Page last updated: 2024-08-16

trazodone and aripiprazole

trazodone has been researched along with aripiprazole in 13 studies

Research

Studies (13)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's2 (15.38)29.6817
2010's7 (53.85)24.3611
2020's4 (30.77)2.80

Authors

AuthorsStudies
Lombardo, F; Obach, RS; Waters, NJ1
Chang, G; Di, L; Huang, Y; Lin, Z; Liston, TE; Scott, DO; Troutman, MD; Umland, JP1
Ballard, TE; Henderson, JL; Kalgutkar, AS; Obach, RS; Orr, ST; Ripp, SL; Scott, DO; Sun, H1
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ1
Balogh, I; Kim, HY; Koczok, K; Korade, Z; Liu, W; Mirnics, K; Porter, NA; Tallman, KA; Xu, L1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
He, Y; Liu, Y; Shen, J; Shi, W; Wang, Y; Wang, Z; Wu, C; Wu, S; Yang, F; Zheng, W1
Papakostas, GI; Shelton, RC1
Khouzam, HR1
Balogh, I; Garbett, KA; Genaro-Mattos, TC; Koczok, K; Korade, Z; Liu, W; Mirnics, K; Porter, NA; Tallman, KA1
Anderson, A; Balog, M; Genaro-Mattos, TC; Korade, Z; Mirnics, K1
Anderson, AC; Balog, M; Heffer, M; Korade, Z; Mirnics, K1
Anderson, A; Balog, M; Korade, Z; Mirnics, K; Porter, NA; Tallman, KA1

Reviews

4 review(s) available for trazodone and aripiprazole

ArticleYear
Mechanism-based inactivation (MBI) of cytochrome P450 enzymes: structure-activity relationships and discovery strategies to mitigate drug-drug interaction risks.
    Journal of medicinal chemistry, 2012, Jun-14, Volume: 55, Issue:11

    Topics: Animals; Apoproteins; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Drug Discovery; Drug Interactions; Heme; Humans; Models, Biological; Pharmacokinetics; Structure-Activity Relationship; Time Factors

2012
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016
Augmentation of antidepressants with atypical antipsychotics for treatment-resistant major depressive disorder.
    Acta psychiatrica Scandinavica, 2008, Volume: 117, Issue:4

    Topics: Antidepressive Agents; Antipsychotic Agents; Aripiprazole; Benzodiazepines; Depressive Disorder, Major; Dibenzothiazepines; Dopamine D2 Receptor Antagonists; Drug Resistance; Drug Therapy, Combination; Fluoxetine; Humans; Olanzapine; Piperazines; Quetiapine Fumarate; Quinolones; Serotonin 5-HT2 Receptor Antagonists; Thiazoles; Trazodone; Triazoles

2008
Psychopharmacology of chronic pain: a focus on antidepressants and atypical antipsychotics.
    Postgraduate medicine, 2016, Volume: 128, Issue:3

    Topics: Antidepressive Agents; Antidepressive Agents, Tricyclic; Antipsychotic Agents; Aripiprazole; Benzodiazepines; Bupropion; Chronic Pain; Humans; Mianserin; Mirtazapine; Olanzapine; Piperazines; Quetiapine Fumarate; Risperidone; Selective Serotonin Reuptake Inhibitors; Serotonin and Noradrenaline Reuptake Inhibitors; Thiazoles; Trazodone; Triazoles

2016

Other Studies

9 other study(ies) available for trazodone and aripiprazole

ArticleYear
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
    Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7

    Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding

2008
Species independence in brain tissue binding using brain homogenates.
    Drug metabolism and disposition: the biological fate of chemicals, 2011, Volume: 39, Issue:7

    Topics: Animals; Brain; Dogs; Guinea Pigs; Humans; Macaca fascicularis; Mice; Rats; Species Specificity

2011
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests

2013
The Effect of Small Molecules on Sterol Homeostasis: Measuring 7-Dehydrocholesterol in Dhcr7-Deficient Neuro2a Cells and Human Fibroblasts.
    Journal of medicinal chemistry, 2016, Feb-11, Volume: 59, Issue:3

    Topics: Animals; Cell Line; Dehydrocholesterols; Dose-Response Relationship, Drug; Fibroblasts; Homeostasis; Humans; Mice; Molecular Conformation; Neurons; Oxidoreductases Acting on CH-CH Group Donors; Small Molecule Libraries; Sterols; Structure-Activity Relationship

2016
Synthesis and biological investigation of triazolopyridinone derivatives as potential multireceptor atypical antipsychotics.
    Bioorganic & medicinal chemistry letters, 2020, 04-15, Volume: 30, Issue:8

    Topics: Antipsychotic Agents; Dose-Response Relationship, Drug; Humans; Models, Molecular; Molecular Structure; Pyridines; Receptor, Serotonin, 5-HT1A; Receptor, Serotonin, 5-HT2A; Structure-Activity Relationship; Triazoles

2020
Vulnerability of
    Journal of lipid research, 2017, Volume: 58, Issue:11

    Topics: Adult; Aripiprazole; Cholesterol; Enzyme Inhibitors; Female; Fibroblasts; Humans; Male; Middle Aged; Mutation; Oxidoreductases Acting on CH-CH Group Donors; Smith-Lemli-Opitz Syndrome; Trazodone

2017
Individual and simultaneous treatment with antipsychotic aripiprazole and antidepressant trazodone inhibit sterol biosynthesis in the adult brain.
    Journal of lipid research, 2022, Volume: 63, Issue:8

    Topics: Animals; Antidepressive Agents; Antipsychotic Agents; Aripiprazole; Brain; Mice; Oxidoreductases Acting on CH-CH Group Donors; Sterols; Trazodone

2022
Effects of Psychotropic Medication on Somatic Sterol Biosynthesis of Adult Mice.
    Biomolecules, 2022, 10-21, Volume: 12, Issue:10

    Topics: Adult; Animals; Antidepressive Agents; Antipsychotic Agents; Aripiprazole; Desmosterol; Humans; Lanosterol; Mice; Trazodone

2022
Chronic Aripiprazole and Trazodone Polypharmacy Effects on Systemic and Brain Cholesterol Biosynthesis.
    Biomolecules, 2023, 08-28, Volume: 13, Issue:9

    Topics: Animals; Aripiprazole; Brain; Cholesterol; Chromatography, Liquid; Female; Humans; Male; Mice; Phytosterols; Polypharmacy; Sterols; Tandem Mass Spectrometry; Trazodone

2023