Page last updated: 2024-08-24

triazoles and 5-(3-chloro-4-fluorophenyl)-3-methyl-3-(pyrimidin-5-ylmethyl)-1-(1h-1,2,4-triazol-3-yl)-1,3-dihydro-2h-indol-2-one

triazoles has been researched along with 5-(3-chloro-4-fluorophenyl)-3-methyl-3-(pyrimidin-5-ylmethyl)-1-(1h-1,2,4-triazol-3-yl)-1,3-dihydro-2h-indol-2-one in 5 studies

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's5 (100.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Abbadie, C; Arneric, SP; Bugianesi, RM; Bunting, PB; Dai, G; Duffy, JL; Eduljee, C; Euan MacIntyre, D; Haedo, RJ; Herrington, JB; Hoyt, SB; Jochnowitz, N; Kaczorowski, GJ; Liang, A; London, C; Lyons, KA; McGowan, E; McManus, OB; Mistry, S; Smith, MM; Snutch, TP; Sun, SY; Swensen, AM; Tringham, EW; Volksdorf, S; Warren, VA; White, VV; Williams, B1
Arneric, SP; Bugianesi, RM; Dai, G; Duffy, JL; Eduljee, C; Haedo, RJ; Herrington, J; Hoyt, SB; Kaczorowski, GJ; London, C; McManus, OB; Parker, D; Ratliff, KS; Smith, MM; Snutch, TP; Swensen, AM; Warren, VA1
Jarvis, MF; Lee, L; Li, T; McGaraughty, S; Niforatos, W; Perner, RJ; Schrimpf, MR; Scott, VE; Swensen, AM; Vortherms, TA1
Christoph, T; Damann, N; Dickenson, AH; Patel, R; Rutten, K; Schiene, K; Schunk, S; Valdor, M; Wigge, S1
Dickenson, AH; Patel, R; Rahman, W1

Other Studies

5 other study(ies) available for triazoles and 5-(3-chloro-4-fluorophenyl)-3-methyl-3-(pyrimidin-5-ylmethyl)-1-(1h-1,2,4-triazol-3-yl)-1,3-dihydro-2h-indol-2-one

ArticleYear
Analgesic effects of a substituted N-triazole oxindole (TROX-1), a state-dependent, voltage-gated calcium channel 2 blocker.
    The Journal of pharmacology and experimental therapeutics, 2010, Volume: 334, Issue:2

    Topics: Analgesics; Animals; Baroreflex; Biological Availability; Calcium Channel Blockers; Calcium Channels, N-Type; Calcium Channels, R-Type; Cation Transport Proteins; Cell Line; Dogs; Ganglia, Spinal; Hyperalgesia; Hypotension, Orthostatic; Indoles; Male; Mice; Mice, Knockout; Neurons; Pain; Patch-Clamp Techniques; Rats; Rats, Sprague-Dawley; Triazoles

2010
Characterization of the substituted N-triazole oxindole TROX-1, a small-molecule, state-dependent inhibitor of Ca(V)2 calcium channels.
    Molecular pharmacology, 2012, Volume: 81, Issue:3

    Topics: Calcium Channel Blockers; Calcium Channels, N-Type; Cell Line; Humans; Indoles; Inhibitory Concentration 50; Membrane Potentials; Patch-Clamp Techniques; Triazoles

2012
An automated electrophysiological assay for differentiating Ca(v)2.2 inhibitors based on state dependence and kinetics.
    Assay and drug development technologies, 2012, Volume: 10, Issue:6

    Topics: Animals; Automation; Biological Assay; Calcium Channel Blockers; Calcium Channels, N-Type; Cell Line; Data Interpretation, Statistical; Drug Evaluation, Preclinical; Electrophysiology; Indoles; Kinetics; omega-Conotoxins; Patch-Clamp Techniques; Pyrimidines; Rats; Structure-Activity Relationship; Triazines; Triazoles

2012
Electrophysiological characterization of activation state-dependent Ca(v)2 channel antagonist TROX-1 in spinal nerve injured rats.
    Neuroscience, 2015, Jun-25, Volume: 297

    Topics: Acetone; Action Potentials; Animals; Calcium Channel Blockers; Disease Models, Animal; Dose-Response Relationship, Drug; Electric Stimulation; Ganglia, Spinal; Hyperalgesia; Indoles; Male; omega-Conotoxins; Pain Measurement; Pain Threshold; Patch-Clamp Techniques; Peripheral Nerve Injuries; Rats; Rats, Sprague-Dawley; Sensory Receptor Cells; Spinal Nerves; Triazoles

2015
Electrophysiological evidence for voltage-gated calcium channel 2 (Cav2) modulation of mechano- and thermosensitive spinal neuronal responses in a rat model of osteoarthritis.
    Neuroscience, 2015, Oct-01, Volume: 305

    Topics: Animals; Calcium Channel Blockers; Caveolin 2; Disease Models, Animal; Evoked Potentials; Functional Laterality; Hyperalgesia; Indoles; Iodoacetic Acid; Male; Neurons; omega-Conotoxins; Osteoarthritis; Pain Measurement; Rats; Rats, Sprague-Dawley; Transcutaneous Electric Nerve Stimulation; Triazoles

2015