Page last updated: 2024-08-16

trazodone and clomipramine

trazodone has been researched along with clomipramine in 33 studies

Research

Studies (33)

TimeframeStudies, this research(%)All Research%
pre-19908 (24.24)18.7374
1990's11 (33.33)18.2507
2000's6 (18.18)29.6817
2010's8 (24.24)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Creveling, CR; Daly, JW; Lewandowski, GA; McNeal, ET1
Topliss, JG; Yoshida, F1
Gao, F; Lombardo, F; Obach, RS; Shalaeva, MY1
Johans, C; Kinnunen, PK; Söderlund, T; Suomalainen, P1
Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL1
Lombardo, F; Obach, RS; Waters, NJ1
Afshari, CA; Eschenberg, M; Hamadeh, HK; Lee, PH; Lightfoot-Dunn, R; Morgan, RE; Qualls, CW; Ramachandran, B; Trauner, M; van Staden, CJ1
Chang, G; Di, L; Huang, Y; Lin, Z; Liston, TE; Scott, DO; Troutman, MD; Umland, JP1
Caradonna, NP; Hallifax, D; Houston, JB; Turlizzi, E; Zanelli, U1
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ1
Bellman, K; Knegtel, RM; Settimo, L1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Carruba, MO; Mantegazza, P; Parenti, M; Picotti, GB; Ricciardi, S1
Fadda, F; Gessa, GL; Medda, L; Stefanini, E1
Cohen, LJ; Grothe, DR1
Blanchi, M; De Conno, F; Panerai, AE; Ripamonti, C; Sacerdote, P; Ventafridda, V; Zecca, E1
Aizenberg, D; Hermesh, H; Munitz, H1
Abate, C; Amantea, B; Belfiore, F; Brando, G; Celano, S; Celentano, L; Cuocolo, R; Orlando, C; Santangelo, E; Savoia, G1
Hrdina, PD1
Hollister, LE1
Avdulov, NA; Maĭsov, NI1
König, L; Kursawe, H; Lange, E; Liefke, T; Riedel, C1
Bastide, P; Coudert, P; Rubat, C; Tronche, P1
Bystritsky, A; Waikar, SV1
Jackson, CW; Lydiard, RB; Morton, WA1
Sandler, NH1
Terao, T1
Wolfe, RM1
Bonaccorso, S; Bosmans, E; De Jongh, R; Kenis, G; Lin, AH; Maes, M; Scharpé, S; Song, C1
Handa, M; Hayashi, H; Kanazawa, F; Kubo, C; Mine, K; Tsuchida, O; Yamamoto, H1
Abdel-Salam, OM; El-Shenawy, SM; Nofal, SM1
Altamura, AC; Buoli, M; Caldiroli, A; Cremaschi, L; Fiorentini, A; Pozzoli, SM; Rovera, C1
Buchberger, W; Emhofer, L; Himmelsbach, M; Klampfl, CW; Reichl, B1

Reviews

4 review(s) available for trazodone and clomipramine

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016
Major depression: its recognition and treatment. Part 2. Second-generation and newer antidepressants.
    American pharmacy, 1992, Volume: NS32, Issue:11

    Topics: Antidepressive Agents; Bupropion; Clomipramine; Depression; Female; Fluoxetine; Humans; Male; Maprotiline; Selective Serotonin Reuptake Inhibitors; Trazodone

1992
'Second generation' antidepressant drugs.
    Psychosomatics, 1981, Volume: 22, Issue:10

    Topics: Amoxapine; Antidepressive Agents; Antidepressive Agents, Tricyclic; Clomipramine; Humans; Maprotiline; Mianserin; Nomifensine; Trazodone; Viloxazine

1981
Antidepressant withdrawal reactions.
    American family physician, 1997, Volume: 56, Issue:2

    Topics: Adult; Amitriptyline; Antidepressive Agents; Antidepressive Agents, Tricyclic; Clomipramine; Cyclohexanols; Drug Administration Schedule; Female; Humans; Male; Monoamine Oxidase Inhibitors; Selective Serotonin Reuptake Inhibitors; Substance Withdrawal Syndrome; Trazodone; Venlafaxine Hydrochloride

1997

Trials

3 trial(s) available for trazodone and clomipramine

ArticleYear
Inert placebo versus active medication. Patient blindability in clinical pharmacological trials.
    The Journal of nervous and mental disease, 1994, Volume: 182, Issue:9

    Topics: Clinical Trials as Topic; Clomipramine; Depressive Disorder; Double-Blind Method; Humans; Obsessive-Compulsive Disorder; Placebos; Psychiatric Status Rating Scales; Research Design; Trazodone; Treatment Outcome

1994
Negative immunoregulatory effects of antidepressants: inhibition of interferon-gamma and stimulation of interleukin-10 secretion.
    Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 1999, Volume: 20, Issue:4

    Topics: Adult; Antidepressive Agents, Second-Generation; Antidepressive Agents, Tricyclic; Antiviral Agents; Clomipramine; Enzyme-Linked Immunosorbent Assay; Female; Humans; Interferon-gamma; Interleukin-10; Male; Recombinant Proteins; Selective Serotonin Reuptake Inhibitors; Sertraline; Trazodone

1999
Is trazodone more effective than clomipramine in major depressed outpatients? A single-blind study with intravenous and oral administration.
    CNS spectrums, 2019, Volume: 24, Issue:2

    Topics: Administration, Intravenous; Administration, Oral; Adult; Aged; Antidepressive Agents; Clomipramine; Depressive Disorder, Major; Female; Humans; Male; Middle Aged; Single-Blind Method; Trazodone

2019

Other Studies

26 other study(ies) available for trazodone and clomipramine

ArticleYear
[3H]Batrachotoxinin A 20 alpha-benzoate binding to voltage-sensitive sodium channels: a rapid and quantitative assay for local anesthetic activity in a variety of drugs.
    Journal of medicinal chemistry, 1985, Volume: 28, Issue:3

    Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Anesthetics, Local; Animals; Batrachotoxins; Calcium Channel Blockers; Cyclic AMP; Guinea Pigs; Histamine H1 Antagonists; In Vitro Techniques; Ion Channels; Neurotoxins; Sodium; Tranquilizing Agents; Tritium

1985
QSAR model for drug human oral bioavailability.
    Journal of medicinal chemistry, 2000, Jun-29, Volume: 43, Issue:13

    Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship

2000
Prediction of human volume of distribution values for neutral and basic drugs. 2. Extended data set and leave-class-out statistics.
    Journal of medicinal chemistry, 2004, Feb-26, Volume: 47, Issue:5

    Topics: Algorithms; Blood Proteins; Half-Life; Humans; Hydrogen-Ion Concentration; Models, Biological; Pharmaceutical Preparations; Pharmacokinetics; Protein Binding; Statistics as Topic; Tissue Distribution

2004
Surface activity profiling of drugs applied to the prediction of blood-brain barrier permeability.
    Journal of medicinal chemistry, 2004, Mar-25, Volume: 47, Issue:7

    Topics: Blood-Brain Barrier; Lipid Bilayers; Micelles; Permeability; Pharmaceutical Preparations; Structure-Activity Relationship; Surface Properties

2004
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling.
    Current drug discovery technologies, 2004, Volume: 1, Issue:4

    Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration

2004
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
    Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7

    Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding

2008
Interference with bile salt export pump function is a susceptibility factor for human liver injury in drug development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2010, Volume: 118, Issue:2

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Assay; Biological Transport; Cell Line; Cell Membrane; Chemical and Drug Induced Liver Injury; Cytoplasmic Vesicles; Drug Evaluation, Preclinical; Humans; Liver; Rats; Reproducibility of Results; Spodoptera; Transfection; Xenobiotics

2010
Species independence in brain tissue binding using brain homogenates.
    Drug metabolism and disposition: the biological fate of chemicals, 2011, Volume: 39, Issue:7

    Topics: Animals; Brain; Dogs; Guinea Pigs; Humans; Macaca fascicularis; Mice; Rats; Species Specificity

2011
Comparison of cryopreserved HepaRG cells with cryopreserved human hepatocytes for prediction of clearance for 26 drugs.
    Drug metabolism and disposition: the biological fate of chemicals, 2012, Volume: 40, Issue:1

    Topics: Cell Line, Tumor; Cryopreservation; Female; Hepatocytes; Humans; Male; Metabolic Clearance Rate; Pharmaceutical Preparations; Predictive Value of Tests

2012
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests

2013
Comparison of the accuracy of experimental and predicted pKa values of basic and acidic compounds.
    Pharmaceutical research, 2014, Volume: 31, Issue:4

    Topics: Chemistry, Pharmaceutical; Forecasting; Hydrogen-Ion Concentration; Pharmaceutical Preparations; Random Allocation

2014
Effect of etoperidone on the depletion of brain 5-hydroxytryptamine and catecholamines induced respectively by p-chloromethamphetamine and 6-hydroxydopamine in rats.
    Pharmacological research communications, 1979, Volume: 11, Issue:2

    Topics: Animals; Antidepressive Agents; Brain; Catecholamines; Clomipramine; Desipramine; Dopamine; Hydroxydopamines; Male; Methamphetamine; Norepinephrine; Piperazines; Rats; Serotonin; Time Factors; Trazodone

1979
Selective inhibition of serotonin uptake by trazodone, a new antidepressant agent.
    Life sciences, 1976, Jun-15, Volume: 18, Issue:12

    Topics: Animals; Biological Transport; Brain; Brain Stem; Cerebral Cortex; Clomipramine; Corpus Striatum; Dopamine; Kinetics; Male; Norepinephrine; Piperazines; Rats; Serotonin; Synaptosomes; Trazodone

1976
Studies on the effects of antidepressant drugs on the antinociceptive action of morphine and on plasma morphine in rat and man.
    Pain, 1990, Volume: 43, Issue:2

    Topics: Amitriptyline; Analgesia; Animals; Antidepressive Agents, Tricyclic; Clomipramine; Drug Synergism; Humans; Morphine; Nortriptyline; Rats; Rats, Inbred Strains; Trazodone

1990
Trazodone treatment in clomipramine-resistant obsessive-compulsive disorder.
    Clinical neuropharmacology, 1990, Volume: 13, Issue:4

    Topics: Adult; Analysis of Variance; Clinical Trials as Topic; Clomipramine; Depression; Drug Resistance; Female; Humans; Lithium; Lithium Carbonate; Male; Middle Aged; Obsessive-Compulsive Disorder; Prospective Studies; Trazodone

1990
[Potentiating drugs in postoperative pain control with opiates for patient controlled analgesia].
    Minerva anestesiologica, 1988, Volume: 54, Issue:4

    Topics: Analgesia; Anti-Anxiety Agents; Benzamides; Benzodiazepines; Buprenorphine; Clomipramine; Drug Synergism; Humans; Morphine; Naproxen; Nordazepam; Pain, Postoperative; Patients; Trazodone

1988
Inhibition of sodium-dependent [3H]imipramine binding in rat brain by serotonin and serotonin uptake inhibitors.
    European journal of pharmacology, 1988, Mar-29, Volume: 148, Issue:2

    Topics: Animals; Cell Membrane; Cerebral Cortex; Clomipramine; Fluoxetine; Imipramine; Male; Rats; Receptors, Serotonin; Serotonin; Sodium; Trazodone

1988
[Atypical antidepressants: effect on synaptosomal uptake of serotonin and GABA].
    Biulleten' eksperimental'noi biologii i meditsiny, 1981, Volume: 92, Issue:11

    Topics: Animals; Antidepressive Agents; Brain; Carbazoles; Carbolines; Clomipramine; Depression, Chemical; Desipramine; gamma-Aminobutyric Acid; Imipramine; In Vitro Techniques; Oxazines; Piperazines; Rats; Serotonin; Synaptosomes; Trazodone

1981
[Clinical investigation comparing trazodone and clomipramine].
    Psychiatrie, Neurologie, und medizinische Psychologie, 1980, Volume: 32, Issue:12

    Topics: Clomipramine; Depressive Disorder; Humans; Piperazines; Trazodone

1980
Behavioural profile of two potential antidepressant pyridazine derivatives including arylpiperazinyl moieties in their structure, in mice.
    The Journal of pharmacy and pharmacology, 1995, Volume: 47, Issue:2

    Topics: 5-Hydroxytryptophan; Analgesia; Animals; Antidepressive Agents; Apomorphine; Behavior, Animal; Blepharoptosis; Citalopram; Clomipramine; Drug Interactions; Fluoxetine; Hypothermia; Imipramine; Injections, Intraperitoneal; Injections, Subcutaneous; Male; Mice; Models, Molecular; Motor Activity; Naloxone; Piperazines; Pyridazines; Reserpine; Structure-Activity Relationship; Swimming; Trazodone; Yohimbine

1995
Pharmacologic management of obsessive-compulsive disorder.
    Southern medical journal, 1994, Volume: 87, Issue:3

    Topics: 1-Naphthylamine; Antidepressive Agents; Anxiety Disorders; Clomipramine; Depression; Dopamine; Fluoxetine; Fluvoxamine; Humans; Obsessive-Compulsive Disorder; Selective Serotonin Reuptake Inhibitors; Serotonin; Sertraline; Synaptic Transmission; Trazodone

1994
Tardive dyskinesia associated with fluoxetine.
    The Journal of clinical psychiatry, 1996, Volume: 57, Issue:2

    Topics: Adult; Clomipramine; Drug Therapy, Combination; Dyskinesia, Drug-Induced; Fluoxetine; Humans; Male; Obsessive-Compulsive Disorder; Trazodone

1996
Rapid synergistic effects of lithium and antidepressants.
    Psychopharmacology, 1995, Volume: 122, Issue:2

    Topics: Adult; Antidepressive Agents; Antidepressive Agents, Second-Generation; Clomipramine; Depressive Disorder; Drug Synergism; Female; Humans; Lithium; Trazodone

1995
Antidepressant treatment of patients with diffuse esophageal spasm: a psychosomatic approach.
    Journal of clinical gastroenterology, 1999, Volume: 28, Issue:3

    Topics: Adult; Aged; Aged, 80 and over; Antidepressive Agents, Second-Generation; Antidepressive Agents, Tricyclic; Clomipramine; Esophageal Spasm, Diffuse; Female; Follow-Up Studies; Humans; Male; Manometry; Middle Aged; Pressure; Psychological Tests; Psychosomatic Medicine; Retrospective Studies; Trazodone; Treatment Outcome

1999
Evaluation of the anti-inflammatory and anti-nociceptive effects of different antidepressants in the rat.
    Pharmacological research, 2003, Volume: 48, Issue:2

    Topics: Amitriptyline; Analysis of Variance; Animals; Antidepressive Agents; Carrageenan; Clomipramine; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Electroshock; Fluoxetine; Imipramine; Inflammation; Male; Pain; Pain Measurement; Rats; Rats, Sprague-Dawley; Sertraline; Trazodone

2003
Uptake and metabolism of the antidepressants sertraline, clomipramine, and trazodone in a garden cress (Lepidium sativum) model.
    Electrophoresis, 2018, Volume: 39, Issue:9-10

    Topics: Antidepressive Agents; Chromatography, High Pressure Liquid; Clomipramine; Lepidium sativum; Metabolome; Plant Leaves; Plant Roots; Sertraline; Tandem Mass Spectrometry; Trazodone

2018