triazoles has been researched along with azd2066 in 6 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 6 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Astrand, M; Boeckxstaens, GE; Hansen, MB; Hirsch, DP; Lei, A; Ny, L; Rohof, WO | 1 |
| Cselényi, Z; Halldin, C; Hooker, AC; Kågedal, M; Karlsson, MO; Nyberg, S; Raboisson, P; Ståhle, L; Stenkrona, P; Varnäs, K | 1 |
| Andersson, A; Baranczewski, P; Nordmark, A; Ståhle, L; Wanag, E | 1 |
| Raboisson, P; Swedberg, MD | 1 |
| Ang, D; De Santis, A; Pauwels, A; Scarpellini, E; Tack, J; Vanuytsel, T | 1 |
| Harmon, SK; Jong, YI; O'Malley, KL | 1 |
1 review(s) available for triazoles and azd2066
| Article | Year |
|---|---|
Management of refractory typical GERD symptoms.
Topics: Alginates; Algorithms; Antacids; Baclofen; Chronic Disease; Esophagoscopy; Gastroesophageal Reflux; Gastrointestinal Agents; Gastroscopy; Humans; Isoxazoles; Muscle Relaxants, Central; Neurotransmitter Agents; Phosphinic Acids; Propylamines; Triazoles | 2016 |
3 trial(s) available for triazoles and azd2066
| Article | Year |
|---|---|
The effects of a novel metabotropic glutamate receptor 5 antagonist (AZD2066) on transient lower oesophageal sphincter relaxations and reflux episodes in healthy volunteers.
Topics: Adult; Analysis of Variance; Cross-Over Studies; Dose-Response Relationship, Drug; Double-Blind Method; Esophageal Sphincter, Lower; Gastroesophageal Reflux; Gastrointestinal Agents; Humans; Hydrogen-Ion Concentration; Isoxazoles; Male; Postprandial Period; Receptor, Metabotropic Glutamate 5; Receptors, Metabotropic Glutamate; Triazoles; Young Adult | 2012 |
A positron emission tomography study in healthy volunteers to estimate mGluR5 receptor occupancy of AZD2066 - estimating occupancy in the absence of a reference region.
Topics: Adult; Analgesics; Anti-Anxiety Agents; Brain; Carbon Radioisotopes; Healthy Volunteers; Humans; Isoxazoles; Male; Middle Aged; Oximes; Positron-Emission Tomography; Pyridines; Radiopharmaceuticals; Receptor, Metabotropic Glutamate 5; Triazoles; Young Adult | 2013 |
Assessment of interaction potential of AZD2066 using in vitro metabolism tools, physiologically based pharmacokinetic modelling and in vivo cocktail data.
Topics: Adult; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Drug Interactions; Humans; Isoxazoles; Male; Microsomes, Liver; Middle Aged; Models, Biological; Receptor, Metabotropic Glutamate 5; Triazoles; Young Adult | 2014 |
2 other study(ies) available for triazoles and azd2066
| Article | Year |
|---|---|
AZD9272 and AZD2066: selective and highly central nervous system penetrant mGluR5 antagonists characterized by their discriminative effects.
Topics: Animals; Discrimination Learning; Dose-Response Relationship, Drug; Dronabinol; Isoxazoles; Male; Oxadiazoles; Pyridines; Rats; Rats, Wistar; Receptor, Metabotropic Glutamate 5; Thiazoles; Triazoles | 2014 |
Location and Cell-Type-Specific Bias of Metabotropic Glutamate Receptor, mGlu
Topics: Allosteric Regulation; Animals; Animals, Newborn; Brain; Cells, Cultured; HEK293 Cells; Humans; Indoles; Isoxazoles; Rats; Receptor, Metabotropic Glutamate 5; Triazoles | 2019 |