triazoles has been researched along with bms-626529 in 14 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 12 (85.71) | 24.3611 |
| 2020's | 2 (14.29) | 2.80 |
| Authors | Studies |
|---|---|
| Ait-Arkoub, Z; Calvez, V; Fofana, DB; Fourati, S; Katlama, C; Lambert-Niclot, S; Marcelin, AG; Sayon, S; Simon, A; Soulié, C | 1 |
| Hanna, GJ; Healy, MD; Hwang, C; Krystal, M; Lataillade, M; Ray, N; Whitcomb, J; Wind-Rotolo, M | 1 |
| Hanna, GJ; Krystal, M; Lataillade, M; Li, Z; Ray, N; Sun, Y; Zhou, N | 1 |
| Eggers, B; Fan, L; Fang, H; Hanna, GJ; Healy, M; Hwang, C; Krystal, M; Langley, DR; Lataillade, M; McAuliffe, B; Nowicka-Sans, B; Ray, N; Zhou, N | 1 |
| Calvez, V; Charpentier, C; Descamps, D; Désiré, N; Fofana, DB; Katlama, C; Lambert-Niclot, S; Maïga, AI; Marcelin, AG; Sayon, S; Simon, A; Soulié, C; Yazdanpanah, Y | 1 |
| Dicker, I; Kadow, JF; Kimura, SR; Krystal, M; Langley, DR; McAuliffe, B; Meanwell, NA; Sivaprakasam, P; Wang, T; Zhou, N | 1 |
| Bertz, R; Furlong, M; Hanna, GJ; Hruska, M; Hwang, C; Landry, IS; Shah, V; Zhu, L | 1 |
| Abu Tarif, M; Bertz, RJ; Boulton, DW; Hanna, GJ; Hruska, M; Joshi, S; Landry, I; Lataillade, M; Pitsiu, M; Sadler, BM; Zhu, L | 1 |
| Bailer, RT; Bylund, T; Chuang, GY; Druz, A; Finzi, A; Freire, E; Geng, H; Herschhorn, A; Kwong, PD; Lai, YT; Langley, DR; Louder, MK; Madani, N; Mascola, JR; McDermott, AB; Narpala, S; O'Dell, S; Pancera, M; Rawi, R; Schön, A; Sodroski, J; Soumana, DI | 1 |
| Colonno, RJ; Gong, YF; Ho, HT; Kadow, JF; Langley, DR; Lin, PF; Matiskella, J; Meanwell, NA; Parker, DD; Pearce, BC; Ueda, Y; Wang, T; Yamanaka, GA; Yang, Z; Yin, Z; Zhang, Z; Zheng, M | 1 |
| Cocklin, S; Meuser, ME; Murphy, MB; Rashad, AA | 1 |
| Bailer, RT; Cheung, CSF; Chuang, GY; Doria-Rose, NA; Druz, A; Herschhorn, A; Kwong, PD; Lai, YT; Langley, DR; Lin, B; Louder, MK; Mascola, JR; McKee, K; O'Dell, S; Peng, D; Schön, A; Sodroski, J; Wang, T; Yang, Y; Zhang, B | 1 |
| Arduino, RC; Bauch, T; Chen, M; Graviss, EA; Kimata, JT; Li, M; Liu, W; Wang, J | 1 |
| Alam, SM; Anasti, K; Cronin, K; Desaire, H; Ding, H; Eaton, A; Go, EP; Haynes, BF; Kappes, J; Montefiori, D; Parks, R; Saunders, KO; Sodroski, J | 1 |
3 trial(s) available for triazoles and bms-626529
| Article | Year |
|---|---|
Prediction of virological response and assessment of resistance emergence to the HIV-1 attachment inhibitor BMS-626529 during 8-day monotherapy with its prodrug BMS-663068.
Topics: Anti-HIV Agents; CD4 Lymphocyte Count; CD4-Positive T-Lymphocytes; Disease Susceptibility; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Resistance, Viral; Female; HIV Envelope Protein gp120; HIV Fusion Inhibitors; HIV Infections; HIV-1; Humans; Male; Mutation, Missense; Organophosphates; Piperazines; Prodrugs; RNA, Viral; Treatment Outcome; Triazoles; Viral Load | 2013 |
Pharmacokinetic interactions between BMS-626529, the active moiety of the HIV-1 attachment inhibitor prodrug BMS-663068, and ritonavir or ritonavir-boosted atazanavir in healthy subjects.
Topics: Adolescent; Adult; Anti-HIV Agents; Atazanavir Sulfate; Cross-Over Studies; Drug Interactions; Drug Therapy, Combination; Female; HIV Envelope Protein gp120; HIV Fusion Inhibitors; HIV-1; Humans; Male; Middle Aged; Organophosphates; Piperazines; Ritonavir; Triazoles; Young Adult | 2015 |
Model-Based Phase 3 Dose Selection for HIV-1 Attachment Inhibitor Prodrug BMS-663068 in HIV-1-Infected Patients: Population Pharmacokinetics/Pharmacodynamics of the Active Moiety, BMS-626529.
Topics: Adult; Aged; Aged, 80 and over; Anti-HIV Agents; Drug Administration Schedule; Female; HIV Infections; Humans; Inhibitory Concentration 50; Male; Middle Aged; Organophosphates; Piperazines; Prodrugs; Triazoles | 2016 |
11 other study(ies) available for triazoles and bms-626529
| Article | Year |
|---|---|
Frequency of amino acid changes associated with resistance to attachment inhibitor BMS-626529 in R5- and X4-tropic HIV-1 subtype B.
Topics: Amino Acid Sequence; Amino Acid Substitution; Anti-HIV Agents; CD4 Antigens; Drug Resistance, Viral; HIV Envelope Protein gp120; HIV Infections; HIV-1; Humans; Piperazines; Real-Time Polymerase Chain Reaction; Triazoles; Viral Tropism; Virus Attachment | 2013 |
Activity of the HIV-1 attachment inhibitor BMS-626529, the active component of the prodrug BMS-663068, against CD4-independent viruses and HIV-1 envelopes resistant to other entry inhibitors.
Topics: Anti-HIV Agents; Antibodies, Monoclonal; CCR5 Receptor Antagonists; CD4 Antigens; Cyclohexanes; Drug Resistance, Viral; Enfuvirtide; HEK293 Cells; HIV Envelope Protein gp120; HIV Envelope Protein gp41; HIV-1; Humans; Maraviroc; Organophosphates; Peptide Fragments; Piperazines; Prodrugs; Receptors, CCR5; Receptors, CXCR4; Receptors, Virus; Triazoles; Virus Internalization | 2013 |
Genotypic correlates of susceptibility to HIV-1 attachment inhibitor BMS-626529, the active agent of the prodrug BMS-663068.
Topics: Amino Acid Substitution; Anti-HIV Agents; Drug Resistance, Viral; HIV Envelope Protein gp120; HIV Infections; HIV-1; Humans; Molecular Sequence Data; Organophosphates; Piperazines; Prodrugs; Reverse Genetics; Sequence Analysis, DNA; Triazoles | 2014 |
Genetic barrier for attachment inhibitor BMS-626529 resistance in HIV-1 B and non-B subtypes.
Topics: Amino Acid Substitution; Drug Resistance, Viral; Genotype; HIV Envelope Protein gp120; HIV Fusion Inhibitors; HIV Infections; HIV-1; Humans; Mutation, Missense; Piperazines; Polymorphism, Genetic; Triazoles | 2015 |
Homology models of the HIV-1 attachment inhibitor BMS-626529 bound to gp120 suggest a unique mechanism of action.
Topics: Binding Sites; HIV Envelope Protein gp120; HIV Fusion Inhibitors; Hydrogen Bonding; Molecular Dynamics Simulation; Piperazines; Protein Binding; Structural Homology, Protein; Structure-Activity Relationship; Triazoles | 2015 |
Crystal structures of trimeric HIV envelope with entry inhibitors BMS-378806 and BMS-626529.
Topics: Crystallography, X-Ray; HIV Envelope Protein gp120; HIV Envelope Protein gp41; Models, Molecular; Piperazines; Small Molecule Libraries; Structure-Activity Relationship; Triazoles; Virus Internalization | 2017 |
Discovery of the Human Immunodeficiency Virus Type 1 (HIV-1) Attachment Inhibitor Temsavir and Its Phosphonooxymethyl Prodrug Fostemsavir.
Topics: Animals; Anti-HIV Agents; Caco-2 Cells; Cell Membrane; Drug Discovery; HIV Envelope Protein gp120; HIV-1; Humans; Molecular Docking Simulation; Organophosphates; Permeability; Piperazines; Prodrugs; Protein Conformation; Rats; Triazoles; Virus Attachment | 2018 |
Kinetic Characterization of Novel HIV-1 Entry Inhibitors: Discovery of a Relationship between Off-Rate and Potency.
Topics: Anti-HIV Agents; Cell Line; Cell Survival; Drug Design; env Gene Products, Human Immunodeficiency Virus; HIV Envelope Protein gp120; HIV-1; Humans; Kinetics; Molecular Docking Simulation; Piperazines; Protein Binding; Protein Multimerization; Pyrroles; Structure-Activity Relationship; Surface Plasmon Resonance; Triazoles; Virus Internalization | 2018 |
Lattice engineering enables definition of molecular features allowing for potent small-molecule inhibition of HIV-1 entry.
Topics: Chemical Engineering; Crystallography, X-Ray; Drug Design; HeLa Cells; HIV Envelope Protein gp120; HIV Fusion Inhibitors; HIV-1; Humans; Molecular Docking Simulation; Nanoparticles; Piperazines; Protein Binding; Protein Conformation; Protein Multimerization; Triazoles; Virus Internalization | 2019 |
Clearance of HIV infection by selective elimination of host cells capable of producing HIV.
Topics: Animals; Antigens, CD34; Apoptosis; Autophagy; Azepines; CD4-Positive T-Lymphocytes; HIV Infections; HIV-1; Humans; Mice; Organophosphates; Piperazines; Pyridines; Pyrimidinones; RNA, Viral; T-Lymphocytes; Triazoles | 2020 |
Antigenicity and Immunogenicity of HIV-1 Envelope Trimers Complexed to a Small-Molecule Viral Entry Inhibitor.
Topics: Animals; Anti-HIV Agents; Antibodies, Neutralizing; Antibodies, Viral; CD4 Antigens; CD4-Positive T-Lymphocytes; CHO Cells; Cricetulus; env Gene Products, Human Immunodeficiency Virus; Glycosylation; HEK293 Cells; HIV Infections; HIV-1; Humans; Immunoconjugates; Macaca mulatta; Piperazines; Protein Multimerization; Rabbits; Recombinant Proteins; Triazoles | 2020 |