Compounds > tretazicar
Page last updated: 2024-08-26

tretazicar and dicumarol

tretazicar has been researched along with dicumarol in 4 studies

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19901 (25.00)18.7374
1990's1 (25.00)18.2507
2000's2 (50.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Boland, MP; Friedlos, F; Knox, RJ; Kotsaki-Kovatsi, VP; Marchbank, T; Roberts, JJ1
Cenas, N; Dickancaite, E; Miskiniene, V; Nemeikaite, A1
Denny, WA; Johansson, E; Neidle, S; Parkinson, GN1
Helsby, NA; Tang, MH; Tingle, MD; Wilson, WR1

Other Studies

4 other study(ies) available for tretazicar and dicumarol

ArticleYear
Caffeine, aminoimidazolecarboxamide and dicoumarol, inhibitors of NAD(P)H dehydrogenase (quinone) (DT diaphorase), prevent both the cytotoxicity and DNA interstrand crosslinking produced by 5-(aziridin-1-yl)-2,4-dinitrobenzamide (CB 1954) in Walker cells.
    Biochemical pharmacology, 1989, Nov-15, Volume: 38, Issue:22

    Topics: Aminoimidazole Carboxamide; Animals; Antineoplastic Agents; Aziridines; Caffeine; Cross-Linking Reagents; Dicumarol; DNA; Drug Synergism; NAD(P)H Dehydrogenase (Quinone); Neoplasms, Experimental; Quinone Reductases; Rats; Tumor Cells, Cultured; Vitamin K

1989
Nitroaromatic betulin derivatives as redox cycling agents.
    Biochemistry and molecular biology international, 1997, Volume: 42, Issue:2

    Topics: Animals; Aziridines; Dicumarol; Dose-Response Relationship, Drug; Ferredoxin-NADP Reductase; Fibroblasts; Furans; Kidney; L-Lactate Dehydrogenase; L-Lactate Dehydrogenase (Cytochrome); Leukemia Virus, Bovine; NAD(P)H Dehydrogenase (Quinone); Nitro Compounds; Nitrobenzoates; Nitrofurantoin; Oxidation-Reduction; Oxidative Stress; Substrate Specificity; Toxicity Tests; Triterpenes

1997
Studies on the nitroreductase prodrug-activating system. Crystal structures of complexes with the inhibitor dicoumarol and dinitrobenzamide prodrugs and of the enzyme active form.
    Journal of medicinal chemistry, 2003, Sep-11, Volume: 46, Issue:19

    Topics: Aniline Mustard; Aziridines; Benzamides; Binding Sites; Crystallography, X-Ray; Dicumarol; Drug Design; Enzyme Activation; Enzyme Inhibitors; Escherichia coli; Flavin Mononucleotide; Models, Molecular; Nitroreductases; Oxidation-Reduction; Prodrugs; Protein Binding

2003
Aerobic 2- and 4-nitroreduction of CB 1954 by human liver.
    Toxicology, 2005, Dec-15, Volume: 216, Issue:2-3

    Topics: Antineoplastic Agents; Aziridines; Carbon Monoxide; Chromatography, High Pressure Liquid; Clinical Trials, Phase I as Topic; Cytosol; Cytotoxins; Dicumarol; Escherichia coli; Humans; Hydroxylamines; Hypoxia; Liver; Mass Spectrometry; Microsomes, Liver; NAD; NADP; Nitroreductases; Prodrugs

2005