Page last updated: 2024-08-18

trehalose and brartemicin

trehalose has been researched along with brartemicin in 10 studies

Research

Studies (10)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (10.00)29.6817
2010's6 (60.00)24.3611
2020's3 (30.00)2.80

Authors

AuthorsStudies
Clement, LL; Drickamer, K; Jacobsen, KM; Johannsen, M; Keiding, UB; Poulsen, TB; Rambaruth, ND; Schaffert, ES1
Fujita, T; Igarashi, Y; Miyanaga, S; Mogi, T; Ohsaki, A; Saiki, I; Sakurai, H; Yanase, S1
Igarashi, Y; Jiang, YL; Liu, ZP; Miyanaga, S; Saiki, I; Tang, LQ1
Cheng, Y; Han, X; Liu, Z; Ma, X; Qu, X; Tang, L; Tian, Q; Yao, H1
Han, XZ; Igarashi, Y; Jiang, YL; Liu, ZP; Miyanaga, S; Saiki, I; Tang, LQ1
Chen, Y; Fang, F1
Foster, AJ; Ishikawa, E; Lu, X; Lynch, AT; Nagata, M; Omahdi, Z; Stocker, BL; Timmer, MSM; Yamasaki, S1
Buhl, C; Child, R; Ettenger, G; Evans, JT; Holley, D; Miller, SM; Rasheed, OK; Ryter, KT; Smith, AJ1
Foster, AJ; Kodar, K; Stocker, BL; Timmer, MSM1
Dangerfield, EM; Kodar, K; Lynch, AT; Stocker, BL; Timmer, MSM1

Other Studies

10 other study(ies) available for trehalose and brartemicin

ArticleYear
The natural product brartemicin is a high affinity ligand for the carbohydrate-recognition domain of the macrophage receptor mincle.
    MedChemComm, 2015, Apr-10, Volume: 6, Issue:4

    Topics:

2015
Brartemicin, an inhibitor of tumor cell invasion from the actinomycete Nonomuraea sp.
    Journal of natural products, 2009, May-22, Volume: 72, Issue:5

    Topics: Actinobacteria; Animals; Antineoplastic Agents; Artemisia; Colonic Neoplasms; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; Inhibitory Concentration 50; Mice; Molecular Structure; Nuclear Magnetic Resonance, Biomolecular; Trehalose

2009
Synthesis and evaluation of trehalose-based compounds as anti-invasive agents.
    Bioorganic & medicinal chemistry letters, 2011, Feb-15, Volume: 21, Issue:4

    Topics: Animals; Antineoplastic Agents; Cell Line, Tumor; Mice; Structure-Activity Relationship; Trehalose

2011
Inhibition of angiogenesis and invasion by DMBT is mediated by downregulation of VEGF and MMP-9 through Akt pathway in MDA-MB-231 breast cancer cells.
    Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 2013, Volume: 56

    Topics: Blotting, Western; Cell Line, Tumor; Down-Regulation; ErbB Receptors; Human Umbilical Vein Endothelial Cells; Humans; Matrix Metalloproteinase 9; Neovascularization, Pathologic; Proto-Oncogene Proteins c-akt; Signal Transduction; Trehalose; Vascular Endothelial Growth Factor A; Vascular Endothelial Growth Factor Receptor-2

2013
Synthesis and structure-activity relationships studies of brartemicin analogs as anti-invasive agents.
    The Journal of antibiotics, 2013, Volume: 66, Issue:9

    Topics: Animals; Antibiotics, Antineoplastic; Cell Line, Tumor; Cell Survival; Humans; Inhibitory Concentration 50; Mice; Models, Molecular; Molecular Structure; Structure-Activity Relationship; Trehalose

2013
[Design, synthesis and biological evaluation of the novel trehalose derivatives].
    Yao xue xue bao = Acta pharmaceutica Sinica, 2015, Volume: 50, Issue:6

    Topics: Antineoplastic Agents; Cell Adhesion; Cell Line, Tumor; Drug Design; Hep G2 Cells; Human Umbilical Vein Endothelial Cells; Humans; Trehalose

2015
Lipidated Brartemicin Analogues Are Potent Th1-Stimulating Vaccine Adjuvants.
    Journal of medicinal chemistry, 2018, 02-08, Volume: 61, Issue:3

    Topics: Adjuvants, Immunologic; Animals; Antigen-Presenting Cells; Glycolipids; Lectins, C-Type; Mice; Molecular Docking Simulation; Protein Conformation; Receptors, Immunologic; Th1 Cells; Trehalose; Vaccines

2018
Aryl Trehalose Derivatives as Vaccine Adjuvants for
    Journal of medicinal chemistry, 2020, 01-09, Volume: 63, Issue:1

    Topics: Adjuvants, Immunologic; Animals; Binding Sites; Cattle; Cell Line; Female; Humans; Lectins, C-Type; Mice, Inbred BALB C; Molecular Docking Simulation; Molecular Structure; Mycobacterium tuberculosis; Receptors, Immunologic; Structure-Activity Relationship; Trehalose; Tuberculosis; Tuberculosis Vaccines

2020
ortho-Substituted lipidated Brartemicin derivative shows promising Mincle-mediated adjuvant activity.
    Organic & biomolecular chemistry, 2020, 02-14, Volume: 18, Issue:6

    Topics: Animals; Cells, Cultured; Cytokines; Dose-Response Relationship, Drug; Healthy Volunteers; Humans; Ligands; Lipids; Macrophages; Mice; Mice, Inbred C57BL; Molecular Structure; Trehalose

2020
Amide-linked brartemicin glycolipids exhibit Mincle-mediated agonist activity in vitro.
    Carbohydrate research, 2022, Volume: 511

    Topics: Amides; Glycolipids; Humans; Lectins, C-Type; Trehalose

2022