triazoles has been researched along with 1,3-dipropyl-8-cyclopentylxanthine in 154 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 31 (20.13) | 18.2507 |
| 2000's | 100 (64.94) | 29.6817 |
| 2010's | 22 (14.29) | 24.3611 |
| 2020's | 1 (0.65) | 2.80 |
| Authors | Studies |
|---|---|
| O'Regan, MH; Perkins, LM; Phillis, JW; Simpson, RE | 1 |
| Adén, U; Fredholm, BB; Johansson, B; Lindström, K; Svenningsson, P | 1 |
| Barraco, RA; Phillis, JW | 1 |
| Bourguignon, JJ; Griebel, G; Misslin, R; Remmy, D; Saffroy-Spittler, M; Vogel, E | 1 |
| Behnke, N; Müller, W; Neumann, J; Schmitz, W; Scholz, H; Stein, B | 1 |
| Karasawa, A; Kishibayashi, N; Suzuki, M; Tomaru, A | 1 |
| Amoroso, S; Annunziato, L; Di Renzo, G; Iannotti, E; Saggese, ML | 1 |
| Jarvis, JE; Reeves, JJ; Sheehan, MJ; Strong, P | 1 |
| Becker, BF; Raschke, P | 1 |
| Schmitz, W; Scholz, H; Seeland, C; Stein, B | 1 |
| di Chiara, G; Morelli, M; Pinna, A; Wardas, J | 1 |
| Anderson, GF; Barraco, RA; Helfman, CC | 1 |
| De Sarro, A; De Sarro, G; Donato Di Paola, E; Falconi, U; Ferreri, G | 1 |
| Dixon, AK; Richardson, PJ; Widdowson, L | 1 |
| Adén, U; Bona, E; Fredholm, BB; Gilland, E; Hagberg, H | 1 |
| McGrath, JC; Moore, FP; Thomson, NC | 1 |
| Belardinelli, L; Dennis, DM; Lozza, G; Monopoli, A; Olsson, RA; Ongini, E; Shryock, JC; Snowdy, S; Zhang, Y | 1 |
| Jones, PA; Smith, RA; Stone, TW | 1 |
| Fenu, S; Morelli, M | 1 |
| Bryan, PT; Marshall, JM | 1 |
| Cutler, BS; Dobson, JG; Fenton, RA; Li, Jm; Peyton, BD; Powell, CC; Wheeler, HB | 1 |
| Dionisotti, S; Fredholm, BB; Gessi, S; Irenius, E; Ongini, E | 1 |
| Ferré, S; Fredholm, BB; Fuxe, K; Lillrank, SM; Lipska, BK; Weinberger, DR | 1 |
| Fredholm, BB; Johansson, B; Kuzmin, A; Zvartau, EE | 1 |
| Kopf, SR; Melani, A; Pedata, F; Pepeu, G | 1 |
| Bordoni, F; Corradetti, R; Latini, S; Pedata, F; Pepeu, G | 1 |
| Enyeart, JJ; Xu, L | 1 |
| Brunsden, AM; Grundy, D | 1 |
| Davie, CS; Everitt, DE; Standen, NB | 1 |
| Fei, Q; Loutzenhiser, R; Parker, M; Tang, L | 1 |
| Cunha, RA; Lopes, LV; Ribeiro, JA | 1 |
| Costentin, J; El Yacoubi, M; Ledent, C; Parmentier, M; Vaugeois, JM | 2 |
| Costentin, J; El Yacoubi, M; Ledent, C; Ménard, JF; Parmentier, M; Vaugeois, JM | 1 |
| Cunha, RA; Pereira, MF; Ribeiro, JA | 1 |
| Bar-Yehuda, S; Barer, F; Farbstein, T; Fishman, P; Ohana, G | 1 |
| Abebe, W; Mozaffari, MS; Warren, BK | 1 |
| Clark, KL; Guyton, RA; Nakamura, M; Velez, DV; Vinten-Johansen, J; Zhao, ZQ | 1 |
| Agostinho, P; Cunha, RA; Melo, J; Oliveira, CR; Rego, AC | 1 |
| Matsuki, N; Nakazawa, K; Ohno, Y; Sato, K | 1 |
| Fredholm, BB; Hall, H; Kull, B; Svenningsson, P | 1 |
| Cunha, RA; Hernández, MD; Miras-Portugal, MT; Pereira, MF; Pintor, J; Ribeiro, JA | 1 |
| Brand, A; Eschke, D; Nieber, K; Vissiennon, Z | 1 |
| Koos, BJ; Maeda, T | 2 |
| Beilstein, M; Castagnoli, K; Castagnoli, N; Chen, JF; Petzer, JP; Schwarzschild, MA; Sonsalla, PK; Staal, R; Xu, K; Xu, YH | 1 |
| Jan, C; Koos, BJ; Maeda, T | 1 |
| Bernardi, G; Calabresi, P; Centonze, D; Pisani, A; Saulle, E | 1 |
| Baraldi, PG; Borea, PA; Ferrari, D; Gessi, S; Leung, E; Merighi, S; Morelli, A; Spalluto, G; Varani, K | 1 |
| Hamann, M; Richter, A | 1 |
| Breschi, MC; Calderone, V; Martinotti, E; Nieri, P | 1 |
| Culmsee, C; Kemp, BE; Mattson, MP; Monnig, J | 1 |
| Crum, AV; Meno, JR; Winn, HR | 1 |
| Edmunds, NJ; Marshall, JM | 1 |
| Baldwin, SA; Cass, CE; Duszyk, M; Man, SF; Ng, AM; Sawicka, J; Szkotak, AJ; Young, JD | 1 |
| Borea, PA; Cattabriga, E; Gessi, S; Iannotta, V; Leung, E; Merighi, S; Ulouglu, C; Varani, K | 1 |
| Furue, H; Kumamoto, E; Lao, LJ; Luo, C; Yoshimura, M | 1 |
| Ashton, K; Berr, SS; Cerniway, RJ; Harrison, GJ; Headrick, JP; Paul Matherne, G; Peart, J; Regan, S | 1 |
| Fredholm, BB; Schulte, G | 1 |
| Jan, C; Koos, BJ; Lopez, G; Maeda, T | 1 |
| Bonfanti, A; Marchi, M; Monopoli, A; Ongini, E; Raiteri, L; Raiteri, M; Risso, F; Vallarino, A | 1 |
| Cunha, RA; Fredholm, BB; Kull, B; Lopes, LV; Ribeiro, JA | 1 |
| Belem, PC; Chen, JF; Cronstein, B; Elson, G; Fink, JS; Jacobson, M; Leibovich, SJ; Montesinos, C; Pinhal-Enfield, G; Ramanathan, M; Rosania, A; Schwarzschild, MA | 1 |
| Gao, ZG; IJzerman, AP; Jacobson, KA; Kim, SG; Melman, N; Soltysiak, KA | 1 |
| Acquas, E; Di Chiara, G; Tanda, G | 1 |
| Le Crom, S; Prou, D; Vernier, P | 1 |
| Brackenborough, KT; Duffy, C; Hagan, RM; Jones, SA; Morgan, PF; Pratt, GD; Sargent, RS; Southam, E; Stratton, SC | 1 |
| Cunha, RA; Oliveira, CR; Rebola, N | 1 |
| Diniz, C; Gonçalves, J; Leal, S | 1 |
| Almeida, CG; Cunha, RA; de Mendonça, A; Ribeiro, JA | 1 |
| Antoniou, K; Ferré, S; Fuxe, K; Goldberg, SR; Justinova, Z; Karcz-Kubicha, M; Müller, CE; Pezzola, A; Popoli, P; Quarta, D; Reggio, R; Solinas, M; Terasmaa, A | 1 |
| Saccone, GT; Toouli, J; Woods, CM | 1 |
| Cunha, RA; de Mendonca, A; Oliveira, CR; Rebola, N; Ribeiro, JA; Sebastião, AM | 1 |
| O'Regan, MH; Phillis, JW | 1 |
| Corradetti, R; Latini, S; Pedata, F; Pugliese, AM | 1 |
| Goulart, EC; Kaster, MP; Rodrigues, AL; Rosa, AO; Rosso, MM; Santos, AR | 1 |
| Furuta, S; Honma, I; Kumagai, M; Miyazaki, S; Onodera, K; Sakurada, S; Sato, T | 1 |
| Kwok, YN; Yip, L | 1 |
| Bremer, HC; Elsner, P; Girolomoni, G; Herouy, Y; Idzko, M; Mockenhaupt, M; Norgauer, J; Panther, E; Sorichter, S; Windisch, W | 1 |
| Chen, JF; Cunha, RA; Fredholm, BB; Halldner, L; Johansson, B; Ledent, C; Lopes, LV; Rebola, N | 1 |
| Dziubina, A; Gołembiowska, K | 1 |
| Batista, LC; Prediger, RD; Takahashi, RN | 1 |
| Connole, L; Harkin, A; Maginn, M | 1 |
| Bohorquez, F; Kawasaki, Y; Kim, YH; Koos, BJ | 1 |
| Briones, R; Donoso, MV; Huidobro-Toro, JP; López, R; Miranda, R | 1 |
| Ballard-Croft, C; Keith, BJ; Kristo, G; Lasley, RD; Mentzer, RM; Reid, EA; Yoshimura, Y | 1 |
| Alfaro, TM; Cunha, RA; Oliveira, CR; Rebola, N; Rodrigues, RJ | 1 |
| Ackley, MA; Baldwin, SA; King, AE | 1 |
| Prediger, RD; Takahashi, RN | 1 |
| Hikichi, T; Kawahara, A; Kitaya, N; Mori, F; Takahashi, J; Yoshida, A | 1 |
| Fernandes, D; Prediger, RD; Takahashi, RN | 1 |
| Bonan, CD; Cammarota, M; Izquierdo, I; Pereira, GS; Rossato, JI; Sarkis, JJ | 1 |
| Sladek, CD; Song, Z | 1 |
| Amerson, BS; Guyton, RA; Halkos, ME; Headrick, JP; Kerendi, F; Kin, H; Lofye, MT; Vinten-Johansen, J; Zatta, AJ; Zhao, ZQ | 1 |
| Cavalheiro, EA; da Silva Fernandes, MJ; Doná, F; Ferreira, AT; Vianna, EP | 1 |
| Almeida, T; Cunha, RA; Oliveira, CR; Richardson, PJ; Rodrigues, RJ | 1 |
| Fredholm, BB; Gimenez, L; Johansson, B; Kuzmin, A; Ogren, SO | 1 |
| Marshall, JM; Ray, CJ | 1 |
| Gao, ZG; Jacobson, KA; Moro, S; Spalluto, G | 1 |
| Alexander, SP; Beckett, SR; Harper, LK; Marsden, CA; McCreary, AC | 1 |
| Greengard, P; Higashi, H; Kuroiwa, M; Nishi, A; Shuto, T; Snyder, GL; Sotogaku, N; Tanaka, M; Yabuuchi, K | 1 |
| Chuaychoo, B; Kollarik, M; Lee, MG; Pullmann, R; Undem, BJ | 1 |
| Canas, PM; Cunha, GM; Cunha, RA; Oliveira, CR | 1 |
| Conde, SV; Gonzalez, C; Obeso, A; Rigual, R; Rocher, A; Vicario, I | 1 |
| Mulè, F; Serio, R; Zizzo, MG | 1 |
| Borsini, F; Carminati, P; Di Cesare, MA; Ghirardi, O; Minetti, P; Stasi, MA; Varani, K; Vincenzi, F | 1 |
| Cunha-Reis, D; Fontinha, BM; Ribeiro, JA; Sebastião, AM | 1 |
| Beukers, MW; Blad, CC; Brouwer, J; den Dulk, H; Ijzerman, AP; Li, Q; Ye, K | 1 |
| Bairam, A; Kinkead, R; Montandon, G | 1 |
| Albasanz, JL; Castillo, CA; Fernández, M; Martín, M | 1 |
| Adams, CL; Cowen, MS; Lawrence, AJ; Short, JL | 1 |
| Battastini, AM; Bavaresco, L; Bernardi, A; Delgado-Cañedo, A; Jacques-Silva, MC; Lenz, G; Wink, MR | 1 |
| Hamano, R; Iwagaki, H; Kanke, T; Liu, K; Nishibori, M; Sendo, T; Takahashi, HK; Tanaka, N; Yoshino, T | 1 |
| Baranyi, M; Illes, P; Sperlágh, B; Vizi, ES; Zsilla, G | 1 |
| Albasanz, JL; Barrachina, M; Ferrer, I; Martín, M; Perez, S | 1 |
| Binfaré, RW; Budni, J; Lobato, KR; Rodrigues, AL; Rosa, AO; Santos, AR | 1 |
| Coskun, C; Mutlu, D; Savci, V; Suzer, O; Yalcin, M; Yilmaz, MS | 1 |
| Jesse, CR; Nogueira, CW; Savegnago, L | 1 |
| Coe, IR; Naydenova, Z; Rose, JB | 1 |
| Catarzi, D; Ciampi, O; Colotta, V; Filacchioni, G; Lenzi, O; Martini, C; Morizzo, E; Moro, S; Pedata, F; Pugliese, AM; Traini, C; Trincavelli, L; Varano, F | 1 |
| Grzelak, ME; Hodgson, RA; Hunter, JC; Parker, EM; Pond, AJ; Varty, GB | 1 |
| Broadley, KJ; Smith, N | 1 |
| Arcella, A; Cantore, G; Di Gennaro, G; Esposito, V; Eusebi, F; Fredholm, BB; Fucile, S; Limatola, C; Manfredi, M; Martinello, K; Mascia, A; Miledi, R; Piccari, V; Quarato, PP; Roseti, C; Simonato, M | 1 |
| Ahlawat, R; Chavez-Valdez, R; Cristofalo, EA; Gauda, EB; Nathan, A; Wills-Karp, M | 1 |
| Antunes, C; Böhmer, AE; Elisabetsky, E; Lara, DR; Porciúncula, LO; Schallenberger, C; Schmidt, AP; Souza, DO | 1 |
| Baghdoyan, HA; Lydic, R; Van Dort, CJ | 1 |
| Chen, CY; Chiu, TH; Hsu, CW; Wang, CS | 1 |
| Fernandes, D; Pamplona, FA; Pandolfo, P; Pires, VA; Prediger, RD; Takahashi, RN | 1 |
| Church, JE; Coupar, IM; Pouton, CW; Rose'Meyer, RB; Urmaliya, VB; White, PJ | 1 |
| Bertram, EH; Hargus, NJ; Patel, MK | 1 |
| Krahn, T; Ledent, C; Mustafa, SJ; Ponnoth, DS; Roush, K; Sanjani, MS | 1 |
| Agostinho, PM; Cognato, GP; Cunha, RA; Hockemeyer, J; Müller, CE; Souza, DO | 1 |
| Brennum, LT; Chrobak, JJ; Collins, LE; Galtieri, DJ; Hinman, JR; Hockemeyer, J; Müller, CE; Sager, TN; Salamone, JD | 1 |
| Eyanagi, R; Imoto, M; Kuroki, H; Nishimura, S; Shimeno, H; Soeda, S; Toda, A; Uchiyama, H; Watanabe, S | 1 |
| Chiu, TH; Hsu, CW; Wang, CS | 1 |
| Chen, SR; Li, DP; Pan, HL | 1 |
| Pao, AC; Rajagopal, M | 1 |
| Ferguson, AL; Stone, TW | 1 |
| Ledent, C; Pouton, CW; Short, JL; Urmaliya, VB; White, PJ | 1 |
| Agostinho, PM; Canas, PM; Costenla, AR; Cunha, RA; de Mendonça, A; Diógenes, MJ; Maroco, J; Nogueira, C; Ribeiro, JA; Rodrigues, RJ | 1 |
| Li, W; Zhang, JJ | 1 |
| Blanco, C; Colettis, N; Hartley, RC; Harvey, AL; Jamieson, AG; Jerusalinsky, D; Kornisiuk, E; Snitcofsky, M; Stone, TW; Young, LC | 1 |
| Azevedo, MS; Cechinel-Filho, V; Ferreira, VM; Lucena, GM; Matheus, FC; Prediger, RD; Tessele, PB | 1 |
| Martins, DF; Mazzardo-Martins, L; Piovezan, AP; Santos, AR; Soldi, F; Stramosk, J | 1 |
| Albasanz, JL; Barrachina, M; Blanch, M; Díaz-Sánchez, S; Ferrer, I; Martín, M; Monje, A; Pereira-Veiga, T; Planchat, LM; Villar-Menéndez, I | 1 |
| Dubroqua, S; Singer, P; Yee, BK | 1 |
| Ballanyi, K; Ciechanski, P; Mosca, EV; Roy, A; Scheibli, EC; Wilson, RJ | 1 |
| Andriolo, V; Castorina, A; Giunta, S | 1 |
| Almeida, AS; Botton, PH; Chenet, GC; Cunha, RA; Loss, CM; Marques, DM; Mioranzza, S; Nunes, F; Pagnussat, N; Porciúncula, LO | 1 |
| Guo, D; Hankemeier, T; Hölscher, A; Holzheimer, M; IJzerman, AP; Louvel, J; Massink, A; Spijksma, G | 1 |
| Jia, SB; Shi, JG; Zhang, JJ; Zhang, Y | 1 |
| Alves, PM; Alves, RM; Conde, SV; Queiroga, CS; Vieira, HL | 1 |
| Bai, X; He, J; Li, T; Qiao, H; Xu, J; Ye, X; Zhang, J; Zhang, W | 1 |
| Ari, C; Brunner, B; D'Agostino, DP; Kovács, Z | 1 |
1 review(s) available for triazoles and 1,3-dipropyl-8-cyclopentylxanthine
| Article | Year |
|---|---|
Progress in the pursuit of therapeutic adenosine receptor antagonists.
Topics: Adenosine A1 Receptor Antagonists; Adenosine A2 Receptor Antagonists; Adenosine A3 Receptor Antagonists; Amino Acid Sequence; Animals; Flavonoids; Heterocyclic Compounds; Humans; Purinergic P1 Receptor Antagonists; Quantitative Structure-Activity Relationship; Quinazolines; Receptor, Adenosine A2B; Triazoles; Xanthines | 2006 |
153 other study(ies) available for triazoles and 1,3-dipropyl-8-cyclopentylxanthine
| Article | Year |
|---|---|
Excitatory transmitter amino acid release from the ischemic rat cerebral cortex: effects of adenosine receptor agonists and antagonists.
Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Aspartic Acid; Brain Ischemia; Cerebral Cortex; Glutamates; Glutamic Acid; Male; Neurotransmitter Agents; Purinergic Antagonists; Quinazolines; Rats; Rats, Inbred Strains; Receptors, Purinergic; Triazoles; Xanthines | 1992 |
Evidence that the increase in striatal c-fos following acute high-dose caffeine is not due to direct interaction with striatal adenosine receptors.
Topics: Adenosine; Animals; Caffeine; Corpus Striatum; Dose-Response Relationship, Drug; Genes, fos; Purinergic Antagonists; Quinazolines; Rats; RNA, Messenger; Triazoles; Xanthines | 1992 |
Subtypes of adenosine receptors in the brainstem mediate opposite blood pressure responses.
Topics: Adenosine; Animals; Antihypertensive Agents; Blood Pressure; Brain Stem; Dose-Response Relationship, Drug; Male; Phenethylamines; Quinazolines; Rats; Rats, Inbred Strains; Receptors, Purinergic; Triazoles; Xanthines | 1991 |
Comparison of the behavioural effects of an adenosine A1/A2-receptor antagonist, CGS 15943A, and an A1-selective antagonist, DPCPX.
Topics: Adenosine; Animals; Behavior, Animal; Dose-Response Relationship, Drug; Exploratory Behavior; Male; Mice; Motor Activity; Purinergic Antagonists; Quinazolines; Triazoles; Xanthines | 1991 |
Differential antagonism by 1,3-dipropylxanthine-8-cyclopentylxanthine and 9-chloro-2-(2-furanyl)-5,6-dihydro-1,2,4-triazolo(1,5-c)quinazolin-5-im ine of the effects of adenosine derivatives in the presence of isoprenaline on contractile response and cycli
Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Cyclic AMP; Drug Interactions; Electric Stimulation; Female; Guinea Pigs; Heart; Isoproterenol; Male; Myocardial Contraction; Quinazolines; Receptors, Purinergic; Triazoles; Vasodilator Agents; Xanthines | 1990 |
Effects of the adenosine A1-receptor antagonist on defecation, small intestinal propulsion and gastric emptying in rats.
Topics: Adamantane; Animals; Bisacodyl; Defecation; Gastric Emptying; Gastrointestinal Motility; Imidazoles; Intestine, Small; Male; Purinergic P1 Receptor Antagonists; Pyrazines; Quinazolines; Rats; Rats, Sprague-Dawley; Triazoles; Xanthines | 1995 |
The A1 agonist CCPA reduced bisoxonol-monitored membrane potential depolarization elicited by high K+ in cerebrocortical nerve endings.
Topics: Adenosine; Animals; Cerebral Cortex; Fluorescent Dyes; Male; Membrane Potentials; Nerve Endings; Phenethylamines; Potassium; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Quinazolines; Rats; Rats, Wistar; Synaptosomes; Thiobarbiturates; Triazoles; Veratridine; Xanthines | 1995 |
Further investigations into adenosine A1 receptor-mediated contraction in rat colonic muscularis mucosae and its augmentation by certain alkylxanthine antagonists.
Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Colon; Cyclooxygenase Inhibitors; In Vitro Techniques; Indomethacin; Intestinal Mucosa; Muscle Contraction; Muscle, Smooth; Phosphodiesterase Inhibitors; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Quinazolines; Rats; Theophylline; Triazoles; Vasodilator Agents; Xanthines | 1995 |
Adenosine and PAF dependent mechanisms lead to myocardial reperfusion injury by neutrophils after brief ischaemia.
Topics: Adenosine; Animals; Azepines; Guinea Pigs; Heart; Male; Myocardial Ischemia; Myocardial Reperfusion Injury; Neutrophil Activation; Neutrophils; Perfusion; Platelet Activating Factor; Receptors, Purinergic P1; Theobromine; Triazoles; Xanthines | 1995 |
Pharmacological characterization of A2-adenosine receptors in guinea-pig ventricular cardiomyocytes.
Topics: Adenosine; Adenylate Cyclase Toxin; Adenylyl Cyclases; Animals; Cells, Cultured; Cyclic AMP; Drug Interactions; Female; Guinea Pigs; Heart Ventricles; Isoproterenol; Male; Myocardial Contraction; Myocardium; Papillary Muscles; Pertussis Toxin; Phenethylamines; Quinazolines; Receptors, Adrenergic, beta; Receptors, Purinergic P1; Signal Transduction; Triazoles; Virulence Factors, Bordetella; Xanthines | 1994 |
Blockade of A2a adenosine receptors positively modulates turning behaviour and c-Fos expression induced by D1 agonists in dopamine-denervated rats.
Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Animals; Denervation; Male; Motor Activity; Nerve Tissue Proteins; Oxidopamine; Proto-Oncogene Proteins c-fos; Purinergic P1 Receptor Antagonists; Pyrimidines; Quinazolines; Rats; Rats, Sprague-Dawley; Receptors, Dopamine D1; Rotation; Triazoles; Xanthines | 1996 |
Augmented release of serotonin by adenosine A2a receptor activation and desensitization by CGS 21680 in the rat nucleus tractus solitarius.
Topics: Adenosine; Animals; In Vitro Techniques; Kinetics; Male; Phenethylamines; Purinergic P1 Receptor Agonists; Quinazolines; Rats; Rats, Sprague-Dawley; Receptors, Purinergic P1; Serotonin; Solitary Nucleus; Triazoles; Xanthines | 1996 |
Repeated treatment with adenosine A1 receptor agonist and antagonist modifies the anticonvulsant properties of CPPene.
Topics: Acoustic Stimulation; Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Anticonvulsants; Dose-Response Relationship, Drug; Excitatory Amino Acid Antagonists; Injections, Intraventricular; Male; Mice; Mice, Inbred DBA; Piperazines; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Pyrimidines; Triazoles; Xanthines | 1996 |
Desensitisation of the adenosine A1 receptor by the A2A receptor in the rat striatum.
Topics: Adenosine; Animals; Antihypertensive Agents; Corpus Striatum; Enzyme Inhibitors; Isoquinolines; Phenethylamines; Presynaptic Terminals; Protein Kinase C; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Rats; Rats, Wistar; Receptor, Adenosine A2A; Receptors, Purinergic P1; Sensitivity and Specificity; Sulfonamides; Synaptosomes; Triazines; Triazoles; Tritium; Xanthines | 1997 |
Neonatal cerebral hypoxia-ischemia: the effect of adenosine receptor antagonists.
Topics: Animals; Animals, Newborn; Blood Gas Analysis; Blood Glucose; Body Temperature; Body Weight; Brain; Brain Ischemia; Cerebrovascular Circulation; Female; Hypoxia, Brain; Male; Purinergic P1 Receptor Antagonists; Pyrimidines; Rats; Rats, Wistar; Receptor, Adenosine A2A; RNA, Messenger; Theophylline; Triazoles; Xanthines | 1997 |
Adenosine A1 receptor-mediated activation of AMP-activated protein kinase in bovine bronchial rings.
Topics: Adenosine-5'-(N-ethylcarboxamide); Aminoimidazole Carboxamide; AMP-Activated Protein Kinases; Animals; Bronchi; Cattle; Enzyme Activation; In Vitro Techniques; Multienzyme Complexes; Phenylisopropyladenosine; Protein Kinases; Protein Serine-Threonine Kinases; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Receptors, Purinergic P1; Ribonucleotides; Triazines; Triazoles; Xanthines | 1997 |
The A2A adenosine receptor mediates coronary vasodilation.
Topics: Adenosine; Animals; Coronary Vessels; Female; Guinea Pigs; Male; Perfusion; Phenethylamines; Piperazines; Pyrimidines; Receptors, Purinergic P1; Triazoles; Tubercidin; Vasodilation; Xanthines | 1998 |
Protection against kainate-induced excitotoxicity by adenosine A2A receptor agonists and antagonists.
Topics: Adenosine; Animals; Excitatory Amino Acid Agonists; Hippocampus; Kainic Acid; Male; Neurons; Neuroprotective Agents; Phenethylamines; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Rats; Rats, Wistar; Triazines; Triazoles; Xanthines | 1998 |
Motor stimulant effects of caffeine in 6-hydroxydopamine-lesioned rats are dependent on previous stimulation of dopamine receptors: a different role of D1 and D2 receptors.
Topics: Animals; Apomorphine; Caffeine; Central Nervous System Stimulants; Dopamine Agonists; Male; Motor Activity; Oxidopamine; Purinergic P1 Receptor Antagonists; Pyrimidines; Rats; Rats, Sprague-Dawley; Receptors, Dopamine D1; Receptors, Dopamine D2; Rotation; Stimulation, Chemical; Triazoles; Xanthines | 1998 |
Adenosine receptor subtypes and vasodilatation in rat skeletal muscle during systemic hypoxia: a role for A1 receptors.
Topics: Adenosine; Animals; Antihypertensive Agents; Blood Gas Analysis; Hydrogen-Ion Concentration; Hypoxia; Male; Muscle, Skeletal; Phenethylamines; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Rats; Rats, Wistar; Receptors, Purinergic P1; Regional Blood Flow; Respiration; Triazines; Triazoles; Vasodilation; Vasodilator Agents; Xanthines | 1999 |
Adenosine A2a receptors increase arterial endothelial cell nitric oxide.
Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Carotid Arteries; Cells, Cultured; Endothelium, Vascular; Humans; Iliac Artery; Nitric Oxide; Phenethylamines; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Quinazolines; Receptor, Adenosine A2A; Receptors, Purinergic P1; Swine; Triazines; Triazoles; Xanthines | 1998 |
Comparison of CGS 15943, ZM 241385 and SCH 58261 as antagonists at human adenosine receptors.
Topics: Animals; Cell Line; CHO Cells; Cricetinae; Cyclic AMP; Humans; Purinergic P1 Receptor Antagonists; Pyrimidines; Quinazolines; Rats; Transfection; Triazines; Triazoles; Xanthines | 1999 |
Adenosine and dopamine receptor antagonist binding in the rat ventral and dorsal striatum: lack of changes after a neonatal bilateral lesion of the ventral hippocampus.
Topics: Animals; Animals, Newborn; Antipsychotic Agents; Benzazepines; Corpus Striatum; Disease Models, Animal; Dopamine Antagonists; Female; Hippocampus; Male; Pregnancy; Purinergic P1 Receptor Antagonists; Pyrimidines; Raclopride; Radioligand Assay; Rats; Rats, Sprague-Dawley; Receptors, Purinergic P1; Salicylamides; Schizophrenia; Triazoles; Xanthines | 1999 |
Caffeine, acting on adenosine A(1) receptors, prevents the extinction of cocaine-seeking behavior in mice.
Topics: Animals; Behavior, Animal; Caffeine; Cocaine; Extinction, Psychological; Male; Mice; Mice, Inbred DBA; Purinergic P1 Receptor Antagonists; Pyrimidines; Quinazolines; Reward; Substance Abuse, Intravenous; Theophylline; Triazoles; Xanthines | 1999 |
Adenosine and memory storage: effect of A(1) and A(2) receptor antagonists.
Topics: Adenosine; Animals; Avoidance Learning; Caffeine; Central Nervous System Stimulants; Male; Memory; Mice; Purinergic P1 Receptor Antagonists; Pyrimidines; Triazoles; Xanthines | 1999 |
Effect of A2A adenosine receptor stimulation and antagonism on synaptic depression induced by in vitro ischaemia in rat hippocampal slices.
Topics: Adenosine; Animals; Excitatory Postsynaptic Potentials; Hippocampus; Hypoxia-Ischemia, Brain; In Vitro Techniques; Male; Phenethylamines; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Pyrimidines; Rats; Rats, Wistar; Receptor, Adenosine A2A; Synapses; Synaptic Transmission; Triazines; Triazoles; Xanthines | 1999 |
Adenosine inhibits a non-inactivating K+ current in bovine adrenal cortical cells by activation of multiple P1 receptors.
Topics: Adenosine; Adenosine Triphosphate; Adenosine-5'-(N-ethylcarboxamide); Animals; Cattle; GTP-Binding Proteins; In Vitro Techniques; Male; Membrane Potentials; Patch-Clamp Techniques; Potassium; Potassium Channel Blockers; Potassium Channels; Receptors, Purinergic P1; Signal Transduction; Triazines; Triazoles; Xanthines; Zona Fasciculata | 1999 |
Sensitization of visceral afferents to bradykinin in rat jejunum in vitro.
Topics: Adenosine; Animals; Bradykinin; Bucladesine; Cyclooxygenase Inhibitors; Dinoprostone; Histamine; Histamine Antagonists; Histamine H2 Antagonists; In Vitro Techniques; Jejunum; Male; Membrane Potentials; Naproxen; Neurons, Afferent; Piperidines; Ranitidine; Rats; Rats, Inbred Strains; Serotonin; Stimulation, Chemical; Triazines; Triazoles; Xanthines | 1999 |
Increase in the vasorelaxant potency of K(ATP) channel opening drugs by adenosine A(1) and A(2) receptors in the pig coronary artery.
Topics: Adenosine; Animals; ATP-Binding Cassette Transporters; Coronary Vessels; Cromakalim; Dose-Response Relationship, Drug; Drug Interactions; In Vitro Techniques; KATP Channels; Nicorandil; Phenethylamines; Pinacidil; Potassium Channels; Potassium Channels, Inwardly Rectifying; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Swine; Triazines; Triazoles; Vasodilator Agents; Xanthines | 1999 |
Afferent arteriolar adenosine A2a receptors are coupled to KATP in in vitro perfused hydronephrotic rat kidney.
Topics: 4-(3-Butoxy-4-methoxybenzyl)-2-imidazolidinone; Adenosine; Adenosine Triphosphate; Adenosine-5'-(N-ethylcarboxamide); Animals; Arterioles; Blood Pressure; Enzyme Inhibitors; Hydronephrosis; Kidney; Perfusion; Potassium Channels; Potassium Chloride; Rats; Receptor, Adenosine A2A; Receptors, Purinergic P1; Renal Artery; Renal Circulation; Triazines; Triazoles; Vasoconstriction; Vasodilation; Vasodilator Agents; Xanthines | 1999 |
Cross talk between A(1) and A(2A) adenosine receptors in the hippocampus and cortex of young adult and old rats.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Adenosine; Aging; Animals; Binding, Competitive; Cerebral Cortex; Electrophysiology; Hippocampus; In Vitro Techniques; Male; Phenethylamines; Protein Kinase C; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Rats; Rats, Wistar; Receptor Cross-Talk; Receptor, Adenosine A2A; Receptors, Purinergic P1; Synaptic Membranes; Triazines; Triazoles; Xanthines | 1999 |
The anxiogenic-like effect of caffeine in two experimental procedures measuring anxiety in the mouse is not shared by selective A(2A) adenosine receptor antagonists.
Topics: Adenosine; Administration, Oral; Animals; Anxiety; Behavior, Animal; Caffeine; Darkness; Drug Administration Schedule; Injections, Intraperitoneal; Light; Male; Maze Learning; Mice; Mice, Knockout; Neuroprotective Agents; Phenethylamines; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Pyrimidines; Reaction Time; Receptor, Adenosine A2A; Triazines; Triazoles; Xanthines | 2000 |
The stimulant effects of caffeine on locomotor behaviour in mice are mediated through its blockade of adenosine A(2A) receptors.
Topics: Analysis of Variance; Animals; Behavior, Animal; Caffeine; Central Nervous System Stimulants; Dose-Response Relationship, Drug; Habituation, Psychophysiologic; Male; Mice; Mice, Knockout; Motor Activity; Purinergic P1 Receptor Antagonists; Pyrimidines; Receptor, Adenosine A2A; Receptors, Purinergic P1; Triazoles; Xanthines | 2000 |
Tonic adenosine neuromodulation is preserved in motor nerve endings of aged rats.
Topics: Acetylcholine; Adenosine; Aging; Animals; Electric Stimulation; Male; Motor Neurons; Nerve Endings; Neurotransmitter Agents; Phrenic Nerve; Purinergic P1 Receptor Antagonists; Rats; Rats, Wistar; Triazines; Triazoles; Xanthines | 2000 |
Adenosine acts as a chemoprotective agent by stimulating G-CSF production: a role for A1 and A3 adenosine receptors.
Topics: Adenosine; Animals; Bone Marrow Cells; Cell Cycle; Cell Division; Cells, Cultured; Cyclophosphamide; Granulocyte Colony-Stimulating Factor; Humans; Leukocytes, Mononuclear; Male; Mice; Mice, Inbred C57BL; Mice, Inbred ICR; Purinergic P1 Receptor Antagonists; Quinazolines; Receptor, Adenosine A3; Receptors, Purinergic P1; Theobromine; Triazoles; Xanthines | 2000 |
Renal adenosine A3 receptors in the rat: assessment of functional role.
Topics: Animals; Dihydropyridines; Diuresis; Glomerular Filtration Rate; Kidney; Male; Natriuresis; Potassium; Purinergic P1 Receptor Antagonists; Quinazolines; Rats; Rats, Inbred WKY; Receptor, Adenosine A3; Receptors, Purinergic P1; Sodium; Triazoles; Urodynamics; Xanthines | 2000 |
A novel adenosine analog, AMP579, inhibits neutrophil activation, adherence and neutrophil-mediated injury to coronary vascular endothelium.
Topics: Animals; Cell Adhesion; Cell Degranulation; Coronary Vessels; Dogs; Dose-Response Relationship, Drug; Endothelium, Vascular; Female; Imidazoles; In Vitro Techniques; Male; Neutrophil Activation; Neutrophils; Pyridines; Quinazolines; Superoxides; Triazines; Triazoles; Vasodilation; Xanthines | 2000 |
Adenosine A2A receptors regulate the extracellular accumulation of excitatory amino acids upon metabolic dysfunction in chick cultured retinal cells.
Topics: Adenosine; Analysis of Variance; Animals; Aspartic Acid; Bicuculline; Cells, Cultured; Chick Embryo; Chromatography, High Pressure Liquid; Excitatory Amino Acids; Extracellular Space; GABA-A Receptor Antagonists; GABA-B Receptor Antagonists; gamma-Aminobutyric Acid; Glutamic Acid; Glycolysis; Humans; Ischemia; Organophosphorus Compounds; Purinergic P1 Receptor Antagonists; Pyrimidines; Receptor, Adenosine A2A; Receptors, Purinergic P1; Retina; Triazines; Triazoles; Xanthines | 2000 |
Extracellular ATP reduces optically monitored electrical signals in hippocampal slices through metabolism to adenosine.
Topics: Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Animals; Dose-Response Relationship, Drug; Electric Stimulation; Electrophysiology; Hippocampus; Organ Culture Techniques; Rats; Rats, Wistar; Signal Transduction; Triazines; Triazoles; Uridine Diphosphate; Xanthines | 2000 |
GTP differentially affects antagonist radioligand binding to adenosine A(1) and A(2A) receptors in human brain.
Topics: Animals; Autoradiography; Brain Chemistry; Cell Membrane; CHO Cells; Cricetinae; Guanosine Triphosphate; Humans; Purinergic P1 Receptor Antagonists; Pyrimidines; Radioligand Assay; Receptor, Adenosine A2A; Receptors, Purinergic P1; Thermodynamics; Triazoles; Xanthines | 2000 |
Diadenosine polyphosphates facilitate the evoked release of acetylcholine from rat hippocampal nerve terminals.
Topics: Acetylcholine; Animals; Dinucleoside Phosphates; Hippocampus; Male; Presynaptic Terminals; Pyridoxal Phosphate; Rats; Rats, Wistar; Receptors, Purinergic P1; Suramin; Synaptosomes; Triazines; Triazoles; Tritium; Xanthines | 2000 |
Adenosine A(1) and A(3) receptors mediate inhibition of synaptic transmission in rat cortical neurons.
Topics: Adenosine; Animals; Cerebral Cortex; Drug Interactions; Electric Stimulation; Female; In Vitro Techniques; Male; Neurons; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Quinazolines; Rats; Rats, Wistar; Receptor, Adenosine A3; Receptors, Purinergic P1; Synaptic Transmission; Triazoles; Xanthines | 2001 |
Adenosine A(2A) receptors mediate cardiovascular responses to hypoxia in fetal sheep.
Topics: Adenosine; Animals; Blood Gas Analysis; Blood Pressure; Female; Fetal Hypoxia; Heart Rate; Hydrogen-Ion Concentration; Phenethylamines; Pregnancy; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Receptor, Adenosine A2A; Receptors, Purinergic P1; Sheep; Triazines; Triazoles; Xanthines | 2001 |
Neuroprotection by caffeine and A(2A) adenosine receptor inactivation in a model of Parkinson's disease.
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; 3,4-Dihydroxyphenylacetic Acid; Animals; Caffeine; Catechols; Corpus Striatum; Disease Models, Animal; Dopamine; Dose-Response Relationship, Drug; Immunity, Innate; Injections, Intraperitoneal; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Neuroprotective Agents; Parkinsonian Disorders; Purinergic P1 Receptor Antagonists; Purines; Pyrimidines; Receptor, Adenosine A2A; Receptors, Purinergic P1; Theobromine; Triazoles; Xanthines | 2001 |
Adenosine A(1) and A(2A) receptors modulate sleep state and breathing in fetal sheep.
Topics: Adenosine; Animals; Fetus; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Receptors, Purinergic P1; Respiratory Physiological Phenomena; Sheep; Sleep Stages; Triazines; Triazoles; Xanthines | 2001 |
Adenosine-mediated inhibition of striatal GABAergic synaptic transmission during in vitro ischaemia.
Topics: Adenosine; Adenosine Triphosphate; Animals; Brain Ischemia; Corpus Striatum; gamma-Aminobutyric Acid; Male; Membrane Potentials; Neural Inhibition; Organ Culture Techniques; Patch-Clamp Techniques; Potassium Channels; Purinergic P1 Receptor Antagonists; Rats; Rats, Wistar; Synaptic Transmission; Triazines; Triazoles; Xanthines | 2001 |
Pharmacological and biochemical characterization of A3 adenosine receptors in Jurkat T cells.
Topics: Animals; Binding, Competitive; Calcium; CHO Cells; Cricetinae; Cyclic AMP; Dose-Response Relationship, Drug; Guanosine Triphosphate; Humans; Jurkat Cells; Kinetics; Phenylurea Compounds; Purinergic P1 Receptor Agonists; Pyrimidines; Receptor, Adenosine A2A; Receptor, Adenosine A3; Receptors, Purinergic P1; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; T-Lymphocytes; Thermodynamics; Time Factors; Triazoles; Tritium; Xanthines | 2001 |
Effects of adenosine receptor agonists and antagonists in a genetic animal model of primary paroxysmal dystonia.
Topics: Adenosine; Animals; Caffeine; Cricetinae; Disease Models, Animal; Dose-Response Relationship, Drug; Dystonia; Female; Male; Mesocricetus; Muscle Contraction; Mutation; Phenethylamines; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Quinazolines; Theobromine; Theophylline; Triazines; Triazoles; Xanthines | 2001 |
Adenosine-mediated hypotension in in vivo guinea-pig: receptors involved and role of NO.
Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Blood Pressure; Diphenhydramine; Dose-Response Relationship, Drug; Enzyme Inhibitors; Guinea Pigs; Heart Rate; Hypotension; Male; Methylene Blue; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Phenethylamines; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Receptors, Purinergic P1; Theophylline; Triazines; Triazoles; Vasodilator Agents; Xanthines | 2001 |
AMP-activated protein kinase is highly expressed in neurons in the developing rat brain and promotes neuronal survival following glucose deprivation.
Topics: Aminoimidazole Carboxamide; AMP-Activated Protein Kinases; Animals; Apoptosis; Brain; Cell Survival; Cells, Cultured; Glucose; Hypoglycemic Agents; Immunohistochemistry; Male; Multienzyme Complexes; Neurons; Neuroprotective Agents; Oligonucleotides, Antisense; Protein Serine-Threonine Kinases; Protein Subunits; Rats; Rats, Sprague-Dawley; Ribonucleotides; Triazines; Triazoles; Xanthines | 2001 |
Effect of adenosine receptor blockade on pial arteriolar dilation during sciatic nerve stimulation.
Topics: Adenine; Administration, Topical; Animals; Electric Stimulation; Enzyme Inhibitors; Evoked Potentials, Somatosensory; Injections, Intraperitoneal; Male; Pia Mater; Purinergic P1 Receptor Antagonists; Rats; Rats, Sprague-Dawley; Sciatic Nerve; Theophylline; Triazines; Triazoles; Vasodilation; Vasodilator Agents; Xanthines | 2001 |
Oxygen delivery and oxygen consumption in rat hindlimb during systemic hypoxia: role of adenosine.
Topics: Adenosine; Animals; Hemodynamics; Hindlimb; Hypoxia; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Donors; Nitric Oxide Synthase; Nitroprusside; Oxygen Consumption; Rats; Rats, Wistar; Receptor, Adenosine A2A; Receptors, Purinergic P1; Triazines; Triazoles; Vital Capacity; Xanthines | 2001 |
Regulation of K(+) current in human airway epithelial cells by exogenous and autocrine adenosine.
Topics: 4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid; Adenosine; Affinity Labels; Amiloride; Autocrine Communication; Cell Line; Cell Polarity; Clotrimazole; Diuretics; Epithelial Cells; Equilibrative Nucleoside Transporter 1; Equilibrative-Nucleoside Transporter 2; Growth Inhibitors; Humans; Membrane Transport Proteins; Patch-Clamp Techniques; Potassium; Potassium Channels; Quinazolines; Receptors, Purinergic P1; Respiratory Mucosa; Theobromine; Thioinosine; Triazoles; Uridine; Xanthines | 2001 |
Pharmacological and biochemical characterization of adenosine receptors in the human malignant melanoma A375 cell line.
Topics: Adenosine Deaminase; Binding, Competitive; Calcium; Cell Membrane; Cyclic AMP; Humans; Melanoma, Experimental; Phenylurea Compounds; Purinergic P1 Receptor Antagonists; Pyrimidines; Radioligand Assay; Receptors, Purinergic P1; Reverse Transcriptase Polymerase Chain Reaction; Skin Neoplasms; Triazoles; Tritium; Tumor Cells, Cultured; Xanthines | 2001 |
Adenosine inhibits excitatory transmission to substantia gelatinosa neurons of the adult rat spinal cord through the activation of presynaptic A(1) adenosine receptor.
Topics: Adenosine; Age Factors; Analgesics; Animals; Antihypertensive Agents; Excitatory Postsynaptic Potentials; In Vitro Techniques; Male; Neural Inhibition; Neurons; Patch-Clamp Techniques; Phenethylamines; Rats; Rats, Sprague-Dawley; Receptors, Purinergic P1; Substantia Gelatinosa; Triazines; Triazoles; Xanthines | 2001 |
Effects of A(3) adenosine receptor activation and gene knock-out in ischemic-reperfused mouse heart.
Topics: Adenosine; Amino Acids; Animals; Creatine; Heart Rate; Hydrogen-Ion Concentration; Magnetic Resonance Spectroscopy; Mice; Mice, Inbred C57BL; Mice, Knockout; Myocardial Contraction; Myocardial Reperfusion Injury; Myocardium; Perfusion; Phenethylamines; Pipecolic Acids; Purinergic P1 Receptor Antagonists; Quinazolines; Receptor, Adenosine A3; Receptors, Purinergic P1; Triazoles; Xanthines | 2002 |
Diverse inhibitors of intracellular signalling act as adenosine receptor antagonists.
Topics: Adenine; Adenylyl Cyclase Inhibitors; Alkaloids; Animals; Benzophenanthridines; CHO Cells; Cricetinae; Cyclic AMP Response Element-Binding Protein; Cytoplasm; Dose-Response Relationship, Drug; Enzyme Inhibitors; Genistein; Male; Mice; Mitogen-Activated Protein Kinases; Phenanthridines; Phosphorylation; Protein Kinase C; Purinergic P1 Receptor Antagonists; Pyrimidines; Rats; Rats, Sprague-Dawley; Signal Transduction; Triazoles; Xanthines | 2002 |
Adenosine A(2A) receptors mediate hypoxic inhibition of fetal breathing in sheep.
Topics: Animals; Carbon Dioxide; Electroencephalography; Electrooculography; Eye Movements; Female; Fetal Blood; Fetal Hypoxia; Fetal Movement; Fetus; Hydrogen-Ion Concentration; Oxygen; Pregnancy; Purinergic P1 Receptor Antagonists; Receptor, Adenosine A2A; Receptors, Purinergic P1; Respiration; Sheep; Triazines; Triazoles; Xanthines | 2002 |
Effects of adenosine A1 and A2A receptor activation on the evoked release of glutamate from rat cerebrocortical synaptosomes.
Topics: Adenosine; Analysis of Variance; Animals; Cerebral Cortex; Chromatography, High Pressure Liquid; Glutamic Acid; In Vitro Techniques; Male; Phenethylamines; Purinergic P1 Receptor Agonists; Pyrimidines; Rats; Rats, Sprague-Dawley; Receptor, Adenosine A2A; Synaptosomes; Triazoles; Xanthines | 2002 |
Adenosine A(2A) receptor facilitation of hippocampal synaptic transmission is dependent on tonic A(1) receptor inhibition.
Topics: Adenosine; Animals; Binding, Competitive; CHO Cells; Cricetinae; Cyclic AMP; Enzyme Inhibitors; Excitatory Postsynaptic Potentials; GABA Antagonists; gamma-Aminobutyric Acid; Glutamic Acid; Hippocampus; Humans; In Vitro Techniques; Ligands; Male; Phenethylamines; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Rats; Rats, Wistar; Receptor, Adenosine A2A; Receptors, Purinergic P1; Signal Transduction; Synaptic Transmission; Transfection; Triazines; Triazoles; Xanthines | 2002 |
Synergistic up-regulation of vascular endothelial growth factor expression in murine macrophages by adenosine A(2A) receptor agonists and endotoxin.
Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Blotting, Western; Cells, Cultured; Drosophila Proteins; Endothelial Growth Factors; Female; Interferon-gamma; Lipopolysaccharides; Lymphokines; Macrophages, Peritoneal; Male; Membrane Glycoproteins; Mice; Mice, Inbred C3H; Mice, Inbred C57BL; Mice, Knockout; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Phenethylamines; Protein Kinase Inhibitors; Purinergic P1 Receptor Agonists; Receptor, Adenosine A2A; Receptors, Cell Surface; Receptors, Purinergic P1; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Signal Transduction; Theobromine; Toll-Like Receptor 4; Toll-Like Receptors; Triazines; Triazoles; Up-Regulation; Vascular Endothelial Growth Factor A; Vascular Endothelial Growth Factors; Xanthines | 2002 |
Selective allosteric enhancement of agonist binding and function at human A3 adenosine receptors by a series of imidazoquinoline derivatives.
Topics: Adenosine; Allosteric Regulation; Animals; Binding, Competitive; CHO Cells; Cricetinae; Dose-Response Relationship, Drug; Imidazoles; Iodine Radioisotopes; Phenethylamines; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Purines; Quinolines; Radioligand Assay; Rats; Receptor, Adenosine A2A; Receptor, Adenosine A3; Receptors, Purinergic P1; Triazines; Triazoles; Tritium; Xanthines | 2002 |
Differential effects of caffeine on dopamine and acetylcholine transmission in brain areas of drug-naive and caffeine-pretreated rats.
Topics: Acetylcholine; Animals; Behavior, Animal; Caffeine; Central Nervous System Stimulants; Dopamine; Dose-Response Relationship, Drug; Drug Administration Schedule; Extracellular Space; Injections, Intraperitoneal; Male; Microdialysis; Neuroprotective Agents; Nucleus Accumbens; Prefrontal Cortex; Presynaptic Terminals; Pyrimidines; Rats; Rats, Sprague-Dawley; Synaptic Transmission; Triazoles; Xanthines | 2002 |
Autocrine activation of adenosine A1 receptors blocks D1A but not D1B dopamine receptor desensitization.
Topics: Adenosine; Animals; Autocrine Communication; Cell Line; COS Cells; Cyclic AMP; Dopamine Agonists; Fibroblasts; Mice; Phosphodiesterase Inhibitors; Quinazolines; Receptors, Dopamine D1; Receptors, Dopamine D5; Receptors, Purinergic P1; Time Factors; Transfection; Triazoles; Xanthines | 2002 |
Broad spectrum anticonvulsant activity of BW534U87: possible role of an adenosine-dependent mechanism.
Topics: Adenine; Adenosine; Adenosine Deaminase; Adenosine Deaminase Inhibitors; Amygdala; Animals; Anticonvulsants; Convulsants; Dose-Response Relationship, Drug; Electroshock; Enzyme Inhibitors; Female; Kindling, Neurologic; Male; Mice; Pentylenetetrazole; Purinergic P1 Receptor Antagonists; Rats; Rats, Wistar; Seizures; Triazoles; Xanthines | 2002 |
Transducing system operated by adenosine A(2A) receptors to facilitate acetylcholine release in the rat hippocampus.
Topics: Acetylcholine; Adenylyl Cyclases; Animals; Blotting, Western; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Dose-Response Relationship, Drug; Enzyme Activation; Hippocampus; In Vitro Techniques; Male; Nerve Endings; Protein Kinase C; Purinergic P1 Receptor Antagonists; Pyrimidines; Rats; Rats, Wistar; Receptor, Adenosine A2A; Receptors, Purinergic P1; Signal Transduction; Synaptosomes; Triazines; Triazoles; Xanthines | 2002 |
Regional differences in the adenosine A(2) receptor-mediated modulation of contractions in rat vas deferens.
Topics: Adenosine; Adenosine Triphosphate; Adenosine-5'-(N-ethylcarboxamide); Animals; Epididymis; Immunohistochemistry; In Vitro Techniques; Male; Muscle Contraction; Norepinephrine; Phenethylamines; Prostate; Rats; Rats, Wistar; Receptor, Adenosine A2A; Receptors, Purinergic P1; Theobromine; Triazines; Triazoles; Vas Deferens; Xanthines | 2003 |
Adenosine promotes neuronal recovery from reactive oxygen species induced lesion in rat hippocampal slices.
Topics: Adenosine; Animals; Excitatory Postsynaptic Potentials; Fluorometry; Hippocampus; In Vitro Techniques; Male; Neurons; Oxidative Stress; Purinergic P1 Receptor Antagonists; Pyrimidines; Rats; Rats, Wistar; Reactive Oxygen Species; Receptor, Adenosine A2A; Synaptic Transmission; Triazoles; Xanthines | 2003 |
Involvement of adenosine A1 and A2A receptors in the motor effects of caffeine after its acute and chronic administration.
Topics: Adenosine; Amphetamine; Animals; Behavior, Animal; Caffeine; Central Nervous System Stimulants; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Interactions; Male; Motor Activity; Phenethylamines; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Radioligand Assay; Rats; Rats, Sprague-Dawley; Receptor, Adenosine A2A; Receptors, Purinergic P1; Theophylline; Time Factors; Triazines; Triazoles; Tritium; Xanthines | 2003 |
A2A and A3 receptors mediate the adenosine-induced relaxation in spontaneously active possum duodenum in vitro.
Topics: Adenosine; Animals; Duodenum; Female; In Vitro Techniques; Male; Opossums; Purinergic P1 Receptor Antagonists; Pyrrolidinones; Quinazolines; Receptors, Purinergic P1; Tetrodotoxin; Time Factors; Triazoles; Xanthines | 2003 |
Enhanced adenosine A2A receptor facilitation of synaptic transmission in the hippocampus of aged rats.
Topics: Adenosine; Adrenergic beta-Agonists; Aging; Animals; Blotting, Western; Cyclic AMP; Electrophysiology; Excitatory Postsynaptic Potentials; Hippocampus; Isoproterenol; Male; Neurons; Phenethylamines; Presynaptic Terminals; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Rats; Rats, Wistar; Receptor, Adenosine A2A; Receptors, Purinergic P1; Synaptic Transmission; Triazines; Triazoles; Xanthines | 2003 |
Effects of adenosine receptor antagonists on pial arteriolar dilation during carbon dioxide inhalation.
Topics: Adenosine; Administration, Inhalation; Animals; Caffeine; Carbon Dioxide; Cerebral Cortex; Cerebral Veins; Cerebrovascular Circulation; Drug Interactions; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Purinergic P1 Receptor Antagonists; Quinazolines; Rats; Rats, Sprague-Dawley; Triazines; Triazoles; Vasodilation; Vasodilator Agents; Xanthines | 2003 |
Brief, repeated, oxygen-glucose deprivation episodes protect neurotransmission from a longer ischemic episode in the in vitro hippocampus: role of adenosine receptors.
Topics: Adenosine A1 Receptor Antagonists; Adenosine A2 Receptor Antagonists; Adenosine A3 Receptor Antagonists; Animals; Brain Ischemia; Electric Stimulation; Excitatory Postsynaptic Potentials; Glucose; Hippocampus; Hypoxia; In Vitro Techniques; Ischemic Preconditioning; Male; Oxygen; Purinergic P1 Receptor Antagonists; Pyridines; Rats; Rats, Wistar; Receptor, Adenosine A1; Receptor, Adenosine A2A; Receptor, Adenosine A3; Receptors, Purinergic P1; Synaptic Transmission; Time Factors; Triazines; Triazoles; Xanthines | 2003 |
Caffeine reduces hypnotic effects of alcohol through adenosine A2A receptor blockade.
Topics: Adenosine A1 Receptor Antagonists; Adenosine A2 Receptor Antagonists; Animals; Body Temperature; Caffeine; Central Nervous System Depressants; Central Nervous System Stimulants; Dipyridamole; Drug Overdose; Ethanol; Hypnotics and Sedatives; Male; Mice; Mice, Knockout; Neuroprotective Agents; Pentobarbital; Postural Balance; Pyrimidines; Receptor, Adenosine A2A; Triazoles; Vasodilator Agents; Xanthines | 2003 |
Adenosine administration produces an antidepressant-like effect in mice: evidence for the involvement of A1 and A2A receptors.
Topics: Adenosine; Animals; Antidepressive Agents; Caffeine; Depressive Disorder; Disease Models, Animal; Female; Male; Mice; Motor Activity; Receptor, Adenosine A1; Receptor, Adenosine A2A; Stress, Psychological; Triazines; Triazoles; Xanthines | 2004 |
Involvement of adenosine A1 receptors in forced walking stress-induced analgesia in mice.
Topics: Adenosine A1 Receptor Antagonists; Analgesia; Animals; Behavior, Animal; Formaldehyde; Male; Mice; Mice, Inbred Strains; Pain; Receptor, Adenosine A1; Stress, Psychological; Theophylline; Triazines; Triazoles; Walking; Xanthines | 2003 |
Role of adenosine A2A receptor in the regulation of gastric somatostatin release.
Topics: Adenosine; Adenosine A2 Receptor Agonists; Adenosine A2 Receptor Antagonists; Animals; Gastric Mucosa; Male; Phenethylamines; Rats; Rats, Wistar; Receptor, Adenosine A2A; Somatostatin; Stomach; Tissue Distribution; Triazines; Triazoles; Xanthines | 2004 |
Inosine stimulates chemotaxis, Ca2+-transients and actin polymerization in immature human dendritic cells via a pertussis toxin-sensitive mechanism independent of adenosine receptors.
Topics: Actins; Antigens, CD; Caffeine; Calcium; Cell Differentiation; Chemotaxis; Cytokines; Dendritic Cells; Dose-Response Relationship, Drug; Flow Cytometry; Histocompatibility Antigens Class I; Humans; Inosine; Pertussis Toxin; Purinergic P1 Receptor Antagonists; Quinazolines; Receptors, Purinergic P1; Triazoles; Xanthines | 2004 |
Binding of the prototypical adenosine A(2A) receptor agonist CGS 21680 to the cerebral cortex of adenosine A(1) and A(2A) receptor knockout mice.
Topics: Adenosine; Adenosine A1 Receptor Antagonists; Adenosine A2 Receptor Agonists; Animals; Autoradiography; Basal Ganglia; Binding, Competitive; Blotting, Western; Cerebral Cortex; Electrophoresis, Polyacrylamide Gel; Mice; Mice, Knockout; Models, Animal; Phenethylamines; Pyrimidines; Receptor, Adenosine A1; Receptor, Adenosine A2A; Triazoles; Tritium; Xanthines | 2004 |
Striatal adenosine A(2A) receptor blockade increases extracellular dopamine release following l-DOPA administration in intact and dopamine-denervated rats.
Topics: 3,4-Dihydroxyphenylacetic Acid; Adenosine A2 Receptor Antagonists; Analysis of Variance; Animals; Area Under Curve; Brain Chemistry; Chromatography, High Pressure Liquid; Corpus Striatum; Denervation; Dopamine; Dopamine Agents; Dose-Response Relationship, Drug; Drug Interactions; Extracellular Space; Homovanillic Acid; Hydroxyindoleacetic Acid; Levodopa; Male; Malonates; Methyltyrosines; Rats; Rats, Wistar; Receptor, Adenosine A2A; Reserpine; Serotonin; Substantia Nigra; Time Factors; Triazines; Triazoles; Xanthines | 2004 |
Adenosine A1 receptors modulate the anxiolytic-like effect of ethanol in the elevated plus-maze in mice.
Topics: Adenosine; Adenosine A1 Receptor Agonists; Adenosine A1 Receptor Antagonists; Adenosine A2 Receptor Antagonists; Analysis of Variance; Animals; Anti-Anxiety Agents; Anxiety; Caffeine; Dose-Response Relationship, Drug; Drug Synergism; Ethanol; Male; Maze Learning; Mice; Receptor, Adenosine A1; Triazines; Triazoles; Xanthines | 2004 |
Adenosine A1 receptor blockade mimics caffeine's attenuation of ethanol-induced motor incoordination.
Topics: Adenosine A1 Receptor Antagonists; Animals; Caffeine; Central Nervous System Depressants; Drug Interactions; Ethanol; Male; Motor Skills; Purinergic P1 Receptor Antagonists; Pyrimidines; Rats; Rats, Sprague-Dawley; Triazoles; Xanthines | 2004 |
Adenosine A2A-receptor blockade abolishes the roll-off respiratory response to hypoxia in awake lambs.
Topics: Adenosine A2 Receptor Antagonists; Animals; Animals, Newborn; Blood Pressure; Body Temperature; Carbon Dioxide; Heart Rate; Hydrogen-Ion Concentration; Hypoxia; Oxygen; Receptor, Adenosine A2A; Respiration; Sheep; Tidal Volume; Time Factors; Triazines; Triazoles; Xanthines | 2005 |
A2B adenosine receptor mediates human chorionic vasoconstriction and signals through arachidonic acid cascade.
Topics: Adenosine; Adenosine A2 Receptor Antagonists; Adenosine-5'-(N-ethylcarboxamide); Arachidonic Acid; Chorion; Endothelium, Vascular; Female; Humans; In Vitro Techniques; Placenta; Pregnancy; Receptor, Adenosine A2B; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Signal Transduction; Triazines; Triazoles; Vasoconstriction; Vasodilator Agents; Xanthines | 2005 |
In vivo adenosine receptor preconditioning reduces myocardial infarct size via subcellular ERK signaling.
Topics: Animals; Butadienes; Enzyme Inhibitors; Imidazoles; Ischemic Preconditioning, Myocardial; MAP Kinase Signaling System; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Myocardial Infarction; Nitriles; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Pyridines; Rats; Rats, Sprague-Dawley; Receptors, Purinergic P1; Reperfusion Injury; Subcellular Fractions; Triazines; Triazoles; Xanthines | 2005 |
Co-localization and functional interaction between adenosine A(2A) and metabotropic group 5 receptors in glutamatergic nerve terminals of the rat striatum.
Topics: Adenosine; Adenosine A2 Receptor Agonists; Adenosine A2 Receptor Antagonists; Animals; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Glutamic Acid; Male; Neostriatum; Phenethylamines; Presynaptic Terminals; Pyrimidines; Rats; Rats, Wistar; Receptor, Adenosine A2A; Receptor, Metabotropic Glutamate 5; Receptors, Metabotropic Glutamate; Subcellular Fractions; Synaptosomes; Triazoles; Xanthines | 2005 |
Adenosine contributes to mu-opioid synaptic inhibition in rat substantia gelatinosa in vitro.
Topics: Adenosine; Analgesics, Opioid; Animals; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Excitatory Postsynaptic Potentials; Neural Inhibition; Neurons; Organ Culture Techniques; Patch-Clamp Techniques; Rats; Receptors, Opioid, mu; Receptors, Purinergic P1; Substantia Gelatinosa; Synapses; Triazines; Triazoles; Xanthines | 2005 |
Modulation of short-term social memory in rats by adenosine A1 and A(2A) receptors.
Topics: Adenosine; Animals; Behavior, Animal; Brain; Caffeine; Dose-Response Relationship, Drug; Drug Administration Schedule; Injections, Intraperitoneal; Male; Memory, Short-Term; Rats; Rats, Wistar; Receptor, Adenosine A1; Receptor, Adenosine A2A; Social Behavior; Triazines; Triazoles; Xanthines | 2005 |
Adenosine agonist regulation of outward active transport of fluorescein across retinal pigment epithelium in rabbits.
Topics: Adenosine; Adenosine A1 Receptor Antagonists; Adenosine A2 Receptor Antagonists; Adenosine A3 Receptor Antagonists; Adenosine-5'-(N-ethylcarboxamide); Animals; Biological Transport, Active; Dihydropyridines; Fluorescein; Fluoresceins; Fluorophotometry; Injections, Intravenous; Male; Pigment Epithelium of Eye; Purinergic P1 Receptor Antagonists; Rabbits; Retinal Detachment; Triazines; Triazoles; Xanthines | 2005 |
Blockade of adenosine A2A receptors reverses short-term social memory impairments in spontaneously hypertensive rats.
Topics: Adenosine A2 Receptor Antagonists; Analysis of Variance; Animals; Caffeine; Discrimination Learning; Habituation, Psychophysiologic; Male; Memory Disorders; Memory, Short-Term; Rats; Rats, Inbred SHR; Rats, Wistar; Receptor, Adenosine A2A; Recognition, Psychology; Smell; Social Behavior; Social Environment; Species Specificity; Triazines; Triazoles; Xanthines | 2005 |
Activation of adenosine receptors in the posterior cingulate cortex impairs memory retrieval in the rat.
Topics: Adenosine; Animals; Avoidance Learning; Cerebral Cortex; Exploratory Behavior; Gyrus Cinguli; Male; Memory; Microinjections; Phenethylamines; Purinergic Agonists; Purinergic Antagonists; Rats; Rats, Wistar; Receptor, Adenosine A1; Receptor, Adenosine A2A; Triazines; Triazoles; Xanthines | 2005 |
Does conversion of ATP to adenosine terminate ATP-stimulated vasopressin release from hypothalamo-neurohypophyseal explants?
Topics: 5'-Nucleotidase; Adenosine; Adenosine A1 Receptor Antagonists; Adenosine Triphosphate; Animals; Enzyme Inhibitors; Hypothalamo-Hypophyseal System; Male; Organ Culture Techniques; Pituitary Gland, Posterior; Purinergic P1 Receptor Antagonists; Quinazolines; Rats; Rats, Sprague-Dawley; Receptor, Adenosine A1; Receptors, Purinergic P1; Supraoptic Nucleus; Time Factors; Triazoles; Vasopressins; Water-Electrolyte Balance; Xanthines | 2005 |
Postconditioning reduces infarct size via adenosine receptor activation by endogenous adenosine.
Topics: Adenosine; Animals; Male; Myocardial Infarction; Myocardial Reperfusion; Myocardium; Perfusion; Purinergic P1 Receptor Antagonists; Random Allocation; Rats; Rats, Sprague-Dawley; Receptors, Purinergic P1; Theophylline; Triazines; Triazoles; Xanthines | 2005 |
Modulation of seizures and synaptic plasticity by adenosinergic receptors in an experimental model of temporal lobe epilepsy induced by pilocarpine in rats.
Topics: 5'-Nucleotidase; Adenosine; Animals; Dentate Gyrus; Disease Models, Animal; Epilepsy, Temporal Lobe; Hippocampus; In Situ Nick-End Labeling; Male; Neuronal Plasticity; Neuroprotective Agents; Pilocarpine; Purinergic P1 Receptor Antagonists; Quinazolines; Rats; Rats, Wistar; Receptors, Purinergic P1; Status Epilepticus; Synapses; Triazoles; Xanthines | 2005 |
Dual presynaptic control by ATP of glutamate release via facilitatory P2X1, P2X2/3, and P2X3 and inhibitory P2Y1, P2Y2, and/or P2Y4 receptors in the rat hippocampus.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Adenylyl Imidodiphosphate; Animals; Astrocytoma; Calcium; Cell Line; Cell Line, Tumor; Glutamic Acid; Hippocampus; Kidney; Male; Potassium; Pyramidal Cells; Pyridoxal Phosphate; Rats; Rats, Wistar; Receptors, Presynaptic; Receptors, Purinergic P2; Receptors, Purinergic P2X; Receptors, Purinergic P2X2; Receptors, Purinergic P2X3; Receptors, Purinergic P2Y1; Receptors, Purinergic P2Y2; Recombinant Fusion Proteins; RNA, Messenger; Subcellular Fractions; Suramin; Synaptosomes; Transfection; Triazines; Triazoles; Xanthines | 2005 |
Combination of adenosine A1 and A2A receptor blocking agents induces caffeine-like locomotor stimulation in mice.
Topics: Adenosine A1 Receptor Antagonists; Adenosine A2 Receptor Antagonists; Animals; Brain Chemistry; Caffeine; Central Nervous System Stimulants; Dose-Response Relationship, Drug; Early Growth Response Protein 1; In Situ Hybridization; Male; Mice; Mice, Inbred C57BL; Motor Activity; Neuroprotective Agents; Pyrimidines; RNA, Messenger; Triazoles; Xanthines | 2006 |
The cellular mechanisms by which adenosine evokes release of nitric oxide from rat aortic endothelium.
Topics: Adenosine; Animals; Aorta, Thoracic; Apamin; Arachidonic Acids; Calcium; Endothelium, Vascular; In Vitro Techniques; Large-Conductance Calcium-Activated Potassium Channels; Male; Nitric Oxide; Peptides; Phospholipases A; Phospholipases A2; Rats; Rats, Wistar; Receptor, Adenosine A1; Receptors, Adenosine A2; Second Messenger Systems; Small-Conductance Calcium-Activated Potassium Channels; Triazines; Triazoles; Vasodilator Agents; Xanthines | 2006 |
Effects of the A 2A adenosine receptor antagonist KW6002 in the nucleus accumbens in vitro and in vivo.
Topics: Animals; Binding, Competitive; Conditioning, Operant; Dopamine; Dose-Response Relationship, Drug; Extracellular Space; gamma-Aminobutyric Acid; In Vitro Techniques; Male; Microdialysis; Motor Activity; Nucleus Accumbens; Purines; Rats; Receptor, Adenosine A2A; Triazines; Triazoles; Xanthines | 2006 |
Role of adenosine A1 receptors in the modulation of dopamine D1 and adenosine A2A receptor signaling in the neostriatum.
Topics: Adenosine; Adenosine A1 Receptor Agonists; Adenosine A1 Receptor Antagonists; Adenosine A2 Receptor Antagonists; Animals; Benzazepines; Dopamine and cAMP-Regulated Phosphoprotein 32; Dopamine Antagonists; Drug Interactions; Gene Expression; In Vitro Techniques; Mice; Mice, Inbred C57BL; Neostriatum; Phenethylamines; Raclopride; Receptor, Adenosine A1; Receptor, Adenosine A2A; Receptors, Dopamine D1; Signal Transduction; Threonine; Triazines; Triazoles; Xanthines | 2006 |
Evidence for both adenosine A1 and A2A receptors activating single vagal sensory C-fibres in guinea pig lungs.
Topics: Action Potentials; Adenosine; Adenosine A1 Receptor Antagonists; Adenosine A2 Receptor Antagonists; Animals; Capsaicin; Gene Expression Regulation; Guinea Pigs; Lung; Male; Nerve Fibers, Unmyelinated; Neurons; Nodose Ganglion; Patch-Clamp Techniques; Phenethylamines; Pyrimidines; Receptor, Adenosine A1; Receptors, Adenosine A2; RNA, Messenger; Triazoles; Xanthines | 2006 |
Increased density and synapto-protective effect of adenosine A2A receptors upon sub-chronic restraint stress.
Topics: Analysis of Variance; Animals; Blotting, Western; Dose-Response Relationship, Drug; Gene Expression Regulation; Hippocampus; Immunohistochemistry; Male; Neuroprotective Agents; Protein Binding; Pyrimidines; Rats; Rats, Wistar; Receptor, Adenosine A1; Receptor, Adenosine A2A; Restraint, Physical; Stress, Psychological; Synapses; Synaptophysin; Triazoles; Tritium; Xanthines | 2006 |
Caffeine inhibition of rat carotid body chemoreceptors is mediated by A2A and A2B adenosine receptors.
Topics: Adenosine; Animals; Caffeine; Carotid Body; Catecholamines; Central Nervous System Stimulants; Chemoreceptor Cells; Dose-Response Relationship, Drug; Female; Hypoxia; Immunohistochemistry; Male; Potassium; Rats; Rats, Wistar; Receptor, Adenosine A2A; Receptor, Adenosine A2B; Receptors, Presynaptic; Respiratory Mechanics; Triazines; Triazoles; Xanthines | 2006 |
Inhibitory responses to exogenous adenosine in murine proximal and distal colon.
Topics: Adenosine; Animals; Colon; Dose-Response Relationship, Drug; Enzyme Inhibitors; Male; Mice; Mice, Inbred C57BL; Muscle Contraction; Muscle, Smooth; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase Type III; Purinergic P1 Receptor Antagonists; Quinazolines; Receptors, Purinergic P1; Signal Transduction; Theobromine; Triazoles; Xanthines | 2006 |
ST 1535: a preferential A2A adenosine receptor antagonist.
Topics: Adenine; Adenosine A2 Receptor Antagonists; Animals; Behavior, Animal; Catalepsy; CHO Cells; Cricetinae; Cricetulus; Cyclic AMP; Dose-Response Relationship, Drug; Drug Interactions; Humans; Inhibitory Concentration 50; Male; Mice; Motor Activity; Radioligand Assay; Time Factors; Transfection; Triazoles; Tritium; Xanthines | 2006 |
Tonic adenosine A1 and A2A receptor activation is required for the excitatory action of VIP on synaptic transmission in the CA1 area of the hippocampus.
Topics: Adenosine; Adenosine Deaminase; Analysis of Variance; Animals; Drug Interactions; Electric Stimulation; Excitatory Postsynaptic Potentials; Hippocampus; In Vitro Techniques; Male; Membrane Potentials; Neuroprotective Agents; Patch-Clamp Techniques; Pyrimidines; Rats; Rats, Wistar; Receptor, Adenosine A1; Receptor, Adenosine A2A; Synaptic Transmission; Triazines; Triazoles; Vasoactive Intestinal Peptide; Xanthines | 2007 |
ZM241385, DPCPX, MRS1706 are inverse agonists with different relative intrinsic efficacies on constitutively active mutants of the human adenosine A2B receptor.
Topics: Adenosine A2 Receptor Agonists; Humans; Mutation; Purines; Saccharomyces cerevisiae; Triazines; Triazoles; Xanthines | 2007 |
Disruption of adenosinergic modulation of ventilation at rest and during hypercapnia by neonatal caffeine in young rats: role of adenosine A(1) and A(2A) receptors.
Topics: Adenosine A1 Receptor Antagonists; Adenosine A2 Receptor Antagonists; Animals; Caffeine; Central Nervous System Stimulants; Hypercapnia; Injections, Intraperitoneal; Male; Plethysmography; Pulmonary Ventilation; Rats; Rats, Sprague-Dawley; Receptor, Adenosine A1; Receptor, Adenosine A2A; Rest; Time Factors; Triazines; Triazoles; Xanthines | 2007 |
Endogenous expression of adenosine A1, A2 and A3 receptors in rat C6 glioma cells.
Topics: Adenylyl Cyclases; Animals; Blotting, Western; Brain Neoplasms; Cell Line, Tumor; Cell Membrane; Fluorescent Antibody Technique; Glioma; GTP-Binding Protein alpha Subunits, Gi-Go; GTP-Binding Protein alpha Subunits, Gs; Molecular Sequence Data; Nerve Tissue Proteins; Protein Binding; Rats; Receptor, Adenosine A1; Receptor, Adenosine A3; Receptors, Adenosine A2; Reverse Transcriptase Polymerase Chain Reaction; Triazines; Triazoles; Xanthines | 2007 |
Combined antagonism of glutamate mGlu5 and adenosine A2A receptors interact to regulate alcohol-seeking in rats.
Topics: Adenosine; Adenosine A1 Receptor Antagonists; Adenosine A2 Receptor Antagonists; Alcohol Drinking; Animals; Behavior, Animal; Central Nervous System Depressants; Conditioning, Operant; Cues; Dose-Response Relationship, Drug; Ethanol; Extinction, Psychological; Glutamic Acid; Models, Animal; Motor Activity; Pyridines; Pyrimidines; Rats; Rats, Inbred Strains; Reaction Time; Receptor, Adenosine A1; Receptor, Adenosine A2A; Receptor, Metabotropic Glutamate 5; Receptors, Metabotropic Glutamate; Self Administration; Thiazoles; Time Factors; Triazoles; Xanthines | 2008 |
Indomethacin stimulates activity and expression of ecto-5'-nucleotidase/CD73 in glioma cell lines.
Topics: 5'-Nucleotidase; Actins; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Anti-Inflammatory Agents, Non-Steroidal; Cell Line, Tumor; Cell Proliferation; Dimethyl Sulfoxide; Dose-Response Relationship, Drug; Enzyme Activation; Flow Cytometry; Gene Expression Regulation, Enzymologic; Glioma; Humans; Indomethacin; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Quinazolines; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Theophylline; Time Factors; Triazoles; Xanthines | 2007 |
Stimulation of adenosine A2A receptor inhibits LPS-induced expression of intercellular adhesion molecule 1 and production of TNF-alpha in human peripheral blood mononuclear cells.
Topics: Adenosine; Adenosine A1 Receptor Agonists; Adenosine A1 Receptor Antagonists; Adenosine A2 Receptor Agonists; Adenosine A2 Receptor Antagonists; Adenosine A3 Receptor Agonists; Adenosine A3 Receptor Antagonists; CD40 Antigens; Cells, Cultured; Cyclic AMP; Enzyme-Linked Immunosorbent Assay; Flavins; Flow Cytometry; Humans; Intercellular Adhesion Molecule-1; Leukocytes, Mononuclear; Lipopolysaccharide Receptors; Lipopolysaccharides; Receptor, Adenosine A2A; Triazines; Triazoles; Tumor Necrosis Factor-alpha; Xanthines | 2008 |
Purinergic modulation of glutamate release under ischemic-like conditions in the hippocampus.
Topics: Adenosine; Adenosine Triphosphate; Analgesics; Animals; Dose-Response Relationship, Drug; Glucose; Glutamic Acid; Hippocampus; Hypoxia; In Vitro Techniques; Ischemia; Male; Phenethylamines; Purinergic Agonists; Purinergic Antagonists; Pyrimidines; Rats; Rats, Wistar; Receptors, Purinergic; Sodium Channel Blockers; Tetrodotoxin; Triazines; Triazoles; Xanthines | 2007 |
Up-regulation of adenosine receptors in the frontal cortex in Alzheimer's disease.
Topics: Adenylyl Cyclases; Aged; Aged, 80 and over; Alzheimer Disease; Analysis of Variance; Cell Membrane; Colforsin; Cyclic AMP; Female; Frontal Lobe; Guanosine 5'-O-(3-Thiotriphosphate); Humans; Male; Middle Aged; Protein Binding; Receptors, Purinergic P1; Triazines; Triazoles; Tritium; Up-Regulation; Xanthines | 2008 |
Involvement of the adenosine A1 and A2A receptors in the antidepressant-like effect of zinc in the forced swimming test.
Topics: Adenosine; Adenosine A1 Receptor Agonists; Adenosine A2 Receptor Agonists; Aniline Compounds; Animals; Antidepressive Agents; Caffeine; Central Nervous System Stimulants; Dipyridamole; Female; Male; Mice; Motor Activity; Nucleoside Transport Proteins; Receptor, Adenosine A1; Receptor, Adenosine A2A; Swimming; Triazines; Triazoles; Xanthines; Zinc | 2008 |
Hypotensive effects of intravenously administered uridine and cytidine in conscious rats: involvement of adenosine receptors.
Topics: Adenosine; Adenosine A1 Receptor Agonists; Adenosine A2 Receptor Agonists; Animals; Antihypertensive Agents; Blood Pressure; Caffeine; Carotid Arteries; Consciousness; Cytidine; Dose-Response Relationship, Drug; Heart Rate; Hypotension; Injections, Intravenous; Injections, Intraventricular; Male; Rats; Rats, Wistar; Receptor, Adenosine A1; Receptor, Adenosine A2A; Theobromine; Theophylline; Time Factors; Triazines; Triazoles; Uridine; Ventricular Function, Left; Ventricular Pressure; Xanthines | 2008 |
Caffeine and a selective adenosine A(2B) receptor antagonist but not imidazoline receptor antagonists modulate antinociception induced by diphenyl diselenide in mice.
Topics: Adrenergic alpha-Antagonists; Animals; Behavior, Animal; Benzene Derivatives; Benzofurans; Caffeine; Disease Models, Animal; Dose-Response Relationship, Drug; Hyperalgesia; Imidazoles; Injections, Intraperitoneal; Male; Mice; Neuroprotective Agents; Organoselenium Compounds; Pain Measurement; Phosphodiesterase Inhibitors; Pyrimidines; Triazoles; Xanthines | 2008 |
Inosine and equilibrative nucleoside transporter 2 contribute to hypoxic preconditioning in the murine cardiomyocyte HL-1 cell line.
Topics: Adenosine; Adenosine A1 Receptor Antagonists; Adenosine A3 Receptor Antagonists; Animals; Cell Hypoxia; Cell Line; Cell Survival; Equilibrative Nucleoside Transporter 1; Equilibrative-Nucleoside Transporter 2; Inosine; Mice; Myocytes, Cardiac; Nucleoside Transport Proteins; Quinazolines; Receptor, Adenosine A1; Receptor, Adenosine A3; Thioinosine; Triazoles; Up-Regulation; Xanthines | 2008 |
Synthesis, ligand-receptor modeling studies and pharmacological evaluation of novel 4-modified-2-aryl-1,2,4-triazolo[4,3-a]quinoxalin-1-one derivatives as potent and selective human A3 adenosine receptor antagonists.
Topics: Adenosine A3 Receptor Antagonists; Animals; Binding, Competitive; Brain Ischemia; Cattle; Cell Membrane; Cerebral Cortex; Disease Models, Animal; Humans; Hydrogen Bonding; Ligands; Models, Molecular; Protein Binding; Quinoxalines; Rats; Receptor, Adenosine A3; Rhodopsin; Structural Homology, Protein; Structure-Activity Relationship; Triazoles; Xanthines | 2008 |
The effects of adenosine A2A receptor antagonists on haloperidol-induced movement disorders in primates.
Topics: Adenosine A2 Receptor Antagonists; Animals; Antipsychotic Agents; Caffeine; Catalepsy; Cebus; Corpus Striatum; Disease Models, Animal; Dose-Response Relationship, Drug; Dyskinesia, Drug-Induced; gamma-Aminobutyric Acid; Globus Pallidus; Haloperidol; Neurologic Examination; Purines; Pyrimidines; Receptor, Adenosine A2A; Saimiri; Triazoles; Xanthines | 2008 |
Adenosine receptor subtypes in the airways responses to 5'-adenosine monophosphate inhalation of sensitized guinea-pigs.
Topics: Adenosine Monophosphate; Administration, Inhalation; Animals; Anti-Inflammatory Agents; Asthma; Bronchial Hyperreactivity; Bronchoalveolar Lavage Fluid; Bronchoconstriction; Bronchodilator Agents; Dexamethasone; Dose-Response Relationship, Drug; Guinea Pigs; Immunization; Purinergic P1 Receptor Antagonists; Purines; Quinazolines; Receptors, Purinergic P1; Triazines; Triazoles; Xanthines | 2008 |
Adenosine receptor antagonists alter the stability of human epileptic GABAA receptors.
Topics: Adenosine; Adenosine Deaminase; Adult; Animals; Anticonvulsants; Cerebral Cortex; Epilepsy; Female; GABA-A Receptor Agonists; gamma-Aminobutyric Acid; Humans; Male; Neurons; Oocytes; Purinergic P1 Receptor Antagonists; Pyramidal Tracts; Pyrimidines; Quinazolines; Rats; Receptors, GABA-A; Triazoles; Xanthines; Xenopus | 2008 |
Caffeine modulates TNF-alpha production by cord blood monocytes: the role of adenosine receptors.
Topics: Acetamides; Adenosine A1 Receptor Antagonists; Adenosine A2 Receptor Antagonists; Adenosine A3 Receptor Antagonists; Adult; Blotting, Western; Caffeine; Cells, Cultured; Cyclic AMP; Dose-Response Relationship, Drug; Enzyme-Linked Immunosorbent Assay; Fetal Blood; Humans; Infant, Newborn; Interleukins; Lipopolysaccharides; Middle Aged; Monocytes; Purines; Quinazolines; Receptor, Adenosine A1; Receptor, Adenosine A2A; Receptor, Adenosine A2B; Receptor, Adenosine A3; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Time Factors; Triazines; Triazoles; Tumor Necrosis Factor-alpha; Xanthines | 2009 |
Adenosine A1 and A2a receptors modulate insulinemia, glycemia, and lactatemia in fetal sheep.
Topics: Adenosine; Adenosine A1 Receptor Antagonists; Adenosine A2 Receptor Antagonists; Animals; Blood Gas Analysis; Blood Glucose; Female; Fetus; Hydrogen-Ion Concentration; Hypoxia; Insulin; Lactates; Pregnancy; Receptor, Adenosine A1; Receptor, Adenosine A2A; Sheep; Triazines; Triazoles; Xanthines | 2009 |
Anti-nociceptive properties of the xanthine oxidase inhibitor allopurinol in mice: role of A1 adenosine receptors.
Topics: Adenosine; Adenosine A1 Receptor Agonists; Adenosine A1 Receptor Antagonists; Adenosine A2 Receptor Antagonists; Allopurinol; Analgesics; Animals; Capsaicin; Dose-Response Relationship, Drug; Glutamic Acid; Hot Temperature; Injections, Intraperitoneal; Male; Mice; Naloxone; Narcotic Antagonists; Pain; Pain Measurement; Pyrimidines; Triazoles; Uric Acid; Xanthine Oxidase; Xanthines | 2009 |
Adenosine A(1) and A(2A) receptors in mouse prefrontal cortex modulate acetylcholine release and behavioral arousal.
Topics: Acetylcholine; Adenosine; Adenosine A1 Receptor Antagonists; Adenosine A2 Receptor Antagonists; Analysis of Variance; Animals; Arousal; Behavior, Animal; Caffeine; Chromatography, High Pressure Liquid; Electroencephalography; Electromyography; Male; Mice; Microdialysis; Phenethylamines; Phosphodiesterase Inhibitors; Prefrontal Cortex; Receptor, Adenosine A1; Receptors, Adenosine A2; Spectrum Analysis; Triazines; Triazoles; Xanthines | 2009 |
Caffeine and a selective adenosine A2A receptor antagonist induce reward and sensitization behavior associated with increased phospho-Thr75-DARPP-32 in mice.
Topics: Adenosine A2 Receptor Antagonists; Animals; Blotting, Western; Caffeine; Conditioning, Operant; Dopamine and cAMP-Regulated Phosphoprotein 32; Dose-Response Relationship, Drug; Male; Mice; Mice, Inbred C57BL; Neuroprotective Agents; Phosphodiesterase Inhibitors; Purinergic P1 Receptor Antagonists; Pyrimidines; Reward; Triazoles; Xanthines | 2009 |
Adenosine receptor antagonists improve short-term object-recognition ability of spontaneously hypertensive rats: a rodent model of attention-deficit hyperactivity disorder.
Topics: Adenosine A1 Receptor Antagonists; Adenosine A2 Receptor Antagonists; Animals; Attention Deficit Disorder with Hyperactivity; Blood Pressure; Caffeine; Disease Models, Animal; Female; Male; Memory, Short-Term; Methylphenidate; Rats; Rats, Inbred SHR; Rats, Wistar; Receptor, Adenosine A1; Receptors, Adenosine A2; Recognition, Psychology; Triazines; Triazoles; Xanthines | 2009 |
Cardioprotection induced by adenosine A1 receptor agonists in a cardiac cell ischemia model involves cooperative activation of adenosine A2A and A2B receptors by endogenous adenosine.
Topics: Acetamides; Adenosine; Adenosine A1 Receptor Agonists; Adenosine A2 Receptor Agonists; Adenosine A2 Receptor Antagonists; Adenosine A3 Receptor Agonists; Adenosine A3 Receptor Antagonists; Aminopyridines; Animals; Apoptosis; Cardiotonic Agents; Cell Line; Cell Survival; Dihydropyridines; Imidazoles; Myocardial Ischemia; Phenethylamines; Purines; Rats; Triazines; Triazoles; Xanthines | 2009 |
Adenosine A1 receptors presynaptically modulate excitatory synaptic input onto subiculum neurons.
Topics: Action Potentials; Adenosine; Adenosine A1 Receptor Agonists; Adenosine A1 Receptor Antagonists; Adenosine A2 Receptor Agonists; Adenosine A2 Receptor Antagonists; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Central Nervous System Agents; Excitatory Postsynaptic Potentials; Hippocampus; In Vitro Techniques; Membrane Potentials; Neurons; Presynaptic Terminals; Pyramidal Cells; Rats; Rats, Sprague-Dawley; Receptor, Adenosine A1; Receptors, Adenosine A2; Synapses; Synaptic Transmission; Triazines; Triazoles; Xanthines | 2009 |
Absence of adenosine-mediated aortic relaxation in A(2A) adenosine receptor knockout mice.
Topics: Acetylcholine; Adenosine; Adenosine-5'-(N-ethylcarboxamide); Aminopyridines; Animals; Aorta; Dose-Response Relationship, Drug; Endothelium, Vascular; Female; Flavins; Gene Expression Regulation; In Vitro Techniques; Male; Mice; Mice, Knockout; Phenethylamines; Pyrimidines; Receptor, Adenosine A1; Receptor, Adenosine A2A; Receptor, Adenosine A2B; Triazoles; Vasoconstriction; Vasoconstrictor Agents; Vasodilation; Vasodilator Agents; Xanthines | 2009 |
Caffeine and an adenosine A(2A) receptor antagonist prevent memory impairment and synaptotoxicity in adult rats triggered by a convulsive episode in early life.
Topics: Adenosine A2 Receptor Antagonists; Analysis of Variance; Animals; Animals, Newborn; Caffeine; Disease Models, Animal; Disease Progression; Drug Administration Schedule; Glial Fibrillary Acidic Protein; Kainic Acid; Memory Disorders; Neurotoxicity Syndromes; Phosphodiesterase Inhibitors; Purines; Pyrimidines; Qa-SNARE Proteins; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; Seizures; Synapses; Synaptophysin; Synaptosomal-Associated Protein 25; Triazoles; Tritium; Xanthines | 2010 |
Oral tremor induced by the muscarinic agonist pilocarpine is suppressed by the adenosine A2A antagonists MSX-3 and SCH58261, but not the adenosine A1 antagonist DPCPX.
Topics: Adenosine A1 Receptor Antagonists; Adenosine A2 Receptor Antagonists; Animals; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Interactions; Jaw; Male; Muscarinic Agonists; Pilocarpine; Pimozide; Pyrimidines; Radioligand Assay; Rats; Rats, Sprague-Dawley; Tremor; Triazoles; Xanthines | 2010 |
The stimulatory effects of caffeine with oseltamivir (Tamiflu) on light-dark behavior and open-field behavior in mice.
Topics: Adenosine A1 Receptor Antagonists; Adenosine A2 Receptor Antagonists; Animals; Antiviral Agents; Caffeine; Darkness; Dopamine Antagonists; Dopamine D2 Receptor Antagonists; Exploratory Behavior; Flumazenil; GABA Modulators; GABA-A Receptor Antagonists; Haloperidol; Male; Mice; Motor Activity; Neurotransmitter Agents; Oseltamivir; Pyrimidines; Random Allocation; Triazoles; Xanthines | 2010 |
Caffeine and a selective adenosine A2A receptor antagonist induce sensitization and cross-sensitization behavior associated with increased striatal dopamine in mice.
Topics: 3,4-Dihydroxyphenylacetic Acid; Adenosine A2 Receptor Antagonists; Animals; Caffeine; Dopamine; Homovanillic Acid; Male; Mice; Mice, Inbred BALB C; Neostriatum; Neuroprotective Agents; Phosphorylation; Pyrimidines; Serine; Triazoles; Tyrosine 3-Monooxygenase; Xanthines | 2010 |
Adenosine inhibits paraventricular pre-sympathetic neurons through ATP-dependent potassium channels.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Action Potentials; Adenosine; Analgesics; Animals; Bicuculline; Dose-Response Relationship, Drug; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; GABA Antagonists; Glyburide; Guanosine Diphosphate; In Vitro Techniques; KATP Channels; Male; Membrane Potentials; Neurons; Paraventricular Hypothalamic Nucleus; Patch-Clamp Techniques; Potassium Channel Blockers; Rats; Rats, Sprague-Dawley; Receptor, Adenosine A1; Sodium Channel Blockers; Tetrodotoxin; Thionucleotides; Tolbutamide; Triazines; Triazoles; Xanthines | 2010 |
Adenosine activates a2b receptors and enhances chloride secretion in kidney inner medullary collecting duct cells.
Topics: Adenosine; Animals; Cell Line; Chlorides; Cystic Fibrosis Transmembrane Conductance Regulator; Kidney Medulla; Kidney Tubules, Collecting; Pyrazoles; Pyrimidines; Rats; Receptor, Adenosine A2B; Triazines; Triazoles; Xanthines | 2010 |
Glutamate-induced depression of EPSP-spike coupling in rat hippocampal CA1 neurons and modulation by adenosine receptors.
Topics: Adenosine A1 Receptor Antagonists; Adenosine Deaminase; Animals; CA1 Region, Hippocampal; Drug Interactions; Excitatory Amino Acid Agents; Excitatory Postsynaptic Potentials; Glutamic Acid; In Vitro Techniques; Male; Neural Inhibition; Neurons; Neuroprotective Agents; Probability; Pyrimidines; Rats; Rats, Wistar; Receptor, Adenosine A1; Receptors, N-Methyl-D-Aspartate; Triazoles; Xanthines | 2010 |
Cooperative cardioprotection through adenosine A1 and A2A receptor agonism in ischemia-reperfused isolated mouse heart.
Topics: Acetamides; Adenosine; Adenosine A1 Receptor Agonists; Adenosine A1 Receptor Antagonists; Adenosine A2 Receptor Agonists; Adenosine A2 Receptor Antagonists; Animals; Blood Pressure; Cardiotonic Agents; Drug Synergism; In Vitro Techniques; Male; Mice; Mice, Knockout; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Myocardial Contraction; Myocardial Reperfusion Injury; Phosphorylation; Purines; Receptor, Adenosine A2A; Triazines; Triazoles; Xanthines | 2010 |
Enhanced role of adenosine A(2A) receptors in the modulation of LTP in the rat hippocampus upon ageing.
Topics: Adenosine; Adenosine A1 Receptor Antagonists; Adenosine A2 Receptor Antagonists; Aging; Animals; Electrophysiology; Excitatory Postsynaptic Potentials; Glutamic Acid; Hippocampus; Long-Term Potentiation; Male; Memory Disorders; N-Methylaspartate; Neuronal Plasticity; Pyrimidines; Rats; Rats, Wistar; Receptor, Adenosine A1; Receptor, Adenosine A2A; Synaptic Transmission; Triazoles; Xanthines | 2011 |
[Sedative, hypnotic and anticonvulsive effects of an adenosine analogue WS090501].
Topics: Adenosine; Adenosine A1 Receptor Antagonists; Adenosine A2 Receptor Antagonists; Animals; Anticonvulsants; Convulsants; Electroencephalography; Hypnotics and Sedatives; Male; Mice; Mice, Inbred ICR; Motor Activity; Pentylenetetrazole; Pyrimidines; Rats; Rats, Wistar; Seizures; Sleep; Triazoles; Xanthines | 2011 |
A novel dihydro-pyrazolo(3,4d)(1,2,4)triazolo(1,5a)pyrimidin-4-one (AJ23) is an antagonist at adenosine A(1) receptors and enhances consolidation of step-down avoidance.
Topics: Adenosine; Analysis of Variance; Animals; Avoidance Learning; CA1 Region, Hippocampal; CHO Cells; Cricetinae; Cricetulus; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Interactions; Electric Stimulation; Excitatory Postsynaptic Potentials; HEK293 Cells; Heterocyclic Compounds, 3-Ring; Humans; In Vitro Techniques; Inhibition, Psychological; Male; Protein Binding; Purinergic P1 Receptor Antagonists; Pyrimidines; Rats; Rats, Wistar; Reaction Time; Retention, Psychology; Structure-Activity Relationship; Triazines; Triazoles; Tritium; Xanthines | 2012 |
Effects of ethanolic extract and naphthoquinones obtained from the bulbs of Cipura paludosa on short-term and long-term memory: involvement of adenosine A₁ and A₂A receptors.
Topics: Animals; Avoidance Learning; Brazil; Caffeine; Ethanol; Furans; Iridaceae; Male; Memory, Long-Term; Memory, Short-Term; Mice; Naphthoquinones; Plant Extracts; Plant Roots; Purinergic P1 Receptor Antagonists; Rats; Rats, Wistar; Receptor, Adenosine A1; Receptors, Adenosine A2; Triazines; Triazoles; Xanthines | 2013 |
High-intensity swimming exercise reduces neuropathic pain in an animal model of complex regional pain syndrome type I: evidence for a role of the adenosinergic system.
Topics: Adenine; Adenosine; Adenosine A1 Receptor Antagonists; Adenosine A2 Receptor Antagonists; Adenosine Deaminase Inhibitors; Animals; Caffeine; Exercise Therapy; Hyperalgesia; Male; Mice; Naloxone; Narcotic Antagonists; Neuralgia; Neurons; Reflex Sympathetic Dystrophy; Swimming; Triazines; Triazoles; Xanthines | 2013 |
Reduced striatal adenosine A2A receptor levels define a molecular subgroup in schizophrenia.
Topics: Actins; Adenosine A1 Receptor Antagonists; Adult; Aged; Aged, 80 and over; Alzheimer Disease; Cell Membrane; DNA Methylation; Female; Humans; Lewy Body Disease; Male; Middle Aged; Positron-Emission Tomography; Postmortem Changes; Psychiatric Status Rating Scales; Putamen; Receptor, Adenosine A2A; Schizophrenia; Triazines; Triazoles; Tritium; Xanthines | 2014 |
Sensorimotor gating is disrupted by acute but not chronic systemic exposure to caffeine in mice.
Topics: Adenosine A1 Receptor Antagonists; Adenosine A2 Receptor Antagonists; Animals; Caffeine; Central Nervous System Stimulants; Male; Mice; Mice, Inbred C57BL; Prepulse Inhibition; Purinergic P1 Receptor Antagonists; Pyrimidines; Sensory Gating; Triazoles; Xanthines | 2014 |
Methylxanthine reversal of opioid-induced respiratory depression in the neonatal rat: mechanism and location of action.
Topics: Adenosine A1 Receptor Antagonists; Adenosine A2 Receptor Antagonists; Animals; Animals, Newborn; Apnea; Brain Stem; Carotid Body; Central Nervous System Stimulants; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Phrenic Nerve; Quinazolines; Rats, Sprague-Dawley; Respiration; Theobromine; Theophylline; Tissue Culture Techniques; Triazoles; Xanthines | 2014 |
Dual blockade of the A1 and A2A adenosine receptor prevents amyloid beta toxicity in neuroblastoma cells exposed to aluminum chloride.
Topics: Adenosine A1 Receptor Antagonists; Adenosine A2 Receptor Antagonists; Aluminum Chloride; Aluminum Compounds; Amyloid beta-Peptides; Apoptosis; Astringents; Blotting, Western; Caffeine; Cell Proliferation; Cells, Cultured; Chlorides; Humans; Lipid Peroxidation; Neuroblastoma; Neuroprotective Agents; Oxidative Stress; Purinergic P1 Receptor Antagonists; Pyrimidines; Reactive Oxygen Species; Receptor, Adenosine A1; Receptor, Adenosine A2A; RNA, Small Interfering; Triazoles; Xanthines | 2014 |
Adenosine A(2A) receptors are necessary and sufficient to trigger memory impairment in adult mice.
Topics: Adenosine; Animals; Avoidance Learning; Dose-Response Relationship, Drug; Infusions, Intraventricular; Locomotion; Male; Maze Learning; Memory Disorders; Memory, Short-Term; Mice; Phenethylamines; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Pyrimidines; Receptor, Adenosine A1; Receptor, Adenosine A2A; Recognition, Psychology; Scopolamine; Triazoles; Xanthines | 2015 |
Mass spectrometry-based ligand binding assays on adenosine A1 and A2A receptors.
Topics: Animals; Cell Membrane; CHO Cells; Cricetinae; Cricetulus; Deuterium; Humans; Isotope Labeling; Ligands; Mass Spectrometry; Radioligand Assay; Receptor, Adenosine A1; Receptor, Adenosine A2A; Receptors, G-Protein-Coupled; Reference Standards; Reproducibility of Results; Triazines; Triazoles; Xanthines | 2015 |
[Central-adenosine A1 receptor involved in the thermal regulation effect of YZG-330, a N6-substituted adenosine derivative, in mice].
Topics: Adenosine; Adenosine A1 Receptor Antagonists; Animals; Body Temperature Regulation; Mice; Pyrimidines; Receptor, Adenosine A1; Triazoles; Xanthines | 2015 |
Paracrine effect of carbon monoxide - astrocytes promote neuroprotection through purinergic signaling in mice.
Topics: Adenosine; Adenosine Triphosphate; Animals; Apoptosis; Astrocytes; Carbon Monoxide; Coculture Techniques; Cysteine; Extracellular Space; Gene Silencing; Glycyrrhetinic Acid; Mice, Inbred C57BL; Models, Biological; Neurons; Neuroprotection; Paracrine Communication; Pyrimidines; Receptor, trkB; Receptors, Adenosine A2; Receptors, Purinergic; Serine; Signal Transduction; Suramin; Thioinosine; Triazoles; Xanthines | 2016 |
Theacrine: A purine alkaloid from Camellia assamica var. kucha with a hypnotic property via the adenosine system.
Topics: Adenosine; Alkaloids; Animals; Caffeine; Camellia; Drug Synergism; Hippocampus; Male; Mice; Pentobarbital; Pyrimidines; Rats; Sleep Initiation and Maintenance Disorders; Sleep Stages; Triazoles; Uric Acid; Xanthines | 2017 |
Adenosine Receptors Modulate the Exogenous Ketogenic Supplement-Evoked Alleviating Effect on Lipopolysaccharide-Generated Increase in Absence Epileptic Activity in WAG/Rij Rats.
Topics: 3-Hydroxybutyric Acid; Animals; Blood Glucose; Body Weight; Dietary Supplements; Disease Models, Animal; Epilepsy, Absence; Injections, Intraperitoneal; Ketones; Ketosis; Lipopolysaccharides; Purinergic P1 Receptor Antagonists; Pyrimidines; Rats; Rats, Wistar; Receptors, Purinergic P1; Triazoles; Xanthines | 2021 |