Page last updated: 2024-08-24

triazoles and camptothecin

triazoles has been researched along with camptothecin in 15 studies

Research

Studies (15)

TimeframeStudies, this research(%)All Research%
pre-19901 (6.67)18.7374
1990's1 (6.67)18.2507
2000's2 (13.33)29.6817
2010's9 (60.00)24.3611
2020's2 (13.33)2.80

Authors

AuthorsStudies
Brockman, RW1
Enomoto, K1
Pohjala, L; Samanta, SK; Tammela, P; Vuorela, P; Yli-Kauhaluoma, J1
Assaraf, YG; Bram, EE; Grimberg, M; Ifergan, I; Lemke, K; Skladanowski, A1
Kozłowska, E; Orzechowska, E; Staroń, K; Trzcińska-Danielewicz, J1
Acquaviva, J; Astsaturov, I; Bates, RC; Chimmanamada, D; He, S; Inoue, T; Jimenez, JP; Khazak, V; Ogawa, LS; Osman, S; Proia, DA; Sang, J; Sequeira, M; Smith, DL; Tatsuta, N; Ying, W; Zhang, C; Zhang, J1
Bosenberg, MW; Held, MA; Iyidogan, P; Langdon, CG; Levy, F; Mamillapalli, R; Platt, JT; Stern, DF; Theodosakis, N; Vuagniaux, G; Wang, S; Wiedemann, N1
Chen, S; Pan, M; Tong, Y; Zhang, L; Zhang, X1
Baryawno, N; Calero, R; Darabi, A; Dyberg, C; Einvik, C; Johnsen, JI; Kogner, P; Kool, M; Milosevic, J; Sandén, E; Siesjö, P; Sveinbjörnsson, B; Wickström, M1
Dong, G; Fang, K; Li, J; Liu, W; Miao, Z; Min, X; Sheng, C; Wu, Y; Xu, X; Yao, J; Yu, Z; Zhang, H; Zhang, W1
Basler, C; Benner, C; Bouvier, N; Bukreyev, A; Campisi, L; Chen, X; Edwards, M; Fenouil, R; García-Sastre, A; Heinz, S; Ho, JSY; Jin, J; Jordan, S; Lagda, AC; Marazzi, I; Martinez-Gil, L; Merad, M; Metreveli, G; Munoz-Fontela, C; Peralta, Z; Pietzsch, C; Rialdi, A; van Bakel, H; Weirauch, M; Zhao, N1
Bejrowska, A; Mazerska, Z; Mróz, A; Pawłowska, M1
Dong, S; He, J; Li, D; Li, L; Ni, P; Sun, Y; Zhang, M1
Chen, K; He, L; Hu, W; Lei, L; Li, Y; Lv, Z; Xie, X; Zhou, B; Zhou, Z1
Ghaedi, K; Majd, A; Miralaei, N; Peymani, M; Safaei, M1

Reviews

2 review(s) available for triazoles and camptothecin

ArticleYear
Biochemical aspects of drug combinations.
    Cancer chemotherapy reports. Part 2, 1974, Volume: 4, Issue:1

    Topics: Alkylating Agents; Animals; Antineoplastic Agents; Bleomycin; Camptothecin; Cell Division; Cytarabine; Deferoxamine; Diamines; DNA, Neoplasm; Doxorubicin; Drug Therapy, Combination; Leukemia L1210; Macromolecular Substances; Mice; Neoplasms; Neoplasms, Experimental; Nitrosourea Compounds; Purine Nucleotides; Ribonucleotide Reductases; Thioguanine; Triazoles

1974
[New drugs in metastatic breast cancer--1997].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1997, Volume: 24, Issue:13

    Topics: Antineoplastic Agents; Antineoplastic Agents, Phytogenic; Aromatase Inhibitors; Breast Neoplasms; Bridged-Ring Compounds; Camptothecin; Clinical Trials, Phase II as Topic; Clinical Trials, Phase III as Topic; Cyclophosphamide; Diphosphonates; Drug Resistance, Multiple; Female; Humans; Ibandronic Acid; Imidazoles; Letrozole; Nitriles; Tamoxifen; Taxoids; Triazoles; Zoledronic Acid

1997

Other Studies

13 other study(ies) available for triazoles and camptothecin

ArticleYear
Assessing the data quality in predictive toxicology using a panel of cell lines and cytotoxicity assays.
    Analytical biochemistry, 2007, Mar-15, Volume: 362, Issue:2

    Topics: Animals; Caco-2 Cells; Camptothecin; Cell Line; Cell Line, Tumor; Cell Survival; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Fluorouracil; Gramicidin; Humans; Inhibitory Concentration 50; Molecular Structure; Polymyxin B; Reproducibility of Results; Triazoles; Xenobiotics

2007
C421 allele-specific ABCG2 gene amplification confers resistance to the antitumor triazoloacridone C-1305 in human lung cancer cells.
    Biochemical pharmacology, 2007, Jun-30, Volume: 74, Issue:1

    Topics: Acridines; Aminoacridines; Antineoplastic Agents; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; Camptothecin; Carcinoma, Non-Small-Cell Lung; Cell Line, Tumor; Cell Survival; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Drug Screening Assays, Antitumor; Gene Amplification; Gene Expression Regulation, Neoplastic; Heterozygote; Humans; Indoles; Irinotecan; Mitoxantrone; Neoplasm Proteins; RNA, Messenger; Triazoles

2007
Time schedule-dependent effect of the CK2 inhibitor TBB on PC-3 human prostate cancer cell viability.
    Oncology reports, 2012, Volume: 27, Issue:1

    Topics: Antineoplastic Agents; Apoptosis; Camptothecin; Cell Line, Tumor; Cell Survival; Checkpoint Kinase 2; Enzyme Inhibitors; Humans; Male; Prostatic Neoplasms; Protein Serine-Threonine Kinases; TNF-Related Apoptosis-Inducing Ligand; Triazoles

2012
HSP90 Inhibitor-SN-38 Conjugate Strategy for Targeted Delivery of Topoisomerase I Inhibitor to Tumors.
    Molecular cancer therapeutics, 2015, Volume: 14, Issue:11

    Topics: Animals; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Blotting, Western; Camptothecin; Cell Line, Tumor; Female; HSP90 Heat-Shock Proteins; Humans; Irinotecan; Mice, Inbred ICR; Mice, SCID; Microscopy, Fluorescence; Molecular Targeted Therapy; Neoplasms; Resorcinols; Topoisomerase I Inhibitors; Treatment Outcome; Triazoles; Tumor Burden; Xenograft Model Antitumor Assays

2015
SMAC mimetic Debio 1143 synergizes with taxanes, topoisomerase inhibitors and bromodomain inhibitors to impede growth of lung adenocarcinoma cells.
    Oncotarget, 2015, Nov-10, Volume: 6, Issue:35

    Topics: Adenocarcinoma; Adenocarcinoma of Lung; Animals; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Apoptosis Regulatory Proteins; Azepines; Azocines; Benzhydryl Compounds; Camptothecin; Cell Line, Tumor; Cell Proliferation; Docetaxel; Dose-Response Relationship, Drug; Drug Synergism; Female; Humans; Irinotecan; Lung Neoplasms; Mice, Inbred BALB C; Mice, Nude; NF-kappa B; Paclitaxel; Signal Transduction; Taxoids; Time Factors; Topoisomerase Inhibitors; Triazoles; Tumor Burden; Xenograft Model Antitumor Assays

2015
Arsenic sulfide combined with JQ1, chemotherapy agents, or celecoxib inhibit gastric and colon cancer cell growth.
    Drug design, development and therapy, 2015, Volume: 9

    Topics: Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Arsenicals; Azepines; Camptothecin; Celecoxib; Cell Line, Tumor; Cisplatin; Colonic Neoplasms; Drug Synergism; Gene Expression Regulation, Neoplastic; Humans; Irinotecan; p38 Mitogen-Activated Protein Kinases; Stomach Neoplasms; Sulfides; Triazoles; Tumor Suppressor Protein p53

2015
Wnt/β-catenin pathway regulates MGMT gene expression in cancer and inhibition of Wnt signalling prevents chemoresistance.
    Nature communications, 2015, Nov-25, Volume: 6

    Topics: Animals; Antineoplastic Agents; Benzeneacetamides; beta Catenin; Brain Neoplasms; Camptothecin; Celecoxib; Cisplatin; Colorectal Neoplasms; Dacarbazine; DNA Modification Methylases; DNA Repair Enzymes; Doxorubicin; Drug Resistance, Neoplasm; Flow Cytometry; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Glioma; Glucose-6-Phosphate Isomerase; Heterocyclic Compounds, 3-Ring; Humans; Immunoblotting; Immunohistochemistry; Irinotecan; Medulloblastoma; Mice; Neoplasm Transplantation; Neoplasms; Neuroblastoma; Pyrans; Pyrazines; Pyridines; Real-Time Polymerase Chain Reaction; Sulfones; Temozolomide; Triazoles; Tumor Suppressor Proteins; Vincristine; Wnt Proteins; Wnt Signaling Pathway

2015
Discovery of 7-Methyl-10-Hydroxyhomocamptothecins with 1,2,3-Triazole Moiety as Potent Topoisomerase I Inhibitors.
    Chemical biology & drug design, 2016, Volume: 88, Issue:3

    Topics: Camptothecin; Cell Line; Cell Proliferation; Humans; Topoisomerase I Inhibitors; Triazoles

2016
Topoisomerase 1 inhibition suppresses inflammatory genes and protects from death by inflammation.
    Science (New York, N.Y.), 2016, May-27, Volume: 352, Issue:6289

    Topics: Animals; Azepines; Camptothecin; DNA Topoisomerases, Type I; Ebolavirus; Flavonoids; Gene Expression Regulation; HEK293 Cells; Hemorrhagic Fever, Ebola; Host-Pathogen Interactions; Humans; Immunity, Innate; Inflammation; Influenza A virus; Interferon-beta; Mice; Mice, Inbred C57BL; Piperidines; Positive Transcriptional Elongation Factor B; RNA Polymerase II; Sendai virus; Staphylococcal Infections; Staphylococcus aureus; Topoisomerase I Inhibitors; Topotecan; Transcription, Genetic; Triazoles

2016
Modulation of UDP-glucuronidation by acridinone antitumor agents C-1305 and C-1311 in HepG2 and HT29 cell lines, despite slight impact in noncellular systems.
    Pharmacological reports : PR, 2018, Volume: 70, Issue:3

    Topics: Acridines; Aminoacridines; Antineoplastic Agents; Camptothecin; Cell Line, Tumor; Glucuronides; Glucuronosyltransferase; Hep G2 Cells; HT29 Cells; Humans; Irinotecan; Isoenzymes; Microsomes, Liver; Triazoles

2018
Efficient Click Synthesis of a Protonized and Reduction-Sensitive Amphiphilic Small-Molecule Prodrug Containing Camptothecin and Gemcitabine for a Drug Self-Delivery System.
    Molecular pharmaceutics, 2019, 09-03, Volume: 16, Issue:9

    Topics: Animals; Antineoplastic Agents; Camptothecin; Cell Survival; Click Chemistry; Deoxycytidine; Drug Delivery Systems; Drug Liberation; Drug Stability; Gemcitabine; Half-Life; Hep G2 Cells; Humans; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Male; Nanoparticles; Prodrugs; Rats; Rats, Sprague-Dawley; Tissue Distribution; Triazoles

2019
The bromodomain and extra-terminal domain inhibitor JQ1 synergistically sensitizes human colorectal cancer cells to topoisomerase I inhibitors through repression of Mre11-mediated DNA repair pathway.
    Investigational new drugs, 2021, Volume: 39, Issue:2

    Topics: Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Azepines; Camptothecin; Cell Line, Tumor; Cell Survival; Colorectal Neoplasms; DNA Repair; Humans; MRE11 Homologue Protein; Topoisomerase I Inhibitors; Triazoles

2021
Integrated pan-cancer of AURKA expression and drug sensitivity analysis reveals increased expression of AURKA is responsible for drug resistance.
    Cancer medicine, 2021, Volume: 10, Issue:18

    Topics: Antineoplastic Combined Chemotherapy Protocols; Aurora Kinase A; Azepines; Benzodioxoles; Biomarkers, Tumor; Camptothecin; Cell Line, Tumor; Chromones; Dactinomycin; Datasets as Topic; Drug Resistance, Neoplasm; Female; Gene Expression Regulation, Neoplastic; Humans; Imidazoles; Irinotecan; Kaplan-Meier Estimate; Male; Middle Aged; Morpholines; Neoplasms; Prognosis; Pyridines; Triazoles

2021