Page last updated: 2024-08-18

trehalose and leucine

trehalose has been researched along with leucine in 22 studies

Research

Studies (22)

TimeframeStudies, this research(%)All Research%
pre-19902 (9.09)18.7374
1990's1 (4.55)18.2507
2000's0 (0.00)29.6817
2010's13 (59.09)24.3611
2020's6 (27.27)2.80

Authors

AuthorsStudies
Haverkamp, U; Pötter, R; Wiezorek, C1
Farnsworth, DE; Feyereisen, R1
Candela, JL; Fando, JJ; García-Fernández, MC1
Boraey, MA; Feng, AL; Finlay, PR; Gwin, MA; Kuehl, PJ; Vehring, R1
Chen, KH; Gaisford, S; Kett, VL; Mueannoom, W1
Kaminskas, LM; McIntosh, MP; Meeusen, EN; Morton, DA; Sou, T; Williamson, M1
Britton, WJ; Carrigy, NB; Chan, HK; Finlay, WH; Gao, FG; Kutter, E; Leung, SS; Morales, S; Parumasivam, T; Vehring, R1
Cranston, ED; LeClair, DA; Thompson, MR; Xing, Z1
Britton, W; Chan, HK; Chang, RY; Kutter, E; Li, J; Mathai, A; Morales, S; Wong, J1
Bosquillon, C; Childerhouse, N; Coghlan, D; Falcone, FH; Mantovani, G; Nieto-Orellana, A; Rothery, M; Stolnik, S1
Boerwinkle, E; Chang, P; Coresh, J; Köttgen, A; Rebholz, CM; Selvin, E; Tin, A; Wagenknecht, LE; Yu, B; Zheng, Z1
Fahy, JV; Focaroli, S; Gitlin, I; Hastedt, JE; Healy, AM; Mah, PT; Oscarson, S1
Barona, D; D'Sa, D; Finlay, WH; Gracin, S; Gregson, FKA; Lechuga-Ballesteros, D; Melhem, O; Miles, REH; Ordoubadi, M; Reid, JP; Vehring, R1
Carrigy, NB; Connerton, IF; Kariuki, S; Liang, L; Nagel, TE; Vehring, R; Wang, H1
Fahy, JV; Focaroli, S; Gitlin, I; Hastedt, JE; Healy, AM; Lundy, R; Mah, PT; O'Connell, P; O'Mahony, TF; Oscarson, S1
Ellis, R; Kunda, NK; Muttil, P; Price, DN1
Vehring, R; Wang, H; Wang, Z1
Darabi, M; Faghihi, H; Haghighi, DM; Mirmoeini, MS; Vatanara, A1
Foged, C; Franzyk, H; Gerde, P; Harinck, L; Lokras, AG; Selg, E; Sjöberg, CO; Thakur, A; Xu, Y1
Carrigy, N; Connaughton, P; Lachacz, K; Lechuga-Ballesteros, D; Ordoubadi, M; Vehring, R; Wang, H1
Alreja, AB; Britton, WJ; Chan, HK; Khanal, D; Li, M; Nelson, DC; Tai, W; Wang, Y; Yang, H; Yk Chang, R1
Berruyer, P; Bertarello, A; Busi, B; Emsley, L; Gracin, S; Lindkvist, M; Schantz, S; Starciuc, T1

Other Studies

22 other study(ies) available for trehalose and leucine

ArticleYear
Applicability of LLD in neutron dosimetry.
    Strahlentherapie und Onkologie : Organ der Deutschen Rontgengesellschaft ... [et al], 1990, Volume: 166, Issue:2

    Topics: Glucose; Humans; Leucine; Luminescent Measurements; Mannitol; Models, Structural; Neutrons; Radiotherapy Dosage; Trehalose; Xylitol

1990
Precursor supply for insect juvenile hormone III biosynthesis in a cockroach.
    The Journal of biological chemistry, 1987, Feb-25, Volume: 262, Issue:6

    Topics: Acetyl Coenzyme A; Animals; Cockroaches; Cycloheximide; Glucose; Leucine; Mathematics; Mevalonic Acid; Sesquiterpenes; Trehalose

1987
Glycogen metabolism in Ostrea edulis (L.)--factors affecting glycogen synthesis.
    Comparative biochemistry and physiology. B, Comparative biochemistry, 1972, Dec-15, Volume: 43, Issue:4

    Topics: Animals; Carbon Isotopes; Fructose; Gills; Glucose; Glycerol; Glycogen; Hydroxybutyrates; In Vitro Techniques; Kinetics; Leucine; Ostreidae; Oxygen Consumption; Potassium; Pyruvates; Time Factors; Trehalose

1972
Mechanistic models facilitate efficient development of leucine containing microparticles for pulmonary drug delivery.
    International journal of pharmaceutics, 2011, May-16, Volume: 409, Issue:1-2

    Topics: Aerosols; Crystallization; Drug Delivery Systems; Excipients; Leucine; Lung; Microscopy, Electron, Scanning; Microspheres; Models, Theoretical; Spectrum Analysis, Raman; Time Factors; Trehalose

2011
Investigation into the effect of varying l-leucine concentration on the product characteristics of spray-dried liposome powders.
    The Journal of pharmacy and pharmacology, 2012, Volume: 64, Issue:10

    Topics: Drug Compounding; Drug Delivery Systems; Drug Stability; Excipients; Indomethacin; Leucine; Liposomes; Lung; Particle Size; Powders; Sucrose; Trehalose

2012
Spray-Dried Influenza Antigen with Trehalose and Leucine Produces an Aerosolizable Powder Vaccine Formulation that Induces Strong Systemic and Mucosal Immunity after Pulmonary Administration.
    Journal of aerosol medicine and pulmonary drug delivery, 2015, Volume: 28, Issue:5

    Topics: Aerosols; Animals; Antigens, Viral; Female; Immunity, Mucosal; Influenza Vaccines; Leucine; Lung; Particle Size; Powders; Rats; Rats, Sprague-Dawley; Trehalose; X-Ray Diffraction

2015
Production of Inhalation Phage Powders Using Spray Freeze Drying and Spray Drying Techniques for Treatment of Respiratory Infections.
    Pharmaceutical research, 2016, Volume: 33, Issue:6

    Topics: Administration, Inhalation; Aerosols; Freeze Drying; Leucine; Lung; Mannitol; Microbial Viability; Nebulizers and Vaporizers; Phage Therapy; Podoviridae; Powders; Pseudomonas; Pseudomonas Infections; Respiratory Tract Infections; Trehalose; Ultrasonics

2016
Evaluation of excipients for enhanced thermal stabilization of a human type 5 adenoviral vector through spray drying.
    International journal of pharmaceutics, 2016, Jun-15, Volume: 506, Issue:1-2

    Topics: A549 Cells; Adenoviruses, Human; Calorimetry, Differential Scanning; Dextranase; Excipients; Genetic Vectors; Humans; Humidity; Lactose; Leucine; Mannitol; Microscopy, Electron, Scanning; Powders; Temperature; Time Factors; Trehalose; X-Ray Diffraction

2016
Production of highly stable spray dried phage formulations for treatment of Pseudomonas aeruginosa lung infection.
    European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V, 2017, Volume: 121

    Topics: Aerosols; Bacteriophages; Chemistry, Pharmaceutical; Dry Powder Inhalers; Excipients; Humans; Lactose; Leucine; Powders; Pseudomonas aeruginosa; Pseudomonas Infections; Respiratory Tract Infections; Trehalose

2017
Dry-powder formulations of non-covalent protein complexes with linear or miktoarm copolymers for pulmonary delivery.
    International journal of pharmaceutics, 2018, Apr-05, Volume: 540, Issue:1-2

    Topics: Administration, Inhalation; Aerosols; Drug Carriers; Drug Compounding; Drug Stability; Dry Powder Inhalers; Excipients; Glutamic Acid; Leucine; Mannitol; Molecular Structure; Muramidase; Particle Size; Polyethylene Glycols; Polyglutamic Acid; Polymers; Protein Stability; Proteolysis; Technology, Pharmaceutical; Transition Temperature; Trehalose

2018
Serum metabolomic profile of incident diabetes.
    Diabetologia, 2018, Volume: 61, Issue:5

    Topics: Amino Acids, Branched-Chain; Asparagine; Atherosclerosis; Blood Glucose; Diabetes Mellitus, Type 2; Erythritol; Female; Glucose; Humans; Isoleucine; Lactic Acid; Leucine; Male; Maryland; Metabolome; Middle Aged; Minnesota; Mississippi; North Carolina; Prospective Studies; Risk Factors; Trehalose; Valine

2018
A Design of Experiment (DoE) approach to optimise spray drying process conditions for the production of trehalose/leucine formulations with application in pulmonary delivery.
    International journal of pharmaceutics, 2019, May-01, Volume: 562

    Topics: Administration, Inhalation; Aerosols; Desiccation; Drug Compounding; Drug Design; Leucine; Trehalose

2019
Multi-Solvent Microdroplet Evaporation: Modeling and Measurement of Spray-Drying Kinetics with Inhalable Pharmaceutics.
    Pharmaceutical research, 2019, May-14, Volume: 36, Issue:7

    Topics: Administration, Inhalation; Beclomethasone; Budesonide; Desiccation; Ethanol; Excipients; Kinetics; Leucine; Nebulizers and Vaporizers; Powders; Quantum Theory; Solvents; Trehalose; Water

2019
Spray-dried anti-Campylobacter bacteriophage CP30A powder suitable for global distribution without cold chain infrastructure.
    International journal of pharmaceutics, 2019, Oct-05, Volume: 569

    Topics: Bacteriophages; Campylobacter; Chemistry, Pharmaceutical; Desiccation; Excipients; Leucine; Powders; Trehalose

2019
The use of hydrophobic amino acids in protecting spray dried trehalose formulations against moisture-induced changes.
    European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V, 2019, Volume: 144

    Topics: Administration, Inhalation; Aerosols; Amino Acids; Chemistry, Pharmaceutical; Drug Compounding; Dry Powder Inhalers; Humidity; Hydrophobic and Hydrophilic Interactions; Leucine; Powders; Trehalose; Wettability

2019
Design and Optimization of a Temperature-Stable Dry Powder BCG Vaccine.
    Pharmaceutical research, 2019, Dec-23, Volume: 37, Issue:1

    Topics: Aerosols; Animals; BCG Vaccine; Cell Line; Cell Survival; Desiccation; Drug Compounding; Drug Stability; Drug Storage; Excipients; Female; Humans; Leucine; Mannitol; Mice, Inbred C57BL; Mycobacterium bovis; Povidone; Powders; Serum Albumin, Bovine; Temperature; Tissue Distribution; Trehalose

2019
Leucine enhances the dispersibility of trehalose-containing spray-dried powders on exposure to a high-humidity environment.
    International journal of pharmaceutics, 2021, May-15, Volume: 601

    Topics: Administration, Inhalation; Aerosols; Chemistry, Pharmaceutical; Dry Powder Inhalers; Humidity; Leucine; Particle Size; Powders; Trehalose

2021
Spray freeze drying to solidify Nanosuspension of Cefixime into inhalable microparticles.
    Daru : journal of Faculty of Pharmacy, Tehran University of Medical Sciences, 2022, Volume: 30, Issue:1

    Topics: Administration, Inhalation; Cefixime; Drug Stability; Excipients; Freeze Drying; Leucine; Particle Size; Powders; Trehalose

2022
Leucine improves the aerosol performance of dry powder inhaler formulations of siRNA-loaded nanoparticles.
    International journal of pharmaceutics, 2022, Jun-10, Volume: 621

    Topics: Administration, Inhalation; Aerosols; Animals; Dry Powder Inhalers; Excipients; Leucine; Mice; Nanoparticles; Particle Size; Powders; RNA, Small Interfering; Tissue Distribution; Trehalose; Tumor Necrosis Factor-alpha

2022
Inhalable microparticle platform based on a novel shell-forming lipid excipient and its feasibility for respirable delivery of biologics.
    European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V, 2022, Volume: 177

    Topics: Administration, Inhalation; Aerosols; Biological Products; Dry Powder Inhalers; Excipients; Feasibility Studies; Leucine; Lipids; Particle Size; Powders; Trehalose

2022
Bacteriophage endolysin powders for inhaled delivery against pulmonary infections.
    International journal of pharmaceutics, 2023, Mar-25, Volume: 635

    Topics: Administration, Inhalation; Bacteriophages; Chemistry, Pharmaceutical; Humans; Lactose; Leucine; Particle Size; Pneumonia; Powders; Respiratory Aerosols and Droplets; Trehalose

2023
Hierarchy of the Components in Spray-Dried, Protein-Excipient Particles Using DNP-Enhanced NMR Spectroscopy.
    Molecular pharmaceutics, 2023, 11-06, Volume: 20, Issue:11

    Topics: Administration, Inhalation; Aerosols; Excipients; Leucine; Magnetic Resonance Spectroscopy; Particle Size; Powders; Trehalose

2023