trapoxin a has been researched along with laq824 in 1 studies
| Studies (trapoxin a) | Trials (trapoxin a) | Recent Studies (post-2010) (trapoxin a) | Studies (laq824) | Trials (laq824) | Recent Studies (post-2010) (laq824) |
|---|---|---|---|---|---|
| 8 | 0 | 1 | 70 | 1 | 19 |
| Protein | Taxonomy | trapoxin a (IC50) | laq824 (IC50) |
|---|---|---|---|
| Histone deacetylase 3 | Homo sapiens (human) | 0.0607 | |
| Histone deacetylase 4 | Homo sapiens (human) | 0.0848 | |
| Histone deacetylase 1 | Homo sapiens (human) | 0.0512 | |
| Histone deacetylase 7 | Homo sapiens (human) | 0.3987 | |
| Histone deacetylase 2 | Homo sapiens (human) | 0.0506 | |
| Polyamine deacetylase HDAC10 | Homo sapiens (human) | 0.0309 | |
| Histone deacetylase 11 | Homo sapiens (human) | 0.0303 | |
| Histone deacetylase 8 | Homo sapiens (human) | 0.0974 | |
| Histone deacetylase 6 | Homo sapiens (human) | 0.0545 | |
| Histone deacetylase 9 | Homo sapiens (human) | 0.0308 | |
| Histone deacetylase 5 | Homo sapiens (human) | 0.0569 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (100.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Atadja, P; Bair, KW; Bontempo, J; Cesarz, D; Chandramouli, N; Chen, R; Cheung, M; Cornell-Kennon, S; Dean, K; Diamantidis, G; France, D; Green, MA; Howell, KL; Kashi, R; Kwon, P; Lassota, P; Martin, MS; Mou, Y; Perez, LB; Remiszewski, SW; Sambucetti, LC; Sharma, S; Smith, T; Sorensen, E; Taplin, F; Trogani, N; Versace, R; Walker, H; Weltchek-Engler, S; Wood, A; Wu, A | 1 |
1 other study(ies) available for trapoxin a and laq824
| Article | Year |
|---|---|
N-hydroxy-3-phenyl-2-propenamides as novel inhibitors of human histone deacetylase with in vivo antitumor activity: discovery of (2E)-N-hydroxy-3-[4-[[(2-hydroxyethyl)[2-(1H-indol-3-yl)ethyl]amino]methyl]phenyl]-2-propenamide (NVP-LAQ824).
Topics: Acetyltransferases; Acrylamides; Animals; Antineoplastic Agents; Body Weight; Cell Division; Dose-Response Relationship, Drug; Drug Design; Drug Screening Assays, Antitumor; Enzyme Inhibitors; Female; Histone Acetyltransferases; Humans; Hydroxamic Acids; Indicators and Reagents; Mice; Mice, Nude; Molecular Conformation; Neoplasm Transplantation; Saccharomyces cerevisiae Proteins | 2003 |