tretinoin has been researched along with 2-7-fluorenediamine* in 1 studies
1 other study(ies) available for tretinoin and 2-7-fluorenediamine
| Article | Year |
|---|---|
Synthesis of minoxidil conjugates and their evaluation as HL-60 differentiation agents.
Activation of minoxidil (MNX) with N,N'-carbonyldiimidazole and coupling with natural polyamines (PAs) and commercially available aliphatic or aromatic amines provided a series of new conjugates which were evaluated for their ability to induce differentiation to HL-60 acute myeloid leukemia cancer cells, using a modified NBTZ reduction test. Although neither MNX nor 4,4'-methylenedianiline (MDA) or 2,7-diaminofluorene (DAF), alone or in combination, had any effect, the MNX-spermine (SPM) conjugate (11) and the conjugates 7 and 8 of MNX with MDA and DAF exhibited a differentiation-inducing effect at a concentration of 10 μM without being toxic on proliferating human peripheral blood mononuclear cells. Topics: Aniline Compounds; Antineoplastic Agents; Cell Differentiation; Cell Proliferation; Fluorenes; HL-60 Cells; Humans; Imidazoles; Minoxidil; Polyamines; Spermine | 2016 |