triazoles has been researched along with bn 50730 in 48 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 42 (87.50) | 18.2507 |
| 2000's | 5 (10.42) | 29.6817 |
| 2010's | 1 (2.08) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Bonhomme, B; Braquet, P; Doly, M; Droy-Lefaix, MT; Millerin, M | 1 |
| Mayeux, PR; Shah, SV; Ueda, N; Walker, PD | 1 |
| Braquet, P; Esanu, A; Hosford, D; Laurent, JP; Martin, C; Pommier, J; Rolland, A | 1 |
| Bonne, C; Meynier, F; Muller, A | 1 |
| Braquet, P; Friedrich, G; Giessler, J; Hirschelmann, R; Madi, S | 1 |
| Braquet, P; Esanu, A | 1 |
| Beckerman, RC; Bellan, JA; Braquet, P; Dyson, MC; Kadowitz, PJ; McNamara, DB; Minkes, RK; Wegmann, MJ | 1 |
| Abacioğlu, N; Cakici, I; Ersoy, S; Kanzik, I; Mataraci, N; Tunçtan, B | 1 |
| Bonhomme, B; Braquet, P; Cluzel, J; Doly, M; Millerin, M | 2 |
| Braquet, P; Dobozy, A; Duda, E; Hunyadi, J; Kenderessy, AS | 1 |
| Aissa, J; Arnoux, B; Benveniste, J; Guinot, P; Hilliquin, P; Laoussadi, S; Menkes, CJ; Natour, J | 1 |
| Guinot, P | 1 |
| Diserbo, M; Fatome, M; Lalouette, F; Martin, C; Verdetti, J | 1 |
| Fourtillan, JB; Girault, J; Lecomte, G; Longueville, D; Malgouyat, JM; Revaud, M | 1 |
| Bozza, PT; Braquet, P; Castro-Faria-Neto, HC; Cordeiro, RS; e Silva, PM; Lagente, V; Martins, MA; Pasquale, C; Pires, AL; Rae, GA | 1 |
| Celma, C | 1 |
| Baskin, DG; Braquet, P; Goodner, CJ; Jobe, LW; Lernmark, A; Ubungen, R | 1 |
| Bazan, NG; Clark, GD; Kato, K; Zorumski, CF | 1 |
| Bazan, NG; Marcheselli, VL | 1 |
| Bazan, HE; Bazan, NG; Tao, Y | 2 |
| Boichot, E; Braquet, P; Lagente, V; Mencia-Huerta, JM | 1 |
| Chermat-Izard, V; Guinot, P; Hilliquin, P; Menkes, CJ; Puechal, X | 1 |
| Boichot, E; Braquet, P; Kyriacopoulos, F; Lagente, V; Mencia-Huerta, JM | 1 |
| Bazan, HE; Hurst, JS | 1 |
| Cordeiro, RS; Cruz, HN; Martins, MA; Noël, F; Silva, CL; Violante, FA | 1 |
| Bindoni, M; Cardile, V; Jiang, X; Renis, M | 1 |
| Bindoni, M; Cardile, V; De Simoni, MG; Jiang, X; Mascarucci, P | 1 |
| Cluzel, J; Doly, M; Droy-Lefaix, MT; Menerath, JM | 1 |
| Bazan, HE; Varner, L | 1 |
| Bagby, GJ; Giles, TD; Greenberg, SS; Joseph, KO; Xie, J | 1 |
| Bazan, HE; Bazan, NG; DeCoster, MA; Tao, Y | 1 |
| Bernasconi, S; Dejana, E; Del Maschio, A; Martín-Padura, I | 1 |
| Sharma, A; Singh, M; Singh, N | 2 |
| Bazan, NG; Davis, RJ; DeCoster, MA; Mukherjee, PK | 1 |
| Chermat-Izard, V; Hilliquin, P; Menkes, CJ | 1 |
| Bazan, NG; Campbell, FZ; Davis, RJ; DeCoster, MA; Mukherjee, PK | 1 |
| Egido, J; Gutierrez, S; Herrero-Beaumont, G; Miguélez, R; Palacios, I; Sánchez-Pernaute, O | 1 |
| Bazan, NG; DeCoster, MA; Serou, MJ | 1 |
| Boichot, E; Braquet, P; Carre, C; Guinot, P; Lagente, V; Mencia-Huerta, JM | 1 |
| Sun, GY; Wang, JH | 1 |
| Barks, JD; Eun, BL; Liu, XH | 1 |
| Gokorsch, S; Grimminger, F; Krüll, M; Lohmeyer, J; Mayer, K; Merfels, M; Muhly-Reinholz, M; Rosseau, S; Schwarzer, N; Seeger, W; Suttorp, N | 1 |
| Magnusson, JE; Teather, LA; Wurtman, RJ | 1 |
| Bazan, HE; Bazan, NG; Ma, X; Ottino, P | 1 |
| Borgeat, P; Flamand, N; Lefebvre, JS; Lévesque, T; Marleau, S; Milot, V; Picard, S | 1 |
4 review(s) available for triazoles and bn 50730
| Article | Year |
|---|---|
From ginkgolides to N-substituted piperidino-thieno diazepines, a new series of highly potent dual antagonists.
Topics: Animals; Azepines; Diterpenes; Ginkgolides; Humans; Lactones; Piperidines; Plant Extracts; Platelet Activating Factor; Tetrazoles; Thienopyridines; Triazoles | 1991 |
New trends in PAF antagonist research: a new series of potent hetrapazine-derived PAF antagonists.
Topics: Animals; Azepines; Platelet Activating Factor; Tetrazoles; Thienopyridines; Triazoles | 1991 |
Clinical experience with platelet-activating factor antagonists. Past, present, and near future.
Topics: Animals; Azepines; Clinical Trials as Topic; Graft Rejection; Humans; Kidney Transplantation; Lactones; Plant Extracts; Platelet Activating Factor; Randomized Controlled Trials as Topic; Shock, Septic; Thienopyridines; Triazoles | 1994 |
Activation of the phospholipase/cyclooxygenase cascade in the rabbit cornea by platelet-activating factor is challenged by PAF receptor antagonists.
Topics: Animals; Arachidonic Acid; Azepines; Cornea; Enzyme Activation; Phospholipases; Platelet Activating Factor; Platelet Membrane Glycoproteins; Prostaglandin-Endoperoxide Synthases; Rabbits; Receptors, Cell Surface; Receptors, G-Protein-Coupled; Thienopyridines; Triazoles | 1995 |
2 trial(s) available for triazoles and bn 50730
| Article | Year |
|---|---|
Treatment of rheumatoid arthritis with platelet activating factor antagonist BN 50730.
Topics: Adult; Aged; Arthritis, Rheumatoid; Azepines; Female; Humans; Male; Middle Aged; Platelet Aggregation Inhibitors; Severity of Illness Index; Thienopyridines; Treatment Outcome; Triazoles | 1995 |
A double blind, placebo controlled study of a platelet activating factor antagonist in patients with rheumatoid arthritis.
Topics: Adult; Aged; Antirheumatic Agents; Arthritis, Rheumatoid; Azepines; Double-Blind Method; Female; Humans; Male; Middle Aged; Outcome Assessment, Health Care; Platelet Activating Factor; Platelet Aggregation Inhibitors; Thienopyridines; Treatment Outcome; Triazoles | 1998 |
42 other study(ies) available for triazoles and bn 50730
| Article | Year |
|---|---|
Inhibition of vincristine-induced retinal impairments by a specific PAF antagonist.
Topics: Animals; Azepines; Electroretinography; Organ Culture Techniques; Perfusion; Photic Stimulation; Platelet Activating Factor; Rats; Rats, Sprague-Dawley; Retinal Diseases; Tetrazoles; Thienopyridines; Triazoles; Vincristine | 1992 |
Receptor-mediated increase in cytosolic calcium in LLC-PK1 cells by platelet activating factor and thromboxane A2.
Topics: Animals; Azepines; Calcium; Carbazoles; Cell Line; Cytosol; Kidney Tubules, Proximal; Platelet Activating Factor; Platelet Membrane Glycoproteins; Receptors, Cell Surface; Receptors, G-Protein-Coupled; Receptors, Prostaglandin; Receptors, Thromboxane; Tetrazoles; Thienopyridines; Thromboxane A2; Triazoles | 1991 |
PAF-induced conjunctivitis in the rabbit is mediated by peptido-leukotrienes.
Topics: Animals; Azepines; Conjunctiva; Conjunctivitis; Cyclooxygenase Inhibitors; Dicarboxylic Acids; Evans Blue; Extravasation of Diagnostic and Therapeutic Materials; Indomethacin; Leukotriene B4; Leukotrienes; Lipoxygenase Inhibitors; Male; Platelet Activating Factor; Rabbits; Second Messenger Systems; Tetrazoles; Thiazoles; Thienopyridines; Triazoles | 1990 |
Allergen-induced bronchospasm in passively sensitized guinea pigs: influence of new substances in comparison to reference compounds.
Topics: Acrylates; Allergens; Animals; Azepines; Benzoates; Bronchial Spasm; Disease Models, Animal; Guinea Pigs; Immunization, Passive; Male; Ovalbumin; Phospholipases A; Platelet Activating Factor; Tetrazoles; Thienopyridines; Triazoles | 1991 |
Influence of SK&F 95587 and BN 50730 on bronchoconstrictor responses in the cat.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Animals; Azepines; Bronchoconstriction; Cats; Dose-Response Relationship, Drug; Female; Lung; Male; Platelet Activating Factor; Platelet Aggregation Inhibitors; Platelet Membrane Glycoproteins; Prostaglandin Endoperoxides, Synthetic; Receptors, Cell Surface; Receptors, G-Protein-Coupled; Receptors, Prostaglandin; Receptors, Thromboxane; Respiration; Sulfonamides; Tetrazoles; Thienopyridines; Time Factors; Triazoles | 1990 |
Effects of platelet-activating factor antagonists WEB 2086 and BN 50730 on digoxin-induced arrhythmias.
Topics: Animals; Arrhythmias, Cardiac; Azepines; Digoxin; Female; Guinea Pigs; Hemodynamics; Male; Platelet Activating Factor; Platelet Aggregation Inhibitors; Thienopyridines; Triazoles | 1995 |
Protective effect of a specific PAF antagonist on vincristine-induced experimental retinopathy.
Topics: Animals; Azepines; Dark Adaptation; Electroretinography; Platelet Activating Factor; Rats; Rats, Sprague-Dawley; Retina; Retinal Diseases; Thienopyridines; Triazoles; Vincristine | 1995 |
Platelet-activating factor antagonists (BN 52021 and BN 50730) inhibit tumor necrosis factor-alfa-mediated cytotoxicity on murine L929 tumor cells.
Topics: Animals; Aprotinin; Azepines; Cytotoxicity, Immunologic; Diterpenes; Dose-Response Relationship, Immunologic; Ginkgolides; Lactones; Mice; Platelet Activating Factor; Tetrazoles; Thienopyridines; Triazoles; Tumor Cells, Cultured; Tumor Necrosis Factor-alpha | 1993 |
Treatment of carrageenan induced arthritis by the platelet activating factor antagonist BN 50730.
Topics: Animals; Arthritis, Experimental; Azepines; Carrageenan; Injections, Intra-Articular; Platelet Activating Factor; Rabbits; Thienopyridines; Triazoles | 1995 |
Presence of specific platelet-activating factor binding-sites in neuroblastoma N1E-115 cells.
Topics: Animals; Azepines; Binding Sites; Binding, Competitive; Brain Neoplasms; Diterpenes; Ginkgolides; Kinetics; Lactones; Mice; Neuroblastoma; Platelet Activating Factor; Platelet Membrane Glycoproteins; Receptors, Cell Surface; Receptors, G-Protein-Coupled; Thienopyridines; Triazoles; Tumor Cells, Cultured | 1995 |
Quantitative measurement of a new synthetic hetrazepine derivative, BN50730, in human plasma and urine by combined liquid chromatography-negative chemical ionization mass spectrometry using a particle beam interface.
Topics: Adult; Azepines; Chromatography, High Pressure Liquid; Humans; Indicators and Reagents; Male; Mass Spectrometry; Platelet Activating Factor; Quality Control; Spectrophotometry, Ultraviolet; Thienopyridines; Triazoles | 1994 |
Long-lasting inhibitory activity of the hetrazepinic BN 50730 on exudation and cellular alterations evoked by PAF and LPS.
Topics: Animals; Azepines; Cell Movement; Chemotaxis, Leukocyte; Exudates and Transudates; Female; Leukocytes; Lipopolysaccharides; Male; Platelet Activating Factor; Platelet Aggregation; Rabbits; Rats; Rats, Wistar; Thienopyridines; Triazoles | 1994 |
Determination of the platelet activating factor antagonist 6-(2- chlorophenyl)-9-[(4-methoxyphenyl)thiocarbamoyl]-1-methyl-7,8,9,10- tetrahydro-4H-pyrido[4',3'-4,5]-thieno[3,2-f][1,2,4]triazolo[4, 3-a][1,4] diazepine in human plasma by liquid chromatograp
Topics: Azepines; Chromatography, High Pressure Liquid; Chromatography, Ion Exchange; Humans; Mass Spectrometry; Microchemistry; Platelet Activating Factor; Quality Control; Sensitivity and Specificity; Thienopyridines; Triazoles | 1994 |
Protection from BB rat diabetes by the platelet-activating factor inhibitor BN50730.
Topics: Age Factors; Animals; Autoimmune Diseases; Azepines; Diabetes Mellitus, Type 1; Insulin; Islets of Langerhans; Male; Platelet Activating Factor; Rats; Rats, Inbred BB; Tetrazoles; Thienopyridines; Thyroid Gland; Thyroiditis, Autoimmune; Triazoles | 1993 |
Platelet-activating factor as a potential retrograde messenger in CA1 hippocampal long-term potentiation.
Topics: Action Potentials; Animals; Azepines; Diterpenes; Ginkgolides; Hippocampus; In Vitro Techniques; Lactones; Long-Term Potentiation; Male; Phospholipid Ethers; Platelet Activating Factor; Platelet Membrane Glycoproteins; Rats; Receptors, Cell Surface; Receptors, G-Protein-Coupled; Tetrazoles; Thienopyridines; Triazoles | 1994 |
Platelet-activating factor is a messenger in the electroconvulsive shock-induced transcriptional activation of c-fos and zif-268 in hippocampus.
Topics: Animals; Azepines; Base Sequence; DNA-Binding Proteins; Early Growth Response Protein 1; Electroshock; Gene Expression Regulation; Hippocampus; Immediate-Early Proteins; Male; Microsomes; Molecular Sequence Data; Neuronal Plasticity; Platelet Activating Factor; Platelet Membrane Glycoproteins; Proto-Oncogene Proteins c-fos; Rats; Rats, Wistar; Receptors, Cell Surface; Receptors, G-Protein-Coupled; Seizures; Synaptic Membranes; Tetrazoles; Thienopyridines; Transcription Factors; Transcription, Genetic; Triazoles; Zinc Fingers | 1994 |
Prevention of chloroquine-induced electroretinographic damage by a new platelet-activating factor antagonist, BN 50730.
Topics: Animals; Azepines; Chloroquine; Dark Adaptation; Electroretinography; Platelet Activating Factor; Rats; Rats, Sprague-Dawley; Retina; Retinal Diseases; Tetrazoles; Thienopyridines; Triazoles | 1993 |
Platelet-activating factor induces collagenase expression in corneal epithelial cells.
Topics: Animals; Azepines; Base Sequence; Blotting, Northern; Collagenases; Cornea; Cycloheximide; Epithelium; Gene Expression; Genes, fos; Genes, jun; Kinetics; Molecular Sequence Data; Oligodeoxyribonucleotides; Organ Culture Techniques; Platelet Activating Factor; Rabbits; RNA, Messenger; Tetrazoles; Thienopyridines; Triazoles | 1993 |
Bronchopulmonary responses to endothelin-1 in sensitized and challenged guinea-pigs: role of cyclooxygenase metabolites and platelet-activating factor.
Topics: Aerosols; Animals; Azepines; Bronchi; Disease Models, Animal; Endothelins; Glycopeptides; Guinea Pigs; Immunization; Indomethacin; Lung; Male; Neprilysin; Ovalbumin; Platelet Activating Factor; Prostaglandin-Endoperoxide Synthases; Respiratory Function Tests; Tetrazoles; Thienopyridines; Time Factors; Triazoles | 1993 |
Role of PAF in the late airway microvascular leakage induced by antigen in IgE-sensitized rat.
Topics: Administration, Oral; Animals; Antigens; Azepines; Bronchi; Capillary Permeability; Evans Blue; Extravasation of Diagnostic and Therapeutic Materials; Immunoglobulin E; Injections, Intravenous; Male; Methysergide; Platelet Activating Factor; Platelet Aggregation Inhibitors; Rats; Rats, Sprague-Dawley; Serotonin; Serotonin Antagonists; Specific Pathogen-Free Organisms; Thienopyridines; Trachea; Triazoles | 1995 |
Formation of a highly stable complex between BN 50730 [tetrahydro-4,7,8,10 methyl-1(chloro-2 phenyl)-6 (methoxy-4 phenyl-carbamoyl)-9 pyrido [4',3'-4,5] thieno [3,2-f] triazolo-1,2,4 [4,3-a] diazepine-1,4] and the platelet-activating factor receptor in ra
Topics: Animals; Azepines; Binding Sites; Blood Platelets; Cell Membrane; Platelet Activating Factor; Platelet Aggregation Inhibitors; Platelet Membrane Glycoproteins; Rabbits; Receptors, Cell Surface; Receptors, G-Protein-Coupled; Thienopyridines; Triazoles | 1996 |
Effects of ether lipid 1-O-octadecyl-2-methoxy-rac-glycero- 3-phosphocholine and its analogs PAF and CPAF on the release of nitric oxide in primary cultures of rat astrocytes.
Topics: Animals; Antineoplastic Agents; Astrocytes; Azepines; Cells, Cultured; Citrulline; Enzyme Inhibitors; Glial Fibrillary Acidic Protein; Immunohistochemistry; Lipopolysaccharides; Nitric Oxide; Nitric Oxide Synthase; omega-N-Methylarginine; Phospholipid Ethers; Platelet Activating Factor; Platelet Aggregation Inhibitors; Rats; Rats, Wistar; Stimulation, Chemical; Thienopyridines; Triazoles | 1996 |
Platelet-activating factor enhances urokinase-type plasminogen activator gene expression in corneal epithelium.
Topics: Amanitins; Animals; Azepines; Blotting, Northern; Cornea; Cyclic AMP; Dactinomycin; Epithelium; Ethers, Cyclic; Gene Expression Regulation, Enzymologic; GTP-Binding Proteins; Okadaic Acid; Organ Culture Techniques; Platelet Activating Factor; Platelet Aggregation Inhibitors; Protein Synthesis Inhibitors; Rabbits; RNA, Messenger; Thienopyridines; Transcription, Genetic; Transcriptional Activation; Triazoles; Urokinase-Type Plasminogen Activator | 1996 |
The effect of ether lipid 1-O-octadecyl-2-O-methoxy-rac-glycero-3-phosphocholine and its analogues platelet activating factor and carbamyl-platelet activating factor on the biosynthesis of interleukin-6 in human thymic epithelial cells cultivated in vitro
Topics: Azepines; Cells, Cultured; Dose-Response Relationship, Drug; Epithelium; Humans; Interleukin-6; Phospholipid Ethers; Platelet Activating Factor; Platelet Membrane Glycoproteins; Receptors, Cell Surface; Receptors, G-Protein-Coupled; Thienopyridines; Thymus Gland; Triazoles | 1996 |
Experimental electroretinographic exploration of retinal ischemia: preventive use of free radical scavengers and anti-PAF agents.
Topics: Analysis of Variance; Animals; Azepines; Dark Adaptation; Disease Models, Animal; Electroretinography; Free Radical Scavengers; Ginkgo biloba; Ischemia; Plant Extracts; Platelet Aggregation Inhibitors; Random Allocation; Rats; Rats, Sprague-Dawley; Retinal Diseases; Thienopyridines; Triazoles | 1997 |
A mitogen-activated protein kinase (MAP-kinase) cascade is stimulated by platelet activating factor (PAF) in corneal epithelium.
Topics: Animals; Azepines; Calcium-Calmodulin-Dependent Protein Kinases; Chromatography, DEAE-Cellulose; Cornea; Enzyme Activation; Epithelium; MAP Kinase Kinase 1; MAP Kinase Kinase 2; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase Kinases; Platelet Activating Factor; Platelet Aggregation Inhibitors; Protein Serine-Threonine Kinases; Protein-Tyrosine Kinases; Rabbits; Stimulation, Chemical; Thienopyridines; Triazoles | 1997 |
Dissociation of TNF-alpha from endotoxin-induced nitric oxide and acute-phase hypotension.
Topics: Animals; Azepines; Blood Pressure; Endotoxins; Enzyme Induction; Escherichia coli; Heart Rate; Hypotension; Immunoglobulin G; Lipopolysaccharides; Male; Mesenteric Arteries; Muscle, Smooth, Vascular; Neutrophils; Nitric Oxide; Nitric Oxide Synthase; Platelet Activating Factor; Platelet Aggregation Inhibitors; Rats; Rats, Sprague-Dawley; RNA, Messenger; Thienopyridines; Time Factors; Transcription, Genetic; Triazoles; Tumor Necrosis Factor-alpha | 1997 |
Platelet-activating factor induces cyclooxygenase-2 gene expression in corneal epithelium. Requirement of calcium in the signal transduction pathway.
Topics: Aniline Compounds; Animals; Azepines; Blotting, Northern; Blotting, Western; Calcimycin; Calcium; Cyclooxygenase 2; Enzyme Induction; Epithelium, Corneal; Fluorescent Dyes; Gene Expression; Ionophores; Isoenzymes; Microscopy, Confocal; Organ Culture Techniques; Peroxidases; Platelet Activating Factor; Prostaglandin-Endoperoxide Synthases; Rabbits; RNA, Messenger; Signal Transduction; Thienopyridines; Triazoles; Xanthenes | 1997 |
Triggering of beta 1-integrin chain induces platelet adhesion to cultured endothelium.
Topics: Alprostadil; Animals; Antibodies, Monoclonal; Aspirin; Azepines; Blood Platelets; Cells, Cultured; Cyclic AMP; Cyclic GMP; Endothelium, Vascular; Enzyme Inhibitors; Extracellular Matrix Proteins; Humans; Integrin beta1; Mice; Mice, Inbred BALB C; Nitroprusside; P-Selectin; Platelet Adhesiveness; Platelet Membrane Glycoproteins; Protein Kinase C; Receptors, Cell Surface; Receptors, G-Protein-Coupled; Serotonin; Staurosporine; Thienopyridines; Triazoles | 1997 |
Possible mechanism of alprazolam-induced amnesia in mice.
Topics: Alprazolam; Amnesia; Animals; Azepines; Drug Evaluation, Preclinical; Female; Flumazenil; GABA Agonists; Male; Maze Learning; Mice; Platelet Activating Factor; Platelet Membrane Glycoproteins; Receptors, Cell Surface; Receptors, G-Protein-Coupled; Thienopyridines; Triazoles | 1998 |
Effects of BN-50730 (PAF receptor antagonist) and physostigmine (AChE inhibitor) on learning and memory in mice.
Topics: Acetylcholine; Amnesia, Retrograde; Animals; Azepines; Cholinesterase Inhibitors; Dose-Response Relationship, Drug; Drug Interactions; Female; Male; Maze Learning; Memory; Mice; Physostigmine; Platelet Aggregation Inhibitors; Thienopyridines; Triazoles | 1997 |
Platelet-activating factor is a downstream messenger of kainate-induced activation of mitogen-activated protein kinases in primary hippocampal neurons.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Astrocytes; Azepines; Calcium-Calmodulin-Dependent Protein Kinases; Cell Survival; Cells, Cultured; Enzyme Activation; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Hippocampus; JNK Mitogen-Activated Protein Kinases; Kainic Acid; MAP Kinase Kinase 4; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinase Kinases; Mitogen-Activated Protein Kinases; Neuronal Plasticity; Neurons; p38 Mitogen-Activated Protein Kinases; Platelet Activating Factor; Platelet Aggregation Inhibitors; Platelet Membrane Glycoproteins; Protein Kinases; Rats; Receptors, Cell Surface; Receptors, G-Protein-Coupled; Thienopyridines; Triazoles | 1998 |
Glutamate receptor signaling interplay modulates stress-sensitive mitogen-activated protein kinases and neuronal cell death.
Topics: 1-Alkyl-2-acetylglycerophosphocholine Esterase; Animals; Azepines; Calcium-Calmodulin-Dependent Protein Kinases; Cell Death; Hippocampus; Neurons; Phospholipases A; Platelet Activating Factor; Platelet Aggregation Inhibitors; Rats; Receptors, N-Methyl-D-Aspartate; Recombinant Proteins; Second Messenger Systems; Signal Transduction; Thienopyridines; Triazoles | 1999 |
A platelet activating factor receptor antagonist prevents the development of chronic arthritis in mice.
Topics: Animals; Arthritis, Rheumatoid; Azepines; Collagen; Disease Models, Animal; Female; Fibronectins; Immunohistochemistry; Joints; Mice; Mice, Inbred DBA; Platelet Aggregation Inhibitors; Platelet Membrane Glycoproteins; Receptors, Cell Surface; Receptors, G-Protein-Coupled; Thienopyridines; Triazoles | 1999 |
Interleukin-1 beta activates expression of cyclooxygenase-2 and inducible nitric oxide synthase in primary hippocampal neuronal culture: platelet-activating factor as a preferential mediator of cyclooxygenase-2 expression.
Topics: Animals; Azepines; Cyclooxygenase 2; Enzyme Induction; Hippocampus; Interleukin-1; Isoenzymes; Mice; Neurons; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Platelet Activating Factor; Platelet Aggregation Inhibitors; Prostaglandin-Endoperoxide Synthases; Rats; Recombinant Proteins; Thienopyridines; Triazoles | 1999 |
Effects of the platelet activating factor antagonists BN 52021 and BN 50730 on antigen-induced bronchial hyperresponsiveness and eosinophil infiltration in lung from sensitized guinea-pigs.
Topics: Acetylcholine; Aerosols; Animals; Azepines; Bronchial Hyperreactivity; Bronchial Provocation Tests; Bronchoalveolar Lavage Fluid; Bronchoconstrictor Agents; Diterpenes; Eosinophilia; Ginkgo biloba; Ginkgolides; Guinea Pigs; Lactones; Leukotriene B4; Lung Diseases; Male; Molecular Structure; Ovalbumin; Plants, Medicinal; Platelet Activating Factor; Specific Pathogen-Free Organisms; Thienopyridines; Triazoles | 1993 |
Platelet activating factor (PAF) antagonists on cytokine induction of iNOS and sPLA2 in immortalized astrocytes (DITNC).
Topics: Animals; Astrocytes; Azepines; Cell Line, Transformed; Cytokines; Diterpenes; Enzyme Induction; Gene Expression Regulation, Enzymologic; Ginkgolides; Group II Phospholipases A2; Interferon-gamma; Interleukin-1; Lactones; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Phospholipases A; Phospholipases A2; Platelet Activating Factor; Reverse Transcriptase Polymerase Chain Reaction; Signal Transduction; Thienopyridines; Triazoles; Tumor Necrosis Factor-alpha | 2000 |
Platelet-activating factor antagonist BN 50730 attenuates hypoxic-ischemic brain injury in neonatal rats.
Topics: Animals; Animals, Newborn; Azepines; Brain Injuries; Brain Ischemia; Cerebral Cortex; Corpus Striatum; Hippocampus; Hypoxia, Brain; Learning; Memory; Platelet Activating Factor; Rats; Rats, Sprague-Dawley; Thienopyridines; Triazoles | 2001 |
Omega-3 fatty acids suppress monocyte adhesion to human endothelial cells: role of endothelial PAF generation.
Topics: Azepines; Cell Adhesion; Cells, Cultured; Endothelium, Vascular; Fatty Acids, Omega-3; Humans; Intercellular Adhesion Molecule-1; Monocytes; Phospholipid Ethers; Platelet Activating Factor; Platelet Aggregation Inhibitors; Platelet Membrane Glycoproteins; Pyridinium Compounds; Receptors, Cell Surface; Receptors, G-Protein-Coupled; Thienopyridines; Triazoles; Tumor Necrosis Factor-alpha; Vascular Cell Adhesion Molecule-1 | 2002 |
Platelet-activating factor antagonists decrease the inflammatory nociceptive response in rats.
Topics: Animals; Azepines; Diterpenes; Dose-Response Relationship, Drug; Formaldehyde; Ginkgolides; Inflammation; Lactones; Male; Pain; Platelet Activating Factor; Platelet Aggregation Inhibitors; Rats; Rats, Sprague-Dawley; Thienopyridines; Time Factors; Triazoles | 2002 |
Platelet-activating factor (PAF) induces corneal neovascularization and upregulates VEGF expression in endothelial cells.
Topics: Animals; Antibodies; Azepines; Cattle; Cell Division; Cell Movement; Cells, Cultured; Corneal Neovascularization; Dose-Response Relationship, Drug; Endothelial Cells; Fibroblast Growth Factor 2; Humans; Mice; Mice, Inbred C57BL; Mice, Knockout; Microcirculation; Phospholipid Ethers; Platelet Activating Factor; Platelet Membrane Glycoproteins; Receptors, G-Protein-Coupled; RNA, Messenger; Skin; Thienopyridines; Triazoles; Umbilical Veins; Up-Regulation; Vascular Endothelial Growth Factor A | 2004 |
Toll-like receptor ligands induce polymorphonuclear leukocyte migration: key roles for leukotriene B4 and platelet-activating factor.
Topics: Animals; Azepines; Cell Movement; Dihydropyridines; Female; Flagellin; Humans; Imidazoles; Leukotriene B4; Ligands; Mice; Mice, Inbred C57BL; Neutrophils; Platelet Activating Factor; Poly I-C; Propionates; Quinolines; Thienopyridines; Toll-Like Receptors; Triazoles | 2010 |