triazoles has been researched along with caffeine in 98 studies
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 2 (2.04) | 18.7374 |
1990's | 12 (12.24) | 18.2507 |
2000's | 55 (56.12) | 29.6817 |
2010's | 27 (27.55) | 24.3611 |
2020's | 2 (2.04) | 2.80 |
Authors | Studies |
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Anderson, WH; Fitzpatrick, DF; Hwang, DP; Krzanowski, JJ; Polson, JB; Szentivanyi, A | 1 |
Adén, U; Fredholm, BB; Johansson, B; Lindström, K; Svenningsson, P | 1 |
Holtzman, SG | 1 |
Browne, RG; Howard, HR; Koe, BK; Lebel, LA; Sarges, R; Seymour, PA | 1 |
Collier, HO; Cuthbert, NJ; Francis, DL | 1 |
Dohi, T; Miyasako, T; Morita, K; Suemitsu, T; Uchiyama, Y | 1 |
Howell, LL | 1 |
Byrd, LD; Howell, LL | 1 |
Fenu, S; Morelli, M | 1 |
O'Regan, MH; Phillis, JW; Song, D | 1 |
Fredholm, BB; Johansson, B; Kuzmin, A; Zvartau, EE | 1 |
Fredholm, BB; Lindström, K | 1 |
Kopf, SR; Melani, A; Pedata, F; Pepeu, G | 1 |
Borgeat, P; Bourgoin, SG; Harbour, D; Naccache, PH; Thibault, N | 1 |
Costentin, J; El Yacoubi, M; Ledent, C; Parmentier, M; Vaugeois, JM | 2 |
Gean, PW; Lu, KT; Wu, SP | 1 |
Pèzzola, A; Popoli, P; Reggio, R | 1 |
Costentin, J; El Yacoubi, M; Ledent, C; Ménard, JF; Parmentier, M; Vaugeois, JM | 1 |
Belardinelli, L; Borea, PA; Gessi, S; Merighi, S; Ongini, E; Portaluppi, F; Varani, K | 1 |
Cauli, O; Fenu, S; Morelli, M | 1 |
Fredholm, BB; Halldner, L; Lindström, K; Lozza, G | 1 |
Beilstein, M; Castagnoli, K; Castagnoli, N; Chen, JF; Petzer, JP; Schwarzschild, MA; Sonsalla, PK; Staal, R; Xu, K; Xu, YH | 1 |
Hamann, M; Richter, A | 1 |
Costentin, J; El Yacoubi, M; Ledent, C; Ongini, E; Parmentier, M; Vaugeois, JM | 1 |
Acquas, E; Di Chiara, G; Tanda, G | 1 |
Anderson, KE; Daniele, N; Foukas, LC; Jensen, J; Ktori, C; Shepherd, PR | 1 |
Ferré, S; Goldberg, SR; Karcz-Kubicha, M; Popoli, P; Solinas, M; You, ZB | 1 |
Bibb, JA; Fienberg, AA; Fisone, G; Fredholm, BB; Greengard, P; Kim, Y; Lindskog, M; Nairn, AC; Pozzi, L; Svenningsson, P | 1 |
Allen, C; Christie, S; Göbel, H; Mateos, V; Shivaprakash, M; Vrijens, F | 1 |
Antoniou, K; Ferré, S; Fuxe, K; Goldberg, SR; Justinova, Z; Karcz-Kubicha, M; Müller, CE; Pezzola, A; Popoli, P; Quarta, D; Reggio, R; Solinas, M; Terasmaa, A | 1 |
Cunha, RA; Dall'Igna, OP; Dall'lgna, OP; Lara, DR; Porciúncula, LO; Souza, DO | 1 |
Berrino, L; Capuano, A; De Novellis, V; Filippelli, A; Mazzeo, F; Rossi, F; Stella, L; Vitelli, MR | 1 |
O'Regan, MH; Phillis, JW | 1 |
Brodmann, M; Lischnig, U; Lueger, A; Pilger, E; Stark, G | 1 |
Fredholm, BB; Svenningsson, P | 1 |
Gianfriddo, M; Melani, A; Pedata, F; Pugliese, AM | 1 |
Costentin, J; El Yacoubi, M; Vaugeois, JM | 1 |
Goulart, EC; Kaster, MP; Rodrigues, AL; Rosa, AO; Rosso, MM; Santos, AR | 1 |
Bremer, HC; Elsner, P; Girolomoni, G; Herouy, Y; Idzko, M; Mockenhaupt, M; Norgauer, J; Panther, E; Sorichter, S; Windisch, W | 1 |
Batista, LC; Prediger, RD; Takahashi, RN | 1 |
Connole, L; Harkin, A; Maginn, M | 1 |
Bennett, MR; Lin, YQ | 1 |
Prediger, RD; Takahashi, RN | 1 |
Fernandes, D; Prediger, RD; Takahashi, RN | 1 |
Hay, JW; Zhang, L | 1 |
Fredholm, BB; Gimenez, L; Johansson, B; Kuzmin, A; Ogren, SO | 1 |
Holý, A; Kmonícková, E; Potmesil, P; Zídek, Z | 1 |
Clarke, GD; Godfrey, L; Hourani, SM; Kitchen, I; Ledent, C; Yan, L | 1 |
Holý, A; Kmonícková, E; Krecmerová, M; Potmesil, P; Zídek, Z | 1 |
Chan, ES; Chen, JF; Cronstein, BN; Delano, DL; Desai, A; Fernandez, P; Friedman, SL; Montesinos, MC; Pillinger, MH; Reiss, AB; Schwarzschild, MA; Yee, H | 1 |
Conde, SV; Gonzalez, C; Obeso, A; Rigual, R; Rocher, A; Vicario, I | 1 |
Cunha, RA; Dall'Igna, OP; Fett, P; Gomes, MW; Lara, DR; Souza, DO | 1 |
Bairam, A; Kinkead, R; Montandon, G | 2 |
Desfrere, L; Gressens, P; Olivier, P; Schwendimann, L; Verney, C | 1 |
Binfaré, RW; Budni, J; Lobato, KR; Rodrigues, AL; Rosa, AO; Santos, AR | 1 |
Coskun, C; Mutlu, D; Savci, V; Suzer, O; Yalcin, M; Yilmaz, MS | 1 |
Jesse, CR; Nogueira, CW; Savegnago, L | 1 |
Grzelak, ME; Hodgson, RA; Hunter, JC; Parker, EM; Pond, AJ; Varty, GB | 1 |
Cormack, LK; Feinberg, LM; Schallert, K; Schallert, T; Spinetta, MJ; Stroud, C; Woodlee, MT | 1 |
Ahlawat, R; Chavez-Valdez, R; Cristofalo, EA; Gauda, EB; Nathan, A; Wills-Karp, M | 1 |
Baghdoyan, HA; Lydic, R; Van Dort, CJ | 1 |
Chen, CY; Chiu, TH; Hsu, CW; Wang, CS | 1 |
Fernandes, D; Pamplona, FA; Pandolfo, P; Pires, VA; Prediger, RD; Takahashi, RN | 1 |
Goode, T; Harris, A; Trevitt, J; Vallance, C | 1 |
Arbogast, LA; Hughes, LF; Mhaskar, Y; Toth, LA; Trammell, RA; Xie, X | 1 |
Jalali, A; Kawa, K; Larsen, C; Trevitt, J | 1 |
Agostinho, PM; Cognato, GP; Cunha, RA; Hockemeyer, J; Müller, CE; Souza, DO | 1 |
Canas, PM; Cunha, GM; Cunha, RA; Machado, NJ; Oliveira, CR; Oliveira, JM; Porciúncula, LO; Silva, CG | 1 |
Eyanagi, R; Imoto, M; Kuroki, H; Nishimura, S; Shimeno, H; Soeda, S; Toda, A; Uchiyama, H; Watanabe, S | 1 |
Boeck, CR; Calo', G; de Castro, AA; Dos Santos Casagrande, T; Gavioli, EC; Guerrini, R; Martinello, C; Moretti, M | 1 |
Chiu, TH; Hsu, CW; Wang, CS | 1 |
Brandão, R; Jesse, CR; Leite, MR; Nogueira, CW; Wilhelm, EA | 1 |
Dziubina, A; Gołembiowska, K | 2 |
Bennett, K; Congreve, M; Doré, AS; Errey, JC; Hollenstein, K; Hurrell, E; Magnani, F; Marshall, FH; Ng, I; Robertson, N; Tate, CG; Tehan, B; Weir, M | 1 |
Ayers, PW; Burger, SK; Liu, Y; Vöhringer-Martinez, E | 1 |
Azevedo, MS; Cechinel-Filho, V; Ferreira, VM; Lucena, GM; Matheus, FC; Prediger, RD; Tessele, PB | 1 |
Martins, DF; Mazzardo-Martins, L; Piovezan, AP; Santos, AR; Soldi, F; Stramosk, J | 1 |
Manian, S; Marimuthu, S; Sowndhararajan, K | 1 |
Canuti, E; Loos, R; Paracchini, B; Tavazzi, S; Weissteiner, C | 1 |
Edling, CE; Falasca, M; Ghonaim, R; Maffucci, T; Selvaggi, F | 1 |
Dubroqua, S; Singer, P; Yee, BK | 1 |
Gao, N; Guan, X; Li, J; Shen, J; Sun, B; Xiong, X; Zhang, J | 1 |
Andriolo, V; Castorina, A; Giunta, S | 1 |
Baxter, C; Edgar, DM; Gilmour, G; Kellett, DO; Loomis, S; McCarthy, A; Tricklebank, M | 1 |
Hiromura, M; Honda, S; Inoue, K; Kosako, K; Kuroki, H; Shiratani, T; Soeda, S; Toda, A; Uchiyama, H | 1 |
Chaimovitz, C; Douvdevani, A; Eini, H; Frishman, V; Kachko, L; Lewis, EC; Yulzari, R | 1 |
Akhtar, S; Desai, A; Goldwater, R; Han, D; Howieson, C; Kowalski, D; Lademacher, C; Pearlman, H; Rammelsberg, D; Townsend, R; Yamazaki, T | 1 |
Ishikawa, T; Nakamura, M; Nishiyama, R; Saito, SY; Todoroki, K; Toyo'oka, T; Yamaguchi, M | 1 |
Chowdhury, AN; Fong, R; Fox, AP; Khokhar, S; Wong, JH; Xie, KG; Xie, Z | 1 |
Bai, X; He, J; Li, T; Qiao, H; Xu, J; Ye, X; Zhang, J; Zhang, W | 1 |
Colmenero, AV; Gabel, M; Hambrecht-Wiedbusch, VS; Imperial, JP; Liu, LJ; Vanini, G | 1 |
Bajnok, A; Orbán, C; Sava, F; Toldi, G; Vásárhelyi, Z | 1 |
Gom, RC; Phillips, TJ; Teskey, GC; Wolff, MD | 1 |
Collares, FM; Cunha, RA; de Souza Balbinot, G; Lima, RR; Maia, C; Martins Ferreira, MK; Martins, MD; Pinheiro, BG; Schmidt, TR; Soares da Silva, CC; Souza-Monteiro, D | 1 |
Bharate, SB; Bhatt, S; Nandi, U; Nuthakki, VK; Sharma, A; Sharma, M | 1 |
2 review(s) available for triazoles and caffeine
Article | Year |
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Adenosine-dopamine interactions: development of a concept and some comments on therapeutic possibilities.
Topics: Adenosine; Adenosine A2 Receptor Antagonists; Animals; Caffeine; Corpus Striatum; Dopamine; Dopamine and cAMP-Regulated Phosphoprotein 32; Humans; Mice; Nerve Tissue Proteins; Parkinson Disease; Phosphoproteins; Phosphorylation; Pyrimidines; Receptor, Adenosine A2A; Receptors, Dopamine D2; Signal Transduction; Triazoles | 2003 |
Cost-effectiveness analysis of rizatriptan and sumatriptan versus Cafergot in the acute treatment of migraine.
Topics: Caffeine; Cost-Benefit Analysis; Drug Combinations; Drug Therapy, Combination; Economics, Pharmaceutical; Ergotamine; Humans; Migraine Disorders; Serotonin Receptor Agonists; Sumatriptan; Triazoles; Tryptamines | 2005 |
2 trial(s) available for triazoles and caffeine
Article | Year |
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Crossover comparison of efficacy and preference for rizatriptan 10 mg versus ergotamine/caffeine in migraine.
Topics: Adolescent; Adult; Aged; Caffeine; Cross-Over Studies; Double-Blind Method; Drug Combinations; Ergotamine; Female; Humans; Male; Middle Aged; Migraine Disorders; Pain Measurement; Patient Satisfaction; Serotonin Receptor Agonists; Triazoles; Tryptamines | 2003 |
Pharmacokinetic Effects of Isavuconazole Coadministration With the Cytochrome P450 Enzyme Substrates Bupropion, Repaglinide, Caffeine, Dextromethorphan, and Methadone in Healthy Subjects.
Topics: Adult; Area Under Curve; Bupropion; Caffeine; Carbamates; Cytochrome P-450 Enzyme System; Dextromethorphan; Drug Interactions; Female; Healthy Volunteers; Humans; Male; Methadone; Middle Aged; Nitriles; Piperidines; Pyridines; Triazoles; Young Adult | 2017 |
94 other study(ies) available for triazoles and caffeine
Article | Year |
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Analysis of the relationship between pharmacological inhibition of cyclic nucleotide phosphodiesterase and relaxation of canine tracheal smooth muscle.
Topics: 1-Methyl-3-isobutylxanthine; 3',5'-Cyclic-AMP Phosphodiesterases; 3',5'-Cyclic-GMP Phosphodiesterases; Airway Resistance; Animals; Caffeine; Dogs; Etazolate; Female; In Vitro Techniques; Muscle Contraction; Muscle Relaxation; Muscle, Smooth; Phosphodiesterase Inhibitors; Pyrazines; Theophylline; Trachea; Triazoles | 1979 |
Evidence that the increase in striatal c-fos following acute high-dose caffeine is not due to direct interaction with striatal adenosine receptors.
Topics: Adenosine; Animals; Caffeine; Corpus Striatum; Dose-Response Relationship, Drug; Genes, fos; Purinergic Antagonists; Quinazolines; Rats; RNA, Messenger; Triazoles; Xanthines | 1992 |
CGS 15943, a nonxanthine adenosine receptor antagonist: effects on locomotor activity of nontolerant and caffeine-tolerant rats.
Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Caffeine; Dose-Response Relationship, Drug; Drug Tolerance; Male; Motor Activity; Quinazolines; Rats; Rats, Inbred Strains; Triazoles | 1991 |
4-Amino[1,2,4]triazolo[4,3-a]quinoxalines. A novel class of potent adenosine receptor antagonists and potential rapid-onset antidepressants.
Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Antidepressive Agents; Behavior, Animal; Caffeine; Cats; Cell Membrane; Cerebral Cortex; Chemical Phenomena; Chemistry; Corpus Striatum; Male; Molecular Structure; Motor Activity; Purinergic Antagonists; Quinoxalines; Rats; Receptors, Purinergic; Sleep; Structure-Activity Relationship; Triazoles | 1990 |
Character and meaning of quasi-morphine withdrawal phenomena elicited by methylxanthines.
Topics: 1-Methyl-3-isobutylxanthine; 4-(3-Butoxy-4-methoxybenzyl)-2-imidazolidinone; Animals; Caffeine; Humans; Hypoxanthines; Morphine Dependence; Naloxone; Narcotic Antagonists; Narcotics; Opioid-Related Disorders; Phosphodiesterase Inhibitors; Pyrimidines; Rats; Substance Withdrawal Syndrome; Theobromine; Theophylline; Triazoles; Xanthines | 1981 |
Platelet-activating factor mediated potentiation of stimulation-evoked catecholamine release and the rise in intracellular free Ca2+ concentration in adrenal chromaffin cells.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Acetylcholine; Adrenal Glands; Animals; Azepines; Caffeine; Calcium; Catecholamines; Cattle; Cells, Cultured; Chromaffin Granules; Dose-Response Relationship, Drug; Kinetics; Platelet Activating Factor; Platelet Membrane Glycoproteins; Potassium Chloride; Receptors, Cell Surface; Receptors, G-Protein-Coupled; Stimulation, Chemical; Time Factors; Triazoles | 1995 |
Comparative effects of caffeine and selective phosphodiesterase inhibitors on respiration and behavior in rhesus monkeys.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Behavior, Animal; Caffeine; Carbon Dioxide; Conditioning, Psychological; Female; Macaca mulatta; Male; Phosphodiesterase Inhibitors; Quinazolines; Respiration; Triazoles | 1993 |
Effects of CGS 15943, a nonxanthine adenosine antagonist, on behavior in the squirrel monkey.
Topics: Animals; Behavior, Animal; Caffeine; Drug Interactions; Drug Synergism; Male; Purinergic P1 Receptor Antagonists; Pyrrolidinones; Quinazolines; Receptors, Purinergic P1; Rolipram; Saimiri; Time Factors; Triazoles | 1993 |
Motor stimulant effects of caffeine in 6-hydroxydopamine-lesioned rats are dependent on previous stimulation of dopamine receptors: a different role of D1 and D2 receptors.
Topics: Animals; Apomorphine; Caffeine; Central Nervous System Stimulants; Dopamine Agonists; Male; Motor Activity; Oxidopamine; Purinergic P1 Receptor Antagonists; Pyrimidines; Rats; Rats, Sprague-Dawley; Receptors, Dopamine D1; Receptors, Dopamine D2; Rotation; Stimulation, Chemical; Triazoles; Xanthines | 1998 |
The role of adenosine in rat coronary flow regulation during respiratory and metabolic acidosis.
Topics: Acidosis; Acidosis, Respiratory; Adenosine; Animals; Caffeine; Coronary Circulation; Hypercapnia; Male; Purinergic P1 Receptor Antagonists; Pyrimidines; Rats; Rats, Sprague-Dawley; Theophylline; Triazines; Triazoles | 1998 |
Caffeine, acting on adenosine A(1) receptors, prevents the extinction of cocaine-seeking behavior in mice.
Topics: Animals; Behavior, Animal; Caffeine; Cocaine; Extinction, Psychological; Male; Mice; Mice, Inbred DBA; Purinergic P1 Receptor Antagonists; Pyrimidines; Quinazolines; Reward; Substance Abuse, Intravenous; Theophylline; Triazoles; Xanthines | 1999 |
Autoradiographic comparison of the potency of several structurally unrelated adenosine receptor antagonists at adenosine A1 and A(2A) receptors.
Topics: Adenosine; Animals; Autoradiography; Binding, Competitive; Brain; Caffeine; In Vitro Techniques; Male; Phenethylamines; Purinergic P1 Receptor Antagonists; Pyrazines; Quinazolines; Rats; Rats, Sprague-Dawley; Receptor, Adenosine A2A; Receptors, Purinergic P1; Theophylline; Triazines; Triazoles; Tritium; Xanthines | 1999 |
Adenosine and memory storage: effect of A(1) and A(2) receptor antagonists.
Topics: Adenosine; Animals; Avoidance Learning; Caffeine; Central Nervous System Stimulants; Male; Memory; Mice; Purinergic P1 Receptor Antagonists; Pyrimidines; Triazoles; Xanthines | 1999 |
Adenosine receptor occupancy suppresses chemoattractant-induced phospholipase D activity by diminishing membrane recruitment of small GTPases.
Topics: Adenosine; Adenosine Deaminase; Adenosine-5'-(N-ethylcarboxamide); ADP-Ribosylation Factor 1; Adult; Caffeine; Cell Membrane; Enzyme Activation; GTP Phosphohydrolases; Humans; In Vitro Techniques; Isoenzymes; Kinetics; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Phenethylamines; Phospholipase D; Protein Kinase C; Protein Kinase C-alpha; Purinergic P1 Receptor Antagonists; Quinazolines; Receptor, Adenosine A2A; Receptors, Purinergic P1; rhoA GTP-Binding Protein; Triazoles | 2000 |
The anxiogenic-like effect of caffeine in two experimental procedures measuring anxiety in the mouse is not shared by selective A(2A) adenosine receptor antagonists.
Topics: Adenosine; Administration, Oral; Animals; Anxiety; Behavior, Animal; Caffeine; Darkness; Drug Administration Schedule; Injections, Intraperitoneal; Light; Male; Maze Learning; Mice; Mice, Knockout; Neuroprotective Agents; Phenethylamines; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Pyrimidines; Reaction Time; Receptor, Adenosine A2A; Triazines; Triazoles; Xanthines | 2000 |
Promotion of forskolin-induced long-term potentiation of synaptic transmission by caffeine in area CA1 of the rat hippocampus.
Topics: Adenosine; Animals; Anti-Inflammatory Agents, Non-Steroidal; Caffeine; Central Nervous System Stimulants; Colforsin; Cyclic AMP; Drug Synergism; Excitatory Postsynaptic Potentials; Hippocampus; Long-Term Potentiation; Male; Quinazolines; Rats; Rats, Sprague-Dawley; Synaptic Transmission; Triazoles; Xanthines | 1999 |
Effects of SCH 58261, an adenosine A(2A) receptor antagonist, on quinpirole-induced turning in 6-hydroxydopamine-lesioned rats. Lack of tolerance after chronic caffeine intake.
Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Animals; Behavior, Animal; Caffeine; Central Nervous System Stimulants; Dopamine Agonists; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Tolerance; Male; Motor Activity; Neuroprotective Agents; Parkinson Disease; Purinergic P1 Receptor Antagonists; Pyrimidines; Quinpirole; Rats; Rats, Sprague-Dawley; Receptor, Adenosine A2A; Time Factors; Triazoles | 2000 |
The stimulant effects of caffeine on locomotor behaviour in mice are mediated through its blockade of adenosine A(2A) receptors.
Topics: Analysis of Variance; Animals; Behavior, Animal; Caffeine; Central Nervous System Stimulants; Dose-Response Relationship, Drug; Habituation, Psychophysiologic; Male; Mice; Mice, Knockout; Motor Activity; Purinergic P1 Receptor Antagonists; Pyrimidines; Receptor, Adenosine A2A; Receptors, Purinergic P1; Triazoles; Xanthines | 2000 |
Dose and time effects of caffeine intake on human platelet adenosine A(2A) receptors : functional and biochemical aspects.
Topics: Adenosine-5'-(N-ethylcarboxamide); Adult; Blood Platelets; Caffeine; Calcium; Cyclic AMP; Dose-Response Relationship, Drug; Female; Humans; Male; Middle Aged; Myocardium; Platelet Aggregation; Platelet Aggregation Inhibitors; Purinergic P1 Receptor Agonists; Pyrimidines; Receptor, Adenosine A2A; Receptors, Purinergic P1; Time Factors; Triazoles; Up-Regulation | 2000 |
Cross-sensitization between the motor activating effects of bromocriptine and caffeine: role of adenosine A(2A) receptors.
Topics: Animals; Bromocriptine; Caffeine; Central Nervous System Stimulants; Dopamine Agonists; Dose-Response Relationship, Drug; Male; Motor Activity; Purinergic P1 Receptor Antagonists; Pyrimidines; Rats; Rats, Sprague-Dawley; Receptor, Adenosine A2A; Receptors, Purinergic P1; Stereotyped Behavior; Stimulation, Chemical; Triazoles | 2000 |
Lack of tolerance to motor stimulant effects of a selective adenosine A(2A) receptor antagonist.
Topics: Animals; Apomorphine; Caffeine; Drug Tolerance; Genes, Immediate-Early; Male; Motor Activity; Purinergic P1 Receptor Antagonists; Pyrimidines; Rats; Rats, Sprague-Dawley; Receptors, Dopamine; Receptors, Purinergic P1; RNA, Messenger; Triazoles | 2000 |
Neuroprotection by caffeine and A(2A) adenosine receptor inactivation in a model of Parkinson's disease.
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; 3,4-Dihydroxyphenylacetic Acid; Animals; Caffeine; Catechols; Corpus Striatum; Disease Models, Animal; Dopamine; Dose-Response Relationship, Drug; Immunity, Innate; Injections, Intraperitoneal; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Neuroprotective Agents; Parkinsonian Disorders; Purinergic P1 Receptor Antagonists; Purines; Pyrimidines; Receptor, Adenosine A2A; Receptors, Purinergic P1; Theobromine; Triazoles; Xanthines | 2001 |
Effects of adenosine receptor agonists and antagonists in a genetic animal model of primary paroxysmal dystonia.
Topics: Adenosine; Animals; Caffeine; Cricetinae; Disease Models, Animal; Dose-Response Relationship, Drug; Dystonia; Female; Male; Mesocricetus; Muscle Contraction; Mutation; Phenethylamines; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Quinazolines; Theobromine; Theophylline; Triazines; Triazoles; Xanthines | 2001 |
In vivo labelling of the adenosine A2A receptor in mouse brain using the selective antagonist [3H]SCH 58261.
Topics: Adenosine; Animals; Binding Sites; Binding, Competitive; Blood-Brain Barrier; Brain; Caffeine; Dose-Response Relationship, Drug; Drug Interactions; Male; Mice; Mice, Knockout; Neurons; Neuroprotective Agents; Phosphodiesterase Inhibitors; Purinergic P1 Receptor Antagonists; Pyrimidines; Radioligand Assay; Receptor, Adenosine A2A; Receptors, Purinergic P1; Triazoles; Tritium | 2001 |
Differential effects of caffeine on dopamine and acetylcholine transmission in brain areas of drug-naive and caffeine-pretreated rats.
Topics: Acetylcholine; Animals; Behavior, Animal; Caffeine; Central Nervous System Stimulants; Dopamine; Dose-Response Relationship, Drug; Drug Administration Schedule; Extracellular Space; Injections, Intraperitoneal; Male; Microdialysis; Neuroprotective Agents; Nucleus Accumbens; Prefrontal Cortex; Presynaptic Terminals; Pyrimidines; Rats; Rats, Sprague-Dawley; Synaptic Transmission; Triazoles; Xanthines | 2002 |
Direct effects of caffeine and theophylline on p110 delta and other phosphoinositide 3-kinases. Differential effects on lipid kinase and protein kinase activities.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Biological Transport; Caffeine; CHO Cells; Cricetinae; Deoxyglucose; Dimerization; Flavins; Glucose; Kinetics; Monosaccharide Transport Proteins; Phosphatidylinositol 3-Kinases; Phosphorylation; Quinazolines; Recombinant Fusion Proteins; Theophylline; Transfection; Triazoles | 2002 |
Caffeine induces dopamine and glutamate release in the shell of the nucleus accumbens.
Topics: Animals; Behavior, Animal; Caffeine; Dopamine; Dose-Response Relationship, Drug; Extracellular Space; Glutamic Acid; Injections, Intraperitoneal; Male; Microdialysis; Motor Activity; Nucleus Accumbens; Purinergic P1 Receptor Antagonists; Pyrimidines; Rats; Rats, Sprague-Dawley; Receptor, Adenosine A2A; Theophylline; Triazoles; Wakefulness | 2002 |
Involvement of DARPP-32 phosphorylation in the stimulant action of caffeine.
Topics: Adenosine; Animals; Caffeine; Central Nervous System Stimulants; Cyclin-Dependent Kinase 5; Cyclin-Dependent Kinases; Dopamine and cAMP-Regulated Phosphoprotein 32; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Motor Activity; Neostriatum; Nerve Tissue Proteins; Neurons; Phenethylamines; Phosphoproteins; Phosphorylation; Phosphothreonine; Purinergic P1 Receptor Antagonists; Pyrimidines; Receptors, Purinergic P1; Triazoles | 2002 |
Involvement of adenosine A1 and A2A receptors in the motor effects of caffeine after its acute and chronic administration.
Topics: Adenosine; Amphetamine; Animals; Behavior, Animal; Caffeine; Central Nervous System Stimulants; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Interactions; Male; Motor Activity; Phenethylamines; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Radioligand Assay; Rats; Rats, Sprague-Dawley; Receptor, Adenosine A2A; Receptors, Purinergic P1; Theophylline; Time Factors; Triazines; Triazoles; Tritium; Xanthines | 2003 |
Neuroprotection by caffeine and adenosine A2A receptor blockade of beta-amyloid neurotoxicity.
Topics: Adenosine A2 Receptor Antagonists; Alzheimer Disease; Amyloid beta-Peptides; Animals; Brain; Caffeine; Cells, Cultured; Central Nervous System Diseases; Cerebellum; Neurons; Neuroprotective Agents; Peptide Fragments; Rats; Rats, Wistar; Receptor, Adenosine A2A; Theophylline; Triazines; Triazoles | 2003 |
Interactive role of adenosine and dopamine in the opiate withdrawal syndrome.
Topics: Adenosine; Adenosine A1 Receptor Agonists; Adenosine A2 Receptor Antagonists; Animals; Caffeine; Chromatography, High Pressure Liquid; Dopamine; Injections, Subcutaneous; Male; Microdialysis; Morphine; Pyrimidines; Rats; Rats, Wistar; Receptors, Dopamine; Substance Withdrawal Syndrome; Triazoles | 2003 |
Effects of adenosine receptor antagonists on pial arteriolar dilation during carbon dioxide inhalation.
Topics: Adenosine; Administration, Inhalation; Animals; Caffeine; Carbon Dioxide; Cerebral Cortex; Cerebral Veins; Cerebrovascular Circulation; Drug Interactions; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Purinergic P1 Receptor Antagonists; Quinazolines; Rats; Rats, Sprague-Dawley; Triazines; Triazoles; Vasodilation; Vasodilator Agents; Xanthines | 2003 |
The effect of caffeine on peripheral vascular resistance in isolated perfused guinea pig hind limbs.
Topics: Adenosine; Animals; Caffeine; Dose-Response Relationship, Drug; Female; Flavins; Guinea Pigs; Hindlimb; Hypoxia; Iliac Artery; Iloprost; Male; Nitrogen; Norepinephrine; Perfusion; Triazines; Triazoles; Vascular Resistance; Vasoconstriction; Vasodilation | 2003 |
Caffeine reduces hypnotic effects of alcohol through adenosine A2A receptor blockade.
Topics: Adenosine A1 Receptor Antagonists; Adenosine A2 Receptor Antagonists; Animals; Body Temperature; Caffeine; Central Nervous System Depressants; Central Nervous System Stimulants; Dipyridamole; Drug Overdose; Ethanol; Hypnotics and Sedatives; Male; Mice; Mice, Knockout; Neuroprotective Agents; Pentobarbital; Postural Balance; Pyrimidines; Receptor, Adenosine A2A; Triazoles; Vasodilator Agents; Xanthines | 2003 |
A2A receptors in neuroprotection of dopaminergic neurons.
Topics: Adenosine A2 Receptor Antagonists; Animals; Caffeine; Disease Models, Animal; Dopamine; Dose-Response Relationship, Drug; Enzyme Inhibitors; Female; Humans; Male; Neurons; Neuroprotective Agents; Parkinson Disease; Purines; Pyrimidines; Receptor, Adenosine A2A; Sex Factors; Triazoles | 2003 |
Adenosine A2A receptors and depression.
Topics: Adenosine; Adenosine A2 Receptor Antagonists; Animals; Antidepressive Agents; Behavior, Animal; Caffeine; Depression; Disease Models, Animal; Dopamine Antagonists; Drug Interactions; Haloperidol; Mice; Mice, Knockout; Motor Activity; Neurotransmitter Agents; Parkinsonian Disorders; Purines; Pyrimidines; Receptor, Adenosine A2A; Triazines; Triazoles | 2003 |
Adenosine administration produces an antidepressant-like effect in mice: evidence for the involvement of A1 and A2A receptors.
Topics: Adenosine; Animals; Antidepressive Agents; Caffeine; Depressive Disorder; Disease Models, Animal; Female; Male; Mice; Motor Activity; Receptor, Adenosine A1; Receptor, Adenosine A2A; Stress, Psychological; Triazines; Triazoles; Xanthines | 2004 |
Inosine stimulates chemotaxis, Ca2+-transients and actin polymerization in immature human dendritic cells via a pertussis toxin-sensitive mechanism independent of adenosine receptors.
Topics: Actins; Antigens, CD; Caffeine; Calcium; Cell Differentiation; Chemotaxis; Cytokines; Dendritic Cells; Dose-Response Relationship, Drug; Flow Cytometry; Histocompatibility Antigens Class I; Humans; Inosine; Pertussis Toxin; Purinergic P1 Receptor Antagonists; Quinazolines; Receptors, Purinergic P1; Triazoles; Xanthines | 2004 |
Adenosine A1 receptors modulate the anxiolytic-like effect of ethanol in the elevated plus-maze in mice.
Topics: Adenosine; Adenosine A1 Receptor Agonists; Adenosine A1 Receptor Antagonists; Adenosine A2 Receptor Antagonists; Analysis of Variance; Animals; Anti-Anxiety Agents; Anxiety; Caffeine; Dose-Response Relationship, Drug; Drug Synergism; Ethanol; Male; Maze Learning; Mice; Receptor, Adenosine A1; Triazines; Triazoles; Xanthines | 2004 |
Adenosine A1 receptor blockade mimics caffeine's attenuation of ethanol-induced motor incoordination.
Topics: Adenosine A1 Receptor Antagonists; Animals; Caffeine; Central Nervous System Depressants; Drug Interactions; Ethanol; Male; Motor Skills; Purinergic P1 Receptor Antagonists; Pyrimidines; Rats; Rats, Sprague-Dawley; Triazoles; Xanthines | 2004 |
Varicosity-Schwann cell interactions mediated by ATP in the mouse vas deferens.
Topics: Adenosine Triphosphate; Adrenergic Fibers; Aniline Compounds; Animals; Caffeine; Calcium; Cell Count; Drug Interactions; Electric Stimulation; Estrenes; Evoked Potentials; Fluorescent Dyes; Immunohistochemistry; In Vitro Techniques; Male; Mice; Mice, Inbred BALB C; Organic Chemicals; Phosphodiesterase Inhibitors; Platelet Aggregation Inhibitors; Pyridoxal Phosphate; Pyrrolidinones; Quinazolines; S100 Proteins; Schwann Cells; Suramin; Time Factors; Triazoles; Uridine Triphosphate; Vas Deferens; Xanthenes | 2005 |
Modulation of short-term social memory in rats by adenosine A1 and A(2A) receptors.
Topics: Adenosine; Animals; Behavior, Animal; Brain; Caffeine; Dose-Response Relationship, Drug; Drug Administration Schedule; Injections, Intraperitoneal; Male; Memory, Short-Term; Rats; Rats, Wistar; Receptor, Adenosine A1; Receptor, Adenosine A2A; Social Behavior; Triazines; Triazoles; Xanthines | 2005 |
Blockade of adenosine A2A receptors reverses short-term social memory impairments in spontaneously hypertensive rats.
Topics: Adenosine A2 Receptor Antagonists; Analysis of Variance; Animals; Caffeine; Discrimination Learning; Habituation, Psychophysiologic; Male; Memory Disorders; Memory, Short-Term; Rats; Rats, Inbred SHR; Rats, Wistar; Receptor, Adenosine A2A; Recognition, Psychology; Smell; Social Behavior; Social Environment; Species Specificity; Triazines; Triazoles; Xanthines | 2005 |
Combination of adenosine A1 and A2A receptor blocking agents induces caffeine-like locomotor stimulation in mice.
Topics: Adenosine A1 Receptor Antagonists; Adenosine A2 Receptor Antagonists; Animals; Brain Chemistry; Caffeine; Central Nervous System Stimulants; Dose-Response Relationship, Drug; Early Growth Response Protein 1; In Situ Hybridization; Male; Mice; Mice, Inbred C57BL; Motor Activity; Neuroprotective Agents; Pyrimidines; RNA, Messenger; Triazoles; Xanthines | 2006 |
Purine P1 receptor-dependent immunostimulatory effects of antiviral acyclic analogues of adenine and 2,6-diaminopurine.
Topics: 2-Aminopurine; Adenine; Adjuvants, Immunologic; Animals; Anti-HIV Agents; Caffeine; Cell Survival; Cells, Cultured; Chemokine CCL3; Chemokine CCL4; Chemokine CCL5; Dihydropyridines; Dose-Response Relationship, Drug; Female; Flavins; Humans; Interleukin-10; Lipopolysaccharides; Macrophage Inflammatory Proteins; Macrophages; Mice; Mice, Inbred C57BL; Molecular Structure; Organophosphonates; Purinergic P1 Receptor Antagonists; Quinazolines; Receptors, Purinergic P1; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Theophylline; Triazoles; Tumor Necrosis Factor-alpha | 2006 |
Modulation of paracetamol antinociception by caffeine and by selective adenosine A2 receptor antagonists in mice.
Topics: Acetaminophen; Adenosine A2 Receptor Antagonists; Analgesics, Non-Narcotic; Animals; Caffeine; Central Nervous System Stimulants; Dose-Response Relationship, Drug; Female; Male; Mice; Mice, Knockout; Neuroprotective Agents; Nociceptors; Pain; Pain Measurement; Pyrimidines; Receptor, Adenosine A2A; Receptor, Adenosine A2B; Sulfonic Acids; Time Factors; Triazoles; Xanthines | 2006 |
Nucleotide analogues with immunobiological properties: 9-[2-Hydroxy-3-(phosphonomethoxy)propyl]-adenine (HPMPA), -2,6-diaminopurine (HPMPDAP), and their N6-substituted derivatives.
Topics: Adenine; Animals; Caffeine; Cell Survival; Cytokines; Dihydropyridines; Dose-Response Relationship, Drug; Female; Gene Expression; Interferon-gamma; Lipopolysaccharides; Macrophages, Peritoneal; Mice; Mice, Inbred C57BL; Molecular Structure; Nitric Oxide; Nitric Oxide Synthase Type II; Nucleotides; Organophosphonates; Organophosphorus Compounds; Purinergic P1 Receptor Antagonists; Quinazolines; Receptors, Purinergic P1; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Triazoles | 2006 |
Adenosine A(2A) receptors play a role in the pathogenesis of hepatic cirrhosis.
Topics: Adenosine; Adenosine A2 Receptor Agonists; Animals; Blotting, Western; Caffeine; Carbon Tetrachloride; Cell Line; Chromatography, High Pressure Liquid; Ethanol; Hepatocytes; Humans; Liver Cirrhosis; Matrix Metalloproteinases, Membrane-Associated; Methotrexate; Mice; Mice, Inbred C57BL; Rats; Receptor, Adenosine A2A; Reverse Transcriptase Polymerase Chain Reaction; Thioacetamide; Triazines; Triazoles | 2006 |
Caffeine inhibition of rat carotid body chemoreceptors is mediated by A2A and A2B adenosine receptors.
Topics: Adenosine; Animals; Caffeine; Carotid Body; Catecholamines; Central Nervous System Stimulants; Chemoreceptor Cells; Dose-Response Relationship, Drug; Female; Hypoxia; Immunohistochemistry; Male; Potassium; Rats; Rats, Wistar; Receptor, Adenosine A2A; Receptor, Adenosine A2B; Receptors, Presynaptic; Respiratory Mechanics; Triazines; Triazoles; Xanthines | 2006 |
Caffeine and adenosine A(2a) receptor antagonists prevent beta-amyloid (25-35)-induced cognitive deficits in mice.
Topics: Adenosine A2 Receptor Antagonists; Alzheimer Disease; Amnesia; Amyloid beta-Peptides; Animals; Avoidance Learning; Brain; Caffeine; Cognition Disorders; Disease Models, Animal; Drug Synergism; Male; Maze Learning; Mice; Neuroprotective Agents; Peptide Fragments; Phosphodiesterase Inhibitors; Pyrimidines; Receptor, Adenosine A2A; Treatment Outcome; Triazoles | 2007 |
Disruption of adenosinergic modulation of ventilation at rest and during hypercapnia by neonatal caffeine in young rats: role of adenosine A(1) and A(2A) receptors.
Topics: Adenosine A1 Receptor Antagonists; Adenosine A2 Receptor Antagonists; Animals; Caffeine; Central Nervous System Stimulants; Hypercapnia; Injections, Intraperitoneal; Male; Plethysmography; Pulmonary Ventilation; Rats; Rats, Sprague-Dawley; Receptor, Adenosine A1; Receptor, Adenosine A2A; Rest; Time Factors; Triazines; Triazoles; Xanthines | 2007 |
Transient inhibition of astrocytogenesis in developing mouse brain following postnatal caffeine exposure.
Topics: Adenosine; Animals; Animals, Newborn; Apoptosis; Astrocytes; Behavior, Animal; Body Weight; Brain; Caffeine; Cell Differentiation; Cell Proliferation; Dose-Response Relationship, Drug; Glial Fibrillary Acidic Protein; Immunohistochemistry; Injections, Intraperitoneal; Mice; Microtubule-Associated Proteins; Models, Animal; Nerve Growth Factors; Organ Size; Phenethylamines; Pyrimidines; Receptor, Adenosine A2A; S100 Calcium Binding Protein beta Subunit; S100 Proteins; Synaptophysin; Time Factors; Triazoles | 2007 |
Involvement of the adenosine A1 and A2A receptors in the antidepressant-like effect of zinc in the forced swimming test.
Topics: Adenosine; Adenosine A1 Receptor Agonists; Adenosine A2 Receptor Agonists; Aniline Compounds; Animals; Antidepressive Agents; Caffeine; Central Nervous System Stimulants; Dipyridamole; Female; Male; Mice; Motor Activity; Nucleoside Transport Proteins; Receptor, Adenosine A1; Receptor, Adenosine A2A; Swimming; Triazines; Triazoles; Xanthines; Zinc | 2008 |
Hypotensive effects of intravenously administered uridine and cytidine in conscious rats: involvement of adenosine receptors.
Topics: Adenosine; Adenosine A1 Receptor Agonists; Adenosine A2 Receptor Agonists; Animals; Antihypertensive Agents; Blood Pressure; Caffeine; Carotid Arteries; Consciousness; Cytidine; Dose-Response Relationship, Drug; Heart Rate; Hypotension; Injections, Intravenous; Injections, Intraventricular; Male; Rats; Rats, Wistar; Receptor, Adenosine A1; Receptor, Adenosine A2A; Theobromine; Theophylline; Time Factors; Triazines; Triazoles; Uridine; Ventricular Function, Left; Ventricular Pressure; Xanthines | 2008 |
Caffeine and a selective adenosine A(2B) receptor antagonist but not imidazoline receptor antagonists modulate antinociception induced by diphenyl diselenide in mice.
Topics: Adrenergic alpha-Antagonists; Animals; Behavior, Animal; Benzene Derivatives; Benzofurans; Caffeine; Disease Models, Animal; Dose-Response Relationship, Drug; Hyperalgesia; Imidazoles; Injections, Intraperitoneal; Male; Mice; Neuroprotective Agents; Organoselenium Compounds; Pain Measurement; Phosphodiesterase Inhibitors; Pyrimidines; Triazoles; Xanthines | 2008 |
The effects of adenosine A2A receptor antagonists on haloperidol-induced movement disorders in primates.
Topics: Adenosine A2 Receptor Antagonists; Animals; Antipsychotic Agents; Caffeine; Catalepsy; Cebus; Corpus Striatum; Disease Models, Animal; Dose-Response Relationship, Drug; Dyskinesia, Drug-Induced; gamma-Aminobutyric Acid; Globus Pallidus; Haloperidol; Neurologic Examination; Purines; Pyrimidines; Receptor, Adenosine A2A; Saimiri; Triazoles; Xanthines | 2008 |
Neonatal caffeine induces sex-specific developmental plasticity of the hypoxic respiratory chemoreflex in adult rats.
Topics: Adrenergic alpha-2 Receptor Antagonists; Anesthesia; Animals; Animals, Newborn; Caffeine; Carotid Body; Central Nervous System Stimulants; Female; Gene Expression; Hypoxia; Male; Neural Inhibition; Phrenic Nerve; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, alpha-2; Receptors, Dopamine D2; Reflex; Respiration; RNA, Messenger; Sex Characteristics; Triazines; Triazoles; Tyrosine 3-Monooxygenase | 2008 |
Alcohol-induced retrograde memory impairment in rats: prevention by caffeine.
Topics: Adenosine A2 Receptor Antagonists; Amnesia, Retrograde; Animals; Caffeine; Central Nervous System Depressants; Central Nervous System Stimulants; Dose-Response Relationship, Drug; Drug Therapy, Combination; Ethanol; Exploratory Behavior; Habituation, Psychophysiologic; Injections, Intraperitoneal; Male; Odorants; Pentylenetetrazole; Phosphodiesterase 5 Inhibitors; Purinones; Rats; Rats, Long-Evans; Rats, Sprague-Dawley; Recognition, Psychology; Seizures; Smell; Time Factors; Triazines; Triazoles; Wood | 2008 |
Caffeine modulates TNF-alpha production by cord blood monocytes: the role of adenosine receptors.
Topics: Acetamides; Adenosine A1 Receptor Antagonists; Adenosine A2 Receptor Antagonists; Adenosine A3 Receptor Antagonists; Adult; Blotting, Western; Caffeine; Cells, Cultured; Cyclic AMP; Dose-Response Relationship, Drug; Enzyme-Linked Immunosorbent Assay; Fetal Blood; Humans; Infant, Newborn; Interleukins; Lipopolysaccharides; Middle Aged; Monocytes; Purines; Quinazolines; Receptor, Adenosine A1; Receptor, Adenosine A2A; Receptor, Adenosine A2B; Receptor, Adenosine A3; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Time Factors; Triazines; Triazoles; Tumor Necrosis Factor-alpha; Xanthines | 2009 |
Adenosine A(1) and A(2A) receptors in mouse prefrontal cortex modulate acetylcholine release and behavioral arousal.
Topics: Acetylcholine; Adenosine; Adenosine A1 Receptor Antagonists; Adenosine A2 Receptor Antagonists; Analysis of Variance; Animals; Arousal; Behavior, Animal; Caffeine; Chromatography, High Pressure Liquid; Electroencephalography; Electromyography; Male; Mice; Microdialysis; Phenethylamines; Phosphodiesterase Inhibitors; Prefrontal Cortex; Receptor, Adenosine A1; Receptors, Adenosine A2; Spectrum Analysis; Triazines; Triazoles; Xanthines | 2009 |
Caffeine and a selective adenosine A2A receptor antagonist induce reward and sensitization behavior associated with increased phospho-Thr75-DARPP-32 in mice.
Topics: Adenosine A2 Receptor Antagonists; Animals; Blotting, Western; Caffeine; Conditioning, Operant; Dopamine and cAMP-Regulated Phosphoprotein 32; Dose-Response Relationship, Drug; Male; Mice; Mice, Inbred C57BL; Neuroprotective Agents; Phosphodiesterase Inhibitors; Purinergic P1 Receptor Antagonists; Pyrimidines; Reward; Triazoles; Xanthines | 2009 |
Adenosine receptor antagonists improve short-term object-recognition ability of spontaneously hypertensive rats: a rodent model of attention-deficit hyperactivity disorder.
Topics: Adenosine A1 Receptor Antagonists; Adenosine A2 Receptor Antagonists; Animals; Attention Deficit Disorder with Hyperactivity; Blood Pressure; Caffeine; Disease Models, Animal; Female; Male; Memory, Short-Term; Methylphenidate; Rats; Rats, Inbred SHR; Rats, Wistar; Receptor, Adenosine A1; Receptors, Adenosine A2; Recognition, Psychology; Triazines; Triazoles; Xanthines | 2009 |
Adenosine antagonists reverse the cataleptic effects of haloperidol: implications for the treatment of Parkinson's disease.
Topics: Animals; Caffeine; Catalepsy; Dose-Response Relationship, Drug; Haloperidol; Male; Parkinson Disease; Purinergic P1 Receptor Antagonists; Pyrimidines; Rats; Rats, Sprague-Dawley; Triazoles | 2009 |
Adenosine receptor antagonists and behavioral activation in NF-kappaB p50 subunit knockout mice.
Topics: Adenosine A1 Receptor Antagonists; Adenosine A2 Receptor Antagonists; Administration, Oral; Animals; Behavior, Animal; Brain; Caffeine; Central Nervous System Stimulants; Chromatography, High Pressure Liquid; Dopamine; Enzyme Inhibitors; Injections, Intraperitoneal; Mice; Mice, Knockout; Motor Activity; Neuroprotective Agents; NF-kappa B p50 Subunit; Pyrimidines; Receptor, Adenosine A1; Receptor, Adenosine A2A; Receptors, Dopamine D2; Triazoles | 2009 |
Differential effects of adenosine antagonists in two models of parkinsonian tremor.
Topics: Adenosine; Adenosine A1 Receptor Antagonists; Adenosine A2 Receptor Antagonists; Animals; Caffeine; Cholinergic Agonists; Disease Models, Animal; Dopamine Antagonists; Dopamine D2 Receptor Antagonists; Drug Synergism; Jaw; Male; Parkinsonian Disorders; Pimozide; Purinergic P1 Receptor Antagonists; Pyrimidines; Rats; Rats, Sprague-Dawley; Tacrine; Theophylline; Tremor; Triazoles | 2009 |
Caffeine and an adenosine A(2A) receptor antagonist prevent memory impairment and synaptotoxicity in adult rats triggered by a convulsive episode in early life.
Topics: Adenosine A2 Receptor Antagonists; Analysis of Variance; Animals; Animals, Newborn; Caffeine; Disease Models, Animal; Disease Progression; Drug Administration Schedule; Glial Fibrillary Acidic Protein; Kainic Acid; Memory Disorders; Neurotoxicity Syndromes; Phosphodiesterase Inhibitors; Purines; Pyrimidines; Qa-SNARE Proteins; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; Seizures; Synapses; Synaptophysin; Synaptosomal-Associated Protein 25; Triazoles; Tritium; Xanthines | 2010 |
Adenosine A2A receptor blockade prevents synaptotoxicity and memory dysfunction caused by beta-amyloid peptides via p38 mitogen-activated protein kinase pathway.
Topics: Adenosine A2 Receptor Antagonists; Alzheimer Disease; Amyloid beta-Peptides; Animals; Caffeine; Cell Survival; Cells, Cultured; Down-Regulation; Male; Maze Learning; Memory Disorders; Mice; Mice, Inbred C57BL; Mice, Knockout; Nerve Degeneration; Neuroprotective Agents; p38 Mitogen-Activated Protein Kinases; Peptide Fragments; Phosphodiesterase Inhibitors; Phosphorylation; Presynaptic Terminals; Pyrimidines; Rats; Rats, Wistar; Receptor, Adenosine A2A; Synaptic Membranes; Triazoles | 2009 |
The stimulatory effects of caffeine with oseltamivir (Tamiflu) on light-dark behavior and open-field behavior in mice.
Topics: Adenosine A1 Receptor Antagonists; Adenosine A2 Receptor Antagonists; Animals; Antiviral Agents; Caffeine; Darkness; Dopamine Antagonists; Dopamine D2 Receptor Antagonists; Exploratory Behavior; Flumazenil; GABA Modulators; GABA-A Receptor Antagonists; Haloperidol; Male; Mice; Motor Activity; Neurotransmitter Agents; Oseltamivir; Pyrimidines; Random Allocation; Triazoles; Xanthines | 2010 |
Blockade of adenosine A2A receptor counteracts neuropeptide-S-induced hyperlocomotion in mice.
Topics: Adenosine A1 Receptor Antagonists; Adenosine A2 Receptor Antagonists; Animals; Caffeine; Humans; Male; Mice; Mice, Inbred Strains; Motor Activity; Neuropeptides; Triazines; Triazoles | 2010 |
Caffeine and a selective adenosine A2A receptor antagonist induce sensitization and cross-sensitization behavior associated with increased striatal dopamine in mice.
Topics: 3,4-Dihydroxyphenylacetic Acid; Adenosine A2 Receptor Antagonists; Animals; Caffeine; Dopamine; Homovanillic Acid; Male; Mice; Mice, Inbred BALB C; Neostriatum; Neuroprotective Agents; Phosphorylation; Pyrimidines; Serine; Triazoles; Tyrosine 3-Monooxygenase; Xanthines | 2010 |
Protective effect of caffeine and a selective A2A receptor antagonist on impairment of memory and oxidative stress of aged rats.
Topics: Adenosine A2 Receptor Antagonists; Aging; Animals; Ascorbic Acid; Brain; Caffeine; Male; Memory; Memory Disorders; Oxidative Stress; Pyrimidines; Rats; Rats, Wistar; Reactive Nitrogen Species; Reactive Oxygen Species; Sodium-Potassium-Exchanging ATPase; Triazoles | 2011 |
Effect of adenosine A(2A) receptor antagonists and L-DOPA on hydroxyl radical, glutamate and dopamine in the striatum of 6-OHDA-treated rats.
Topics: 3,4-Dihydroxyphenylacetic Acid; Adenosine A2 Receptor Antagonists; Animals; Benserazide; Caffeine; Dopamine; Glutamic Acid; Hydroxyl Radical; Levodopa; Male; Microdialysis; Neostriatum; Oxidopamine; Parkinsonian Disorders; Rats; Rats, Wistar; Receptor, Adenosine A2A; Triazines; Triazoles | 2012 |
Structure of the adenosine A(2A) receptor in complex with ZM241385 and the xanthines XAC and caffeine.
Topics: Adenosine A2 Receptor Agonists; Amino Acid Motifs; Amino Acid Sequence; Amino Acid Substitution; Binding Sites; Caffeine; Crystallography, X-Ray; HEK293 Cells; Humans; Hydrogen Bonding; Models, Molecular; Molecular Sequence Data; Mutagenesis, Site-Directed; Protein Binding; Protein Stability; Protein Structure, Tertiary; Receptor, Adenosine A2A; Surface Properties; Triazines; Triazoles; Xanthines | 2011 |
Computational study of the binding modes of caffeine to the adenosine A2A receptor.
Topics: Amino Acid Substitution; Caffeine; Entropy; Humans; Lipid Bilayers; Molecular Dynamics Simulation; Mutagenesis, Site-Directed; Protein Binding; Protein Structure, Tertiary; Receptor, Adenosine A2A; Triazines; Triazoles | 2011 |
The effect of adenosine A(2A) receptor antagonists on hydroxyl radical, dopamine, and glutamate in the striatum of rats with altered function of VMAT2.
Topics: 3,4-Dihydroxyphenylacetic Acid; Adenosine A2 Receptor Antagonists; Adrenergic Uptake Inhibitors; Animals; Caffeine; Corpus Striatum; Dopamine; Dopamine Agents; Extracellular Space; Glutamic Acid; Homovanillic Acid; Hydroxyl Radical; Levodopa; Male; Microdialysis; Oxidative Stress; Rats; Rats, Wistar; Reserpine; Triazines; Triazoles; Vesicular Monoamine Transport Proteins | 2012 |
Effects of ethanolic extract and naphthoquinones obtained from the bulbs of Cipura paludosa on short-term and long-term memory: involvement of adenosine A₁ and A₂A receptors.
Topics: Animals; Avoidance Learning; Brazil; Caffeine; Ethanol; Furans; Iridaceae; Male; Memory, Long-Term; Memory, Short-Term; Mice; Naphthoquinones; Plant Extracts; Plant Roots; Purinergic P1 Receptor Antagonists; Rats; Rats, Wistar; Receptor, Adenosine A1; Receptors, Adenosine A2; Triazines; Triazoles; Xanthines | 2013 |
High-intensity swimming exercise reduces neuropathic pain in an animal model of complex regional pain syndrome type I: evidence for a role of the adenosinergic system.
Topics: Adenine; Adenosine; Adenosine A1 Receptor Antagonists; Adenosine A2 Receptor Antagonists; Adenosine Deaminase Inhibitors; Animals; Caffeine; Exercise Therapy; Hyperalgesia; Male; Mice; Naloxone; Narcotic Antagonists; Neuralgia; Neurons; Reflex Sympathetic Dystrophy; Swimming; Triazines; Triazoles; Xanthines | 2013 |
Integrated control of blister blight disease in tea using the biocontrol agent Ochrobactrum anthropi strain BMO-111 with chemical fungicides.
Topics: Animals; Basidiomycota; Biological Control Agents; Caffeine; Camellia sinensis; Catechin; Copper; Fungicides, Industrial; India; Male; Mice; Ochrobactrum anthropi; Phenols; Plant Diseases; Plant Leaves; Triazoles | 2013 |
Analysis of polar organic contaminants in surface water of the northern Adriatic Sea by solid-phase extraction followed by ultrahigh-pressure liquid chromatography-QTRAP® MS using a hybrid triple-quadrupole linear ion trap instrument.
Topics: Caffeine; Chromatography, High Pressure Liquid; Equipment Design; North Sea; Oceans and Seas; Organic Chemicals; Pesticides; Pharmaceutical Preparations; Seasons; Seawater; Solid Phase Extraction; Sucrose; Triazoles; Water Pollutants, Chemical | 2013 |
Caffeine and the analog CGS 15943 inhibit cancer cell growth by targeting the phosphoinositide 3-kinase/Akt pathway.
Topics: Antineoplastic Agents; Apoptosis; Caffeine; Carcinoma, Hepatocellular; Carcinoma, Pancreatic Ductal; Cell Line, Tumor; Cell Proliferation; Humans; Liver Neoplasms; Pancreatic Neoplasms; Phosphatidylinositol 3-Kinases; Proto-Oncogene Proteins c-akt; Purinergic P1 Receptor Agonists; Quinazolines; Signal Transduction; Triazoles | 2014 |
Sensorimotor gating is disrupted by acute but not chronic systemic exposure to caffeine in mice.
Topics: Adenosine A1 Receptor Antagonists; Adenosine A2 Receptor Antagonists; Animals; Caffeine; Central Nervous System Stimulants; Male; Mice; Mice, Inbred C57BL; Prepulse Inhibition; Purinergic P1 Receptor Antagonists; Pyrimidines; Sensory Gating; Triazoles; Xanthines | 2014 |
Activating persulfate by Fe⁰ coupling with weak magnetic field: performance and mechanism.
Topics: Azo Compounds; Caffeine; Color; Diuron; Hydrogen-Ion Concentration; Iron; Kinetics; Magnetic Fields; Minerals; Nitrophenols; Sulfates; Triazoles; Water Pollutants, Chemical | 2014 |
Dual blockade of the A1 and A2A adenosine receptor prevents amyloid beta toxicity in neuroblastoma cells exposed to aluminum chloride.
Topics: Adenosine A1 Receptor Antagonists; Adenosine A2 Receptor Antagonists; Aluminum Chloride; Aluminum Compounds; Amyloid beta-Peptides; Apoptosis; Astringents; Blotting, Western; Caffeine; Cell Proliferation; Cells, Cultured; Chlorides; Humans; Lipid Peroxidation; Neuroblastoma; Neuroprotective Agents; Oxidative Stress; Purinergic P1 Receptor Antagonists; Pyrimidines; Reactive Oxygen Species; Receptor, Adenosine A1; Receptor, Adenosine A2A; RNA, Small Interfering; Triazoles; Xanthines | 2014 |
Distinct pro-vigilant profile induced in rats by the mGluR5 potentiator LSN2814617.
Topics: Animals; Arousal; Benzhydryl Compounds; Biofeedback, Psychology; Caffeine; Central Nervous System Stimulants; Conditioning, Operant; Dextroamphetamine; Electroencephalography; Excitatory Amino Acid Agonists; Male; Modafinil; Oxadiazoles; Psychomotor Performance; Pyridines; Rats; Rats, Wistar; Reaction Time; Receptor, Metabotropic Glutamate 5; Sleep; Sleep Deprivation; Sleep, REM; Triazoles | 2015 |
Effect of adenosine system in the action of oseltamivir on behavior in mice.
Topics: Adenosine; Adenosine A1 Receptor Antagonists; Adenosine A2 Receptor Agonists; Adenosine A2 Receptor Antagonists; Animals; Antiviral Agents; Behavior, Animal; Caffeine; Dose-Response Relationship, Drug; Drug Interactions; Male; Mice; Neuraminidase; Oseltamivir; Phenethylamines; Pyrimidines; Receptors, Adenosine A2; Triazoles; Walking | 2015 |
Caffeine promotes anti-tumor immune response during tumor initiation: Involvement of the adenosine A2A receptor.
Topics: Adenosine A2 Receptor Antagonists; Animals; Caffeine; Cell Line, Tumor; Cyclopentanes; Fibrosarcoma; Mice; Mice, Knockout; Neoplasms, Experimental; Receptor, Adenosine A2A; Triazines; Triazoles | 2015 |
Caffeine Suppresses the Activation of Hepatic Stellate Cells cAMP-Independently by Antagonizing Adenosine Receptors.
Topics: Animals; Caffeine; Cells, Cultured; Chelating Agents; Cyclic AMP; Dose-Response Relationship, Drug; Egtazic Acid; Hepatic Stellate Cells; Liver Cirrhosis; Male; MAP Kinase Signaling System; Mice; Phosphodiesterase Inhibitors; Phosphorylation; Quinazolines; Receptors, Purinergic P1; Triazoles | 2017 |
Caffeine accelerates recovery from general anesthesia via multiple pathways.
Topics: Adenosine A2 Receptor Antagonists; Anesthesia, General; Anesthetics, General; Animals; Brain; Caffeine; Central Nervous System Stimulants; Colforsin; Cyclic AMP; Delayed Emergence from Anesthesia; Isoflurane; Pyrimidines; Rats; Rats, Sprague-Dawley; Triazoles | 2017 |
Theacrine: A purine alkaloid from Camellia assamica var. kucha with a hypnotic property via the adenosine system.
Topics: Adenosine; Alkaloids; Animals; Caffeine; Camellia; Drug Synergism; Hippocampus; Male; Mice; Pentobarbital; Pyrimidines; Rats; Sleep Initiation and Maintenance Disorders; Sleep Stages; Triazoles; Uric Acid; Xanthines | 2017 |
Preemptive Caffeine Administration Blocks the Increase in Postoperative Pain Caused by Previous Sleep Loss in the Rat: A Potential Role for Preoptic Adenosine A2A Receptors in Sleep-Pain Interactions.
Topics: Adenosine A2 Receptor Antagonists; Animals; Caffeine; Female; Hyperalgesia; Male; Pain, Postoperative; Preoptic Area; Rats; Rats, Sprague-Dawley; Receptor, Adenosine A2A; Sex Characteristics; Sleep; Sleep Deprivation; Triazines; Triazoles | 2017 |
Effects of caffeine and phosphodiesterase inhibitors on activation of neonatal T lymphocytes.
Topics: Adenosine A2 Receptor Antagonists; Adult; Aging; Caffeine; Calcium Signaling; Cells, Cultured; Cyclic AMP; Cytokines; Female; Humans; Infant, Newborn; Leukocytes, Mononuclear; Lymphocyte Activation; Male; Milrinone; Phosphodiesterase Inhibitors; Reactive Oxygen Species; Sildenafil Citrate; T-Lymphocytes; Triazines; Triazoles | 2018 |
Caffeine Exacerbates Postictal Hypoxia.
Topics: Adenosine; Animals; CA1 Region, Hippocampal; Caffeine; Dose-Response Relationship, Drug; Hypoxia; Kindling, Neurologic; Male; Oxygen; Phenethylamines; Pyrimidines; Rats; Receptors, Adenosine A2; Seizures; Triazoles | 2019 |
Prolonged caffeine intake decreases alveolar bone damage induced by binge-like ethanol consumption in adolescent female rats.
Topics: Adenosine A2 Receptor Antagonists; Alveolar Bone Loss; Animals; Binge Drinking; Bone Density; Caffeine; Ethanol; Female; Neuroprotective Agents; Periodontitis; Pyrimidines; Rats; Rats, Wistar; Triazoles; X-Ray Microtomography | 2020 |
Design, synthesis, and structure-activity relationship of caffeine-based triazoles as dual AChE and BACE-1 inhibitors.
Topics: Acetylcholinesterase; Alzheimer Disease; Biological Products; Caffeine; Cholinesterase Inhibitors; Humans; Molecular Docking Simulation; Molecular Structure; Structure-Activity Relationship; Triazoles | 2022 |