Page last updated: 2024-08-24

triazoles and alpha-aminopyridine

triazoles has been researched along with alpha-aminopyridine in 38 studies

Research

Studies (38)

Timeframe	Studies, this research(%)	All Research%
pre-1990	1 (2.63)	18.7374
1990's	0 (0.00)	18.2507
2000's	3 (7.89)	29.6817
2010's	28 (73.68)	24.3611
2020's	6 (15.79)	2.80

Authors

Authors	Studies
ANAND, N; CHATTERJEE, SK; JAIN, PC; PRADHAN, SN; VOHRA, MM	1
Kumar, JS; Majo, VJ; Mann, JJ; Parsey, RV; Prabhakaran, J; Simpson, NR; Sullivan, GM; Van Heertum, RL	1
Church, JE; Coupar, IM; Pouton, CW; Rose'Meyer, RB; Urmaliya, VB; White, PJ	1
Krahn, T; Ledent, C; Mustafa, SJ; Ponnoth, DS; Roush, K; Sanjani, MS	1
Beukers, MW; Guo, D; Ijzerman, AP; Müller, CE; Peeters, MC; van Westen, GJ; Wisse, LE	1
Abe, S; Asada, M; Hata, K; Horii, T; Inoue, S; Matsukura, M; Miyazaki, M; Murai, N; Nakamoto, K; Shirotori, S; Tanaka, K; Watanabe, NA; Yoshimatsu, K	1
Castanheira, M; Duncanson, F; Jones, RN; Messer, SA; Moet, GJ; Pfaller, MA	1
Castanheira, M; Diekema, DJ; Duncanson, FP; Guarro, J; Jones, RN; Pfaller, MA	1
Arrowsmith, J; Drummond, KS; Feltner, DE; Morgan, P; Street, SD; Van Der Graaf, PH; Wegner, CD	1
Armstrong, JL; Brancale, A; Bridgens, CE; Gomaa, MS; Illingworth, NA; Lau, SC; Lim, AS; Redfern, CP; Simons, C; Veal, GJ; Watts, AM	1
Abramson, VG; Arteaga, CL; Balko, JM; Cantley, LC; Forero, A; Isakoff, SJ; Kuba, MG; Li, Y; Mayer, IA; Sanders, ME; Van den Abbeele, AD; Winer, E; Yap, JT	1
Delibašić, G; Hrustić, J; Mihajlović, M; Mirković, B; Stević, M; Tanović, B; Vukša, P	1
Hattori, T; Nahata, M; Nakagawa, K; Ohnishi, S; Okubo, N; Sadakane, C; Saegusa, Y; Takeda, H; Yamada, C	1
Cock, I; de Koning, CB; Giri, S; Leboho, TC; Michael, JP; Popova, I	1
Bittner, T; Fischer-Iglesias, C; Nadler, S; Schulze, E	1
Bardia, A; Beck, JT; Conte, P; Curigliano, G; Dhuria, S; Di Tomaso, E; Gómez Pardo, P; Hurvitz, SA; Lolkema, MP; Martínez García, M; Meric-Bernstam, F; Miller, M; Penault-Llorca, F; Solovieff, N; Tang, Z	1
Alba, E; André, F; Arteaga, CL; Bachelot, T; Blackwell, KL; Blau, S; Burdaeva, O; Burris, HA; Cameron, DA; Campone, M; Chan, A; Conte, P; Favret, AM; Germa, C; Grischke, EM; Hart, LL; Hirawat, S; Hortobagyi, GN; Jakobsen, E; Janni, W; Marschner, N; Miller, M; Nusch, A; O'Shaughnessy, J; Paluch-Shimon, S; Petrakova, K; Sonke, GS; Souami, F; Stemmer, SM; Tseng, LM; Verma, S; Villanueva, C; Winer, EP; Wist, E; Xuan, F; Yap, YS; Yardley, D	1
Akıncı, MB; Bilgin, B; Sendur, MAN; Şener Dede, D; Yalçın, B	1
Messina, C; Messina, M; Zanardi, E	1
Barriga, S; Bourayou, N; Campone, M; Chen, SC; Di Leo, A; Forrester, T; Freedman, OC; Frenzel, M; Garnica Jaliffe, G; Goetz, MP; Huober, J; Manso, L; Paluch-Shimon, S; Park, IH; Smith, IC; Sohn, J; Toi, M; Trédan, O	1
Alba, E; Bachelot, T; Burris, HA; Campone, M; Erdkamp, F; Favret, AM; Germa, C; Hart, LL; Hegg, R; Jakobsen, E; Janni, W; Miller, M; Sonke, GS; Souami, F; Sutradhar, S; Verma, S; Villanueva, C; Wheatley-Price, P; Wist, E	1
Bhattacharyya, D; Bhattacharyya, S; Biskupiak, J; Brixner, D; Dalal, AA; May, JR; Mishra, D; Mistry, R; Oderda, G; Suri, G; Tang, D; Young, K	1
Huang, P; Liu, X; Wu, H; Zhang, F	1
Chen, Z; Han, J; Miao, G; Ye, T; Zhang, K	1
Covel, J; Fierer, J; Kapoor, M; Okamoto, S; Shaw, KJ; Soltow, QA; Trzoss, M; Viriyakosol, S	1
Babu, KS; Baig, MF; Kamal, A; Lakshma Nayak, V; Prasad, B; Srikanth, PS; Subba Reddy, NV	1
Huang, P; Li, Q; Liu, X; Tong, D; Wu, H; Zhang, F	1
Dai, Y; Gao, T; Geng, J; Hu, J; Lamour, K; Liu, X; Ren, H; Zhou, Y	1
Baldelli, S; Cattaneo, D; Clementi, E; Colombo, C; Cozzi, V; Faelli, NML; Fusi, M; Russo, M	1
Estey, EH; Percival, MM	1
Akakpo, S; Chalon, S; Chughlay, MF; Csermak-Renner, K; Djeriou, E; Gaur, AH; Leboulleux, D; McCarthy, J; Odedra, A; Shanks, GD; Winnips, C	1
Aller, SG; Bacsa, J; Breton, GW; Doiron, JE; Le, CA; Martin, KL; Turlington, M	1
Adderley, T; Christopher, G; Irwin, MS; Kano, Y; Kee, L; Ladumor, Y; Ohh, M; Robinson, CM; Valencia-Sama, I	1
Armacost, KA; Breslin, MJ; Brooun, A; Byrne, NJ; Hall, DL; Hollenstein, K; Hollingsworth, SA; Hong, C; Kern, JC; McDonald, TP; Minnick, C; O'Brien, JA; Partridge, AT; Rada, VL; Rudd, MT; Shipman, JM; Soisson, SM; Stachel, SJ; Strickland, C; Tummala, S; Xiao, L; Zamlynny, B	1
Aguiar, JA; Ask, K; Cao, Q; Doxey, AC; Hirota, JA; Hou, V; Huff, RD; Inman, MD; Kim, Y; Miller, MS; Revill, S; Tiessen, N	1
Amaral, MD; Bacalhau, M; Buarque, CD; da Silva, VD; Ferreira, FC; Kmit, A; Lopes-Pacheco, M; Pimentel, AS; Souza, FR	1

Reviews

3 review(s) available for triazoles and alpha-aminopyridine

Article	Year
A current and comprehensive review of cyclin-dependent kinase inhibitors for the treatment of metastatic breast cancer. Current medical research and opinion, 2017, Volume: 33, Issue:9 Topics: Aminopyridines; Antineoplastic Combined Chemotherapy Protocols; Benzimidazoles; Breast Neoplasms; Cyclin-Dependent Kinase 4; Disease-Free Survival; Estradiol; Female; Fulvestrant; Humans; Letrozole; Nitriles; Piperazines; Protein Kinase Inhibitors; Purines; Pyridines; Randomized Controlled Trials as Topic; Triazoles	2017
Risks and benefits from CDK inhibitors for advanced HR+ Her 2- breast cancer. Annals of oncology : official journal of the European Society for Medical Oncology, 2017, 12-01, Volume: 28, Issue:12 Topics: Aminopyridines; Antineoplastic Combined Chemotherapy Protocols; Benzimidazoles; Breast Neoplasms; Cyclin-Dependent Kinases; Estradiol; Female; Fulvestrant; Humans; Letrozole; Nitriles; Piperazines; Protein Kinase Inhibitors; Purines; Pyridines; Randomized Controlled Trials as Topic; Receptor, ErbB-2; Receptors, Estrogen; Risk Assessment; Triazoles	2017
Current treatment strategies for measurable residual disease in patients with acute myeloid leukemia. Cancer, 2019, Sep-15, Volume: 125, Issue:18 Topics: Aminopyridines; Aniline Compounds; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antineoplastic Agents; Antineoplastic Agents, Immunological; Azacitidine; Cytogenetic Analysis; Decitabine; Enzyme Inhibitors; Flow Cytometry; Hematopoietic Stem Cell Transplantation; Humans; Hydrazines; Immunologic Factors; In Situ Hybridization, Fluorescence; Lenalidomide; Leukemia, Myeloid, Acute; Molecular Diagnostic Techniques; Neoplasm, Residual; Nivolumab; para-Aminobenzoates; Protein Kinase Inhibitors; Pyrazines; Pyrrolidines; Recombinant Fusion Proteins; Remission Induction; Transplantation, Homologous; Triazines; Triazoles	2019

Trials

5 trial(s) available for triazoles and alpha-aminopyridine

Article	Year
Stand up to cancer phase Ib study of pan-phosphoinositide-3-kinase inhibitor buparlisib with letrozole in estrogen receptor-positive/human epidermal growth factor receptor 2-negative metastatic breast cancer. Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2014, Apr-20, Volume: 32, Issue:12 Topics: Adult; Aged; Aminopyridines; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Cell Line, Tumor; Class I Phosphatidylinositol 3-Kinases; Dose-Response Relationship, Drug; Drug Administration Schedule; Female; Fluorodeoxyglucose F18; Humans; Letrozole; Middle Aged; Morpholines; Multimodal Imaging; Nitriles; Phosphoinositide-3 Kinase Inhibitors; Positron-Emission Tomography; Protein Kinase Inhibitors; Radiopharmaceuticals; Receptor, ErbB-2; Receptors, Estrogen; Tomography, X-Ray Computed; Triazoles	2014
Ribociclib plus letrozole in early breast cancer: A presurgical, window-of-opportunity study. Breast (Edinburgh, Scotland), 2016, Volume: 28 Topics: Aged; Aminopyridines; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Cyclin D2; Cyclin D3; Cyclin E; Cyclin-Dependent Kinase 4; Cyclin-Dependent Kinase 6; DNA, Neoplasm; Female; Gene Expression; Humans; Ki-67 Antigen; Letrozole; Middle Aged; Neoadjuvant Therapy; Nitriles; Oncogene Proteins; Purines; Receptor, ErbB-2; Receptors, Estrogen; Receptors, Progesterone; Retinoblastoma Protein; Signal Transduction; Triazoles	2016
Ribociclib as First-Line Therapy for HR-Positive, Advanced Breast Cancer. The New England journal of medicine, 2016, 11-03, Volume: 375, Issue:18 Topics: Adult; Aged; Aged, 80 and over; Aminopyridines; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Disease-Free Survival; Double-Blind Method; Drug Administration Schedule; Female; Humans; Kaplan-Meier Estimate; Letrozole; Middle Aged; Neoplasm Staging; Nitriles; Purines; Receptor, ErbB-2; Receptors, Estrogen; Receptors, Progesterone; Triazoles	2016
MONARCH 3: Abemaciclib As Initial Therapy for Advanced Breast Cancer. Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2017, Nov-10, Volume: 35, Issue:32 Topics: Adult; Aged; Aged, 80 and over; Aminopyridines; Anastrozole; Antineoplastic Combined Chemotherapy Protocols; Aromatase Inhibitors; Benzimidazoles; Biomarkers, Tumor; Breast Neoplasms; Double-Blind Method; Female; Humans; Letrozole; Middle Aged; Nitriles; Postmenopause; Receptor, ErbB-2; Survival Rate; Treatment Outcome; Triazoles	2017
Ribociclib with letrozole vs letrozole alone in elderly patients with hormone receptor-positive, HER2-negative breast cancer in the randomized MONALEESA-2 trial. Breast cancer research and treatment, 2018, Volume: 167, Issue:3 Topics: Aged; Aged, 80 and over; Aminopyridines; Antineoplastic Combined Chemotherapy Protocols; Biomarkers, Tumor; Breast Neoplasms; Disease-Free Survival; Female; Humans; Letrozole; Middle Aged; Nitriles; Purines; Receptor, ErbB-2; Receptors, Estrogen; Receptors, Progesterone; Triazoles	2018

Other Studies

30 other study(ies) available for triazoles and alpha-aminopyridine

Article	Year
SYNTHESIS AND STRUCTURE-ACTIVITY RELATIONSHIPS OF SOME AMINOPYRIDINES, IMIDAZOPYRIDINES, AND TRIAZOLOPYRIDINES. Journal of medicinal chemistry, 1965, Volume: 8 Topics: Aminopyridines; Barbiturates; Cardiovascular System; Chemistry, Pharmaceutical; Imidazoles; Mice; Pharmacology; Pyridines; Research; Structure-Activity Relationship; Toxicology; Triazoles	1965
Synthesis and in vivo evaluation of [11C]SN003 as a PET ligand for CRF1 receptors. Bioorganic & medicinal chemistry, 2006, Jun-15, Volume: 14, Issue:12 Topics: Aminopyridines; Animals; Carbon Radioisotopes; Isotope Labeling; Ligands; Molecular Structure; Papio; Positron-Emission Tomography; Pyridines; Receptors, Corticotropin-Releasing Hormone; Time Factors; Triazoles	2006
Cardioprotection induced by adenosine A1 receptor agonists in a cardiac cell ischemia model involves cooperative activation of adenosine A2A and A2B receptors by endogenous adenosine. Journal of cardiovascular pharmacology, 2009, Volume: 53, Issue:5 Topics: Acetamides; Adenosine; Adenosine A1 Receptor Agonists; Adenosine A2 Receptor Agonists; Adenosine A2 Receptor Antagonists; Adenosine A3 Receptor Agonists; Adenosine A3 Receptor Antagonists; Aminopyridines; Animals; Apoptosis; Cardiotonic Agents; Cell Line; Cell Survival; Dihydropyridines; Imidazoles; Myocardial Ischemia; Phenethylamines; Purines; Rats; Triazines; Triazoles; Xanthines	2009
Absence of adenosine-mediated aortic relaxation in A(2A) adenosine receptor knockout mice. American journal of physiology. Heart and circulatory physiology, 2009, Volume: 297, Issue:5 Topics: Acetylcholine; Adenosine; Adenosine-5'-(N-ethylcarboxamide); Aminopyridines; Animals; Aorta; Dose-Response Relationship, Drug; Endothelium, Vascular; Female; Flavins; Gene Expression Regulation; In Vitro Techniques; Male; Mice; Mice, Knockout; Phenethylamines; Pyrimidines; Receptor, Adenosine A1; Receptor, Adenosine A2A; Receptor, Adenosine A2B; Triazoles; Vasoconstriction; Vasoconstrictor Agents; Vasodilation; Vasodilator Agents; Xanthines	2009
GPCR structure and activation: an essential role for the first extracellular loop in activating the adenosine A2B receptor. FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 2011, Volume: 25, Issue:2 Topics: Adenosine A2 Receptor Agonists; Adenosine A2 Receptor Antagonists; Adenosine-5'-(N-ethylcarboxamide); Amino Acid Sequence; Aminopyridines; Gene Expression Regulation; Humans; Models, Molecular; Molecular Structure; Mutagenesis, Site-Directed; Protein Conformation; Receptor, Adenosine A2B; Saccharomyces cerevisiae; Triazines; Triazoles	2011
In vitro activity of E1210, a novel antifungal, against clinically important yeasts and molds. Antimicrobial agents and chemotherapy, 2011, Volume: 55, Issue:10 Topics: Aminopyridines; Amphotericin B; Antifungal Agents; Aspergillus; Candida; Cell Line; Echinocandins; Fluconazole; Fungi; Fusarium; Humans; Isoxazoles; Itraconazole; Lipopeptides; Micafungin; Microbial Sensitivity Tests; Paecilomyces; Pseudallescheria; Pyrimidines; Scedosporium; Triazoles; Voriconazole; Yeasts	2011
In vitro activity of a novel broad-spectrum antifungal, E1210, tested against Aspergillus spp. determined by CLSI and EUCAST broth microdilution methods. Antimicrobial agents and chemotherapy, 2011, Volume: 55, Issue:11 Topics: Aminopyridines; Anidulafungin; Antifungal Agents; Aspergillus; Aspergillus flavus; Aspergillus fumigatus; Caspofungin; Echinocandins; Isoxazoles; Itraconazole; Lipopeptides; Microbial Sensitivity Tests; Pyrimidines; Triazoles; Voriconazole	2011
Activities of E1210 and comparator agents tested by CLSI and EUCAST broth microdilution methods against Fusarium and Scedosporium species identified using molecular methods. Antimicrobial agents and chemotherapy, 2012, Volume: 56, Issue:1 Topics: Acylation; Aminopyridines; Amphotericin B; Anidulafungin; Antifungal Agents; Caspofungin; Echinocandins; Fusarium; Glycosylphosphatidylinositols; Humans; Inositol; Isoxazoles; Itraconazole; Lipopeptides; Microbial Sensitivity Tests; Pyrimidines; Scedosporium; Triazoles; Voriconazole	2012
Can the flow of medicines be improved? Fundamental pharmacokinetic and pharmacological principles toward improving Phase II survival. Drug discovery today, 2012, Volume: 17, Issue:9-10 Topics: Aminopyridines; Animals; CCR5 Receptor Antagonists; Clinical Trials, Phase II as Topic; Cyclohexanes; Drug Evaluation; HIV Infections; Humans; Maraviroc; Morpholines; Neuralgia; Pharmaceutical Preparations; Pharmacokinetics; Receptors, Dopamine D3; Sexual Dysfunction, Physiological; Triazoles	2012
Synthesis and CYP26A1 inhibitory activity of novel methyl 3-[4-(arylamino)phenyl]-3-(azole)-2,2-dimethylpropanoates. Bioorganic & medicinal chemistry, 2012, Oct-15, Volume: 20, Issue:20 Topics: Aminopyridines; Azoles; Binding Sites; Catalytic Domain; Cell Survival; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Humans; Imidazoles; MCF-7 Cells; Microsomes; Molecular Docking Simulation; Phenylpropionates; Propionates; Retinoic Acid 4-Hydroxylase; Structure-Activity Relationship; Tretinoin; Triazoles	2012
Toxicity of copper hydroxide, dithianon, fluazinam, tebuconazole and pyraclostrobin to Didymella applanata isolates from Serbia. Journal of environmental science and health. Part. B, Pesticides, food contaminants, and agricultural wastes, 2015, Volume: 50, Issue:3 Topics: Aminopyridines; Anthraquinones; Ascomycota; Carbamates; Copper; Fungicides, Industrial; Hydroxides; Microbial Sensitivity Tests; Plant Diseases; Pyrazoles; Rubus; Serbia; Strobilurins; Triazoles	2015
Serotonin 2C receptor contributes to gender differences in stress-induced hypophagia in aged mice. Psychoneuroendocrinology, 2015, Volume: 55 Topics: Age Factors; Aminopyridines; Animals; Anorexia; Aromatase Inhibitors; Brain; Corticosterone; ERRalpha Estrogen-Related Receptor; Feeding Behavior; Female; Ghrelin; Indoles; Letrozole; Male; Mice; Nitriles; Paraventricular Hypothalamic Nucleus; Phenols; Piperazines; Pyrazines; Pyrazoles; Receptor, Serotonin, 5-HT2C; Receptors, Estrogen; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Serotonin 5-HT2 Receptor Agonists; Serotonin 5-HT2 Receptor Antagonists; Sex Factors; Stress, Psychological; Triazoles	2015
Double Sonogashira reactions on dihalogenated aminopyridines for the assembly of an array of 7-azaindoles bearing triazole and quinoxaline substituents at C-5: Inhibitory bioactivity against Giardia duodenalis trophozoites. Bioorganic & medicinal chemistry, 2015, Aug-01, Volume: 23, Issue:15 Topics: Aminopyridines; Antiparasitic Agents; Aza Compounds; Giardia lamblia; Halogenation; Indoles; Quinoxalines; Structure-Activity Relationship; Triazoles; Trophozoites	2015
Two homolog wheat Glycogen Synthase Kinase 3/SHAGGY--like kinases are involved in brassinosteroid signaling. BMC plant biology, 2015, Oct-13, Volume: 15 Topics: Aminopyridines; Arabidopsis; Arabidopsis Proteins; Brassinosteroids; Gene Expression Regulation, Plant; Glycogen Synthase Kinase 3; Mutation; Phenotype; Plant Proteins; Plants, Genetically Modified; Seedlings; Sequence Homology, Amino Acid; Signal Transduction; Succinates; Triazoles; Triticum	2015
Ribociclib Lengthens Breast Cancer Survival. Cancer discovery, 2016, Volume: 6, Issue:12 Topics: Aminopyridines; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Clinical Trials as Topic; Disease-Free Survival; Female; Humans; Letrozole; Nitriles; Purines; Treatment Outcome; Triazoles	2016
Abemaciclib Shows Promise for Early Breast Cancer. Cancer discovery, 2017, Volume: 7, Issue:2 Topics: Aminopyridines; Anastrozole; Antineoplastic Agents; Antineoplastic Agents, Hormonal; Antineoplastic Combined Chemotherapy Protocols; Benzimidazoles; Breast Neoplasms; Clinical Trials, Phase II as Topic; Disease-Free Survival; Female; Humans; Ki-67 Antigen; Nitriles; Receptor, ErbB-2; Survival Analysis; Treatment Outcome; Triazoles	2017
Cost-Effectiveness of Ribociclib plus Letrozole Versus Palbociclib plus Letrozole and Letrozole Monotherapy in the First-Line Treatment of Postmenopausal Women with HR+/HER2- Advanced or Metastatic Breast Cancer: A U.S. Payer Perspective. Journal of managed care & specialty pharmacy, 2018, Volume: 24, Issue:6 Topics: Aminopyridines; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Cost-Benefit Analysis; Disease-Free Survival; Female; Humans; Letrozole; Models, Biological; Models, Economic; Nitriles; Piperazines; Postmenopause; Protein Kinase Inhibitors; Purines; Pyridines; Receptor, ErbB-2; Receptors, Estrogen; Receptors, Progesterone; Survival Analysis; Treatment Outcome; Triazoles; United States	2018
JQ1 and PI3K inhibition synergistically reduce salivary adenoid cystic carcinoma malignancy by targeting the c-Myc and EGFR signaling pathways. Journal of oral pathology & medicine : official publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology, 2019, Volume: 48, Issue:1 Topics: Aminopyridines; Apoptosis; Azepines; Carcinoma, Adenoid Cystic; Cell Cycle Proteins; Cell Proliferation; Cell Survival; Drug Synergism; Drug Therapy, Combination; ErbB Receptors; Gene Expression; Humans; Molecular Targeted Therapy; Morpholines; Nuclear Proteins; Phosphoinositide-3 Kinase Inhibitors; Proto-Oncogene Proteins c-myc; Salivary Gland Neoplasms; Signal Transduction; Transcription Factors; Triazoles; Tumor Cells, Cultured	2019
Efficiency and Safety Assurance of Six Fungicides Applied on Postharvest Cabbages Stored in a Natural Environment. Journal of agricultural and food chemistry, 2018, Oct-17, Volume: 66, Issue:41 Topics: Aminopyridines; Benzimidazoles; Biodegradation, Environmental; Botrytis; Brassica; Carbamates; Consumer Product Safety; Food Preservation; Fungicides, Industrial; Half-Life; Humans; Kinetics; Nitriles; Pesticide Residues; Plant Leaves; Pyrimidines; Strobilurins; Triazoles	2018
APX001 and Other Gwt1 Inhibitor Prodrugs Are Effective in Experimental Antimicrobial agents and chemotherapy, 2019, Volume: 63, Issue:2 Topics: Aminopyridines; Amphotericin B; Animals; Antifungal Agents; Coccidioides; Disease Models, Animal; Female; Fluconazole; Isoxazoles; Mice; Mice, Inbred C57BL; Microbial Sensitivity Tests; Pneumonia; Prodrugs; Triazoles	2019
Synthesis and biological evaluation of 1-benzyl-N-(2-(phenylamino)pyridin-3-yl)-1H-1,2,3-triazole-4-carboxamides as antimitotic agents. Bioorganic chemistry, 2019, Volume: 83 Topics: Aminopyridines; Animals; Antimitotic Agents; Apoptosis; Cell Line, Tumor; Cell Proliferation; Drug Design; Drug Screening Assays, Antitumor; G2 Phase Cell Cycle Checkpoints; Humans; Membrane Potential, Mitochondrial; Molecular Docking Simulation; Molecular Structure; Polymerization; Protein Binding; Rats; Sheep, Domestic; Structure-Activity Relationship; Triazoles; Tubulin; Tubulin Modulators	2019
EGFR-mediated signaling pathway influences the sensitivity of oral squamous cell carcinoma to JQ1. Journal of cellular biochemistry, 2018, Volume: 119, Issue:10 Topics: Aminopyridines; Analysis of Variance; Animals; Antineoplastic Agents; Apoptosis; Azepines; Biomarkers, Tumor; Carcinoma, Squamous Cell; Cell Cycle Proteins; Cell Line, Tumor; Cell Proliferation; Drug Synergism; Epidermal Growth Factor; ErbB Receptors; Female; Gene Knockdown Techniques; Humans; Mice; Morpholines; Mouth Neoplasms; Nuclear Proteins; Phosphoinositide-3 Kinase Inhibitors; Signal Transduction; Transcription Factors; Triazoles; Xenograft Model Antitumor Assays	2018
Resistance risk assessment for fludioxonil in Sclerotinia homoeocarpa in China. Pesticide biochemistry and physiology, 2019, Volume: 156 Topics: Aminoimidazole Carboxamide; Aminopyridines; Ascomycota; China; Dioxoles; Drug Resistance, Fungal; Fungal Proteins; Fungicides, Industrial; Gene Expression Regulation, Fungal; Hydantoins; Mutation; Pyrroles; Thiophanate; Triazoles	2019
Unexpected analytical interference in isavuconazole UV determination in a child in therapy with lumacaftor/ivacaftor for cystic fibrosis. Clinical chemistry and laboratory medicine, 2019, Oct-25, Volume: 57, Issue:11 Topics: Aminophenols; Aminopyridines; Antifungal Agents; Antineoplastic Combined Chemotherapy Protocols; Benzodioxoles; Cystic Fibrosis; Female; Humans; Male; Nitriles; Pyridines; Quinolones; Triazoles	2019
Liver Enzyme Elevations in The American journal of tropical medicine and hygiene, 2020, Volume: 103, Issue:1 Topics: Acrylamides; Adamantane; Adult; Alanine Transaminase; Aminopyridines; Aminoquinolines; Antimalarials; Aspartate Aminotransferases; Chemical and Drug Induced Liver Injury; Erythrocyte Transfusion; Erythrocytes; Female; Ferrous Compounds; Healthy Volunteers; Heterocyclic Compounds, 4 or More Rings; Humans; Indoles; Isoquinolines; Malaria, Falciparum; Male; Metallocenes; Parasitemia; Peroxides; Piperazines; Plasmodium falciparum; Primaquine; Pyrimidines; Quinolines; Spiro Compounds; Sulfones; Triazoles; Young Adult	2020
Structural Consequences of the 1,2,3-Triazole as an Amide Bioisostere in Analogues of the Cystic Fibrosis Drugs VX-809 and VX-770. ChemMedChem, 2020, 09-16, Volume: 15, Issue:18 Topics: Amides; Aminophenols; Aminopyridines; Benzodioxoles; Crystallography, X-Ray; Cystic Fibrosis; Humans; Models, Molecular; Molecular Structure; Quantum Theory; Quinolones; Triazoles	2020
Cancer research, 2020, 08-15, Volume: 80, Issue:16 Topics: Aminopyridines; Animals; Antineoplastic Agents; Cell Line, Tumor; Drug Resistance, Neoplasm; Drug Synergism; Genes, ras; Heterografts; Humans; Indoles; Male; MAP Kinase Signaling System; Mice, Inbred NOD; Mice, SCID; Mitogen-Activated Protein Kinase Kinases; Mutation; Neoplasm Recurrence, Local; Neuroblastoma; Piperidines; Protein Tyrosine Phosphatase, Non-Receptor Type 11; Pyridones; Pyrimidines; Pyrimidinones; Pyrroles; Triazoles; Vemurafenib	2020
Structures of active-state orexin receptor 2 rationalize peptide and small-molecule agonist recognition and receptor activation. Nature communications, 2021, 02-05, Volume: 12, Issue:1 Topics: Aminopyridines; Azepines; Binding Sites; Cloning, Molecular; Cryoelectron Microscopy; Escherichia coli; Gene Expression; Genetic Vectors; HEK293 Cells; Humans; Molecular Dynamics Simulation; Orexin Receptor Antagonists; Orexin Receptors; Peptides; Protein Binding; Protein Conformation, alpha-Helical; Protein Conformation, beta-Strand; Protein Interaction Domains and Motifs; Recombinant Proteins; Sleep Aids, Pharmaceutical; Sulfonamides; Triazoles	2021
Potentiation of long-acting β Respiratory research, 2021, Oct-19, Volume: 22, Issue:1 Topics: Adrenergic beta-2 Receptor Agonists; Aminopyridines; Benzamides; Benzothiazoles; Budesonide; Cell Line; Chemokines; Cyclic AMP; Cyclic Nucleotide Phosphodiesterases, Type 4; Cyclohexanecarboxylic Acids; Cyclopropanes; Drug Synergism; Drug Therapy, Combination; Epithelial Cells; Formoterol Fumarate; Glucocorticoids; Humans; Lung; Multidrug Resistance-Associated Proteins; Nitriles; Phosphodiesterase 4 Inhibitors; Rolipram; Second Messenger Systems; Triazoles	2021
Identification of novel F508del-CFTR traffic correctors among triazole derivatives. European journal of pharmacology, 2023, Jan-05, Volume: 938 Topics: Aminopyridines; Benzodioxoles; Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance Regulator; Humans; Mutation; Triazoles	2023