Page last updated: 2024-08-24

triazoles and azamulin

triazoles has been researched along with azamulin in 7 studies

Research

Studies (7)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's3 (42.86)29.6817
2010's2 (28.57)24.3611
2020's2 (28.57)2.80

Authors

AuthorsStudies
Blanchard, AP; Broudy, MI; Cargill, CE; Crespi, CL; Dandeneau, AA; Dehal, SS; Erve, JC; Goodwin, JJ; Ho, T; Patten, CJ; Sharma, R; Stresser, DM; Turner, SD1
Enomoto, M; Matsui, H; Ohhira, S1
Alton, KB; Chowdhury, SK; Ghosal, A; Hapangama, N; Kishnani, NS; Ramanathan, R; Yuan, Y1
Goodman, OB; Mitra, R1
Sevrioukova, IF1
Chanteux, H; Delatour, C; Dell'Aiera, S; Gillent, E; Nicolaï, J; Rosa, M; Ungell, AL1
Hsu, MH; Johnson, EF1

Other Studies

7 other study(ies) available for triazoles and azamulin

ArticleYear
Highly selective inhibition of human CYP3Aa in vitro by azamulin and evidence that inhibition is irreversible.
    Drug metabolism and disposition: the biological fate of chemicals, 2004, Volume: 32, Issue:1

    Topics: Anti-Infective Agents; Bridged-Ring Compounds; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Enzyme Inhibitors; Fluorometry; Humans; In Vitro Techniques; Ketoconazole; Microsomes, Liver; NADP; Pleurotus; Solubility; Steroid Hydroxylases; Substrate Specificity; Triazoles; Xenobiotics

2004
In vitro metabolism of tributyltin and triphenyltin by human cytochrome P-450 isoforms.
    Toxicology, 2006, Dec-07, Volume: 228, Issue:2-3

    Topics: Biotransformation; Bridged-Ring Compounds; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; DNA, Complementary; Enzyme Inhibitors; Female; Humans; Isoenzymes; Liver; Male; Mephenytoin; Microsomes, Liver; Organotin Compounds; Recombinant Proteins; Trialkyltin Compounds; Triazoles

2006
Identification of human liver cytochrome P450 enzymes involved in biotransformation of vicriviroc, a CCR5 receptor antagonist.
    Drug metabolism and disposition: the biological fate of chemicals, 2007, Volume: 35, Issue:12

    Topics: Antibodies, Monoclonal; Aryl Hydrocarbon Hydroxylases; Biotransformation; Bridged-Ring Compounds; Carboxylic Acids; CCR5 Receptor Antagonists; Cytochrome P-450 CYP2C9; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Dealkylation; Enzyme Inhibitors; Humans; Immunologic Factors; In Vitro Techniques; Isoenzymes; Ketoconazole; Kinetics; Liver; Oxidation-Reduction; Piperazines; Pyrimidines; Recombinant Proteins; Substrate Specificity; Testosterone; Triazoles

2007
CYP3A5 regulates prostate cancer cell growth by facilitating nuclear translocation of AR.
    The Prostate, 2015, Apr-01, Volume: 75, Issue:5

    Topics: Blotting, Western; Bridged-Ring Compounds; Cell Line, Tumor; Cytochrome P-450 CYP3A; Cytochrome P-450 CYP3A Inhibitors; Dihydrotestosterone; Fluorescent Antibody Technique; Humans; Male; Metribolone; Prostatic Neoplasms; Real-Time Polymerase Chain Reaction; Receptors, Androgen; RNA, Small Interfering; Signal Transduction; Triazoles

2015
Structural Insights into the Interaction of Cytochrome P450 3A4 with Suicide Substrates: Mibefradil, Azamulin and 6',7'-Dihydroxybergamottin.
    International journal of molecular sciences, 2019, Aug-30, Volume: 20, Issue:17

    Topics: Bridged-Ring Compounds; Crystallography, X-Ray; Cytochrome P-450 CYP3A; Furocoumarins; Humans; Mibefradil; Models, Molecular; Substrate Specificity; Triazoles

2019
Application of Azamulin to Determine the Contribution of CYP3A4/5 to Drug Metabolic Clearance Using Human Hepatocytes.
    Drug metabolism and disposition: the biological fate of chemicals, 2020, Volume: 48, Issue:9

    Topics: Bridged-Ring Compounds; Cells, Cultured; Cytochrome P-450 CYP3A; Cytochrome P-450 CYP3A Inhibitors; Drug Evaluation, Preclinical; Drug Interactions; Hepatobiliary Elimination; Hepatocytes; Humans; Liver; Microsomes, Liver; Primary Cell Culture; Triazoles

2020
Structural characterization of the homotropic cooperative binding of azamulin to human cytochrome P450 3A5.
    The Journal of biological chemistry, 2022, Volume: 298, Issue:5

    Topics: Bridged-Ring Compounds; Catalytic Domain; Cytochrome P-450 CYP3A; Humans; Triazoles

2022