Page last updated: 2024-08-26

tretazicar and n-((n,n-dimethylamino)ethyl)-5-(n,n-bis(2-chloroethyl)amino)-2,4-dinitrobenzamide

tretazicar has been researched along with n-((n,n-dimethylamino)ethyl)-5-(n,n-bis(2-chloroethyl)amino)-2,4-dinitrobenzamide in 3 studies

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's2 (66.67)18.2507
2000's1 (33.33)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Cliffe, S; Denny, WA; Palmer, BD; Wilson, WR1
Atwell, GJ; Denny, WA; Palmer, BD; Schultz, D; Wilson, WR; Xu, XZ1
Atwell, GJ; Denny, WA; Hogg, A; Patterson, AV; Pruijn, FB; Pullen, SM; Wilson, WR; Yang, S1

Other Studies

3 other study(ies) available for tretazicar and n-((n,n-dimethylamino)ethyl)-5-(n,n-bis(2-chloroethyl)amino)-2,4-dinitrobenzamide

ArticleYear
Hypoxia-selective antitumor agents. 5. Synthesis of water-soluble nitroaniline mustards with selective cytotoxicity for hypoxic mammalian cells.
    Journal of medicinal chemistry, 1992, Aug-21, Volume: 35, Issue:17

    Topics: Aniline Compounds; Aniline Mustard; Animals; Antineoplastic Agents; Cell Survival; Chemical Phenomena; Chemistry, Physical; CHO Cells; Cricetinae; Humans; Molecular Structure; Mustard Compounds; NAD(P)H Dehydrogenase (Quinone); Oxidation-Reduction; Oxygen; Rats; Solubility; Structure-Activity Relationship; Tumor Cells, Cultured; Water

1992
Hypoxia-selective antitumor agents. 9. Structure-activity relationships for hypoxia-selective cytotoxicity among analogues of 5-[N,N-bis(2-chloroethyl)amino]-2,4-dinitrobenzamide.
    Journal of medicinal chemistry, 1994, Jul-08, Volume: 37, Issue:14

    Topics: Aniline Mustard; Animals; Antineoplastic Agents; Cell Hypoxia; CHO Cells; Cricetinae; NAD(P)H Dehydrogenase (Quinone); Rats; Structure-Activity Relationship

1994
Synthesis and structure-activity relationships for 2,4-dinitrobenzamide-5-mustards as prodrugs for the Escherichia coli nfsB nitroreductase in gene therapy.
    Journal of medicinal chemistry, 2007, Mar-22, Volume: 50, Issue:6

    Topics: Animals; Antineoplastic Agents, Alkylating; Bystander Effect; Cell Line, Tumor; Drug Screening Assays, Antitumor; Enzyme Activation; Escherichia coli Proteins; Female; Genetic Therapy; Humans; Least-Squares Analysis; Male; Mice; Mice, Nude; Multivariate Analysis; Nitrogen Mustard Compounds; Nitroreductases; Prodrugs; Quantitative Structure-Activity Relationship; Transplantation, Heterologous

2007