tretinoin and butenolide

tretinoin has been researched along with butenolide* in 1 studies

Other Studies

1 other study(ies) available for tretinoin and butenolide

ArticleYear
Biological activities of retinoidal gamma-hydroxybutenolides in cancer cell apoptosis and differentiation.
    Bioorganic & medicinal chemistry, 2005, Nov-01, Volume: 13, Issue:21

    Retinoidal gamma-hydroxybutenolides 2a-d having various lengths of conjugated double bond were prepared in three steps from the corresponding aldehyde 4. Their biological activities were then measured. Of these compounds, only compound 2c possessing a structure similar to that of retinoic acid showed differentiation-inducing activity and very strong apoptosis-inducing activity in HL-60 cells.

    Topics: 4-Butyrolactone; Apoptosis; Cell Differentiation; Gene Expression Regulation, Neoplastic; HL-60 Cells; Humans; Hydrogen; Molecular Structure; Neoplasms; Transcription, Genetic; Tretinoin

2005