Compounds > tretazicar
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tretazicar and pr-104a

tretazicar has been researched along with pr-104a in 3 studies

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's2 (66.67)24.3611
2020's1 (33.33)2.80

Authors

AuthorsStudies
Ay, M; Çelik, A; Gülhan, ÜG; Güngör, T; Hacıoğlu, N; Köçkar, F; Önder, FC; Tok, TT; Tokay, E2
Ackerley, DF; Ashoorzadeh, A; Copp, JN; Denny, WA; Guise, CP; Horvat, CN; Mowday, AM; Patterson, AV; Prosser, GA; Smaill, JB; Swe, PM; Syddall, SP; Williams, EM1

Other Studies

3 other study(ies) available for tretazicar and pr-104a

ArticleYear
PRODRUGS FOR NITROREDUCTASE BASED CANCER THERAPY- 2: Novel amide/Ntr combinations targeting PC3 cancer cells.
    European journal of medicinal chemistry, 2019, Jun-01, Volume: 171

    Topics: Amides; Antineoplastic Agents, Phytogenic; Cell Line, Tumor; Cell Proliferation; Cell Survival; Chromatography, High Pressure Liquid; Dose-Response Relationship, Drug; Drug Discovery; Drug Screening Assays, Antitumor; Humans; Molecular Dynamics Simulation; Molecular Structure; Nitroreductases; PC-3 Cells; Prodrugs; Structure-Activity Relationship

2019
Prodrugs for nitroreductase-based cancer therapy-3: Antitumor activity of the novel dinitroaniline prodrugs/Ssap-NtrB enzyme suicide gene system: Synthesis, in vitro and in silico evaluation in prostate cancer.
    European journal of medicinal chemistry, 2020, Feb-01, Volume: 187

    Topics: Aniline Compounds; Antineoplastic Agents; Cell Proliferation; Cells, Cultured; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; Enzyme Inhibitors; Genetic Therapy; Humans; Male; Models, Molecular; Molecular Structure; Nitroreductases; Prodrugs; Prostatic Neoplasms; Structure-Activity Relationship

2020
Creation and screening of a multi-family bacterial oxidoreductase library to discover novel nitroreductases that efficiently activate the bioreductive prodrugs CB1954 and PR-104A.
    Biochemical pharmacology, 2013, Apr-15, Volume: 85, Issue:8

    Topics: Antineoplastic Agents; Aziridines; Escherichia coli; Gene Library; Genetic Therapy; HCT116 Cells; Humans; Nitrogen Mustard Compounds; Nitroreductases; Prodrugs; SOS Response, Genetics

2013