Page last updated: 2024-08-16

trazodone and morphine

trazodone has been researched along with morphine in 14 studies

Research

Studies (14)

TimeframeStudies, this research(%)All Research%
pre-19902 (14.29)18.7374
1990's3 (21.43)18.2507
2000's5 (35.71)29.6817
2010's4 (28.57)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Creveling, CR; Daly, JW; Lewandowski, GA; McNeal, ET1
Topliss, JG; Yoshida, F1
Gao, F; Lombardo, F; Obach, RS; Shalaeva, MY2
Lombardo, F; Obach, RS; Waters, NJ1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Afshari, CA; Eschenberg, M; Hamadeh, HK; Lee, PH; Lightfoot-Dunn, R; Morgan, RE; Qualls, CW; Ramachandran, B; Trauner, M; van Staden, CJ1
Bellman, K; Knegtel, RM; Settimo, L1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Morrone, LA; Pimpinella, G; Romanelli, L; Valeri, P1
Blanchi, M; De Conno, F; Panerai, AE; Ripamonti, C; Sacerdote, P; Ventafridda, V; Zecca, E1
Abate, C; Amantea, B; Belfiore, F; Brando, G; Celano, S; Celentano, L; Cuocolo, R; Orlando, C; Santangelo, E; Savoia, G1
Coudert, P; Couquelet, J; Rohet, F; Rubat, C1
Bourin, M; Hascoët, M; Ripoll, N1

Reviews

1 review(s) available for trazodone and morphine

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016

Other Studies

13 other study(ies) available for trazodone and morphine

ArticleYear
[3H]Batrachotoxinin A 20 alpha-benzoate binding to voltage-sensitive sodium channels: a rapid and quantitative assay for local anesthetic activity in a variety of drugs.
    Journal of medicinal chemistry, 1985, Volume: 28, Issue:3

    Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Anesthetics, Local; Animals; Batrachotoxins; Calcium Channel Blockers; Cyclic AMP; Guinea Pigs; Histamine H1 Antagonists; In Vitro Techniques; Ion Channels; Neurotoxins; Sodium; Tranquilizing Agents; Tritium

1985
QSAR model for drug human oral bioavailability.
    Journal of medicinal chemistry, 2000, Jun-29, Volume: 43, Issue:13

    Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship

2000
Prediction of volume of distribution values in humans for neutral and basic drugs using physicochemical measurements and plasma protein binding data.
    Journal of medicinal chemistry, 2002, Jun-20, Volume: 45, Issue:13

    Topics: Blood Proteins; Chemical Phenomena; Chemistry, Physical; Half-Life; Humans; Hydrogen-Ion Concentration; Models, Biological; Pharmaceutical Preparations; Pharmacokinetics; Protein Binding

2002
Prediction of human volume of distribution values for neutral and basic drugs. 2. Extended data set and leave-class-out statistics.
    Journal of medicinal chemistry, 2004, Feb-26, Volume: 47, Issue:5

    Topics: Algorithms; Blood Proteins; Half-Life; Humans; Hydrogen-Ion Concentration; Models, Biological; Pharmaceutical Preparations; Pharmacokinetics; Protein Binding; Statistics as Topic; Tissue Distribution

2004
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
    Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7

    Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding

2008
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Interference with bile salt export pump function is a susceptibility factor for human liver injury in drug development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2010, Volume: 118, Issue:2

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Assay; Biological Transport; Cell Line; Cell Membrane; Chemical and Drug Induced Liver Injury; Cytoplasmic Vesicles; Drug Evaluation, Preclinical; Humans; Liver; Rats; Reproducibility of Results; Spodoptera; Transfection; Xenobiotics

2010
Comparison of the accuracy of experimental and predicted pKa values of basic and acidic compounds.
    Pharmaceutical research, 2014, Volume: 31, Issue:4

    Topics: Chemistry, Pharmaceutical; Forecasting; Hydrogen-Ion Concentration; Pharmaceutical Preparations; Random Allocation

2014
Antinociceptive effects of trazodone and m-chlorophenylpiperazine (mCPP) in mice: interaction with morphine.
    General pharmacology, 1991, Volume: 22, Issue:1

    Topics: Analgesics; Animals; Antidepressive Agents; Drug Interactions; Male; Mice; Morphine; Naloxone; Piperazines; Reaction Time; Trazodone

1991
Studies on the effects of antidepressant drugs on the antinociceptive action of morphine and on plasma morphine in rat and man.
    Pain, 1990, Volume: 43, Issue:2

    Topics: Amitriptyline; Analgesia; Animals; Antidepressive Agents, Tricyclic; Clomipramine; Drug Synergism; Humans; Morphine; Nortriptyline; Rats; Rats, Inbred Strains; Trazodone

1990
[Potentiating drugs in postoperative pain control with opiates for patient controlled analgesia].
    Minerva anestesiologica, 1988, Volume: 54, Issue:4

    Topics: Analgesia; Anti-Anxiety Agents; Benzamides; Benzodiazepines; Buprenorphine; Clomipramine; Drug Synergism; Humans; Morphine; Naproxen; Nordazepam; Pain, Postoperative; Patients; Trazodone

1988
Synthesis and analgesic effects of 3-substituted 4,6-diarylpyridazine derivatives of the arylpiperazine class.
    Bioorganic & medicinal chemistry, 1997, Volume: 5, Issue:4

    Topics: Acetaminophen; Analgesics, Non-Narcotic; Analgesics, Opioid; Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Benzoquinones; Dipyrone; Dose-Response Relationship, Drug; Drug Design; Drug Interactions; Injections, Intraperitoneal; Male; Mice; Morphine; Motor Activity; Naloxone; Narcotic Antagonists; Neurotoxins; Pain; Pyrazolones; Pyridazines; Receptors, Opioid; Reference Standards; Selective Serotonin Reuptake Inhibitors; Structure-Activity Relationship; Trazodone

1997
The four-plates test: anxiolytic or analgesic paradigm?
    Progress in neuro-psychopharmacology & biological psychiatry, 2006, Volume: 30, Issue:5

    Topics: Analgesics; Analgesics, Opioid; Animals; Anti-Anxiety Agents; Antidepressive Agents, Second-Generation; Antidepressive Agents, Tricyclic; Anxiety; Dopamine Uptake Inhibitors; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Drug Interactions; Electric Stimulation; GABA Agents; Hot Temperature; Male; Mice; Morphine; Motor Activity; Nomifensine; Pain Measurement; Reaction Time; Trazodone

2006