tretinoin and prolinedithiocarbamate

tretinoin has been researched along with prolinedithiocarbamate* in 1 studies

Other Studies

1 other study(ies) available for tretinoin and prolinedithiocarbamate

Article	Year
Cytokine action and oxidative stress response in differentiated neuroblastoma SH-SY5Y cells. Acta biochimica Polonica, 2003, Volume: 50, Issue:3 In the retinoic acid-differentiated neuroblastoma SH-SY5Y cells, IL-1 induced binding activity of NFkappaB and up-regulated the expression and activity of MnSOD. The IL-1-elicited effects were partly reversed by IL-4 and IL-6. It is proposed that IL-4 and IL-6 may participate in the regulation of the imbalanced oxidant status induced by IL-1 in differentiated neuroblastoma cells. In the SH-SY5Y cell line, TNFalpha neither activated NFkappaB nor induced MnSOD expression and activity, but was capable of modulating the IL-1 effects. Pyrrolidine dithiocarbamate (PDTC), an inhibitor of NFkappaB activation, down-regulated the expression and activity of MnSOD, which may suggest that the regulation of MnSOD by IL-1 in retinoic acid-differentiated neuroblastoma cells was mediated by the nuclear factor kappaB. Topics: Brain Neoplasms; Cell Differentiation; Enzyme Activation; Enzyme Inhibitors; Gene Expression Regulation; Humans; Interleukin-1; Interleukin-4; Interleukin-6; Neuroblastoma; NF-kappa B; Oxidative Stress; Proline; Protein Binding; Superoxide Dismutase; Thiocarbamates; Tretinoin; Tumor Cells, Cultured; Tumor Necrosis Factor-alpha	2003

Article

Year

Cytokine action and oxidative stress response in differentiated neuroblastoma SH-SY5Y cells.

Acta biochimica Polonica, 2003, Volume: 50, Issue:3

In the retinoic acid-differentiated neuroblastoma SH-SY5Y cells, IL-1 induced binding activity of NFkappaB and up-regulated the expression and activity of MnSOD. The IL-1-elicited effects were partly reversed by IL-4 and IL-6. It is proposed that IL-4 and IL-6 may participate in the regulation of the imbalanced oxidant status induced by IL-1 in differentiated neuroblastoma cells. In the SH-SY5Y cell line, TNFalpha neither activated NFkappaB nor induced MnSOD expression and activity, but was capable of modulating the IL-1 effects. Pyrrolidine dithiocarbamate (PDTC), an inhibitor of NFkappaB activation, down-regulated the expression and activity of MnSOD, which may suggest that the regulation of MnSOD by IL-1 in retinoic acid-differentiated neuroblastoma cells was mediated by the nuclear factor kappaB.

Topics: Brain Neoplasms; Cell Differentiation; Enzyme Activation; Enzyme Inhibitors; Gene Expression Regulation; Humans; Interleukin-1; Interleukin-4; Interleukin-6; Neuroblastoma; NF-kappa B; Oxidative Stress; Proline; Protein Binding; Superoxide Dismutase; Thiocarbamates; Tretinoin; Tumor Cells, Cultured; Tumor Necrosis Factor-alpha

2003