tretinoin and ethyl-acetate

tretinoin has been researched along with ethyl-acetate* in 1 studies

Other Studies

1 other study(ies) available for tretinoin and ethyl-acetate

Article	Year
Furocoumarin derivatives from radix Angelicae dahuricae and their effects on RXRα transcriptional regulation. Molecules (Basel, Switzerland), 2011, Jul-26, Volume: 16, Issue:8 A novel furocoumarin derivative named oxyalloimperatorin (1), together with seventeen furocoumarins 2-18 were isolated from the radix of Angelica dahurica. The chemical structure of new metabolite was characterized by analysis of IR, NMR, and HR-ESI-MS spectroscopic data. Among the isolated compounds, 13, 16, and 18 (each at 20 μM) could significantly promote the gene transcriptional function of nuclear receptor RXRα. While 7-9, 13, 14, and the new structure 1 (each at 20 μM) showed significant reduction in RXRα gene transcriptional activities induced by 9-cis-retinoid acid. The findings indicated that these furocoumarin skeleton derivatives might hold beneficial effects on many intractable diseases, such as cancer and metabolic diseases, due to their potential activities on regulating the transcriptional activation function of RXRα. Topics: Acetates; Alitretinoin; Angelica; Diabetes Mellitus; Furocoumarins; Gene Expression; Genes, Reporter; HEK293 Cells; Humans; Luciferases; Magnetic Resonance Spectroscopy; Mass Spectrometry; Neoplasms; Plant Extracts; Plant Roots; Plasmids; Retinoid X Receptor alpha; Transcriptional Activation; Transfection; Tretinoin	2011

Article

Year

Furocoumarin derivatives from radix Angelicae dahuricae and their effects on RXRα transcriptional regulation.

Molecules (Basel, Switzerland), 2011, Jul-26, Volume: 16, Issue:8

A novel furocoumarin derivative named oxyalloimperatorin (1), together with seventeen furocoumarins 2-18 were isolated from the radix of Angelica dahurica. The chemical structure of new metabolite was characterized by analysis of IR, NMR, and HR-ESI-MS spectroscopic data. Among the isolated compounds, 13, 16, and 18 (each at 20 μM) could significantly promote the gene transcriptional function of nuclear receptor RXRα. While 7-9, 13, 14, and the new structure 1 (each at 20 μM) showed significant reduction in RXRα gene transcriptional activities induced by 9-cis-retinoid acid. The findings indicated that these furocoumarin skeleton derivatives might hold beneficial effects on many intractable diseases, such as cancer and metabolic diseases, due to their potential activities on regulating the transcriptional activation function of RXRα.

Topics: Acetates; Alitretinoin; Angelica; Diabetes Mellitus; Furocoumarins; Gene Expression; Genes, Reporter; HEK293 Cells; Humans; Luciferases; Magnetic Resonance Spectroscopy; Mass Spectrometry; Neoplasms; Plant Extracts; Plant Roots; Plasmids; Retinoid X Receptor alpha; Transcriptional Activation; Transfection; Tretinoin

2011