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triazoles and 2-phenyl-6-(2'-(4'-(ethoxycarbonyl)thiazolyl))thiazolo(3,2-b)(1,2,4)triazole

triazoles has been researched along with 2-phenyl-6-(2'-(4'-(ethoxycarbonyl)thiazolyl))thiazolo(3,2-b)(1,2,4)triazole in 11 studies

Research

Studies (11)

TimeframeStudies, this research(%)All Research%
pre-19901 (9.09)18.7374
1990's2 (18.18)18.2507
2000's7 (63.64)29.6817
2010's1 (9.09)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Bernier, JL; Helbecque, N; Henichart, JP; Houssin, R1
Ahgren, C; Backro, K; Bell, FW; Cantrell, AS; Clemens, M; Colacino, JM; Deeter, JB; Engelhardt, JA; Hogberg, M; Jaskunas, SR1
Engelhardt, P; Högberg, M; Kangasmetsä, J; Noréen, R; Sahlberg, C; Vrang, L; Zhang, H1
Balzarini, J; Bird, LE; Diprose, J; Esnouf, RM; Ikemizu, S; Milton, J; Ren, J; Slater, M; Stammers, DK; Stuart, DI; Warren, J1
Mao, C; Sudbeck, EA; Uckun, FM; Venkatachalam, TK1
Mao, C; Uckun, FM; Venkatachalam, TK1
Auwerx, J; Balzarini, J; Bird, LE; De Clercq, E; Karlsson, A; Oberg, B; Ren, J; Stammers, DK; Stevens, M; Van Rompay, AR1
D'Cruz, OJ; Uckun, FM1
Agrawal, RK; Ravichandran, V1
Fassihi, A; Moeinifard, B; Sabet, R1
Hong, Y; Rugang, Z; Xiaohe, Z; Xiuqing, S; Yu, Q1

Reviews

2 review(s) available for triazoles and 2-phenyl-6-(2'-(4'-(ethoxycarbonyl)thiazolyl))thiazolo(3,2-b)(1,2,4)triazole

ArticleYear
Structure-based drug design of non-nucleoside inhibitors for wild-type and drug-resistant HIV reverse transcriptase.
    Biochemical pharmacology, 2000, Nov-01, Volume: 60, Issue:9

    Topics: Amino Acid Substitution; Drug Design; Drug Resistance, Microbial; HIV; HIV Reverse Transcriptase; Humans; Models, Molecular; Mutation; Reverse Transcriptase Inhibitors; Structure-Activity Relationship; Thiazoles; Triazoles

2000
Novel tight binding PETT, HEPT and DABO-based non-nucleoside inhibitors of HIV-1 reverse transcriptase.
    Journal of enzyme inhibition and medicinal chemistry, 2006, Volume: 21, Issue:4

    Topics: Acquired Immunodeficiency Syndrome; Anti-Retroviral Agents; Chemistry, Pharmaceutical; Drug Design; Drug Industry; HIV; HIV Reverse Transcriptase; Humans; Models, Chemical; Models, Molecular; Mutation; Pyrimidines; Reverse Transcriptase Inhibitors; Thiazoles; Thymine; Triazoles

2006

Other Studies

9 other study(ies) available for triazoles and 2-phenyl-6-(2'-(4'-(ethoxycarbonyl)thiazolyl))thiazolo(3,2-b)(1,2,4)triazole

ArticleYear
A new bithiazole derivative with intercalative properties.
    Journal of biomolecular structure & dynamics, 1986, Volume: 4, Issue:2

    Topics: Animals; Cattle; Chemical Phenomena; Chemistry; DNA; Hot Temperature; Intercalating Agents; Models, Molecular; Nucleic Acid Conformation; Nucleic Acid Denaturation; Thiazoles; Thymus Gland; Triazoles

1986
The PETT series, a new class of potent nonnucleoside inhibitors of human immunodeficiency virus type 1 reverse transcriptase.
    Antimicrobial agents and chemotherapy, 1995, Volume: 39, Issue:6

    Topics: Animals; Antiviral Agents; Base Sequence; Benzodiazepines; Brain; Cattle; Cells, Cultured; DNA-Directed DNA Polymerase; Drug Resistance, Microbial; HIV-1; Humans; Imidazoles; Intercalating Agents; Male; Molecular Sequence Data; Pyridines; Rats; Rats, Inbred F344; Reverse Transcriptase Inhibitors; Structure-Activity Relationship; Thiazoles; Thiourea; Triazoles

1995
Synthesis and anti-HIV activities of urea-PETT analogs belonging to a new class of potent non-nucleoside HIV-1 reverse transcriptase inhibitors.
    Bioorganic & medicinal chemistry letters, 1998, Jun-16, Volume: 8, Issue:12

    Topics: Anti-HIV Agents; Blood Proteins; Cell Line; HIV-1; Humans; Microbial Sensitivity Tests; Protein Binding; Reverse Transcriptase Inhibitors; Structure-Activity Relationship; Thiazoles; Triazoles

1998
Phenylethylthiazolylthiourea (PETT) non-nucleoside inhibitors of HIV-1 and HIV-2 reverse transcriptases. Structural and biochemical analyses.
    The Journal of biological chemistry, 2000, Feb-25, Volume: 275, Issue:8

    Topics: Binding, Competitive; Crystallography, X-Ray; Deoxyguanine Nucleotides; DNA Primers; Dose-Response Relationship, Drug; HIV Reverse Transcriptase; Inhibitory Concentration 50; Intercalating Agents; Kinetics; Models, Chemical; Models, Molecular; Protein Binding; Pyridines; Regression Analysis; Reverse Transcriptase Inhibitors; RNA-Directed DNA Polymerase; Thiazoles; Thiourea; Triazoles

2000
Effect of stereo and regiochemistry towards wild and multidrug resistant HIV-1 virus: viral potency of chiral PETT derivatives.
    Biochemical pharmacology, 2004, May-15, Volume: 67, Issue:10

    Topics: Anti-HIV Agents; Drug Resistance, Multiple; Drug Stability; HIV-1; Humans; Microbial Sensitivity Tests; Models, Molecular; Molecular Conformation; Stereoisomerism; Structure-Activity Relationship; Thiazoles; Triazoles

2004
The phenylmethylthiazolylthiourea nonnucleoside reverse transcriptase (RT) inhibitor MSK-076 selects for a resistance mutation in the active site of human immunodeficiency virus type 2 RT.
    Journal of virology, 2004, Volume: 78, Issue:14

    Topics: Amino Acid Sequence; Anti-HIV Agents; Cells, Cultured; Cytopathogenic Effect, Viral; Drug Resistance, Viral; HIV Reverse Transcriptase; HIV-1; HIV-2; Humans; Microbial Sensitivity Tests; Models, Molecular; Molecular Sequence Data; Mutation; Reverse Transcriptase Inhibitors; RNA-Directed DNA Polymerase; Thiazoles; Triazoles

2004
Predicting anti-HIV activity of PETT derivatives: CoMFA approach.
    Bioorganic & medicinal chemistry letters, 2007, Apr-15, Volume: 17, Issue:8

    Topics: Anti-HIV Agents; Computational Biology; Drug Design; Humans; Models, Molecular; Quantitative Structure-Activity Relationship; Reverse Transcriptase Inhibitors; Static Electricity; Thiazoles; Thiourea; Triazoles

2007
QSAR study of PETT derivatives as potent HIV-1 reverse transcriptase inhibitors.
    Journal of molecular graphics & modelling, 2009, Volume: 28, Issue:2

    Topics: Enzyme Inhibitors; HIV Reverse Transcriptase; Models, Molecular; Molecular Structure; Quantitative Structure-Activity Relationship; Thiazoles; Triazoles

2009
Synthesis, biological evaluation and molecular modeling studies of N-aryl-2-arylthioacetamides as non-nucleoside HIV-1 reverse transcriptase inhibitors.
    Chemical biology & drug design, 2010, Volume: 76, Issue:4

    Topics: Binding Sites; Cell Line; Computer Simulation; HIV Reverse Transcriptase; HIV-1; Humans; Imidazoles; Models, Molecular; Protein Binding; Protein Structure, Tertiary; Reverse Transcriptase Inhibitors; Thiazoles; Thioacetamide; Triazoles

2010