trazodone has been researched along with nefazodone in 32 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 5 (15.63) | 18.2507 |
| 2000's | 14 (43.75) | 29.6817 |
| 2010's | 13 (40.63) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Greenblatt, DJ; Perloff, MD; Störmer, E; von Moltke, LL | 1 |
| Gao, F; Lombardo, F; Obach, RS; Shalaeva, MY | 2 |
| Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL | 1 |
| Lombardo, F; Obach, RS; Waters, NJ | 1 |
| Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
| Chang, G; El-Kattan, A; Miller, HR; Obach, RS; Rotter, C; Steyn, SJ; Troutman, MD; Varma, MV | 1 |
| Afshari, CA; Eschenberg, M; Hamadeh, HK; Lee, PH; Lightfoot-Dunn, R; Morgan, RE; Qualls, CW; Ramachandran, B; Trauner, M; van Staden, CJ | 1 |
| Chen, M; Fang, H; Liu, Z; Shi, Q; Tong, W; Vijay, V | 1 |
| Ballard, TE; Henderson, JL; Kalgutkar, AS; Obach, RS; Orr, ST; Ripp, SL; Scott, DO; Sun, H | 1 |
| Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ | 1 |
| Bellman, K; Knegtel, RM; Settimo, L | 1 |
| Aleo, MD; Bonin, PD; Luo, Y; Potter, DM; Swiss, R; Will, Y | 1 |
| Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K | 1 |
| Jones, LH; Nadanaciva, S; Rana, P; Will, Y | 1 |
| McBrayer, RH; Rose, FV; Ware, JC | 1 |
| Nemeroff, CB | 1 |
| Fuller, RW; Hemrick-Luecke, SK; Snoddy, HD | 1 |
| Rothschild, AJ | 1 |
| Langer, SF; Pecknold, JC | 1 |
| Chouinard, G; Margolese, HC | 1 |
| Ozkan, SA; Uslu, B | 1 |
| Addis, A; Bonari, L; Einarson, A; Johnson, Y; Koren, G; Matsui, D; Voyer-Lavigne, S | 1 |
| Mitchell, PB | 1 |
| Almási, J; Rihmer, Z | 1 |
| Atherton, J; Feng, B; Hanson, J; Kalgutkar, AS; Kostrubsky, SE; Kubik, R; Kulkarni, S; Mireles, R; Mutlib, AE; Strom, SC; Urda, E | 1 |
| Fava, M; Papakostas, GI | 1 |
| Papakostas, GI; Shelton, RC | 1 |
| Dunn, MC; Dykens, JA; Jamieson, JD; Marroquin, LD; Nadanaciva, S; Smith, AR; Will, Y; Xu, JJ | 1 |
| Dubois, J; Vanrullen, R | 1 |
| Brownlow, JA; Harb, GC; Ross, RJ | 1 |
| Khouzam, HR | 1 |
10 review(s) available for trazodone and nefazodone
| Article | Year |
|---|---|
Mechanism-based inactivation (MBI) of cytochrome P450 enzymes: structure-activity relationships and discovery strategies to mitigate drug-drug interaction risks.
Topics: Animals; Apoproteins; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Drug Discovery; Drug Interactions; Heme; Humans; Models, Biological; Pharmacokinetics; Structure-Activity Relationship; Time Factors | 2012 |
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk | 2016 |
Evolutionary trends in the pharmacotherapeutic management of depression.
Topics: Adolescent; Adult; Age Factors; Aged; Animals; Antidepressive Agents; Antidepressive Agents, Tricyclic; Child; Clinical Trials as Topic; Cyclohexanols; Decision Trees; Depressive Disorder; Double-Blind Method; Drug Administration Schedule; Humans; Piperazines; Placebos; Recurrence; Selective Serotonin Reuptake Inhibitors; Trazodone; Triazoles; Venlafaxine Hydrochloride | 1994 |
The diagnosis and treatment of late-life depression.
Topics: Age Factors; Aged; Antidepressive Agents; Anxiety Disorders; Bupropion; Cyclohexanols; Depressive Disorder; Diagnosis, Differential; Electroconvulsive Therapy; Female; Humans; Lithium; Male; Monoamine Oxidase Inhibitors; Piperazines; Selective Serotonin Reuptake Inhibitors; Sex Factors; Trazodone; Triazoles; Venlafaxine Hydrochloride | 1996 |
Therapeutic drug monitoring of non-tricyclic antidepressant drugs.
Topics: Antidepressive Agents, Second-Generation; Antidepressive Agents, Tricyclic; Bupropion; Cyclohexanols; Cytochrome P-450 Enzyme System; Drug Monitoring; Humans; Mianserin; Piperazines; Selective Serotonin Reuptake Inhibitors; Trazodone; Triazoles; Venlafaxine Hydrochloride | 2004 |
[Review of antidepressants from the TCAs to the third generation drugs].
Topics: Antidepressive Agents; Antidepressive Agents, Second-Generation; Antidepressive Agents, Tricyclic; Bupropion; Cyclohexanols; Cyclopropanes; Depressive Disorder, Major; Drug Combinations; Duloxetine Hydrochloride; Humans; Mianserin; Milnacipran; Mirtazapine; Monoamine Oxidase Inhibitors; Morpholines; Piperazines; Pyrimidines; Reboxetine; Selective Serotonin Reuptake Inhibitors; Thiophenes; Trazodone; Triazoles; Venlafaxine Hydrochloride | 2004 |
A meta-analysis of clinical trials comparing the serotonin (5HT)-2 receptor antagonists trazodone and nefazodone with selective serotonin reuptake inhibitors for the treatment of major depressive disorder.
Topics: Depressive Disorder, Major; Humans; Piperazines; Selective Serotonin Reuptake Inhibitors; Serotonin 5-HT2 Receptor Antagonists; Trazodone; Triazoles | 2007 |
Augmentation of antidepressants with atypical antipsychotics for treatment-resistant major depressive disorder.
Topics: Antidepressive Agents; Antipsychotic Agents; Aripiprazole; Benzodiazepines; Depressive Disorder, Major; Dibenzothiazepines; Dopamine D2 Receptor Antagonists; Drug Resistance; Drug Therapy, Combination; Fluoxetine; Humans; Olanzapine; Piperazines; Quetiapine Fumarate; Quinolones; Serotonin 5-HT2 Receptor Antagonists; Thiazoles; Trazodone; Triazoles | 2008 |
Treatment of Sleep Disturbances in Post-Traumatic Stress Disorder: A Review of the Literature.
Topics: Antipsychotic Agents; Cognitive Behavioral Therapy; Dreams; Eye Movement Desensitization Reprocessing; Fluvoxamine; Humans; Piperazines; Prazosin; REM Sleep Behavior Disorder; Restless Legs Syndrome; Serotonin and Noradrenaline Reuptake Inhibitors; Sleep; Sleep Apnea, Obstructive; Sleep Initiation and Maintenance Disorders; Sleep Wake Disorders; Stress Disorders, Post-Traumatic; Trazodone; Triazoles | 2015 |
Psychopharmacology of chronic pain: a focus on antidepressants and atypical antipsychotics.
Topics: Antidepressive Agents; Antidepressive Agents, Tricyclic; Antipsychotic Agents; Aripiprazole; Benzodiazepines; Bupropion; Chronic Pain; Humans; Mianserin; Mirtazapine; Olanzapine; Piperazines; Quetiapine Fumarate; Risperidone; Selective Serotonin Reuptake Inhibitors; Serotonin and Noradrenaline Reuptake Inhibitors; Thiazoles; Trazodone; Triazoles | 2016 |
2 trial(s) available for trazodone and nefazodone
| Article | Year |
|---|---|
The acute effects of nefazodone, trazodone and buspirone on sleep and sleep-related penile tumescence in normal subjects.
Topics: Adult; Analysis of Variance; Antidepressive Agents; Buspirone; Double-Blind Method; Humans; Male; Penile Erection; Piperazines; Reference Values; Sleep; Trazodone; Triazoles | 1994 |
A multicentre prospective controlled study to determine the safety of trazodone and nefazodone use during pregnancy.
Topics: Antidepressive Agents, Second-Generation; Female; Follow-Up Studies; Humans; Piperazines; Pregnancy; Pregnancy Trimester, First; Prenatal Exposure Delayed Effects; Prospective Studies; Surveys and Questionnaires; Trazodone; Triazoles | 2003 |
20 other study(ies) available for trazodone and nefazodone
| Article | Year |
|---|---|
P-glycoprotein interactions of nefazodone and trazodone in cell culture.
Topics: Antidepressive Agents, Second-Generation; ATP Binding Cassette Transporter, Subfamily B, Member 1; Biological Transport; Caco-2 Cells; Calcium Channel Blockers; Chromatography, High Pressure Liquid; Drug Interactions; Humans; Piperazines; Trazodone; Triazoles; Verapamil | 2001 |
Prediction of volume of distribution values in humans for neutral and basic drugs using physicochemical measurements and plasma protein binding data.
Topics: Blood Proteins; Chemical Phenomena; Chemistry, Physical; Half-Life; Humans; Hydrogen-Ion Concentration; Models, Biological; Pharmaceutical Preparations; Pharmacokinetics; Protein Binding | 2002 |
Prediction of human volume of distribution values for neutral and basic drugs. 2. Extended data set and leave-class-out statistics.
Topics: Algorithms; Blood Proteins; Half-Life; Humans; Hydrogen-Ion Concentration; Models, Biological; Pharmaceutical Preparations; Pharmacokinetics; Protein Binding; Statistics as Topic; Tissue Distribution | 2004 |
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling.
Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration | 2004 |
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding | 2008 |
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |
Physicochemical space for optimum oral bioavailability: contribution of human intestinal absorption and first-pass elimination.
Topics: Administration, Oral; Biological Availability; Humans; Intestinal Absorption; Pharmaceutical Preparations | 2010 |
Interference with bile salt export pump function is a susceptibility factor for human liver injury in drug development.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Assay; Biological Transport; Cell Line; Cell Membrane; Chemical and Drug Induced Liver Injury; Cytoplasmic Vesicles; Drug Evaluation, Preclinical; Humans; Liver; Rats; Reproducibility of Results; Spodoptera; Transfection; Xenobiotics | 2010 |
FDA-approved drug labeling for the study of drug-induced liver injury.
Topics: Animals; Benchmarking; Biomarkers, Pharmacological; Chemical and Drug Induced Liver Injury; Drug Design; Drug Labeling; Drug-Related Side Effects and Adverse Reactions; Humans; Pharmaceutical Preparations; Reproducibility of Results; United States; United States Food and Drug Administration | 2011 |
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests | 2013 |
Comparison of the accuracy of experimental and predicted pKa values of basic and acidic compounds.
Topics: Chemistry, Pharmaceutical; Forecasting; Hydrogen-Ion Concentration; Pharmaceutical Preparations; Random Allocation | 2014 |
Human drug-induced liver injury severity is highly associated with dual inhibition of liver mitochondrial function and bile salt export pump.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Chemical and Drug Induced Liver Injury; Humans; Male; Mitochondria, Liver; Rats; Rats, Sprague-Dawley; Severity of Illness Index | 2014 |
Development of a cell viability assay to assess drug metabolite structure-toxicity relationships.
Topics: Adenosine Triphosphate; Benzbromarone; Cell Line; Cell Survival; Chromans; Cytochrome P-450 CYP2C9; Cytochrome P-450 CYP2D6; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Humans; Pharmaceutical Preparations; Thiazolidinediones; Troglitazone | 2016 |
Evaluation of nefazodone as a serotonin uptake inhibitor and a serotonin antagonist in vivo.
Topics: Animals; Hypothalamus; Male; Methoxyhydroxyphenylglycol; Mice; Mice, Inbred ICR; Piperazines; Quipazine; Rats; Rats, Sprague-Dawley; Selective Serotonin Reuptake Inhibitors; Serotonin Antagonists; Trazodone; Triazoles | 1994 |
Priapism: trazodone versus nefazodone.
Topics: Antidepressive Agents, Second-Generation; Depressive Disorder; Humans; Male; Middle Aged; Piperazines; Priapism; Trazodone; Triazoles | 1996 |
Serotonin syndrome from addition of low-dose trazodone to nefazodone.
Topics: Antidepressive Agents, Second-Generation; Drug Interactions; Drug Therapy, Combination; Female; Humans; Hypnotics and Sedatives; Middle Aged; Piperazines; Selective Serotonin Reuptake Inhibitors; Serotonin Syndrome; Trazodone; Triazoles | 2000 |
Electroanalytical characteristics of piribedil and its differential pulse and square wave voltammetric determination in pharmaceuticals and human serum.
Topics: Algorithms; Antiparkinson Agents; Calibration; Electrochemistry; Electrodes; Humans; Hydrogen-Ion Concentration; Indicators and Reagents; Oxidation-Reduction; Piperazines; Piribedil; Solvents; Tablets; Trazodone; Triazoles | 2003 |
Inhibition of hepatobiliary transport as a predictive method for clinical hepatotoxicity of nefazodone.
Topics: Animals; Antidepressive Agents, Second-Generation; Bile Acids and Salts; Bile Canaliculi; Biological Transport; Buspirone; Cells, Cultured; Hepatocytes; Humans; Microsomes, Liver; Piperazines; Rats; Rats, Sprague-Dawley; Trazodone; Triazoles | 2006 |
In vitro assessment of mitochondrial dysfunction and cytotoxicity of nefazodone, trazodone, and buspirone.
Topics: Adenosine Triphosphate; Animals; Anti-Anxiety Agents; Antidepressive Agents, Second-Generation; Buspirone; Cell Line; Cell Respiration; Cell Survival; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Hepatocytes; Humans; Male; Membrane Potential, Mitochondrial; Metabolic Networks and Pathways; Mitochondria, Liver; Oxidative Phosphorylation; Oxygen Consumption; Piperazines; Rats; Rats, Sprague-Dawley; Trazodone; Triazoles | 2008 |
Visual trails: do the doors of perception open periodically?
Topics: Anticonvulsants; Antidepressive Agents; Female; Fructose; Hallucinogens; Humans; Lysergic Acid Diethylamide; Male; Mianserin; Middle Aged; Mirtazapine; Perceptual Disorders; Piperazines; Topiramate; Trazodone; Triazoles; Visual Perception | 2011 |