Page last updated: 2024-08-24

triazoles and betulinic acid

triazoles has been researched along with betulinic acid in 10 studies

Research

Studies (10)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's9 (90.00)24.3611
2020's1 (10.00)2.80

Authors

AuthorsStudies
Cascante, M; Dinis, TC; Marín, S; Moreira, JN; Salvador, JA; Santos, RC1
Barthel, A; Csuk, R; Schwarz, S; Sczepek, R; Siewert, B1
Chinthakindi, PK; Dangroo, NA; Hamid, A; Khan, I; Koul, S; Majeed, R; Sangwan, PL; Saxena, AK; Sharma, PR; Thota, N1
Corsello, MA; Jonnalagadda, SC; Sleet, CE1
Shi, W; Tang, N; Yan, WD1
Chinthakindi, PK; Hamid, A; Hussain, A; Khan, I; Koul, S; Majeed, R; Sangwan, PL; Saxena, AK; Sharma, PR1
Bhushan, S; Chinthakindi, PK; Guru, SK; Khan, I; Koul, S; Rath, SK; Sangwan, PL; Singh, B1
Bhattacharjee, D; Jagadeesh, B; Jain, N; Kavitha, R; Lakshmi, JK; Mallavadhani, UV; Pattnaik, B1
Dzubak, P; Hajduch, M; Pokorny, J; Popa, I; Sidova, V; Urban, M; Zoufaly, P1
Balan-Porcarasu, M; Dehelean, C; Ghiulai, R; Milan, A; Mioc, A; Mioc, M; Nistor, G; Prodea, A; Racoviceanu, R; Semenescu, A; Șoica, C1

Reviews

1 review(s) available for triazoles and betulinic acid

ArticleYear
Betulin-betulinic acid natural product based analogs as anti-cancer agents.
    Anti-cancer agents in medicinal chemistry, 2013, Volume: 13, Issue:10

    Topics: Amines; Antineoplastic Agents, Phytogenic; Betula; Betulinic Acid; Carbamates; Cell Line, Tumor; Cell Survival; Esters; Humans; Imidazoles; Nitriles; Pentacyclic Triterpenes; Plant Bark; Plant Extracts; Triazoles; Triterpenes

2013

Other Studies

9 other study(ies) available for triazoles and betulinic acid

ArticleYear
Synthesis and structure-activity relationship study of novel cytotoxic carbamate and N-acylheterocyclic bearing derivatives of betulin and betulinic acid.
    Bioorganic & medicinal chemistry, 2010, Jun-15, Volume: 18, Issue:12

    Topics: Antineoplastic Agents; Betulinic Acid; Carbamates; Cell Line, Tumor; DNA Topoisomerases, Type I; Drug Screening Assays, Antitumor; Heterocyclic Compounds; Humans; Pentacyclic Triterpenes; Structure-Activity Relationship; Topoisomerase I Inhibitors; Triazoles; Triterpenes

2010
Synthesis, encapsulation and antitumor activity of new betulin derivatives.
    Archiv der Pharmazie, 2011, Volume: 344, Issue:1

    Topics: Antineoplastic Agents; Betulinic Acid; Cell Line, Tumor; Colorimetry; Drug Screening Assays, Antitumor; Fluorescent Dyes; Humans; Liposomes; Neoplasms; Pentacyclic Triterpenes; Pyrazoles; Rhodamines; Structure-Activity Relationship; Triazoles; Triterpenes

2011
Synthesis of 3-O-propargylated betulinic acid and its 1,2,3-triazoles as potential apoptotic agents.
    European journal of medicinal chemistry, 2013, Volume: 63

    Topics: Apoptosis; Betulinic Acid; Cell Line, Tumor; Cell Movement; Cell Survival; DNA Fragmentation; Dose-Response Relationship, Drug; Electrophoresis, Agar Gel; HL-60 Cells; Humans; Inhibitory Concentration 50; MCF-7 Cells; Membrane Potential, Mitochondrial; Models, Chemical; Molecular Structure; Pentacyclic Triterpenes; Structure-Activity Relationship; Triazoles; Triterpenes

2013
Synthesis and cytotoxicity of triterpenoids derived from betulin and betulinic acid via click chemistry.
    Journal of Asian natural products research, 2015, Volume: 17, Issue:2

    Topics: Antineoplastic Agents; Betulinic Acid; Click Chemistry; Drug Screening Assays, Antitumor; HL-60 Cells; Humans; Molecular Structure; Pentacyclic Triterpenes; Structure-Activity Relationship; Triazoles; Triterpenes

2015
PI3K target based novel cyano derivative of betulinic acid induces its signalling inhibition by down-regulation of pGSK3β and cyclin D1 and potentially checks cancer cell proliferation.
    Molecular carcinogenesis, 2016, Volume: 55, Issue:5

    Topics: Betulinic Acid; Cell Line, Tumor; Cell Proliferation; Cyclin D1; Down-Regulation; G1 Phase Cell Cycle Checkpoints; Gene Expression Regulation, Neoplastic; Glycogen Synthase Kinase 3; Glycogen Synthase Kinase 3 beta; HL-60 Cells; Humans; MCF-7 Cells; Neoplasms; Pentacyclic Triterpenes; Phosphoinositide-3 Kinase Inhibitors; Phosphorylation; Signal Transduction; Triazoles; Triterpenes

2016
A novel triazole derivative of betulinic acid induces extrinsic and intrinsic apoptosis in human leukemia HL-60 cells.
    European journal of medicinal chemistry, 2016, Jan-27, Volume: 108

    Topics: Antineoplastic Agents; Apoptosis; Betulinic Acid; Cell Proliferation; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; HL-60 Cells; Humans; Leukemia; Molecular Structure; Pentacyclic Triterpenes; Structure-Activity Relationship; Triazoles; Triterpenes

2016
Synthesis, structural studies, and cytotoxic evaluation of novel ursolic acid hybrids with capabilities to arrest breast cancer cells in mitosis.
    Journal of Asian natural products research, 2017, Volume: 19, Issue:3

    Topics: Betulinic Acid; Cell Cycle; Click Chemistry; Drug Screening Assays, Antitumor; Female; Humans; Mitosis; Molecular Structure; Nuclear Magnetic Resonance, Biomolecular; Pentacyclic Triterpenes; Triazoles; Triterpenes; Ursolic Acid

2017
Cytotoxic conjugates of betulinic acid and substituted triazoles prepared by Huisgen Cycloaddition from 30-azidoderivatives.
    PloS one, 2017, Volume: 12, Issue:2

    Topics: Antineoplastic Agents; Benzaldehydes; Betulinic Acid; Cell Cycle; Cell Line, Tumor; Cell Survival; Cycloaddition Reaction; Humans; Pentacyclic Triterpenes; Triazoles; Triterpenes

2017
The C30-Modulation of Betulinic Acid Using 1,2,4-Triazole: A Promising Strategy for Increasing Its Antimelanoma Cytotoxic Potential.
    Molecules (Basel, Switzerland), 2022, Nov-12, Volume: 27, Issue:22

    Topics: Animals; Antineoplastic Agents; Betulinic Acid; Triazoles; Triterpenes

2022