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triazoles and 1-(3-chlorophenyl)piperazine

triazoles has been researched along with 1-(3-chlorophenyl)piperazine in 14 studies

Research

Studies (14)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's12 (85.71)18.2507
2000's2 (14.29)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Barbhaiya, RH; Behr, DA; Greene, DS; Natarajan, CS; Sainati, SM; Shukla, UA1
Bernard, N; Cuisinaud, G; Ferry, N; Rougier, P; Sassard, J; Trepo, C1
Barbhaiya, RH; Kaul, S; Shukla, UA1
Barbhaiya, RH; Greene, DS; Shukla, UA2
Barbhaiya, RH; Gammans, RR; Greene, DS; Marathe, PH; Mayol, RF; Pittman, KA; Robinson, D; Shukla, UA1
Barbhaiya, RH; Brennan, J; Greene, DS; Marathe, PH; Salazar, DE; Shukla, UA1
Barbhaiya, RH; Brady, ME; Greene, DS; Shukla, UA1
Barbhaiya, RH; Buch, AB; Greene, DS1
Shah, VR; Shyu, WC; Srinivas, NR; Yao, M1
Caccia, S; Cervo, L; Fracasso, C; Guiso, G; Nacca, A1
Granda, BW; Grassi, JM; Greenblatt, DJ; Harmatz, JS; Schmider, J; Shader, RI; von Moltke, LL1
Srinivas, NR; Yao, M1
Huang, MQ; Jemal, M; Mao, Y; Xia, YQ1

Trials

5 trial(s) available for triazoles and 1-(3-chlorophenyl)piperazine

ArticleYear
Influence of hepatic impairment on the pharmacokinetics of nefazodone and two of its metabolites after single and multiple oral doses.
    Fundamental & clinical pharmacology, 1994, Volume: 8, Issue:5

    Topics: Adolescent; Adult; Antidepressive Agents; Female; Humans; Liver Diseases; Male; Middle Aged; Piperazines; Triazoles

1994
Lack of interaction between nefazodone and cimetidine: a steady state pharmacokinetic study in humans.
    British journal of clinical pharmacology, 1995, Volume: 40, Issue:2

    Topics: Administration, Oral; Adult; Analysis of Variance; Antidepressive Agents; Chromatography, High Pressure Liquid; Cimetidine; Cross-Over Studies; Drug Interactions; Histamine H2 Antagonists; Humans; Male; Piperazines; Serotonin Receptor Agonists; Triazoles

1995
Safety, tolerance, and preliminary pharmacokinetics of nefazodone after administration of single and multiple oral doses to healthy adult male volunteers: a double-blind, phase I study.
    Journal of clinical pharmacology, 1995, Volume: 35, Issue:10

    Topics: Administration, Oral; Adult; Antidepressive Agents, Second-Generation; Double-Blind Method; Drug Administration Schedule; Drug Tolerance; Humans; Male; Middle Aged; Piperazines; Triazoles

1995
Absorption and presystemic metabolism of nefazodone administered at different regions in the gastrointestinal tract of humans.
    Pharmaceutical research, 1995, Volume: 12, Issue:11

    Topics: Adult; Antidepressive Agents, Second-Generation; Biological Availability; Chromatography, High Pressure Liquid; Cross-Over Studies; Digestive System; Humans; Intestinal Absorption; Intubation, Gastrointestinal; Male; Piperazines; Serotonin Receptor Agonists; Spectrophotometry, Ultraviolet; Triazoles

1995
Single and multiple dose pharmacokinetics of nefazodone in subjects classified as extensive and poor metabolizers of dextromethorphan.
    British journal of clinical pharmacology, 1996, Volume: 42, Issue:5

    Topics: Adult; Antidepressive Agents, Second-Generation; Cytochrome P-450 CYP2D6; Dextromethorphan; Humans; Phenotype; Piperazines; Triazoles

1996

Other Studies

9 other study(ies) available for triazoles and 1-(3-chlorophenyl)piperazine

ArticleYear
Single- and multiple-dose pharmacokinetics of nefazodone in patients with hepatic cirrhosis.
    Clinical pharmacology and therapeutics, 1995, Volume: 58, Issue:4

    Topics: Adult; Antidepressive Agents; Dose-Response Relationship, Drug; Female; Humans; Liver Cirrhosis; Male; Middle Aged; Piperazines; Serotonin Receptor Agonists; Triazoles

1995
Nonlinear pharmacokinetics of nefazodone after escalating single and multiple oral doses.
    Journal of clinical pharmacology, 1995, Volume: 35, Issue:8

    Topics: Adult; Antidepressive Agents; Drug Administration Schedule; Half-Life; Humans; Male; Piperazines; Serotonin Receptor Agonists; Triazoles

1995
Single-dose pharmacokinetics of nefazodone in healthy young and elderly subjects and in subjects with renal or hepatic impairment.
    European journal of clinical pharmacology, 1995, Volume: 49, Issue:3

    Topics: Administration, Oral; Adult; Age Factors; Aged; Antidepressive Agents; Female; Humans; Kidney Diseases; Liver Cirrhosis; Male; Middle Aged; Piperazines; Serotonin Receptor Agonists; Triazoles

1995
Steady-state pharmacokinetics of nefazodone in subjects with normal and impaired renal function.
    European journal of clinical pharmacology, 1995, Volume: 49, Issue:3

    Topics: Antidepressive Agents; Female; Humans; Kidney Diseases; Male; Middle Aged; Piperazines; Serotonin Receptor Agonists; Triazoles

1995
Sensitive liquid chromatographic-mass spectrometric assay for the simultaneous quantitation of nefazodone and its metabolites hydroxynefazodone m-chlorophenylpiperazine and triazole-dione in human plasma using single-ion monitoring.
    Journal of chromatography. B, Biomedical sciences and applications, 1998, Oct-23, Volume: 718, Issue:1

    Topics: Antidepressive Agents, Second-Generation; Chromatography, High Pressure Liquid; Humans; Mass Spectrometry; Piperazines; Reproducibility of Results; Sensitivity and Specificity; Triazoles

1998
Brain-to-blood partition and in vivo inhibition of 5-hydroxytryptamine reuptake and quipazine-mediated behaviour of nefazodone and its main active metabolites in rodents.
    British journal of pharmacology, 1998, Volume: 125, Issue:7

    Topics: Animals; Blood-Brain Barrier; Brain; Cerebral Cortex; Head Movements; Male; Mice; p-Chloroamphetamine; Piperazines; Prodrugs; Quipazine; Rats; Receptor, Serotonin, 5-HT2A; Receptors, Serotonin; Selective Serotonin Reuptake Inhibitors; Serotonin; Serotonin Agents; Serotonin Receptor Agonists; Triazoles

1998
Nefazodone, meta-chlorophenylpiperazine, and their metabolites in vitro: cytochromes mediating transformation, and P450-3A4 inhibitory actions.
    Psychopharmacology, 1999, Volume: 145, Issue:1

    Topics: Alprazolam; Antidepressive Agents; Biotransformation; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Drug Interactions; Humans; Hydroxylation; Microsomes, Liver; Mixed Function Oxygenases; Piperazines; Triazoles

1999
Simultaneous quantitation of d7-nefazodone, nefazodone, d7-hydroxynefazodone, hydroxynefazodone, m-chlorophenylpiperazine and triazole-dione in human plasma by liquid chromatographic-mass spectrometry.
    Biomedical chromatography : BMC, 2000, Volume: 14, Issue:2

    Topics: Chromatography, High Pressure Liquid; Humans; Mass Spectrometry; Piperazines; Reference Standards; Reproducibility of Results; Sensitivity and Specificity; Triazoles

2000
High-throughput quantitation of nefazodone and its metabolites in human plasma by high flow direct-injection LC-MS/MS.
    Journal of pharmaceutical and biomedical analysis, 2007, Apr-11, Volume: 43, Issue:5

    Topics: Antidepressive Agents, Second-Generation; Chromatography, Liquid; Humans; Molecular Structure; Piperazines; Reference Standards; Reproducibility of Results; Sensitivity and Specificity; Spectrometry, Mass, Electrospray Ionization; Tandem Mass Spectrometry; Time Factors; Triazoles

2007