhibitors; Pyridines; Systems Analysis; Triazoles; Xenograft Model Antitumor Assays | 2019 |
Selective inhibition of JAK3 signaling is sufficient to reverse alopecia areata.
Topics: Administration, Topical; Alopecia Areata; Animals; Azetidines; CD8-Positive T-Lymphocytes; Cytokines; Isonicotinic Acids; Janus Kinase 1; Janus Kinase 2; Janus Kinase 3; Macrophages; Mice, Inbred C3H; Nitriles; NK Cell Lectin-Like Receptor Subfamily K; Piperidines; Protein Kinase Inhibitors; Pyrazoles; Pyridines; Pyrimidines; Pyrroles; Triazoles | 2021 |