tretinoin has been researched along with butenolide* in 1 studies
1 other study(ies) available for tretinoin and butenolide
Article | Year |
---|---|
Biological activities of retinoidal gamma-hydroxybutenolides in cancer cell apoptosis and differentiation.
Retinoidal gamma-hydroxybutenolides 2a-d having various lengths of conjugated double bond were prepared in three steps from the corresponding aldehyde 4. Their biological activities were then measured. Of these compounds, only compound 2c possessing a structure similar to that of retinoic acid showed differentiation-inducing activity and very strong apoptosis-inducing activity in HL-60 cells. Topics: 4-Butyrolactone; Apoptosis; Cell Differentiation; Gene Expression Regulation, Neoplastic; HL-60 Cells; Humans; Hydrogen; Molecular Structure; Neoplasms; Transcription, Genetic; Tretinoin | 2005 |