Compounds > tretazicar
Page last updated: 2024-08-26

tretazicar and aniline mustard

tretazicar has been researched along with aniline mustard in 8 studies

Research

Studies (8)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (12.50)18.2507
2000's5 (62.50)29.6817
2010's2 (25.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Anlezark, GM; Denny, WA; Friedlos, F; Knox, RJ; Melton, RG; Palmer, BD; Sherwood, RF; Williams, A; Wilson, WR1
Kestell, P; Palmer, BD; Pruijn, FB; Siim, BG; Wilson, WR1
Denny, WA; Helsby, NA; Hicks, KO; Hogg, A; Pullen, SM; Wilson, WR1
Denny, WA; Helsby, NA; Palmer, BD; Pruijn, FB; Wheeler, SJ; Wilson, WR; Yang, S1
Denny, WA; Johansson, E; Neidle, S; Parkinson, GN1
Ferry, DM; Helsby, NA; Patterson, AV; Pullen, SM; Wilson, WR1
Çelik, A; Yetiş, G1
Ay, M; Celik, A; Gungor, T; Kockar, F; Onder, FC; Tok, TT; Tokay, E; Yetis, G1

Other Studies

8 other study(ies) available for tretazicar and aniline mustard

ArticleYear
Bioactivation of dinitrobenzamide mustards by an E. coli B nitroreductase.
    Biochemical pharmacology, 1995, Aug-25, Volume: 50, Issue:5

    Topics: Aniline Mustard; Animals; Antineoplastic Agents; Aziridines; Biotransformation; Cell Line; Cricetinae; Escherichia coli; Kinetics; Nitroreductases; Oxidation-Reduction; Prodrugs; Substrate Specificity

1995
Pharmacokinetics and metabolism of the nitrogen mustard bioreductive drug 5.
    Cancer chemotherapy and pharmacology, 2000, Volume: 46, Issue:5

    Topics: Aniline Mustard; Animals; Antineoplastic Agents; Aziridines; Biotransformation; Chromatography, High Pressure Liquid; Injections, Intravenous; Injections, Subcutaneous; Male; Mice; Mice, Inbred C3H; Neoplasms, Experimental; Prodrugs

2000
Quantitation of bystander effects in nitroreductase suicide gene therapy using three-dimensional cell cultures.
    Cancer research, 2002, Mar-01, Volume: 62, Issue:5

    Topics: Aniline Mustard; Animals; Aziridines; Bystander Effect; Cell Culture Techniques; Cricetinae; Genetic Therapy; Humans; Neoplasms; Nitroreductases; Prodrugs; Structure-Activity Relationship; Tumor Cells, Cultured

2002
Effect of nitroreduction on the alkylating reactivity and cytotoxicity of the 2,4-dinitrobenzamide-5-aziridine CB 1954 and the corresponding nitrogen mustard SN 23862: distinct mechanisms of bioreductive activation.
    Chemical research in toxicology, 2003, Volume: 16, Issue:4

    Topics: Aniline Mustard; Animals; Antineoplastic Agents, Alkylating; Aziridines; Chromatography, High Pressure Liquid; Cricetinae; Electrochemistry; Hydrolysis; Kinetics; Mass Spectrometry; Nitroreductases; Prodrugs; Time Factors; Tumor Cells, Cultured

2003
Studies on the nitroreductase prodrug-activating system. Crystal structures of complexes with the inhibitor dicoumarol and dinitrobenzamide prodrugs and of the enzyme active form.
    Journal of medicinal chemistry, 2003, Sep-11, Volume: 46, Issue:19

    Topics: Aniline Mustard; Aziridines; Benzamides; Binding Sites; Crystallography, X-Ray; Dicumarol; Drug Design; Enzyme Activation; Enzyme Inhibitors; Escherichia coli; Flavin Mononucleotide; Models, Molecular; Nitroreductases; Oxidation-Reduction; Prodrugs; Protein Binding

2003
2-Amino metabolites are key mediators of CB 1954 and SN 23862 bystander effects in nitroreductase GDEPT.
    British journal of cancer, 2004, Mar-08, Volume: 90, Issue:5

    Topics: Aniline Mustard; Antineoplastic Agents; Aziridines; Bystander Effect; Chromatography, High Pressure Liquid; Escherichia coli; Genetic Therapy; Genetic Vectors; Humans; Mass Spectrometry; Neoplasms; Nitroreductases; Prodrugs; Structure-Activity Relationship; Tumor Cells, Cultured

2004
An unusually cold active nitroreductase for prodrug activations.
    Bioorganic & medicinal chemistry, 2012, Jun-01, Volume: 20, Issue:11

    Topics: Aniline Mustard; Aziridines; Cloning, Molecular; Electrophoresis, Polyacrylamide Gel; Enzyme Stability; Escherichia coli; Flavin Mononucleotide; Hydrogen-Ion Concentration; Mass Spectrometry; Nitrofurazone; Nitroreductases; Phylogeny; Prodrugs; Recombinant Proteins; Staphylococcus saprophyticus; Temperature

2012
Prodrugs for Nitroreductase Based Cancer Therapy- 1: Metabolite Profile, Cell Cytotoxicity and Molecular Modeling Interactions of Nitro Benzamides with Ssap-NtrB.
    Medicinal chemistry (Shariqah (United Arab Emirates)), 2018, Volume: 14, Issue:5

    Topics: Aniline Mustard; Antineoplastic Agents; Aziridines; Benzamides; Cell Line, Tumor; Human Umbilical Vein Endothelial Cells; Humans; Kinetics; Molecular Docking Simulation; Nitrobenzenes; Nitroreductases; Prodrugs; Staphylococcus saprophyticus

2018