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triazoles and adenosine-5'-(n-ethylcarboxamide)

triazoles has been researched along with adenosine-5'-(n-ethylcarboxamide) in 66 studies

Research

Studies (66)

Timeframe	Studies, this research(%)	All Research%
pre-1990	1 (1.52)	18.7374
1990's	23 (34.85)	18.2507
2000's	32 (48.48)	29.6817
2010's	10 (15.15)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
O'Regan, MH; Perkins, LM; Phillis, JW; Simpson, RE	1
Holtzman, SG; Mumford, GK	1
Holtzman, SG	1
Behnke, N; Müller, W; Neumann, J; Schmitz, W; Scholz, H; Stein, B	1
Browne, RG; Howard, HR; Koe, BK; Lebel, LA; Sarges, R; Seymour, PA	1
Braunwalder, A; Cash, WD; Francis, J; Ghai, G; Psychoyos, S; Stone, GA; Williams, M	1
Jarvis, JE; Reeves, JJ; Sheehan, MJ; Strong, P	1
Patel, M; Sheehan, MJ; Strong, P	1
Conti, A; Dionisotti, S; Gatta, F; Ongini, E; Sandoli, D; Zocchi, C	1
Ahlberg, S; Fredholm, BB; Olsson, RA; Parkinson, FE; van der Ploeg, I	1
De Sarro, A; De Sarro, G; Donato Di Paola, E; Falconi, U; Ferreri, G	1
Hourani, SM; Prentice, DJ	1
Cristalli, G; Morelli, M; Pinna, A; Wardas, J	1
Alexander, SP; Cooper, J; Hill, SJ	1
Constantino, MD; Cunha, RA; Ribeiro, JA	1
Hourani, SM; Payne, SL; Prentice, DJ	1
McGrath, JC; Moore, FP; Thomson, NC	1
Biaggioni, I; Feoktistov, I	1
Borea, PA; Dionisotti, S; Gessi, S; Ongini, E; Varani, K	1
Baraldi, PG; Borea, PA; Cacciari, B; Dionisotti, S; Ongini, E; Varani, K	1
Cutler, BS; Dobson, JG; Fenton, RA; Li, Jm; Peyton, BD; Powell, CC; Wheeler, HB	1
Arslan, G; Fredholm, BB; Kull, B; Lorenzen, A; Nilsson, C; Owman, C; Schwabe, U	1
Enyeart, JJ; Xu, L	1
Fei, Q; Loutzenhiser, R; Parker, M; Tang, L	1
Borgeat, P; Bourgoin, SG; Harbour, D; Naccache, PH; Thibault, N	1
Jacobson, KA; Ji, XD; Lvovskiy, D; Melman, N; Webb, TR	1
Abebe, W; Arif Hasan, AZ; Mustafa, SJ	1
Abbracchio, MP; Barbieri, D; Brambilla, R; Cattabeni, F; Ceruti, S; Franceschi, C; Jacobson, KA; Kim, YC; Klotz, KN; Lohse, MJ	1
Albrizio, S; D'Ursi, A; Galoppini, C; Giusti, L; Greco, G; Hamm, HE; Lucacchini, A; Mazzoni, MR; Novellino, E; Rovero, P; Taddei, S; Triolo, A	1
Belardinelli, L; Borea, PA; Gessi, S; Merighi, S; Ongini, E; Portaluppi, F; Varani, K	1
Feoktistov, I; Mustafa, SJ; Olanrewaju, HA; Qin, W; Scemama, JL	1
Breschi, MC; Calderone, V; Martinotti, E; Nieri, P	1
Belem, PC; Chen, JF; Cronstein, B; Elson, G; Fink, JS; Jacobson, M; Leibovich, SJ; Montesinos, C; Pinhal-Enfield, G; Ramanathan, M; Rosania, A; Schwarzschild, MA	1
Borea, PA; Cattabriga, E; Iannotta, V; Manfredini, R; Pancaldi, C; Portaluppi, F; Uluoglu, C; Varani, K	1
Diniz, C; Gonçalves, J; Leal, S	1
Hague, BF; Kindt, TJ; Zhao, TM	1
Abbracchio, MP; Brambilla, R; Ceruti, S; Cottini, L; Fumagalli, M	1
Fredholm, BB; Hellsten, Y; Lynge, J; Nordsborg, N; Schulte, G	1
Baur, F; Fozard, JR; Wolber, C	1
Baraldi, PG; Borea, PA; Cacciari, B; Da Ros, T; Deflorian, F; Gessi, S; Moro, S; Pastorin, G; Spalluto, G; Varani, K	1
Chen, A; Gao, ZG; Gross, AS; Jacobson, KA; Kim, SK; Van Calenbergh, S; Van Rompaey, P	1
Abebe, W; Mozaffari, MS	1
Ho, CM; Ho, ST; Peng, SC; Su, CK; Tsai, SK	1
Diniz, C; Fresco, P; Gonçalves, J; Leal, S	1
Abbracchio, MP; Ceruti, S; Marroni, M; Martini, C; Mazzola, A; Mitro, N; Trincavelli, ML; Tuscano, D	1
Briones, R; Donoso, MV; Huidobro-Toro, JP; López, R; Miranda, R	1
Ansari, HR; Mustafa, SJ; Qin, W; Teng, B	1
Hikichi, T; Kawahara, A; Kitaya, N; Mori, F; Takahashi, J; Yoshida, A	1
Andrisani, OM; Bilodeau, ML; Ji, M; Paris, M	1
Grden, M; Kocbuch, K; Pawelczyk, T; Podgorska, M; Szutowicz, A	1
Hao, I; Leibovich, SJ; Pinhal-Enfield, G; Ramanathan, M	1
Hurley, DJ; Moore, JN; Murray, TF; Sun, WC; Vandenplas, ML	1
Cao, Z; Hurley, DJ; Linden, J; Moore, JN; Murray, TF; Sun, WC; Vandenplas, ML	1
Ansari, HR; Falck, JR; Ledent, C; Mustafa, SJ; Nayeem, MA; Poloyac, SM; Ponnoth, DS; Zeldin, DC	1
Csóka, B; Haskó, G; Leibovich, SJ; Lukashev, D; Luo, W; Ramanathan, M; Sitkovsky, MV	1
Krahn, T; Ledent, C; Mustafa, SJ; Ponnoth, DS; Roush, K; Sanjani, MS	1
Beukers, MW; Guo, D; Ijzerman, AP; Müller, CE; Peeters, MC; van Westen, GJ; Wisse, LE	1
Dip, R; Franchini, M; Wehrli Eser, M; Zhang, L	1
Bennett, K; Edwards, PC; Langmead, CJ; Lebon, G; Leslie, AG; Tate, CG; Warne, T	1
Faldyna, M; Kovaru, F; Kovaru, H; Leva, L; Matiasovic, J; Ondrackova, P	1
Falck, JR; Morisseau, C; Mustafa, SJ; Nayeem, MA; Pradhan, I; Zeldin, DC	1
Frøbert, O; Hedegaard, ER; Mogensen, S; Nielsen, BD; Rembold, CM; Simonsen, U	1
Åqvist, J; Gutiérrez-de-Terán, H; Keränen, H	1
Allard, B; Beavis, PA; Darcy, PK; Henderson, MA; John, LB; Kershaw, MH; Loi, S; Milenkovski, N; Stagg, J	1
Bian, X; Hong, L; Liu, Y; Sun, Y; Teng, T; Xu, J; Xu, Z	1
Ernst, OP; García, AE; Larda, ST; Lyda, B; Neale, C; Pichugin, D; Pomès, R; Prosser, RS; Sljoka, A; Sunahara, RK; Tsuchimura, N; Ye, L	1

Trials

1 trial(s) available for triazoles and adenosine-5'-(n-ethylcarboxamide)

Article	Year
Effects of doxazosin and propranolol on A2A adenosine receptors in essential hypertension. Hypertension (Dallas, Tex. : 1979), 2002, Volume: 40, Issue:6 Topics: Adenosine-5'-(N-ethylcarboxamide); Adult; Antihypertensive Agents; Binding, Competitive; Blood Pressure; Body Mass Index; Cyclic AMP; Diastole; Doxazosin; Female; Humans; Hypertension; Lymphocytes; Male; Middle Aged; Neutrophils; Propranolol; Radioligand Assay; Receptor, Adenosine A2A; Receptors, Purinergic P1; Reference Values; Systole; Treatment Outcome; Triazines; Triazoles	2002

Article

Year

Effects of doxazosin and propranolol on A2A adenosine receptors in essential hypertension.

Hypertension (Dallas, Tex. : 1979), 2002, Volume: 40, Issue:6

Topics: Adenosine-5'-(N-ethylcarboxamide); Adult; Antihypertensive Agents; Binding, Competitive; Blood Pressure; Body Mass Index; Cyclic AMP; Diastole; Doxazosin; Female; Humans; Hypertension; Lymphocytes; Male; Middle Aged; Neutrophils; Propranolol; Radioligand Assay; Receptor, Adenosine A2A; Receptors, Purinergic P1; Reference Values; Systole; Treatment Outcome; Triazines; Triazoles

2002

Other Studies

65 other study(ies) available for triazoles and adenosine-5'-(n-ethylcarboxamide)

Article	Year
Excitatory transmitter amino acid release from the ischemic rat cerebral cortex: effects of adenosine receptor agonists and antagonists. Journal of neurochemistry, 1992, Volume: 58, Issue:5 Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Aspartic Acid; Brain Ischemia; Cerebral Cortex; Glutamates; Glutamic Acid; Male; Neurotransmitter Agents; Purinergic Antagonists; Quinazolines; Rats; Rats, Inbred Strains; Receptors, Purinergic; Triazoles; Xanthines	1992
Do adenosinergic substrates mediate methylxanthine effects upon reinforcement thresholds for electrical brain stimulation in the rat? Brain research, 1991, May-31, Volume: 550, Issue:1 Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Brain; Carbolines; Chlordiazepoxide; Electric Stimulation; Hypothalamic Area, Lateral; Male; Midazolam; Phenylisopropyladenosine; Quinazolines; Rats; Rats, Inbred Strains; Receptors, Purinergic; Reinforcement, Psychology; Self Stimulation; Sensory Thresholds; Theophylline; Triazoles	1991
CGS 15943, a nonxanthine adenosine receptor antagonist: effects on locomotor activity of nontolerant and caffeine-tolerant rats. Life sciences, 1991, Volume: 49, Issue:21 Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Caffeine; Dose-Response Relationship, Drug; Drug Tolerance; Male; Motor Activity; Quinazolines; Rats; Rats, Inbred Strains; Triazoles	1991
Differential antagonism by 1,3-dipropylxanthine-8-cyclopentylxanthine and 9-chloro-2-(2-furanyl)-5,6-dihydro-1,2,4-triazolo(1,5-c)quinazolin-5-im ine of the effects of adenosine derivatives in the presence of isoprenaline on contractile response and cycli The Journal of pharmacology and experimental therapeutics, 1990, Volume: 254, Issue:3 Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Cyclic AMP; Drug Interactions; Electric Stimulation; Female; Guinea Pigs; Heart; Isoproterenol; Male; Myocardial Contraction; Quinazolines; Receptors, Purinergic; Triazoles; Vasodilator Agents; Xanthines	1990
4-Amino[1,2,4]triazolo[4,3-a]quinoxalines. A novel class of potent adenosine receptor antagonists and potential rapid-onset antidepressants. Journal of medicinal chemistry, 1990, Volume: 33, Issue:8 Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Antidepressive Agents; Behavior, Animal; Caffeine; Cats; Cell Membrane; Cerebral Cortex; Chemical Phenomena; Chemistry; Corpus Striatum; Male; Molecular Structure; Motor Activity; Purinergic Antagonists; Quinoxalines; Rats; Receptors, Purinergic; Sleep; Structure-Activity Relationship; Triazoles	1990
Biochemical characterization of the triazoloquinazoline, CGS 15943, a novel, non-xanthine adenosine antagonist. The Journal of pharmacology and experimental therapeutics, 1987, Volume: 241, Issue:2 Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Binding, Competitive; Brain; Guinea Pigs; Kinetics; Neurotransmitter Agents; Pyrazoles; Quinazolines; Rats; Receptors, Purinergic; Triazoles; Xanthines	1987
Further investigations into adenosine A1 receptor-mediated contraction in rat colonic muscularis mucosae and its augmentation by certain alkylxanthine antagonists. British journal of pharmacology, 1995, Volume: 114, Issue:5 Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Colon; Cyclooxygenase Inhibitors; In Vitro Techniques; Indomethacin; Intestinal Mucosa; Muscle Contraction; Muscle, Smooth; Phosphodiesterase Inhibitors; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Quinazolines; Rats; Theophylline; Triazoles; Vasodilator Agents; Xanthines	1995
Failure of CGS15943A to block the hypotensive action of agonists acting at the adenosine A3 receptor. British journal of pharmacology, 1994, Volume: 113, Issue:3 Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Blood Pressure; Female; Phenethylamines; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Quinazolines; Rats; Rats, Wistar; Triazoles	1994
Effects of the new A2 adenosine receptor antagonist 8FB-PTP, an 8 substituted pyrazolo-triazolo-pyrimidine, on in vitro functional models. British journal of pharmacology, 1994, Volume: 112, Issue:2 Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Cattle; In Vitro Techniques; Male; Muscle, Smooth, Vascular; Phosphoric Diester Hydrolases; Platelet Aggregation; Purinergic P1 Receptor Antagonists; Pyrimidines; Quinazolines; Rabbits; Rats; Rats, Sprague-Dawley; Triazoles; Vasodilator Agents; Xanthines	1994
Functional characterization of adenosine A2 receptors in Jurkat cells and PC12 cells using adenosine receptor agonists. Naunyn-Schmiedeberg's archives of pharmacology, 1996, Volume: 353, Issue:3 Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Amino Acid Sequence; Animals; Base Sequence; Binding, Competitive; Colforsin; Cyclic AMP; DNA; Humans; Isotope Labeling; Lethal Dose 50; Leukemia, T-Cell; Molecular Sequence Data; PC12 Cells; Phenethylamines; Polymerase Chain Reaction; Purinergic P1 Receptor Agonists; Quinazolines; Rats; Receptors, Purinergic P1; RNA, Messenger; Triazoles; Tumor Cells, Cultured	1996
Repeated treatment with adenosine A1 receptor agonist and antagonist modifies the anticonvulsant properties of CPPene. European journal of pharmacology, 1996, Dec-19, Volume: 317, Issue:2-3 Topics: Acoustic Stimulation; Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Anticonvulsants; Dose-Response Relationship, Drug; Excitatory Amino Acid Antagonists; Injections, Intraventricular; Male; Mice; Mice, Inbred DBA; Piperazines; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Pyrimidines; Triazoles; Xanthines	1996
Adenosine analogues relax guinea-pig taenia caeci via an adenosine A2B receptor and a xanthine-resistant site. European journal of pharmacology, 1997, Mar-26, Volume: 323, Issue:1 Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Cecum; Dose-Response Relationship, Drug; Guinea Pigs; Male; Muscle Relaxation; Muscle, Smooth; Phenethylamines; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Theophylline; Triazines; Triazoles; Vasodilator Agents; Xanthines	1997
Adenosine A2A receptor agonists increase Fos-like immunoreactivity in mesolimbic areas. Brain research, 1997, Jun-06, Volume: 759, Issue:1 Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Dopamine Agonists; Immunohistochemistry; Limbic System; Male; Oxidopamine; Phenethylamines; Proto-Oncogene Proteins c-fos; Purinergic Antagonists; Purinergic P1 Receptor Agonists; Pyrimidines; Quinpirole; Rats; Rats, Sprague-Dawley; Triazoles	1997
An endogenous A2B adenosine receptor coupled to cyclic AMP generation in human embryonic kidney (HEK 293) cells. British journal of pharmacology, 1997, Volume: 122, Issue:3 Topics: 2-Chloroadenosine; Adenosine; Adenosine-5'-(N-ethylcarboxamide); Cells, Cultured; Cyclic AMP; DNA, Complementary; Gene Amplification; Humans; In Vitro Techniques; Kidney; Phenethylamines; Polymerase Chain Reaction; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Quinazolines; Receptor, Adenosine A2B; Receptors, Purinergic P1; Triazoles	1997
ZM241385 is an antagonist of the facilitatory responses produced by the A2A adenosine receptor agonists CGS21680 and HENECA in the rat hippocampus. British journal of pharmacology, 1997, Volume: 122, Issue:7 Topics: Acetylcholine; Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Antihypertensive Agents; Binding Sites; Hippocampus; Ligands; Membranes; Phenethylamines; Platelet Aggregation Inhibitors; Purinergic P1 Receptor Agonists; Rats; Synaptic Transmission; Synaptosomes; Triazines; Triazoles; Visual Cortex	1997
Activation of two sites by adenosine receptor agonists to cause relaxation in rat isolated mesenteric artery. British journal of pharmacology, 1997, Volume: 122, Issue:7 Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Anti-Arrhythmia Agents; Dinucleoside Phosphates; Dose-Response Relationship, Drug; Male; Mesenteric Arteries; Purinergic P1 Receptor Agonists; Rats; Rats, Wistar; Receptors, Purinergic P1; Theophylline; Triazines; Triazoles; Vasodilation; Vasodilator Agents	1997
Adenosine A1 receptor-mediated activation of AMP-activated protein kinase in bovine bronchial rings. Biochemical Society transactions, 1997, Volume: 25, Issue:4 Topics: Adenosine-5'-(N-ethylcarboxamide); Aminoimidazole Carboxamide; AMP-Activated Protein Kinases; Animals; Bronchi; Cattle; Enzyme Activation; In Vitro Techniques; Multienzyme Complexes; Phenylisopropyladenosine; Protein Kinases; Protein Serine-Threonine Kinases; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Receptors, Purinergic P1; Ribonucleotides; Triazines; Triazoles; Xanthines	1997
Pharmacological characterization of adenosine A2B receptors: studies in human mast cells co-expressing A2A and A2B adenosine receptor subtypes. Biochemical pharmacology, 1998, Mar-01, Volume: 55, Issue:5 Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Calcium; Cyclic AMP; Dose-Response Relationship, Drug; Humans; Mast Cells; Phenethylamines; Pyrimidines; Receptors, Purinergic P1; Triazoles; Tumor Cells, Cultured	1998
[3H]-SCH 58261 labelling of functional A2A adenosine receptors in human neutrophil membranes. British journal of pharmacology, 1998, Volume: 123, Issue:8 Topics: Adenosine-5'-(N-ethylcarboxamide); Cell Membrane; Cyclic AMP; Entropy; Humans; In Vitro Techniques; Kinetics; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Pyrimidines; Receptors, Purinergic P1; Superoxides; Triazoles	1998
Binding affinity of adenosine receptor agonists and antagonists at human cloned A3 adenosine receptors. Life sciences, 1998, Volume: 63, Issue:5 Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Binding, Competitive; Cell Line; Cloning, Molecular; Humans; Kidney; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Pyrimidines; Quinazolines; Receptor, Adenosine A3; Receptors, Purinergic P1; Transfection; Triazines; Triazoles	1998
Adenosine A2a receptors increase arterial endothelial cell nitric oxide. The Journal of surgical research, 1998, Volume: 80, Issue:2 Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Carotid Arteries; Cells, Cultured; Endothelium, Vascular; Humans; Iliac Artery; Nitric Oxide; Phenethylamines; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Quinazolines; Receptor, Adenosine A2A; Receptors, Purinergic P1; Swine; Triazines; Triazoles; Xanthines	1998
Differences in the order of potency for agonists but not antagonists at human and rat adenosine A2A receptors. Biochemical pharmacology, 1999, Jan-01, Volume: 57, Issue:1 Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Binding, Competitive; CHO Cells; Cloning, Molecular; Cricetinae; Cyclic AMP; Humans; Kinetics; PC12 Cells; Phenethylamines; Polymerase Chain Reaction; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Pyrimidines; Radioligand Assay; Rats; Receptor, Adenosine A2A; Receptor, Adenosine A2B; Receptors, Purinergic P1; Recombinant Proteins; RNA, Messenger; Transcription, Genetic; Transfection; Triazoles; Tritium	1999
Adenosine inhibits a non-inactivating K+ current in bovine adrenal cortical cells by activation of multiple P1 receptors. The Journal of physiology, 1999, Nov-15, Volume: 521 Pt 1 Topics: Adenosine; Adenosine Triphosphate; Adenosine-5'-(N-ethylcarboxamide); Animals; Cattle; GTP-Binding Proteins; In Vitro Techniques; Male; Membrane Potentials; Patch-Clamp Techniques; Potassium; Potassium Channel Blockers; Potassium Channels; Receptors, Purinergic P1; Signal Transduction; Triazines; Triazoles; Xanthines; Zona Fasciculata	1999
Afferent arteriolar adenosine A2a receptors are coupled to KATP in in vitro perfused hydronephrotic rat kidney. The American journal of physiology, 1999, Volume: 277, Issue:6 Topics: 4-(3-Butoxy-4-methoxybenzyl)-2-imidazolidinone; Adenosine; Adenosine Triphosphate; Adenosine-5'-(N-ethylcarboxamide); Animals; Arterioles; Blood Pressure; Enzyme Inhibitors; Hydronephrosis; Kidney; Perfusion; Potassium Channels; Potassium Chloride; Rats; Receptor, Adenosine A2A; Receptors, Purinergic P1; Renal Artery; Renal Circulation; Triazines; Triazoles; Vasoconstriction; Vasodilation; Vasodilator Agents; Xanthines	1999
Adenosine receptor occupancy suppresses chemoattractant-induced phospholipase D activity by diminishing membrane recruitment of small GTPases. Blood, 2000, Jan-15, Volume: 95, Issue:2 Topics: Adenosine; Adenosine Deaminase; Adenosine-5'-(N-ethylcarboxamide); ADP-Ribosylation Factor 1; Adult; Caffeine; Cell Membrane; Enzyme Activation; GTP Phosphohydrolases; Humans; In Vitro Techniques; Isoenzymes; Kinetics; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Phenethylamines; Phospholipase D; Protein Kinase C; Protein Kinase C-alpha; Purinergic P1 Receptor Antagonists; Quinazolines; Receptor, Adenosine A2A; Receptors, Purinergic P1; rhoA GTP-Binding Protein; Triazoles	2000
The utilization of a unified pharmacophore query in the discovery of new antagonists of the adenosine receptor family. Bioorganic & medicinal chemistry letters, 2000, Jan-03, Volume: 10, Issue:1 Topics: Adenosine-5'-(N-ethylcarboxamide); Databases, Factual; Flavonoids; Guanosine 5'-O-(3-Thiotriphosphate); Information Storage and Retrieval; Kinetics; Ligands; Molecular Conformation; Purinergic P1 Receptor Antagonists; Quinazolines; Receptor, Adenosine A3; Receptors, Purinergic P1; Structure-Activity Relationship; Triazoles	2000
Antagonism of coronary artery relaxation by adenosine A2A-receptor antagonist ZM241385. Journal of cardiovascular pharmacology, 2000, Volume: 35, Issue:2 Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Antihypertensive Agents; Coronary Vessels; Dinoprost; Dose-Response Relationship, Drug; Drug Interactions; Endothelium, Vascular; In Vitro Techniques; Male; Muscle Relaxation; Muscle, Smooth, Vascular; Phenethylamines; Purinergic P1 Receptor Antagonists; Pyrimidines; Receptors, Purinergic P1; Swine; Triazines; Triazoles; Vasodilator Agents	2000
Activation of the A3 adenosine receptor affects cell cycle progression and cell growth. Naunyn-Schmiedeberg's archives of pharmacology, 2000, Volume: 361, Issue:3 Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Adenylyl Cyclases; Analysis of Variance; Animals; Antineoplastic Agents; Cell Cycle; Cell Line; Cell Membrane; Cell Survival; CHO Cells; Cricetinae; Dihydropyridines; Flow Cytometry; Humans; Purinergic P1 Receptor Antagonists; Quinazolines; Receptor, Adenosine A3; Receptors, Purinergic P1; Transfection; Triazoles	2000
A galpha(s) carboxyl-terminal peptide prevents G(s) activation by the A(2A) adenosine receptor. Molecular pharmacology, 2000, Volume: 58, Issue:1 Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Binding, Competitive; Cell Membrane; GTP-Binding Protein alpha Subunits, Gs; In Vitro Techniques; Magnetic Resonance Spectroscopy; Male; Molecular Sequence Data; Peptides; Phenethylamines; Protein Conformation; Pyrimidines; Radioligand Assay; Rats; Rats, Sprague-Dawley; Receptor, Adenosine A2A; Receptors, Purinergic P1; Signal Transduction; Triazoles; Tritium	2000
Dose and time effects of caffeine intake on human platelet adenosine A(2A) receptors : functional and biochemical aspects. Circulation, 2000, Jul-18, Volume: 102, Issue:3 Topics: Adenosine-5'-(N-ethylcarboxamide); Adult; Blood Platelets; Caffeine; Calcium; Cyclic AMP; Dose-Response Relationship, Drug; Female; Humans; Male; Middle Aged; Myocardium; Platelet Aggregation; Platelet Aggregation Inhibitors; Purinergic P1 Receptor Agonists; Pyrimidines; Receptor, Adenosine A2A; Receptors, Purinergic P1; Time Factors; Triazoles; Up-Regulation	2000
Adenosine A(2A) and A(2B) receptors in cultured human and porcine coronary artery endothelial cells. American journal of physiology. Heart and circulatory physiology, 2000, Volume: 279, Issue:2 Topics: 2-Chloroadenosine; Adenosine; Adenosine-5'-(N-ethylcarboxamide); Affinity Labels; Animals; Binding, Competitive; Cells, Cultured; Coronary Vessels; Cyclic AMP; Endothelium, Vascular; Gene Expression Regulation; Humans; Iodine Radioisotopes; Iodobenzenes; Kinetics; Phenethylamines; Purinergic P1 Receptor Antagonists; Radioligand Assay; Receptor, Adenosine A2A; Receptor, Adenosine A2B; Receptors, Purinergic P1; Reverse Transcriptase Polymerase Chain Reaction; Swine; Transcription, Genetic; Triazines; Triazoles	2000
Adenosine-mediated hypotension in in vivo guinea-pig: receptors involved and role of NO. British journal of pharmacology, 2001, Volume: 134, Issue:4 Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Blood Pressure; Diphenhydramine; Dose-Response Relationship, Drug; Enzyme Inhibitors; Guinea Pigs; Heart Rate; Hypotension; Male; Methylene Blue; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Phenethylamines; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Receptors, Purinergic P1; Theophylline; Triazines; Triazoles; Vasodilator Agents; Xanthines	2001
Synergistic up-regulation of vascular endothelial growth factor expression in murine macrophages by adenosine A(2A) receptor agonists and endotoxin. The American journal of pathology, 2002, Volume: 160, Issue:6 Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Blotting, Western; Cells, Cultured; Drosophila Proteins; Endothelial Growth Factors; Female; Interferon-gamma; Lipopolysaccharides; Lymphokines; Macrophages, Peritoneal; Male; Membrane Glycoproteins; Mice; Mice, Inbred C3H; Mice, Inbred C57BL; Mice, Knockout; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Phenethylamines; Protein Kinase Inhibitors; Purinergic P1 Receptor Agonists; Receptor, Adenosine A2A; Receptors, Cell Surface; Receptors, Purinergic P1; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Signal Transduction; Theobromine; Toll-Like Receptor 4; Toll-Like Receptors; Triazines; Triazoles; Up-Regulation; Vascular Endothelial Growth Factor A; Vascular Endothelial Growth Factors; Xanthines	2002
Regional differences in the adenosine A(2) receptor-mediated modulation of contractions in rat vas deferens. European journal of pharmacology, 2003, Jan-24, Volume: 460, Issue:2-3 Topics: Adenosine; Adenosine Triphosphate; Adenosine-5'-(N-ethylcarboxamide); Animals; Epididymis; Immunohistochemistry; In Vitro Techniques; Male; Muscle Contraction; Norepinephrine; Phenethylamines; Prostate; Rats; Rats, Wistar; Receptor, Adenosine A2A; Receptors, Purinergic P1; Theobromine; Triazines; Triazoles; Vas Deferens; Xanthines	2003
Binding of HTLV-1 virions to T cells occurs by a temperature and calcium-dependent process and is blocked by certain type 2 adenosine receptor antagonists. Virus research, 2003, Volume: 93, Issue:1 Topics: 2-Chloroadenosine; Adenosine; Adenosine-5'-(N-ethylcarboxamide); Antibodies, Monoclonal; Calcium; Cations, Divalent; Cell Line, Transformed; Human T-lymphotropic virus 1; Humans; Kinetics; Membrane Microdomains; Phenethylamines; Purinergic P1 Receptor Agonists; Quinazolines; T-Lymphocytes; Thermodynamics; Triazoles	2003
Blockade of A2A adenosine receptors prevents basic fibroblast growth factor-induced reactive astrogliosis in rat striatal primary astrocytes. Glia, 2003, Volume: 43, Issue:2 Topics: Adenosine; Adenosine A2 Receptor Agonists; Adenosine A2 Receptor Antagonists; Adenosine-5'-(N-ethylcarboxamide); Animals; Animals, Newborn; Astrocytes; Cell Division; Cells, Cultured; Cerebral Cortex; Corpus Striatum; Dose-Response Relationship, Drug; Drug Interactions; Fibroblast Growth Factor 2; Fluorescent Antibody Technique; Glial Fibrillary Acidic Protein; Gliosis; Neuroprotective Agents; Phenethylamines; Purines; Pyrimidines; Rats; Receptor, Adenosine A2A; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Triazoles; Vasodilator Agents	2003
Adenosine A 2B receptors modulate cAMP levels and induce CREB but not ERK1/2 and p38 phosphorylation in rat skeletal muscle cells. Biochemical and biophysical research communications, 2003, Jul-18, Volume: 307, Issue:1 Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Cells, Cultured; Cyclic AMP; Cyclic AMP Response Element-Binding Protein; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; Muscle, Skeletal; p38 Mitogen-Activated Protein Kinases; Pertussis Toxin; Phenethylamines; Phosphorylation; Rats; Receptor, Adenosine A2A; Receptor, Adenosine A2B; Receptors, Purinergic P1; RNA; Triazines; Triazoles	2003
Antagonist pharmacology of adenosine A2B receptors from rat, guinea pig and dog. European journal of pharmacology, 2003, Aug-15, Volume: 475, Issue:1-3 Topics: Adenosine A2 Receptor Antagonists; Adenosine-5'-(N-ethylcarboxamide); Animals; Dogs; Dose-Response Relationship, Drug; Female; Guinea Pigs; In Vitro Techniques; Male; Muscle Relaxation; Quinazolines; Rats; Receptor, Adenosine A2B; Species Specificity; Triazoles	2003
Pyrazolo[4,3-e]-1,2,4-triazolo[1,5-c]pyrimidine derivatives as adenosine receptor antagonists. Influence of the N5 substituent on the affinity at the human A 3 and A 2B adenosine receptor subtypes: a molecular modeling investigation. Journal of medicinal chemistry, 2003, Sep-25, Volume: 46, Issue:20 Topics: Adenosine-5'-(N-ethylcarboxamide); Animals; Binding, Competitive; CHO Cells; Cricetinae; Cyclic AMP; Drug Design; Humans; Inhibitory Concentration 50; Models, Molecular; Purinergic P1 Receptor Antagonists; Pyrazoles; Pyrimidines; Receptor, Adenosine A2B; Receptor, Adenosine A3; Receptors, Purinergic P1; Structure-Activity Relationship; Triazoles	2003
Modeling the adenosine receptors: comparison of the binding domains of A2A agonists and antagonists. Journal of medicinal chemistry, 2003, Nov-06, Volume: 46, Issue:23 Topics: Adenosine A2 Receptor Agonists; Adenosine A2 Receptor Antagonists; Adenosine-5'-(N-ethylcarboxamide); Animals; Binding Sites; COS Cells; Humans; Hydrogen Bonding; Hydrophobic and Hydrophilic Interactions; Ligands; Models, Molecular; Mutagenesis, Site-Directed; Protein Conformation; Quinazolines; Radioligand Assay; Receptors, Adenosine A2; Triazoles	2003
Effect of taurine deficiency on adenosine receptor-mediated relaxation of the rat aorta. Vascular pharmacology, 2003, Volume: 40, Issue:4 Topics: 2-Chloroadenosine; Acetylcholine; Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Aorta, Thoracic; beta-Alanine; Endothelium, Vascular; Enzyme Inhibitors; In Vitro Techniques; Male; Muscle Relaxation; Muscle, Smooth, Vascular; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Nitric Oxide Synthase Type III; Phenylephrine; Rats; Rats, Inbred WKY; Receptors, Purinergic P1; Taurine; Triazines; Triazoles; Vasoconstrictor Agents; Vasodilator Agents	2003
The role of intraspinal adenosine A1 receptors in sympathetic regulation. European journal of pharmacology, 2004, May-10, Volume: 492, Issue:1 Topics: Adenosine; Adenosine A1 Receptor Agonists; Adenosine A1 Receptor Antagonists; Adenosine A2 Receptor Agonists; Adenosine A2 Receptor Antagonists; Adenosine A3 Receptor Agonists; Adenosine A3 Receptor Antagonists; Adenosine-5'-(N-ethylcarboxamide); Animals; Dihydropyridines; Rats; Rats, Sprague-Dawley; Receptor, Adenosine A1; Spinal Cord; Splanchnic Nerves; Sympathetic Nervous System; Synaptic Transmission; Theobromine; Theophylline; Triazines; Triazoles	2004
Adenosine receptors involved in modulation of noradrenaline release in isolated rat tail artery. European journal of pharmacology, 2004, Nov-03, Volume: 504, Issue:1-2 Topics: Adenosine-5'-(N-ethylcarboxamide); Animals; Arteries; Dose-Response Relationship, Drug; Male; Norepinephrine; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Pyrimidines; Rats; Receptors, Purinergic P1; Tail; Triazoles	2004
Regulation of A2B adenosine receptor functioning by tumour necrosis factor a in human astroglial cells. Journal of neurochemistry, 2004, Volume: 91, Issue:5 Topics: Adenosine; Adenosine A2 Receptor Antagonists; Adenosine-5'-(N-ethylcarboxamide); Animals; Antineoplastic Agents; Astrocytes; Astrocytoma; Blotting, Western; Cell Growth Processes; Cell Line, Tumor; Cricetinae; Cricetulus; Cyclic AMP; Dose-Response Relationship, Drug; Enzyme Inhibitors; Gene Expression Regulation; Guanosine 5'-O-(3-Thiotriphosphate); Humans; Immunoprecipitation; Neuroprotective Agents; Phenethylamines; Purines; Pyrimidines; Radioligand Assay; Receptor, Adenosine A2B; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Threonine; Time Factors; Transfection; Triazoles; Tumor Necrosis Factor-alpha	2004
A2B adenosine receptor mediates human chorionic vasoconstriction and signals through arachidonic acid cascade. American journal of physiology. Heart and circulatory physiology, 2005, Volume: 288, Issue:5 Topics: Adenosine; Adenosine A2 Receptor Antagonists; Adenosine-5'-(N-ethylcarboxamide); Arachidonic Acid; Chorion; Endothelium, Vascular; Female; Humans; In Vitro Techniques; Placenta; Pregnancy; Receptor, Adenosine A2B; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Signal Transduction; Triazines; Triazoles; Vasoconstriction; Vasodilator Agents; Xanthines	2005
Involvement of p38-mitogen-activated protein kinase in adenosine receptor-mediated relaxation of coronary artery. American journal of physiology. Heart and circulatory physiology, 2005, Volume: 288, Issue:6 Topics: Adenosine-5'-(N-ethylcarboxamide); Animals; Coronary Vessels; In Vitro Techniques; p38 Mitogen-Activated Protein Kinases; Pyrimidines; Receptors, Purinergic P1; Swine; Triazoles; Vasodilation	2005
Adenosine agonist regulation of outward active transport of fluorescein across retinal pigment epithelium in rabbits. Experimental eye research, 2005, Volume: 80, Issue:4 Topics: Adenosine; Adenosine A1 Receptor Antagonists; Adenosine A2 Receptor Antagonists; Adenosine A3 Receptor Antagonists; Adenosine-5'-(N-ethylcarboxamide); Animals; Biological Transport, Active; Dihydropyridines; Fluorescein; Fluoresceins; Fluorophotometry; Injections, Intravenous; Male; Pigment Epithelium of Eye; Purinergic P1 Receptor Antagonists; Rabbits; Retinal Detachment; Triazines; Triazoles; Xanthines	2005
Adenosine signaling promotes neuronal, catecholaminergic differentiation of primary neural crest cells and CNS-derived CAD cells. Molecular and cellular neurosciences, 2005, Volume: 29, Issue:3 Topics: 1-Methyl-3-isobutylxanthine; Adenosine; Adenosine A2 Receptor Agonists; Adenosine A2 Receptor Antagonists; Adenosine Deaminase; Adenosine Deaminase Inhibitors; Adenosine-5'-(N-ethylcarboxamide); Adrenal Medulla; Animals; Bone Morphogenetic Protein 2; Bone Morphogenetic Proteins; Catecholamines; Cell Differentiation; Cell Line; Cells, Cultured; Chromaffin Cells; Coturnix; Culture Media, Serum-Free; Cyclic AMP; Neural Crest; Neurons; Quinazolines; Receptor, Adenosine A2A; Receptor, Adenosine A2B; Signal Transduction; Sympathetic Nervous System; Transforming Growth Factor beta; Triazoles; Tyrosine 3-Monooxygenase	2005
Expression of adenosine receptors in cardiac fibroblasts as a function of insulin and glucose level. Archives of biochemistry and biophysics, 2006, Nov-01, Volume: 455, Issue:1 Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Adenylyl Cyclases; Animals; Blotting, Western; Cells, Cultured; Cyclic AMP; Dose-Response Relationship, Drug; Fibroblasts; Gene Expression; Glucose; Heart Ventricles; Insulin; Male; Phenethylamines; Protein Isoforms; Rats; Rats, Wistar; Receptors, Purinergic P1; RNA, Messenger; Triazines; Triazoles	2006
Synergistic up-regulation of vascular endothelial growth factor (VEGF) expression in macrophages by adenosine A2A receptor agonists and endotoxin involves transcriptional regulation via the hypoxia response element in the VEGF promoter. Molecular biology of the cell, 2007, Volume: 18, Issue:1 Topics: Adenosine A2 Receptor Agonists; Adenosine A2 Receptor Antagonists; Adenosine-5'-(N-ethylcarboxamide); Animals; Cell Hypoxia; DNA; Exons; Female; Hypoxia-Inducible Factor 1, alpha Subunit; Lipopolysaccharides; Macrophages; Mice; NF-kappa B; Response Elements; RNA, Messenger; Sequence Deletion; Toll-Like Receptor 4; Transcription, Genetic; Triazines; Triazoles; Tumor Necrosis Factor-alpha; Up-Regulation; Vascular Endothelial Growth Factor A	2007
Effects of stimulation of adenosine A2A receptors on lipopolysaccharide-induced production of reactive oxygen species by equine neutrophils. American journal of veterinary research, 2007, Volume: 68, Issue:6 Topics: Adenosine A2 Receptor Agonists; Adenosine A2 Receptor Antagonists; Adenosine-5'-(N-ethylcarboxamide); Animals; Cyclic AMP; Dose-Response Relationship, Drug; Horses; Lipopolysaccharides; Neutrophils; Reactive Oxygen Species; Receptor, Adenosine A2A; Rolipram; Triazines; Triazoles	2007
Adenosine A2A receptor agonists inhibit lipopolysaccharide-induced production of tumor necrosis factor-alpha by equine monocytes. Veterinary immunology and immunopathology, 2008, Jan-15, Volume: 121, Issue:1-2 Topics: Adenosine; Adenosine A2 Receptor Agonists; Adenosine-5'-(N-ethylcarboxamide); Animals; Binding, Competitive; Cyclic AMP; Horses; Immunoenzyme Techniques; Lipopolysaccharides; Monocytes; Phenethylamines; Piperidines; Receptor, Adenosine A2A; Regression Analysis; Triazines; Triazoles; Tumor Necrosis Factor-alpha	2008
Role of CYP epoxygenases in A2A AR-mediated relaxation using A2A AR-null and wild-type mice. American journal of physiology. Heart and circulatory physiology, 2008, Volume: 295, Issue:5 Topics: 8,11,14-Eicosatrienoic Acid; Acetylcholine; Adenosine; Adenosine-5'-(N-ethylcarboxamide); Amides; Amidines; Animals; Aorta; Arachidonic Acid; Chromatography, Liquid; Cytochrome P-450 CYP4A; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Cytochrome P450 Family 2; Dose-Response Relationship, Drug; Enzyme Inhibitors; Indomethacin; Male; Mice; Mice, Knockout; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Phenethylamines; Prostaglandin-Endoperoxide Synthases; Pyrimidines; Receptor, Adenosine A2A; Tandem Mass Spectrometry; Triazoles; Vasoconstriction; Vasoconstrictor Agents; Vasodilation; Vasodilator Agents	2008
Differential regulation of HIF-1alpha isoforms in murine macrophages by TLR4 and adenosine A(2A) receptor agonists. Journal of leukocyte biology, 2009, Volume: 86, Issue:3 Topics: Adenosine; Adenosine A2 Receptor Agonists; Adenosine A2 Receptor Antagonists; Adenosine-5'-(N-ethylcarboxamide); Animals; Cells, Cultured; Drug Combinations; Female; Gene Expression Regulation; Genes, Reporter; Hypoxia-Inducible Factor 1, alpha Subunit; Lipopolysaccharides; Luciferases, Renilla; Macrophages, Peritoneal; Mice; Mice, Congenic; Mice, Inbred C57BL; NF-kappa B; Nitriles; Phenethylamines; Protein Isoforms; Purinergic P1 Receptor Agonists; RNA, Messenger; Sulfones; Toll-Like Receptor 4; Transfection; Triazines; Triazoles; Vascular Endothelial Growth Factor A	2009
Absence of adenosine-mediated aortic relaxation in A(2A) adenosine receptor knockout mice. American journal of physiology. Heart and circulatory physiology, 2009, Volume: 297, Issue:5 Topics: Acetylcholine; Adenosine; Adenosine-5'-(N-ethylcarboxamide); Aminopyridines; Animals; Aorta; Dose-Response Relationship, Drug; Endothelium, Vascular; Female; Flavins; Gene Expression Regulation; In Vitro Techniques; Male; Mice; Mice, Knockout; Phenethylamines; Pyrimidines; Receptor, Adenosine A1; Receptor, Adenosine A2A; Receptor, Adenosine A2B; Triazoles; Vasoconstriction; Vasoconstrictor Agents; Vasodilation; Vasodilator Agents; Xanthines	2009
GPCR structure and activation: an essential role for the first extracellular loop in activating the adenosine A2B receptor. FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 2011, Volume: 25, Issue:2 Topics: Adenosine A2 Receptor Agonists; Adenosine A2 Receptor Antagonists; Adenosine-5'-(N-ethylcarboxamide); Amino Acid Sequence; Aminopyridines; Gene Expression Regulation; Humans; Models, Molecular; Molecular Structure; Mutagenesis, Site-Directed; Protein Conformation; Receptor, Adenosine A2B; Saccharomyces cerevisiae; Triazines; Triazoles	2011
Enhanced IL-6 transcriptional response to adenosine receptor ligands in horses with lower airway inflammation. Equine veterinary journal, 2012, Volume: 44, Issue:1 Topics: Adenosine-5'-(N-ethylcarboxamide); Animals; Bronchoalveolar Lavage Fluid; Cells, Cultured; Female; Gene Expression Regulation; Horse Diseases; Horses; Interleukin-6; Lung Diseases; Male; Purinergic P1 Receptor Antagonists; Pyrimidines; Receptor, Adenosine A2A; Receptor, Adenosine A2B; Transcriptome; Triazoles; Vasodilator Agents	2012
Agonist-bound adenosine A2A receptor structures reveal common features of GPCR activation. Nature, 2011, May-18, Volume: 474, Issue:7352 Topics: Adenosine; Adenosine A2 Receptor Agonists; Adenosine-5'-(N-ethylcarboxamide); Animals; Binding Sites; CHO Cells; Cricetinae; Cricetulus; Crystallography, X-Ray; Drug Inverse Agonism; Humans; Ligands; Models, Molecular; Molecular Conformation; Receptor, Adenosine A2A; Triazines; Triazoles	2011
The effect of adenosine on pro-inflammatory cytokine production by porcine T cells. Veterinary immunology and immunopathology, 2012, Jan-15, Volume: 145, Issue:1-2 Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; CD3 Complex; CD4-Positive T-Lymphocytes; CD8-Positive T-Lymphocytes; Concanavalin A; Dose-Response Relationship, Drug; Flow Cytometry; Inflammation; Interferon-gamma; Interleukin-10; Interleukin-2; Quinazolines; Swine; T-Lymphocyte Subsets; T-Lymphocytes; Triazoles; Tumor Necrosis Factor-alpha	2012
Adenosine A2A receptor modulates vascular response in soluble epoxide hydrolase-null mice through CYP-epoxygenases and PPARγ. American journal of physiology. Regulatory, integrative and comparative physiology, 2013, Jan-01, Volume: 304, Issue:1 Topics: 8,11,14-Eicosatrienoic Acid; Adamantane; Adenosine; Adenosine A2 Receptor Agonists; Adenosine A2 Receptor Antagonists; Adenosine-5'-(N-ethylcarboxamide); Animals; Benzamides; Benzoates; Butyrates; Enzyme Inhibitors; Epoxide Hydrolases; Female; Gene Silencing; Lauric Acids; Male; Mice; NG-Nitroarginine Methyl Ester; Oxygenases; Phenethylamines; Phenylurea Compounds; PPAR gamma; Pyridines; Pyrimidines; Receptor, Adenosine A2A; Triazines; Triazoles; Urea; Vasodilation; Vasodilator Agents	2013
Mechanisms involved in increased sensitivity to adenosine A(2A) receptor activation and hypoxia-induced vasodilatation in porcine coronary arteries. European journal of pharmacology, 2014, Jan-15, Volume: 723 Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Coronary Vessels; Cyclic AMP; Dinoprost; HSP20 Heat-Shock Proteins; Hypoxia; In Vitro Techniques; Oxygen; Phenethylamines; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Receptors, Purinergic P1; Swine; Triazines; Triazoles; Vasodilation	2014
Structural and energetic effects of A2A adenosine receptor mutations on agonist and antagonist binding. PloS one, 2014, Volume: 9, Issue:10 Topics: Adenosine A2 Receptor Agonists; Adenosine A2 Receptor Antagonists; Adenosine-5'-(N-ethylcarboxamide); Binding Sites; Humans; Ligands; Mutant Proteins; Mutation; Receptor, Adenosine A2A; Thermodynamics; Triazines; Triazoles	2014
Adenosine Receptor 2A Blockade Increases the Efficacy of Anti-PD-1 through Enhanced Antitumor T-cell Responses. Cancer immunology research, 2015, Volume: 3, Issue:5 Topics: Adenosine A2 Receptor Antagonists; Adenosine-5'-(N-ethylcarboxamide); Animals; Antibodies, Monoclonal; CD8-Positive T-Lymphocytes; Cell Line, Tumor; Humans; Interferon-gamma; Leukocytes, Mononuclear; Mice, Inbred BALB C; Mice, Inbred C57BL; Mice, Transgenic; Programmed Cell Death 1 Receptor; Pyrimidines; Triazoles	2015
Adenosine A Free radical biology & medicine, 2017, Volume: 106 Topics: Adenosine-5'-(N-ethylcarboxamide); Animals; Electron Transport Complex I; Humans; Membrane Potential, Mitochondrial; Mitochondria; Mutation; Myocardial Infarction; Myocardial Reperfusion Injury; Myocytes, Cardiac; NADH Dehydrogenase; Oxidative Stress; Purines; Pyrimidines; Rats; Receptors, Adenosine A2; Triazoles	2017
Mechanistic insights into allosteric regulation of the A Nature communications, 2018, 04-10, Volume: 9, Issue:1 Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Allosteric Regulation; Amino Acid Sequence; Animals; Binding Sites; Calcium; Cations, Divalent; Crystallography, X-Ray; Gene Expression; Humans; Kinetics; Magnesium; Models, Molecular; Molecular Dynamics Simulation; Protein Binding; Protein Conformation, alpha-Helical; Protein Conformation, beta-Strand; Protein Interaction Domains and Motifs; Receptor, Adenosine A2A; Recombinant Proteins; Sf9 Cells; Spodoptera; Thermodynamics; Triazines; Triazoles	2018