Page last updated: 2024-08-18

trehalose and muramidase

trehalose has been researched along with muramidase in 65 studies

Research

Studies (65)

TimeframeStudies, this research(%)All Research%
pre-19901 (1.54)18.7374
1990's3 (4.62)18.2507
2000's19 (29.23)29.6817
2010's38 (58.46)24.3611
2020's4 (6.15)2.80

Authors

AuthorsStudies
Carpenter, JF; Crowe, JH1
Emoto, Y; Katsuzaki, T; Maeda, K; Miyazaki, T; Niwa, T; Tatemichi, N; Yazawa, T1
Fu, K; Griebenow, K; Hsieh, L; Klibanov, AM1
Allison, SD; Carpenter, JF; Chang, B; Randolph, TW1
Imoto, T; Nagata, M; Ueda, T1
Bustami, R; Chan, HK; Lam, YH; Phan, T; Separovic, F1
Sankaranarayanan, R; Saraswathi, NT; Vijayan, M1
Brown, MB; Liao, YH; Martin, GP; Nazir, T; Quader, A1
Bhat, R; Kaushik, JK1
Brown, MB; Liao, YH; Martin, GP; Quader, A1
Hünenberger, PH; Lins, RD; Pereira, CS1
Azzam, S; Caliskan, G; Cicerone, MT; Kisliuk, A; Lin-Gibson, S; Mechtani, D; Peral, I; Roh, JH; Sokolov, AP1
Bouchard, A; Crommelin, DJ; Hofland, GW; Jiskoot, W; Jovanović, N; Witkamp, GJ1
Carri, GA; Curtis, JE; Dirama, TE; Sokolov, AP1
Cordone, L; Cottone, G; Giuffrida, S1
Bouchard, A; Gerich, A; Jiskoot, W; Jovanović, N1
Engstrom, JD; Johnston, KP; Lai, ES; Simpson, DT; Williams, RO1
Affouard, F; Descamps, M; Guinet, Y; Hédoux, A; Ionov, R; Lerbret, A; Paccou, L; Willart, JF1
Affouard, F; Bordat, P; Descamps, M; Guinet, Y; Hédoux, A; Lerbret, A1
Magazù, S; Romeo, G; Telling, MT1
Bouchard, A; Crommelin, DJ; Hofland, GW; Jiskoot, W; Jovanović, N; Sutter, M; Van Speybroeck, M; Witkamp, GJ1
Bonner, MC; Forbes, RT; Getrost, M; Hulse, WL1
Aksan, A; Bischof, JC; Dong, J; Hubel, A1
Padilla, AM; Pikal, MJ1
Fedorov, MV; Goodman, JM; Nerukh, D; Schumm, S1
Corrigan, OI; Healy, AM; Li, J; Ogáin, ON; Tajber, L1
Erdinc, B; Neufeld, RJ1
Bellavia, G; Cordone, L; Cottone, G; Cupane, A; Giuffrida, S1
Aso, Y; Forney, KM; Pikal, MJ; Yoshioka, S1
Lee, J; Mancini, RJ; Maynard, HD1
Caccamo, MT; Magazù, S; Migliardo, F1
Affouard, F; Bellissent-Funel, MC; Descamps, M; Hédoux, A; Krenzlin, S; Lerbret, A; Siepmann, J1
James, S; McManus, JJ1
Desai, KG; Olsen, KF; Reinhold, SE; Schwendeman, SP; Zhang, L1
Barreca, D; Bellocco, E; Ficarra, S; Gattuso, G; La Torre, R; Laganà, G; Magazù, S; Tellone, E1
Corradini, D; Gallo, P; Stanley, HE; Strekalova, EG1
Carri, GA; GhattyVenkataKrishna, PK1
Achir, S; Guinet, Y; Hedoux, A; Paccou, L1
Blumlein, A; McManus, JJ1
Barreca, D; Bellocco, E; Gattuso, G; Laganà, G; Magazù, S; Migliardo, F1
Avanti, C; Frijlink, HW; Hinrichs, WL; Saluja, V; van Streun, EL1
Ketolainen, J; Molnár, F; Peters, BH1
Guinet, Y; Hédoux, A; Paccou, L1
Bellavia, G; Guinet, Y; Hédoux, A; Paccou, L1
Deep, S; Katyal, N1
Diallo, SO; Mamontov, E; O'Neill, H; Zhang, Q1
Francia, F; Malferrari, M; Venturoli, G1
Barman, I; Narayana, C; Siddhanta, S1
Capaccioli, S; Ngai, KL; Paciaroni, A1
Falus, P; Farago, B; Magazù, S; Mamontov, E; Mezei, F; Migliardo, F; Russina, M1
Khan, FI; Qi, S; Wang, Y; Xin, R; Yang, B; Zeng, C1
Gröger, S; Hackel, C; Reichert, D1
Chatterjee, R; Kolli, V; Sarkar, N1
Guinet, Y; Hedoux, A; Paccou, L; Starciuc, T1
Affouard, F; Lerbret, A1
Ali, MM; Brennan, JD; Brown, CL; Filipe, CDM; Jahanshahi-Anbuhi, S; Kannan, B; Li, Y1
Hansen, SH; Ji, S; Mu, H; Rantanen, J; Thulstrup, PW; van de Weert, M; Yang, M1
Bosquillon, C; Childerhouse, N; Coghlan, D; Falcone, FH; Mantovani, G; Nieto-Orellana, A; Rothery, M; Stolnik, S1
Koranne, S; Suryanarayanan, R; Thakral, S1
Frijlink, HW; Hinrichs, WLJ; Klever, JS; Tian, Y; Visser, JC; Woerdenbag, HJ1
Comez, L; Corezzi, S; Fioretto, D; Morresi, A; Paolantoni, M; Sassi, P1
Correia, NT; Danede, F; Guinet, Y; Hedoux, A; Malfait, B; Paccou, L; Starciuc, T1
Camisasca, G; De Marzio, M; Gallo, P1
Cristiglio, V; Shalaev, E; Sztucki, M; Wu, C1
Hamawandi, B; Lajmorak, A; Lalegani, Z; Seyyed Ebrahimi, SA; Yazdian, F1

Other Studies

65 other study(ies) available for trehalose and muramidase

ArticleYear
An infrared spectroscopic study of the interactions of carbohydrates with dried proteins.
    Biochemistry, 1989, May-02, Volume: 28, Issue:9

    Topics: Carbohydrates; Drug Stability; Freeze Drying; Inositol; Lactose; Muramidase; Phosphofructokinase-1; Serum Albumin, Bovine; Spectrophotometry, Infrared; Trehalose

1989
Urinary trehalase activity in chronic glomerulonephritis.
    Nephron, 1993, Volume: 63, Issue:4

    Topics: Acetylglucosaminidase; Adolescent; Adult; Aged; Aged, 80 and over; Aminopeptidases; beta 2-Microglobulin; Biomarkers; Carbohydrate Sequence; CD13 Antigens; Chronic Disease; Female; Glomerulonephritis; Humans; Male; Middle Aged; Molecular Sequence Data; Muramidase; Trehalase; Trehalose

1993
FTIR characterization of the secondary structure of proteins encapsulated within PLGA microspheres.
    Journal of controlled release : official journal of the Controlled Release Society, 1999, Apr-19, Volume: 58, Issue:3

    Topics: Animals; Cattle; Chickens; Drug Stability; Egg White; Excipients; In Vitro Techniques; Lactic Acid; Microspheres; Muramidase; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Polymers; Protein Structure, Secondary; Serum Albumin, Bovine; Spectroscopy, Fourier Transform Infrared; Trehalose

1999
Hydrogen bonding between sugar and protein is responsible for inhibition of dehydration-induced protein unfolding.
    Archives of biochemistry and biophysics, 1999, May-15, Volume: 365, Issue:2

    Topics: Animals; Binding Sites; Chickens; Deuterium Oxide; Freeze Drying; Hydrogen Bonding; Muramidase; Protein Denaturation; Protein Folding; Spectrophotometry, Infrared; Sucrose; Trehalose

1999
Aggregation and chemical reaction in hen lysozyme caused by heating at pH 6 are depressed by osmolytes, sucrose and trehalose.
    Journal of biochemistry, 2001, Volume: 130, Issue:4

    Topics: Alkylation; Animals; Circular Dichroism; Enzyme Stability; Hot Temperature; Hydrogen-Ion Concentration; Kinetics; Muramidase; Osmotic Pressure; Protein Denaturation; Protein Folding; Protein Structure, Secondary; Protein Structure, Tertiary; Spectrometry, Fluorescence; Sucrose; Trehalose; Tryptophan

2001
A solid-state NMR study of protein mobility in lyophilized protein-sugar powders.
    Journal of pharmaceutical sciences, 2002, Volume: 91, Issue:4

    Topics: Carbohydrates; Drug Stability; Enzyme Activation; Enzyme Stability; Freeze Drying; Humidity; Lactose; Muramidase; Nuclear Magnetic Resonance, Biomolecular; Powders; Proteins; Trehalose

2002
Effect of stabilizing additives on the structure and hydration of proteins: a study involving monoclinic lysozyme.
    Acta crystallographica. Section D, Biological crystallography, 2002, Volume: 58, Issue:Pt 7

    Topics: Animals; Chickens; Crystallography, X-Ray; Glycerol; Muramidase; Proteins; Sodium Chloride; Sorbitol; Sucrose; Temperature; Trehalose; Water

2002
Effects of sucrose and trehalose on the preservation of the native structure of spray-dried lysozyme.
    Pharmaceutical research, 2002, Volume: 19, Issue:12

    Topics: Chemistry, Pharmaceutical; Enzyme Stability; Muramidase; Sucrose; Trehalose

2002
Why is trehalose an exceptional protein stabilizer? An analysis of the thermal stability of proteins in the presence of the compatible osmolyte trehalose.
    The Journal of biological chemistry, 2003, Jul-18, Volume: 278, Issue:29

    Topics: alpha-Amylases; Animals; Cattle; Chemical Phenomena; Chemistry, Physical; Chymotrypsinogen; Cytochrome c Group; Drug Stability; Enzyme Stability; Excipients; In Vitro Techniques; Kinetics; Muramidase; Plant Proteins; Protein Denaturation; Proteins; Ribonuclease, Pancreatic; Solutions; Surface Tension; Temperature; Thermodynamics; Trehalose; Trypsin Inhibitors

2003
Investigation of the physical properties of spray-dried stabilised lysozyme particles.
    The Journal of pharmacy and pharmacology, 2003, Volume: 55, Issue:9

    Topics: Crystallization; Desiccation; Drug Stability; Excipients; Microscopy, Electron, Scanning; Muramidase; Nebulizers and Vaporizers; Particle Size; Powders; Sucrose; Technology, Pharmaceutical; Transition Temperature; Trehalose

2003
Trehalose-protein interaction in aqueous solution.
    Proteins, 2004, Apr-01, Volume: 55, Issue:1

    Topics: Computer Simulation; Hydrogen Bonding; Models, Molecular; Muramidase; Proteins; Trehalose; Water

2004
Protein and solvent dynamics: how strongly are they coupled?
    The Journal of chemical physics, 2004, Jul-22, Volume: 121, Issue:4

    Topics: Glycerol; Muramidase; Neutrons; Protein Conformation; Scattering, Radiation; Spectrum Analysis, Raman; Thermodynamics; Trehalose

2004
Distinct effects of sucrose and trehalose on protein stability during supercritical fluid drying and freeze-drying.
    European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences, 2006, Volume: 27, Issue:4

    Topics: Animals; Carbon Dioxide; Chemistry, Pharmaceutical; Desiccation; Ethanol; Excipients; Freeze Drying; Muramidase; Myoglobin; Proteins; Solutions; Sucrose; Temperature; Trehalose

2006
Coupling between lysozyme and trehalose dynamics: microscopic insights from molecular-dynamics simulations.
    The Journal of chemical physics, 2006, Jan-21, Volume: 124, Issue:3

    Topics: Computer Simulation; Hydrogen Bonding; Models, Theoretical; Muramidase; Protein Binding; Protein Conformation; Temperature; Trehalose

2006
Role of solvent on protein-matrix coupling in MbCO embedded in water-saccharide systems: a Fourier transform infrared spectroscopy study.
    Biophysical journal, 2006, Aug-01, Volume: 91, Issue:3

    Topics: Carbohydrate Conformation; Glucose; Hot Temperature; Lactose; Maltose; Muramidase; Myoglobin; Polysaccharides; Protein Conformation; Raffinose; Solvents; Spectroscopy, Fourier Transform Infrared; Trehalose; Water

2006
Near-infrared imaging for studying homogeneity of protein-sugar mixtures.
    Pharmaceutical research, 2006, Volume: 23, Issue:9

    Topics: Algorithms; Carbohydrates; Chromatography, Supercritical Fluid; Data Interpretation, Statistical; Diagnostic Imaging; Freeze Drying; Muramidase; Principal Component Analysis; Proteins; Spectroscopy, Near-Infrared; Trehalose

2006
Morphology of protein particles produced by spray freezing of concentrated solutions.
    European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V, 2007, Volume: 65, Issue:2

    Topics: Algorithms; Freezing; Humidity; Microscopy, Electron, Scanning; Muramidase; Nitrogen; Particle Size; Pentanes; Powders; Proteins; Solutions; Trehalose; Viscosity

2007
Analysis of sugar bioprotective mechanisms on the thermal denaturation of lysozyme from Raman scattering and differential scanning calorimetry investigations.
    The journal of physical chemistry. B, 2006, Nov-16, Volume: 110, Issue:45

    Topics: Amides; Calorimetry, Differential Scanning; Carbohydrates; Enzyme Stability; Hydrogen Bonding; Hydrophobic and Hydrophilic Interactions; Muramidase; Protein Denaturation; Solvents; Spectrum Analysis, Raman; Temperature; Trehalose; Water

2006
How do trehalose, maltose, and sucrose influence some structural and dynamical properties of lysozyme? Insight from molecular dynamics simulations.
    The journal of physical chemistry. B, 2007, Aug-09, Volume: 111, Issue:31

    Topics: Animals; Chickens; Computer Simulation; Maltose; Models, Molecular; Muramidase; Probability; Protein Conformation; Solvents; Sucrose; Trehalose; Water

2007
Temperature dependence of protein dynamics as affected by sugars: a neutron scattering study.
    European biophysics journal : EBJ, 2007, Volume: 36, Issue:7

    Topics: Muramidase; Neutron Diffraction; Protein Conformation; Scattering, Radiation; Sucrose; Temperature; Trehalose; Water

2007
Stable sugar-based protein formulations by supercritical fluid drying.
    International journal of pharmaceutics, 2008, Jan-04, Volume: 346, Issue:1-2

    Topics: Calorimetry, Differential Scanning; Carbon Dioxide; Crystallization; Desiccation; Drug Compounding; Drug Stability; Drug Storage; Ethanol; Microscopy, Electron, Scanning; Muramidase; Particle Size; Powders; Spectroscopy, Fourier Transform Infrared; Sucrose; Trehalose; Water; X-Ray Diffraction

2008
Do co-spray dried excipients offer better lysozyme stabilisation than single excipients?
    European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences, 2008, Mar-03, Volume: 33, Issue:3

    Topics: Calorimetry, Differential Scanning; Drug Compounding; Drug Stability; Excipients; Mannitol; Micrococcus; Muramidase; Sorbitol; Thermogravimetry; Trehalose; X-Ray Diffraction

2008
Freezing-induced phase separation and spatial microheterogeneity in protein solutions.
    The journal of physical chemistry. B, 2009, Jul-30, Volume: 113, Issue:30

    Topics: Animals; Cryoprotective Agents; Dose-Response Relationship, Drug; Freezing; Muramidase; Protein Binding; Protein Structure, Secondary; Proteins; Solutions; Thermodynamics; Trehalose

2009
The study of phase separation in amorphous freeze-dried systems, part 2: investigation of Raman mapping as a tool for studying amorphous phase separation in freeze-dried protein formulations.
    Journal of pharmaceutical sciences, 2011, Volume: 100, Issue:4

    Topics: Animals; Calorimetry, Differential Scanning; Cattle; Chickens; Excipients; Ficoll; Freeze Drying; Microscopy; Muramidase; Phase Transition; Serum Albumin, Bovine; Spectrum Analysis, Raman; Trehalose

2011
Self-assembly of trehalose molecules on a lysozyme surface: the broken glass hypothesis.
    Physical chemistry chemical physics : PCCP, 2011, Feb-14, Volume: 13, Issue:6

    Topics: Anti-Infective Agents; Computer Simulation; Hydrogen Bonding; Models, Molecular; Muramidase; Protein Conformation; Trehalose; Water

2011
Particle engineering of materials for oral inhalation by dry powder inhalers. I-Particles of sugar excipients (trehalose and raffinose) for protein delivery.
    International journal of pharmaceutics, 2011, Feb-28, Volume: 405, Issue:1-2

    Topics: Administration, Inhalation; Chemical Phenomena; Drug Compounding; Drug Stability; Dry Powder Inhalers; Excipients; Muramidase; Particle Size; Powders; Raffinose; Trehalose

2011
Protein micro and nanoencapsulation within glycol-chitosan/Ca²+/alginate matrix by spray drying.
    Drug development and industrial pharmacy, 2011, Volume: 37, Issue:6

    Topics: Alginates; Calcium; Chitosan; Drug Carriers; Excipients; Glucuronic Acid; Hexuronic Acids; Microspheres; Muramidase; Nanoparticles; Particle Size; Protein Stability; Serum Albumin, Bovine; Subtilisin; Temperature; Trehalose

2011
Protein thermal denaturation and matrix glass transition in different protein-trehalose-water systems.
    The journal of physical chemistry. B, 2011, May-19, Volume: 115, Issue:19

    Topics: Animals; Calorimetry, Differential Scanning; Cattle; Hemoglobins; Molecular Dynamics Simulation; Muramidase; Myoglobin; Phase Transition; Protein Denaturation; Proteins; Serum Albumin, Bovine; Temperature; Trehalose; Water

2011
Effect of sugars on the molecular motion of freeze-dried protein formulations reflected by NMR relaxation times.
    Pharmaceutical research, 2011, Volume: 28, Issue:12

    Topics: Freeze Drying; Isomaltose; Magnetic Resonance Spectroscopy; Motion; Muramidase; Sucrose; Temperature; Trehalose

2011
Trehalose glycopolymers for stabilization of protein conjugates to environmental stressors.
    Journal of the American Chemical Society, 2012, May-23, Volume: 134, Issue:20

    Topics: Animals; Chickens; Freeze Drying; Hot Temperature; Models, Molecular; Muramidase; Polymerization; Polymers; Protein Stability; Trehalose

2012
Innovative wavelet protocols in analyzing elastic incoherent neutron scattering.
    The journal of physical chemistry. B, 2012, Aug-09, Volume: 116, Issue:31

    Topics: Maltose; Muramidase; Neutron Diffraction; Neutrons; Sucrose; Temperature; Trehalose; Water

2012
How strongly does trehalose interact with lysozyme in the solid state? Insights from molecular dynamics simulation and inelastic neutron scattering.
    The journal of physical chemistry. B, 2012, Sep-13, Volume: 116, Issue:36

    Topics: Animals; Chickens; Enzyme Stability; Excipients; Freeze Drying; Hydrogen Bonding; Molecular Dynamics Simulation; Muramidase; Trehalose

2012
Thermal and solution stability of lysozyme in the presence of sucrose, glucose, and trehalose.
    The journal of physical chemistry. B, 2012, Aug-30, Volume: 116, Issue:34

    Topics: Enzyme Stability; Glucose; Hydrogen-Ion Concentration; Muramidase; Solutions; Sucrose; Temperature; Trehalose

2012
Self-healing microencapsulation of biomacromolecules without organic solvents.
    Angewandte Chemie (International ed. in English), 2012, Oct-22, Volume: 51, Issue:43

    Topics: Animals; Cattle; Coumarins; Drug Compounding; Kinetics; Lactic Acid; Macromolecular Substances; Muramidase; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Serum Albumin, Bovine; Solvents; Temperature; Trehalose

2012
Spectroscopic determination of lysozyme conformational changes in the presence of trehalose and guanidine.
    Cell biochemistry and biophysics, 2013, Volume: 66, Issue:2

    Topics: Animals; Chickens; Circular Dichroism; Deuterium Exchange Measurement; Guanidine; Kinetics; Magnetic Resonance Spectroscopy; Muramidase; Ovum; Protein Refolding; Protein Structure, Tertiary; Solvents; Spectrometry, Mass, Electrospray Ionization; Thermodynamics; Trehalose

2013
Microscopic mechanism of protein cryopreservation in an aqueous solution with trehalose.
    Scientific reports, 2013, Volume: 3

    Topics: Cryopreservation; Molecular Dynamics Simulation; Muramidase; Temperature; Trehalose; Water

2013
The effect of complex solvents on the structure and dynamics of protein solutions: The case of Lysozyme in trehalose/water mixtures.
    The European physical journal. E, Soft matter, 2013, Volume: 36, Issue:2

    Topics: Animals; Hydrogen Bonding; Muramidase; Protein Structure, Tertiary; Solutions; Solvents; Trehalose; Water

2013
Mechanism of protein stabilization by trehalose during freeze-drying analyzed by in situ micro-raman spectroscopy.
    Journal of pharmaceutical sciences, 2013, Volume: 102, Issue:8

    Topics: Chymotrypsinogen; Freeze Drying; Muramidase; Protein Conformation; Protein Stability; Spectrum Analysis, Raman; Trehalose

2013
Reversible and non-reversible thermal denaturation of lysozyme with varying pH at low ionic strength.
    Biochimica et biophysica acta, 2013, Volume: 1834, Issue:10

    Topics: Animals; Calorimetry, Differential Scanning; Chickens; Electrophoresis, Polyacrylamide Gel; Hot Temperature; Hydrogen-Ion Concentration; Kinetics; Maltose; Muramidase; Osmolar Concentration; Protein Denaturation; Protein Folding; Solutions; Thermodynamics; Trehalose

2013
FTIR, ESI-MS, VT-NMR and SANS study of trehalose thermal stabilization of lysozyme.
    International journal of biological macromolecules, 2014, Volume: 63

    Topics: Animals; Chickens; Magnetic Resonance Spectroscopy; Micrococcus; Muramidase; Protein Stability; Protein Structure, Secondary; Spectrometry, Mass, Electrospray Ionization; Spectroscopy, Fourier Transform Infrared; Temperature; Trehalose

2014
Stability of lysozyme in aqueous extremolyte solutions during heat shock and accelerated thermal conditions.
    PloS one, 2014, Volume: 9, Issue:1

    Topics: Amino Acids, Diamino; Betaine; Enzyme Stability; Glyceric Acids; Hot Temperature; Mannose; Muramidase; Protein Unfolding; Solutions; Trehalose

2014
Structural attributes of model protein formulations prepared by rapid freeze-drying cycles in a microscale heating stage.
    European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V, 2014, Volume: 87, Issue:2

    Topics: Animals; Chemistry, Pharmaceutical; Chickens; Equipment Design; Freeze Drying; Mannitol; Microscopy, Electron, Scanning; Miniaturization; Muramidase; Porosity; Protein Conformation; Sucrose; Surface Properties; Technology, Pharmaceutical; Time Factors; Trehalose; Water; X-Ray Microtomography

2014
Relationship between β-relaxation and structural stability of lysozyme: microscopic insight on thermostabilization mechanism by trehalose from Raman spectroscopy experiments.
    The Journal of chemical physics, 2014, Jun-14, Volume: 140, Issue:22

    Topics: Amides; Muramidase; Protein Conformation; Protein Stability; Solvents; Spectrum Analysis, Raman; Temperature; Trehalose; Water

2014
How does glycerol enhance the bioprotective properties of trehalose? Insight from protein-solvent dynamics.
    The journal of physical chemistry. B, 2014, Jul-31, Volume: 118, Issue:30

    Topics: Animals; Chickens; Glycerol; Linear Models; Muramidase; Phospholipids; Protein Stability; Protein Unfolding; Solvents; Spectrum Analysis, Raman; Temperature; Trehalose; Water

2014
Revisiting the conundrum of trehalose stabilization.
    Physical chemistry chemical physics : PCCP, 2014, Dec-28, Volume: 16, Issue:48

    Topics: Animals; Chickens; Excipients; Models, Molecular; Muramidase; Protein Binding; Protein Denaturation; Protein Stability; Static Electricity; Thermodynamics; Trehalose

2014
High-pressure dynamics of hydrated protein in bioprotective trehalose environment.
    Physical review. E, Statistical, nonlinear, and soft matter physics, 2014, Volume: 90, Issue:4

    Topics: Animals; Chickens; Egg Proteins; Models, Chemical; Muramidase; Neutron Diffraction; Pressure; Protein Conformation; Scattering, Small Angle; Temperature; Trehalose; Water

2014
Retardation of Protein Dynamics by Trehalose in Dehydrated Systems of Photosynthetic Reaction Centers. Insights from Electron Transfer and Thermal Denaturation Kinetics.
    The journal of physical chemistry. B, 2015, Oct-29, Volume: 119, Issue:43

    Topics: Dehydration; Electron Transport; Kinetics; Molecular Dynamics Simulation; Muramidase; Photosynthetic Reaction Center Complex Proteins; Protein Conformation; Protein Denaturation; Protein Stability; Rhodobacter sphaeroides; Temperature; Trehalose

2015
Revealing the trehalose mediated inhibition of protein aggregation through lysozyme-silver nanoparticle interaction.
    Soft matter, 2015, Oct-07, Volume: 11, Issue:37

    Topics: Metal Nanoparticles; Muramidase; Protein Aggregates; Protein Binding; Protein Denaturation; Silver; Trehalose

2015
Dynamics of hydrated proteins and bio-protectants: Caged dynamics, β-relaxation, and α-relaxation.
    Biochimica et biophysica acta. General subjects, 2017, Volume: 1861, Issue:1 Pt B

    Topics: Animals; Cattle; Elasticity; Muramidase; Myoglobin; Neutron Diffraction; Proteins; Serum Albumin, Bovine; Temperature; Time Factors; Trehalose; Water

2017
Protein dynamics as seen by (quasi) elastic neutron scattering.
    Biochimica et biophysica acta. General subjects, 2017, Volume: 1861, Issue:1 Pt B

    Topics: Elasticity; Glycerol; Hydrogen; Muramidase; Myoglobin; Neutron Diffraction; Proteins; Scattering, Radiation; Spectrum Analysis; Temperature; Time Factors; Trehalose

2017
A functional natural deep eutectic solvent based on trehalose: Structural and physicochemical properties.
    Food chemistry, 2017, Feb-15, Volume: 217

    Topics: Calorimetry, Differential Scanning; Chemical Phenomena; Choline; Circular Dichroism; Hydrogen Bonding; Magnetic Resonance Spectroscopy; Molecular Structure; Muramidase; Solvents; Spectroscopy, Fourier Transform Infrared; Trehalose

2017
New insights into the interaction of proteins and disaccharides-The effect of pH and concentration.
    Biopolymers, 2017, Volume: 107, Issue:2

    Topics: Diffusion; Hydrogen-Ion Concentration; Magnetic Resonance Spectroscopy; Muramidase; Protein Binding; Sucrose; Trehalose; Viscosity

2017
Trehalose and Magnesium Chloride Exert a Common Anti-amyloidogenic Effect Towards Hen Egg White Lysozyme.
    The protein journal, 2017, Volume: 36, Issue:2

    Topics: Amyloid; Hydrophobic and Hydrophilic Interactions; Magnesium Chloride; Microscopy, Electron, Transmission; Models, Molecular; Molecular Docking Simulation; Muramidase; Protein Conformation; Protein Folding; Protein Structure, Secondary; Trehalose

2017
Influence of a Small Amount of Glycerol on the Trehalose Bioprotective Action Analyzed In Situ During Freeze-Drying of Lyzozyme Formulations by Micro-Raman Spectroscopy.
    Journal of pharmaceutical sciences, 2017, Volume: 106, Issue:10

    Topics: Chemistry, Pharmaceutical; Freeze Drying; Freezing; Glycerol; Hydrogen Bonding; Muramidase; Protein Stability; Proteins; Spectrum Analysis, Raman; Temperature; Trehalose; Water

2017
Molecular Packing, Hydrogen Bonding, and Fast Dynamics in Lysozyme/Trehalose/Glycerol and Trehalose/Glycerol Glasses at Low Hydration.
    The journal of physical chemistry. B, 2017, 10-12, Volume: 121, Issue:40

    Topics: Glycerol; Hydrogen Bonding; Molecular Dynamics Simulation; Muramidase; Protein Stability; Transition Temperature; Trehalose; Water

2017
A Printed Multicomponent Paper Sensor for Bacterial Detection.
    Scientific reports, 2017, 09-26, Volume: 7, Issue:1

    Topics: Bacteria; Biosensing Techniques; Biotechnology; DNA, Catalytic; Enzymes, Immobilized; Fluorescence; Glucans; Limit of Detection; Molecular Probes; Muramidase; Paper; Trehalose

2017
Investigation of factors affecting the stability of lysozyme spray dried from ethanol-water solutions.
    International journal of pharmaceutics, 2017, Dec-20, Volume: 534, Issue:1-2

    Topics: Chemistry, Pharmaceutical; Circular Dichroism; Ethanol; Muramidase; Polysorbates; Powders; Proteins; Temperature; Trehalose; Water

2017
Dry-powder formulations of non-covalent protein complexes with linear or miktoarm copolymers for pulmonary delivery.
    International journal of pharmaceutics, 2018, Apr-05, Volume: 540, Issue:1-2

    Topics: Administration, Inhalation; Aerosols; Drug Carriers; Drug Compounding; Drug Stability; Dry Powder Inhalers; Excipients; Glutamic Acid; Leucine; Mannitol; Molecular Structure; Muramidase; Particle Size; Polyethylene Glycols; Polyglutamic Acid; Polymers; Protein Stability; Proteolysis; Technology, Pharmaceutical; Transition Temperature; Trehalose

2018
Intra-Vial Heterogeneity in Physical Form of Mannitol in Colyophilized Binary Systems.
    Pharmaceutical research, 2018, Sep-21, Volume: 35, Issue:11

    Topics: Animals; Chickens; Crystallization; Excipients; Freeze Drying; Mannitol; Muramidase; Phase Transition; Sucrose; Trehalose

2018
Orodispersible films based on blends of trehalose and pullulan for protein delivery.
    European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V, 2018, Volume: 133

    Topics: Administration, Oral; beta-Galactosidase; Drug Compounding; Drug Delivery Systems; Freeze Drying; Glucans; Muramidase; Ovalbumin; Proteins; Tensile Strength; Trehalose

2018
Trehalose-induced slowdown of lysozyme hydration dynamics probed by EDLS spectroscopy.
    The Journal of chemical physics, 2019, Jul-07, Volume: 151, Issue:1

    Topics: Light; Muramidase; Scattering, Radiation; Spectrum Analysis; Trehalose; Water

2019
Trehalose or Sucrose: Which of the Two Should be Used for Stabilizing Proteins in the Solid State? A Dilemma Investigated by In Situ Micro-Raman and Dielectric Relaxation Spectroscopies During and After Freeze-Drying.
    Journal of pharmaceutical sciences, 2020, Volume: 109, Issue:1

    Topics: Dielectric Spectroscopy; Drug Compounding; Excipients; Freeze Drying; Ice; Muramidase; Protein Denaturation; Protein Folding; Protein Stability; Protein Structure, Secondary; Spectrum Analysis, Raman; Sucrose; Time Factors; Trehalose; Water

2020
Effect of trehalose on protein cryoprotection: Insights into the mechanism of slowing down of hydration water.
    The Journal of chemical physics, 2020, Dec-14, Volume: 153, Issue:22

    Topics: Anions; Chlorides; Kinetics; Molecular Dynamics Simulation; Muramidase; Oxygen; Trehalose; Water

2020
Impact of lyoprotectors on protein-protein separation in the solid state: Neutron- and X-ray-scattering investigation.
    Biochimica et biophysica acta. General subjects, 2022, Volume: 1866, Issue:5

    Topics: Glucose; Muramidase; Neutrons; Proteins; Scattering, Small Angle; Sorbitol; Trehalose; X-Ray Diffraction; X-Rays

2022
The Effect of Trehalose Coating for Magnetite Nanoparticles on Stability of Egg White Lysozyme.
    International journal of molecular sciences, 2022, Aug-25, Volume: 23, Issue:17

    Topics: Egg White; Magnetite Nanoparticles; Muramidase; Spectroscopy, Fourier Transform Infrared; Trehalose

2022