triazoles has been researched along with abt-199 in 16 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 9 (56.25) | 24.3611 |
| 2020's | 7 (43.75) | 2.80 |
| Authors | Studies |
|---|---|
| Bertino, JR; Bhagavathi, S; Johnson-Farley, N; Veliz, J | 1 |
| Bendell, J; Brown, JR; Derks, IA; Eichhorst, B; Eldering, E; Fernandes, SM; Filvaroff, EH; Garrick, B; Hallek, M; Hege, K; Kater, AP; Kersten, MJ; Michot, JM; Reinhardt, HC; Rodríguez, MS; Ter Burg, J; Thijssen, R; Trowe, T; van Bochove, GG; van Kampen, RJ | 1 |
| Berx, G; Bornhauser, BC; Bourquin, JP; Dobay, MP; Frismantas, V; Goossens, S; Lintermans, B; Matthijssens, F; Peirs, S; Pieters, T; Poppe, B; Van Loocke, W; Van Vlierberghe, P; Vandamme, N | 1 |
| Agarwal, SK; DiNardo, CD; Dunbar, M; Humerickhouse, RA; Kantarjian, HM; Konopleva, MY; Menon, RM; Potluri, J; Salem, AH; Wong, SL | 1 |
| Elmi, L; Graham, A; Grundy, M; Hall, M; Jones, T; Pallis, M; Russell, N; Seedhouse, C | 1 |
| Aljama, MA; Dingli, D; Sidiqi, MH | 1 |
| Edwards, H; Ge, Y; Lin, H; Liu, S; Luedtke, DA; Su, Y; Taub, JW; Wang, Y | 1 |
| Arribas, AJ; Bertoni, F; Cascione, L; Curti, E; Gaudio, E; Priebe, V; Rossi, D; Spriano, F; Stathis, A; Tarantelli, C; Zhang, L; Zucca, E | 1 |
| Choi, CM; Choi, YJ; Hong, JY; Kim, DH; Lee, JC; Rho, JK; Suh, C; Yoon, DH | 1 |
| Brancaccio, M; Carrà, G; Cartellà, A; Circosta, P; Gaidano, V; Guerrasio, A; Lingua, MF; Maffeo, B; Morotti, A; Nicoli, P; Parvis, G; Saglio, G; Taulli, R | 1 |
| Ahmann, GJ; Bergsagel, PL; Bonolo de Campos, C; Braggio, E; Bruins, LA; Darvish, SA; Dingli, D; Fonseca, R; Henderson, KJ; Kapoor, P; Kruse, JJ; Kumar, SK; Larsen, JT; Lopez Armenta, ID; Meurice, N; Petit, JL; Polito, AN; Reeder, CB; Stewart, AK; Stewart, WM; Tian, S; Wang, P; Wang, X; Zhu, YX | 1 |
| Chen, TT; Cheng, FM; Lin, CC; Tien, JZ; Yeh, SP | 1 |
| Bhatnagar, S; Gibbs, JP; Menon, RM; Miles, D; Mukherjee, D; Salem, AH | 1 |
| Aljoundi, A; Elamin, G; Soliman, MES | 1 |
| Fujita, N; Kameoka, Y; Kitadate, A; Kobayashi, T; Miura, M; Nara, M; Sato, H; Takahashi, N; Yamashita, T; Yoshioka, T | 1 |
| Guarana, M; Nucci, M | 1 |
2 review(s) available for triazoles and abt-199
| Article | Year |
|---|---|
Therapy for relapsed multiple myeloma.
Topics: Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Bridged Bicyclo Compounds, Heterocyclic; Clinical Trials, Phase III as Topic; Decision Making; Gene Expression Profiling; Humans; Hydrazines; Immunotherapy; In Situ Hybridization, Fluorescence; Multiple Myeloma; Neoplasm Recurrence, Local; Stem Cell Transplantation; Sulfonamides; Symptom Assessment; Transplantation, Autologous; Triazoles; Watchful Waiting | 2018 |
Should patients with acute myeloid leukemia treated with venetoclax-based regimens receive antifungal prophylaxis?
Topics: Antifungal Agents; Azoles; Bridged Bicyclo Compounds, Heterocyclic; Humans; Invasive Fungal Infections; Leukemia, Myeloid, Acute; Retrospective Studies; Triazoles | 2023 |
2 trial(s) available for triazoles and abt-199
| Article | Year |
|---|---|
Dual TORK/DNA-PK inhibition blocks critical signaling pathways in chronic lymphocytic leukemia.
Topics: Bridged Bicyclo Compounds, Heterocyclic; DNA-Activated Protein Kinase; Drug Resistance, Neoplasm; Female; Humans; Leukemia, Lymphocytic, Chronic, B-Cell; Male; Neoplasm Proteins; Nuclear Proteins; Purines; Pyrazines; Quinazolinones; Sulfonamides; TOR Serine-Threonine Kinases; Triazoles; Tumor Cells, Cultured; Vidarabine | 2016 |
Management of Venetoclax-Posaconazole Interaction in Acute Myeloid Leukemia Patients: Evaluation of Dose Adjustments.
Topics: Administration, Oral; Adult; Antifungal Agents; Bridged Bicyclo Compounds, Heterocyclic; Cytochrome P-450 CYP3A; Female; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged; Sulfonamides; Triazoles | 2017 |
12 other study(ies) available for triazoles and abt-199
| Article | Year |
|---|---|
ABT-199, a BH3 mimetic that specifically targets Bcl-2, enhances the antitumor activity of chemotherapy, bortezomib and JQ1 in "double hit" lymphoma cells.
Topics: Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Azepines; Biomimetics; Blotting, Western; Bortezomib; Bridged Bicyclo Compounds, Heterocyclic; Cell Proliferation; Drug Synergism; Humans; Lymphoma; Peptide Fragments; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-bcl-2; Sulfonamides; Triazoles; Tumor Cells, Cultured | 2015 |
Targeting BET proteins improves the therapeutic efficacy of BCL-2 inhibition in T-cell acute lymphoblastic leukemia.
Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Azepines; Bcl-2-Like Protein 11; Bridged Bicyclo Compounds, Heterocyclic; Cell Cycle Proteins; Cell Line, Tumor; Drug Synergism; Female; Gene Expression Regulation, Neoplastic; Humans; Mice; Mice, Inbred NOD; Mice, SCID; Molecular Targeted Therapy; Neoplasm Proteins; Nuclear Proteins; Precursor T-Cell Lymphoblastic Leukemia-Lymphoma; Protein Domains; Proto-Oncogene Proteins c-bcl-2; Sulfonamides; Transcription Factors; Triazoles; Xenograft Model Antitumor Assays | 2017 |
Predicting effective pro-apoptotic anti-leukaemic drug combinations using co-operative dynamic BH3 profiling.
Topics: Antineoplastic Agents; Apoptosis; Azepines; Bridged Bicyclo Compounds, Heterocyclic; Cell Line, Tumor; Drug Combinations; Humans; Indoles; Leukemia; Myeloid Cell Leukemia Sequence 1 Protein; Proto-Oncogene Proteins c-bcl-2; Sulfonamides; Triazoles | 2018 |
Inhibition of XPO1 enhances cell death induced by ABT-199 in acute myeloid leukaemia via Mcl-1.
Topics: Adult; Aged; Apoptosis; Bridged Bicyclo Compounds, Heterocyclic; Cell Line, Tumor; Cell Proliferation; Drug Resistance, Neoplasm; Drug Synergism; Exportin 1 Protein; Female; Gene Expression Regulation, Neoplastic; Humans; Hydrazines; Karyopherins; Leukemia, Myeloid, Acute; Male; Middle Aged; Myeloid Cell Leukemia Sequence 1 Protein; Proto-Oncogene Proteins c-bcl-2; Receptors, Cytoplasmic and Nuclear; Sulfonamides; Triazoles | 2018 |
The Bruton tyrosine kinase inhibitor zanubrutinib (BGB-3111) demonstrated synergies with other anti-lymphoma targeted agents.
Topics: Adenine; Agammaglobulinaemia Tyrosine Kinase; Antineoplastic Combined Chemotherapy Protocols; Bridged Bicyclo Compounds, Heterocyclic; Cell Proliferation; Drug Synergism; Humans; Hydrazines; Lymphoma, B-Cell; Lymphoma, Mantle-Cell; Niacinamide; Piperidines; Pyrazoles; Pyrimidines; Sulfonamides; Triazoles; Tumor Cells, Cultured | 2019 |
Efficacy of the novel CDK7 inhibitor QS1189 in mantle cell lymphoma.
Topics: Adenine; Antineoplastic Agents; Bridged Bicyclo Compounds, Heterocyclic; Cell Cycle; Cell Line, Tumor; Cell Proliferation; Cell Survival; Cyclin-Dependent Kinase-Activating Kinase; Cyclin-Dependent Kinases; Drug Resistance, Neoplasm; Drug Synergism; Humans; Lymphoma, Mantle-Cell; Phosphorylation; Piperidines; Pyrazoles; Pyrimidines; RNA Polymerase II; Sulfonamides; Triazoles | 2019 |
Inhibition of bromodomain and extra-terminal proteins increases sensitivity to venetoclax in chronic lymphocytic leukaemia.
Topics: Azepines; Bridged Bicyclo Compounds, Heterocyclic; Cell Line, Tumor; Cell Proliferation; Cell Survival; Drug Synergism; Humans; Leukemia, Lymphocytic, Chronic, B-Cell; Sulfonamides; Transcription Factors; Triazoles | 2020 |
"Direct to Drug" screening as a precision medicine tool in multiple myeloma.
Topics: Antineoplastic Agents; Bridged Bicyclo Compounds, Heterocyclic; Cell Line, Tumor; Drug Screening Assays, Antitumor; Humans; Hydrazines; Multiple Myeloma; Precision Medicine; Sulfonamides; Triazoles; Tumor Cells, Cultured | 2020 |
Venetoclax plus cytochrome P450 inhibitors without ramp-up strategy led to low risk of tumor lysis syndrome in acute myeloid leukemia.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Azacitidine; Bridged Bicyclo Compounds, Heterocyclic; Child; Creatinine; Cytochrome P-450 Enzyme Inhibitors; Drug Administration Schedule; Drug Synergism; Female; Humans; Hyperuricemia; Leukemia, Myeloid, Acute; Male; Middle Aged; Retrospective Studies; Sulfonamides; Triazoles; Tumor Lysis Syndrome; Urate Oxidase; Uric Acid; Young Adult | 2020 |
Dose adjustment of venetoclax when co-administered with posaconazole: clinical drug-drug interaction predictions using a PBPK approach.
Topics: Adult; Bridged Bicyclo Compounds, Heterocyclic; Cytochrome P-450 CYP3A Inhibitors; Drug Interactions; Humans; Middle Aged; Models, Biological; Sulfonamides; Triazoles | 2021 |
Co-Binding of JQ1 and Venetoclax Exhibited Synergetic Inhibitory Effect for Cancer Therapy; Potential Line of Treatment for the Waldenström Macroglobulinemia Lymphoma.
Topics: Antineoplastic Agents; Azepines; Bridged Bicyclo Compounds, Heterocyclic; Humans; Lymphoma; Proto-Oncogene Proteins c-bcl-2; Sulfonamides; Triazoles; Waldenstrom Macroglobulinemia | 2022 |
Safe administration and pharmacokinetic monitoring of crushed venetoclax tablets with posaconazole and clarithromycin via percutaneous endoscopic gastrostomy tube in a patient with acute myeloid leukemia.
Topics: Bridged Bicyclo Compounds, Heterocyclic; Clarithromycin; Gastrostomy; Humans; Leukemia, Myeloid, Acute; Sulfonamides; Tablets; Triazoles | 2022 |