trazodone has been researched along with diazepam in 27 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 8 (29.63) | 18.7374 |
| 1990's | 1 (3.70) | 18.2507 |
| 2000's | 10 (37.04) | 29.6817 |
| 2010's | 8 (29.63) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Creveling, CR; Daly, JW; Lewandowski, GA; McNeal, ET | 1 |
| Topliss, JG; Yoshida, F | 1 |
| Gao, F; Lombardo, F; Shalaeva, MY; Tupper, KA | 1 |
| Gao, F; Lombardo, F; Obach, RS; Shalaeva, MY | 2 |
| Johans, C; Kinnunen, PK; Söderlund, T; Suomalainen, P | 1 |
| Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL | 1 |
| Bergström, F; Giordanetto, F; Rehngren, M; Tunek, A; Wan, H | 1 |
| Lombardo, F; Obach, RS; Waters, NJ | 1 |
| Ahman, M; Holmén, AG; Wan, H | 1 |
| Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
| Chang, G; El-Kattan, A; Miller, HR; Obach, RS; Rotter, C; Steyn, SJ; Troutman, MD; Varma, MV | 1 |
| Afshari, CA; Eschenberg, M; Hamadeh, HK; Lee, PH; Lightfoot-Dunn, R; Morgan, RE; Qualls, CW; Ramachandran, B; Trauner, M; van Staden, CJ | 1 |
| Boriss, H; Braggio, S; Corbioli, S; Fontana, S; Helmdach, L; Longhi, R; Schiller, J; Vinco, F | 1 |
| Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ | 1 |
| Beaumont, K; Di, L; Maurer, TS; Smith, DA | 1 |
| Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K | 1 |
| De Gregorio, M; De Santis, AM; Favilli, S; Peruzy, AD | 1 |
| Dalton, J; Karniol, IG; Lader, M | 1 |
| Casali, L; Pozzi, E; Rampulla, C; Serra, R | 1 |
| Barclay, AM | 1 |
| Bell, F; Chan, S; Gerson, B; Pappalardo, KM | 1 |
| Midha, RN; Miller, S; Richards, HH | 1 |
| Fiorella, G; Manani, G; Piranese, A; Segatto, A; Valenti, S | 1 |
| Downing, R; Hassman, H; Rickels, K; Schweizer, E | 1 |
| Hasić, S; Jadrić, R; Kiseljaković, E; Winterhalter-Jadrić, M | 1 |
| Fitzgerald, RL; McIntyre, IM; Metushi, IG | 1 |
1 review(s) available for trazodone and diazepam
| Article | Year |
|---|---|
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk | 2016 |
3 trial(s) available for trazodone and diazepam
| Article | Year |
|---|---|
[Statistical study on a new tranquilizing agent].
Topics: Adult; Clinical Trials as Topic; Diazepam; Drug Evaluation; Female; Humans; Male; Neurotic Disorders; Piperazines; Trazodone | 1975 |
A double-blind study of trazodone and mianserin in the treatment of depression in general practice.
Topics: Adolescent; Adult; Aged; Clinical Trials as Topic; Depression; Diazepam; Dibenzazepines; Dose-Response Relationship, Drug; Double-Blind Method; Family Practice; Female; Humans; Male; Mianserin; Middle Aged; Piperazines; Psychiatric Status Rating Scales; Trazodone | 1982 |
Antidepressants for the treatment of generalized anxiety disorder. A placebo-controlled comparison of imipramine, trazodone, and diazepam.
Topics: Adult; Aged; Anxiety Disorders; Diazepam; Double-Blind Method; Drug Administration Schedule; Female; Humans; Imipramine; Male; Middle Aged; Placebos; Psychiatric Status Rating Scales; Severity of Illness Index; Trazodone; Treatment Outcome | 1993 |
23 other study(ies) available for trazodone and diazepam
| Article | Year |
|---|---|
[3H]Batrachotoxinin A 20 alpha-benzoate binding to voltage-sensitive sodium channels: a rapid and quantitative assay for local anesthetic activity in a variety of drugs.
Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Anesthetics, Local; Animals; Batrachotoxins; Calcium Channel Blockers; Cyclic AMP; Guinea Pigs; Histamine H1 Antagonists; In Vitro Techniques; Ion Channels; Neurotoxins; Sodium; Tranquilizing Agents; Tritium | 1985 |
QSAR model for drug human oral bioavailability.
Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship | 2000 |
ElogD(oct): a tool for lipophilicity determination in drug discovery. 2. Basic and neutral compounds.
Topics: 1-Octanol; Chromatography, High Pressure Liquid; Pharmaceutical Preparations; Solubility; Water | 2001 |
Prediction of volume of distribution values in humans for neutral and basic drugs using physicochemical measurements and plasma protein binding data.
Topics: Blood Proteins; Chemical Phenomena; Chemistry, Physical; Half-Life; Humans; Hydrogen-Ion Concentration; Models, Biological; Pharmaceutical Preparations; Pharmacokinetics; Protein Binding | 2002 |
Prediction of human volume of distribution values for neutral and basic drugs. 2. Extended data set and leave-class-out statistics.
Topics: Algorithms; Blood Proteins; Half-Life; Humans; Hydrogen-Ion Concentration; Models, Biological; Pharmaceutical Preparations; Pharmacokinetics; Protein Binding; Statistics as Topic; Tissue Distribution | 2004 |
Surface activity profiling of drugs applied to the prediction of blood-brain barrier permeability.
Topics: Blood-Brain Barrier; Lipid Bilayers; Micelles; Permeability; Pharmaceutical Preparations; Structure-Activity Relationship; Surface Properties | 2004 |
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling.
Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration | 2004 |
High-throughput screening of drug-brain tissue binding and in silico prediction for assessment of central nervous system drug delivery.
Topics: Animals; Brain; Central Nervous System Agents; Dialysis; Hydrophobic and Hydrophilic Interactions; In Vitro Techniques; Mice; Models, Statistical; Protein Binding; Quantitative Structure-Activity Relationship; Rats | 2007 |
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding | 2008 |
Relationship between brain tissue partitioning and microemulsion retention factors of CNS drugs.
Topics: Brain; Central Nervous System; Chromatography, Liquid; Emulsions; Mass Spectrometry | 2009 |
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |
Physicochemical space for optimum oral bioavailability: contribution of human intestinal absorption and first-pass elimination.
Topics: Administration, Oral; Biological Availability; Humans; Intestinal Absorption; Pharmaceutical Preparations | 2010 |
Interference with bile salt export pump function is a susceptibility factor for human liver injury in drug development.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Assay; Biological Transport; Cell Line; Cell Membrane; Chemical and Drug Induced Liver Injury; Cytoplasmic Vesicles; Drug Evaluation, Preclinical; Humans; Liver; Rats; Reproducibility of Results; Spodoptera; Transfection; Xenobiotics | 2010 |
Brain tissue binding of drugs: evaluation and validation of solid supported porcine brain membrane vesicles (TRANSIL) as a novel high-throughput method.
Topics: Absorption; Albumins; Animals; Brain; Brain Chemistry; Cell Membrane; Chromatography, High Pressure Liquid; Drug Evaluation, Preclinical; In Vitro Techniques; Lipids; Male; Microdialysis; Pharmaceutical Preparations; Protein Binding; Rats; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Swine; Tissue Distribution | 2011 |
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests | 2013 |
Volume of Distribution in Drug Design.
Topics: Drug Design; Half-Life; Pharmacokinetics | 2015 |
Comparative psychotropic effects of trazodone, imipramine and diazepam in normal subjects.
Topics: Acoustic Stimulation; Adult; Blood Pressure; Diazepam; Dose-Response Relationship, Drug; Evoked Potentials; Female; Galvanic Skin Response; Humans; Imipramine; Male; Piperazines; Placebos; Psychotropic Drugs; Pupil; Task Performance and Analysis; Trazodone; Tremor | 1976 |
Psychotropic drugs: influence on respiratory function.
Topics: Bronchopneumonia; Diazepam; Ethanol; Humans; Motor Activity; Psychotropic Drugs; Respiration; Time Factors; Trazodone | 1977 |
Psychotropic drugs in the elderly. Selection of the appropriate agent.
Topics: Age Factors; Aged; Antidepressive Agents; Antipsychotic Agents; Benzodiazepines; Chlordiazepoxide; Cimetidine; Diazepam; Flurazepam; Haloperidol; Humans; Kinetics; Lithium; Phenothiazines; Physostigmine; Psychotropic Drugs; Thiothixene; Trazodone | 1985 |
Trazodone: a simple, clean extraction and rapid quantification by high pressure liquid chromatography.
Topics: Chlordiazepoxide; Chromatography, High Pressure Liquid; Diazepam; Humans; Lidocaine; Trazodone | 1986 |
[Comparison of the effect of premedication with diazepam and trazodone on anesthesia induced with althesin].
Topics: Adult; Alfaxalone Alfadolone Mixture; Anesthesia; Diazepam; Female; Humans; Male; Piperazines; Preanesthetic Medication; Trazodone | 1980 |
Comparison of trazodone, diazepame and dibenzepine influences on rat brain beta-endorphins content.
Topics: Animals; Anti-Anxiety Agents; beta-Endorphin; Brain; Diazepam; Dibenzazepines; Gene Expression Regulation; Models, Chemical; Psychotropic Drugs; Rats; Rats, Wistar; Selective Serotonin Reuptake Inhibitors; Trazodone | 2007 |
Assessment and Comparison of Vitreous Humor as an Alternative Matrix for Forensic Toxicology Screening by GC-MS.
Topics: Antidepressive Agents, Second-Generation; Autopsy; Blood Chemical Analysis; Diazepam; Forensic Toxicology; Gas Chromatography-Mass Spectrometry; Humans; Pharmaceutical Preparations; Reproducibility of Results; Substance Abuse Detection; Trazodone; Vitreous Body | 2016 |