tretinoin and diisononyl-phthalate

tretinoin has been researched along with diisononyl-phthalate* in 1 studies

Other Studies

1 other study(ies) available for tretinoin and diisononyl-phthalate

Article	Year
Effects of Di-isononyl Phthalate on Neuropeptide Y Expression in Differentiating Human Neuronal Cells. Basic & clinical pharmacology & toxicology, 2017, Volume: 120, Issue:3 Neuropeptide Y (NPY) is an abundant neuropeptide in the mammalian brain important for behavioural consequences of stress and energy metabolism. We have addressed possible effects of the phthalate DiNP on NPY expression in human SH-SY5Y cells, a neuronal in vitro differentiation model. Pico- to nanomolar doses of DiNP and its metabolite MiNP resulted in decreased NPY mRNA and peptide expression in retinoid-differentiated cells. Thus, dys-regulated NPY may be an adverse outcome for exposure to low doses of DiNP in human beings. Topics: Cell Differentiation; Cell Line, Tumor; Humans; Neurons; Neuropeptide Y; Phthalic Acids; RNA, Messenger; Tretinoin	2017

Article

Year

Effects of Di-isononyl Phthalate on Neuropeptide Y Expression in Differentiating Human Neuronal Cells.

Basic & clinical pharmacology & toxicology, 2017, Volume: 120, Issue:3

Neuropeptide Y (NPY) is an abundant neuropeptide in the mammalian brain important for behavioural consequences of stress and energy metabolism. We have addressed possible effects of the phthalate DiNP on NPY expression in human SH-SY5Y cells, a neuronal in vitro differentiation model. Pico- to nanomolar doses of DiNP and its metabolite MiNP resulted in decreased NPY mRNA and peptide expression in retinoid-differentiated cells. Thus, dys-regulated NPY may be an adverse outcome for exposure to low doses of DiNP in human beings.

Topics: Cell Differentiation; Cell Line, Tumor; Humans; Neurons; Neuropeptide Y; Phthalic Acids; RNA, Messenger; Tretinoin

2017