Page last updated: 2024-08-16

triazolam and mibefradil

triazolam has been researched along with mibefradil in 3 studies

Research

Studies (3)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	1 (33.33)	18.2507
2000's	2 (66.67)	29.6817
2010's	0 (0.00)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Topliss, JG; Yoshida, F	1
Lombardo, F; Obach, RS; Waters, NJ	1
Backman, JT; Kivistö, KT; Neuvonen, PJ; Wang, JS; Wen, X	1

Trials

1 trial(s) available for triazolam and mibefradil

Article	Year
Mibefradil but not isradipine substantially elevates the plasma concentrations of the CYP3A4 substrate triazolam. Clinical pharmacology and therapeutics, 1999, Volume: 66, Issue:4 Topics: Administration, Oral; Adult; Anti-Anxiety Agents; Area Under Curve; Calcium Channel Blockers; Cross-Over Studies; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Double-Blind Method; Female; Humans; Isradipine; Male; Mibefradil; Mixed Function Oxygenases; Triazolam	1999

Article

Year

Mibefradil but not isradipine substantially elevates the plasma concentrations of the CYP3A4 substrate triazolam.

Clinical pharmacology and therapeutics, 1999, Volume: 66, Issue:4

Topics: Administration, Oral; Adult; Anti-Anxiety Agents; Area Under Curve; Calcium Channel Blockers; Cross-Over Studies; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Double-Blind Method; Female; Humans; Isradipine; Male; Mibefradil; Mixed Function Oxygenases; Triazolam

1999

Other Studies

2 other study(ies) available for triazolam and mibefradil

Article	Year
QSAR model for drug human oral bioavailability. Journal of medicinal chemistry, 2000, Jun-29, Volume: 43, Issue:13 Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship	2000
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds. Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7 Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding	2008