triazoles has been researched along with 2-(4-(2-carboxyethyl)phenethylamino)-5'-n-ethylcarboxamidoadenosine in 167 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 36 (21.56) | 18.2507 |
| 2000's | 87 (52.10) | 29.6817 |
| 2010's | 44 (26.35) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Barraco, RA; Phillis, JW | 1 |
| Amoroso, S; Annunziato, L; Di Renzo, G; Iannotti, E; Saggese, ML | 1 |
| Borchard, U; Felsch, A; Stöcker, K | 1 |
| Patel, M; Sheehan, MJ; Strong, P | 1 |
| Schmitz, W; Scholz, H; Seeland, C; Stein, B | 1 |
| Ahlberg, S; Fredholm, BB; Olsson, RA; Parkinson, FE; van der Ploeg, I | 1 |
| Hourani, SM; Prentice, DJ | 2 |
| Anderson, GF; Barraco, RA; Helfman, CC | 1 |
| Fredholm, BB; Lindström, K; Ongini, E | 1 |
| Dixon, AK; Richardson, PJ; Widdowson, L | 1 |
| Cristalli, G; Morelli, M; Pinna, A; Wardas, J | 1 |
| Apasov, S; Huang, S; Kojima, H; Koshiba, M; Sitkovsky, MV | 1 |
| Alexander, SP; Cooper, J; Hill, SJ | 1 |
| Constantino, MD; Cunha, RA; Ribeiro, JA | 2 |
| Fukamachi, H; Nakahata, T; Suzuki, H; Takei, M | 1 |
| Dionisotti, S; Fredholm, BB; Lindström, K; Ongini, E | 1 |
| Belardinelli, L; Dennis, DM; Lozza, G; Monopoli, A; Olsson, RA; Ongini, E; Shryock, JC; Snowdy, S; Zhang, Y | 1 |
| Betti, L; Biagi, G; Giannaccini, G; Giorgi, I; Livi, O; Lucacchini, A; Manera, C; Scartoni, V | 1 |
| Biaggioni, I; Feoktistov, I | 1 |
| Coney, AM; Marshall, JM | 1 |
| Jones, PA; Smith, RA; Stone, TW | 2 |
| Baker, SP; Baraldi, PG; Belardinelli, L; Cacciari, B; Monopoli, A; Ongini, E; Shryock, JC; Snowdy, S; Spalluto, G | 1 |
| Bryan, PT; Marshall, JM | 1 |
| O'Kane, EM; Stone, TW | 1 |
| Cutler, BS; Dobson, JG; Fenton, RA; Li, Jm; Peyton, BD; Powell, CC; Wheeler, HB | 1 |
| Arslan, G; Fredholm, BB; Kull, B; Lorenzen, A; Nilsson, C; Owman, C; Schwabe, U | 1 |
| Cseppentö, A; Kovács, P; Nagy, E; Szabó, JZ; Szentmiklósi, AJ; Ujfalusi, A | 1 |
| Cunha, RA; Lopes, LV; Ribeiro, JA | 2 |
| Fredholm, BB; Lindström, K | 1 |
| Bordoni, F; Corradetti, R; Latini, S; Pedata, F; Pepeu, G | 1 |
| Davie, CS; Everitt, DE; Standen, NB | 1 |
| Borgeat, P; Bourgoin, SG; Harbour, D; Naccache, PH; Thibault, N | 1 |
| Costentin, J; El Yacoubi, M; Ledent, C; Parmentier, M; Vaugeois, JM | 1 |
| Abebe, W; Arif Hasan, AZ; Mustafa, SJ | 1 |
| Jabbari-T, J; Oberhauser, V; Rump, LC; von Kügelgen, I | 1 |
| Albrizio, S; D'Ursi, A; Galoppini, C; Giusti, L; Greco, G; Hamm, HE; Lucacchini, A; Mazzoni, MR; Novellino, E; Rovero, P; Taddei, S; Triolo, A | 1 |
| Anderson, R; Ramafi, G; Theron, AJ; Visser, SS | 1 |
| Olah, ME; Roudabush, FL | 1 |
| Costentin, J; El Yacoubi, M; Ledent, C; Parmentier, M; Vaugeois, J | 1 |
| Feoktistov, I; Mustafa, SJ; Olanrewaju, HA; Qin, W; Scemama, JL | 1 |
| Harada, N; Katsuragi, T; Murakami, K; Ohshima, K; Okajima, K; Sato, C; Usune, S | 1 |
| Koos, BJ; Maeda, T | 1 |
| Hein, TW; Kuo, L; Muthuchamy, M; Wang, W; Zoghi, B | 1 |
| Coyne, EF; Meno, JR; Ngai, AC; West, GA; Winn, HR | 1 |
| Baker, SP; Belardinelli, L; Blackburn, B; Elzein, E; Gao, Z; Lasley, RD; Li, Z; Meyer, S; Palle, V; Zablocki, JA | 1 |
| Nikbakht, MR; Stone, TW | 1 |
| Hamann, M; Richter, A | 1 |
| Brookins, J; Fisher, JW | 1 |
| Breschi, MC; Calderone, V; Martinotti, E; Nieri, P | 1 |
| Harvey, V; Jones, J; Knight, AR; Misra, A; Quirk, K | 1 |
| Furue, H; Kumamoto, E; Lao, LJ; Luo, C; Yoshimura, M | 1 |
| Ashton, K; Berr, SS; Cerniway, RJ; Harrison, GJ; Headrick, JP; Paul Matherne, G; Peart, J; Regan, S | 1 |
| Ellis, KM; Fozard, JR; Mazzoni, L; Tigani, B; Villela Dantas, MF | 1 |
| Jacobson, KA; Jacobson, MA; Ledent, C; Morrison, RR; Mustafa, SJ; Talukder, MA | 1 |
| Bonfanti, A; Marchi, M; Monopoli, A; Ongini, E; Raiteri, L; Raiteri, M; Risso, F; Vallarino, A | 1 |
| Cunha, RA; Fredholm, BB; Kull, B; Lopes, LV; Ribeiro, JA | 1 |
| Belem, PC; Chen, JF; Cronstein, B; Elson, G; Fink, JS; Jacobson, M; Leibovich, SJ; Montesinos, C; Pinhal-Enfield, G; Ramanathan, M; Rosania, A; Schwarzschild, MA | 1 |
| Gao, ZG; IJzerman, AP; Jacobson, KA; Kim, SG; Melman, N; Soltysiak, KA | 1 |
| Bril, A; Broadley, KJ; Khandoudi, N; Maddock, HL | 1 |
| Bibb, JA; Fienberg, AA; Fisone, G; Fredholm, BB; Greengard, P; Kim, Y; Lindskog, M; Nairn, AC; Pozzi, L; Svenningsson, P | 1 |
| Ezeamuzie, CI; Philips, E | 1 |
| Diniz, C; Gonçalves, J; Leal, S | 1 |
| Antoniou, K; Ferré, S; Fuxe, K; Goldberg, SR; Justinova, Z; Karcz-Kubicha, M; Müller, CE; Pezzola, A; Popoli, P; Quarta, D; Reggio, R; Solinas, M; Terasmaa, A | 1 |
| Hague, BF; Kindt, TJ; Zhao, TM | 1 |
| Boehm, S; Freissmuth, M; Just, H; Klinger, M; Korkhov, VM; Kudlacek, O; Nanoff, C; Pankevych, H; Vartian, N; Yang, Q | 1 |
| Abbracchio, MP; Brambilla, R; Ceruti, S; Cottini, L; Fumagalli, M | 1 |
| Fredholm, BB; Hellsten, Y; Lynge, J; Nordsborg, N; Schulte, G | 1 |
| Cunha, RA; de Mendonca, A; Oliveira, CR; Rebola, N; Ribeiro, JA; Sebastião, AM | 1 |
| Benwell, K; Cliffe, IA; Dourish, CT; Gillespie, RJ; Knight, AR; Lerpiniere, J; Misra, A; Pratt, RM; Revell, D; Upton, R; Weiss, SM | 1 |
| Brooke, RE; Deuchars, J; Deuchars, SA | 1 |
| Kwok, YN; Yip, L | 1 |
| Catarzi, D; Colotta, V; Filacchioni, G; Lucacchini, A; Martini, C; Trincavelli, L; Varano, F | 1 |
| Chen, JF; Cunha, RA; Fredholm, BB; Halldner, L; Johansson, B; Ledent, C; Lopes, LV; Rebola, N | 1 |
| Diógenes, MJ; Fernandes, CC; Ribeiro, JA; Sebastião, AM | 1 |
| Awadallah, NW; Chan, ES; Cronstein, BN; Montesinos, MC; Rahman, MM; Reiss, AB | 1 |
| Domenici, MR; Frank, C; Grieco, R; Martire, A; Pepponi, R; Pintor, A; Popoli, P; Potenza, RL; Tebano, MT | 1 |
| Diniz, C; Fresco, P; Gonçalves, J | 1 |
| Domenici, MR; Martire, A; Pepponi, R; Popoli, P; Potenza, RL; Tebano, MT | 1 |
| Abbracchio, MP; Ceruti, S; Marroni, M; Martini, C; Mazzola, A; Mitro, N; Trincavelli, ML; Tuscano, D | 1 |
| Alfaro, TM; Cunha, RA; Oliveira, CR; Rebola, N; Rodrigues, RJ | 1 |
| Fuxe, K; Rinken, A; Terasmaa, A; Uustare, A; Vonk, A | 1 |
| Abbracchio, MP; Camurri, A; Capecchi, PL; Diciolla, F; Laghi-Pasini, F; Lazzerini, PE; Maccherini, M; Mazzola, A; Pompella, G | 1 |
| Bonan, CD; Cammarota, M; Izquierdo, I; Pereira, GS; Rossato, JI; Sarkis, JJ | 1 |
| Arun, KH; Kaul, CL; Kumar, S; Sharma, SS | 1 |
| Angulo, E; Casadó, V; Chen, JF; Ejarque, A; Franco, R; Lluis, C; Moratalla, R; Saura, J; Schwarzschild, MA; Serratosa, J; Tusell, JM | 1 |
| Fathollahi, Y; Mirnajafi-Zadeh, J; Namvar, S; Rezvani, ME; Zeraati, M | 1 |
| Antonioli, L; Blandizzi, C; Colucci, R; Del Tacca, M; Fornai, M; Ghisu, N | 1 |
| Baghdoyan, HA; Coleman, CG; Lydic, R | 1 |
| Aceves, J; Erlij, D; Florán, B; Florán, L; Gonzalez, B; Paz, F | 1 |
| Greengard, P; Higashi, H; Kuroiwa, M; Nishi, A; Shuto, T; Snyder, GL; Sotogaku, N; Tanaka, M; Yabuuchi, K | 1 |
| Chuaychoo, B; Kollarik, M; Lee, MG; Pullmann, R; Undem, BJ | 1 |
| Brown, R; Fredholm, BB; Lai, EY; Mrowka, R; Patzak, A; Persson, AE; Persson, PB; Spielmann, N; Steege, A | 1 |
| Huxley, VH; Wang, J | 1 |
| Gomes, CA; Ribeiro, JA; Sebastião, AM; Vaz, SH | 1 |
| Grden, M; Kocbuch, K; Pawelczyk, T; Podgorska, M; Szutowicz, A | 1 |
| Gao, C; Gao, N; Hu, HZ; Liu, S; Wood, JD; Xia, Y | 1 |
| Belardinelli, L; Chu, N; Diamond, I; Kalla, R; Leung, K; Shryock, JC; Soelaiman, S; Soohoo, D; Yang, M; Yao, L; Zablocki, J | 1 |
| Biskup, W; Celiński, K; Cichoz-Lach, H; Czechowska, G; Korobowicz, E; Korolczuk, A; Madro, A; Prozorow-Król, B; Słomka, M | 1 |
| Bradding, P; Brightling, CE; Cruse, G; Duffy, SM | 1 |
| Fathollahi, Y; Hosseinmardi, N; Mirnajafi-Zadeh, J; Shahabi, P | 1 |
| Fathollahi, Y; Mirnajafi-Zadeh, J; Palizvan, MR; Rezvani, ME | 1 |
| Baranyi, M; Illes, P; Sperlágh, B; Vizi, ES; Zsilla, G | 1 |
| Belcastro, V; Borsini, F; Calabresi, P; Centonze, D; Costa, C; Picconi, B; Tantucci, M; Tozzi, A; Tscherter, A | 1 |
| Cao, Z; Hurley, DJ; Linden, J; Moore, JN; Murray, TF; Sun, WC; Vandenplas, ML | 1 |
| Desfrere, L; Gressens, P; Olivier, P; Schwendimann, L; Verney, C | 1 |
| Cunha, RA; Lujan, R; Mulle, C; Rebola, N | 1 |
| Diógenes, MJ; Fontinha, BM; Ribeiro, JA; Sebastião, AM | 1 |
| Casanello, P; Escudero, C; Sobrevia, L | 1 |
| Ansari, HR; Falck, JR; Ledent, C; Mustafa, SJ; Nayeem, MA; Poloyac, SM; Ponnoth, DS; Zeldin, DC | 1 |
| Bendor, J; Flajolet, M; Futter, M; Greengard, P; Nairn, AC; Nuangchamnong, N; Shen, W; Surmeier, DJ; Wallach, I; Wang, Z | 1 |
| Hamilton, JB; Lancaster, DM; Patel, N; Pietersen, AN; Vreugdenhil, M | 1 |
| Baghdoyan, HA; Lydic, R; Van Dort, CJ | 1 |
| Ichinose, TK; O'Leary, DS; Scislo, TJ | 1 |
| Church, JE; Coupar, IM; Pouton, CW; Rose'Meyer, RB; Urmaliya, VB; White, PJ | 1 |
| Cipriani, S; Galli, A; Gianfriddo, M; Giovannini, MG; Mello, T; Pedata, F; Pugliese, AM; Traini, C | 1 |
| Csóka, B; Haskó, G; Leibovich, SJ; Lukashev, D; Luo, W; Ramanathan, M; Sitkovsky, MV | 1 |
| Batchelor, DV; Chavaroche, H; Lemaitre, A; Macintyre, F; Mantell, SJ; Maw, GN; Monaghan, SM; Rozze, S; Selby, MD; Stephenson, PT; Stuart, EF; Trevethick, MA; Walker, DK; Whitlock, L; Wright, KN; Wright, PA; Yeadon, M | 1 |
| Ballerini, P; Biagioni, F; Buccella, S; Caciagli, F; Ciccarelli, R; Citraro, R; D'Alimonte, I; D'Auro, M; De Sarro, G; Di Iorio, P; Giuliani, P; Jiang, S; Nargi, E; Russo, E | 1 |
| Krahn, T; Ledent, C; Mustafa, SJ; Ponnoth, DS; Roush, K; Sanjani, MS | 1 |
| Aronhime, SN; Chen, JF; Echeverry, G; Kulik, TB; Kusano, Y; Miekisiak, G; Winn, HR | 1 |
| Devaux, Y; Ernens, I; Léonard, F; Rolland-Turner, M; Vausort, M; Wagner, DR | 1 |
| Cairo, G; Gammella, E; Tacchini, L | 1 |
| Bouïs, D; Changelian, PS; Harada, H; Lama, VN; Noon, K; Ohtsuka, T; Pinsky, DJ | 1 |
| Li, GQ; Lu, HH; Mo, Q; Qian, J; Tang, LM; Wang, F; Wang, XH; Zhu, J; Zhu, JF | 1 |
| Fredholm, BB; Hao, JX; Li, L; Schulte, G; Wiesenfeld-Hallin, Z; Xu, XJ | 1 |
| Barodia, SK; Kumari, N; Luthra, PM; Mishra, CB; Prakash, A; Senthil Kumar, JB | 1 |
| Berwick, ZC; Dick, GM; Lynch, B; Payne, GA; Sturek, M; Tune, JD | 1 |
| Che, PL; Du, J; Ha, B; Wang, Z; Yarema, KJ | 1 |
| Bramanti, P; Cipriani, S; Corti, F; Cuzzocrea, S; Esposito, E; Mazzon, E; Melani, A; Mello, T; Paterniti, I; Pedata, F | 1 |
| Chen, JF; Feng, L; Garcia, GE; Johnson, RJ; Truong, LD | 1 |
| Cronstein, BN; Williams, AJ | 1 |
| Biragyn, A; Ferrucci, L; Goetzl, EJ; Hesdorffer, CS; Kennedy, RT; Longo, DL; Mabrouk, OS; Madara, K; Malchinkhuu, E; Schwartz, JB; Taub, DD | 1 |
| Falck, JR; Morisseau, C; Mustafa, SJ; Nayeem, MA; Pradhan, I; Zeldin, DC | 1 |
| Ailawadi, G; Barbery, C; Bhamidipati, CM; Kron, IL; Laubach, VE; Meher, AK; Mehta, GS; Moehle, CW; Owens, GK; Sharma, AK; Su, G; Upchurch, GR; Vigneshwar, NG | 1 |
| An, JH; Chen, JF; Dai, SS; Li, W; Ning, YL; Wang, H; Yang, N; Zhou, YG; Zhu, PF | 1 |
| Ding, X; Li, T; Liu, L; Peng, X; Yang, G; Zhu, Y | 1 |
| Alam, MN; Hsieh, KC; Kumar, S; McGinty, D; Rai, S; Szymusiak, R | 1 |
| Agostinho, P; Castro, AA; Cunha, RA; Garção, P; Köfalvi, A; Prediger, RD; Szabó, EC; Tomé, ÂR; Wopereis, S | 1 |
| Cellai, L; Coppi, E; Maraula, G; Pedata, F; Pugliese, AM | 1 |
| Carter, EL; Heitmiller, KD; Hong, G; Jamrogowicz, JL; Koehler, RC; Kwansa, H; Larson, AC; Martin, LJ; Wang, B; Yang, ZJ | 1 |
| Bernardo, A; De Nuccio, C; Ferrante, A; Minghetti, L; Pepponi, R; Popoli, P; Visentin, S | 1 |
| Minic, Z; O'Leary, DS; Scislo, TJ | 1 |
| Boiko, N; Chimote, AA; Conforti, L; Hajdu, P; Kucher, V; Kuras, Z; Szilagyi, O; Yun, YH | 1 |
| Agostinho, P; Augusto, E; Chen, JF; Cunha, RA; Matos, M | 1 |
| Frøbert, O; Hedegaard, ER; Mogensen, S; Nielsen, BD; Rembold, CM; Simonsen, U | 1 |
| Diógenes, MJ; Jerónimo-Santos, A; Rodrigues, TM; Sebastião, AM | 1 |
| Exley, M; Kini, R; Madasu, M; Nowak, M; Ohta, A; Sitkovsky, M; Subramanian, M | 1 |
| Arias-Montaño, JA; Escamilla-Sánchez, J; González-Pantoja, R; Márquez-Gómez, R; Morales-Figueroa, GE | 1 |
| Filip, M; Fuxe, K; Gołembiowska, K; Kamińska, K; Suder, A; Wydra, K | 1 |
| Cataño-Cañizalez, YG; Cortés-Garcia, JD; Cortez-Espinosa, N; Guzman-Flores, JM; Portales-Perez, DP; Rodríguez-Rivera, JG; Vargas-Morales, JM | 1 |
| Almeida, AS; Botton, PH; Chenet, GC; Cunha, RA; Loss, CM; Marques, DM; Mioranzza, S; Nunes, F; Pagnussat, N; Porciúncula, LO | 1 |
| Hiromura, M; Honda, S; Inoue, K; Kosako, K; Kuroki, H; Shiratani, T; Soeda, S; Toda, A; Uchiyama, H | 1 |
| Cortés-Garcia, JD; Cortez-Espinosa, N; García-Hernández, MH; Guzmán-Flores, JM; Layseca-Espinosa, E; López-López, C; Portales-Cervantes, L; Portales-Pérez, DP | 1 |
| Diógenes, MJ; Lérias, SR; Parreira, S; Sebastião, AM; Vaz, SH | 1 |
| Brozmanova, M; Hu, Y; Kollarik, M; Mazurova, L; Ru, F; Tatar, M; Yu, S | 1 |
| Cherasse, Y; de Kerchove d'Exaerde, A; Huang, ZL; Lavielle, O; Lazarus, M; Li, R; McEown, K; Qu, WM; Schiffmann, SN; Wang, DR; Wang, YQ; Zhang, MQ; Zhang, Z | 1 |
| Bai, W; Chen, JF; Chen, X; Chen, XY; Li, P; Liu, D; Ning, YL; Peng, Y; Wang, H; Yang, N; Zhao, Y; Zhao, ZA; Zhou, YG | 1 |
| Fischer, L; Morais, RN; Sardi, NF; Tobaldini, G | 1 |
| Chen, L; Duan, W; Fan, Q; Huang, H; Ran, H; Wang, H | 1 |
| Cao, J; Dong, Z; Li, W; Lin, H; Shi, Y; Xiao, R; Zhang, X | 1 |
| Babu, KS; Murthy, M; Velayutham, P | 1 |
| Cai, H; Cai, X; Chen, L; Chen, X; Han, X; Shi, H; Singh, BL; Wang, Y; Yu, C | 1 |
| Gom, RC; Phillips, TJ; Teskey, GC; Wolff, MD | 1 |
1 trial(s) available for triazoles and 2-(4-(2-carboxyethyl)phenethylamino)-5'-n-ethylcarboxamidoadenosine
| Article | Year |
|---|---|
Plasma glutamate-modulated interaction of A2AR and mGluR5 on BMDCs aggravates traumatic brain injury-induced acute lung injury.
Topics: Acute Lung Injury; Adenosine; Adenosine A2 Receptor Agonists; Adult; Animals; Bone Marrow Cells; Brain Injuries; Disease Models, Animal; Female; Glutamic Acid; Humans; Male; Mice; Mice, Knockout; Middle Aged; Phenethylamines; Protein Kinase C; Receptor, Adenosine A2A; Receptor, Metabotropic Glutamate 5; Receptors, Metabotropic Glutamate; Signal Transduction; Triazines; Triazoles; Type C Phospholipases | 2013 |
166 other study(ies) available for triazoles and 2-(4-(2-carboxyethyl)phenethylamino)-5'-n-ethylcarboxamidoadenosine
| Article | Year |
|---|---|
Subtypes of adenosine receptors in the brainstem mediate opposite blood pressure responses.
Topics: Adenosine; Animals; Antihypertensive Agents; Blood Pressure; Brain Stem; Dose-Response Relationship, Drug; Male; Phenethylamines; Quinazolines; Rats; Rats, Inbred Strains; Receptors, Purinergic; Triazoles; Xanthines | 1991 |
The A1 agonist CCPA reduced bisoxonol-monitored membrane potential depolarization elicited by high K+ in cerebrocortical nerve endings.
Topics: Adenosine; Animals; Cerebral Cortex; Fluorescent Dyes; Male; Membrane Potentials; Nerve Endings; Phenethylamines; Potassium; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Quinazolines; Rats; Rats, Wistar; Synaptosomes; Thiobarbiturates; Triazoles; Veratridine; Xanthines | 1995 |
Adenosine A1 and A2 receptor agonists alter cardiac functions and prostacyclin release in the isolated guinea-pig heart.
Topics: 6-Ketoprostaglandin F1 alpha; Adenosine; Animals; Antihypertensive Agents; Cardiac Pacing, Artificial; Cells, Cultured; Coronary Circulation; Dose-Response Relationship, Drug; Endothelium, Vascular; Epoprostenol; Guinea Pigs; Heart; Heart Rate; Male; Myocardium; Phenethylamines; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Quinazolines; Triazoles; Vasodilation; Ventricular Function, Left; Xanthines | 1994 |
Failure of CGS15943A to block the hypotensive action of agonists acting at the adenosine A3 receptor.
Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Blood Pressure; Female; Phenethylamines; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Quinazolines; Rats; Rats, Wistar; Triazoles | 1994 |
Pharmacological characterization of A2-adenosine receptors in guinea-pig ventricular cardiomyocytes.
Topics: Adenosine; Adenylate Cyclase Toxin; Adenylyl Cyclases; Animals; Cells, Cultured; Cyclic AMP; Drug Interactions; Female; Guinea Pigs; Heart Ventricles; Isoproterenol; Male; Myocardial Contraction; Myocardium; Papillary Muscles; Pertussis Toxin; Phenethylamines; Quinazolines; Receptors, Adrenergic, beta; Receptors, Purinergic P1; Signal Transduction; Triazoles; Virulence Factors, Bordetella; Xanthines | 1994 |
Functional characterization of adenosine A2 receptors in Jurkat cells and PC12 cells using adenosine receptor agonists.
Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Amino Acid Sequence; Animals; Base Sequence; Binding, Competitive; Colforsin; Cyclic AMP; DNA; Humans; Isotope Labeling; Lethal Dose 50; Leukemia, T-Cell; Molecular Sequence Data; PC12 Cells; Phenethylamines; Polymerase Chain Reaction; Purinergic P1 Receptor Agonists; Quinazolines; Rats; Receptors, Purinergic P1; RNA, Messenger; Triazoles; Tumor Cells, Cultured | 1996 |
Activation of multiple sites by adenosine analogues in the rat isolated aorta.
Topics: Adenosine; Animals; Aorta, Thoracic; Endothelium, Vascular; Enzyme Inhibitors; In Vitro Techniques; Male; Muscle Relaxation; Muscle, Smooth, Vascular; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Phenethylamines; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Purines; Rats; Rats, Wistar; Receptors, Purinergic P1; Sulfonamides; Theophylline; Triazines; Triazoles; Xanthines | 1996 |
Augmented release of serotonin by adenosine A2a receptor activation and desensitization by CGS 21680 in the rat nucleus tractus solitarius.
Topics: Adenosine; Animals; In Vitro Techniques; Kinetics; Male; Phenethylamines; Purinergic P1 Receptor Agonists; Quinazolines; Rats; Rats, Sprague-Dawley; Receptors, Purinergic P1; Serotonin; Solitary Nucleus; Triazoles; Xanthines | 1996 |
The selective adenosine A2A receptor antagonist SCH 58261 discriminates between two different binding sites for [3H]-CGS 21680 in the rat brain.
Topics: Adenosine; Animals; Autoradiography; Binding, Competitive; Brain; Cerebral Cortex; Corpus Striatum; Hippocampus; Phenethylamines; Protein Binding; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Pyrimidines; Rats; Triazoles; Tritium | 1996 |
Adenosine analogues relax guinea-pig taenia caeci via an adenosine A2B receptor and a xanthine-resistant site.
Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Cecum; Dose-Response Relationship, Drug; Guinea Pigs; Male; Muscle Relaxation; Muscle, Smooth; Phenethylamines; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Theophylline; Triazines; Triazoles; Vasodilator Agents; Xanthines | 1997 |
Desensitisation of the adenosine A1 receptor by the A2A receptor in the rat striatum.
Topics: Adenosine; Animals; Antihypertensive Agents; Corpus Striatum; Enzyme Inhibitors; Isoquinolines; Phenethylamines; Presynaptic Terminals; Protein Kinase C; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Rats; Rats, Wistar; Receptor, Adenosine A2A; Receptors, Purinergic P1; Sensitivity and Specificity; Sulfonamides; Synaptosomes; Triazines; Triazoles; Tritium; Xanthines | 1997 |
Adenosine A2A receptor agonists increase Fos-like immunoreactivity in mesolimbic areas.
Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Dopamine Agonists; Immunohistochemistry; Limbic System; Male; Oxidopamine; Phenethylamines; Proto-Oncogene Proteins c-fos; Purinergic Antagonists; Purinergic P1 Receptor Agonists; Pyrimidines; Quinpirole; Rats; Rats, Sprague-Dawley; Triazoles | 1997 |
Memory of extracellular adenosine A2A purinergic receptor-mediated signaling in murine T cells.
Topics: Adenosine; Animals; Cell Division; Exocytosis; Extracellular Matrix; Fas Ligand Protein; fas Receptor; Interleukin-2; Membrane Glycoproteins; Mice; Mice, Inbred DBA; Phenethylamines; Purinergic P1 Receptor Agonists; Receptor, Adenosine A2A; Receptors, Antigen, T-Cell; Receptors, Purinergic P1; Signal Transduction; T-Lymphocytes; Triazines; Triazoles | 1997 |
An endogenous A2B adenosine receptor coupled to cyclic AMP generation in human embryonic kidney (HEK 293) cells.
Topics: 2-Chloroadenosine; Adenosine; Adenosine-5'-(N-ethylcarboxamide); Cells, Cultured; Cyclic AMP; DNA, Complementary; Gene Amplification; Humans; In Vitro Techniques; Kidney; Phenethylamines; Polymerase Chain Reaction; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Quinazolines; Receptor, Adenosine A2B; Receptors, Purinergic P1; Triazoles | 1997 |
ZM241385 is an antagonist of the facilitatory responses produced by the A2A adenosine receptor agonists CGS21680 and HENECA in the rat hippocampus.
Topics: Acetylcholine; Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Antihypertensive Agents; Binding Sites; Hippocampus; Ligands; Membranes; Phenethylamines; Platelet Aggregation Inhibitors; Purinergic P1 Receptor Agonists; Rats; Synaptic Transmission; Synaptosomes; Triazines; Triazoles; Visual Cortex | 1997 |
Inhibitory effect of adenosine on degranulation of human cultured mast cells upon cross-linking of Fc epsilon RI.
Topics: Adenosine; Antibodies; Chymases; Cross-Linking Reagents; Cyclic AMP; Guanosine; Humans; Immunoglobulin E; Mast Cells; Mitogen-Activated Protein Kinase 1; Phenethylamines; Phosphorylation; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Receptors, IgE; RNA, Messenger; Serine Endopeptidases; Thioinosine; Thionucleosides; Triazines; Triazoles; Tryptases | 1998 |
[3H]SCH 58261, a selective adenosine A2A receptor antagonist, is a useful ligand in autoradiographic studies.
Topics: Adenosine; Animals; Antihypertensive Agents; Autoradiography; Binding, Competitive; GTP-Binding Proteins; Guanosine Triphosphate; Ligands; Magnesium; Male; Phenethylamines; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Pyrimidines; Radioligand Assay; Rats; Rats, Sprague-Dawley; Receptor, Adenosine A2A; Triazoles; Tritium | 1998 |
The A2A adenosine receptor mediates coronary vasodilation.
Topics: Adenosine; Animals; Coronary Vessels; Female; Guinea Pigs; Male; Perfusion; Phenethylamines; Piperazines; Pyrimidines; Receptors, Purinergic P1; Triazoles; Tubercidin; Vasodilation; Xanthines | 1998 |
Novel 3-aralkyl-7-(amino-substituted)-1,2,3-triazolo[4,5-d]pyrimidines with high affinity toward A1 adenosine receptors.
Topics: Adenosine; Animals; Brain; Cattle; Cell Membrane; Cerebral Cortex; Corpus Striatum; Phenethylamines; Pyridazines; Pyrimidines; Radioligand Assay; Receptor, Adenosine A2A; Receptors, Purinergic P1; Stereoisomerism; Structure-Activity Relationship; Triazoles | 1998 |
Pharmacological characterization of adenosine A2B receptors: studies in human mast cells co-expressing A2A and A2B adenosine receptor subtypes.
Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Calcium; Cyclic AMP; Dose-Response Relationship, Drug; Humans; Mast Cells; Phenethylamines; Pyrimidines; Receptors, Purinergic P1; Triazoles; Tumor Cells, Cultured | 1998 |
Role of adenosine and its receptors in the vasodilatation induced in the cerebral cortex of the rat by systemic hypoxia.
Topics: Adenosine; Animals; Blood Flow Velocity; Blood-Brain Barrier; Erythrocytes; Hypoxia; Laser-Doppler Flowmetry; Male; Parietal Lobe; Phenethylamines; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Rats; Rats, Wistar; Receptors, Purinergic P1; Theophylline; Triazines; Triazoles; Vasodilation | 1998 |
Protection against kainate-induced excitotoxicity by adenosine A2A receptor agonists and antagonists.
Topics: Adenosine; Animals; Excitatory Amino Acid Agonists; Hippocampus; Kainic Acid; Male; Neurons; Neuroprotective Agents; Phenethylamines; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Rats; Rats, Wistar; Triazines; Triazoles; Xanthines | 1998 |
Protection against hippocampal kainate excitotoxicity by intracerebral administration of an adenosine A2A receptor antagonist.
Topics: Adenosine; Adrenergic alpha-2 Receptor Antagonists; Animals; Antihypertensive Agents; Brain Chemistry; Dose-Response Relationship, Drug; Excitatory Amino Acid Agonists; Hippocampus; Kainic Acid; Male; Neurotoxins; Phenethylamines; Rats; Rats, Wistar; Triazines; Triazoles | 1998 |
A2A-adenosine receptor reserve for coronary vasodilation.
Topics: Adenosine; Animals; Coronary Circulation; Female; Guinea Pigs; Heart; In Vitro Techniques; Kinetics; Male; Phenethylamines; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Pyrimidines; Receptor, Adenosine A2A; Receptors, Purinergic P1; Triazines; Triazoles; Vasodilation | 1998 |
Adenosine receptor subtypes and vasodilatation in rat skeletal muscle during systemic hypoxia: a role for A1 receptors.
Topics: Adenosine; Animals; Antihypertensive Agents; Blood Gas Analysis; Hydrogen-Ion Concentration; Hypoxia; Male; Muscle, Skeletal; Phenethylamines; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Rats; Rats, Wistar; Receptors, Purinergic P1; Regional Blood Flow; Respiration; Triazines; Triazoles; Vasodilation; Vasodilator Agents; Xanthines | 1999 |
Interaction between adenosine A1 and A2 receptor-mediated responses in the rat hippocampus in vitro.
Topics: Adenosine; Animals; Excitatory Postsynaptic Potentials; Hippocampus; Male; Organ Culture Techniques; Phenethylamines; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Pyrazines; Rats; Rats, Wistar; Receptors, Purinergic P1; Triazines; Triazoles | 1998 |
Adenosine A2a receptors increase arterial endothelial cell nitric oxide.
Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Carotid Arteries; Cells, Cultured; Endothelium, Vascular; Humans; Iliac Artery; Nitric Oxide; Phenethylamines; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Quinazolines; Receptor, Adenosine A2A; Receptors, Purinergic P1; Swine; Triazines; Triazoles; Xanthines | 1998 |
Differences in the order of potency for agonists but not antagonists at human and rat adenosine A2A receptors.
Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Binding, Competitive; CHO Cells; Cloning, Molecular; Cricetinae; Cyclic AMP; Humans; Kinetics; PC12 Cells; Phenethylamines; Polymerase Chain Reaction; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Pyrimidines; Radioligand Assay; Rats; Receptor, Adenosine A2A; Receptor, Adenosine A2B; Receptors, Purinergic P1; Recombinant Proteins; RNA, Messenger; Transcription, Genetic; Transfection; Triazoles; Tritium | 1999 |
Sensitization by chronic diazepam treatment of A2A adenosine receptor-mediated relaxation in rat pulmonary artery.
Topics: Adenosine; Animals; Carrier Proteins; Diazepam; Dinucleoside Phosphates; Dipyridamole; Dose-Response Relationship, Drug; Female; Heart; Heart Atria; Muscle Relaxation; Phenethylamines; Pulmonary Artery; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Rats; Rats, Wistar; Receptor, Adenosine A2A; Receptors, Purinergic P1; Thioinosine; Triazines; Triazoles; Verapamil | 1999 |
G protein coupling of CGS 21680 binding sites in the rat hippocampus and cortex is different from that of adenosine A1 and striatal A2A receptors.
Topics: Adenosine; Animals; Binding Sites; Binding, Competitive; Brain; Cerebral Cortex; Cholera Toxin; Corpus Striatum; Ethylmaleimide; GTP-Binding Proteins; Guanylyl Imidodiphosphate; Hippocampus; Male; Membranes; Pertussis Toxin; Phenethylamines; Purinergic P1 Receptor Agonists; Pyrimidines; Rats; Rats, Wistar; Receptors, Purinergic P1; Triazines; Triazoles; Tritium; Virulence Factors, Bordetella | 1999 |
Increase in the number, G protein coupling, and efficiency of facilitatory adenosine A2A receptors in the limbic cortex, but not striatum, of aged rats.
Topics: Adenosine; Aging; Animals; Cell Membrane; Cerebral Cortex; Corpus Striatum; Cyclic AMP; Dentate Gyrus; GTP-Binding Proteins; Kinetics; Limbic System; Male; Organ Specificity; Phenethylamines; Purinergic P1 Receptor Agonists; Radioligand Assay; Rats; Rats, Wistar; Receptor, Adenosine A2A; Receptors, Purinergic P1; Triazines; Triazoles; Tritium | 1999 |
Autoradiographic comparison of the potency of several structurally unrelated adenosine receptor antagonists at adenosine A1 and A(2A) receptors.
Topics: Adenosine; Animals; Autoradiography; Binding, Competitive; Brain; Caffeine; In Vitro Techniques; Male; Phenethylamines; Purinergic P1 Receptor Antagonists; Pyrazines; Quinazolines; Rats; Rats, Sprague-Dawley; Receptor, Adenosine A2A; Receptors, Purinergic P1; Theophylline; Triazines; Triazoles; Tritium; Xanthines | 1999 |
Effect of A2A adenosine receptor stimulation and antagonism on synaptic depression induced by in vitro ischaemia in rat hippocampal slices.
Topics: Adenosine; Animals; Excitatory Postsynaptic Potentials; Hippocampus; Hypoxia-Ischemia, Brain; In Vitro Techniques; Male; Phenethylamines; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Pyrimidines; Rats; Rats, Wistar; Receptor, Adenosine A2A; Synapses; Synaptic Transmission; Triazines; Triazoles; Xanthines | 1999 |
Increase in the vasorelaxant potency of K(ATP) channel opening drugs by adenosine A(1) and A(2) receptors in the pig coronary artery.
Topics: Adenosine; Animals; ATP-Binding Cassette Transporters; Coronary Vessels; Cromakalim; Dose-Response Relationship, Drug; Drug Interactions; In Vitro Techniques; KATP Channels; Nicorandil; Phenethylamines; Pinacidil; Potassium Channels; Potassium Channels, Inwardly Rectifying; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Swine; Triazines; Triazoles; Vasodilator Agents; Xanthines | 1999 |
Cross talk between A(1) and A(2A) adenosine receptors in the hippocampus and cortex of young adult and old rats.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Adenosine; Aging; Animals; Binding, Competitive; Cerebral Cortex; Electrophysiology; Hippocampus; In Vitro Techniques; Male; Phenethylamines; Protein Kinase C; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Rats; Rats, Wistar; Receptor Cross-Talk; Receptor, Adenosine A2A; Receptors, Purinergic P1; Synaptic Membranes; Triazines; Triazoles; Xanthines | 1999 |
Adenosine receptor occupancy suppresses chemoattractant-induced phospholipase D activity by diminishing membrane recruitment of small GTPases.
Topics: Adenosine; Adenosine Deaminase; Adenosine-5'-(N-ethylcarboxamide); ADP-Ribosylation Factor 1; Adult; Caffeine; Cell Membrane; Enzyme Activation; GTP Phosphohydrolases; Humans; In Vitro Techniques; Isoenzymes; Kinetics; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Phenethylamines; Phospholipase D; Protein Kinase C; Protein Kinase C-alpha; Purinergic P1 Receptor Antagonists; Quinazolines; Receptor, Adenosine A2A; Receptors, Purinergic P1; rhoA GTP-Binding Protein; Triazoles | 2000 |
The anxiogenic-like effect of caffeine in two experimental procedures measuring anxiety in the mouse is not shared by selective A(2A) adenosine receptor antagonists.
Topics: Adenosine; Administration, Oral; Animals; Anxiety; Behavior, Animal; Caffeine; Darkness; Drug Administration Schedule; Injections, Intraperitoneal; Light; Male; Maze Learning; Mice; Mice, Knockout; Neuroprotective Agents; Phenethylamines; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Pyrimidines; Reaction Time; Receptor, Adenosine A2A; Triazines; Triazoles; Xanthines | 2000 |
Antagonism of coronary artery relaxation by adenosine A2A-receptor antagonist ZM241385.
Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Antihypertensive Agents; Coronary Vessels; Dinoprost; Dose-Response Relationship, Drug; Drug Interactions; Endothelium, Vascular; In Vitro Techniques; Male; Muscle Relaxation; Muscle, Smooth, Vascular; Phenethylamines; Purinergic P1 Receptor Antagonists; Pyrimidines; Receptors, Purinergic P1; Swine; Triazines; Triazoles; Vasodilator Agents | 2000 |
Adenosine mediates nitric-oxide-independent renal vasodilation by activation of A2A receptors.
Topics: Adenosine; Animals; Endothelium, Vascular; Female; In Vitro Techniques; Male; Nitric Oxide; Phenethylamines; Potassium; Potassium Channels; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Rabbits; Receptors, Purinergic; Renal Artery; Triazines; Triazoles; Vasodilation; Vasodilator Agents | 1999 |
A galpha(s) carboxyl-terminal peptide prevents G(s) activation by the A(2A) adenosine receptor.
Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Binding, Competitive; Cell Membrane; GTP-Binding Protein alpha Subunits, Gs; In Vitro Techniques; Magnetic Resonance Spectroscopy; Male; Molecular Sequence Data; Peptides; Phenethylamines; Protein Conformation; Pyrimidines; Radioligand Assay; Rats; Rats, Sprague-Dawley; Receptor, Adenosine A2A; Receptors, Purinergic P1; Signal Transduction; Triazoles; Tritium | 2000 |
Accelerated resequestration of cytosolic calcium and suppression of the pro-inflammatory activities of human neutrophils by CGS 21680 in vitro.
Topics: Adenosine; Calcium; Calcium Radioisotopes; Cyclic AMP; Cytosol; Dose-Response Relationship, Drug; Fura-2; Humans; Inflammation; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Pancreatic Elastase; Phenethylamines; Purinergic P1 Receptor Agonists; Purinergic P2 Receptor Antagonists; Superoxides; Thapsigargin; Triazines; Triazoles | 2000 |
Down-regulation of vascular endothelial growth factor expression after A(2A) adenosine receptor activation in PC12 pheochromocytoma cells.
Topics: Adenosine; Animals; Down-Regulation; Endothelial Growth Factors; Gene Expression Regulation; Lymphokines; PC12 Cells; Phenethylamines; Rats; Receptors, Purinergic P1; RNA, Messenger; Signal Transduction; Triazines; Triazoles; Vascular Endothelial Growth Factor A; Vascular Endothelial Growth Factors | 2000 |
SCH 58261 and ZM 241385 differentially prevent the motor effects of CGS 21680 in mice: evidence for a functional 'atypical' adenosine A(2A) receptor.
Topics: Adenosine; Animals; Dose-Response Relationship, Drug; Drug Interactions; Exploratory Behavior; Injections, Intraventricular; Male; Maze Learning; Mice; Mice, Knockout; Motor Activity; Neuroprotective Agents; Phenethylamines; Pyrimidines; Receptor, Adenosine A2A; Receptors, Purinergic P1; Time Factors; Triazines; Triazoles | 2000 |
Adenosine A(2A) and A(2B) receptors in cultured human and porcine coronary artery endothelial cells.
Topics: 2-Chloroadenosine; Adenosine; Adenosine-5'-(N-ethylcarboxamide); Affinity Labels; Animals; Binding, Competitive; Cells, Cultured; Coronary Vessels; Cyclic AMP; Endothelium, Vascular; Gene Expression Regulation; Humans; Iodine Radioisotopes; Iodobenzenes; Kinetics; Phenethylamines; Purinergic P1 Receptor Antagonists; Radioligand Assay; Receptor, Adenosine A2A; Receptor, Adenosine A2B; Receptors, Purinergic P1; Reverse Transcriptase Polymerase Chain Reaction; Swine; Transcription, Genetic; Triazines; Triazoles | 2000 |
Adenosine and selective A(2A) receptor agonists reduce ischemia/reperfusion injury of rat liver mainly by inhibiting leukocyte activation.
Topics: Adenosine; Alkynes; Animals; Calcium; Cells, Cultured; Chemokine CXCL1; Chemokines, CXC; Chemotactic Factors; Growth Substances; Humans; Intercellular Signaling Peptides and Proteins; Ischemia; Leukocyte Elastase; Lipopolysaccharides; Liver; Male; Monocytes; Neutrophil Activation; Peroxidase; Phenethylamines; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Rats; Rats, Wistar; Receptor, Adenosine A2A; Reperfusion Injury; Triazines; Triazoles; Tumor Necrosis Factor-alpha | 2000 |
Adenosine A(2A) receptors mediate cardiovascular responses to hypoxia in fetal sheep.
Topics: Adenosine; Animals; Blood Gas Analysis; Blood Pressure; Female; Fetal Hypoxia; Heart Rate; Hydrogen-Ion Concentration; Phenethylamines; Pregnancy; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Receptor, Adenosine A2A; Receptors, Purinergic P1; Sheep; Triazines; Triazoles; Xanthines | 2001 |
Functional and molecular characterization of receptor subtypes mediating coronary microvascular dilation to adenosine.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Adenosine; Animals; Antihypertensive Agents; Blotting, Western; Colforsin; Coronary Vessels; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Dose-Response Relationship, Drug; Enzyme Inhibitors; Enzyme-Linked Immunosorbent Assay; Female; Glyburide; Heart; Hypoglycemic Agents; In Situ Hybridization; Male; Microcirculation; Myocardium; Peptides; Phenethylamines; Potassium Channel Blockers; Purinergic P1 Receptor Antagonists; Receptors, Purinergic P1; Reverse Transcriptase Polymerase Chain Reaction; Stress, Physiological; Swine; Thionucleotides; Tissue Distribution; Triazines; Triazoles | 2001 |
Receptor subtypes mediating adenosine-induced dilation of cerebral arterioles.
Topics: Adenosine; Adenosine Triphosphate; Animals; Antihypertensive Agents; Arterioles; Cerebrovascular Circulation; Dose-Response Relationship, Drug; In Vitro Techniques; Male; Phenethylamines; Quinazolines; Rats; Rats, Sprague-Dawley; Receptors, Purinergic P1; Triazines; Triazoles; Vasodilation | 2001 |
Novel short-acting A2A adenosine receptor agonists for coronary vasodilation: inverse relationship between affinity and duration of action of A2A agonists.
Topics: Adenosine; Animals; Antihypertensive Agents; Coronary Vessels; Corpus Striatum; Cyclic AMP; Dose-Response Relationship, Drug; Female; Humans; Male; PC12 Cells; Phenethylamines; Purinergic P1 Receptor Agonists; Purines; Pyrazoles; Rats; Receptor, Adenosine A2A; Receptors, Purinergic P1; Swine; Triazines; Triazoles; Vasodilation; Vasodilator Agents | 2001 |
Suppression of presynaptic responses to adenosine by activation of NMDA receptors.
Topics: Action Potentials; Adenosine; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Baclofen; Dose-Response Relationship, Drug; Excitatory Amino Acid Agonists; GABA Agonists; Glycine; Hippocampus; In Vitro Techniques; Kainic Acid; Long-Term Potentiation; Male; N-Methylaspartate; Phenethylamines; Presynaptic Terminals; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Rats; Rats, Wistar; Receptor, Adenosine A2A; Receptors, N-Methyl-D-Aspartate; Time Factors; Triazines; Triazoles | 2001 |
Effects of adenosine receptor agonists and antagonists in a genetic animal model of primary paroxysmal dystonia.
Topics: Adenosine; Animals; Caffeine; Cricetinae; Disease Models, Animal; Dose-Response Relationship, Drug; Dystonia; Female; Male; Mesocricetus; Muscle Contraction; Mutation; Phenethylamines; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Quinazolines; Theobromine; Theophylline; Triazines; Triazoles; Xanthines | 2001 |
Adenosine A(2A) and A(2B) receptor activation of erythropoietin production.
Topics: Adenosine; Alkaloids; Benzophenanthridines; Carcinoma, Hepatocellular; Enzyme Activation; Erythropoietin; Humans; Liver Neoplasms; Phenanthridines; Phenethylamines; Protein Kinase C; Purinergic P1 Receptor Antagonists; Pyrimidines; Receptor, Adenosine A2A; Receptor, Adenosine A2B; Receptors, Purinergic P1; RNA, Messenger; Triazoles; Tumor Cells, Cultured; Xanthines | 2001 |
Adenosine-mediated hypotension in in vivo guinea-pig: receptors involved and role of NO.
Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Blood Pressure; Diphenhydramine; Dose-Response Relationship, Drug; Enzyme Inhibitors; Guinea Pigs; Heart Rate; Hypotension; Male; Methylene Blue; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Phenethylamines; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Receptors, Purinergic P1; Theophylline; Triazines; Triazoles; Vasodilator Agents; Xanthines | 2001 |
Solubilisation and immunoprecipitation of rat striatal adenosine A(2A) receptors.
Topics: Adenosine; Animals; Cholic Acids; Corpus Striatum; Detergents; Phenethylamines; Precipitin Tests; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Purines; Radioligand Assay; Rats; Receptor, Adenosine A2A; Receptors, Purinergic P1; Solubility; Triazines; Triazoles | 2001 |
Adenosine inhibits excitatory transmission to substantia gelatinosa neurons of the adult rat spinal cord through the activation of presynaptic A(1) adenosine receptor.
Topics: Adenosine; Age Factors; Analgesics; Animals; Antihypertensive Agents; Excitatory Postsynaptic Potentials; In Vitro Techniques; Male; Neural Inhibition; Neurons; Patch-Clamp Techniques; Phenethylamines; Rats; Rats, Sprague-Dawley; Receptors, Purinergic P1; Substantia Gelatinosa; Triazines; Triazoles; Xanthines | 2001 |
Effects of A(3) adenosine receptor activation and gene knock-out in ischemic-reperfused mouse heart.
Topics: Adenosine; Amino Acids; Animals; Creatine; Heart Rate; Hydrogen-Ion Concentration; Magnetic Resonance Spectroscopy; Mice; Mice, Inbred C57BL; Mice, Knockout; Myocardial Contraction; Myocardial Reperfusion Injury; Myocardium; Perfusion; Phenethylamines; Pipecolic Acids; Purinergic P1 Receptor Antagonists; Quinazolines; Receptor, Adenosine A3; Receptors, Purinergic P1; Triazoles; Xanthines | 2002 |
Effects of CGS 21680, a selective adenosine A2A receptor agonist, on allergic airways inflammation in the rat.
Topics: Adenosine; Allergens; Animals; Anti-Inflammatory Agents; Asthma; Blood Pressure; Budesonide; Dose-Response Relationship, Drug; Inflammation; Lung; Male; Ovalbumin; Phenethylamines; Purinergic P1 Receptor Agonists; Rats; Rats, Inbred BN; Receptor, Adenosine A2A; Triazines; Triazoles; Vascular Resistance | 2002 |
Targeted deletion of adenosine A(3) receptors augments adenosine-induced coronary flow in isolated mouse heart.
Topics: Adenosine; Animals; Coronary Circulation; Coronary Vessels; Gene Deletion; Heart Rate; Mice; Mice, Knockout; Phenethylamines; Quinazolines; Receptor, Adenosine A3; Receptors, Purinergic P1; Triazoles; Vasodilation; Ventricular Pressure | 2002 |
Effects of adenosine A1 and A2A receptor activation on the evoked release of glutamate from rat cerebrocortical synaptosomes.
Topics: Adenosine; Analysis of Variance; Animals; Cerebral Cortex; Chromatography, High Pressure Liquid; Glutamic Acid; In Vitro Techniques; Male; Phenethylamines; Purinergic P1 Receptor Agonists; Pyrimidines; Rats; Rats, Sprague-Dawley; Receptor, Adenosine A2A; Synaptosomes; Triazoles; Xanthines | 2002 |
Adenosine A(2A) receptor facilitation of hippocampal synaptic transmission is dependent on tonic A(1) receptor inhibition.
Topics: Adenosine; Animals; Binding, Competitive; CHO Cells; Cricetinae; Cyclic AMP; Enzyme Inhibitors; Excitatory Postsynaptic Potentials; GABA Antagonists; gamma-Aminobutyric Acid; Glutamic Acid; Hippocampus; Humans; In Vitro Techniques; Ligands; Male; Phenethylamines; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Rats; Rats, Wistar; Receptor, Adenosine A2A; Receptors, Purinergic P1; Signal Transduction; Synaptic Transmission; Transfection; Triazines; Triazoles; Xanthines | 2002 |
Synergistic up-regulation of vascular endothelial growth factor expression in murine macrophages by adenosine A(2A) receptor agonists and endotoxin.
Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Blotting, Western; Cells, Cultured; Drosophila Proteins; Endothelial Growth Factors; Female; Interferon-gamma; Lipopolysaccharides; Lymphokines; Macrophages, Peritoneal; Male; Membrane Glycoproteins; Mice; Mice, Inbred C3H; Mice, Inbred C57BL; Mice, Knockout; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Phenethylamines; Protein Kinase Inhibitors; Purinergic P1 Receptor Agonists; Receptor, Adenosine A2A; Receptors, Cell Surface; Receptors, Purinergic P1; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Signal Transduction; Theobromine; Toll-Like Receptor 4; Toll-Like Receptors; Triazines; Triazoles; Up-Regulation; Vascular Endothelial Growth Factor A; Vascular Endothelial Growth Factors; Xanthines | 2002 |
Selective allosteric enhancement of agonist binding and function at human A3 adenosine receptors by a series of imidazoquinoline derivatives.
Topics: Adenosine; Allosteric Regulation; Animals; Binding, Competitive; CHO Cells; Cricetinae; Dose-Response Relationship, Drug; Imidazoles; Iodine Radioisotopes; Phenethylamines; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Purines; Quinolines; Radioligand Assay; Rats; Receptor, Adenosine A2A; Receptor, Adenosine A3; Receptors, Purinergic P1; Triazines; Triazoles; Tritium; Xanthines | 2002 |
Effects of adenosine receptor agonists on guinea-pig isolated working hearts and the role of endothelium and NO.
Topics: Adenosine; Animals; Cyclooxygenase Inhibitors; Endothelium, Vascular; Guinea Pigs; Heart; Hemodynamics; In Vitro Techniques; Indomethacin; Male; Nitric Oxide; Nitric Oxide Synthase; Phenethylamines; Prostaglandins; Purinergic P1 Receptor Agonists; Triazines; Triazoles | 2002 |
Involvement of DARPP-32 phosphorylation in the stimulant action of caffeine.
Topics: Adenosine; Animals; Caffeine; Central Nervous System Stimulants; Cyclin-Dependent Kinase 5; Cyclin-Dependent Kinases; Dopamine and cAMP-Regulated Phosphoprotein 32; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Motor Activity; Neostriatum; Nerve Tissue Proteins; Neurons; Phenethylamines; Phosphoproteins; Phosphorylation; Phosphothreonine; Purinergic P1 Receptor Antagonists; Pyrimidines; Receptors, Purinergic P1; Triazoles | 2002 |
Positive coupling of atypical adenosine A3 receptors on human eosinophils to adenylyl cyclase.
Topics: Adenosine; Adenylyl Cyclases; Adult; Cell Degranulation; Cyclic AMP; Cyclooxygenase Inhibitors; Dose-Response Relationship, Drug; Eosinophils; Histamine; Humans; Phenethylamines; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Quinazolines; Receptor, Adenosine A2A; Receptor, Adenosine A3; Receptors, Purinergic P1; Triazoles | 2003 |
Regional differences in the adenosine A(2) receptor-mediated modulation of contractions in rat vas deferens.
Topics: Adenosine; Adenosine Triphosphate; Adenosine-5'-(N-ethylcarboxamide); Animals; Epididymis; Immunohistochemistry; In Vitro Techniques; Male; Muscle Contraction; Norepinephrine; Phenethylamines; Prostate; Rats; Rats, Wistar; Receptor, Adenosine A2A; Receptors, Purinergic P1; Theobromine; Triazines; Triazoles; Vas Deferens; Xanthines | 2003 |
Involvement of adenosine A1 and A2A receptors in the motor effects of caffeine after its acute and chronic administration.
Topics: Adenosine; Amphetamine; Animals; Behavior, Animal; Caffeine; Central Nervous System Stimulants; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Interactions; Male; Motor Activity; Phenethylamines; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Radioligand Assay; Rats; Rats, Sprague-Dawley; Receptor, Adenosine A2A; Receptors, Purinergic P1; Theophylline; Time Factors; Triazines; Triazoles; Tritium; Xanthines | 2003 |
Binding of HTLV-1 virions to T cells occurs by a temperature and calcium-dependent process and is blocked by certain type 2 adenosine receptor antagonists.
Topics: 2-Chloroadenosine; Adenosine; Adenosine-5'-(N-ethylcarboxamide); Antibodies, Monoclonal; Calcium; Cations, Divalent; Cell Line, Transformed; Human T-lymphotropic virus 1; Humans; Kinetics; Membrane Microdomains; Phenethylamines; Purinergic P1 Receptor Agonists; Quinazolines; T-Lymphocytes; Thermodynamics; Triazoles | 2003 |
The human D2 dopamine receptor synergizes with the A2A adenosine receptor to stimulate adenylyl cyclase in PC12 cells.
Topics: 4-(3-Butoxy-4-methoxybenzyl)-2-imidazolidinone; Adenine; Adenosine; Adenosine Deaminase; Adenosine Diphosphate; Adenylyl Cyclases; Animals; Benzamides; Binding, Competitive; Cell Cycle; Cell Membrane; Cofilin 1; Colforsin; Cyclic AMP; Cytoskeletal Proteins; Dopamine Agonists; Dopamine Antagonists; Dopamine D2 Receptor Antagonists; Enzyme Activation; Gene Expression; Glutamic Acid; Humans; Membrane Potentials; Patch-Clamp Techniques; PC12 Cells; Pertussis Toxin; Phenethylamines; Phosphodiesterase Inhibitors; Phosphoproteins; Propionates; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Pyrrolidines; Quinpirole; Radioligand Assay; Rats; Receptors, Dopamine D2; Receptors, Purinergic P1; Thionucleotides; Transfection; Triazines; Triazoles; Xenopus Proteins | 2003 |
Blockade of A2A adenosine receptors prevents basic fibroblast growth factor-induced reactive astrogliosis in rat striatal primary astrocytes.
Topics: Adenosine; Adenosine A2 Receptor Agonists; Adenosine A2 Receptor Antagonists; Adenosine-5'-(N-ethylcarboxamide); Animals; Animals, Newborn; Astrocytes; Cell Division; Cells, Cultured; Cerebral Cortex; Corpus Striatum; Dose-Response Relationship, Drug; Drug Interactions; Fibroblast Growth Factor 2; Fluorescent Antibody Technique; Glial Fibrillary Acidic Protein; Gliosis; Neuroprotective Agents; Phenethylamines; Purines; Pyrimidines; Rats; Receptor, Adenosine A2A; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Triazoles; Vasodilator Agents | 2003 |
Adenosine A 2B receptors modulate cAMP levels and induce CREB but not ERK1/2 and p38 phosphorylation in rat skeletal muscle cells.
Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Cells, Cultured; Cyclic AMP; Cyclic AMP Response Element-Binding Protein; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; Muscle, Skeletal; p38 Mitogen-Activated Protein Kinases; Pertussis Toxin; Phenethylamines; Phosphorylation; Rats; Receptor, Adenosine A2A; Receptor, Adenosine A2B; Receptors, Purinergic P1; RNA; Triazines; Triazoles | 2003 |
Enhanced adenosine A2A receptor facilitation of synaptic transmission in the hippocampus of aged rats.
Topics: Adenosine; Adrenergic beta-Agonists; Aging; Animals; Blotting, Western; Cyclic AMP; Electrophysiology; Excitatory Postsynaptic Potentials; Hippocampus; Isoproterenol; Male; Neurons; Phenethylamines; Presynaptic Terminals; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Rats; Rats, Wistar; Receptor, Adenosine A2A; Receptors, Purinergic P1; Synaptic Transmission; Triazines; Triazoles; Xanthines | 2003 |
Discovery of nonxanthine adenosine A2A receptor antagonists for the treatment of Parkinson's disease.
Topics: Adenosine; Adenosine A2 Receptor Antagonists; Animals; Antiparkinson Agents; Binding, Competitive; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Design; Drug Evaluation, Preclinical; Humans; Ligands; Mefloquine; Mice; Motor Activity; Neuroprotective Agents; Parkinsonian Disorders; Phenethylamines; Purines; Pyrimidines; Radioligand Assay; Rats; Triazines; Triazoles | 2003 |
Input-specific modulation of neurotransmitter release in the lateral horn of the spinal cord via adenosine receptors.
Topics: Adenosine; Adenosine A2 Receptor Agonists; Adenosine A2 Receptor Antagonists; Animals; Cells, Cultured; Excitatory Postsynaptic Potentials; Immunohistochemistry; Interneurons; Male; Neural Inhibition; Neurons; Neurotransmitter Agents; Patch-Clamp Techniques; Phenethylamines; Presynaptic Terminals; Rats; Receptor, Adenosine A1; Receptor, Adenosine A2A; Spinal Cord; Triazines; Triazoles | 2004 |
Role of adenosine A2A receptor in the regulation of gastric somatostatin release.
Topics: Adenosine; Adenosine A2 Receptor Agonists; Adenosine A2 Receptor Antagonists; Animals; Gastric Mucosa; Male; Phenethylamines; Rats; Rats, Wistar; Receptor, Adenosine A2A; Somatostatin; Stomach; Tissue Distribution; Triazines; Triazoles; Xanthines | 2004 |
Synthesis and structure-activity relationships of 4-cycloalkylamino-1, 2, 4-triazolo[4, 3-a]quinoxalin-1- one derivatives as A1 and A3 adenosine receptor antagonists.
Topics: Adenosine; Alkanes; Animals; Binding Sites; Binding, Competitive; Cattle; Cerebral Cortex; CHO Cells; Cricetinae; Humans; Iodine Isotopes; Membranes; Neostriatum; Phenethylamines; Purinergic Antagonists; Quantitative Structure-Activity Relationship; Quinoxalines; Receptors, Purinergic; Triazoles; Tritium | 2004 |
Binding of the prototypical adenosine A(2A) receptor agonist CGS 21680 to the cerebral cortex of adenosine A(1) and A(2A) receptor knockout mice.
Topics: Adenosine; Adenosine A1 Receptor Antagonists; Adenosine A2 Receptor Agonists; Animals; Autoradiography; Basal Ganglia; Binding, Competitive; Blotting, Western; Cerebral Cortex; Electrophoresis, Polyacrylamide Gel; Mice; Mice, Knockout; Models, Animal; Phenethylamines; Pyrimidines; Receptor, Adenosine A1; Receptor, Adenosine A2A; Triazoles; Tritium; Xanthines | 2004 |
Activation of adenosine A2A receptor facilitates brain-derived neurotrophic factor modulation of synaptic transmission in hippocampal slices.
Topics: Adenosine; Adenosine Kinase; Animals; Brain-Derived Neurotrophic Factor; Bucladesine; Carbazoles; Electric Stimulation; Enzyme Inhibitors; Excitatory Postsynaptic Potentials; Hippocampus; In Vitro Techniques; Indole Alkaloids; Long-Term Potentiation; Male; Patch-Clamp Techniques; Phenethylamines; Potassium; Rats; Rats, Wistar; Receptor, Adenosine A2A; Receptor, trkB; Synaptic Transmission; Triazines; Triazoles | 2004 |
Adenosine A2A receptor occupancy stimulates expression of proteins involved in reverse cholesterol transport and inhibits foam cell formation in macrophages.
Topics: Adenosine; Adenosine A2 Receptor Agonists; Adenosine A2 Receptor Antagonists; Animals; Arteriosclerosis; ATP Binding Cassette Transporter 1; ATP-Binding Cassette Transporters; Carrier Proteins; Cell Differentiation; Cholestanetriol 26-Monooxygenase; Cholesterol; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Down-Regulation; Foam Cells; Gene Expression Regulation, Enzymologic; Humans; Macrophages; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Phenethylamines; Receptor, Adenosine A2A; RNA, Messenger; Steroid Hydroxylases; Triazines; Triazoles; Up-Regulation | 2004 |
Adenosine A2A receptor blockade differentially influences excitotoxic mechanisms at pre- and postsynaptic sites in the rat striatum.
Topics: 4-Aminopyridine; Adenosine; Adenosine A2 Receptor Antagonists; Animals; Calcium; Corpus Striatum; Dose-Response Relationship, Drug; Glutamic Acid; In Vitro Techniques; L-Lactate Dehydrogenase; Male; Models, Biological; N-Methylaspartate; Neurodegenerative Diseases; Neurons; Neuroprotective Agents; Neurotoxins; Phenethylamines; Pyrimidines; Quinolinic Acid; Rats; Rats, Wistar; Receptor, Adenosine A2A; Receptors, N-Methyl-D-Aspartate; Synaptic Membranes; Synaptic Transmission; Triazines; Triazoles | 2004 |
Facilitation of noradrenaline release by activation of adenosine A(2A) receptors triggers both phospholipase C and adenylate cyclase pathways in rat tail artery.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Adenosine; Adenylyl Cyclases; Animals; Arteries; Cyclic AMP-Dependent Protein Kinases; Endothelium, Vascular; Enzyme Activation; Indoles; Isoquinolines; Male; Norepinephrine; Phenethylamines; Pyrimidines; Pyrroles; Rats; Rats, Wistar; Receptor, Adenosine A2A; Signal Transduction; Sulfonamides; Tail; Tetradecanoylphorbol Acetate; Triazoles; Tritium; Type C Phospholipases | 2004 |
Permissive role of adenosine A2A receptors on metabotropic glutamate receptor 5 (mGluR5)-mediated effects in the striatum.
Topics: Adenosine; Animals; Carbazoles; Cells, Cultured; Corpus Striatum; Dose-Response Relationship, Drug; Drug Interactions; Electrophysiology; Embryo, Mammalian; Enzyme Inhibitors; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Female; Glycine; In Vitro Techniques; Indoles; Male; Membrane Potentials; N-Methylaspartate; Phenethylamines; Phenylacetates; Pregnancy; Purinergic P1 Receptor Agonists; Pyridines; Pyrroles; Rats; Rats, Wistar; Receptor, Metabotropic Glutamate 5; Receptors, Adenosine A2; Receptors, Metabotropic Glutamate; Triazines; Triazoles | 2004 |
Regulation of A2B adenosine receptor functioning by tumour necrosis factor a in human astroglial cells.
Topics: Adenosine; Adenosine A2 Receptor Antagonists; Adenosine-5'-(N-ethylcarboxamide); Animals; Antineoplastic Agents; Astrocytes; Astrocytoma; Blotting, Western; Cell Growth Processes; Cell Line, Tumor; Cricetinae; Cricetulus; Cyclic AMP; Dose-Response Relationship, Drug; Enzyme Inhibitors; Gene Expression Regulation; Guanosine 5'-O-(3-Thiotriphosphate); Humans; Immunoprecipitation; Neuroprotective Agents; Phenethylamines; Purines; Pyrimidines; Radioligand Assay; Receptor, Adenosine A2B; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Threonine; Time Factors; Transfection; Triazoles; Tumor Necrosis Factor-alpha | 2004 |
Co-localization and functional interaction between adenosine A(2A) and metabotropic group 5 receptors in glutamatergic nerve terminals of the rat striatum.
Topics: Adenosine; Adenosine A2 Receptor Agonists; Adenosine A2 Receptor Antagonists; Animals; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Glutamic Acid; Male; Neostriatum; Phenethylamines; Presynaptic Terminals; Pyrimidines; Rats; Rats, Wistar; Receptor, Adenosine A2A; Receptor, Metabotropic Glutamate 5; Receptors, Metabotropic Glutamate; Subcellular Fractions; Synaptosomes; Triazoles; Xanthines | 2005 |
Kinetic and functional properties of [3H]ZM241385, a high affinity antagonist for adenosine A2A receptors.
Topics: Adenosine; Adenosine A2 Receptor Antagonists; Algorithms; Animals; Binding, Competitive; Cell Membrane; CHO Cells; Cricetinae; Cyclic AMP; GTP-Binding Proteins; Kinetics; Ligands; Neostriatum; Phenethylamines; Radioligand Assay; Triazines; Triazoles | 2005 |
Upregulation of A2A adenosine receptor expression by TNF-alpha in PBMC of patients with CHF: a regulatory mechanism of inflammation.
Topics: Adenosine; Blotting, Western; Female; Heart Failure; Humans; Lipopolysaccharides; Male; Middle Aged; Neutrophils; Phenethylamines; Receptor, Adenosine A2A; Receptors, Purinergic P1; Reverse Transcriptase Polymerase Chain Reaction; Triazines; Triazoles; Tumor Necrosis Factor-alpha; Up-Regulation | 2005 |
Activation of adenosine receptors in the posterior cingulate cortex impairs memory retrieval in the rat.
Topics: Adenosine; Animals; Avoidance Learning; Cerebral Cortex; Exploratory Behavior; Gyrus Cinguli; Male; Memory; Microinjections; Phenethylamines; Purinergic Agonists; Purinergic Antagonists; Rats; Rats, Wistar; Receptor, Adenosine A1; Receptor, Adenosine A2A; Triazines; Triazoles; Xanthines | 2005 |
Effects of adenosine and adenosine A2A receptor agonist on motor nerve conduction velocity and nerve blood flow in experimental diabetic neuropathy.
Topics: Adenosine; Animals; Blood Glucose; Body Weight; Diabetes Mellitus, Experimental; Dose-Response Relationship, Drug; Drug Interactions; Neural Conduction; Phenethylamines; Purinergic P2 Receptor Agonists; Rats; Regional Blood Flow; Sciatic Nerve; Staining and Labeling; Streptozocin; Theophylline; Time Factors; Triazines; Triazoles | 2005 |
Adenosine A2A receptor stimulation potentiates nitric oxide release by activated microglia.
Topics: Adenosine; Adenosine A2 Receptor Antagonists; Analysis of Variance; Animals; Animals, Newborn; Blotting, Western; Cell Proliferation; Cells, Cultured; Cerebral Cortex; Dose-Response Relationship, Drug; Drug Interactions; Enzyme Inhibitors; Immunohistochemistry; Indoles; Lipopolysaccharides; Maleimides; Mice; Mice, Inbred C57BL; Microglia; Nitric Oxide; Nitrites; Phenethylamines; Protein Binding; Radioligand Assay; Receptor, Adenosine A2A; Time Factors; Triazines; Triazoles; Tritium; Tumor Necrosis Factor-alpha | 2005 |
Adenosine A1 and A2A receptors of hippocampal CA1 region have opposite effects on piriform cortex kindled seizures in rats.
Topics: Adenosine; Adenosine A1 Receptor Agonists; Adenosine A1 Receptor Antagonists; Adenosine A2 Receptor Agonists; Adenosine A2 Receptor Antagonists; Animals; Cerebral Cortex; Electric Stimulation; Hippocampus; Kindling, Neurologic; Male; Phenethylamines; Rats; Rats, Sprague-Dawley; Receptor, Adenosine A1; Receptor, Adenosine A2A; Receptors, Purinergic P2; Seizures; Triazines; Triazoles; Xanthines | 2006 |
A2a receptors mediate inhibitory effects of adenosine on colonic motility in the presence of experimental colitis.
Topics: Adenosine; Animals; Colitis; Disease Models, Animal; Gastrointestinal Motility; Intestinal Mucosa; Male; Muscle Contraction; Muscle, Smooth; Nitric Oxide; Phenethylamines; Rats; Rats, Sprague-Dawley; Receptor, Adenosine A2A; Reverse Transcriptase Polymerase Chain Reaction; Sensitivity and Specificity; Tissue Culture Techniques; Triazines; Triazoles | 2006 |
Dialysis delivery of an adenosine A2A agonist into the pontine reticular formation of C57BL/6J mouse increases pontine acetylcholine release and sleep.
Topics: Acetylcholine; Adenosine; Adenosine A2 Receptor Agonists; Adenosine A2 Receptor Antagonists; Animals; Dose-Response Relationship, Drug; Extracellular Fluid; gamma-Aminobutyric Acid; Male; Mice; Mice, Inbred C57BL; Microdialysis; Neural Inhibition; Neural Pathways; Phenethylamines; Pons; Receptor, Adenosine A2A; Reticular Formation; Sleep; Sleep, REM; Synaptic Transmission; Triazines; Triazoles; Up-Regulation; Wakefulness | 2006 |
Adenosine A2A receptor stimulation decreases GAT-1-mediated GABA uptake in the globus pallidus of the rat.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Adenosine; Adenosine A2 Receptor Agonists; Animals; Colforsin; Cyclic AMP-Dependent Protein Kinases; Data Interpretation, Statistical; Enzyme Inhibitors; GABA Plasma Membrane Transport Proteins; gamma-Aminobutyric Acid; Globus Pallidus; In Vitro Techniques; Isoquinolines; Male; Okadaic Acid; Phenethylamines; Rats; Rats, Wistar; Sulfonamides; Synapses; Triazines; Triazoles | 2006 |
Role of adenosine A1 receptors in the modulation of dopamine D1 and adenosine A2A receptor signaling in the neostriatum.
Topics: Adenosine; Adenosine A1 Receptor Agonists; Adenosine A1 Receptor Antagonists; Adenosine A2 Receptor Antagonists; Animals; Benzazepines; Dopamine and cAMP-Regulated Phosphoprotein 32; Dopamine Antagonists; Drug Interactions; Gene Expression; In Vitro Techniques; Mice; Mice, Inbred C57BL; Neostriatum; Phenethylamines; Raclopride; Receptor, Adenosine A1; Receptor, Adenosine A2A; Receptors, Dopamine D1; Signal Transduction; Threonine; Triazines; Triazoles; Xanthines | 2006 |
Evidence for both adenosine A1 and A2A receptors activating single vagal sensory C-fibres in guinea pig lungs.
Topics: Action Potentials; Adenosine; Adenosine A1 Receptor Antagonists; Adenosine A2 Receptor Antagonists; Animals; Capsaicin; Gene Expression Regulation; Guinea Pigs; Lung; Male; Nerve Fibers, Unmyelinated; Neurons; Nodose Ganglion; Patch-Clamp Techniques; Phenethylamines; Pyrimidines; Receptor, Adenosine A1; Receptors, Adenosine A2; RNA, Messenger; Triazoles; Xanthines | 2006 |
Contribution of adenosine receptors in the control of arteriolar tone and adenosine-angiotensin II interaction.
Topics: Adenosine; Adenosine A1 Receptor Agonists; Adenosine A1 Receptor Antagonists; Adenosine A2 Receptor Agonists; Adenosine A2 Receptor Antagonists; Angiotensin II; Animals; Arterioles; Feedback; Female; Kidney Glomerulus; Kidney Tubules; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Phenethylamines; Purines; Receptor, Adenosine A1; Receptors, Adenosine A2; Theophylline; Triazines; Triazoles; Vasoconstriction; Vasodilation | 2006 |
Adenosine A2A receptor modulation of juvenile female rat skeletal muscle microvessel permeability.
Topics: Adenine; Adenosine; Adenosine A2 Receptor Agonists; Adenosine A2 Receptor Antagonists; Adenylyl Cyclase Inhibitors; Adenylyl Cyclases; Aging; Animals; Arterioles; Cell Membrane Permeability; Dose-Response Relationship, Drug; Enzyme Inhibitors; Female; Gene Expression Regulation; Muscle, Skeletal; Phenethylamines; Rats; Rats, Sprague-Dawley; Receptor, Adenosine A1; Receptor, Adenosine A2A; Receptor, Adenosine A2B; RNA, Messenger; Serum Albumin; Triazines; Triazoles; Vasodilator Agents; Venules | 2006 |
Glial cell line-derived neurotrophic factor (GDNF) enhances dopamine release from striatal nerve endings in an adenosine A2A receptor-dependent manner.
Topics: Adenosine; Adenosine A2 Receptor Agonists; Adenosine A2 Receptor Antagonists; Analysis of Variance; Animals; Bicuculline; Corpus Striatum; Dopamine; Dose-Response Relationship, Drug; Drug Interactions; GABA Antagonists; Glial Cell Line-Derived Neurotrophic Factor; In Vitro Techniques; Male; Nerve Endings; Phenethylamines; Potassium; Pyrimidines; Rats; Rats, Wistar; Receptor, Adenosine A2A; Synaptosomes; Triazoles; Tritium | 2006 |
Expression of adenosine receptors in cardiac fibroblasts as a function of insulin and glucose level.
Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Adenylyl Cyclases; Animals; Blotting, Western; Cells, Cultured; Cyclic AMP; Dose-Response Relationship, Drug; Fibroblasts; Gene Expression; Glucose; Heart Ventricles; Insulin; Male; Phenethylamines; Protein Isoforms; Rats; Rats, Wistar; Receptors, Purinergic P1; RNA, Messenger; Triazines; Triazoles | 2006 |
Stimulation of adenosine A1 and A2A receptors by AMP in the submucosal plexus of guinea pig small intestine.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Action Potentials; Adenosine; Adenosine A1 Receptor Antagonists; Adenosine A2 Receptor Antagonists; Adenosine Diphosphate; Adenosine Monophosphate; Animals; Boron Compounds; Enzyme Inhibitors; Estrenes; Excitatory Postsynaptic Potentials; Guinea Pigs; Ileum; Indoles; Male; Maleimides; Norepinephrine; Phenethylamines; Pyrrolidinones; Quinazolines; Receptor, Adenosine A1; Receptor, Adenosine A2A; Signal Transduction; Submucous Plexus; Synaptic Transmission; Tetrodotoxin; Theophylline; Triazines; Triazoles | 2007 |
Characterization of the potency, selectivity, and pharmacokinetic profile for six adenosine A2A receptor antagonists.
Topics: Adenosine; Adenosine A2 Receptor Antagonists; Adenosine A3 Receptor Antagonists; Animals; Binding, Competitive; Biological Availability; Cell Line; Cyclic AMP; Dose-Response Relationship, Drug; Humans; Male; Metabolic Clearance Rate; Molecular Structure; PC12 Cells; Phenethylamines; Purines; Pyrimidines; Rats; Rats, Sprague-Dawley; Receptor, Adenosine A2A; Receptor, Adenosine A3; Theobromine; Triazines; Triazoles; Xanthines | 2007 |
The role of adenosine A2a receptors in experimental acute pancreatitis.
Topics: Acute Disease; Adenosine; Adenosine A2 Receptor Agonists; Adenosine A2 Receptor Antagonists; Amylases; Animals; Disease Models, Animal; Immunohistochemistry; Lipase; Male; Pancreas; Pancreatitis; Phenethylamines; Rats; Rats, Wistar; Receptor, Adenosine A2A; Taurocholic Acid; Triazines; Triazoles | 2006 |
Adenosine closes the K+ channel KCa3.1 in human lung mast cells and inhibits their migration via the adenosine A2A receptor.
Topics: Adenosine; Adenosine A2 Receptor Agonists; Adenosine A2 Receptor Antagonists; Benzimidazoles; Calcium Channel Agonists; Cations; Cell Movement; Culture Media, Conditioned; Electric Stimulation; Electrophysiology; Histamine; Humans; Immunoglobulin E; Intermediate-Conductance Calcium-Activated Potassium Channels; Lung; Mast Cells; Phenethylamines; Receptor, Adenosine A2A; Receptor, Adenosine A2B; Triazines; Triazoles | 2007 |
The role of adenosine A1 and A2A receptors of entorhinal cortex on piriform cortex kindled seizures in rats.
Topics: Adenosine; Animals; Anticonvulsants; Convulsants; Disease Models, Animal; Electric Stimulation; Electrodes, Implanted; Entorhinal Cortex; Kindling, Neurologic; Male; Microinjections; Phenethylamines; Rats; Rats, Sprague-Dawley; Receptor, Adenosine A1; Receptor, Adenosine A2A; Seizures; Triazines; Triazoles; Xanthines | 2007 |
Anticonvulsant effect of A1 but not A2A adenosine receptors of piriform cortex in amygdala-kindled rats.
Topics: Adenosine; Adenosine A1 Receptor Agonists; Adenosine A1 Receptor Antagonists; Adenosine A2 Receptor Agonists; Adenosine A2 Receptor Antagonists; Amygdala; Analysis of Variance; Animals; Anticonvulsants; Dose-Response Relationship, Drug; Electric Stimulation; Evoked Potentials; Kindling, Neurologic; Male; Microinjections; Models, Anatomic; Phenethylamines; Rats; Rats, Sprague-Dawley; Theophylline; Triazines; Triazoles | 2007 |
Purinergic modulation of glutamate release under ischemic-like conditions in the hippocampus.
Topics: Adenosine; Adenosine Triphosphate; Analgesics; Animals; Dose-Response Relationship, Drug; Glucose; Glutamic Acid; Hippocampus; Hypoxia; In Vitro Techniques; Ischemia; Male; Phenethylamines; Purinergic Agonists; Purinergic Antagonists; Pyrimidines; Rats; Rats, Wistar; Receptors, Purinergic; Sodium Channel Blockers; Tetrodotoxin; Triazines; Triazoles; Xanthines | 2007 |
Interaction of A2A adenosine and D2 dopamine receptors modulates corticostriatal glutamatergic transmission.
Topics: Adenine; Adenosine; Animals; Cerebral Cortex; Corpus Striatum; Dopamine Agonists; Excitatory Postsynaptic Potentials; Glutamic Acid; Male; Neurons; Organ Culture Techniques; Patch-Clamp Techniques; Phenethylamines; Quinpirole; Rats; Rats, Wistar; Receptor, Adenosine A2A; Receptors, Dopamine D2; Synaptic Transmission; Triazines; Triazoles | 2007 |
Adenosine A2A receptor agonists inhibit lipopolysaccharide-induced production of tumor necrosis factor-alpha by equine monocytes.
Topics: Adenosine; Adenosine A2 Receptor Agonists; Adenosine-5'-(N-ethylcarboxamide); Animals; Binding, Competitive; Cyclic AMP; Horses; Immunoenzyme Techniques; Lipopolysaccharides; Monocytes; Phenethylamines; Piperidines; Receptor, Adenosine A2A; Regression Analysis; Triazines; Triazoles; Tumor Necrosis Factor-alpha | 2008 |
Transient inhibition of astrocytogenesis in developing mouse brain following postnatal caffeine exposure.
Topics: Adenosine; Animals; Animals, Newborn; Apoptosis; Astrocytes; Behavior, Animal; Body Weight; Brain; Caffeine; Cell Differentiation; Cell Proliferation; Dose-Response Relationship, Drug; Glial Fibrillary Acidic Protein; Immunohistochemistry; Injections, Intraperitoneal; Mice; Microtubule-Associated Proteins; Models, Animal; Nerve Growth Factors; Organ Size; Phenethylamines; Pyrimidines; Receptor, Adenosine A2A; S100 Calcium Binding Protein beta Subunit; S100 Proteins; Synaptophysin; Time Factors; Triazoles | 2007 |
Adenosine A2A receptors are essential for long-term potentiation of NMDA-EPSCs at hippocampal mossy fiber synapses.
Topics: Adenosine; Adenosine A2 Receptor Agonists; Adenosine A2 Receptor Antagonists; Animals; Animals, Newborn; Calcium; Dose-Response Relationship, Radiation; Drug Interactions; Electric Stimulation; Enzyme Inhibitors; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; In Vitro Techniques; Long-Term Potentiation; Mice; Mice, Inbred C57BL; Microscopy, Electron, Transmission; Mossy Fibers, Hippocampal; N-Methylaspartate; Phenethylamines; Pyrimidines; Receptor, Adenosine A2A; Synapses; Triazoles | 2008 |
Enhancement of long-term potentiation by brain-derived neurotrophic factor requires adenosine A2A receptor activation by endogenous adenosine.
Topics: Adenosine; Adenosine A2 Receptor Agonists; Adenosine A2 Receptor Antagonists; Animals; Brain-Derived Neurotrophic Factor; Carbazoles; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Data Interpretation, Statistical; Excitatory Postsynaptic Potentials; Hippocampus; In Vitro Techniques; Indole Alkaloids; Isoquinolines; Long-Term Potentiation; Male; Neuroprotective Agents; Phenethylamines; Phosphorylation; Pyrimidines; Rats; Rats, Wistar; Receptor, Adenosine A2A; Sulfonamides; Triazoles | 2008 |
Human equilibrative nucleoside transporters 1 and 2 may be differentially modulated by A2B adenosine receptors in placenta microvascular endothelial cells from pre-eclampsia.
Topics: Adenosine; Adenosine A2 Receptor Agonists; Adenosine A2 Receptor Antagonists; Adult; Endothelial Cells; Equilibrative Nucleoside Transporter 1; Equilibrative-Nucleoside Transporter 2; Female; Gene Expression Regulation; Humans; Phenethylamines; Placenta; Pre-Eclampsia; Pregnancy; Receptor, Adenosine A2A; Receptor, Adenosine A2B; Triazines; Triazoles | 2008 |
Role of CYP epoxygenases in A2A AR-mediated relaxation using A2A AR-null and wild-type mice.
Topics: 8,11,14-Eicosatrienoic Acid; Acetylcholine; Adenosine; Adenosine-5'-(N-ethylcarboxamide); Amides; Amidines; Animals; Aorta; Arachidonic Acid; Chromatography, Liquid; Cytochrome P-450 CYP4A; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Cytochrome P450 Family 2; Dose-Response Relationship, Drug; Enzyme Inhibitors; Indomethacin; Male; Mice; Mice, Knockout; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Phenethylamines; Prostaglandin-Endoperoxide Synthases; Pyrimidines; Receptor, Adenosine A2A; Tandem Mass Spectrometry; Triazoles; Vasoconstriction; Vasoconstrictor Agents; Vasodilation; Vasodilator Agents | 2008 |
FGF acts as a co-transmitter through adenosine A(2A) receptor to regulate synaptic plasticity.
Topics: Adenosine; Adenosine A2 Receptor Agonists; Animals; Cell Differentiation; Cells, Cultured; Chlorocebus aethiops; Cyclic AMP; Embryo, Mammalian; Fibroblast Growth Factors; Hippocampus; Immunoprecipitation; In Vitro Techniques; Long-Term Potentiation; Mitogen-Activated Protein Kinase Kinases; Neurites; Neurons; Patch-Clamp Techniques; Phenethylamines; Rats; Rats, Sprague-Dawley; Receptor Protein-Tyrosine Kinases; Receptor, Adenosine A2A; Receptors, Fibroblast Growth Factor; Synapses; Transfection; Triazines; Triazoles; Two-Hybrid System Techniques | 2008 |
Modulation of gamma oscillations by endogenous adenosine through A1 and A2A receptors in the mouse hippocampus.
Topics: Adenosine; Adenosine A1 Receptor Antagonists; Adenosine A2 Receptor Antagonists; Analysis of Variance; Animals; Biological Clocks; Dose-Response Relationship, Drug; Evoked Potentials; Excitatory Amino Acid Agonists; Fourier Analysis; Hippocampus; Hypoxia; In Vitro Techniques; Kainic Acid; Male; Mice; Mice, Inbred C57BL; Phenethylamines; Receptor, Adenosine A1; Receptor, Adenosine A2A; Theophylline; Thioinosine; Time Factors; Triazines; Triazoles | 2009 |
Adenosine A(1) and A(2A) receptors in mouse prefrontal cortex modulate acetylcholine release and behavioral arousal.
Topics: Acetylcholine; Adenosine; Adenosine A1 Receptor Antagonists; Adenosine A2 Receptor Antagonists; Analysis of Variance; Animals; Arousal; Behavior, Animal; Caffeine; Chromatography, High Pressure Liquid; Electroencephalography; Electromyography; Male; Mice; Microdialysis; Phenethylamines; Phosphodiesterase Inhibitors; Prefrontal Cortex; Receptor, Adenosine A1; Receptors, Adenosine A2; Spectrum Analysis; Triazines; Triazoles; Xanthines | 2009 |
Activation of NTS A2a adenosine receptors differentially resets baroreflex control of renal vs. adrenal sympathetic nerve activity.
Topics: Adenosine; Adenosine A2 Receptor Agonists; Adenosine A2 Receptor Antagonists; Adrenal Glands; Animals; Antihypertensive Agents; Baroreflex; Blood Pressure; Heart Rate; Kidney; Male; Phenethylamines; Rats; Rats, Sprague-Dawley; Receptor, Adenosine A1; Receptor, Adenosine A2A; Solitary Nucleus; Sympathetic Nervous System; Theophylline; Triazines; Triazoles | 2009 |
Cardioprotection induced by adenosine A1 receptor agonists in a cardiac cell ischemia model involves cooperative activation of adenosine A2A and A2B receptors by endogenous adenosine.
Topics: Acetamides; Adenosine; Adenosine A1 Receptor Agonists; Adenosine A2 Receptor Agonists; Adenosine A2 Receptor Antagonists; Adenosine A3 Receptor Agonists; Adenosine A3 Receptor Antagonists; Aminopyridines; Animals; Apoptosis; Cardiotonic Agents; Cell Line; Cell Survival; Dihydropyridines; Imidazoles; Myocardial Ischemia; Phenethylamines; Purines; Rats; Triazines; Triazoles; Xanthines | 2009 |
The adenosine A2A receptor antagonist ZM241385 enhances neuronal survival after oxygen-glucose deprivation in rat CA1 hippocampal slices.
Topics: Adenosine; Adenosine A2 Receptor Antagonists; Animals; Astrocytes; Blotting, Western; Brain Ischemia; Cell Hypoxia; Cell Survival; Coloring Agents; Excitatory Postsynaptic Potentials; Glial Fibrillary Acidic Protein; Glucose; Hippocampus; Immunohistochemistry; In Vitro Techniques; Male; Neurons; Neuroprotective Agents; Oxygen; Phenethylamines; Propidium; Pyrazoles; Pyrimidines; Rats; Rats, Wistar; Receptor, Adenosine A2A; Staining and Labeling; Time Factors; Triazines; Triazoles | 2009 |
Differential regulation of HIF-1alpha isoforms in murine macrophages by TLR4 and adenosine A(2A) receptor agonists.
Topics: Adenosine; Adenosine A2 Receptor Agonists; Adenosine A2 Receptor Antagonists; Adenosine-5'-(N-ethylcarboxamide); Animals; Cells, Cultured; Drug Combinations; Female; Gene Expression Regulation; Genes, Reporter; Hypoxia-Inducible Factor 1, alpha Subunit; Lipopolysaccharides; Luciferases, Renilla; Macrophages, Peritoneal; Mice; Mice, Congenic; Mice, Inbred C57BL; NF-kappa B; Nitriles; Phenethylamines; Protein Isoforms; Purinergic P1 Receptor Agonists; RNA, Messenger; Sulfones; Toll-Like Receptor 4; Transfection; Triazines; Triazoles; Vascular Endothelial Growth Factor A | 2009 |
SAR of a series of inhaled A(2A) agonists and comparison of inhaled pharmacokinetics in a preclinical model with clinical pharmacokinetic data.
Topics: Adenosine; Adenosine A2 Receptor Agonists; Administration, Inhalation; Adolescent; Adult; Animals; Chemistry, Pharmaceutical; Drug Design; Humans; Inhibitory Concentration 50; Lung; Male; Middle Aged; Models, Chemical; Phenethylamines; Pulmonary Disease, Chronic Obstructive; Purines; Rats; Structure-Activity Relationship; Triazoles | 2009 |
Altered distribution and function of A2A adenosine receptors in the brain of WAG/Rij rats with genetic absence epilepsy, before and after appearance of the disease.
Topics: Adenosine; Age Factors; Analysis of Variance; Animals; Blotting, Western; Disease Models, Animal; Disease Progression; Electroencephalography; Epilepsy, Absence; Glutamic Acid; Immunohistochemistry; Male; MAP Kinase Signaling System; Microinjections; Phenethylamines; Pyrimidines; Rats; Receptor, Adenosine A2A; Somatosensory Cortex; Thalamus; Triazoles | 2009 |
Absence of adenosine-mediated aortic relaxation in A(2A) adenosine receptor knockout mice.
Topics: Acetylcholine; Adenosine; Adenosine-5'-(N-ethylcarboxamide); Aminopyridines; Animals; Aorta; Dose-Response Relationship, Drug; Endothelium, Vascular; Female; Flavins; Gene Expression Regulation; In Vitro Techniques; Male; Mice; Mice, Knockout; Phenethylamines; Pyrimidines; Receptor, Adenosine A1; Receptor, Adenosine A2A; Receptor, Adenosine A2B; Triazoles; Vasoconstriction; Vasoconstrictor Agents; Vasodilation; Vasodilator Agents; Xanthines | 2009 |
Role of adenosine A2 receptors in regulation of cerebral blood flow during induced hypotension.
Topics: Adenosine; Adenosine A2 Receptor Antagonists; Animals; Antihypertensive Agents; Blood Pressure; Cerebrovascular Circulation; Dipyridamole; Hypotension; Male; Mice; Mice, Knockout; Phenethylamines; Receptor, Adenosine A2A; Receptor, Adenosine A2B; Triazines; Triazoles; Vasodilation; Vasodilator Agents | 2010 |
Adenosine up-regulates vascular endothelial growth factor in human macrophages.
Topics: Adenosine; Adenosine A2 Receptor Agonists; Angiogenesis Inducing Agents; Cardiotonic Agents; Gene Expression; Humans; Hypoxia-Inducible Factor 1, alpha Subunit; Macrophages; Phenethylamines; Pyrimidines; Toll-Like Receptor 4; Triazoles; Up-Regulation; Vascular Endothelial Growth Factor A | 2010 |
Adenosine A(2)A receptor but not HIF-1 mediates Tyrosine hydroxylase induction in hypoxic PC12 cells.
Topics: Adenosine; Adenosine A2 Receptor Agonists; Adenosine A2 Receptor Antagonists; Animals; Aryl Hydrocarbon Receptor Nuclear Translocator; Cell Hypoxia; Cyclic AMP Response Element-Binding Protein; DNA; Hypoxia-Inducible Factor 1; Hypoxia-Inducible Factor 1, alpha Subunit; Mutation; PC12 Cells; Phenethylamines; Promoter Regions, Genetic; Rats; Receptor, Adenosine A2A; RNA, Messenger; Signal Transduction; Transcription, Genetic; Transfection; Triazines; Triazoles; Tyrosine 3-Monooxygenase | 2010 |
Ecto-5'-nucleotidase (CD73) attenuates allograft airway rejection through adenosine 2A receptor stimulation.
Topics: 5'-Nucleotidase; Adenosine; Adenosine A2 Receptor Agonists; Adenosine A2 Receptor Antagonists; Animals; Bronchiolitis Obliterans; CD3 Complex; Chromatography, Liquid; Gene Expression; Graft Rejection; Interferon-gamma; Interleukin-2; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Phenethylamines; Pyrimidines; Receptor, Adenosine A2A; Reverse Transcriptase Polymerase Chain Reaction; T-Lymphocytes; Tandem Mass Spectrometry; Trachea; Transplantation, Homologous; Triazoles | 2010 |
Activation of adenosine A2A receptor attenuates inflammatory response in a rat model of small-for-size liver transplantation.
Topics: Adenosine; Adenosine A2 Receptor Agonists; Adenosine A2 Receptor Antagonists; Alanine Transaminase; Animals; Chemokine CXCL2; Cytokines; Enzyme-Linked Immunosorbent Assay; Inflammation; Intercellular Adhesion Molecule-1; Liver; Liver Transplantation; Male; NF-kappa B; Organ Size; Peroxidase; Phenethylamines; Phosphorylation; Rats; Rats, Inbred Lew; Receptor, Adenosine A2A; Triazines; Triazoles; Tumor Necrosis Factor-alpha | 2010 |
Peripheral adenosine A2A receptors are involved in carrageenan-induced mechanical hyperalgesia in mice.
Topics: Adenosine; Adenosine A2 Receptor Agonists; Adenosine A2 Receptor Antagonists; Animals; Carrageenan; Female; Ganglia, Spinal; Hyperalgesia; Inflammation; Injections, Intraperitoneal; Injections, Subcutaneous; Male; Mice; Mice, Knockout; Pain; Pain Threshold; Phenethylamines; Receptor, Adenosine A2A; Sex Characteristics; Triazines; Triazoles | 2010 |
Novel 8-(furan-2-yl)-3-benzyl thiazolo [5,4-e][1,2,4] triazolo [1,5-c] pyrimidine-2(3H)-thione as selective adenosine A(2A) receptor antagonist.
Topics: Acridines; Adenosine; Adenosine A2 Receptor Agonists; Adenosine A2 Receptor Antagonists; Animals; Cell Line, Transformed; Chloroquinolinols; Corpus Striatum; Cyclic AMP; Dopamine Antagonists; Dose-Response Relationship, Drug; Humans; Mice; Models, Molecular; Phenethylamines; Protein Binding; Pyrimidines; Receptors, Adenosine A2; Time Factors; Triazoles; Tritium | 2011 |
Contribution of adenosine A(2A) and A(2B) receptors to ischemic coronary dilation: role of K(V) and K(ATP) channels.
Topics: 4-Aminopyridine; Adenosine; Adenosine A2 Receptor Agonists; Adenosine A2 Receptor Antagonists; Animals; Coronary Circulation; Disease Models, Animal; Dogs; Flavins; Glyburide; Hyperemia; KATP Channels; Male; Myocardial Ischemia; Phenethylamines; Potassium Channel Blockers; Potassium Channels, Voltage-Gated; Pyrimidines; Receptor, Adenosine A2A; Receptor, Adenosine A2B; Triazoles; Vasodilation | 2010 |
Static magnetic field exposure reproduces cellular effects of the Parkinson's disease drug candidate ZM241385.
Topics: Adenosine; Adenosine A2 Receptor Agonists; Adenosine A2 Receptor Antagonists; Adenosine Triphosphate; Analysis of Variance; Animals; Blotting, Western; Calcium; Cell Proliferation; Cyclic AMP; Iron; Magnetic Field Therapy; Magnetics; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Neurites; Parkinson Disease; PC12 Cells; Phenethylamines; Phosphorylation; Rats; Receptor, Adenosine A2A; Triazines; Triazoles | 2010 |
Selective adenosine A2A receptor agonists and antagonists protect against spinal cord injury through peripheral and central effects.
Topics: Adenosine; Adenosine A2 Receptor Agonists; Adenosine A2 Receptor Antagonists; Animals; Inflammation; Infusion Pumps, Implantable; JNK Mitogen-Activated Protein Kinases; Male; Mice; Motor Activity; Phenethylamines; Pyrimidines; Spinal Cord; Spinal Cord Injuries; Triazoles | 2011 |
Adenosine A(2A) receptor activation prevents progressive kidney fibrosis in a model of immune-associated chronic inflammation.
Topics: Adenosine; Adenosine A2 Receptor Agonists; Adenosine A2 Receptor Antagonists; Animals; Anti-Inflammatory Agents; Autoantibodies; Disease Models, Animal; Extracellular Matrix Proteins; Fibrosis; Glomerulonephritis; Inflammation Mediators; Kidney; Macrophages; Male; Phenethylamines; Rats; Rats, Inbred WKY; Receptor, Adenosine A2A; Severity of Illness Index; Time Factors; Triazines; Triazoles | 2011 |
The effect of A(2A) adenosine receptor activation on C-C chemokine receptor 7 expression in human THP1 macrophages during inflammation.
Topics: Adenosine; Adenosine A2 Receptor Agonists; Adenosine A2 Receptor Antagonists; Cell Line; Cell Movement; Chemokine CCL21; Humans; Inflammation; Macrophages; Phenethylamines; Receptors, Adenosine A2; Receptors, CCR7; RNA, Messenger; Triazines; Triazoles | 2012 |
Distinctive immunoregulatory effects of adenosine on T cells of older humans.
Topics: Adenine; Adenosine; Adenosine A2 Receptor Agonists; Adenosine A2 Receptor Antagonists; Adult; Age Factors; Aged; Aged, 80 and over; Antigens, CD; Apyrase; CD28 Antigens; Cells, Cultured; Chemotaxis; Cytokines; Dose-Response Relationship, Drug; Female; Flow Cytometry; Humans; Male; Middle Aged; Phenethylamines; Pyrimidines; T-Lymphocytes; Triazoles; Young Adult | 2012 |
Adenosine A2A receptor modulates vascular response in soluble epoxide hydrolase-null mice through CYP-epoxygenases and PPARγ.
Topics: 8,11,14-Eicosatrienoic Acid; Adamantane; Adenosine; Adenosine A2 Receptor Agonists; Adenosine A2 Receptor Antagonists; Adenosine-5'-(N-ethylcarboxamide); Animals; Benzamides; Benzoates; Butyrates; Enzyme Inhibitors; Epoxide Hydrolases; Female; Gene Silencing; Lauric Acids; Male; Mice; NG-Nitroarginine Methyl Ester; Oxygenases; Phenethylamines; Phenylurea Compounds; PPAR gamma; Pyridines; Pyrimidines; Receptor, Adenosine A2A; Triazines; Triazoles; Urea; Vasodilation; Vasodilator Agents | 2013 |
Adenosine 2A receptor modulates inflammation and phenotype in experimental abdominal aortic aneurysms.
Topics: Adenosine; Adenosine A2 Receptor Agonists; Adenosine A2 Receptor Antagonists; Animals; Aortic Aneurysm, Abdominal; CD4-Positive T-Lymphocytes; Cytokines; Humans; Inflammation; Male; Matrix Metalloproteinase 9; Mice; Mice, Inbred C57BL; Mice, Knockout; Pancreatic Elastase; Phenethylamines; Phenotype; Receptors, Adenosine A2; Triazines; Triazoles | 2013 |
Role of adenosine A2A receptor in organ-specific vascular reactivity following hemorrhagic shock in rats.
Topics: Adenosine; Adenosine A2 Receptor Agonists; Adenosine A2 Receptor Antagonists; Animals; Aorta, Thoracic; Female; Femoral Artery; Hemodynamics; Male; Mesenteric Artery, Superior; Middle Cerebral Artery; Models, Animal; Phenethylamines; Pulmonary Artery; Pyrimidines; Rats; Rats, Sprague-Dawley; Receptor, Adenosine A2A; Renal Artery; Shock, Hemorrhagic; Survival Rate; Triazoles | 2013 |
Adenosine A(2A) receptors regulate the activity of sleep regulatory GABAergic neurons in the preoptic hypothalamus.
Topics: Adenosine; Adenosine A2 Receptor Agonists; Adenosine A2 Receptor Antagonists; Animals; GABAergic Neurons; Hypothalamus; Infusions, Intraventricular; Male; Microinjections; Models, Animal; Phenethylamines; Preoptic Area; Proto-Oncogene Proteins c-fos; Rats; Rats, Sprague-Dawley; Receptor, Adenosine A2A; Sleep; Triazines; Triazoles | 2013 |
Functional interaction between pre-synaptic α6β2-containing nicotinic and adenosine A2A receptors in the control of dopamine release in the rat striatum.
Topics: Adenosine; Adenosine A2 Receptor Agonists; Adenosine A2 Receptor Antagonists; Animals; Corpus Striatum; Dopamine; Gene Expression Regulation; Male; Motor Skills; Nicotine; Phenethylamines; Presynaptic Terminals; Rats; Rats, Wistar; Receptor, Adenosine A2A; Receptors, Nicotinic; Synaptosomes; Triazines; Triazoles | 2013 |
Adenosine A₂A receptors inhibit delayed rectifier potassium currents and cell differentiation in primary purified oligodendrocyte cultures.
Topics: Adenosine; Adenosine A2 Receptor Agonists; Adenosine A2 Receptor Antagonists; Animals; Cell Differentiation; Cell Proliferation; Delayed Rectifier Potassium Channels; Dose-Response Relationship, Drug; Electric Conductivity; Membrane Potentials; Neural Inhibition; Oligodendroglia; Phenethylamines; Potassium; Primary Cell Culture; Pyrimidines; Rats; Receptor, Adenosine A2A; Stem Cells; Triazoles | 2013 |
Adenosine A2A receptor contributes to ischemic brain damage in newborn piglet.
Topics: Adenosine; Adenosine A2 Receptor Agonists; Adenosine A2 Receptor Antagonists; Animals; Animals, Newborn; Blood Flow Velocity; Cerebrovascular Circulation; Corpus Striatum; Disease Models, Animal; Hypoxia-Ischemia, Brain; Immunohistochemistry; Laser-Doppler Flowmetry; Male; Neurons; Oxidative Stress; Phenethylamines; Pyrimidines; Receptor, Adenosine A2A; Sus scrofa; Triazoles | 2013 |
The stimulation of adenosine A2A receptors ameliorates the pathological phenotype of fibroblasts from Niemann-Pick type C patients.
Topics: Adenosine; Adenosine A2 Receptor Agonists; Adenosine A2 Receptor Antagonists; Calcium; Case-Control Studies; Cell Line; Cholesterol; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Electron Transport Complex IV; Extracellular Signal-Regulated MAP Kinases; Female; Fibroblasts; Humans; Lysosomes; Male; Membrane Potential, Mitochondrial; Mitochondria; Niemann-Pick Disease, Type C; Phenethylamines; Phenotype; Receptor, Adenosine A2A; Triazines; Triazoles | 2013 |
Nucleus tractus solitarii A(2a) adenosine receptors inhibit cardiopulmonary chemoreflex control of sympathetic outputs.
Topics: Adenosine; Adrenal Glands; Animals; Biguanides; Blood Pressure; Chemoreceptor Cells; Heart Atria; Heart Conduction System; Heart Rate; Hypotension; Kidney; Lumbosacral Region; Male; Microinjections; Models, Neurological; Phenethylamines; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, alpha-2; Reflex; Serotonin 5-HT3 Receptor Agonists; Solitary Nucleus; Sympathetic Nervous System; Triazines; Triazoles | 2014 |
Selective inhibition of KCa3.1 channels mediates adenosine regulation of the motility of human T cells.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Adenosine; Calcium; Calcium Channel Blockers; Cell Movement; Cells, Cultured; Cyclic AMP-Dependent Protein Kinase Type I; Female; Humans; Immunologic Surveillance; Intercellular Adhesion Molecule-1; Interleukin-2; Intermediate-Conductance Calcium-Activated Potassium Channels; Ion Transport; Kv1.3 Potassium Channel; Lymphocyte Activation; Male; Patch-Clamp Techniques; Phenethylamines; Protein Serine-Threonine Kinases; Pyrazoles; Pyrimidines; Receptor, Adenosine A2A; T-Lymphocytes; Triazoles; TRPM Cation Channels | 2013 |
Antagonistic interaction between adenosine A2A receptors and Na+/K+-ATPase-α2 controlling glutamate uptake in astrocytes.
Topics: Adenosine; Adenosine A2 Receptor Agonists; Adenosine A2 Receptor Antagonists; Analysis of Variance; Animals; Aspartic Acid; Astrocytes; Glial Fibrillary Acidic Protein; Glutamic Acid; Immunoprecipitation; Male; Mice; Mice, Inbred C57BL; Mice, Transgenic; Ouabain; Phenethylamines; Pyrimidines; Receptor, Adenosine A2A; Sodium-Potassium-Exchanging ATPase; Subcellular Fractions; Triazoles; Tritium | 2013 |
Mechanisms involved in increased sensitivity to adenosine A(2A) receptor activation and hypoxia-induced vasodilatation in porcine coronary arteries.
Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Coronary Vessels; Cyclic AMP; Dinoprost; HSP20 Heat-Shock Proteins; Hypoxia; In Vitro Techniques; Oxygen; Phenethylamines; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Receptors, Purinergic P1; Swine; Triazines; Triazoles; Vasodilation | 2014 |
Adenosine A(2A) Receptors as novel upstream regulators of BDNF-mediated attenuation of hippocampal Long-Term Depression (LTD).
Topics: Adenosine; Adenosine A2 Receptor Agonists; Adenosine A2 Receptor Antagonists; Adenosine Deaminase; Adenylyl Cyclases; Animals; Brain-Derived Neurotrophic Factor; CA1 Region, Hippocampal; Cyclic AMP-Dependent Protein Kinases; Electric Stimulation; Enzyme Inhibitors; Extracellular Space; In Vitro Techniques; Long-Term Synaptic Depression; Phenethylamines; Pyrimidines; Rats; Rats, Wistar; Receptor, Adenosine A2A; Receptor, trkB; Triazoles | 2014 |
Extracellular adenosine controls NKT-cell-dependent hepatitis induction.
Topics: Adenosine; Adenosine A2 Receptor Agonists; Adenosine A2 Receptor Antagonists; Animals; Cells, Cultured; Concanavalin A; Flow Cytometry; Galactosylceramides; Hepatitis, Animal; Interferon-gamma; Liver; Mice; Mice, Inbred C57BL; Mice, Knockout; Natural Killer T-Cells; Phenethylamines; Receptor, Adenosine A2A; Triazines; Triazoles; Tumor Necrosis Factor-alpha | 2014 |
Histamine H3 receptor activation counteracts adenosine A2A receptor-mediated enhancement of depolarization-evoked [3H]-GABA release from rat globus pallidus synaptosomes.
Topics: Adenosine; Adenosine A2 Receptor Agonists; Adenosine A2 Receptor Antagonists; Animals; Biphenyl Compounds; gamma-Aminobutyric Acid; Globus Pallidus; Histamine Agonists; Histamine H3 Antagonists; Imidazoles; Male; Membrane Potentials; Nitriles; Phenethylamines; Piperidines; Potassium; Pyrrolidines; Rats, Wistar; Receptor, Adenosine A2A; Receptors, Histamine H3; Synaptosomes; Thiourea; Triazines; Triazoles; Tritium | 2014 |
On the role of adenosine (A)₂A receptors in cocaine-induced reward: a pharmacological and neurochemical analysis in rats.
Topics: Adenosine; Adenosine A2 Receptor Agonists; Animals; Basal Forebrain; Behavior, Animal; Cocaine; Cocaine-Related Disorders; Dopamine; gamma-Aminobutyric Acid; Glutamic Acid; Male; Nucleus Accumbens; Phenethylamines; Purines; Pyrimidines; Rats; Rats, Wistar; Receptor, Adenosine A2A; Reinforcement, Psychology; Reward; Self Administration; Triazoles | 2015 |
Expression of CD73 and A2A receptors in cells from subjects with obesity and type 2 diabetes mellitus.
Topics: 5'-Nucleotidase; Adenosine; Adult; Antigens, CD; Apoptosis; Apyrase; Body Mass Index; CD8-Positive T-Lymphocytes; Diabetes Mellitus, Type 2; Gene Expression Regulation; GPI-Linked Proteins; Humans; Inflammation; Lymphocyte Subsets; Lymphocytes; Obesity; Phenethylamines; Receptor, Adenosine A2A; Triazines; Triazoles | 2015 |
Adenosine A(2A) receptors are necessary and sufficient to trigger memory impairment in adult mice.
Topics: Adenosine; Animals; Avoidance Learning; Dose-Response Relationship, Drug; Infusions, Intraventricular; Locomotion; Male; Maze Learning; Memory Disorders; Memory, Short-Term; Mice; Phenethylamines; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Pyrimidines; Receptor, Adenosine A1; Receptor, Adenosine A2A; Recognition, Psychology; Scopolamine; Triazoles; Xanthines | 2015 |
Effect of adenosine system in the action of oseltamivir on behavior in mice.
Topics: Adenosine; Adenosine A1 Receptor Antagonists; Adenosine A2 Receptor Agonists; Adenosine A2 Receptor Antagonists; Animals; Antiviral Agents; Behavior, Animal; Caffeine; Dose-Response Relationship, Drug; Drug Interactions; Male; Mice; Neuraminidase; Oseltamivir; Phenethylamines; Pyrimidines; Receptors, Adenosine A2; Triazoles; Walking | 2015 |
Evaluation of the expression and function of the P2X7 receptor and ART1 in human regulatory T-cell subsets.
Topics: Adenosine; Adenosine A2 Receptor Agonists; Adenosine A2 Receptor Antagonists; Adenosine Triphosphate; Adolescent; ADP Ribose Transferases; Adult; Antigens, CD; Apyrase; Cell Death; Cell Proliferation; Female; Gene Expression Regulation; GPI-Linked Proteins; Humans; Immunophenotyping; L-Selectin; Male; NAD; Phenethylamines; Primary Cell Culture; Receptors, Adenosine A2; Receptors, Purinergic P2X7; Signal Transduction; T-Lymphocyte Subsets; Triazines; Triazoles | 2016 |
Adenosine A2A receptor activation is determinant for BDNF actions upon GABA and glutamate release from rat hippocampal synaptosomes.
Topics: Adenosine; Adenosine A2 Receptor Agonists; Adenosine A2 Receptor Antagonists; Animals; Brain-Derived Neurotrophic Factor; gamma-Aminobutyric Acid; Glutamic Acid; Hippocampus; In Vitro Techniques; Phenethylamines; Potassium; Pyrimidines; Rats; Rats, Wistar; Receptor, Adenosine A2A; Synaptosomes; Triazoles | 2015 |
Mechanisms of the adenosine A2A receptor-induced sensitization of esophageal C fibers.
Topics: Adenosine; Adenosine A2 Receptor Agonists; Animals; Dose-Response Relationship, Drug; Esophagus; Guinea Pigs; In Vitro Techniques; Isoquinolines; Muscle Contraction; Nerve Endings; Nerve Fibers, Unmyelinated; Neuroprotective Agents; Nodose Ganglion; Patch-Clamp Techniques; Phenethylamines; Protein Kinase Inhibitors; Purinergic P2X Receptor Agonists; Pyrimidines; Receptor, Adenosine A2A; Sulfonamides; Transient Receptor Potential Channels; Triazoles; Vagus Nerve | 2016 |
Adenosine A
Topics: Adenosine; Adenosine A2 Receptor Agonists; Adenosine A2 Receptor Antagonists; Analysis of Variance; Animals; Dependovirus; Dose-Response Relationship, Drug; Electroencephalography; Electromyography; Luminescent Proteins; Male; Mice; Mice, Inbred C57BL; Mice, Transgenic; Neural Inhibition; Olfactory Bulb; Patch-Clamp Techniques; Phenethylamines; Proto-Oncogene Proteins c-fos; Pyrimidines; Rats; Rats, Sprague-Dawley; Receptor, Adenosine A2A; RNA, Small Interfering; Sleep, REM; Transduction, Genetic; Triazoles | 2017 |
Adenosine A
Topics: Adenosine; Adenosine A2 Receptor Agonists; Adult; Aged; Animals; Brain Injuries, Traumatic; Cognitive Dysfunction; Disease Models, Animal; Female; Glycogen Synthase Kinase 3 beta; Glycogen Synthase Kinases; Hippocampus; Humans; Indoles; Isoquinolines; Male; Maleimides; Mice; Mice, Knockout; Middle Aged; Neurons; Phenethylamines; Phosphorylation; Protein Kinase Inhibitors; Receptor, Adenosine A2A; Signal Transduction; Sulfonamides; tau Proteins; Triazines; Triazoles | 2017 |
Nucleus accumbens mediates the pronociceptive effect of sleep deprivation: the role of adenosine A2A and dopamine D2 receptors.
Topics: Adenosine; Adenosine A2 Receptor Agonists; Animals; Male; Motor Activity; Nociception; Nucleus Accumbens; Pain; Phenethylamines; Piribedil; Purinergic P1 Receptor Antagonists; Pyrimidines; Rats; Rats, Wistar; Receptor, Adenosine A2A; Receptors, Dopamine D2; Sleep Deprivation; Sleep, REM; Triazoles | 2018 |
Cystatin F involvement in adenosine A
Topics: Adenosine; Adenosine A2 Receptor Agonists; Adenosine A2 Receptor Antagonists; Analysis of Variance; Animals; Cell Hypoxia; Cell Line; Cell Survival; Cyclic AMP Response Element-Binding Protein; Cyclic AMP-Dependent Protein Kinases; Cystatins; Cytokines; Gene Knockdown Techniques; MAP Kinase Signaling System; Mice; Microglia; Phenethylamines; Protein Kinase C; Pyrimidines; Receptor, Adenosine A2A; RNA, Small Interfering; Signal Transduction; Transfection; Triazoles | 2018 |
Ischemia postconditioning protects dermal microvascular endothelial cells of rabbit epigastric skin flaps against apoptosis via adenosine A2a receptors.
Topics: Abdomen; Adenosine; Adenosine A2 Receptor Agonists; Adenosine A2 Receptor Antagonists; Animals; Apoptosis; Dermis; Endothelial Cells; Ischemic Postconditioning; Models, Animal; Phenethylamines; Rabbits; Surgical Flaps; Triazines; Triazoles | 2019 |
Time-Dependent Bidirectional Neuroprotection by Adenosine 2A Receptor in Experimental Traumatic Brain Injury.
Topics: Adenosine; Animals; Brain Injuries; Brain Injuries, Traumatic; Disease Models, Animal; Male; Neuroprotection; Neuroprotective Agents; Phenethylamines; Pyrimidines; Rats, Wistar; Receptors, Purinergic P1; Signal Transduction; Time Factors; Triazoles | 2019 |
Activation of adenosine A2a receptor accelerates and A2a receptor antagonist reduces intermittent hypoxia induced PC12 cell injury via PKC-KATP pathway.
Topics: Adenosine; Adenosine A2 Receptor Agonists; Adenosine A2 Receptor Antagonists; Adenosine Triphosphate; Animals; Cell Hypoxia; KATP Channels; PC12 Cells; Phenethylamines; Potassium Channels; Protein Kinase C; Pyrimidines; Random Allocation; Rats; Receptor, Adenosine A2A; Signal Transduction; Sulfonylurea Receptors; Triazoles | 2019 |
Caffeine Exacerbates Postictal Hypoxia.
Topics: Adenosine; Animals; CA1 Region, Hippocampal; Caffeine; Dose-Response Relationship, Drug; Hypoxia; Kindling, Neurologic; Male; Oxygen; Phenethylamines; Pyrimidines; Rats; Receptors, Adenosine A2; Seizures; Triazoles | 2019 |