Page last updated: 2024-08-24

triazoles and bepafant

triazoles has been researched along with bepafant in 158 studies

Research

Studies (158)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's115 (72.78)18.2507
2000's37 (23.42)29.6817
2010's6 (3.80)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Ono, S; Voelkel, NF2
Ambruso, DR; Silliman, CC; Thurman, GW1
Bienvenu, K; Granger, DN; Russell, J1
Ono, S; Voelkel, NF; Westcott, JY1
Faden, AI; Tzendzalian, PA1
Heuer, HO; Muacevic, G1
Levine, BA; McCollum, MO; Olson, MS; Zhou, W2
Chao, W; Levine, BA; Olson, MS; Zhou, W1
Creutzfeldt, W; Fayyazzi, A; Leonhardt, U; Seidensticker, F; Söling, HD; Stöckmann, F1
Krantz, S; Lefer, AM; Ma, XL; Weyrich, AS1
Faden, AI; Halt, P1
Braillon, A; Cailmail, S; Champigneulle, B; Gaudin, C; Kleber, G; Lebrec, D1
Amorim, CZ; Cordeiro, RS; Martins, MA; Vargaftig, BB1
Braquet, C; Köpernik, W; Mest, HJ; Rein, T; Riedel, A1
Brecht, HM; Helmchen, UM; Oberle, G; Schoeppe, W; Stahl, RA; Thaiss, F; Wenzel, U1
Ernst, A; Heuer, HO1
Amorim, CZ; Cordeiro, RS; Henriques, MG; Vargaftig, BB; Weg, VB1
Chao, W; Levine, BA; Olson, MS; Zhou, WG1
Anderson, BO; Banerjee, A; Bensard, DD; Harken, AH; Nelson, DW; Pitman, JM; Poggetti, RS; Shanley, PF; Whitman, GJ1
Borst, HG; Fieguth, HG; Haverich, A; Hirt, SW; Jurmann, M; Wahlers, T1
Gall, DG; MacNaughton, WK1
Bureau, M; Dry, J; Lefort, J; Vargaftig, BB; Vincent, D1
Heuer, HO4
Klee, A; Schmid-Schönbein, GW; Seiffge, D1
Becker, K; Förster, W; Lueddeckens, G; Rappold, R1
Calne, RY; Collier, DG; DaCosta, M; Friend, PJ; Luddington, R; Metcalfe, SM; Pollard, SG; Watson, CJ1
Heuer, HO; Keller, B; Urich, K1
Gundel, RH; Letts, LG; Wegner, CD1
Neugarten, J; Schlondorff, D; Yoo, J1
Conklyn, M; Conyers, G; Cramer, E; Milks, L; Showell, H1
Casals-Stenzel, J; Heuer, HO1
Casals-Stenzel, J; Heuer, HO; Muacevic, G; Weber, KH1
Cordeiro, RS; Fernandes, PD; Henriques, MG; Martins, MA; Silva, PM; Vargaftig, BB; Weg, VB1
Calne, RY; Da Costa, M; Metcalfe, S1
Exner, B; Leonhardt, U; Nebendahl, K; Ritzel, U; Schrock, E; Stöckmann, F1
Bremer, C; Lang, H; Oldhafer, KJ; Pichlmayr, R; Schüttler, W; Spiegel, HU1
Battaglia, E; Bussolino, F; Camussi, G; Emanuelli, G; Lupia, E; Montrucchio, G; Passerini, G1
Chandel, B; Deshpande, Y; Kaminski, DL; Longo, WE; Niehoff, M; Polities, G; Robinson, S; Vernava, AM1
Greenlees, C; Medhurst, AD; Parsons, AA; Smith, SJ1
Biancone, L; Camussi, G; Duc, TM; Montrucchio, G; Ruikun, C; Silvestro, L; Sommer, F1
Abdo, EE; Bonizzia, A; Coelho, AM; Jancar, S; Kwasniewski, FH; Machado, MC; Sampietre, SN1
Aglietta, M; Arese, M; Barra, L; Benelli, R; Bussolino, F; Ghigo, D; Montrucchio, G; Primo, L; Rola-Pleszczynski, MR; Sanavio, F1
Qin, X; Yu, P; Yuan, J1
Appleyard, CB; Hillier, K1
Cooper, K; Fray, MJ; Parry, MJ; Richardson, K; Steele, J1
Hirafuji, M; Shinoda, H1
Chandel, B; Deshpande, Y; Kaminski, DL; Kulkarni, A; Longo, WE; Niehoff, M; Polities, G; Vernava, AM1
Das, A; Larkin, SW; Nourshargh, S; Williams, TJ1
Brecht, HM; Haberstroh, U; Mihatsch, MJ; Oberle, G; Stahl, RA; Thaiss, F1
Carter, JD; Chandel, B; Deshpande, Y; Kaminski, DL; Kulkarni, AD; Longo, WE; Niehoff, M; Polites, G; Standeven, J; Vernava, AM1
Berthiaume, N; Bkaily, G; Claing, A; D'Orléans-Juste, P; Rola-Pleszczynski, M; Sirois, P1
Ambruso, DR; Clay, KL; Johnson, CA; Silliman, CC; Thurman, GW2
Cury, Y; Jancar, S; Oga, S; Teixeira, CF1
Ashino, Y; Fujimura, S; Hoshikawa, Y; Nishimura, T; Noda, M; Ono, S; Tabata, S; Tanita, T; Ueda, S1
Andrews, MJ; Cunningham, FM; Foster, AP; Lees, P1
Alloatti, G; Camussi, G; Montrucchio, G1
Calne, R; Chávez-Cartaya, RE; Jamieson, NV; Metcalfe, S; Ramirez-Romero, P1
Calne, RY; Luddington, R; Metcalfe, SM; St John Collier, DG; Watson, CJ1
Häyry, P; Mennander, A; Paavonen, T; Räisänen, A; Ustinov, J1
De Brum-Fernandes, AJ; Fraga, CA; Jancar, S; Rocha, FA; Timo-Iaria, C1
Abdulnour, E; Bkaily, G; d'Orléans-Juste, P; Naik, R; Pérodin, J; Rola-Pleszczynski, M; Stankova, J1
Choy, PC; Hu, W; Man, RY; McNicholl, IK1
Parent, JL; Stankova, J1
Jung, TT; Miller, S; Rhee, CK; Weeks, D1
Alloatti, G; Camussi, G; Emanuelli, G; Lucchina, PG; Lupia, E; Mariano, F; Montrucchio, G; Musso, E1
Becker, K; Förster, W; Grupe, R; Lueddeckens, G1
Alloatti, G; Cacace, G; Camussi, G; Comino, A; De Filippi, PG; Emanuelli, G; Mariano, F; Montrucchio, G; Polloni, R1
Levine, BA; Olson, MS; Zhou, W1
Buxton, DB; Halvorsen, O; Olson, MS; Zhou, W1
Amorim, CZ; Cordeiro, RS; Vargaftig, BB1
Cunningham, FM; Foster, AP; Lees, P1
Fu, W; Xiao, G; Yu, P2
Knight, KR; Lepore, DA; Morrison, WA; Riccio, M; Stewart, AG1
Ambruso, DR; Clay, KL; Dickey, WO; Johnson, CA; Paterson, AJ; Silliman, CC; Thurman, GW1
Lekka, M; Obladen, M; Scheid, A; Segerer, H; Wagner, MH1
Frostegård, J; Huang, YH; Lorentzen, JC; Owman, H; Rönnelid, J; Schäfer-Elinder, L1
Cacace, G; Camussi, G; De Filippi, PG; De Martino, A; Emanuelli, G; Lupia, E; Montrucchio, G; Savu, SR; Silvestro, L1
Ferreira, MG; Fonteles, MC1
Bussolino, F; Camussi, G; Comoglio, PM; Lupia, E; Montrucchio, G; Soldi, R1
Kozel, TR; Lupan, DM; Manalo, PB; Roberts, JS; Savoy, AC; Schlageter, AM; Weinhold, LC1
Adler, L; Caplan, MS; Hedlund, E; Hsueh, W; Lickerman, M1
Andersson-Engels, S; Liu, DL; Svanberg, K; Svanberg, S; Wang, I1
Frostegård, J; Huang, YH; Rönnelid, J; Schäfer-Elinder, L1
Ammit, AJ; O'Neill, C1
Arese, M; Battaglia, E; Bussolino, F; Camussi, G; de Martino, A; Lupia, E; Montrucchio, G; Tizzani, A1
De Matos, IM; Freire-Maia, L; Leite, R; Rocha, OA1
Freudenberg, J; Jocks, T; Stahl, RA; Zahner, G1
Borman, RA; Hillier, K; Jewell, R1
Allard, JD; Ambruso, DR; Elzi, DJ; Johnson, JL; Silliman, CC; Tuder, RM; Voelkel, NF1
Bac, P; Dupont, C; Evrard, P; Gressens, P; Maurois, P; Pages, N; Stables, JP; Vamecq, J1
Baumann, G; Braun, M; Felix, SB; Hunger, T; Pietsch, P; Roediger, A1
Hibler, S; Ibe, BO; Raj, JU1
Jancar, S; Russo, M; Starobinas, N; Steil, AA; Tavares de Lima, W; Teixeira, CF1
Jancar, S; Steil, AA; Tavares de Lima, W1
Diefenbeck, M; Hammer, C; Linke, R; Seehofer, D1
Biancone, L; Bussolati, B; Cambi, V; Camussi, G; David, S; Foà, R; Mariano, F1
Baethmann, A; Pickelmann, S; Schürer, L; Uhl, E1
Baethmann, A; Pickelmann, S; Röhrich, F; Schürer, L; Uhl, E1
Battaglia, E; Brizzi, MF; Camussi, G; Del Sorbo, L; Dentelli, P; Garbarino, G; Montrucchio, G; Pegoraro, L1
Chung, PS; Jeong, PS; Jung, TT; Kim, YH; Rhee, CK1
Biancone, L; Bussolati, B; Camussi, G; Conaldi, PG; Del Sorbo, L; DeMartino, A; Toniolo, A1
Bocheński, J; Chłopicki, S; Gryglewski, RJ1
Alloatti, G; Camussi, G; De Martino, A; Montrucchio, G; Penna, C1
Brizzi, MF; Camussi, G; Del Sorbo, L; Dentelli, P; Garbarino, G; Molinar, A; Pegoraro, L; Rosso, A1
Freire-Maia, L; Matos, IM; Seabra, DG; Souza, DG; Teixeira, MM1
Flickinger, BD; Mustafa, SB; Olson, MS1
Albini, A; Biancone, L; Boccellino, M; Bussolati, B; Camussi, G; Cantaluppi, V; Conaldi, PG; Del Sorbo, L; Toniolo, A1
Chłopicki, S; Olszanecki, R1
Battaglia, E; Biancone, L; Boccellino, M; Camussi, G; Del Sorbo, L; Emanuelli, G; Lupia, E; Montrucchio, G1
Chang, H; De Plaen, IG; Hsueh, W; Remick, DG; Tan, XD; Wang, L1
Domont, GB; Frutuoso, VS; Martins, MA; Moussatché, H; Perales, J; Rocha, SL1
Caplan, M; Chang, H; Gonzalez-Crussi, F; Hsueh, W; Qu, XW; Tan, XD1
Howard, KM; Olson, MS1
Ahmed, A; Ahmed, Z; Dearn, S; Eggo, MC; Lewis, A; Rahman, M1
Aktan, B; Gundogdu, C; Karasen, RM; Ozdemir, H; Sutbeyaz, Y1
Palmer, C; Roberts, RL; Viswanath, M1
Barreiro, EJ; de Miranda, AL; Fraga, AG; Fraga, CA; Rodrigues, CR1
Biancone, L; Bussolati, B; Camussi, G; Cassoni, P; Montrucchio, G; Rola-Pleszczynski, M; Russo, S1
Alloatti, G; Camussi, G; Mariano, F; Penna, C1
Andrade, SP; Cara, DC; Cassali, GD; Coutinho, SF; Poole, SP; Silveira, MR; Souza, DG; Teixeira, MM1
Arese, M; Biancone, L; Bussolino, F; Camussi, G; Del Sorbo, L; Giraudo, E; Tizzani, M1
Bianchi, L; Cellai, C; Della Malva, N; Laurenzana, A; Paoletti, F; Vannucchi, AM1
Carlson, SL; Hostettler, ME1
Carlson, SL; Hostettler, ME; Knapp, PE1
Biffl, WL; Carnaggio, R; Gonzalez, RJ; Moore, EE; Offner, PJ; Silliman, CC; West, KE1
Garfield, RE; Marx, SG; Maul, H; Saade, GR; Shi, L1
Bussolati, B; Camussi, G; Deambrosis, I; Mariano, F; Russo, S1
Alloatti, G; Altruda, F; Azzolino, O; Barberis, L; Bedendi, I; Bosco, O; Del Sorbo, L; Hirsch, E; Levi, R; Malan, D; Marcantoni, A; Montrucchio, G; Penna, C; Wymann, M1
Rhee, CK1
Jung, TT; Park, SK; Rhee, CK1
Al-Salti, W; Booth, IW; Coney, AM; Ewer, AK; Marshall, JM; Ramani, P1
John, EO; Jung, TT; Park, SK; Park, YS; Rhee, CK1
Chlopicki, S; Jakubowski, A; Olszanecki, R1
Akcay, F; Gundogdu, C; Karasen, RM; Taysi, S; Uslu, C1
Alloatti, G; Berta, G; Cappello, S; Gattullo, D; Losano, G; Mognetti, B; Pagliaro, P; Penna, C1
Cellai, C; Laurenzana, A; Pancrazzi, A; Paoletti, F; Romanelli, MN; Vannucchi, AM1
Chłopicki, S; Jawień, J; Korbut, R; Lomnicka, M1
De Plaen, IG; Ghosh, S; Han, XB; Hsueh, W; Liu, X; May, MJ1
Amarante Mendes, JG; de Oliveira, SI; Fernandes, PD; Jancar, S1
Calixto, JB; Kassuya, CA; Marotta, DM; Menezes-de-Lima, O; Rehder, VL; Silvestre, A1
Bertani, A; Bertani, C; Campodonico, A; Carboni, A; Marchesini, A; Mazzanti, L; Pangrazi, PP; Riccio, M; Scalise, A; Talevi, D1
Jancar, S; Machado, MC; Molan, NA; Shio, MT; Souza, LJ1
Abdallah, MF; Ibe, BO; Portugal, AM; Raj, JU1
Chen, C; Chen, H; Li, XH; Xia, SH1
Balliu, M; Bianchi, E; Bosi, A; Caporale, R; Cellai, C; Cocco, PL; Ferrari, S; Laurenzana, A; Manfredini, R; Mannelli, F; Miniati, D; Paoletti, F; Sdelci, S; Stankova, J; Vannucchi, AM; Veronneau, S1
Andrade, LN; Chammas, R; de Oliveira, SI; Fernandes, PD; Jancar, S; Nonogaki, S; Onuchic, AC; Pinheiro, MC; Rohde, CB1
Abdel-Al, M; Ditmyer, M; Howard, KM; Patel, N1
Arteaga, A; Bae, R; Ibe, BO; Raj, JU1
Demopoulos, CA; Papakyriakou, A; Philippopoulos, AI; Tsoupras, AB1
Aguiar, CF; Andrade-Oliveira, V; Braga, TT; Câmara, NO; Castoldi, A; Correa-Costa, M; Hiyane, MI; Jancar, S; Malheiros, DM; Origassa, CS; Rios, FJ; Rodas, AC1
Bizzarro, B; Jancar, S; Koga, MM; Rios, FJ; Sá-Nunes, A1

Reviews

3 review(s) available for triazoles and bepafant

ArticleYear
The effects of hetrazepine PAF antagonists in preclinical models of asthma.
    Agents and actions. Supplements, 1991, Volume: 34

    Topics: Anaphylaxis; Animals; Antigens; Asthma; Azepines; Blood Platelets; Bronchi; Bronchoconstriction; Capillary Permeability; Cell Movement; Eosinophils; Lung; Platelet Activating Factor; Respiratory Hypersensitivity; Triazoles

1991
Involvement of platelet-activating factor (PAF) in septic shock and priming as indicated by the effect of hetrazepinoic PAF antagonists.
    Lipids, 1991, Volume: 26, Issue:12

    Topics: Animals; Azepines; Endotoxins; Humans; Models, Biological; Multiple Organ Failure; Platelet Activating Factor; Shock, Septic; Triazoles

1991
Therapy for acute pancreatitis with platelet-activating factor receptor antagonists.
    World journal of gastroenterology, 2008, Aug-14, Volume: 14, Issue:30

    Topics: Acute Disease; Animals; Anti-Inflammatory Agents; Azepines; Ginkgolides; Humans; Imidazoles; Lactones; Leucine; Pancreatitis; Platelet Aggregation Inhibitors; Platelet Membrane Glycoproteins; Pyridinium Compounds; Receptors, G-Protein-Coupled; Tetrahydroisoquinolines; Treatment Outcome; Triazoles

2008

Other Studies

155 other study(ies) available for triazoles and bepafant

ArticleYear
PAF receptor blockade inhibits lung vascular changes in the rat monocrotaline model.
    Lung, 1992, Volume: 170, Issue:1

    Topics: Animals; Azepines; Blood Pressure; Hydroxyproline; Hypertension, Pulmonary; Lung; Male; Monocrotaline; Platelet Activating Factor; Platelet Membrane Glycoproteins; Pulmonary Artery; Rats; Rats, Inbred Strains; Receptors, Cell Surface; Receptors, G-Protein-Coupled; Thymidine; Triazoles

1992
Stored blood components contain agents that prime the neutrophil NADPH oxidase through the platelet-activating-factor receptor.
    Vox sanguinis, 1992, Volume: 63, Issue:2

    Topics: Azepines; Blood Platelets; Enzyme Activation; Erythrocytes; Humans; NADH, NADPH Oxidoreductases; NADPH Oxidases; Neutrophils; Platelet Activating Factor; Platelet Membrane Glycoproteins; Receptors, Cell Surface; Receptors, G-Protein-Coupled; Triazoles

1992
Leukotriene B4 mediates shear rate-dependent leukocyte adhesion in mesenteric venules.
    Circulation research, 1992, Volume: 71, Issue:4

    Topics: Animals; Antigens, CD; Azepines; Benzopyrans; Cats; CD18 Antigens; Endothelium, Vascular; Indoles; Leukocytes; Leukotriene B4; Mesenteric Veins; Platelet Activating Factor; Receptors, Leukocyte-Adhesion; Triazoles; Venules

1992
PAF antagonists inhibit pulmonary vascular remodeling induced by hypobaric hypoxia in rats.
    Journal of applied physiology (Bethesda, Md. : 1985), 1992, Volume: 73, Issue:3

    Topics: Animals; Azepines; Endothelins; Hypertension, Pulmonary; Hypoxia; In Vitro Techniques; Lung; Male; N-Formylmethionine Leucyl-Phenylalanine; Platelet Activating Factor; Pulmonary Circulation; Rats; Triazoles; Vasoconstriction

1992
Platelet-activating factor antagonists limit glycine changes and behavioral deficits after brain trauma.
    The American journal of physiology, 1992, Volume: 263, Issue:4 Pt 2

    Topics: Animals; Azepines; Behavior, Animal; Body Water; Brain; Brain Injuries; Cations; Dialysis; Diterpenes; Ginkgolides; Glycine; Lactones; Male; Platelet Activating Factor; Rats; Rats, Sprague-Dawley; Triazoles

1992
Platelet-activating factor antagonists in experimental shock.
    Arzneimittel-Forschung, 1992, Volume: 42, Issue:8

    Topics: Acid-Base Equilibrium; Animals; Azepines; Blood Pressure; Electrocardiography; Endotoxins; Hyperkalemia; Male; Platelet Activating Factor; Rats; Rats, Sprague-Dawley; Shock; Triazoles

1992
Inflammation and platelet-activating factor production during hepatic ischemia/reperfusion.
    Hepatology (Baltimore, Md.), 1992, Volume: 16, Issue:5

    Topics: Alanine Transaminase; Allopurinol; Animals; Azepines; Gadolinium; Hepatitis; Ischemia; Leukocytes; Liver; Male; Necrosis; Platelet Activating Factor; Rats; Rats, Sprague-Dawley; Reperfusion Injury; Triazoles

1992
Role of platelet-activating factor in hepatic responses after bile duct ligation in rats.
    The American journal of physiology, 1992, Volume: 263, Issue:5 Pt 1

    Topics: Animals; Azepines; Bile Ducts; Cholestasis; Diterpenes; Endotoxins; Ginkgolides; Kupffer Cells; Lactones; Ligation; Lipopolysaccharides; Liver; Male; Platelet Activating Factor; Rats; Rats, Sprague-Dawley; Triazoles

1992
Influence of a platelet-activating factor antagonist on severe pancreatitis in two experimental models.
    International journal of pancreatology : official journal of the International Association of Pancreatology, 1992, Volume: 12, Issue:2

    Topics: Animals; Ascites; Azepines; Male; Pancreatitis; Platelet Activating Factor; Rats; Rats, Wistar; Survival Rate; Triazoles

1992
Mechanisms of the cardioprotective actions of WEB-2170, bepafant, a platelet activating factor antagonist, in myocardial ischemia and reperfusion.
    The Journal of pharmacology and experimental therapeutics, 1992, Volume: 260, Issue:3

    Topics: Animals; Azepines; Cats; Cell Adhesion; Coronary Disease; Creatine Kinase; Endothelium, Vascular; Heart; Hemodynamics; Male; Myocardial Reperfusion Injury; Neutrophils; Platelet Activating Factor; Platelet Aggregation; Triazoles

1992
Role of platelet-activating factor in pancreatitis-associated acute lung injury in the rat.
    The American journal of pathology, 1992, Volume: 140, Issue:4

    Topics: Animals; Azepines; Bronchoalveolar Lavage Fluid; Diterpenes; Eicosanoids; Enzymes; Ginkgolides; Lactones; Lung; Pancreatitis; Platelet Activating Factor; Rats; Triazoles

1992
Platelet-activating factor reduces spinal cord blood flow and causes behavioral deficits after intrathecal administration in rats through a specific receptor mechanism.
    The Journal of pharmacology and experimental therapeutics, 1992, Volume: 261, Issue:3

    Topics: Animals; Azepines; Blood Pressure; Dose-Response Relationship, Drug; Injections, Spinal; Male; Motor Activity; Platelet Activating Factor; Rats; Rats, Inbred Strains; Spinal Cord; Triazoles

1992
Hemodynamic effects of endotoxin and platelet activating factor in cirrhotic rats.
    Gastroenterology, 1992, Volume: 103, Issue:1

    Topics: Animals; Azepines; Blood Pressure; Diterpenes; Endotoxins; Ginkgolides; Heart Rate; Hemodynamics; Lactones; Liver Cirrhosis, Experimental; Male; Platelet Activating Factor; Portal System; Rats; Rats, Inbred Strains; Triazoles

1992
Differential inhibition by the PAF receptor antagonist, WEB 2170, of allergic inflammation in single sensitized and boosted mice.
    European journal of pharmacology, 1992, Jan-28, Volume: 211, Issue:1

    Topics: Animals; Antigens; Azepines; Dose-Response Relationship, Drug; Edema; Injections, Intraperitoneal; Male; Mice; Mice, Inbred Strains; Platelet Activating Factor; Triazoles

1992
Effect of BN 52256 and other mediator antagonists on ouabain-induced ventricular fibrillation in sensitized guinea-pigs and on ischemia-induced fibrillation in rats.
    Agents and actions. Supplements, 1992, Volume: 37

    Topics: Anesthesia; Animals; Anti-Arrhythmia Agents; Azepines; Clemastine; Coronary Disease; Coronary Vessels; Guinea Pigs; Organoselenium Compounds; Ouabain; Piperidines; Platelet Activating Factor; Propranolol; Rats; Triazoles; Umbelliferones; Ventricular Fibrillation

1992
The platelet activating factor receptor antagonist WEB 2170 improves glomerular hemodynamics and morphology in a proliferative model of mesangial cell injury.
    Journal of the American Society of Nephrology : JASN, 1991, Volume: 2, Issue:1

    Topics: Animals; Antilymphocyte Serum; Azepines; Dinoprostone; Disease Models, Animal; Glomerular Filtration Rate; Glomerular Mesangium; Glomerulonephritis; Inulin; Male; Platelet Membrane Glycoproteins; Rats; Rats, Inbred Strains; Receptors, Cell Surface; Receptors, G-Protein-Coupled; Thromboxane B2; Triazoles

1991
PAF receptor antagonists influence asphyxia-induced changes of the inner ear.
    Journal of lipid mediators, 1991, Volume: 4, Issue:3

    Topics: Animals; Asphyxia; Azepines; Cochlea; Electrophysiology; Female; Guinea Pigs; Kinetics; Male; Platelet Membrane Glycoproteins; Receptors, Cell Surface; Receptors, G-Protein-Coupled; Triazoles

1991
Effect of PAF-acether antagonists on active anaphylactic mouse paw edema.
    Lipids, 1991, Volume: 26, Issue:12

    Topics: 4,5-Dihydro-1-(3-(trifluoromethyl)phenyl)-1H-pyrazol-3-amine; Acetophenones; Anaphylaxis; Animals; Aspirin; Azepines; Cimetidine; Dexamethasone; Edema; Male; Meclizine; Methysergide; Mice; Ovalbumin; Platelet Activating Factor; Platelet Membrane Glycoproteins; Prednisolone; Receptors, Cell Surface; Receptors, G-Protein-Coupled; Tetrazoles; Triazoles

1991
Evidence for platelet-activating factor as a late-phase mediator of chronic pancreatitis in the rat.
    The American journal of pathology, 1990, Volume: 137, Issue:6

    Topics: Amylases; Animals; Azepines; Chronic Disease; Diterpenes; Ginkgolides; Lactones; Ligation; Male; Pancreas; Pancreatic Ducts; Pancreatitis; Platelet Activating Factor; Rats; Rats, Inbred Strains; Time Factors; Triazoles

1990
Primed neutrophils injure rat lung through a platelet-activating factor-dependent mechanism.
    The Journal of surgical research, 1991, Volume: 50, Issue:5

    Topics: Animals; Azepines; Lipopolysaccharides; Lung; Lung Diseases; Male; Neutrophils; Nitroblue Tetrazolium; Oligopeptides; Peroxidase; Platelet Activating Factor; Rats; Rats, Inbred Strains; Serum Albumin; Staining and Labeling; Triazoles

1991
Future horizons of lung preservation by application of a platelet-activating factor antagonist compared with current clinical standards. Euro-Collins flush perfusion versus donor core cooling.
    The Journal of thoracic and cardiovascular surgery, 1992, Volume: 103, Issue:2

    Topics: Animals; Azepines; Cold Temperature; Dogs; Epoprostenol; Heart-Lung Transplantation; Hemodynamics; Hypertonic Solutions; Organ Preservation; Oxygen; Platelet Activating Factor; Pulmonary Circulation; Triazoles

1992
Mechanisms of platelet-activating factor-induced electrolyte transport in the rat jejunum.
    European journal of pharmacology, 1991, Jul-23, Volume: 200, Issue:1

    Topics: Animals; Arachidonic Acids; Azepines; Biological Transport, Active; Chlorides; Dinoprostone; Eicosanoic Acids; Electrophysiology; Female; Indomethacin; Jejunum; Platelet Activating Factor; Quinacrine; Rats; Triazoles

1991
Dissociation between LPS-induced bronchial hyperreactivity and airway edema in the guinea-pig.
    Agents and actions, 1991, Volume: 34, Issue:1-2

    Topics: Animals; Aspirin; Azepines; Bronchial Diseases; Bronchoalveolar Lavage Fluid; Escherichia coli; Guinea Pigs; Lipopolysaccharides; Macrophages; Male; Neutrophils; Platelet Activating Factor; Pulmonary Edema; Pyrilamine; Respiratory Hypersensitivity; Triazoles

1991
Effects of platelet activating factor on rat platelets in vivo.
    European journal of pharmacology, 1991, Dec-17, Volume: 209, Issue:3

    Topics: Adenosine Diphosphate; Animals; Azepines; Blood Platelets; In Vitro Techniques; Leukocytes; Male; Platelet Activating Factor; Platelet Activation; Platelet Aggregation; Platelet Count; Pulmonary Embolism; Rats; Rats, Inbred Strains; Triazoles

1991
Influence of aminophylline and ketotifen in comparison to the lipoxygenase inhibitors NDGA and esculetin and the PAF antagonists WEB 2170 [correction of 2107] and BN 52021 on endothelin-1 induced vaso- and bronchoconstriction.
    Prostaglandins, leukotrienes, and essential fatty acids, 1991, Volume: 44, Issue:3

    Topics: Aminophylline; Animals; Azepines; Bronchoalveolar Lavage Fluid; Bronchoconstriction; Bronchoconstrictor Agents; Diterpenes; Endothelins; Ginkgolides; Guinea Pigs; Ketotifen; Lactones; Lipoxygenase Inhibitors; Lung; Male; Masoprocol; Platelet Activating Factor; Platelet Aggregation Inhibitors; Theophylline; Thromboxane B2; Triazoles; Umbelliferones; Vasoconstriction; Vasoconstrictor Agents

1991
Effect of the hetrazepinoic platelet-activating factor antagonist Bepafant (WEB 2170) in models of active and passive anaphylaxis in mice and guinea pigs.
    Lipids, 1991, Volume: 26, Issue:12

    Topics: Anaphylaxis; Animals; Azepines; Blood Pressure; Guinea Pigs; Lung; Male; Mice; Mice, Inbred Strains; Ovalbumin; Passive Cutaneous Anaphylaxis; Platelet Activating Factor; Propranolol; Pyrilamine; Respiration; Triazoles

1991
PAF antagonists inhibit monocrotaline-induced lung injury and pulmonary hypertension.
    Journal of applied physiology (Bethesda, Md. : 1985), 1991, Volume: 71, Issue:6

    Topics: Animals; Azepines; Cardiomegaly; Hypertension, Pulmonary; Lung; Lung Injury; Male; Monocrotaline; Platelet Activating Factor; Rats; Rats, Inbred Strains; Triazoles

1991
Survival of renal allografted dogs after limited therapy with cyclosporine and the PAF antagonist WEB 2170.
    Transplantation proceedings, 1991, Volume: 23, Issue:4

    Topics: Animals; Azepines; Cyclosporins; Dogs; Dose-Response Relationship, Drug; Drug Therapy, Combination; Graft Survival; Immunosuppressive Agents; Kidney Transplantation; Platelet Activating Factor; Triazoles

1991
Action of the racemate and the isomers of the platelet-activating factor antagonist bepafant (WEB 2170) after oral administration to guinea-pigs and rats.
    Naunyn-Schmiedeberg's archives of pharmacology, 1991, Volume: 343, Issue:5

    Topics: Administration, Oral; Animals; Azepines; Blood Pressure; Dose-Response Relationship, Drug; Guinea Pigs; Male; Platelet Activating Factor; Pulmonary Ventilation; Rats; Rats, Inbred Strains; Stereoisomerism; Structure-Activity Relationship; Time Factors; Triazoles

1991
The role of platelet activating factor in airway inflammation, airway hyperresponsiveness, and pulmonary function in monkeys.
    Annals of the New York Academy of Sciences, 1991, Volume: 629

    Topics: Aerosols; Animals; Antigens; Azepines; Bronchoconstriction; Lung; Macaca fascicularis; Male; Methacholine Chloride; Neutrophils; Platelet Activating Factor; Respiratory Physiological Phenomena; Respiratory System; Triazoles

1991
Inhibition of active anaphylaxis in mice and guinea pigs by the new hetrazepinoic PAF antagonist bepafant (WEB 2170).
    European journal of pharmacology, 1991, Jun-25, Volume: 199, Issue:2

    Topics: Anaphylaxis; Animals; Azepines; Blood Pressure; Bronchoconstriction; Guinea Pigs; Immunization; Male; Mice; Ovalbumin; Platelet Activating Factor; Propranolol; Pulmonary Ventilation; Pyrilamine; Triazoles

1991
Protective effects of specific platelet-activating factor receptor antagonists in experimental glomerulonephritis.
    The Journal of pharmacology and experimental therapeutics, 1991, Volume: 256, Issue:3

    Topics: Animals; Azepines; Glomerular Filtration Rate; Glomerulonephritis; Hemodynamics; Kidney; Male; Platelet Activating Factor; Rats; Rats, Inbred Strains; Triazoles

1991
A factor in serum lowers resistance and opens tight junctions of MDCK cells.
    The American journal of physiology, 1990, Volume: 259, Issue:4 Pt 1

    Topics: Animals; Azepines; Blood; Cell Line; Chromatography, Gel; Complement C3a; Complement C5a; Culture Media; Dogs; Humans; Inflammation; Intercellular Junctions; Kidney; Kinetics; Molecular Weight; Platelet Activating Factor; Serum Albumin; Triazoles

1990
Use of WEB 2086 and WEB 2170 as platelet-activating factor antagonists.
    Methods in enzymology, 1990, Volume: 187

    Topics: Animals; Azepines; Blood Platelets; Humans; In Vitro Techniques; Lung; Methods; Molecular Structure; Neutrophils; Platelet Activating Factor; Platelet Aggregation; Rabbits; Triazoles

1990
Pharmacologic activity of bepafant (WEB 2170), a new and selective hetrazepinoic antagonist of platelet activating factor.
    The Journal of pharmacology and experimental therapeutics, 1990, Volume: 255, Issue:3

    Topics: Administration, Oral; Animals; Azepines; Bronchoconstriction; Capillary Permeability; Cell Aggregation; Dose-Response Relationship, Drug; Guinea Pigs; Humans; Hypotension; Infusions, Intravenous; Injections, Intradermal; Injections, Intravenous; Male; Mice; Mice, Inbred Strains; Neutrophils; Platelet Activating Factor; Platelet Aggregation; Platelet Aggregation Inhibitors; Rats; Rats, Inbred Strains; Skin; Time Factors; Triazoles

1990
Differential inhibition by two hetrazepine PAF antagonists of acute inflammation in the mouse.
    British journal of pharmacology, 1990, Volume: 99, Issue:1

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Azepines; Carrageenan; Dose-Response Relationship, Drug; Edema; Exudates and Transudates; Female; Leukocyte Count; Male; Mice; Platelet Activating Factor; Pleurisy; Serotonin; Triazines; Triazoles

1990
Prolongation of rat heart allograft survival using low-dose cyclosporine and PAF antagonist WEB 2170.
    Transplantation proceedings, 1990, Volume: 22, Issue:4

    Topics: Animals; Azepines; Cyclosporins; Graft Rejection; Graft Survival; Heart Transplantation; Platelet Activating Factor; Rats; Transplantation, Heterotopic; Transplantation, Homologous; Triazoles

1990
Effect of a platelet-activating factor antagonist on pancreas perfusion after 24 h of ischemia.
    Pancreas, 1995, Volume: 11, Issue:2

    Topics: Animals; Azepines; Cold Temperature; Ischemia; Pancreas; Platelet Activating Factor; Reperfusion; Swine; Tissue Preservation; Triazoles

1995
Beneficial effect of the platelet-activating factor antagonist WEB 2170 on reperfusion injury after orthotopic liver transplantation.
    Transplantation proceedings, 1995, Volume: 27, Issue:5

    Topics: Alanine Transaminase; Animals; Aspartate Aminotransferases; Azepines; Bilirubin; Body Weight; Graft Survival; Liver; Liver Function Tests; Liver Transplantation; Platelet Activating Factor; Platelet Aggregation Inhibitors; Reperfusion Injury; Swine; Time Factors; Triazoles

1995
Tumor necrosis factor alpha-induced angiogenesis depends on in situ platelet-activating factor biosynthesis.
    The Journal of experimental medicine, 1994, Jul-01, Volume: 180, Issue:1

    Topics: Animals; Azepines; Collagen; Drug Combinations; Female; Laminin; Mice; Mice, Inbred C57BL; Neovascularization, Pathologic; Platelet Activating Factor; Proteoglycans; Triazoles; Tumor Necrosis Factor-alpha

1994
Effect of platelet-activating factor and its antagonists on colonic dysmotility and tissue levels of colonic neuropeptides.
    European journal of pharmacology, 1994, Apr-11, Volume: 256, Issue:1

    Topics: Alprazolam; Animals; Azepines; Colitis; Colon; Gastrointestinal Motility; In Vitro Techniques; Iodine Radioisotopes; Neuropeptides; Platelet Activating Factor; Rabbits; Substance P; Triazoles; Vasoactive Intestinal Peptide

1994
Nitric oxide synthase inhibitors 7- and 6-nitroindazole relax smooth muscle in vitro.
    European journal of pharmacology, 1994, Apr-11, Volume: 256, Issue:1

    Topics: Alprazolam; Animals; Azepines; Colitis; Colon; Gastrointestinal Motility; In Vitro Techniques; Iodine Radioisotopes; Neuropeptides; Platelet Activating Factor; Rabbits; Substance P; Triazoles; Vasoactive Intestinal Peptide

1994
Platelet-activating factor-induced endothelial cell expression of adhesion molecules and modulation of surface glycocalyx, evaluated by electron spectroscopy chemical analysis.
    Seminars in thrombosis and hemostasis, 1994, Volume: 20, Issue:2

    Topics: Antibodies, Monoclonal; Azepines; CD18 Antigens; Cell Adhesion; Cell Adhesion Molecules; Cells, Cultured; Cycloheximide; Electron Probe Microanalysis; Endothelium, Vascular; Fluorescent Antibody Technique; Gene Expression Regulation; Glycoproteins; Humans; Neutrophils; P-Selectin; Platelet Activating Factor; Platelet Membrane Glycoproteins; Polysaccharides; Proteoglycans; Triazoles; Umbilical Veins

1994
Effect of PAF antagonists on cerulein-induced pancreatitis.
    Journal of lipid mediators and cell signalling, 1995, Volume: 11, Issue:1

    Topics: Acute Disease; Amylases; Animals; Azepines; Capillary Permeability; Ceruletide; Diterpenes; Evans Blue; Ginkgolides; Lactones; Male; Pancreas; Pancreatitis; Platelet Activating Factor; Rats; Rats, Wistar; Triazoles

1995
Platelet activating factor produced in vitro by Kaposi's sarcoma cells induces and sustains in vivo angiogenesis.
    The Journal of clinical investigation, 1995, Volume: 96, Issue:2

    Topics: Aged; Animals; Azepines; Base Sequence; Cell Line; Chemotaxis; Choriocarcinoma; Collagen; Culture Media, Conditioned; Cytokines; Dogs; Drug Combinations; Endothelium, Vascular; Female; Growth Substances; Humans; Interleukin-1; Laminin; Lymphoma, Large B-Cell, Diffuse; Macrophages; Male; Mice; Mice, Inbred DBA; Molecular Sequence Data; Neoplasm Proteins; Neovascularization, Pathologic; Platelet Activating Factor; Platelet Membrane Glycoproteins; Proteoglycans; Receptors, Cell Surface; Receptors, G-Protein-Coupled; Sarcoma, Kaposi; Skin Neoplasms; Thrombin; Triazoles; Tumor Cells, Cultured; Tumor Necrosis Factor-alpha; Umbilical Veins; Uterine Neoplasms

1995
[The effect of platelet-activating factor antagonists on early bacteria translocation of rat after burn injury].
    Zhonghua wai ke za zhi [Chinese journal of surgery], 1995, Volume: 33, Issue:4

    Topics: Animals; Azepines; Bacterial Translocation; Burns; Escherichia coli; Escherichia coli Infections; Platelet Activating Factor; Random Allocation; Rats; Rats, Wistar; Triazoles

1995
Biosynthesis of platelet-activating factor in normal and inflamed human colon mucosa: evidence for the involvement of the pathway of platelet-activating factor synthesis de novo in inflammatory bowel disease.
    Clinical science (London, England : 1979), 1995, Volume: 88, Issue:6

    Topics: Aged; Azepines; Chromatography, High Pressure Liquid; Chromatography, Thin Layer; Colon; Culture Techniques; Cytidine Diphosphate Choline; Female; Glyceryl Ethers; Humans; Inflammatory Bowel Diseases; Intestinal Mucosa; Male; Middle Aged; Platelet Activating Factor; Triazoles

1995
Novel antagonists of platelet-activating factor. 1. Synthesis and structure-activity relationships of benzodiazepine and benzazepine derivatives of 2-methyl-1-phenylimidazo[4,5-c]pyridine.
    Journal of medicinal chemistry, 1995, Sep-01, Volume: 38, Issue:18

    Topics: Animals; Azepines; Benzodiazepines; Imidazoles; Mice; Platelet Activating Factor; Pyridines; Rabbits; Structure-Activity Relationship; Thiazoles; Triazoles

1995
Increased prostaglandin I2 and thromboxane A2 production by rat dental pulp after intravenous administration of endotoxin.
    Archives of oral biology, 1994, Volume: 39, Issue:11

    Topics: Animals; Arachidonic Acid; Azepines; Dental Pulp; Endotoxins; Epoprostenol; Escherichia coli; Indomethacin; Injections, Intravenous; Jejunum; Lung; Male; Platelet Activating Factor; Rats; Rats, Wistar; Thromboxane A2; Time Factors; Triazoles

1994
Platelet-activating factor mediates trinitrobenzene induced colitis.
    Prostaglandins, leukotrienes, and essential fatty acids, 1994, Volume: 51, Issue:6

    Topics: 6-Ketoprostaglandin F1 alpha; Animals; Azepines; Colitis; Colon; Dinoprostone; Eicosanoids; Gastrointestinal Contents; Leukotriene B4; Platelet Activating Factor; Rabbits; Second Messenger Systems; Thromboxane B2; Triazoles; Trinitrobenzenesulfonic Acid

1994
Interleukin-1-induced leukocyte extravasation across rat mesenteric microvessels is mediated by platelet-activating factor.
    Blood, 1995, May-01, Volume: 85, Issue:9

    Topics: Animals; Azepines; Cell Adhesion; Chemotaxis, Leukocyte; Dihydropyridines; Edema; Imidazoles; Inflammation; Interleukin-1; Leukocytes; Male; Mesentery; Microcirculation; N-Formylmethionine Leucyl-Phenylalanine; Platelet Activating Factor; Platelet Membrane Glycoproteins; Rats; Rats, Sprague-Dawley; Receptors, Cell Surface; Receptors, G-Protein-Coupled; Recombinant Proteins; Skin; Triazoles

1995
Platelet-activating factor receptor antagonist improves renal function and glomerular lesions in renal ablation.
    The Journal of laboratory and clinical medicine, 1994, Volume: 124, Issue:6

    Topics: Albuminuria; Animals; Azepines; Blood Pressure; Body Weight; Eicosanoids; Inulin; Kidney; Kidney Glomerulus; Male; Nephrectomy; Organ Size; p-Aminohippuric Acid; Platelet Activating Factor; Rats; Rats, Wistar; Triazoles

1994
Evidence for a colonic PAF receptor.
    The Journal of surgical research, 1995, Volume: 58, Issue:1

    Topics: Animals; Azepines; Colon; Eicosanoids; In Vitro Techniques; Platelet Activating Factor; Platelet Membrane Glycoproteins; Rabbits; Receptors, Cell Surface; Receptors, G-Protein-Coupled; Triazoles

1995
Role of R-type calcium channels in the response of the perfused arterial and venous mesenteric vasculature of the rat to platelet-activating factor.
    British journal of pharmacology, 1994, Volume: 112, Issue:4

    Topics: Animals; Arginine; Azepines; Calcium Channels; Isradipine; Male; Mesenteric Arteries; Mesenteric Veins; NG-Nitroarginine Methyl Ester; Perfusion; Platelet Activating Factor; Quinolinium Compounds; Rats; Rats, Wistar; Triazoles

1994
Partial characterization of lipids that develop during the routine storage of blood and prime the neutrophil NADPH oxidase.
    The Journal of laboratory and clinical medicine, 1994, Volume: 124, Issue:5

    Topics: 1-Alkyl-2-acetylglycerophosphocholine Esterase; Acetylation; Azepines; Blood; Blood Preservation; Erythrocytes; Humans; Lipids; Lysophosphatidylcholines; NADH, NADPH Oxidoreductases; NADPH Oxidases; Neutrophils; Oxidoreductases; Phospholipases A; Plasma; Triazoles

1994
Hyperalgesia induced by Bothrops jararaca venom in rats: role of eicosanoids and platelet activating factor (PAF).
    Toxicon : official journal of the International Society on Toxinology, 1994, Volume: 32, Issue:4

    Topics: Animals; Azepines; Bothrops; Crotalid Venoms; Dexamethasone; Diterpenes; Dose-Response Relationship, Drug; Eicosanoids; Fibrinolytic Agents; Ginkgolides; Hyperalgesia; Indomethacin; Lactones; Male; Platelet Activating Factor; Rats; Rats, Wistar; Triazoles

1994
[Lung 3H-thymidine incorporation in monocrotaline (MCT)-treated rats--role of platelet-activating factor (PAF)].
    Nihon Kyobu Shikkan Gakkai zasshi, 1994, Volume: 32, Issue:5

    Topics: Animals; Azepines; DNA; Hypertension, Pulmonary; Lung; Male; Monocrotaline; Platelet Activating Factor; Rats; Rats, Sprague-Dawley; Thymidine; Triazoles

1994
A comparison of the actions of platelet activating factor (PAF) antagonists WEB 2170 and WEB 2086 in the horse.
    Journal of veterinary pharmacology and therapeutics, 1993, Volume: 16, Issue:4

    Topics: Animals; Azepines; Capillary Permeability; Dose-Response Relationship, Drug; Histamine; Horses; Leukocyte Count; Male; Neutrophils; Platelet Activating Factor; Platelet Aggregation; Platelet Aggregation Inhibitors; Skin; Triazoles

1993
Role of platelet-activating factor (PAF) in oxygen radical-induced cardiac dysfunction.
    The Journal of pharmacology and experimental therapeutics, 1994, Volume: 269, Issue:2

    Topics: Animals; Azepines; Free Radicals; Fumarates; Guinea Pigs; Heart; In Vitro Techniques; Myocardium; Platelet Activating Factor; Reactive Oxygen Species; Superoxide Dismutase; Triazoles

1994
Rat liver blood flow after ischemia and reperfusion. The effects of the platelet-activating factor antagonist WEB-2170 and of removing circulating leukocytes.
    Transplantation, 1994, May-27, Volume: 57, Issue:10

    Topics: Animals; Azepines; Liver; Liver Circulation; Male; Neutrophils; Oxyhemoglobins; Platelet Activating Factor; Rats; Rats, Sprague-Dawley; Regional Blood Flow; Reperfusion Injury; Triazoles; Vinblastine

1994
The platelet-activating factor antagonist WEB 2170. Its beneficial effect on dog renal allograft survival.
    Transplantation, 1993, Volume: 56, Issue:4

    Topics: Animals; Azepines; Cyclosporine; Dogs; Drug Therapy, Combination; Graft Survival; Immunosuppression Therapy; Kidney Transplantation; Platelet Activating Factor; Survival Analysis; Transplantation, Homologous; Triazoles

1993
Effect of platelet-activating factor (PAF) receptor blockers on smooth muscle cell replication in vitro and allograft arteriosclerosis in vivo.
    Transplant international : official journal of the European Society for Organ Transplantation, 1993, Volume: 6, Issue:5

    Topics: Animals; Aorta, Thoracic; Arteriosclerosis; Autoradiography; Azepines; Cell Division; Cells, Cultured; DNA; Dose-Response Relationship, Drug; Fibroblasts; Male; Muscle, Smooth, Vascular; Platelet Activating Factor; Platelet Membrane Glycoproteins; Rats; Rats, Inbred WF; Receptors, Cell Surface; Receptors, G-Protein-Coupled; Transplantation, Homologous; Triazoles

1993
Platelet activating factor and histamine effects in synovial blood flow evaluated by laser-Doppler flowmetry.
    The Journal of rheumatology, 1993, Volume: 20, Issue:8

    Topics: Animals; Azepines; Female; Histamine; Laser-Doppler Flowmetry; Male; Platelet Activating Factor; Rabbits; Regional Blood Flow; Synovial Membrane; Triazoles; Vasoconstriction

1993
PAF activation of a voltage-gated R-type Ca2+ channel in human and canine aortic endothelial cells.
    British journal of pharmacology, 1993, Volume: 110, Issue:2

    Topics: Azepines; Calcium Channel Blockers; Calcium Channels; Electrophysiology; Endothelium, Vascular; Fura-2; Humans; Image Processing, Computer-Assisted; In Vitro Techniques; Ion Channel Gating; Isradipine; Male; Platelet Activating Factor; Potassium; Triazoles

1993
Partial agonist effect of the platelet-activating factor receptor antagonists, WEB 2086 and WEB 2170, in the rat perfused heart.
    British journal of pharmacology, 1993, Volume: 110, Issue:2

    Topics: Animals; Azepines; Heart; In Vitro Techniques; Leukotrienes; Perfusion; Platelet Activating Factor; Platelet Membrane Glycoproteins; Radioimmunoassay; Rats; Rats, Sprague-Dawley; Receptors, Cell Surface; Receptors, G-Protein-Coupled; Triazoles; Vasoconstriction; Vasodilation

1993
Transforming growth factor-beta up-regulates the gene expression of the human platelet-activating factor receptor in monocytic and B cell lines.
    Biochemical and biophysical research communications, 1993, Dec-30, Volume: 197, Issue:3

    Topics: Azepines; B-Lymphocytes; Calcium; Cell Line; Cycloheximide; Dactinomycin; Gene Expression; Humans; Ionomycin; Kinetics; Monocytes; Platelet Activating Factor; Platelet Membrane Glycoproteins; Receptors, Cell Surface; Receptors, G-Protein-Coupled; RNA, Messenger; Time Factors; Transcription, Genetic; Transforming Growth Factor beta; Triazoles; Tumor Cells, Cultured; Up-Regulation

1993
Compounds biologically similar to platelet activating factor are present in stored blood components.
    Lipids, 1993, Volume: 28, Issue:5

    Topics: Azepines; Blood Preservation; Gas Chromatography-Mass Spectrometry; Humans; NADH, NADPH Oxidoreductases; NADPH Oxidases; Neutrophils; Platelet Activating Factor; Radioimmunoassay; Triazoles

1993
Experimental otitis media with effusion induced by platelet activating factor.
    The Annals of otology, rhinology, and laryngology, 1993, Volume: 102, Issue:8 Pt 1

    Topics: Animals; Azepines; Chinchilla; Chromatography, High Pressure Liquid; Dose-Response Relationship, Drug; Otitis Media with Effusion; Platelet Activating Factor; Temporal Bone; Time Factors; Triazoles

1993
Role of platelet-activating factor in hypotension and platelet activation induced by infusion of thrombolytic agents in rabbits.
    Circulation research, 1993, Volume: 72, Issue:3

    Topics: Animals; Azepines; Female; Hypotension; Male; Platelet Activating Factor; Platelet Activation; Platelet Aggregation; Platelet Membrane Glycoproteins; Quinolines; Rabbits; Receptors, Cell Surface; Receptors, G-Protein-Coupled; Streptokinase; Tissue Plasminogen Activator; Triazoles

1993
PAF-induced death in NMRI mice--a suitable shock model for testing new PAF receptor antagonists. Correlation with eicosanoid related substances.
    Prostaglandins, leukotrienes, and essential fatty acids, 1993, Volume: 48, Issue:3

    Topics: 4,5-Dihydro-1-(3-(trifluoromethyl)phenyl)-1H-pyrazol-3-amine; Animals; Azepines; Disease Models, Animal; Diterpenes; Eicosanoids; Female; Ginkgolides; Lactones; Masoprocol; Mice; Platelet Activating Factor; Platelet Membrane Glycoproteins; Receptors, Cell Surface; Receptors, G-Protein-Coupled; Shock; Species Specificity; Triazoles

1993
Role of platelet-activating factor in polymorphonuclear neutrophil recruitment in reperfused ischemic rabbit heart.
    The American journal of pathology, 1993, Volume: 142, Issue:2

    Topics: Animals; Azepines; Cell Movement; Female; Heart; Hemodynamics; Male; Myocardial Infarction; Myocardial Ischemia; Myocardial Reperfusion Injury; Myocardium; Neutrophils; Platelet Activating Factor; Quinolines; Rabbits; Risk Factors; Triazoles

1993
Platelet-activating factor: a mediator of pancreatic inflammation during cerulein hyperstimulation.
    The American journal of pathology, 1993, Volume: 142, Issue:5

    Topics: Animals; Azepines; Calcium; Ceruletide; Male; Osmolar Concentration; Pancreas; Pancreatitis; Platelet Activating Factor; Rats; Rats, Sprague-Dawley; Triazoles

1993
Glycogenolytic and haemodynamic responses to bovine serum albumin in isolated perfused livers from sensitized rats.
    The Biochemical journal, 1993, May-15, Volume: 292 ( Pt 1)

    Topics: Animals; Azepines; Calcium; Glycogen; Hemodynamics; Ibuprofen; In Vitro Techniques; Indomethacin; Lactates; Lactic Acid; Liver; Male; Perfusion; Pyruvates; Pyruvic Acid; Rats; Rats, Sprague-Dawley; Serum Albumin, Bovine; Triazoles

1993
Involvement of platelet-activating factor in death following anaphylactic shock in boosted and in unboosted mice.
    European journal of pharmacology, 1993, Apr-22, Volume: 235, Issue:1

    Topics: Anaphylaxis; Animals; Azepines; Immunization, Secondary; Immunoglobulin E; Immunoglobulin G; Male; Mice; Ovalbumin; Platelet Activating Factor; Triazoles; Vaccination

1993
Actions of PAF receptor antagonists in horses with the allergic skin disease sweet itch.
    Inflammation research : official journal of the European Histamine Research Society ... [et al.], 1995, Volume: 44, Issue:10

    Topics: Animals; Azepines; Ceratopogonidae; Dermatitis, Allergic Contact; Edema; Female; Horse Diseases; Horses; Injections, Intradermal; Injections, Intravenous; Insect Bites and Stings; Male; Platelet Aggregation Inhibitors; Platelet Membrane Glycoproteins; Pruritus; Receptors, Cell Surface; Receptors, G-Protein-Coupled; Triazoles

1995
[The roles of platelet activating factor in intestinal mucosal barrier injury after burn].
    Zhonghua wai ke za zhi [Chinese journal of surgery], 1995, Volume: 33, Issue:7

    Topics: Animals; Azepines; Burns; Female; Intestinal Mucosa; Male; Membrane Potentials; Peroxidase; Phospholipases A; Phospholipases A2; Platelet Activating Factor; Platelet Aggregation Inhibitors; Rats; Rats, Wistar; Triazoles

1995
Platelet-activating factor (PAF) receptor antagonism by WEB 2170 improves the survival of ischaemic skeletal muscle.
    Annals of the Academy of Medicine, Singapore, 1995, Volume: 24, Issue:4 Suppl

    Topics: Animals; Azepines; Creatine Kinase; Ischemia; Lipid Peroxidation; Muscle, Skeletal; Neutrophils; Platelet Aggregation Inhibitors; Platelet Membrane Glycoproteins; Rabbits; Receptors, Cell Surface; Receptors, G-Protein-Coupled; Reperfusion Injury; Replantation; Tissue Preservation; Tissue Survival; Triazoles

1995
Analysis of the priming activity of lipids generated during routine storage of platelet concentrates.
    Transfusion, 1996, Volume: 36, Issue:2

    Topics: Adult; Azepines; Blood Platelets; Blood Preservation; Humans; Interleukin-8; Lipids; NADH, NADPH Oxidoreductases; NADPH Oxidases; Platelet Transfusion; Triazoles

1996
Rapid tracheal infusion of surfactant versus bolus instillation in rabbits: effects on oxygenation, blood pressure and surfactant distribution.
    Biology of the neonate, 1996, Volume: 69, Issue:2

    Topics: Animals; Azepines; Blood Pressure; Lung; Oxygen; Platelet Activating Factor; Platelet Aggregation Inhibitors; Rabbits; Surface-Active Agents; Tissue Distribution; Trachea; Triazoles

1996
Induction of IL-4 by platelet-activating factor.
    Clinical and experimental immunology, 1996, Volume: 106, Issue:1

    Topics: Antibodies, Monoclonal; Azepines; Cells, Cultured; Histocompatibility Antigens Class II; Humans; Immunoglobulin A; Interleukin-4; Interleukin-6; Leukocytes, Mononuclear; Lymphocyte Activation; Platelet Activating Factor; Platelet Membrane Glycoproteins; Receptors, Cell Surface; Receptors, G-Protein-Coupled; Triazoles

1996
Plasmin promotes an endothelium-dependent adhesion of neutrophils. Involvement of platelet activating factor and P-selectin.
    Circulation, 1996, Jun-15, Volume: 93, Issue:12

    Topics: Animals; Antibodies; Antibodies, Monoclonal; Azepines; Capillary Permeability; Cattle; CD18 Antigens; Cell Adhesion; Endothelium, Vascular; Fibrinolysin; Humans; Neutrophils; P-Selectin; Platelet Activating Factor; Platelet Membrane Glycoproteins; Receptors, Cell Surface; Receptors, G-Protein-Coupled; Streptokinase; Tissue Plasminogen Activator; Triazoles

1996
Different classes of PAF-antagonists block norepinephrine-induced vascular escape and tachyphylaxis in the isolated rabbit kidney.
    Research communications in molecular pathology and pharmacology, 1996, Volume: 94, Issue:2

    Topics: Animals; Azepines; Dihydropyridines; Ginkgolides; In Vitro Techniques; Kidney; Lactones; Norepinephrine; Platelet Activating Factor; Rabbits; Tachyphylaxis; Triazoles; Vasoconstriction

1996
Angiogenesis induced in vivo by hepatocyte growth factor is mediated by platelet-activating factor synthesis from macrophages.
    Journal of immunology (Baltimore, Md. : 1950), 1997, Feb-01, Volume: 158, Issue:3

    Topics: Animals; Azepines; Cattle; Cell Movement; Cells, Cultured; Chemotaxis, Leukocyte; Collagen; Drug Combinations; Hepatocyte Growth Factor; Humans; Laminin; Macrophages, Peritoneal; Mice; Mice, Inbred C57BL; Neovascularization, Physiologic; Phosphotyrosine; Platelet Activating Factor; Platelet Membrane Glycoproteins; Proteoglycans; Proto-Oncogene Mas; Proto-Oncogene Proteins c-met; Receptor Protein-Tyrosine Kinases; Receptors, Cell Surface; Receptors, G-Protein-Coupled; Signal Transduction; Triazoles

1997
Acute lethal toxicity following passive immunization for treatment of murine cryptococcosis.
    Infection and immunity, 1997, Volume: 65, Issue:5

    Topics: Animals; Antibodies, Monoclonal; Antigen-Antibody Complex; Azepines; Chlorpheniramine; Chlorpromazine; Clodronic Acid; Complement System Proteins; Cryptococcosis; Dexamethasone; Elapid Venoms; Epinephrine; Female; Immunization, Passive; Immunoglobulin Isotypes; Kidney; Liver; Lung; Mice; Mice, Inbred BALB C; Mice, Inbred C3H; Mice, Inbred C57BL; Mice, Inbred DBA; Polysaccharides; Shock; Specific Pathogen-Free Organisms; Triazoles; Tumor Necrosis Factor-alpha

1997
The platelet-activating factor receptor antagonist WEB 2170 prevents neonatal necrotizing enterocolitis in rats.
    Journal of pediatric gastroenterology and nutrition, 1997, Volume: 24, Issue:3

    Topics: Animals; Animals, Newborn; Azepines; Enterocolitis, Pseudomembranous; Intestinal Mucosa; Intestine, Small; Necrosis; Platelet Activating Factor; Platelet Aggregation Inhibitors; Platelet Membrane Glycoproteins; Rats; Rats, Sprague-Dawley; Receptors, Cell Surface; Receptors, G-Protein-Coupled; Triazoles

1997
Laser Doppler perfusion imaging: new technique for determination of perfusion and reperfusion of splanchnic organs and tumor tissue.
    Lasers in surgery and medicine, 1997, Volume: 20, Issue:4

    Topics: Aminolevulinic Acid; Animals; Azepines; Intestines; Ischemia; Laser-Doppler Flowmetry; Liver; Liver Neoplasms; Pancreas; Photochemotherapy; Platelet Aggregation Inhibitors; Rats; Rats, Wistar; Regional Blood Flow; Splanchnic Circulation; Spleen; Stomach; Triazoles

1997
Platelet-activating factor and oxidized LDL induce immune activation by a common mechanism.
    Arteriosclerosis, thrombosis, and vascular biology, 1997, Volume: 17, Issue:5

    Topics: Azepines; Humans; Immunity; Interferon-gamma; Leukocytes, Mononuclear; Lipoproteins, LDL; Oxidation-Reduction; Platelet Activating Factor; Platelet Aggregation Inhibitors; Platelet Membrane Glycoproteins; Receptors, Cell Surface; Receptors, G-Protein-Coupled; Triazoles; Tumor Necrosis Factor-alpha

1997
Studies of the nature of the binding by albumin of platelet-activating factor released from cells.
    The Journal of biological chemistry, 1997, Jul-25, Volume: 272, Issue:30

    Topics: 1-Alkyl-2-acetylglycerophosphocholine Esterase; Animals; Azepines; Biological Availability; Blastocyst; Calcimycin; Cattle; Dithiothreitol; Electrophoresis, Polyacrylamide Gel; Endothelium, Vascular; Humans; Ionophores; Mice; Pepsin A; Peptide Mapping; Phospholipases A; Platelet Activating Factor; Platelet Aggregation Inhibitors; Protein Binding; Protein Conformation; Serum Albumin; Serum Albumin, Bovine; Sulfhydryl Reagents; Triazoles; Trypsin

1997
Nitric oxide mediates angiogenesis induced in vivo by platelet-activating factor and tumor necrosis factor-alpha.
    The American journal of pathology, 1997, Volume: 151, Issue:2

    Topics: Animals; Azepines; Cell Movement; Endothelium, Vascular; Enzyme Inhibitors; Female; Humans; Mice; Mice, Inbred C57BL; Neovascularization, Physiologic; NG-Nitroarginine Methyl Ester; Nitric Oxide; Platelet Activating Factor; Triazoles; Tumor Necrosis Factor-alpha

1997
[A study on changes and its mechanisms of intestinal mucosal permeability after severe burn].
    Zhonghua zheng xing shao shang wai ke za zhi = Zhonghua zheng xing shao shang waikf [i.e. waike] zazhi = Chinese journal of plastic surgery and burns, 1996, Volume: 12, Issue:5

    Topics: Animals; Azepines; Burns; Female; Intestinal Mucosa; Male; Permeability; Platelet Activating Factor; Platelet Aggregation Inhibitors; Rats; Rats, Wistar; Technetium Tc 99m Pentetate; Triazoles

1996
Lung oedema induced by Tityus serrulatus scorpion venom in the rat.
    Comparative biochemistry and physiology. Part C, Pharmacology, toxicology & endocrinology, 1997, Volume: 118, Issue:2

    Topics: Animals; Aprotinin; Azepines; Capillary Permeability; Cyclooxygenase Inhibitors; Diterpenes; Drug Interactions; Fibrinolytic Agents; Ginkgolides; Hemostatics; Heparin; Hypertension; Injections, Intravenous; Lactones; Leukotrienes; Lipoxygenase Inhibitors; Lung; Male; Masoprocol; Platelet Activating Factor; Platelet Aggregation Inhibitors; Prostaglandins; Pulmonary Edema; Rats; Rats, Wistar; Scorpion Venoms; Triazoles

1997
Platelet-activating factor mediates monocyte chemoattractant protein-1 expression in glomerular immune injury.
    Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association, 1998, Volume: 13, Issue:1

    Topics: Animals; Azepines; Chemokine CCL2; Complement System Proteins; Glomerulonephritis; Kidney Glomerulus; Male; Platelet Activating Factor; Polymerase Chain Reaction; Rabbits; Rats; Rats, Wistar; RNA, Messenger; Triazoles

1998
Investigation of the effects of platelet-activating factor (PAF) on ion transport and prostaglandin synthesis in human colonic mucosa in vitro.
    British journal of pharmacology, 1998, Volume: 123, Issue:2

    Topics: Azepines; Biological Transport; Colon; Humans; Intestinal Mucosa; Ions; Membrane Potentials; Platelet Activating Factor; Platelet Aggregation Inhibitors; Platelet Membrane Glycoproteins; Prostaglandins; Receptors, Cell Surface; Receptors, G-Protein-Coupled; Triazoles

1998
Plasma and lipids from stored packed red blood cells cause acute lung injury in an animal model.
    The Journal of clinical investigation, 1998, Apr-01, Volume: 101, Issue:7

    Topics: Acute Disease; Adult; Animals; Azepines; Benzimidazoles; Blood Preservation; Blood Pressure; Calcium; Calcium Channel Blockers; Humans; Leukotriene E4; Lipids; Lung Diseases; Lysophosphatidylcholines; Male; Mibefradil; Neutrophil Activation; Neutrophils; Platelet Aggregation Inhibitors; Pulmonary Artery; Pulmonary Edema; Rats; Rats, Sprague-Dawley; Tetrahydronaphthalenes; Transfusion Reaction; Triazoles

1998
Magnesium deficiency-dependent audiogenic seizures (MDDASs) in adult mice: a nutritional model for discriminatory screening of anticonvulsant drugs and original assessment of neuroprotection properties.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 1998, Jun-01, Volume: 18, Issue:11

    Topics: Acoustic Stimulation; Animals; Anticonvulsants; Azepines; Brain Chemistry; Disease Models, Animal; Dose-Response Relationship, Drug; Electroshock; Epilepsy; gamma-Aminobutyric Acid; Locomotion; Magnesium Deficiency; Melatonin; Mice; Mice, Inbred BALB C; Mice, Inbred C3H; Mice, Inbred C57BL; Mice, Inbred CBA; Mice, Inbred DBA; Neuroprotective Agents; Platelet Aggregation Inhibitors; Triazoles

1998
Effects of platelet-activating factor on intracellular Ca2+ concentration and contractility in isolated cardiomyocytes.
    Journal of cardiovascular pharmacology, 1998, Volume: 31, Issue:5

    Topics: Analysis of Variance; Animals; Azepines; Calcium; Male; Myocardial Contraction; Myocardium; Platelet Activating Factor; Platelet Aggregation Inhibitors; Rats; Rats, Wistar; Triazoles

1998
Platelet-activating factor modulates pulmonary vasomotor tone in the perinatal lamb.
    Journal of applied physiology (Bethesda, Md. : 1985), 1998, Volume: 85, Issue:3

    Topics: Angiotensin II; Animals; Animals, Newborn; Azepines; Blood Pressure; Female; Muscle Tonus; Muscle, Smooth, Vascular; Platelet Activating Factor; Platelet Aggregation Inhibitors; Platelet Membrane Glycoproteins; Pregnancy; Pulmonary Circulation; Receptors, Cell Surface; Receptors, G-Protein-Coupled; Sheep; Triazoles; Vascular Resistance; Vasoconstrictor Agents

1998
Lipid mediators, tumor necrosis factor and nitric oxide and their interactions in immune-complex-induced lung injury.
    European journal of pharmacology, 1998, Sep-25, Volume: 358, Issue:1

    Topics: Animals; Azepines; Bronchoalveolar Lavage Fluid; Immune Complex Diseases; Leukotriene B4; Lung; Male; Neutrophils; Nitric Oxide; Platelet Aggregation Inhibitors; Rats; Rats, Wistar; Triazoles; Tumor Necrosis Factor-alpha

1998
Modulation by lipid mediators of immune complex-induced lung inflammation in mice.
    European journal of pharmacology, 1998, Nov-13, Volume: 361, Issue:1

    Topics: Animals; Antigen-Antibody Complex; Arthus Reaction; Azepines; Benzopyrans; Blood Vessels; Bronchoalveolar Lavage Fluid; Capillary Permeability; Dose-Response Relationship, Drug; Eicosanoids; Hemoglobins; Immune Complex Diseases; Indoles; Indomethacin; Lipoxygenase Inhibitors; Lung; Male; Mice; Mice, Inbred BALB C; Mice, Inbred C3H; Neutrophils; Peroxidase; Platelet Activating Factor; Platelet Aggregation Inhibitors; Pneumonia; Receptors, Leukotriene B4; Species Specificity; Triazoles

1998
Xenogeneic rejection mechanisms shown by intravital microscopy.
    Transplantation proceedings, 1998, Volume: 30, Issue:8

    Topics: Animals; Azepines; Bile; Blood Pressure; Blood Transfusion; Elapid Venoms; Graft Rejection; Humans; Liver Circulation; Microcirculation; Microscopy, Fluorescence; Platelet Activating Factor; Rats; Rats, Sprague-Dawley; Transplantation, Heterologous; Transplantation, Isogeneic; Triazoles

1998
Interleukin-12 is synthesized by mesangial cells and stimulates platelet-activating factor synthesis, cytoskeletal reorganization, and cell shape change.
    The American journal of pathology, 1999, Volume: 154, Issue:2

    Topics: Angiotensin II; Azepines; Cell Size; Cells, Cultured; Cytoskeleton; Dose-Response Relationship, Drug; Glomerular Mesangium; Humans; Interleukin-12; Interleukin-8; Lipopolysaccharides; Platelet Activating Factor; Platelet Aggregation Inhibitors; Receptors, Interleukin; Receptors, Interleukin-12; RNA, Messenger; Superoxides; Time Factors; Triazoles; Tumor Necrosis Factor-alpha

1999
Influence of platelet-activating factor on cerebral microcirculation in rats: part 1. Systemic application.
    Stroke, 1999, Volume: 30, Issue:4

    Topics: Animals; Azepines; Blood Pressure; Blood-Brain Barrier; Carbon Dioxide; Cell Communication; Cerebrovascular Circulation; Endothelium, Vascular; Hematocrit; Hydrogen-Ion Concentration; Leukocyte Count; Leukocytes; Male; Microcirculation; Microscopy, Fluorescence; Platelet Activating Factor; Platelet Aggregation Inhibitors; Rats; Rats, Sprague-Dawley; Triazoles

1999
Influence of platelet-activating factor on cerebral microcirculation in rats: part 2. Local application.
    Stroke, 1999, Volume: 30, Issue:4

    Topics: Animals; Azepines; Blood Pressure; Blood-Brain Barrier; Cell Communication; Cerebrovascular Circulation; Dose-Response Relationship, Drug; Endothelium, Vascular; Leukocytes; Male; Microcirculation; Microscopy, Fluorescence; Pia Mater; Platelet Activating Factor; Platelet Aggregation Inhibitors; Rats; Rats, Sprague-Dawley; Triazoles

1999
Thrombopoietin stimulates endothelial cell motility and neoangiogenesis by a platelet-activating factor-dependent mechanism.
    Circulation research, 1999, Apr-16, Volume: 84, Issue:7

    Topics: Animals; Azepines; Biocompatible Materials; Biological Transport; Cell Division; Cell Movement; Cell Nucleus; Cells, Cultured; Collagen; DNA-Binding Proteins; Drug Combinations; Endothelium, Vascular; Fibroblast Growth Factor 2; Gene Expression; Humans; Interleukin-8; Kinetics; Laminin; Mice; Milk Proteins; Neoplasm Proteins; Neovascularization, Physiologic; Phosphorylation; Platelet Activating Factor; Platelet Aggregation Inhibitors; Proteoglycans; Proto-Oncogene Proteins; Receptors, Cytokine; Receptors, Thrombopoietin; Signal Transduction; STAT1 Transcription Factor; STAT5 Transcription Factor; Thrombopoietin; Trans-Activators; Triazoles; Tyrosine; Umbilical Veins

1999
Effect of platelet activating factor and its antagonist on the mucociliary clearance of the eustachian tube in guinea pigs.
    The Annals of otology, rhinology, and laryngology, 1999, Volume: 108, Issue:5

    Topics: Animals; Azepines; Cilia; Coloring Agents; Dose-Response Relationship, Drug; Epithelium; Eustachian Tube; Guinea Pigs; Microscopy, Electron; Mucociliary Clearance; Otitis Media with Effusion; Platelet Activating Factor; Rosaniline Dyes; Triazoles

1999
The synthesis of platelet-activating factor modulates chemotaxis of monocytes induced by HIV-1 Tat.
    European journal of immunology, 1999, Volume: 29, Issue:5

    Topics: Azepines; Chemotaxis; Gene Products, tat; HIV-1; Humans; Monocytes; Phospholipid Ethers; Platelet Activating Factor; Platelet Aggregation Inhibitors; Platelet Membrane Glycoproteins; Receptors, Cell Surface; Receptors, G-Protein-Coupled; tat Gene Products, Human Immunodeficiency Virus; Triazoles

1999
Role of thromboxane A2 and platelet activating factor in early haemodynamic response to lipopolysaccharide in rats.
    Journal of physiology and pharmacology : an official journal of the Polish Physiological Society, 1999, Volume: 50, Issue:2

    Topics: Animals; Azepines; Blood Pressure; Enzyme Inhibitors; Escherichia coli; Indans; Lipopolysaccharides; Male; Platelet Activating Factor; Platelet Aggregation Inhibitors; Rats; Rats, Wistar; Thromboxane A2; Triazoles

1999
Role of nitric oxide and platelet-activating factor in cardiac alterations induced by tumor necrosis factor-alpha in the guinea-pig papillary muscle.
    Cardiovascular research, 1999, Volume: 41, Issue:3

    Topics: Action Potentials; Adrenergic beta-Antagonists; Analysis of Variance; Animals; Azepines; Cyclooxygenase Inhibitors; Depression, Chemical; Guinea Pigs; Heart; In Vitro Techniques; Indomethacin; Myocardial Contraction; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Phospholipid Ethers; Platelet Activating Factor; Platelet Aggregation Inhibitors; Propranolol; Triazoles; Tumor Necrosis Factor-alpha

1999
Human IL-3 stimulates endothelial cell motility and promotes in vivo new vessel formation.
    Journal of immunology (Baltimore, Md. : 1950), 1999, Aug-15, Volume: 163, Issue:4

    Topics: Animals; Apolipoproteins; Apolipoproteins D; Azepines; Carrier Proteins; Cell Division; Cell Line; Cell Movement; DNA-Binding Proteins; Endothelium, Vascular; Female; Glycoproteins; Humans; Injections, Subcutaneous; Interleukin-3; Macromolecular Substances; Membrane Transport Proteins; Mice; Mice, Inbred C57BL; Milk Proteins; Neovascularization, Physiologic; Platelet Activating Factor; Platelet Membrane Glycoproteins; Protein Binding; Receptors, Cell Surface; Receptors, G-Protein-Coupled; Receptors, Interleukin-3; STAT5 Transcription Factor; Trans-Activators; Triazoles; Tumor Suppressor Proteins

1999
Effects of tachykinin NK1 or PAF receptor blockade on the lung injury induced by scorpion venom in rats.
    European journal of pharmacology, 1999, Jul-09, Volume: 376, Issue:3

    Topics: Animals; Azepines; Biphenyl Compounds; Guinea Pigs; Ileum; Male; Platelet Membrane Glycoproteins; Rats; Rats, Wistar; Receptors, Cell Surface; Receptors, G-Protein-Coupled; Receptors, Tachykinin; Respiratory Distress Syndrome; Scorpion Venoms; Triazoles

1999
Suppression of lipopolysaccharide-induced nitric oxide synthase expression by platelet-activating factor receptor antagonists in the rat liver and cultured rat Kupffer cells.
    Hepatology (Baltimore, Md.), 1999, Volume: 30, Issue:5

    Topics: Alanine Transaminase; Animals; Azepines; Cell Nucleus; Cells, Cultured; Cytoplasm; DNA-Binding Proteins; Endotoxemia; Gene Expression Regulation, Enzymologic; I-kappa B Proteins; Kupffer Cells; Lipopolysaccharides; Liver; Male; NF-kappa B; NF-KappaB Inhibitor alpha; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Platelet Activating Factor; Rats; Rats, Sprague-Dawley; RNA, Messenger; Transcription, Genetic; Triazoles

1999
Motility induced by human immunodeficiency virus-1 Tat on Kaposi's sarcoma cells requires platelet-activating factor synthesis.
    The American journal of pathology, 1999, Volume: 155, Issue:5

    Topics: Azepines; Cell Movement; Diterpenes; Dose-Response Relationship, Drug; Fibrinolytic Agents; Gene Products, tat; Ginkgolides; HIV-1; Humans; Lactones; Phospholipid Ethers; Platelet Activating Factor; Platelet Aggregation Inhibitors; Platelet Membrane Glycoproteins; Pyridinium Compounds; Receptors, Cell Surface; Receptors, G-Protein-Coupled; Sarcoma, Kaposi; tat Gene Products, Human Immunodeficiency Virus; Triazoles; Tumor Cells, Cultured

1999
Endotoxaemia in rats: role of NO, PAF and TXA2 in pulmonary neutrophil sequestration and hyperlactataemia.
    Journal of physiology and pharmacology : an official journal of the Polish Physiological Society, 1999, Volume: 50, Issue:3

    Topics: Animals; Azepines; Cell Movement; Endotoxemia; Indans; Lactic Acid; Lipopolysaccharides; Lung; Male; Neutrophils; NG-Nitroarginine Methyl Ester; Nitric Oxide; Platelet Activating Factor; Platelet Membrane Glycoproteins; Rats; Rats, Wistar; Receptors, Cell Surface; Receptors, G-Protein-Coupled; Thromboxane A2; Triazoles

1999
Platelet-activating factor enhances vascular endothelial growth factor-induced endothelial cell motility and neoangiogenesis in a murine matrigel model.
    Arteriosclerosis, thrombosis, and vascular biology, 2000, Volume: 20, Issue:1

    Topics: Animals; Azepines; Cell Movement; Cells, Cultured; Endothelial Growth Factors; Endothelium, Vascular; Female; Humans; In Vitro Techniques; Lymphokines; Mice; Mice, Inbred C57BL; Neovascularization, Physiologic; Phospholipid Ethers; Platelet Activating Factor; Platelet Membrane Glycoproteins; Receptors, Cell Surface; Receptors, G-Protein-Coupled; Skin; Triazoles; Vascular Endothelial Growth Factor A; Vascular Endothelial Growth Factors

2000
Lipopolysaccharide activates nuclear factor kappaB in rat intestine: role of endogenous platelet-activating factor and tumour necrosis factor.
    British journal of pharmacology, 2000, Volume: 129, Issue:2

    Topics: Animals; Antibodies, Blocking; Azepines; Cell Nucleus; Electrophoresis; Epithelial Cells; Ileum; Immunohistochemistry; Intestinal Mucosa; Intestines; Lipopolysaccharides; Male; Neutrophils; NF-kappa B; Platelet Activating Factor; Platelet Aggregation Inhibitors; Rats; Rats, Sprague-Dawley; Triazoles; Tumor Necrosis Factor-alpha

2000
Inhibition of the hyperalgesic activity of Bothrops jararaca venom by an antibothropic fraction isolated from opossum (Didelphis marsupialis) serum.
    Toxicon : official journal of the International Society on Toxinology, 2000, Volume: 38, Issue:6

    Topics: Animals; Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non-Steroidal; Antivenins; Azepines; Bothrops; Crotalid Venoms; Dexamethasone; Hyperalgesia; Indomethacin; Opossums; Platelet Aggregation Inhibitors; Triazoles

2000
Platelet-activating factor increases mucosal permeability in rat intestine via tyrosine phosphorylation of E-cadherin.
    British journal of pharmacology, 2000, Volume: 129, Issue:7

    Topics: Animals; Azepines; Cadherins; Cytoskeleton; Dextrans; Enzyme Inhibitors; Epithelium; Glucose; Hypotension; Intestinal Mucosa; Intestines; Leukocytosis; Male; Permeability; Phosphorylation; Phosphotyrosine; Platelet Activating Factor; Protein-Tyrosine Kinases; Quinolinium Compounds; Rats; Rats, Sprague-Dawley; Triazoles; Tyrosine; Tyrphostins

2000
The expression and localization of plasma platelet-activating factor acetylhydrolase in endotoxemic rats.
    The Journal of biological chemistry, 2000, Jun-30, Volume: 275, Issue:26

    Topics: 1-Alkyl-2-acetylglycerophosphocholine Esterase; Animals; Azepines; DNA, Complementary; Endotoxemia; Endotoxins; Kupffer Cells; Leukocytes; Lipopolysaccharides; Liver; Macrophages, Peritoneal; Male; Phospholipases A; Platelet Activating Factor; Platelet Aggregation Inhibitors; Rats; Rats, Sprague-Dawley; Signal Transduction; Sodium Chloride; Tissue Distribution; Triazoles; Up-Regulation

2000
Activation of platelet-activating factor (PAF) receptor stimulates nitric oxide (NO) release via protein kinase C-alpha in HEC-1B human endometrial epithelial cell line.
    Molecular medicine (Cambridge, Mass.), 2000, Volume: 6, Issue:1

    Topics: Azepines; Calcium; Cell Line; Endometrium; Enzyme Activation; Epithelial Cells; Female; Humans; Indoles; Infertility, Female; Isoenzymes; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Nitric Oxide Synthase Type III; omega-N-Methylarginine; Platelet Activating Factor; Platelet Membrane Glycoproteins; Protein Kinase C; Protein Kinase C-alpha; Receptors, Cell Surface; Receptors, G-Protein-Coupled; Signal Transduction; Triazoles

2000
Effect of WEB 2170 BS, platelet activating factor receptor inhibitor, in the guinea pig model of middle ear inflammation.
    The Annals of otology, rhinology, and laryngology, 2000, Volume: 109, Issue:6

    Topics: Animals; Azepines; Disease Models, Animal; Ear, Middle; Guinea Pigs; Otitis Media; Peroxidase; Platelet Aggregation Inhibitors; Platelet Membrane Glycoproteins; Receptors, Cell Surface; Receptors, G-Protein-Coupled; Staphylococcal Infections; Temporal Bone; Triazoles

2000
Reduction of hypoxic-ischemic brain swelling in the neonatal rat with PAF antagonist WEB 2170: lack of long-term protection.
    Pediatric research, 2000, Volume: 48, Issue:1

    Topics: Animals; Animals, Newborn; Atrophy; Azepines; Brain; Brain Edema; Female; Hypoxia-Ischemia, Brain; Male; Platelet Activating Factor; Platelet Aggregation Inhibitors; Rats; Rats, Wistar; Triazoles; Weight Gain

2000
Synthesis and pharmacological evaluation of novel heterotricyclic acylhydrazone derivatives, designed as PAF antagonists.
    European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences, 2000, Volume: 11, Issue:4

    Topics: Animals; Azepines; Models, Molecular; Platelet Activating Factor; Platelet Aggregation Inhibitors; Rabbits; Triazoles

2000
PAF produced by human breast cancer cells promotes migration and proliferation of tumor cells and neo-angiogenesis.
    The American journal of pathology, 2000, Volume: 157, Issue:5

    Topics: Animals; Azepines; Breast Neoplasms; Cell Division; Cell Movement; Female; Humans; Mice; Mice, SCID; Neoplasm Transplantation; Neovascularization, Pathologic; Phospholipid Ethers; Platelet Activating Factor; Platelet Aggregation Inhibitors; Platelet Membrane Glycoproteins; Receptors, Cell Surface; Receptors, G-Protein-Coupled; Triazoles; Tumor Cells, Cultured

2000
Role of NO and PAF in the impairment of skeletal muscle contractility induced by TNF-alpha.
    American journal of physiology. Regulatory, integrative and comparative physiology, 2000, Volume: 279, Issue:6

    Topics: Animals; Azepines; Guinea Pigs; In Vitro Techniques; Muscle Contraction; Muscle, Skeletal; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Donors; Penicillamine; Phospholipases A; Platelet Activating Factor; S-Nitroso-N-Acetylpenicillamine; Stereoisomerism; Triazoles; Tumor Necrosis Factor-alpha

2000
Effects of the PAF receptor antagonist UK74505 on local and remote reperfusion injuries following ischaemia of the superior mesenteric artery in the rat.
    British journal of pharmacology, 2000, Volume: 131, Issue:8

    Topics: Animals; Azepines; Capillary Permeability; Dihydropyridines; Disease Models, Animal; Dose-Response Relationship, Drug; Imidazoles; Intestine, Small; Male; Mesenteric Artery, Superior; Neutrophils; Platelet Aggregation Inhibitors; Platelet Membrane Glycoproteins; Polysaccharides; Rats; Rats, Wistar; Receptors, Cell Surface; Receptors, G-Protein-Coupled; Reperfusion Injury; Triazoles; Tumor Necrosis Factor-alpha

2000
Tat-induced platelet-activating factor synthesis contributes to the angiogenic effect of HIV-1 Tat.
    European journal of immunology, 2001, Volume: 31, Issue:2

    Topics: Angiogenesis Inducing Agents; Animals; Azepines; Cell Movement; Endothelium, Vascular; Female; Gene Products, tat; HIV-1; Humans; Mice; Mice, Inbred C57BL; Platelet Activating Factor; tat Gene Products, Human Immunodeficiency Virus; Triazoles

2001
Specific PAF antagonist WEB-2086 induces terminal differentiation of murine and human leukemia cells.
    FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 2002, Volume: 16, Issue:7

    Topics: Animals; Antineoplastic Agents; Azepines; Cell Differentiation; Cell Division; Dose-Response Relationship, Drug; Gene Expression Regulation, Neoplastic; Histones; HL-60 Cells; Humans; K562 Cells; Kinetics; Leukemia; Leukemia, Erythroblastic, Acute; Mice; Phospholipid Ethers; Platelet Activating Factor; Platelet Membrane Glycoproteins; Receptors, Cell Surface; Receptors, G-Protein-Coupled; RNA, Neoplasm; Tetradecanoylphorbol Acetate; Triazoles; Tumor Cells, Cultured

2002
PAF antagonist treatment reduces pro-inflammatory cytokine mRNA after spinal cord injury.
    Neuroreport, 2002, Jan-21, Volume: 13, Issue:1

    Topics: Animals; Azepines; Cytokines; Female; Inflammation Mediators; Platelet Activating Factor; Platelet Aggregation Inhibitors; Rats; Rats, Long-Evans; RNA, Messenger; Spinal Cord Injuries; Thoracic Vertebrae; Time Factors; Triazoles

2002
Platelet-activating factor induces cell death in cultured astrocytes and oligodendrocytes: involvement of caspase-3.
    Glia, 2002, Volume: 38, Issue:3

    Topics: Animals; Animals, Newborn; Antigens, Differentiation; Astrocytes; Azepines; Caspase 3; Caspases; Cell Death; Cells, Cultured; Central Nervous System; Diterpenes; Dose-Response Relationship, Drug; Free Radical Scavengers; Ginkgolides; Glial Fibrillary Acidic Protein; Inflammation; Lactones; Mice; Mice, Inbred CBA; Oligodendroglia; Platelet Activating Factor; Platelet Aggregation Inhibitors; Platelet Membrane Glycoproteins; Receptors, Cell Surface; Receptors, G-Protein-Coupled; Spinal Cord Injuries; Triazoles

2002
Neutrophil apoptosis is delayed by trauma patients' plasma via a mechanism involving proinflammatory phospholipids and protein kinase C.
    Surgical infections, 2001,Winter, Volume: 2, Issue:4

    Topics: Adolescent; Adult; Aged; Apoptosis; Azepines; Enzyme Inhibitors; Humans; In Vitro Techniques; Indoles; Injury Severity Score; Maleimides; Middle Aged; Neutrophils; Phospholipids; Plasma; Platelet Activating Factor; Platelet Aggregation Inhibitors; Protein Kinase C; Signal Transduction; Time Factors; Triazoles; Wounds and Injuries

2001
Platelet-activating factor antagonist WEB-2170 inhibits lipopolysaccharide-induced, but not antiprogestin-induced, preterm cervical ripening in timed-pregnant rats.
    American journal of obstetrics and gynecology, 2003, Volume: 189, Issue:4

    Topics: Animals; Azepines; Cervical Ripening; Female; Hormone Antagonists; Lipopolysaccharides; Mifepristone; Obstetric Labor, Premature; Platelet Aggregation Inhibitors; Pregnancy; Progestins; Rats; Rats, Sprague-Dawley; Triazoles

2003
Platelet-activating factor mediates CD40-dependent angiogenesis and endothelial-smooth muscle cell interaction.
    Journal of immunology (Baltimore, Md. : 1950), 2003, Nov-15, Volume: 171, Issue:10

    Topics: Animals; Antibodies, Monoclonal; Azepines; CD40 Antigens; CD40 Ligand; Cell Communication; Cell Movement; Cells, Cultured; Collagen; Drug Combinations; Endothelium, Vascular; Female; Humans; Injections, Subcutaneous; Intracellular Fluid; Laminin; Mice; Mice, Inbred C57BL; Models, Immunological; Muscle, Smooth, Vascular; Neovascularization, Physiologic; Platelet Activating Factor; Platelet Membrane Glycoproteins; Proteoglycans; Receptors, G-Protein-Coupled; Triazoles

2003
Phosphoinositide 3-kinase gamma-deficient hearts are protected from the PAF-dependent depression of cardiac contractility.
    Cardiovascular research, 2003, Nov-01, Volume: 60, Issue:2

    Topics: Animals; Azepines; Class Ib Phosphatidylinositol 3-Kinase; Female; In Vitro Techniques; Isoenzymes; Mice; Mice, Knockout; Myocardial Contraction; Myocardial Reperfusion Injury; Myocardium; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; omega-N-Methylarginine; Perfusion; Phosphatidylinositol 3-Kinases; Platelet Activating Factor; Platelet Aggregation Inhibitors; Platelet Membrane Glycoproteins; Receptors, G-Protein-Coupled; Signal Transduction; Triazoles

2003
Candidate's thesis: Platelet-activating factor-induced hearing loss: mediated by nitric oxide?
    The Laryngoscope, 2003, Volume: 113, Issue:12

    Topics: Animals; Azepines; Cochlea; Evoked Potentials, Auditory, Brain Stem; Guinea Pigs; Hair Cells, Auditory; Hearing Loss; Immunohistochemistry; Longitudinal Studies; Microscopy, Electron, Scanning; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Platelet Activating Factor; Random Allocation; Round Window, Ear; Triazoles

2003
Effect of inhibitors of leukotriene and/or platelet activating factor on killed H. influenzae induced experimental otitis media with effusion.
    International journal of pediatric otorhinolaryngology, 2004, Volume: 68, Issue:1

    Topics: Animals; Arachidonic Acid; Azepines; Case-Control Studies; Chinchilla; Chromatography, High Pressure Liquid; Haemophilus influenzae; Injections, Intraperitoneal; Leukotriene Antagonists; Leukotrienes; Naphthyridines; Otitis Media with Effusion; Platelet Activating Factor; Platelet Aggregation Inhibitors; Random Allocation; Temporal Bone; Triazoles

2004
The role of platelet activating factor in a neonatal piglet model of necrotising enterocolitis.
    Gut, 2004, Volume: 53, Issue:2

    Topics: Animals; Animals, Newborn; Azepines; Blood Gas Analysis; Blood Pressure; Enterocolitis, Necrotizing; Hypoxia; Intestinal Mucosa; Lipopolysaccharides; Mesenteric Arteries; Models, Animal; Platelet Activating Factor; Regional Blood Flow; Swine; Triazoles; Vascular Resistance

2004
Effect of platelet activating factor with and without receptor antagonist (WEB2170) on morphology of isolated cochlear outer hair cells.
    The Annals of otology, rhinology, and laryngology, 2004, Volume: 113, Issue:2

    Topics: Albumins; Animals; Azepines; Chinchilla; Hair Cells, Auditory, Outer; Platelet Activating Factor; Sodium Chloride; Triazoles

2004
Involvement of platelet activating factor in immediate heart response to lipopolysaccharide.
    Journal of physiology and pharmacology : an official journal of the Polish Physiological Society, 2004, Volume: 55, Issue:2

    Topics: Animals; Azepines; Cell Line; Dose-Response Relationship, Drug; Enzyme Induction; Escherichia coli; Lipopolysaccharides; Macrophages; Membrane Proteins; Mice; Myocardial Contraction; Myocardium; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Phospholipid Ethers; Platelet Activating Factor; Rats; Receptors, Leukotriene; Receptors, Thromboxane A2, Prostaglandin H2; Triazoles

2004
Effect of WEB 2170 BS, platelet activating factor receptor inhibitor, in the rabbit model of sinusitis.
    The Annals of otology, rhinology, and laryngology, 2004, Volume: 113, Issue:6

    Topics: Animals; Azepines; Disease Models, Animal; Maxillary Sinus; Maxillary Sinusitis; Mucous Membrane; Nitric Oxide; Nitric Oxide Synthase; Platelet Aggregation Inhibitors; Rabbits; Triazoles

2004
Platelet-activating factor induces cardioprotection in isolated rat heart akin to ischemic preconditioning: role of phosphoinositide 3-kinase and protein kinase C activation.
    American journal of physiology. Heart and circulatory physiology, 2005, Volume: 288, Issue:5

    Topics: Alkaloids; Animals; Azepines; Benzophenanthridines; Cardiotonic Agents; Chromones; Coronary Circulation; Enzyme Inhibitors; In Vitro Techniques; Ischemic Preconditioning, Myocardial; Male; Morpholines; Myocardial Reperfusion Injury; Myocardium; Necrosis; Perfusion; Phenanthridines; Phosphatidylinositol 3-Kinases; Platelet Activating Factor; Platelet Aggregation Inhibitors; Protein Kinase C; Rats; Rats, Wistar; Triazoles; Ventricular Function, Left

2005
WEB-2086 and WEB-2170 trigger apoptosis in both ATRA-sensitive and -resistant promyelocytic leukemia cells and greatly enhance ATRA differentiation potential.
    Leukemia, 2005, Volume: 19, Issue:3

    Topics: Antineoplastic Agents; Apoptosis; Azepines; Caspases; Cell Differentiation; Cell Line, Tumor; Dose-Response Relationship, Drug; Drug Resistance, Neoplasm; Humans; Leukemia, Promyelocytic, Acute; Receptors, Retinoic Acid; Tretinoin; Triazoles

2005
The involvement of adhesion molecules and lipid mediators in the adhesion of human platelets to eosinophils.
    Journal of physiology and pharmacology : an official journal of the Polish Physiological Society, 2005, Volume: 56, Issue:4

    Topics: Abciximab; Antibodies, Monoclonal; Aspirin; Azepines; Blood Platelets; Cell Adhesion Molecules; Cyclooxygenase Inhibitors; Eosinophils; Humans; Immunoglobulin Fab Fragments; In Vitro Techniques; Indoles; Inflammation Mediators; L-Selectin; Lipoxygenase Inhibitors; Neutrophils; P-Selectin; Platelet Adhesiveness; Platelet Glycoprotein GPIIb-IIIa Complex; Platelet Membrane Glycoproteins; Polysaccharides; Receptors, G-Protein-Coupled; Thromboxane A2; Triazoles

2005
Lipopolysaccharide induces CXCL2/macrophage inflammatory protein-2 gene expression in enterocytes via NF-kappaB activation: independence from endogenous TNF-alpha and platelet-activating factor.
    Immunology, 2006, Volume: 118, Issue:2

    Topics: Animals; Azepines; Cell Line; Chemokine CXCL2; Chemokines, CXC; Dose-Response Relationship, Immunologic; Electrophoretic Mobility Shift Assay; Enterocytes; Gene Expression Regulation; I-kappa B Proteins; Lipopolysaccharides; NF-kappa B; NF-KappaB Inhibitor alpha; Platelet Activating Factor; Pyrrolidines; Rats; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Transcription, Genetic; Triazoles; Tumor Necrosis Factor-alpha

2006
Phagocytosis of apoptotic and necrotic thymocytes is inhibited by PAF-receptor antagonists and affects LPS-induced COX-2 expression in murine macrophages.
    Prostaglandins & other lipid mediators, 2006, Volume: 80, Issue:1-2

    Topics: Animals; Apoptosis; Azepines; Cyclooxygenase 2; Enzyme Induction; Lipopolysaccharides; Lipoproteins, LDL; Macrophages, Peritoneal; Male; Mice; Mice, Inbred BALB C; Necrosis; Phagocytosis; Phospholipid Ethers; Platelet Membrane Glycoproteins; Receptors, G-Protein-Coupled; T-Lymphocytes; Triazoles

2006
Antiinflammatory and antiallodynic actions of the lignan niranthin isolated from Phyllanthus amarus. Evidence for interaction with platelet activating factor receptor.
    European journal of pharmacology, 2006, Sep-28, Volume: 546, Issue:1-3

    Topics: Analgesics; Animals; Anisoles; Anti-Inflammatory Agents; Azepines; Binding, Competitive; Carrageenan; Cerebral Cortex; Dioxoles; Inflammation; Lignans; Male; Mice; Pain Measurement; Pain Threshold; Peroxidase; Phyllanthus; Plant Extracts; Platelet Activating Factor; Platelet Aggregation Inhibitors; Platelet Membrane Glycoproteins; Pleurisy; Rats; Rats, Wistar; Receptors, G-Protein-Coupled; Tetrahydronaphthalenes; Time Factors; Triazoles

2006
Combined use of WEB2170 and HBO therapy can reduce ischemia and reperfusion injury to the skeletal muscle in a rabbit model.
    Microsurgery, 2007, Volume: 27, Issue:1

    Topics: Animals; Azepines; Combined Modality Therapy; Disease Models, Animal; Hyperbaric Oxygenation; Muscle, Skeletal; Peroxidase; Platelet Aggregation Inhibitors; Rabbits; Reperfusion Injury; Triazoles

2007
Acute pancreatitis affects non-parenchymal liver cells by a mechanism dependent on platelet-activating factor.
    Pancreatology : official journal of the International Association of Pancreatology (IAP) ... [et al.], 2007, Volume: 7, Issue:1

    Topics: Acute Disease; Animals; Azepines; Candida albicans; Kupffer Cells; Lipopolysaccharides; Liver; Male; Nitric Oxide; Pancreatitis; Platelet Activating Factor; Platelet Aggregation Inhibitors; Platelet Membrane Glycoproteins; Rats; Rats, Wistar; Receptors, G-Protein-Coupled; Taurocholic Acid; Triazoles; Tumor Necrosis Factors

2007
Platelet-activating factor stimulates ovine foetal pulmonary vascular smooth muscle cell proliferation: role of nuclear factor-kappa B and cyclin-dependent kinases.
    Cell proliferation, 2008, Volume: 41, Issue:2

    Topics: Animals; Azepines; Cell Proliferation; Cells, Cultured; Cyclin-Dependent Kinases; Dose-Response Relationship, Drug; Female; Flavonoids; Hypoxia; Mitogen-Activated Protein Kinases; Muscle, Smooth, Vascular; NF-kappa B; Oxygen; Platelet Activating Factor; Pulmonary Artery; Pulmonary Veins; Sheep; Structure-Activity Relationship; Triazoles

2008
Mechanistic insight into WEB-2170-induced apoptosis in human acute myelogenous leukemia cells: the crucial role of PTEN.
    Experimental hematology, 2009, Volume: 37, Issue:10

    Topics: Acute Disease; Adult; Aged; Antineoplastic Agents; Apoptosis; Azepines; Cell Line, Tumor; Female; Gene Expression Profiling; Gene Expression Regulation, Leukemic; Humans; Leukemia, Myeloid; Male; Middle Aged; Neoplasm Proteins; Neoplastic Stem Cells; Phosphorylation; Polymerase Chain Reaction; Protein Processing, Post-Translational; Protein Transport; PTEN Phosphohydrolase; Resting Phase, Cell Cycle; RNA Interference; RNA, Small Interfering; Triazoles; Young Adult

2009
Platelet-activating factor receptor (PAF-R)-dependent pathways control tumour growth and tumour response to chemotherapy.
    BMC cancer, 2010, May-13, Volume: 10

    Topics: Animals; Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Azepines; Carcinoma, Ehrlich Tumor; Caspase 3; Cell Proliferation; Cyclooxygenase 2; Dacarbazine; Dinoprostone; Enzyme-Linked Immunosorbent Assay; Female; Flow Cytometry; Galectin 3; Immunohistochemistry; Macrophages; Male; Melanoma, Experimental; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Neovascularization, Pathologic; Nitric Oxide; Phenotype; Platelet Membrane Glycoproteins; Receptors, G-Protein-Coupled; Signal Transduction; Time Factors; Triazoles; Tumor Burden; Vascular Endothelial Growth Factor A

2010
Lipopolysaccharide and platelet-activating factor stimulate expression of platelet-activating factor acetylhydrolase via distinct signaling pathways.
    Inflammation research : official journal of the European Histamine Research Society ... [et al.], 2011, Volume: 60, Issue:8

    Topics: 1-Alkyl-2-acetylglycerophosphocholine Esterase; Azepines; Cell Line; Dose-Response Relationship, Drug; Enzyme Inhibitors; Humans; Imidazoles; Lipopolysaccharides; MAP Kinase Signaling System; p38 Mitogen-Activated Protein Kinases; Platelet Activating Factor; Platelet Membrane Glycoproteins; Pyridines; Receptors, G-Protein-Coupled; RNA, Messenger; Triazoles

2011
Albuterol isomers modulate platelet-activating factor synthesis and receptor signaling in human bronchial smooth muscle cells.
    International archives of allergy and immunology, 2012, Volume: 158, Issue:1

    Topics: Albuterol; Azepines; Bronchi; Bronchodilator Agents; Cell Line; Cell Proliferation; Humans; Inositol 1,4,5-Trisphosphate; Myocytes, Smooth Muscle; Platelet Activating Factor; Platelet Membrane Glycoproteins; Receptors, G-Protein-Coupled; Signal Transduction; Triazoles

2012
Synthesis, biochemical evaluation and molecular modeling studies of novel rhodium complexes with nanomolar activity against Platelet Activating Factor.
    Journal of inorganic biochemistry, 2013, Volume: 120

    Topics: Animals; Azepines; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Inhibitory Concentration 50; Magnetic Resonance Spectroscopy; Models, Molecular; Molecular Dynamics Simulation; Organometallic Compounds; Platelet Activating Factor; Platelet Aggregation Inhibitors; Rabbits; Rhodium; Structure-Activity Relationship; Thrombin; Triazoles

2013
Activation of platelet-activating factor receptor exacerbates renal inflammation and promotes fibrosis.
    Laboratory investigation; a journal of technical methods and pathology, 2014, Volume: 94, Issue:4

    Topics: Animals; Azepines; Collagen; Disease Models, Animal; Fibrosis; Kidney; Mice; Mice, Inbred BALB C; Mice, Knockout; Nephritis; Platelet Membrane Glycoproteins; Receptors, G-Protein-Coupled; Renal Insufficiency, Chronic; Triazoles; Ureteral Obstruction

2014
Boosting Adaptive Immunity: A New Role for PAFR Antagonists.
    Scientific reports, 2016, 12-14, Volume: 6

    Topics: Adaptive Immunity; Animals; Azepines; CD4-Positive T-Lymphocytes; Cells, Cultured; Dendritic Cells; Freund's Adjuvant; Immunization; Immunoglobulin G; Mice; Ovalbumin; Platelet Aggregation Inhibitors; Platelet Membrane Glycoproteins; Receptors, G-Protein-Coupled; Spleen; Triazoles

2016